Pathology of Testicular and Penile Neoplasms
|
|
- Clement Lawson
- 6 years ago
- Views:
Transcription
1 Pathology of Testicular and Penile Neoplasms
2
3 Maurizio Colecchia Editor Pathology of Testicular and Penile Neoplasms
4 Editor Maurizio Colecchia Department of Pathology Fondazione IRCCS Istituto dei Tumor Milan, Italy ISBN DOI / ISBN (ebook) Library of Congress Control Number: Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
5 To Mariangela and Matteo for their patient, silent, and loving support and to my parents
6
7 Preface As editor of Pathology of Testicular and Penile Neoplasms, I would like to briefly explain the inspiration for this book, which came from a sentence I read in the Treasure Gallery of the British Library: Science depends on the accurate observation, collection and recording of information. This sentence (attributed to Galileo, the father of scientific observation) is the leitmotif in this book on penile and testicular neoplasms rare tumors which are, however, increasing in frequency and whose epidemiological implications will be illustrated here in light of the most recent knowledge in the field. Congenital testicular lesions, impaired spermatogenesis, cryptorchidism, Klinefelter syndrome, testicular dysgenesis, entities contributing to infertility and their correlation with an increased risk of cancer, and childhood and prepubertal germ cell tumors will be discussed. The book will also describe the precursor lesions of invasive cancer as well as the staging criteria that provide the clinician with information for the correct treatment of metastatic disease. Furthermore, with the aid of summary tables, it will illustrate the main differential diagnoses between morphological entities. One chapter will be dedicated to the use of intraoperative frozen section analysis, which is increasingly being requested for the diagnosis of ultrasound-detected small testicular lesions. As a practical handbook for pathologists, this volume will be an aid to the diagnosis of these uncommon tumors and to dealing with the diagnostic pitfalls they often present. The text will provide updates on the new editions of the classification systems for testicular and penile tumors, with a view to achieving the necessary clarity in the terminology used by the pathologist in communicating diagnostic information. It aims to familiarize also less experienced pathologists with the sampling methods for orchiectomy and penectomy specimens and with the appropriate recording of pathology findings according to the guidelines approved by the International Society of Urological Pathology (ISUP). The book is designed to provide practitioners with the tools and knowledge to formulate a complete histopathology report with all the necessary information for the clinician. Its contents reflect the experience of the authors of the various chapters (11 on testicular cancer, 3 on cancer of the penis) in light of the recent literature, documented by more than 250 photographs; we have scrutinized the currently available information in an attempt to provide valuable updates on the variants of penile carcinoma, HPV-related and unrelated penile tumors, and newly classified testicular neoplasms. The images have not been published before, and I am deeply vii
8 viii Preface grateful to the authors and coauthors of Pathology of Testicular and Penile Neoplasms, who have contributed their personal cases, giving their time and energy to the drafting of the chapters of this book, which I hope you will enjoy reading. Milan, Italy Maurizio Colecchia
9 Acknowledgements Many people have helped me get this book into shape. The contributions of Alessia Bertolotti, PhD, in all stages of its development and in the technical preparation of the slides (recutting, immunohistochemical staining, scanning of interesting cases) were irreplaceable. Biagio Paolini, MD, has improved the photomicrographs through refined color enhancement. His efforts in standardizing the appearance of the illustrations will surely be appreciated by our readers. I also gratefully acknowledge the work of Alessio Pellegrinelli, MD, who has shown surprising versatility in designing tables and drawing illustrations to make the macroscopic images of Chap. 13 easier to understand. I thank Drs Bandieramonte, Torelli, and Catanzaro for having contributed with the macroscopic images of penile lesions from their clinical activity. Special thanks go to Marije de Jager for meticulously correcting the manuscript. I am particularly grateful for her help in uniforming the style across chapters. Thanks go as well to Paolo Castioni and Maria Morelli, who have enthusiastically contributed to this book in various ways. I express my heartfelt appreciation to the library staff of Fondazione IRCCS Istituto Nazionale dei Tumori and in particular to Rossella Ballarini. Finally, I gratefully remember the teachings of Professor Juan Rosai (hoping they shaped me) that directed me and many other pathologists to a methodical approach in diagnostic pathology. Maurizio Colecchia ix
