HELIX. Mobile Wellness and Research. Medication Guide August Updated: June For questions, please contact Helix Customer Service:

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1 HELIX Mobile Wellness and Research Medication Guide August Updated: June For questions, please contact Helix Customer Service: TEXT/CALL: customerservice@helixbayarea.com

2 Testosterone: Injections

3 TESTOSTERONE DEMONSTRATION: TESTOSTERONE INJECTIONS: Many male patients at Helix do testosterone injections. Most are prescribed anywhere from 0.15 to 0.3 ml twice per week. Your bottle will show your dosage, but reach out to customer service with any questions. Your testosterone bottle should last 3 to 4 months TESTOSTERONE SYRINGE: The testosterone syringe is 1/2 needle. 3. TESTOSTERONE DOSAGE: Most patients will inject anywhere between 0.15 to 0.30 ml, twice per week. Read your orange/blue prescription bottle for exact amounts. For example, if the injection dosage is 0.35 ml, then the needle should be filled to the 35 hash-mark (as shown in the photo). An injection of 0.3 ml, should be filled to the 30 hash-mark, etc. INJECTION SITES: You can inject testosterone anywhere in the body. For best results we recommend: 1. Vastus Lateralis - Outer Thigh area, right above the thigh muscle. 2. Abdomen - Abdomen injections may cause irritation - switch areas if so. 3. Gluteus Maximus/ Buttocks Area - be sure to avoid the sciatic nerve. 4. No matter the site, make sure the needle goes all the way into your skin. ROTATE INJECTION AREAS: Over-Injecting in one spot will cause irritation. If you inject in the thigh, for example, please be sure to rotate between left and right thighs. Anatomy picture courtesy: 5. ROOM TEMP: Keep testosterone in a closed cabinet at room temp.

4 TESTOSTERONE DEMONSTRATION CONTINUED: FILLING THE SYRINGE: Testosterone is an oil and is not easy to withdraw. Instructions for the quickest way to withdraw: 1. Hold the testosterone bottle upside down. 2. Take your syringe and inject some air into the testosterone bottle - then withdraw the syringe s plunger. 3. Continually withdraw the syringe s plunger, and then slowly push the plunger back in (this PUMPS the testosterone oil out). 4. Do not push any testosterone back in while pumping. 5. Pause between each pump - when you withdraw, hold and let the oil collect, as each pump will create a suction. Do not pump quickly - pump slowly and pause in between pumps. 6. Your full amount should be in the needle within a few minutes.

5 HCG: Injections and Mixing

6 HCG DEMONSTRATION: HCG DOSAGES: Most male patients at Helix are prescribed HCG injections. Most are prescribed 300 iu (0.3 ml) twice per week. HCG is an amino-acid peptide. By injecting HCG, patients should help their natural fertility & testosterone systems stay active. In addition, our in-house research shows that HCG should naturally boost human growth hormone, as well as replenish adrenals and thyroid HCG SYRINGE: The HCG syringe is 5/16 in needle size. It is the smaller needle. HCG DOSAGE: Most patients will inject 0.3 ml of HCG, twice per week. Please read your orange/blue prescription bottle for exact amount. For example, for an injection of 0.3 ml, the syringe should be filled to the 30 hash-mark (as shown in the photo). An injection of 0.2 ml, should be filled to the 20 hash-mark, etc. 3. FRIDGE: HCG needs to be kept in the fridge. INJECTION SITES: HCG can be injected anywhere. For best results, we recommend: 1. Vastus Lateralis - Outer Thigh, directly above the muscle. 2. Deltoid/Shoulder - the outside part of where your arm meets shoulder. This site could cause stinging, but it should subside quickly. 3. Abdomen/Stomach area Deltoid picture courtesy: Minnesota Department of Health INJECTION ROTATION: Do your best to rotate injection sites, but HCG is not as tough on the body as other injections. MORNING: HCG should act as an upper. We recommend that HCG injections be done in the morning or start of day.

