Cognitive Health in the Workplace
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1 Mild Cognitive Impairment: Uncovering the Impact on an Ageing Workforce Cognitive Health in the Workplace Dr Jenny Barnett Director, Healthcare Innovation
2 CANTAB Corporate Health Validated by 30 years of leading neuroscience research from Cambridge Cognition, the leading global provider of cognitive assessment software in: Academic Research : 1,500+ published studies worldwide Clinical Drug Trials : 162 global trials Healthcare Provision: 25,000+ NHS assessments Combining leading neuroscience and expertise in occupational health. Helping employers and providers measure and manage cognitive health using the latest digital tools. CANTAB Corporate Health All rights reserved Page 2
3 What is cognition? Memory & learning Remember contacts, actions appointments Learn new names, procedures, systems Attention Ability to concentrate Juggle competing demands Processing speed Rapidly understanding information Decision-making Weigh up evidence Risk- and time- appropriate decisions CANTAB Corporate Health All rights reserved Page 3
4 Everyday memory problem questionnaire Real-world consequences of cognitive failures 120 Stockbroker taking inappropriate financial risks Air traffic controller responding too slowly to an emerging risk Sales lead forgetting contacts or failing to follow up on agreed actions Programmer writing poor code 0 R=0.686; p< CANTAB PAL total trials adjusted CANTAB Corporate Health All rights reserved Page 4
5 Mild cognitive impairment (MCI) Impaired cognitive function in one or more domains Milder than dementia, does not prevent independent functioning A noticeable change from previous levels of functioning MCI can be due to reversible causes such as Stress, anxiety or depression Physical illness such as thyroid problems Side-effects of medication However, 70% eventually get diagnosed with a dementia. Already, people aged 50+ represent 32% of working age population (ONS) Much neurodegenerative disease takes hold in mid-life, many years before any obvious symptoms. CANTAB Corporate Health All rights reserved Page 5
6 Cantab Mobile Memory and mood assessment for ages 50+ CANTAB Corporate Health All rights reserved Page 6
7 Usage in the NHS 400+ GP Surgeries Across 40 Healthcare Authorities 25,000+ cognitive assessments Detecting dementia earlier Saving NHS Time & Cost Memory impairment present in around 1 in 4 people Early access to support Most people reassured avoiding referrals and costs CANTAB Corporate Corporate Health Health All rights All reserved rights reserved Page 7
8 Benefits of early detection at work 3 out of 4 people would want to know if they were at risk of a neurological disorder GE Healthcare: The Value of Knowing. Millward Brown, 2014 Practical benefits Reduces risk to the business and the individual Enables proper and effective planning Reduces uncertainty and distress Lower diagnostic and treatment costs Improved effectiveness of treatments Timely advice and support CANTAB Corporate Health All rights reserved Page 8
9 CANTAB Insight 20-minute assessment for ages 18+ Paired Associates Learning (PAL) Spatial Working Memory (SWM) Matching to Sample (MTS) Depression Scale Total errors Total Errors Strategy Score Proportional Slowing % Correct Score Age, Education and Gender adjustment Episodic Memory Working Memory Executive Function Processing Speed Attention Mood CANTAB Corporate Health All rights reserved Page 9
10 Reporting 5 cognitive functions across 6 levels of performance, adjusted for age, sex and education level CANTAB Corporate Health All rights reserved Page 10
11 Common Causes of Cognitive Impairment Recreational substance abuse Depression, Anxiety, Stress Early AD 24% have hazardous patterns of drinking 6% alcohol dependence 3% drug dependence 1 Major depression: ~7% each year 2 Common mental disorder: 18% 3 43% of sick days due to stress 4 ½ of people over 60 are in early stages of AD but less than ½ will ever reach dementia 5 Memory, New learning Executive function, attention, memory some improvement with treatment Learning and memory, impulse control and decision-making 1. Royal College of Psychiatrists Position statement PS4/ NIMH, USA 3. McManus S, Meltzer H, Brugha T, et al (2009) 4.HSE Work related Stress, Anxiety and Depression Statistics in Great Britain Mar et al (2015) Spanish data CANTAB Corporate Health All rights reserved Page 11
12 Total errors (SWM) Managing existing conditions aids cognition Improvements after 6-months of antidepressant treatment Improvements after 6-months of treatment for type 2 diabetes Duloxetine Escitalopram Pre-treatment Post-treatment Egerhazi et al., Neuropsych Hungar, 2013; see also Rock et al., Psych Med, 2013; Herrera-Guzman et al., Psych Res, 2010 Ryan et al (2006) CANTAB Corporate Health All rights reserved Page 12
13 Side effects of common drugs Effects of single-doses of medication in healthy volunteers. CANTAB Corporate Health All rights reserved Page 13
14 Physical & brain health are inextricably linked What Is Measured Can Be Managed CANTAB Corporate Health All rights reserved Page 14
15 Memory concerns are common but technology allows easy, accurate measurement CANTAB Corporate Health All rights reserved Page 15
16 Managing brain health better would have a huge impact on our workforce A small shift in mean substantially decreases the number of people who are cognitively impaired and increases those functioning at peak performance. CANTAB Corporate Health All rights reserved Page 16
17 Makes Sense. CANTAB Corporate Health All rights reserved
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