Feedback Education and Neuroscience. Pankaj Sah

Size: px
Start display at page:

Download "Feedback Education and Neuroscience. Pankaj Sah"

Transcription

1 Feedback Education and Neuroscience Pankaj Sah

2 Science of Learning Learning The process of acquiring a skill or knowledge that leads to a change in behaviour Memory The ability to retain and recover information from a previous experience Education Learning during which Skills/Knowledge/Ideas transferred from a teacher to student(s) Memory formation is an essential part of Education

3 Information/ skills Testing / Recall learning memory Storage 3

4 The feedback loop Teaching Testing 3 x 6 = 15 4 x 5 = 21 Feedback 4

5 What kind of feedback? Four general types recognised about the task processing the task self regulation person? What is the best way and how to decide? Why does it work?

6

7 Theories of mental function Rene Descartes the original dualist 1632, It is a problem of the mind, not the brain - a physical object Mental function results from Neural Activity

8 Neuron Hypothesis 1906 Camillo Golgi Santiago Ramon y Cajal

9 About neurons billion Connected in networks - an electrochemical machine

10 About neurons in human brain Connections are synapses Each cell has up to 10,000 connections Total number of connections is immense!

11 Neural circuits are electrochemical machines A 5 ms 50 mv Presynaptic B Postsynaptic

12 Cellular theories of learning and memory formation Cajal Changes in connection strength The organisation of behaviour Hebbian Synapse

13 Hebbian Synapses A B A B Cells that fire together wire together

14 The case of H.M. Henry Molaison 1953 Age 60, 1986 Died 2008 age 82 At age 9 H.M. was knocked down while riding a bicycle Sustained brain injury that led to severe epilepsy 1953 (age 26) - operated on and inner surface of temporal lobe removed including the hippocampus After surgery relieved seizures but left with severe memory loss Unable to form new memories though retained past memories

15 Tim Bliss and Terje Lomo describe synaptic plasticity in the hippocampus Synaptic strength % This is long -term potentiation (LTP) Acquired rapidly Long lasting

16 Brain Function Activity Circuits Behaviour

17 Fear conditioning! Before conditioning After conditioning Defense behavior - freezing CS no response CS Autonomic changes HR/BP defecation Hypothalamic/pituitary

18 CS+ CS- Conditioned response measure acquisition extinction No extinction Trial # Day 1 Day 2 Day 3 or Day 30

19 Auditory thalamus LA Somatosensory thalamus Auditory cortex BA Somatosensory cortex CEA Effector targets

20 stimulus amygdala CS response US

21 stimulus amygdala response

22 stimulus amygdala response

23 Cellular model for fear conditioning: Hebbian plasticity in the amygdala LA neurons! before! after! CS! epsp! US! output! CS! Synaptic strength % Time Learning LTP - Long term potentiation

24 Learning / Memory Education Brain + + Systems Networks Neurons Synapses Science of Learning Pedagogy Biological understanding of learning Molecules Neuroscience

25 Reconsolidation Memory Formation Short term Memory Formation Short term Consolidation Long term Consolidation Recall?Long term Recall1 Reconsolidation Recall2 Memory Memory

26 The testing effect Study Study Study Recall Study Study Study Recall Test

27

28 Partial reinforcement

29 unlearning?

30 Renew Reconsolidate Recall memor y -? Error Result

Neuronal Plasticity, Learning and Memory. David Keays Institute of Molecular Pathology

Neuronal Plasticity, Learning and Memory. David Keays Institute of Molecular Pathology Neuronal Plasticity, Learning and Memory David Keays Institute of Molecular Pathology http://keayslab.org Structure 1. What is learning and memory? 2. Anatomical basis 3. Cellular basis 4. Molecular

More information

Systems Neuroscience November 29, Memory

Systems Neuroscience November 29, Memory Systems Neuroscience November 29, 2016 Memory Gabriela Michel http: www.ini.unizh.ch/~kiper/system_neurosci.html Forms of memory Different types of learning & memory rely on different brain structures

More information

Behavioral Neuroscience: Fear thou not. Rony Paz

Behavioral Neuroscience: Fear thou not. Rony Paz Behavioral Neuroscience: Fear thou not Rony Paz Rony.paz@weizmann.ac.il Thoughts What is a reward? Learning is best motivated by threats to survival Threats are much better reinforcers Fear is a prime

More information

Behavioral Neuroscience: Fear thou not. Rony Paz

Behavioral Neuroscience: Fear thou not. Rony Paz Behavioral Neuroscience: Fear thou not Rony Paz Rony.paz@weizmann.ac.il Thoughts What is a reward? Learning is best motivated by threats to survival? Threats are much better reinforcers? Fear is a prime