10
11 Contents Part I Testicular Tumors: Epidemiology 1 Epidemiology of Testicular Cancer Gemma Gatta and Annalisa Trama Part II Tumors of the Testis and Paratesticular Structures 2 Congenital Lesions Manuel Nistal and Pilar González-Peramato 3 Entities Contributing to Infertility and Their Relationship to Oncogenic Risk Manuel Nistal and Pilar González-Peramato 4 Germ Cell Tumors of Infancy and Childhood Manuel Nistal and Pilar González-Peramato 5 The Stem Cell Origin and Pathogenetic Routes of Testicular Germ Cell Tumors Maurizio Colecchia, Alessia Bertolotti, Biagio Paolini, and Gregor Mikuz 6 Tumors of the Testis Gregor Mikuz and Maurizio Colecchia 7 Prognostic and Predictive Factors in Pathology of the Testis Nicola Nicolai 8 Handling of the Surgical Specimen and Pathology Reporting of Malignant Germ Cell and Sex Cord-Stromal Tumors of the Testis Marina Scarpelli, Roberta Mazzucchelli, Matteo Santoni, Valeria Sotte, Alessandro Conti, Antonio Lopez-Beltran, Liang Cheng, and Rodolfo Montironi 9 Cysts and Epithelial Proliferations of the Testicular Collecting System Antonio Lopez-Beltran, Rita Canas-Marques, Maria R. Raspollini, Rodolfo Montironi, Marina Scarpelli, and Liang Cheng xi
12 xii Contents 10 Paratesticular Soft Tissue Neoplasms Alessandro Franchi, Raffaella Santi, and Gabriella Nesi 11 Frozen Section in Testicular Pathology Maurizio Colecchia and Nicola Nicolai Part III Pathology of Precancerous Lesions and Tumors of the Penis 12 Precancerous Lesions of the Penis Maurizio Colecchia and Biagio Paolini 13 Tumors of the Penis and Scrotum Maurizio Colecchia, Alessia Bertolotti, Biagio Paolini, and Roberto Salvioni 14 Handling of the Surgical Specimen and Pathology Reporting of Penile Neoplasms Rodolfo Montironi, Roberta Mazzucchelli, Matteo Santoni, Valeria Sotte, Antonio Lopez-Beltran, Liang Cheng, and Marina Scarpelli Index
13 Contributors Alessia Bertolotti Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy Rita Canas-Marques Serviço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal Liang Cheng Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA Maurizio Colecchia Uropathology Unit, Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy Alessandro Conti Department of Odontostomatologic and Specialized Clinical Sciences, Section of Urology, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy Alessandro Franchi Division of Pathological Anatomy, University of Florence, Florence, Italy Gemma Gatta Evaluative Epidemiology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy Pilar González-Peramato Department of Pathology, Autonoma University of Madrid, Hospital Univ. La Paz., Madrid, Spain Antonio Lopez-Beltran Department of Pathology and Surgery, Faculty of Medicine, University of Cordoba, Cordoba, Spain Roberta Mazzucchelli Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy Gregor Mikuz Institute of Pathology, Medical University of Innsbruck, Innsbruck, Austria Rodolfo Montironi Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy Gabriella Nesi Division of Pathological Anatomy, University of Florence, Florence, Italy Nicola Nicolai Testis Surgery Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy xiii
14 xiv Contributors Manuel Nistal Department of Anatomy, Histology and Neuroscience, Autonoma University of Madrid, Madrid, Spain Biagio Paolini Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy Maria R. Raspollini Division of Histology and Molecular Diagnostics, University Hospital Careggi, University of Florence, Florence, Italy Roberto Salvioni Urology Unit, Fondazione IRCCS Istituto dei Tumori di Milano, Milan, Italy Raffaella Santi Division of Pathological Anatomy, University of Florence, Florence, Italy Matteo Santoni Medical Oncology, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy Marina Scarpelli Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy Valeria Sotte Medical Oncology, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy Annalisa Trama Evaluative Epidemiology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy
