Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX , Tukwila, WA Tel: (425) CLIA License # 50D

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1 Accession # ELEMENT PANEL PHAN HUYNH, DC 5106 HUMMINGBIRD COURT Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX , Tukwila, WA Tel: (425) CLIA License # 50D s For: DENISE FAZ Age: 45 Sex:Female Received : 12/26/2007 Completed: 12/31/2007 Reported : 12/31/2007 Dx Code:Not Provided BAKERSFIELD CA USA Tel: Fax: Patient's Tel: Specimen Collected:12/22/2007 Test Description Ref Values ASI TAP * Adrenal Stress Index Free Cortisol Rhythm 01:00-03:00 AM 4 Normal 4-19 nm 07:00-09:00 AM 9 Depressed nm 11:00-01:00 PM 6 Normal 5-10 nm 03:00-05:00 PM 1* Depressed 3-8 nm 07:00-09:00 PM 1 Depressed 3-7 nm Cortisol Burden: The cortisol burden reflects the area under the cortisol curve. This is an indicator of overall cortisol exposure, where high values favor a catabolic state, and low values are sign of adrenal deterioration. Further investigation is warranted Figure 2. The Cortisol release inducers fall into 4 broad categories shown in the adjacent flowchart. Long term adrenal axis maintenance and restoration, require optimization of all the cortisol inducers. Remarks: Depressed morning cortisol, < 13 nm, is suggestive of marginal HPA (Hypothalamic-Pituitary-Adrenal) performance. Normal rhythms exhibit highest cortisol value for the day at 7-8 AM Figure 1. Circadian Cortisol Profile 1-3 AM 8 AM Noon 4 PM 7 PM Reference Ranges Patient s Figure 2. 1 Copyright DTI

2 Accession: Test Description Ref Values DHEA Dehydroepiandrosterone 1 Depressed DHEA Adults (M/F): 3-10 ng/ml Figure 3. Cortisol-DHEA Correlation Figure 3 shows your cortisol-dhea correlation was in: Zone 4 - Maladapted phase II This zone represents a marginal cortisol output with reduced DHEA levels reflecting a minimal adrenal reserve. The production of the precursor pregnenolone is usually limited and the adrenal cortex may show hypertrophic changes. Under stress most patients in maladaptation phase II will have a suboptimal response to stress. This suboptimal response is any response not consistent with a normal diurnal cortisol production pattern. This condition is usually the outcome of chronic and protracted stress exposure Reference DHEA CORTISOL-DHEA CORRELATION ZONES 1. Adapted to stress. 2. Adapted with DHEA slump. 3. Maladapted Phase I. 4. Maladapted Phase II. 5. Non-adapted, Low Reserves 6. High DHEA. 7. Adrenal Fatigue. ISN Insulin Fasting 6 Normal Normal: 3-12 uiu/ml Figure 4b. Serum Insulin - Time Curve Shaded area is optimal period of post-prandial collection. 2 Copyright DTI

3 Accession: Test Description Ref Values P17-OH 17-OH Progesterone 34 Normal Adults Optimal: pg/ml Borderline: pg/ml Elevated: >130 pg/ml Figure 5. Adrenal Steroid Synthesis Pathway Figure 5. MB2S Total Salivary SIgA 10 Depressed Normal: mg/dl Borderline: mg/dl A depressed mucosal SIgA may be attributed to one or Basic Facts About SIgA more of the following reasons: 1. Secretory IgA (SIgA) is secreted by the various mucosal 1- Excessive chronic cortisol output causes a reduction surfaces. It is mostly a dimeric molecule. Less than 2% of Saliva is in the number of SIgA producing immunocytes. of serum origin. The secretory component of SIgA stabilizes it Appropriate restorative treatments have been shown to against enzymatic and bacterial degradation. produce incremental improvements in SIgA. 2. The main functions of SIgA include Immune Exclusion, Viral 2- Excessive sympathetic activity causes inhibition of and Toxin Neutralization, Plasmid Elimination, and Inhibition of SIgA release from the mucosal immunocytes. Bacterial Colonization. SIgA immune complexes are not 3- Chronic deficits in cortisol and/or DHEA levels. inflamatory to the mucosal surfaces. 4- Possible systemic deficit in capacity to produce IgA - an inherited problem. Rule out possibility with a serum 3. Production of SIgA is adversely affected by stress which is IgA test. A normal finding rules out this possibility. mediated by increased cortisol and/or catecholamine levels. FI4 Gliadin Ab, SIgA 4 Negative Borderline: U/ml Positive: >15 U/ml Notes on Gliadin Ab Test Gliadins are polypeptides found in wheat, rye, oat, barley, and other grain glutens, and are toxic to the intestinal mucosa in susceptible individuals. Healthy adults and children may have a positive antigliadin test because of subclinical gliadin intolerance. Some of their symptoms include mild enteritis, occasional loose stools, fat intolerance, marginal vitamin and mineral status, fatigue, or accelerated osteoporosis. Scan. J. Gastroenterol. 29:248(1994). 3 Copyright DTI

