Psychosocial Determinants of Quality of Life and CI Outcome in Older Adults
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1 April 1 23, 2018 Psychosocial Determinants of Quality of Life and CI Outcome in Older Adults Howard W. Francis, MD, MBA, FACS Professor and Chief Duke Head and Neck Surgery & Communication Sciences Presented by: Howard Francis
2 Disclosure Member, Surgical Advisory Boards: Advanced Bionics Corporation Med-El Corporation Cochlear Corporation
3 Speech Perception Gain with Age 1 yr change in HINT Speech Scores by Age at CI Change in HINT speech score from pre-ci to post-ci N=83 Lin et al, Medicine, Age at CI (years)
4 Residual Hearing Helps HINT Speech Score (%) Pre-CI HINT Speech Score <40% Mean Post-CI Score: 77.3% CMS Pre-CI HINT Speech Score 40-60% Mean Post-CI Score: 89.7% FDA Pre-CI Lin et al, Medicine, 2012 Post-CI Pre-CI Post-CI
5 Health Utility Index (HUI) Gain by Age Francis et al, Laryngoscope, 2002 Change in HUI Change in HUI Age at at CI CI (yrs) (yrs)
6 Change in HUI Association between HUI and Speech Perception Gains Francis et al, Laryngoscope, 2002 Change in HUI Monosyllabic Monosyllabic Words Words Speech Speech Discrimination Discimination 6 mos at (%) 6 mos (%) r=0.55; p<.005 <65 y.o. at CI >=65 y.o. at CI
7 Hearing Loss and Aging Outcomes Independent risk factor for: Hospitalization Physical disability Cognitive decline Increased mortality Lin et al, J Gerontol A Biol Sci Med Sci, 2011; Genther et al, JAMA, 2013; Lin et al, JAMA Int Med, 2013;
8 April 23, Hearing Loss and Aging Outcomes Potential Mediators Attention burden Depression Isolation
9 April 9 23, 2018 Hearing Loss and Aging Outcomes Isolation Loneliness score Higher baseline in CI recipients Improves at 6-12m after CI UCLA Loneliness Score 12 m Change HA CI Contrera et al., Laryngoscope, 2017 Baseline
10 April 10 23, 2018 The Older CI Candidate Hearing deprivation and aging effects SEVERITY AGING Hearing Deprivation Effects TIME? Cochlear Implant Intervention Quality of Engagement Outcome
11 Conceptual Model for CI Outcomes in Older Adults Clark et al, JAGS, Hearing Acuity -SDS in Quiet -SDS in Noise -Attentional Burden -Emotional Response 6 CHARACTERISTICS OF THE INDIVIDUAL 4 1 BIOLOGICAL, PHYSIOLOGICAL & DEVICE VARIABLES 2 SYMPTOM STATUS 2 3 FUNCTIONAL STATUS 3 : PHYSICAL PSYCHOLOGICAL ROLE SOCIAL 4 GENERAL HEALTH PERCEPTION 5 HRQL 1 -Duration HL -Pre-op Hearing -Device Integrity -Surgical Factors -Device Programming 7 CHARACTERISTICS OF THE ENVIRONMENT 5 Adopted from Wilson and Cleary, JAMA, 1995
12 April 12 23, 2018 Study of Psychosocial Determinants I Francis et al, (Triological Thesis) Laryngoscope, 2014 JHH Retrospective, N= % female Dependent Variables: Surgical results full insertion complications No. Subjects Age at CI (y) Open-set SP CNC words, CNC phonemes, HINT sentences in quiet baseline, 3, 6 & 12m
13 April 13 23, 2018 Study of Psychosocial Determinants I Francis et al, (Triological Thesis) Laryngoscope, 2014 Independent variables Age at CI Proportion of life using HA Education Living Arrangements Depression Co-morbidities (Charlson Index) Missing SP data
14 Time Course of Speech Perception Gains Francis et al, (Triological Thesis) Laryngoscope, 2014 Pre-CI 3 m 6 m 12 m
15 Correlates of SP Gain Francis et al, (Triological Thesis) Laryngoscope, Speech Perception (%) Early Gains (3m): PropLifeHA (Baseline SP) 10 0 C0 (baseline) C1 C2 C3
16 Correlates of Early vs Late SP Gain (6-12 m) Francis et al, (Triological Thesis) Laryngoscope, 2014 Speech Perception (%) Late Gains: Education status, Residential status, Depression status, Co-morbidities Early Gains (3m): PropLifeHA (Baseline SP) C0 (baseline) C1 C2 C3