Pathology of Testicular and Penile Neoplasms. Maurizio Colecchia Editor
Pathology of Testicular and Penile Neoplasms Maurizio Colecchia Editor 123 Pathology of Testicular and Penile Neoplasms Maurizio Colecchia Editor Pathology of Testicular and Penile Neoplasms Editor Maurizio
More informationSami Shousha Editor. Breast Pathology. Problematic Issues
Breast Pathology Editor Breast Pathology Problematic Issues Editor Charing Cross Hospital Imperial College Healthcare NHS Trust & Imperial College London United Kingdom ISBN 978-3-319-28653-2 ISBN 978-3-319-28655-6
More informationPractical Case Studies in Hypertension Management. Series editor: Giuliano Tocci Rome Italy
Practical Case Studies in Hypertension Management Series editor: Giuliano Tocci Rome Italy The aim of the book series Practical Case Studies in Hypertension Management is to provide physicians who treat
More informationCongenital Hip Disease in Adults
Congenital Hip Disease in Adults George Hartofilakidis George C. Babis Kalliopi Lampropoulou-Adamidou Congenital Hip Disease in Adults George Hartofilakidis, MD, FACS Orthopaedic Department Medical School
More informationLouise Grech Alan Lau Editors. Pharmaceutical Care Issues of Patients with Rheumatoid Arthritis. From Hospital to Community
Louise Grech Alan Lau Editors Pharmaceutical Care Issues of Patients with Rheumatoid Arthritis From Hospital to Community Pharmaceutical Care Issues of Patients with Rheumatoid Arthritis Louise Grech
More informationEsthetic and Functional Management of Diastema
Esthetic and Functional Management of Diastema Ugur Erdemir Esra Yildiz Editors Esthetic and Functional Management of Diastema A Multidisciplinary Approach Editors Ugur Erdemir Faculty of Dentistry University
More informationPractical Case Studies in Hypertension Management. Series editor Giuliano Tocci Rome, Italy
Practical Case Studies in Hypertension Management Series editor Giuliano Tocci Rome, Italy The aim of the book series Practical Case Studies in Hypertension Management is to provide physicians who treat
More informationSurgical Techniques for Kidney Cancer
Surgical Techniques for Kidney Cancer Rakesh V. Khanna Gennady Bratslavsky Robert J. Stein Editors Surgical Techniques for Kidney Cancer 123 Editors Rakesh V. Khanna Department of Urology SUNY Upstate
More informationPharmaceutical Care Issues of Patients with Rheumatoid Arthritis
Pharmaceutical Care Issues of Patients with Rheumatoid Arthritis Louise Grech Alan Lau Editors Pharmaceutical Care Issues of Patients with Rheumatoid Arthritis From Hospital to Community Editors Louise
More informationReconstructive Oral and Maxillofacial Surgery
Reconstructive Oral and Maxillofacial Surgery Carlos Navarro Vila Editor Reconstructive Oral and Maxillofacial Surgery Editor Carlos Navarro Vila Hospital General Universitario Gregorio Marañón Madrid
More informationIn Clinical Practice
In Clinical Practice Taking a practical approach to clinical medicine, this series of smaller reference books is designed for the trainee physician, primary care physician, nurse practitioner and other
More informationAdvances in Experimental Medicine and Biology
Advances in Experimental Medicine and Biology Volume 938 Editorial Board IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel N.S. ABEL LAJTHA, Kline Institute for Psychiatric Research, Orangeburg,
More informationUrinary Tract Infection
Urinary Tract Infection Abhay Rané Ranan Dasgupta Editors Urinary Tract Infection Clinical Perspectives on Urinary Tract Infection Editors Abhay Rané, MS, FRCS, FRCS (Urol) Department of Urology Surrey
More informationAtlas of Lymph Node Anatomy
Atlas of Lymph Node Anatomy Mukesh G. Harisinghani Editor Atlas of Lymph Node Anatomy This publication was developed through an unrestricted educational grant from Siemens. Editor Mukesh G. Harisinghani
More informationMeasures of Positive Psychology
Measures of Positive Psychology Kamlesh Singh Mohita Junnarkar Jasleen Kaur Measures of Positive Psychology Development and Validation 123 Kamlesh Singh Department of Humanities and Social Sciences Indian
More informationSpringerBriefs in Applied Sciences and Technology
SpringerBriefs in Applied Sciences and Technology Computational Intelligence Series Editor Janusz Kacprzyk, Systems Research Institute, Polish Academy of Sciences, Warsaw, Poland SpringerBriefs in Computational
More informationWhite Coat Hypertension