4 Accession: Test Description Ref Values 4 Copyright DTI

5 Accession # ELEMENT PANEL PHAN HUYNH, DC 5106 HUMMINGBIRD COURT Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX , Tukwila, WA Tel: (425) CLIA License # 50D s For: DENISE FAZ Age: 45 page: 1 Received : 12/26/2007 Completed: 12/31/2007 Reported : 12/31/2007 Gender:Female PHP1. BAKERSFIELD CA USA Tel: Fax: Postmenopausal Hormone panel -- Short Patient's Tel: Specimen Collected: 12/22/2007 Copyright DTI Hormone Notes Reference Ranges TTF - Testosterone 9 Normal Borderline: 5-7 pg/ml Normal: 8-20 pg/ml E1 - Estrone 14 Normal for Age 40-49: pg/ml E2 - Estradiol 11 Postmenopause-No HRT: 1-4 pg/ml HRT Target Range: 5-13 pg/ml Follicular: 5-13 pg/ml Luteal: 7-20 pg/ml E3 - Estriol 13 Postmenopause-No HRT: 7-18 pg/ml HRT Target Range: pg/ml Cycling Female: pg/ml P1 - Progesterone >1000 Postmenopause-No HRT: 5-95 pg/ml HRT Target Range: pg/ml Follicular: pg/ml Luteal: pg/ml More interpretation and the action plan on following pages. Diagnosis Code: Not Provided To The Lab. Please Note: All examples of patient treatment or therapy are for illustrative and/or educational purpose. Use this report in context of the clinical picture before initiating hormone or other therapies.

6 Accession: Breast Proliferation Index (BPI) TM TM Uterine Proliferation Index (UPI) page: Optimal ZONE Enhanced Proliferation. 2. High Proliferative Potential. 3. Hormone Overload. 4. Pro-Proliferative. 2 1 PrA (EA + P1 Activity) 5. Mild Androgen Dominance. 6. Frank Androgen Excess. 7. Female Hormone Deficit. 8. Hypogonadism with Atrophy. Legend Patient PrA - Proliferative Activity EA - Estrogenic Activity Optimal ZONE Enhanced Proliferation. 2. High Proliferative Potential. 3. Potentially Proliferative. 4. Accentuated Hormone Imbalance. 4 2 EA (E2 Equivalents) Mild Imbalance. 6. Pre-Atrophic. 7. Pro-Atrophic. 8. Atrophic. Copyright DTI

7 Accession: page: 3

8 Accession # ELEMENT PANEL PHAN HUYNH, DC 5106 HUMMINGBIRD COURT Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX , Tukwila, WA Tel: (425) CLIA License # 50D Subject: DENISE FAZ Age: 45 Received : 12/26/2007 Completed: 12/31/2007 Reported : 12/31/2007 Gender:Female BAKERSFIELD CA USA Tel: Fax: Patient's Tel: Specimen Collected: 12/22/2007 Code Test Name Values Provisional Ranges STP Saliva Thyroid Study ftsh Thyroid stimulating hormone 41 Normal Borderline Low: niu/ml Normal: niu/ml Borderline High: niu/ml ft4 L-Thyroxine 0.19 Normal Normal: ng/dl ft3 Triiodo-thyronine 0.32 Normal Borderline Low: pg/ml Normal: pg/ml TPO Thyroid Microsomal Ab, SIgA Negative Normal: Negative The Saliva Thyroid tests are intended for research use only and not as stand alone diagnostic tests. Additional tests may be required. s should be contextualized into the over all clinical picture. These values reflect unbound "Tissue-Delivery" concentrations which may not neccessarily correlate with serum hormone levels. 1 Copyright DTI

9 Accession # ELEMENT PANEL PHAN HUYNH, DC 5106 HUMMINGBIRD COURT Diagnos-Techs, Inc. Clinical & Research Laboratory PO BOX , Tukwila, WA Tel: (425) CLIA License # 50D s For: DENISE FAZ Age: 45 Received : 12/26/2007 Completed: 12/31/2007 Reported : 12/31/2007 Gender:Female BAKERSFIELD CA USA Tel: Fax: Patient's Tel: Specimen Collected: 12/22/2007 Code Test Name / Notes Reference Values/Key CS3 Diagnosis Code: Fungal Cu. Isol. & I.D. Not Provided To The Lab. Source not specified: Swab culture +1 trace amount of Candida albicans isolated. +1=Trace +2=Light +3=Moderate +4=Abundant +5=Confluent Please Note: All examples of patient treatment or therapy are for illustrative and/or educational purpose. Use this report in context of the clinical picture before initiating hormone or other therapies. 1 Copyright DTI

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