7 HCG DEMONSTRATION CONTINUED: HCG BREAKS: HCG will run out early. Most patients will have 4-months worth of testosterone, but HCG will run out after 2-months of use. This is normal. Too much HCG may cause the Leydig Cells to get overstimulated, which is why we create HCG breaks. However, patients who feel better on HCG, and would like to stay on continually, can subscribe to one of our add-on programs for a small monthly fee, where we would provide extra HCG. Overall, all patients should see how they feel after taking breaks from HCG, because scientifically, that may be ideal. Our doctors are happy to discuss continual use of HCG if you decide that is best for your care.

8 HCG MIXING: HCG MIXING: HCG will come in a bottle, as a powder. Mix it as follows: 1. Account for supplies: there should be (a) one HCG glass-vial with powder in it, (b) one large syringe for mixing and (c) a bottle of bacteriostatic water. 2. Use the large syringe and withdraw 5 ml of bacteriostatic water into it. 3. Inject 5 ml of bac-water into the HCG glass-vial. 4. Do NOT shake the HCG glass-vial - just roll it around in your palm. 5. Put the HCG bottle in the fridge after injecting. Bacteriostatic Water Syringe: You will be putting 5 ML of bacteriostatic water into your HCG glass-vial. Take the large syringe and fill it slightly above the 5 marker - this marker represents 5 ml.

9 Sermorelin/GHRP-2: Injections and Mixing

10 SERMORELIN/GHRP-2 DEMONSTRATION: Sermorelin/GHRP-2 DOSAGES: Most women patients at Helix are prescribed Sermorelin/GHRP-2. Men can also receive this as an add-on. Sermorelin/GHRP-2 is prescribed to help heal the hypothalamus and pituitary - with the idea that it should help re-stimulate hormone systems, re-balance them, and release the hormones that are most needed. Sermorelin/GHRP-2 also should naturally and greatly boost human growth hormone - likely its finest benefit SERMORELIN SYRINGE: Depending on preference, the Sermorelin/GHRP-2 needle is either 1/2 or 5/16 3. SERMORELIN DOSAGE: Sermorelin/GHRP-2 dosages: Women s Dosage: 0.12 four times weekly - that means women should fill the needle to the 12 hash-mark (as shown in the photo). Men s Dosage: 0.10 to 0.20 three or four times per week - fill the needle somewhere between the 10 and 20 hashmark. INJECTION SITES: Sermorelin/GHRP2 Injections depend on your chosen needle size: 4. INJECTION ROTATION: All patients should rotate injections areas (left thigh, then right thigh, etc). 1. 1/2 Needle: For the 1/2 needle, inject the Vastus Lateralis, Outer Thigh, directly above the muscle. 2. 5/16 Needle: For the 5/16 needle, inject the Deltoid/Shoulder area - the outside part of where your arm meets shoulder. This site could cause stinging, but it should subside quickly. 5. Deltoid tends to have finer results, but each area should NOTE: Many longevity experts FRIDGE: be effective, per our advocate injecting Sermorelin/ Sermorelin/GHRP-2 needs research, as long as you use GHRP2 into fat, but our in-house to go into the fridge, after the right needle for the area. studies show best results with being mixed. deltoid and thigh injections.

11 Sermorelin/GHRP-2 MIXING: SERMORELIN/GHRP-2 MIXING: Sermorelin/GHRP-2 will come in a glass-vial, with dry powder in it. Mix it as follows: 1. Account for supplies: there should be (a) one Sermorelin-GHRP-2 glass vial with powder in it, (b) a large syringe for mixing and (c) a bottle of bacteriostatic water. 2. Use the large needle and withdraw 7.5 ml of bacteriostatic water into it. 3. Inject 7.5 ml of bac-water into the Sermorelin/ GHRP-2 glass vial. 4. Do NOT shake the Sermorelin/GHRP-2 glass vial - just roll it around in your palm. 5. Store the Sermorelin/GHRP-2 bottle in the fridge after injecting. Bacteriostatic Water Syringe: You will be putting 7.5 ML of bacteriostatic water into your Sermorelin/GHRP-2 glass vial. Take the large syringe and fill it slightly above the 7.5 marker - this marker represents 7.5 ml.