White Coat Hypertension Giuseppe Mancia Guido Grassi Gianfranco Parati Alberto Zanchetti White Coat Hypertension An Unresolved Diagnostic and Therapeutic Problem Giuseppe Mancia Emeritus Professor University
More informationIatrogenic Effects of Orthodontic Treatment
Iatrogenic Effects of Orthodontic Treatment Roberto Justus Iatrogenic Effects of Orthodontic Treatment Decision-Making in Prevention, Diagnosis, and Treatment Roberto Justus Department of Orthodontics
More informationRadiation Therapy for Skin Cancer
Radiation Therapy for Skin Cancer Armand B. Cognetta Jr. William M. Mendenhall Editors Radiation Therapy for Skin Cancer Editors Armand B. Cognetta Jr. Dermatology Associates of Tallahassee Chief, Division
More informationPractical Issues in Geriatrics. Series Editor Stefania Maggi Aging Branch CNR-Neuroscience Institute Padova, Italy
Practical Issues in Geriatrics Series Editor Stefania Maggi Aging Branch CNR-Neuroscience Institute Padova, Italy This practically oriented series presents state of the art knowledge on the principal diseases
More informationSpringerBriefs in Criminology
SpringerBriefs in Criminology Policing Series editor M.R. Haberfeld City University of New York John Jay College of Criminal Justice New York, NY, USA More information about this series at http://www.springer.com/series/11179
More informationDesmond P. Kidd. Neuro-Ophthalmology. Illustrated Case Studies
Neuro-Ophthalmology Desmond P. Kidd Neuro-Ophthalmology Illustrated Case Studies Desmond P. Kidd Department of Clinical Neurosciences Royal Free Hospital London UK ISBN 978-1-4471-2409-2 DOI 10.1007/978-1-4471-2410-8
More informationHandbook of Insulin Therapies
Handbook of Insulin Therapies Winston Crasto Janet Jarvis Melanie J. Davies Handbook of Insulin Therapies Winston Crasto George Eliot Hospital NHS Trust, Nuneaton United Kingdom Janet Jarvis Leicester
More informationRadiology Illustrated
Radiology Illustrated For further volumes: http://www.springer.com/series/11755 In-One Kim Editor Radiology Illustrated: Pediatric Radiology Editor In-One Kim, M.D. Department of Radiology Seoul National
More informationClinician s Manual on Restless Legs Syndrome
Clinician s Manual on Restless Legs Syndrome Mark J. Buchfuhrer Clinician s Manual on Restless Legs Syndrome Second Edition Mark J. Buchfuhrer PIH Health Hospital - Downey Downey, CA USA ISBN 978-3-319-31372-6
More informationDifferential Diagnosis of Movement Disorders in Clinical Practice
Differential Diagnosis of Movement Disorders in Clinical Practice Abdul Qayyum Rana Peter Hedera Differential Diagnosis of Movement Disorders in Clinical Practice Abdul Qayyum Rana Parkinson's Clinic
More informationImaging of Urinary Tract Diverticula
Imaging of Urinary Tract Diverticula Vladimir M. Builov Imaging of Urinary Tract Diverticula Vladimir M. Builov Department of X-Ray and MRI RailWay Clinical Hospital Yaroslavl Russia ISBN 978-3-319-05382-0
More informationSPRINGER BRIEFS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. Gerhard Bauer Joseph S. Anderson. Gene Therapy for HIV From Inception to a Possible Cure
SPRINGER BRIEFS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY Gerhard Bauer Joseph S. Anderson Gene Therapy for HIV From Inception to a Possible Cure 123 SpringerBriefs in Biochemistry and Molecular Biology For
More informationEvidence-Based Forensic Dentistry
Evidence-Based Forensic Dentistry Balwant Rai Jasdeep Kaur Evidence-Based Forensic Dentistry Authors Balwant Rai Earth and Life Sciences Vrije Universiteit Amsterdam and ILEWG Amsterdam The Netherlands
More informationThe Cleveland Clinic Manual of Dynamic Endocrine Testing
The Manual of Dynamic Endocrine Testing Ahmet Bahadir Ergin A. Laurence Kennedy Manjula K. Gupta Amir H. Hamrahian The Manual of Dynamic Endocrine Testing Ahmet Bahadir Ergin Department of Endocrinology,
More informationGenetic Influences on Response to Drug Treatment for Major Psychiatric Disorders
Genetic Influences on Response to Drug Treatment for Major Psychiatric Disorders Janusz K. Rybakowski Alessandro Serretti Editors Genetic Influences on Response to Drug Treatment for Major Psychiatric
More informationHandbook for Venous Thromboembolism
Handbook for Venous Thromboembolism Gregory Piazza Benjamin Hohlfelder Samuel Z. Goldhaber Handbook for Venous Thromboembolism Gregory Piazza Cardiovascular Division Harvard Medical School Brigham and
More informationMedical and Surgical Complications of Sickle Cell Anemia