17 Correlates of 12 m SP Gain Francis et al, (Triological Thesis) Laryngoscope, Speech Perception (%) m Gains: Education status Residential status Co-morbidities (Baseline SP) (Missing data) 10 0 C0 (baseline) C1 C2 C3
18 Correlates of Speech Perception Gain (with addition of data missingness*) Francis et al, (Triological Thesis) Laryngoscope, Speech Perception (%) Late Gains: Education status, Residential status, Depression status, Co-morbidities Early Gains (3m): PropLifeHA* (Baseline SP) Duration HL 12m Gains: Education status Residential status* Co-morbidities* (Baseline SP) (Missing data) Female gender Family involvement 0 C0 (baseline) C1 C2 C3
19 Conceptual Model for CI Outcomes in Older Adults Clark et al, JAGS, 2012 Francis et al, Triological Thesis, CHARACTERISTICS OF THE INDIVIDUAL Education Status Co-morbidities History of depression Gender 1 BIOLOGICAL, PHYSIOLOGICAL Sound deprivation 2 SYMPTOM STATUS Speech perception 3 FUNCTIONAL STATUS: PHYSICAL PSYCHOLOGICAL ROLE SOCIAL 4 GENERAL HEALTH PERCEPTION 5 HRQL Adopted from Wilson and Cleary, JAMA, CHARACTERISTICS OF THE ENVIRONMENT Residential Status Family Involvement
20 April 20 23, 2018 Study of Psychosocial Determinants II Tang et al., Ear and Hearing, 2017 Evaluate: Individual and environmental determinants of CI outcome Emotional intelligence Comfort with technology Engagement with aural rehabilitation Resident and co-domicile status
21 April 21 23, 2018 Study of Psychosocial Determinants II Tang et al., Ear and Hearing, 2017 Prospective study - Recent JHH CI cohort >65y at CI in previous 18m N=55 Dependent variables (at1y; avg 13.9m) Speech perception (AzBio) Quality of Life (Glasgow Benefit Inventory) Independent variables (surveys and EMR) age, health status, exposure to aural rehabilitation, trait emotional intelligence (EI), comfort with technology, and living arrangements
22 April 23, Study of Psychosocial Determinants II RESULTS Higher education 27% higher SP scores (p<.05) Cohabitation 22% higher SP scores (p<.05) Less significant with education Engagement with aural rehabilitation Higher GBI score (+15.8, p<.05) Comfort with technology (tablet users) 18% higher SP performance (p<.05) Borderline significant with education status Relevance to appropriate device use
23 April 23, Study of Psychosocial Determinants II RESULTS No effect of Age Emotional Intelligence Higher than average Not predictive of SP or QoL at 1 year Missing Data Associated with mild cognitive impairment (N=5) Associated with lower social engagement scores on GBI
24 Conceptual Model for CI Outcomes in Older Adults Tang et al., Ear and Hearing, in press Characteristics of the individual: HIGHER EDUCATION LEVEL COMFORT WITH TECHNOLOGY Biological, physiological & Device variables B Speech perception B B A Functional status: Physical Psychological Role Social B General health perception HRQL B Characteristics of the environment: COHABITATION
25 April 25 23, 2018 Conclusions Older adults of all ages can benefit from CI Variable outcomes influenced by delayed intervention, psychosocial factors and general health Limitations to access and ability to engage in practice and rehabilitation services need to be addressed
26 April 26 23, 2018 Re-Shaping Our Approach Communication and QoL outcomes: f(x) Atrophic effects of sensory deprivation + Downstream health and psychosocial effects of hearing loss + Other aging effects
27 Proposed Policy and Practice Early intervention Tailored Rehabilitation Patient Family and caregivers New Strategic Alliances Local Care and Companion Networks Enhanced social engagement Family support CI Manufacturers and Community Audiologists Technological support
28 Thank you
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