More information

Why is dispersion of memory important*

Why is dispersion of memory important* What is memory* It is a web of connections Research has shown that people who lose their memory also lose the ability to connect things to each other in their mind It is these connections that let us understand

More information

Why do we have a hippocampus? Short-term memory and consolidation

Why do we have a hippocampus? Short-term memory and consolidation Why do we have a hippocampus? Short-term memory and consolidation So far we have talked about the hippocampus and: -coding of spatial locations in rats -declarative (explicit) memory -experimental evidence

More information

9.01 Introduction to Neuroscience Fall 2007

9.01 Introduction to Neuroscience Fall 2007 MIT OpenCourseWare http://ocw.mit.edu 9.01 Introduction to Neuroscience Fall 2007 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms. Declarative memory conscious,

More information

The Neurobiology of Learning and Memory

The Neurobiology of Learning and Memory The Neurobiology of Learning and Memory JERRY W. RUDY University of Colorado, Boulder Sinauer Associates, Inc. Publishers Sunderland, Massachusetts 01375 Table of Contents CHAPTER 1 Introduction: Fundamental

More information

Neuroscience with Pharmacology 2 Functions and Mechanisms of Reflexes. Prof Richard Ribchester

Neuroscience with Pharmacology 2 Functions and Mechanisms of Reflexes. Prof Richard Ribchester Neuroscience with Pharmacology 2 Functions and Mechanisms of Reflexes Prof Richard Ribchester René Descartes Cogito, ergo sum The 21st century still holds many challenges to Neuroscience and Pharmacology

More information

Introduction to Physiological Psychology Review

Introduction to Physiological Psychology Review Introduction to Physiological Psychology Review ksweeney@cogsci.ucsd.edu www.cogsci.ucsd.edu/~ksweeney/psy260.html n Learning and Memory n Human Communication n Emotion 1 What is memory? n Working Memory:

More information

Memory retention the synaptic stability versus plasticity dilemma

Memory retention the synaptic stability versus plasticity dilemma Memory retention the synaptic stability versus plasticity dilemma Paper: Abraham, Wickliffe C., and Anthony Robins. "Memory retention the synaptic stability versus plasticity dilemma." Trends in neurosciences

More information

Shift 1, 8 July 2018, 09:30-13:00

Shift 1, 8 July 2018, 09:30-13:00 Shift 1, 8 July 2018, 09:30-13:00 CNS patterning A001-A014 Stem cells: basic biology and postnatal neurogenesis - part I Development of neural systems: Molecular and genetic characterisationa Epigenetic

More information

Introduction to Physiological Psychology Learning and Memory II

Introduction to Physiological Psychology Learning and Memory II Introduction to Physiological Psychology Learning and Memory II ksweeney@cogsci.ucsd.edu cogsci.ucsd.edu/~ksweeney/psy260.html Memory Working Memory Long-term Memory Declarative Memory Procedural Memory

More information

The synaptic Basis for Learning and Memory: a Theoretical approach

The synaptic Basis for Learning and Memory: a Theoretical approach Theoretical Neuroscience II: Learning, Perception and Cognition The synaptic Basis for Learning and Memory: a Theoretical approach Harel Shouval Phone: 713-500-5708 Email: harel.shouval@uth.tmc.edu Course

More information

VS : Systemische Physiologie - Animalische Physiologie für Bioinformatiker. Neuronenmodelle III. Modelle synaptischer Kurz- und Langzeitplastizität

VS : Systemische Physiologie - Animalische Physiologie für Bioinformatiker. Neuronenmodelle III. Modelle synaptischer Kurz- und Langzeitplastizität Bachelor Program Bioinformatics, FU Berlin VS : Systemische Physiologie - Animalische Physiologie für Bioinformatiker Synaptische Übertragung Neuronenmodelle III Modelle synaptischer Kurz- und Langzeitplastizität

More information

Synap&c Plas&city. long-term plasticity (~30 min to lifetime) Long-term potentiation (LTP) / Long-term depression (LTD)

Synap&c Plas&city. long-term plasticity (~30 min to lifetime) Long-term potentiation (LTP) / Long-term depression (LTD) Synap&c Plas&city synaptic connectivity constantly changes in response to activity and other factors During development: provides the basic wiring of the brain s circuits Throughout rest of life: basis

More information

Evaluating the Effect of Spiking Network Parameters on Polychronization

Evaluating the Effect of Spiking Network Parameters on Polychronization Evaluating the Effect of Spiking Network Parameters on Polychronization Panagiotis Ioannou, Matthew Casey and André Grüning Department of Computing, University of Surrey, Guildford, Surrey, GU2 7XH, UK

