THINK LATERAL! VALOIS PHARMA SIDE ACTUATED NASAL SPRAY DEVICE. Teva Miami on Oct.1, /
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1 1 THINK LATERAL! VALOIS PHARMA SIDE ACTUATED NASAL SPRAY DEVICE Teva Miami on Oct.1, /
2 NASAL ALLERGY Rx MARKET : Trends 2 Mature market in developed countries Few NCEs = Value shift to the device Generics threat LCM Opportunity for new devices improving patient compliance and market differentiation SIDE ACTUATED NASAL SPRAY DEVICE Teva Miami on Oct.1, /
3 RESEARCH FINDINGS : The voice of the patient OVERALL RESEARCH FINDINGS Though patients are satisfied with their current samples Side Actuation provides a meaningful patient benefit In particular, lateral (vs front) side actuation EXPECTED FEATURES Gripping ease (#1 in importance) Force to actuate (#2 in importance) Definitive stroke: confidence that the right dose is dispensed (steroids) Fingers away from nostrils (ergonomics, hygiene) But not too far away (to keep an accurate control during spray delivery) Teva Miami on Oct.1, 2009 /
4 VALOIS PHARMA NOVEL DEVICE 4 91 Trigger Short Nozzle Protective cap + transportation safety See thru Window 26,5 47 Teva Miami on Oct.1, /
5 VALOIS NOVEL DEVICE KEY FEATURES 5 EASE OF USE Compact, Ergonomic, Intuitive design Soft actuation Level indicator windows PATIENT COMFORT Short and motionless nasal nozzle Fingers no longer in contact with nostrils PRODUCT DIFFERENTIATION Easy to customize Teva Miami on Oct.1, /
6 SECOND RESEARCH FINDINGS 6 Test performed in the UK 10 Nasal spray users (2IDIs + 4Dyads) 5 Physicians ( GPs + 2 ENTs IDIs) The objectives Make sure that Valois Pharma Novel Device is well accepted by patients and physicians Identify what are the advantages over the existing offer and whether there is a need for further improvement Assess different nozzle lengths Teva Miami on Oct.1, /
7 SECOND RESEARCH FINDINGS 7 The contenders The leading top actuated nasal sprayer and the only marketed side actuated nasal sprayer for Allergy drugs Valois Side actuated device with nozzle lengths Teva Miami on Oct.1, /
8 SECOND RESEARCH FINDINGS UK Physician Preference VALOIS Pharma Novel Device preferred amongst physicians, followed by Top actuated and Side actuated sprayer B; Before seeing alternative options, 4 of 5 physicians preferred VALOIS; after seeing longer nozzle options, all 5 preferred VALOIS as #1 Teva Miami on Oct.1, / 1 Nasonex Top VALOIS Ergo Avamys Side actuated actuated sprayer Like Best Like 2nd Best Like Least sprayer B 2 0
9 SECOND RESEARCH FINDINGS 9 PHYSICIANS : From those rating it #1: Easy to use leads to compliance Feels solid/well-made Comfortable feel in hand, easy location of digit on actuator Looks nice Nozzle must be appropriate size that will suit most people/ages Good for children (easy to press) Novelty factor Viewing window is an improvement Lid should be made easier to remove Drug delivered more effectively to site of action From those rating it #2: Small size of top actuated sprayer wins over Valois Pharma Novel Device (changed once new nozzles were presented) From those rating it #: (none rated as #) Teva Miami on Oct.1, /
10 SECOND RESEARCH FINDINGS 10 UK Patient Preference Top actuated sprayer VALOIS Like Best Like 2nd Best Like Least Side actuated sprayer B Valois Pharma Novel Device was rated as best or second best in 9 of 10 UK patients Teva Miami on Oct.1, /
11 SECOND RESEARCH FINDINGS 11 UK patient preference (before and after) Like Best Like Best (after) Top actuated VALOIS Side act B After exposing to alternative nozzles, Valois Pharma Novel Device was rated as Best by 6 patients and second best by 4 patients Teva Miami on Oct.1, /
12 SECOND RESEARCH FINDINGS 12 PATIENTS From those rating it #1 with modified nozzle: User-friendly, easy to grip Well-designed, functions well Like longer nozzle, can get higher up and be ensured it s working Design is compact and clean Nice size bottle, lid, nozzle length From those rating it #2 with modified nozzle: The longer nozzle makes the choice MUCH CLOSER, but still prefer top actuated sprayer Don t want something so space-age Lid is like a jigsaw puzzle Must switch hands to do other nostril, prefer top actuated sprayer From those rating it # with modified nozzle: (none) Teva Miami on Oct.1, /
13 1 CONCLUSIONS key characteristics identified in the 1st PAT are achieved : Good grip Force of actuation Definitive stroke In our test, Valois side actuated device was well accepted by patients and physicians and preferred to the existing offer Longer nozzle is a plus Test in the US to be performed to confirm UK results Teva Miami on Oct.1, /
14 14 THANK YOU! QUESTIONS? Welcome to our Booth E Teva Miami on Oct.1, /
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