Medical and Surgical Complications of Sickle Cell Anemia Ahmed Al-Salem Medical and Surgical Complications of Sickle Cell Anemia Ahmed Al-Salem Department of Surgery Dar A lalafia Medical Company Qatif
More informationAlexander N. Sencha Elena V. Evseeva Mikhail S. Mogutov Yury N. Patrunov. Breast Ultrasound
Breast Ultrasound Alexander N. Sencha Elena V. Evseeva Mikhail S. Mogutov Yury N. Patrunov Breast Ultrasound Alexander N. Sencha Department of Ultrasound Diagnostics Yaroslavl Railway Clinic Yaroslavl
More informationRespiratory Medicine Series Editor: Sharon I.S. Rounds. Marc A. Judson Editor. Pulmonary Sarcoidosis A Guide for the Practicing Clinician
Respiratory Medicine Series Editor: Sharon I.S. Rounds Marc A. Judson Editor Pulmonary Sarcoidosis A Guide for the Practicing Clinician Respiratory Medicine Series Editor: Sharon I.S. Rounds For further
More informationAbnormal Female Puberty
Abnormal Female Puberty Heather L. Appelbaum Editor Abnormal Female Puberty A Clinical Casebook Editor Heather L. Appelbaum, MD Department of Obstetrics and Gynecology Hofstra Northwell School of Medicine
More informationRadiation Therapy for Extranodal Lymphomas
Radiation Therapy for Extranodal Lymphomas Keisuke Sasai Masahiko Oguchi Editors Radiation Therapy for Extranodal Lymphomas Editors Keisuke Sasai Department of Radiation Oncology Juntendo University Faculty
More informationEssentials in Ophthalmology
Essentials in Ophthalmology Series Editor Arun D. Singh, MD More information about this series at http://www.springer.com/series/5332 Kathryn Colby Editor Corneal Diseases in Children Challenges and Controversies
More informationLocal Flaps in Facial Reconstruction
Local Flaps in Facial Reconstruction Velupillai Ilankovan Madan Ethunandan Tian Ee Seah Local Flaps in Facial Reconstruction A Defect Based Approach Velupillai Ilankovan Poole Hospital NHS Foundation
More informationFrozen Section Library Series Editor Philip T. Cagle, MD Houston, Texas, USA
Frozen Section Library Series Editor Philip T. Cagle, MD Houston, Texas, USA For further volumes, go to http://www.springer.com/series/7869 Frozen Section Library: Central Nervous System Richard A. Prayson
More informationProgressive Multiple Sclerosis
Progressive Multiple Sclerosis Alastair Wilkins Editor Progressive Multiple Sclerosis Editor Alastair Wilkins, M.A., M.B., B.Chir, Ph.D., FRCP Department of Neurology Frenchay Hospital Bristol UK ISBN
More informationCognitive, Conative and Behavioral Neurology
Cognitive, Conative and Behavioral Neurology Michael Hoffmann Cognitive, Conative and Behavioral Neurology An Evolutionary Perspective Michael Hoffmann MD, PhD Professor of Neurology Orlando VA Medical
More informationEpigenetic Advancements in Cancer
Epigenetic Advancements in Cancer Manoj K. Mishra Kumar S. Bishnupuri Editors Epigenetic Advancements in Cancer Editors Manoj K. Mishra Department of Biological Sciences Alabama State University Montgomery,
More informationRadiation Therapy for Gastrointestinal Cancers
Radiation Therapy for Gastrointestinal Cancers Theodore Hong Prajnan Das Editors Radiation Therapy for Gastrointestinal Cancers Editors Theodore Hong Massachusetts General Hospital Harvard Medical School
More informationJohn Papadopoulos David R. Schwartz Consulting Editor. Pocket Guide to Critical Care Pharmacotherapy Second Edition
John Papadopoulos David R. Schwartz Consulting Editor Pocket Guide to Critical Care Pharmacotherapy Second Edition 123 Pocket Guide to Critical Care Pharmacotherapy John Papadopoulos Author David R. Schwartz
More informationMorphological Aspects of Inner Ear Disease
Morphological Aspects of Inner Ear Disease Yasuya Nomura Morphological Aspects of Inner Ear Disease Yasuya Nomura President The Society for Promotion of International Oto-Rhino-Laryngology Tokyo, Japan
More informationPediatric Endodontics
Pediatric Endodontics Anna B. Fuks Benjamin Peretz Editors Pediatric Endodontics Current Concepts in Pulp Therapy for Primary and Young Permanent Teeth Editors Anna B. Fuks Department of Pediatric Dentistry
More informationDepression and Anxiety in Patients with Chronic Respiratory Diseases
Depression and Anxiety in Patients with Chronic Respiratory Diseases Amir Sharafkhaneh Abebaw Mengistu Yohannes Nicola Alexander Hanania Mark E. Kunik Editors Depression and Anxiety in Patients with Chronic
More informationThe Many Faces of Social Attention
The Many Faces of Social Attention Aina Puce Bennett I. Bertenthal Editors The Many Faces of Social Attention Behavioral and Neural Measures 1 3 Editors Aina Puce Psychological and Brain Sciences Indiana