12 Adrenals, Thyroid and Progesterone Medications

13 Adrenal, Thyroid, Progesterone Medications: By subscribing to Helix, we will monitor your adrenals, thyroid and progesterone (in addition to testosterone and estrogen). If your adrenal, thyroid or progesterone levels are deficient, in accordance with Helix s protocols, then we will likely issue meds. For adrenals, thyroid and progesterone, the medications issued tend to be capsules that are swallowed, not injections. Your prescribing practitioner at Helix will let you know if any capsules are prescribed. Of note, the primary Helix protocol (which includes HCG for men, and Sermorelin/GHRP2 for women), should already help balance thyroid and adrenals, according to our inhouse research.

14 MISC NOTES

15 COMBINING INJECTIONS: Injections can be combined. For convenience, you may put prescriptions into the same syringe and inject once. However, try to follow our guidance in terms of what time of day certain prescriptions should be injected. A few notes: 1. Testosterone should always be the first prescription to go into the syringe (so it is the last injected into the body). 2. Glutathione (if you do the add-on) should always go into the syringe last (so its the first med injected into the body). 3. We highly recommend that HCG, B12, and B- Complex be injected in the morning (or start of day), whereas Sermorelin/GHRP-2 should be done at night. Testosterone can be done at any time.

16 SHARPS DISPOSAL: When disposing of needles, please be sure to put the orange-cap back on the needle, so that it is properly covered. Disposing of a covered needle in your trash is allowed in many states and cities. However, laws on this matter can vary by state, county, and city. We advise checking laws for your local area. In regard to areas that do require medical waste disposal, we advise the following steps: 1. Obtain a plastic container - of note, plastic detergent containers (Tide, Snuggle, etc) are fine for this use. The container does not have to be an official medical sharps container or red container. 2. Either in black marker, or on sticker-label tape, write SHARPS BIOHAZARD - DO NOT RECYCLE on the plastic container and dispose your capped-needles in there. Be sure to close the container between use. 3. Once the container is full (or close to it), take it to a local sharps disposal location. Many Sheriff Offices and Senior Centers offer free sharps container disposal. For a list of local sharps container drop-offs, feel free to visit: Sharps disposal is not required in many states, but we advise being prepared.

17 HELIX ADD-ONS: Helix MWR offers the following add-ons. Please contact Helix s customer service if you are interested in having your Helix doctor add-on these meds to your protocol: HUMAN GROWTH HORMONE: SERMORELIN/GHRP-2: $155 monthly, with $155 deposit Sermorelin/GHRP-2 is a powerful peptide-combo that should greatly boost your human growth hormone (HGH) levels. In our in-house research, we have also found that this peptide-combo may re-balance many hormones throughout the body. The standard Helix protocol should already give your HGH levels a boost, but Sermorelin/GHRP-2 should increase it. HCG: BOOST - $15 monthly add-on, with $15 deposit FERTILITY - $25 monthly add-on, with $25 deposit The HCG BOOST add-on will give you an additional bottle of HCG, so that you re on it continually during your Helix protocols. The HCG FERTILITY add-on is two additional bottles of HCG, so that you are on it continually, at higher dosages, for the purpose of maintaining male fertility. B12: $25 monthly, with $25 deposit The B12 add-on is a bottle of injectable B12, which can be dosed with any of your meds. Great for those who feel better with B12. B-COMPLEX & MIC: $25 monthly, with $25 deposit The B-Complex with MIC is an injectable bottle of B-Complex with MIC (Methionine Inositol Choline). This add-on should aid longevity and potentially help metabolism and energy. GLUTATHIONE: $35 monthly, with $35 deposit An injectable bottle of Glutathione that can be combined with other injections. It should enhance longevity.

18 FINAL THOUGHTS: Everyone at Helix is honored and proud to serve you! We love what we do. And we love our patients. If you have questions, always feel free to reach out to our customer service team, where we promise a swift answer. We are honored to have you on board - Miguel Ali Founder, Helix MWR Helix Customer Service: TEXT/CALL: CustomerService@HelixBayArea.com

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