Improving access to medicines for patients in lower-income countries

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1 Improving access to medicines for patients in lower-income countries AHBS II Dakar November 6, 2017

2 Our access strategy: tailoring our approach to income segments Income segments 1 High Income Upper-middle Income Middle Income Low Income Poor % of population size 7 % 9 % 13 % 55 % 16% Access approaches Traditional for-profit business-led approach (original brands & generics) Patient assistance programs Generics Differential pricing Patient assistance programs Philanthropy 1 PEW Research Center with data from World Bank PovcalNet (data 2011) 1

3 : Capitalizing on proven industry-leading programs Novartis Access Malaria Initiative Healthy Family programs SMS for Life NGO supply We offer commercial solutions to support public health needs and increase patient reach We devise novel approaches to tackle infectious and chronic disease and partner with public and private actors to build capacity We aim to become a partner of choice in improving access to healthcare for patients in lower income countries 2

4 Novartis Access Fighting the growing burden of chronic diseases A portfolio of medicines for governments, NGOs and institutional customers at USD 1 per treatment per month Drive availability and affordability of high-quality medicines 15 on- and off-patent medicines targeting the main chronic diseases and breast cancer Work to ensure standard of care Collaboration with governments and NGOs in an effort to ensure patients are properly diagnosed and treated Cardiovascular Diseases Breast Cancers Respiratory Diseases Diabetes Diagnosis Treatment Long term, the objective is to become commercially sustainable 3

5 Novartis Access: Partnerships are essential to success Humanitarian Sector Co-create community care models for chronic conditions in Dadaab & Kakuma refugee camp Diabetes and hypertension treatments (Syrian refugees in Lebanon) Partner: Kenya Red Cross Society, ICRC, Kenya Red Cross Faith Based Organizations (FBOs) Women s cancers Initiatives to improve diagnostics for breast cancer and safe treatments ASCP increase IHC testing paired with provision of affordable treatment via NA portfolio American Cancer Society training providers on safe handling and usage of chemo therapy Monitoring & Evaluation Independent & transparent M&E on access and social impact of NCD medicines in countries in Kenya Partner: Boston University 4 FBOs provide care to vulnerable patients, complementing public sector coverage CHAK and KCCB (Kenya) training providers and conducting screenings in rural & poor communities CBC (Cameroon) screens and educates patients on NCDs through the Know Your Numbers campaign

6 Novartis Access 20 months update 415,000 monthly treatments delivered to date Cameroon sixth country to sign MoU after Kenya, Ethiopia, Rwanda, Pakistan and Uganda 7 partnerships with faith-based organizations, NGOs, academia and research organizations Capacity-building activities started in Kenya and Cameroon to screen and diagnose people for diabetes and hypertension Discussions ongoing in 10+ countries across 3 continents to introduce the program 462 products submitted to health authorities for regulatory approval in 23 countries (175 approvals to date) 5

7 Back-up 6

8 Malaria Initiative: Helping to accelerate malaria elimination What is it? The Novartis Malaria Initiative aims to meet patient needs through four key pillars: treatment, access, capacity building, research & development History-making The Novartis Malaria Initiative is one of the largest access-to-medicine programs in the industry, with more than 800 million treatments delivered without profit since million malaria cases and 429,000 malaria deaths in 2015 WHO 2016: Gold standard Novartis has a long heritage in antimalarial drug development First child-friendly ACT High-strength ACT for reduced pill burden Today, we lead two of the four most advanced malaria development programs worldwide 7

9 Healthy Family: Health education and care for rural communities What is it? The Novartis Healthy Family programs use innovative business models that build local, sustainable capabilities for healthcare including access to healthcare, education, infrastructure and distribution for the Bottom of the Pyramid (BoP) population around the world Impacts at scale Since 2010, programs in India, Kenya, Vietnam and Indonesia have reached more than 30 million people with health education > 4.3 million health workers are needed worldwide Success on the ground More than 3 million patients have been diagnosed and treated at health camps WHO 2016: 8

10 SMS for Life: Using mobile and digital technology to increase quality of care What is it? SMS for Life 2.0 uses smartphones and tablet computers to track stock levels of essential medicines. It also allows for disease monitoring and can be used to train health workers at remote facility level The program launched in Kaduna State, Nigeria end of 2016 and will be deployed in Zambia in 2017 Supply chain challenges lead to medicine stock-outs in rural facilities in many lower income countries Technology for change Originally launched in 2009, SMS for Life was designed to manage stock-outs of antimalarials. The enhanced 2.0 version now also looks at HIV treatments and vaccines and will be extended to treatments against noncommunicable diseases 9

11 NGO supply: partnering with global NGOs for better access What is it? Sandoz has a very broad range of products which are offered to major NGO partners including UNICEF, MSF, UNDP, ICRC, The IDA Foundation. The program is committed to reaching more patients in low income and poor countries. 6 million lives could be saved if equitable access was provided to just 13 life-saving commodities Our commitment to paediatric populations We are committed to making our pediatric Amoxicillin treatments available to developing countries; to date, treatment courses have been delivered to UNICEF. This commitment supports the UN Commission on Life-Saving Commodities for Women and Children. UNFPA: 10

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