More informationRadiation Therapy for Head and Neck Cancers
Radiation Therapy for Head and Neck Cancers Murat Beyzadeoglu Gokhan Ozyigit Ugur Selek Editors Radiation Therapy for Head and Neck Cancers A Case-Based Review Editors Murat Beyzadeoglu, MD Professor
More informationNeurobiological Bases of Abnormal Aggression and Violent Behaviour
Neurobiological Bases of Abnormal Aggression and Violent Behaviour . József Haller Neurobiological Bases of Abnormal Aggression and Violent Behaviour József Haller Department of Behavioral Neurobiology
More informationBreast Cancer, Fertility Preservation and Reproduction. Nicoletta Biglia Fedro Alessandro Peccatori Editors
Breast Cancer, Fertility Preservation and Reproduction Nicoletta Biglia Fedro Alessandro Peccatori Editors 123 Breast Cancer, Fertility Preservation and Reproduction Nicoletta Biglia Fedro Alessandro
More informationAtlas of Lymphatic Anatomy in the Head, Neck, Chest and Limbs
Atlas of Lymphatic Anatomy in the Head, Neck, Chest and Limbs Wei-Ren Pan Atlas of Lymphatic Anatomy in the Head, Neck, Chest and Limbs Wei-Ren Pan Department of Anatomy Xuzhou Medical College Xuzhou Jiangsu
More informationTherapeutic rtms in Neurology
Therapeutic rtms in Neurology Thomas Platz Editor Therapeutic rtms in Neurology Principles, Evidence, and Practice Recommendations Editor Thomas Platz BDH-Klinik Greifswald Ernst-Moritz-Arndt Universität
More informationHealth Issues in Women with Multiple Sclerosis
Health Issues in Women with Multiple Sclerosis Maria K. Houtchens A. Dessa Sadovnick Editors Health Issues in Women with Multiple Sclerosis Editors Maria K. Houtchens Partners MS Center Brigham and Women
More informationSinus Headache, Migraine, and the Otolaryngologist
Sinus Headache, Migraine, and the Otolaryngologist Mark E. Mehle Editor Sinus Headache, Migraine, and the Otolaryngologist A Comprehensive Clinical Guide 123 Editor Mark E. Mehle Private Practice ENT and
More informationRecurrent Erosion Syndrome and Epithelial Edema
Recurrent Erosion Syndrome and Epithelial Edema Helena M. Tabery Recurrent Erosion Syndrome and Epithelial Edema In Vivo Morphology in the Human Cornea Helena M. Tabery, MD Malmö Sweden helena.tabery@telia.com
More informationLow and Lower Fertility
Low and Lower Fertility Ronald R. Rindfuss Minja Kim Choe Editors Low and Lower Fertility Variations across Developed Countries Editors Ronald R. Rindfuss Department of Sociology and Carolina Population
More informationSpringerBriefs in Cancer Research
SpringerBriefs in Cancer Research For further volumes: http://www.springer.com/series/10786 Natalia Aptsiauri Angel Miguel Garcia-Lora Teresa Cabrera MHC Class I Antigens In Malignant Cells Immune Escape
More informationErin Lawson Mark S. Wallace Editors. Fibromyalgia. Clinical Guidelines and Treatments
Fibromyalgia Erin Lawson Mark S. Wallace Editors Fibromyalgia Clinical Guidelines and Treatments Editors Erin Lawson, MD Voluntary Faculty Department of Anesthesiology Center for Pain Medicine University
More informationMusculoskeletal Health in Women
Musculoskeletal Health in Women Elinor Mody Elizabeth Matzkin Editors Musculoskeletal Health in Women Editors Elinor Mody, MD Department of Rheumatology Gretchen and Edward Fish Center for Women s Health
More informationPolymyalgia Rheumatica and Giant Cell Arteritis
Polymyalgia Rheumatica and Giant Cell Arteritis Jozef Rovenský Burkhard Leeb Viera Štvrtinová Richard Imrich Editors Polymyalgia Rheumatica and Giant Cell Arteritis Third Edition Editors Josef Rovenský
More informationWound Management in Urgent Care
Wound Management in Urgent Care Brittany Busse Wound Management in Urgent Care Brittany Busse, MD Med 7 Urgent Care Folsom, CA, USA ISBN 978-3-319-27426-3 DOI 10.1007/978-3-319-27428-7 ISBN 978-3-319-27428-7
More informationCLINICAL GASTROENTEROLOGY
CLINICAL GASTROENTEROLOGY Series Editor George Y. Wu University of Connecticut Health Center, Farmington, CT, USA For further volumes: http://www.springer.com/series/7672 Elizabeth J. Carey Keith D. Lindor
More informationProgress in Social Psychiatry in Japan
Progress in Social Psychiatry in Japan Yoshibumi Nakane Progress in Social Psychiatry in Japan An Approach to Psychiatric Epidemiology Yoshibumi Nakane Department of Neuropsychiatry Nagasaki University
More informationGynecologic Oncology
Gynecologic Oncology Ramez N. Eskander Robert E. Bristow Editors Gynecologic Oncology A Pocketbook Editors Ramez N. Eskander, M.D. Assistant Professor Division of Gynecologic Oncology Department of Obstetrics
