INÉ POHĽADY NA DIÉTNE OPATRENIA V KARDIOVASKULÁRNEJ PREVENCII IX. ANGIOLOGICKÝ DEŇ NÚSCH 25.novembra 2016
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1 INÉ POHĽADY NA DIÉTNE OPATRENIA V KARDIOVASKULÁRNEJ PREVENCII IX. ANGIOLOGICKÝ DEŇ NÚSCH 25.novembra 2016 Viliam BADA III.Interná klinika LF UK, UNB Nemocnica akademika Ladislava Dérera Limbová 5 Bratislava - Kramáre
2 Iľja Iľjič MEČNIKOV Alexander Iosifovič IGNATOVSKIJ Nikolaj Nikolajevič ANIČKOV Nobel Price 1908 Phagocytosis decrease animal protein Ivanivka,Charkovská gubernija- Paríž (71r) IM Smolensk-Belehrad (80r) St Petersburg- Moskva (79) IM
3 DIET & HEALTH HYPOTHESIS CHOLESTEROL And SATURATED FATS MEDITERRANEAN DIET SOUTH OF NAPLES, January Ancel Benjamin KEYS PIOPPI Here purchased a House And SPENT here : 28 years
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6 IN CONCLUSION OF STUDY CLAS 1984 (COLESTIPOL + NIACÍN) David H. BLANKENHORN DECREASING CHOLESTEROL LEVEL there are signals of POSSIBLE REVERSIBILITY of ATHEROSCLEROSIS
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8 HARVARD MEDICAL SCHOOL, Boston, Mass GUIDE to HEALTHY EATING prof. Walter Willet. EGGS are O.K.! NO CORRELATION BETWEEN HIGH EGG CONSUMPTION AND CARDIOVASCULAR MORTALITY Hu FB, et al A prospective study of EGG consumption and RISK of cardiovascular disease in men and women JAMA 1999;281: Years Long prospective epidemiological study : men women together
9 After 15 years from 1984!
10 CHOLESTEROL CHOLE žlč STEROS- pevný OL- alkohol ÚLOHY Vitamín D Steroidné hormóny Žlčové kyseliny ŠTRUKTÚRA A FUNKCIA ŽIVOČÍŠNYCH MEMBRÁN Permeabilita, Fluidita, Izolácia, Konduktivita, SYNTÉZA CHOLESTEROLU V KAŽDEJ BUNKE
11 3,5 x Celkový Počet Buniek Celkové množstvo Cholesterolu : 35 g Denne sa syntetizuje asi 1 g v POTRAVE je Cholesterol ESTERIFIKOVANÝ ZLE SA REZORBUJE, má Minimálny vplyv na Hladinu Cholesterolu Cholesterol sa RECYKLUJE Enterohepatálnym Cyklom (Cholesterol v žlči nie je esterifikovaný)
12 FATHER OF FACTORS of RISK Framingham Hert Study CHOLESTEROL + SATURATED FATS CHOLESTEROL IS A BIOLOGICAL RUST WHICH CHOKE THE FLOW OF THE BLOOD MRFIT men Low Fat High Carb diet Non significant increased mortality in exp group FOR EACH 1% mg /dl DROP OF CHOLESTEROL 11% INCREASED CORONARY AND TOTAL MORTALITY Jeremiah STAMLER 27.X.1919 FAT MUST MAKE PEOPLE FAT FAT= 9 CALORIES /gram CARBOHYDRATES = 4 CAL/gram MEDITERRANEAN DIET IN PIOPPI NEIGHBOUR TO A. KEYS
13 LOW FAT + HIGH CARB DIET AND OBESITY USDA (US DEPARTMENT OF AGRICULTURE)
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16 CARDIOVASCULAR DISEASE IN EUROPE EPIDEMIOLOGICAL UPDATE 2014 AGE STANDARDIZED M O R T A L I T Y CVD total 10 year change CHD 10year change DK Males 173,5-46 % 67,1-57% SK Males 551,8-17% 333,8-9% DK Females 110,8-43% 32, 6-59% SK Females 360,2-18% 209,5-11% Nichols M, Townsend N, Scarborough P, Rayner M. University of Oxford Europ Heart J 2014; 35: , ( November )
17 SAMEDI 2014
18 NINA TEICHOLZ Simon & Schuster NY 2014, THE BIG FAT SURPRISE, New York Times Bestseller Why Butter,Meat and Cheese Belong in Healthy Diet
19 ALEŠ HRDLIČKA Humpolec 1869* Washington Phys Antropologist Director of Dept Of Antrophology Smithsonian Inst. Washington DC Stay in on Southwest USA and Mexico Between PIMA Indios Seemed Healthy lived to old Age over 90 He examined over 2000 Native Americans no atherosclerosis, no tumors, no dementia On Diet mainly on Meat from Buffalos US Census in 1900 NATIVE AMER CENTENARIANS WHITE M:224 /mil M : 3 /mil Ž :254/ mil Ž : 6/mil 460-page Report for Smithsonian Institute Washington DC
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21 Dariush MOZAFFARIAN Dean of the TUFTS FRIEDMAN SCHOOL OF NUTRITION SCIENCE & POLICY AND THE JEAN MAYER CHAIR AND PROFESSOR OF NUTRITION IN RECENT YEARS REMERKABLE SCIENTIFIC ADVANCES, HAVE MADE CLEAR, THAT HOW WE EAT IS THE LEADING CAUSE OF POOR HEALTH, AND HOW WE PRODUCE OUR FOOD THE LEADING CAUSE OF ENVIROMENTAL INJURY ON THE PLANET. CREATING ENOUGH HEALTHY AND EQUITABLY FOOD IS TOP GLOBAL PRIORITY THIS IS NUTRITION S TIME
22 Dariush Mozaffarian, DIET and HEART DISEASE What Every Cardiologist Should Know American College of Cardiology, Expert Analysis, May 2016, Circulation 2016 SINGLE MAJOR CAUSE OF POOR HEALTH IS POOR DIET Dairy products : whole fat vs low fat, personal preference Fish Red meats 2-3 servings per day : Oily Fish, mackerel,herring,sardines,sprats 2 or more servings per week : Fresh or frozen BEEF,PORK,LAMB 2-3 servings per week Industrial Trans Fat : DON T EAT (partialy hydrogenated vegetable oils) Sugar-Sweetened beverages: DON T DRINK ALCOHOL :Up to 1 drink for women 2 drinks for men
23 VYTENIS ANDRIUKAITIS KOMISÁR EÚ PRE ZDRAVIE A BEZPEČNOSŤ POTRAVÍN 20. marec 2015
24 PLENÁRNE ZASADNUTIE EURÓPSKEHO PARLAMENTU 25.X.2016,STRASBOURG TRANS FATS (TFAS) VYTENIS ANDRIUKAITIS KOMISÁR EÚ PRE ZDRAVIE A BEZPEČNOSŤ POTRAVÍN TFAS majú NESPOCHYBNITEĽNE negatívny účinok ako ŽIADNA INÁ potravina, Ročná KVS mortalita v EU asi ľudí. JE POTREBNÉ ĎALŠIE PRESKÚMANIE!! Uskutočňuje sa Dopadová štúdia, ako má Komisia EU postupovať. FDA : TFAS sa všeobecne NEPOVAŽUJÚ za BEZPEČNÉ, od júna 2018 sa majú ZAKÁZAŤ Hlasovanie EP má 751 členov neprítomných 108, zdržanie 38, proti 19 (165) za 586
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