Course Plan (Syllabus): Pharmacology I

Transcription

1 Course Plan (Syllabus): Pharmacology I (A) Course Identification and General Information Course Number & Code PHT 371 Course Title Pharmacology I Program (s) in which the course is offered B.Pharm.Sc. Credit Units 3 Units' Type Theo. Prac. Language of teaching the course 2 English 1 Study level/year at which this course is offered 5 th Pre requisite (if any) PHT 282 & PHSL 253 Location of teaching the course Co requisite (if any) (B) Course Description This course introduces the basic pharmacological principles applicable to all drugs including pharmacokinetics, pharmacodynamics and pharmacotherapeutics. It also covers the pharmacology of peripheral neurotransmitters, therapeutic uses and adverse effects of drugs acting on autonomic nervous system, both sympathetic and parasympathetic. Additionally, pharmacology of autacoids and their antagonists are discussed. (C) Course Objectives Upon successful completion of the course, the students will be able to: 1) Recognize the basic principles of pharmacokinetic and pharmacodynamicc properties of drugs. 2) Identify the drug groups affecting autonomic nervous system directly or indirectly, their therapeutic uses and adverse drug reactions. 3) Outline the basic principles of autacoids functions and therapeutic uses of their analogues and antagonists. 4) Investigate the effects of drugs on laboratory experimental animals.

2 (D) Course Items Distribution of Semester Weekly Plan of Course Items and Activities Theoretical Aspect : (Topics to be Covered) Order Topics List ,3 3 4, 5, , , ,15 Introduction to pharmacology. Pharmacokinetics: Route of drug administration. Pharmacokinetics: Drug absorption. Drug distribution. Drug metabolism. Drug excretion. Pharmacodynamics: Mechanism of drug actions. Receptor concept. Drug response curve. Adverse drug reactions. Drug interactions Introduction to Autonomic Nervous System. Cholinergic agonists. Cholinergic antagonists and neuromuscular blockers. Adrenergic agonists. Adrenergic antagonist. Autacoids.

3 Application part (Pra actical): (Topics to be Covered) Order Topics List Experimental animals and their handling Routes of administration Liver microsomal drug metabolizing enzymes Doseresponse curve Effect of cholinergic drugs on eye Effect of adrenergic drugs on eye Pharmacology of neuromuscular junctionn Effect of neuromuscular blockers Effect of drugs on isolated intestine Investigation of unknown drugs on isolated intestine Computer exercise program1: effect of autonomic drugs on blood pressure and heart. Computer exercise program 2: effect of autacoids agonists and antagonists on blood pressure and heart. Computer exercise program 3: Investigation of unknown drugs. Computer exercise program 4: Investigation of unknown drugs. Effects of different autonomic drugs on blood pressure and heart rate

4 (E) Schedule of Tasks for Students During the Semester Type of Tasks Mark Proportion of Final 1 Drills 2 Exercises & Home works 3 Project ( single\group) 4 Research 5 Essay/Report 6 Participation 7 Practical Tests 8 Oral Tests 9 Quizzes 10 Written Test (1) 11 Written Test (2) , , % 5% 15% 15% 12 Final Exam (practical) Final Exam (theoretical) 17, % 40% 14 Others

5 (F) Learning Resources Written in the following order: ( Author Year of publication Title Edition Place of publication Publisher) 1 Required Textbook(s) ( maximum two ). 1) Richard A. Harvey, and Pamela C. Champe (2009), Pharmacology (Lippincott's Illustrated Reviews) 4 th ed., Lippincott Williams& Wilkins. 2) B.G. Katzung (2008), Basic and Clinical Pharmacology, 12 th ed., New York, USA McGrawHill Medical. 2 Essential References. 1) Garge and Aryra (2005), Experimental pharmacology for undergraduatee students, Delhi, India, CBS Publisher & Distributors P Ltd. 3 Recommended Books and Reference Materials. 1) Laurence L. Brunton et al, (2006), Goodman & Gilman s The pharmacological basis of therapeutics, 11 th ed., New York, USA, McGrawHill. 2) Humphrey P. R., Maureen M. Dale, J M. Ritter, R Flower (2011), Rang & Dale s Pharmacology 7 th ed., London, UK, Churchilll Livingstone. 4 Electronic Materials and Web Sites etc. 1) 2) 3) 4) 5) Jusur system; elearning system in Taibah University ( 5 Other Learning Material (such 1) Video and computer based learning systems. h as computerbased programs/cd, professional standards/ regulations).