More informationHeadache. Series editors Paolo Martelletti Roma, Italy Rigmor Jensen Glostrup, Denmark
Headache Series editors Paolo Martelletti Roma, Italy Rigmor Jensen Glostrup, Denmark The huge importance of headache in public health arises from its causal association with personal and societal burdens
More informationDonald E. Wesson. Editor. Metabolic Acidosis. A Guide to Clinical Assessment and Management
Metabolic Acidosis Donald E. Wesson Editor Metabolic Acidosis A Guide to Clinical Assessment and Management Editor Donald E. Wesson, MD, MBA Baylor Scott and White Health Department of Internal Medicine
More informationComplications of Anorectal Surgery
Complications of Anorectal Surgery Herand Abcarian Jose Cintron Editors Complications of Anorectal Surgery Prevention and Management 123 Editors Herand Abcarian Division of Colon and Rectal Surgery University
More informationIndirect Questioning in Sample Surveys
Indirect Questioning in Sample Surveys Arijit Chaudhuri Tasos C. Christofides Indirect Questioning in Sample Surveys 123 Arijit Chaudhuri Applied Statistics Unit Indian Statistical Institute Kolkata,
More informationNext Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders
Next Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders Lee-Jun C. Wong Editor Next Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders
More informationTadaaki Kirita Ken Omura Editors. Oral Cancer. Diagnosis and Therapy
Oral Cancer Tadaaki Kirita Ken Omura Editors Oral Cancer Diagnosis and Therapy Editors Tadaaki Kirita Department of Oral and Maxillofacial Surgery Nara Medical University Nara, Japan Ken Omura Oral Cancer
More informationSocial Control of Sex Offenders
Social Control of Sex Offenders D. Richard Laws Social Control of Sex Offenders A Cultural History D. Richard Laws Pacific Behavioural Assessment Victoria, British Columbia, Canada ISBN 978-1-137-39125-4
More informationOsteoarthritic Knee Joint Painted by Artist: Mika Katsuta (Japan)
Osteoarthritis Osteoarthritic Knee Joint Painted by Artist: Mika Katsuta (Japan) Mohit Kapoor Nizar N. Mahomed Editors Osteoarthritis Pathogenesis, Diagnosis, Available Treatments, Drug Safety, Regenerative
More informationApplications. in Oncology
Kewal K. Jain Applications of Biotechnology in Oncology Applications of Biotechnology in Oncology Applications of Biotechnology in Oncology Kewal K. Jain, MD, FRACS, FFPM Jain PharmaBiotech, Basel, Switzerland
More informationEmergency Department Management of Obstetric Complications
Emergency Department Management of Obstetric Complications Joelle Borhart Editor Emergency Department Management of Obstetric Complications Editor Joelle Borhart MedStar Georgetown University Hospital
More informationImaging of Alimentary Tract Perforation
Imaging of Alimentary Tract Perforation Luigia Romano Antonio Pinto Editors Imaging of Alimentary Tract Perforation Editors Luigia Romano Department of Radiology A. Cardarelli Hospital Naples Italy Antonio
More informationSpringerBriefs in Psychology. Series Editors Daniel David Raymond A. DiGiuseppe Kristene A. Doyle
SpringerBriefs in Psychology Series Editors Daniel David Raymond A. DiGiuseppe Kristene A. Doyle Epidemiological studies show that the prevalence of mental disorders is extremely high across the globe
More informationInflammation and Lung Cancer
Inflammation and Lung Cancer Steven M. Dubinett Editor Inflammation and Lung Cancer 1 3 Editor Steven M. Dubinett David Geffen School of Medicine at UCLA Los Angeles California USA ISBN 978-1-4939-2723-4
More informationPATHOLOGY OF MALIGNANT MELANOMA
PATHOLOGY OF MALIGNANT MELANOMA Springer Science+Business Media, LLC PATHOLOGY of MALIGNANT MELANOMA Raymond L. Barnhill, MD Professor of Dermatology and Pathology, Departments of Dermatology and Pathology,
More informationFrozen Section Library: Lung
Frozen Section Library: Lung FROZEN SECTION LIBRARY SERIES Philip T. Cagle, MD, Series Editor 1. Timothy Craig Allen, Philip T. Cagle: Frozen Section Library: Lung 2009 ISBN 978-0-387-09572-1 Frozen Section
More informationThe Role of Bacteria in Urology
The Role of Bacteria in Urology Dirk Lange Ben Chew Editors The Role of Bacteria in Urology Editors Dirk Lange Basic Science Research The Stone Centre at Vancouver General Hospital Vancouver British Columbia
More informationAbsolute Neurocritical Care Review
Absolute Neurocritical Care Review Zachary David Levy Editor Absolute Neurocritical Care Review Editor Zachary David Levy Assistant Professor of Emergency Medicine and Neurosurgery Hofstra Northwell School