More information

Neuroplasticity:. Happens in at least 3 ways: - - -

Neuroplasticity:. Happens in at least 3 ways: - - - BRAIN PLASTICITY Neuroplasticity:. Happens in at least 3 ways: - - - Recently, it was found that new neurons and glial cells are born in specific brain regions - reorganization. Brain plasticity occurs

More information

BRAIN PLASTICITY. Neuroplasticity:. Happens in at least 3 ways: - - -

BRAIN PLASTICITY. Neuroplasticity:. Happens in at least 3 ways: - - - BRAIN PLASTICITY Neuroplasticity:. Happens in at least 3 ways: - - - Recently, it was found that new neurons and glial cells are born in specific brain regions - reorganization. Brain plasticity occurs

More information

SAMPLE EXAMINATION QUESTIONS

SAMPLE EXAMINATION QUESTIONS SAMPLE EXAMINATION QUESTIONS PLEASE NOTE, THE QUESTIONS BELOW SAMPLE THE ENTIRE LECTURE COURSE AND THEREORE INCLUDE QUESTIONS ABOUT TOPICS THAT WE HAVE NOT YET COVERED IN CLASS. 1. Which of the following

More information

More dendritic spines, changes in shapes of dendritic spines More NT released by presynaptic membrane

More dendritic spines, changes in shapes of dendritic spines More NT released by presynaptic membrane LEARNING AND MEMORY (p.1) You are your learning and memory! (see movie Total Recall) L&M, two sides of the same coin learning refers more to the acquisition of new information & brain circuits (storage)

More information

11/2/2011. Basic circuit anatomy (the circuit is the same in all parts of the cerebellum)

11/2/2011. Basic circuit anatomy (the circuit is the same in all parts of the cerebellum) 11/2/2011 Neuroscientists have been attracted to the puzzle of the Cerebellum ever since Cajal. The orderly structure, the size of the cerebellum and the regularity of the neural elements demands explanation.

More information

Ch 8. Learning and Memory

Ch 8. Learning and Memory Ch 8. Learning and Memory Cognitive Neuroscience: The Biology of the Mind, 2 nd Ed., M. S. Gazzaniga, R. B. Ivry, and G. R. Mangun, Norton, 2002. Summarized by H.-S. Seok, K. Kim, and B.-T. Zhang Biointelligence

More information

Ch 8. Learning and Memory

Ch 8. Learning and Memory Ch 8. Learning and Memory Cognitive Neuroscience: The Biology of the Mind, 2 nd Ed., M. S. Gazzaniga,, R. B. Ivry,, and G. R. Mangun,, Norton, 2002. Summarized by H.-S. Seok, K. Kim, and B.-T. Zhang Biointelligence

More information

PSY 215 Lecture 13 (3/7/11) Learning & Memory Dr. Achtman PSY 215. Lecture 13 Topic: Mechanisms of Learning and Memory Chapter 13, section 13.

PSY 215 Lecture 13 (3/7/11) Learning & Memory Dr. Achtman PSY 215. Lecture 13 Topic: Mechanisms of Learning and Memory Chapter 13, section 13. PSY 215 Lecture 13 Topic: Mechanisms of Learning and Memory Chapter 13, section 13.2 Corrections: No corrections Announcements: Question # 37 was thrown out on the last test because it was confusing the

More information

CSE 599E Lecture 2: Basic Neuroscience

CSE 599E Lecture 2: Basic Neuroscience CSE 599E Lecture 2: Basic Neuroscience 1 Today s Roadmap The neuron doctrine (or dogma) Neuronal signaling The electrochemical dance of ions Action Potentials (= spikes) Synapses and Synaptic Plasticity

More information

Theories of memory. Memory & brain Cellular bases of learning & memory. Epileptic patient Temporal lobectomy Amnesia

Theories of memory. Memory & brain Cellular bases of learning & memory. Epileptic patient Temporal lobectomy Amnesia Cognitive Neuroscience: The Biology of the Mind, 2 nd Ed., M. S. Gazzaniga, R. B. Ivry, and G. R. Mangun, Norton, 2002. Theories of Sensory, short-term & long-term memories Memory & brain Cellular bases

More information

Synaptic plasticity and hippocampal memory

Synaptic plasticity and hippocampal memory Synaptic plasticity and hippocampal memory Tobias Bast School of Psychology, University of Nottingham tobias.bast@nottingham.ac.uk Synaptic plasticity as the neurophysiological substrate of learning Hebb