More informationPediatric Lens Diseases
Pediatric Lens Diseases Yizhi Liu Editor Pediatric Lens Diseases Editor Yizhi Liu State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Guangzhou, Guangdong, China ISBN 978-981-10-2626-3 ISBN
More informationMorbid Obesity in Adolescents
Morbid Obesity in Adolescents ThiS is a FM Blank Page Kurt Widhalm Gerhard Prager Editors Morbid Obesity in Adolescents Conservative Treatment and Surgical Approaches Editors Kurt Widhalm Department of
More informationCerebral Blood Flow, Metabolism, and Head Trauma
Cerebral Blood Flow, Metabolism, and Head Trauma Christian W. Kreipke Editors Jose A. Rafols Cerebral Blood Flow, Metabolism, and Head Trauma The Pathotrajectory of Traumatic Brain Injury Editors Christian
More informationMark W.J. Strachan Brian M. Frier. Insulin Therapy. A Pocket Guide
Insulin Therapy Mark W.J. Strachan Brian M. Frier Insulin Therapy A Pocket Guide Mark W.J. Strachan, MD, FRCP (Ed) Metabolic Unit Western General Hospital Edinburgh United Kingdom Brian M. Frier, MD,
More informationBasics of Oncology. Second Edition Frederick O. Stephens Karl Reinhard Aigner
Basics of Oncology Second Edition Frederick O. Stephens Karl Reinhard Aigner 123 Basics of Oncology Frederick O. Stephens Karl Reinhard Aigner Basics of Oncology Second Edition With Contribution by Kornelia
More informationECG INTERPRETATION: FROM PATHOPHYSIOLOGY TO CLINICAL APPLICATION
ECG INTERPRETATION: FROM PATHOPHYSIOLOGY TO CLINICAL APPLICATION ECG INTERPRETATION: FROM PATHOPHYSIOLOGY TO CLINICAL APPLICATION by Fred Kusumoto, MD Electrophysiology and Pacing Service Division of Cardiovascular
More informationDeep Brain Stimulation for Neurological Disorders
Deep Brain Stimulation for Neurological Disorders Toru I t a k u ra Editor Deep Brain Stimulation for Neurological Disorders Theoretical Background and Clinical Application Editor Toru Itakura, MD, PhD
More informationMinimally Invasive Gynecological Surgery
Minimally Invasive Gynecological Surgery O l av Is t re Editor Minimally Invasive Gynecological Surgery Editor Olav Istre, MD, PhD Fredriksberg Denmark ISBN 978-3-662-44058-2 ISBN 978-3-662-44059-9 (ebook)
More informationPlanning and Care for Children and Adolescents with Dental Enamel Defects
Planning and Care for Children and Adolescents with Dental Enamel Defects Etiology, Research and Contemporary Management Bernadette K. Drummond Nicola Kilpatrick Editors 123 Planning and Care for Children
More informationFrozen Section Library: Pleura
Frozen Section Library: Pleura For other titles published in this series, go to www.springer.com/series/7869 Frozen Section Library: Pleura Philip T. Cagle, MD Weill Medical College of Cornell University,
More informationMitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy
Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy Dhyan Chandra Editor Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy 1 3 Editor Dhyan Chandra, Associate
More informationPalgrave Advances in Behavioral Economics. Series Editor John F. Tomer Co-Editor, Jl of Socio-Economics Manhattan College Riverdale, USA
Palgrave Advances in Behavioral Economics Series Editor John F. Tomer Co-Editor, Jl of Socio-Economics Manhattan College Riverdale, USA This ground breaking series is designed to make available in book
More informationChromosomal Translocations and Genome Rearrangements in Cancer
Chromosomal Translocations and Genome Rearrangements in Cancer Janet D. Rowley Michelle M. Le Beau Terence H. Rabbitts Editors Chromosomal Translocations and Genome Rearrangements in Cancer Editors Janet
More informationMilind Desai Christine Jellis Teerapat Yingchoncharoen Editors. An Atlas of Mitral Valve Imaging
Milind Desai Editors An Atlas of Mitral Valve Imaging 123 An Atlas of Mitral Valve Imaging Milind Desai Editors An Atlas of Mitral Valve Imaging Editors Milind Desai Department of Cardiovascular Medicine
More informationAtlas of Peripheral Nerve Ultrasound
Atlas of Peripheral Nerve Ultrasound Siegfried Peer Hannes Gruber Editors Atlas of Peripheral Nerve Ultrasound With Anatomic and MRI Correlation Editors Siegfried Peer CTI GesmbH Klostergasse 4 Innsbruck
More informationPerineal Trauma at Childbirth
Perineal Trauma at Childbirth Khaled M.K. Ismail Editor Perineal Trauma at Childbirth Editor Khaled M.K. Ismail University of Birmingham Birmingham, United Kingdom ISBN 978-3-319-14859-5 DOI 10.1007/978-3-319-14860-1
More information