More information

Cellular Neurobiology BIPN140

Cellular Neurobiology BIPN140 Cellular Neurobiology BIPN140 1st Midterm Exam Ready for Pickup By the elevator on the 3 rd Floor of Pacific Hall (waiver) Exam Depot Window at the north entrance to Pacific Hall (no waiver) Mon-Fri, 10:00

More information

Synaptic plasticityhippocampus. Neur 8790 Topics in Neuroscience: Neuroplasticity. Outline. Synaptic plasticity hypothesis

Synaptic plasticityhippocampus. Neur 8790 Topics in Neuroscience: Neuroplasticity. Outline. Synaptic plasticity hypothesis Synaptic plasticityhippocampus Neur 8790 Topics in Neuroscience: Neuroplasticity Outline Synaptic plasticity hypothesis Long term potentiation in the hippocampus How it s measured What it looks like Mechanisms

More information

Summarized by. Biointelligence Laboratory, Seoul National University

Summarized by. Biointelligence Laboratory, Seoul National University Ch 8. Learning and Memory Cognitive Neuroscience: The Biology of the Mind, 3 rd Ed., M. S. Gazzaniga, R. B. Ivry, and G. R. Mangun, Norton, 2008. Summarized by H.-S. Seok, K. Kim, and db.-t. TZhang Biointelligence

More information

Memory Systems II How Stored: Engram and LTP. Reading: BCP Chapter 25

Memory Systems II How Stored: Engram and LTP. Reading: BCP Chapter 25 Memory Systems II How Stored: Engram and LTP Reading: BCP Chapter 25 Memory Systems Learning is the acquisition of new knowledge or skills. Memory is the retention of learned information. Many different

More information

NEURAL BASES OF LEARNING AND MEMORY. Arlo Clark-Foos

NEURAL BASES OF LEARNING AND MEMORY. Arlo Clark-Foos NEURAL BASES OF LEARNING AND MEMORY Arlo Clark-Foos You re Making Me Nervous.System Egyptian and Greek views of the brain Behavioral Research vs. Brain Research Ye Olde Hindbrain Cerebellum, Pons, Medulla

More information

CSE 599E Lecture 2: Neurobiology 101

CSE 599E Lecture 2: Neurobiology 101 CSE 599E Lecture 2: Neurobiology 101 Image from http://clasdean.la.asu.edu/news/images/ubep2001/neuron3.jpg 1 Some slides adapted from: http://www.yorku.ca/deniseh/courses/arm%20movements.ppt Today s Roadmap

More information

Lesson 14. The Nervous System. Introduction to Life Processes - SCI 102 1

Lesson 14. The Nervous System. Introduction to Life Processes - SCI 102 1 Lesson 14 The Nervous System Introduction to Life Processes - SCI 102 1 Structures and Functions of Nerve Cells The nervous system has two principal cell types: Neurons (nerve cells) Glia The functions

More information

What is the Role of the Amygdala in Long Term Memory? Jack Pemment. University of Mississippi

What is the Role of the Amygdala in Long Term Memory? Jack Pemment. University of Mississippi LT Memory and the Amygdala 1 Running Head: Role of the amygdala in long term memory What is the Role of the Amygdala in Long Term Memory? Jack Pemment University of Mississippi LT Memory and the Amygdala

More information

Cerebral Cortex: Association Areas and Memory Tutis Vilis

Cerebral Cortex: Association Areas and Memory Tutis Vilis 97 Cerebral Cortex: Association Areas and Memory Tutis Vilis a) Name the 5 main subdivisions of the cerebral cortex. Frontal, temporal, occipital, parietal, and limbic (on the medial side) b) Locate the

More information

Guided Reading Activities

Guided Reading Activities Name Period Chapter 28: Nervous Systems Guided Reading Activities Big idea: Nervous system structure and function Answer the following questions as you read modules 28.1 28.2: 1. Your taste receptors for

More information

Limbic system. Lecture 29, November 10, 2017

Limbic system. Lecture 29, November 10, 2017 Limbic system Lecture 29, November 10, 2017 Circadian rhythms (Latin, approximately a day ) Regulation of our daily rhythm Eating Sleeping Defecating Periods of activity Suprachiasmatic n. http://slideplayer.com/slide/6351731/

More information

Learning and Memory. The Case of H.M.

Learning and Memory. The Case of H.M. Learning and Memory Learning deals with how experience changes the brain Memory refers to how these changes are stored and later reactivated The Case of H.M. H.M. suffered from severe, intractable epilepsy

More information

The storage and recall of memories in the hippocampo-cortical system. Supplementary material. Edmund T Rolls

The storage and recall of memories in the hippocampo-cortical system. Supplementary material. Edmund T Rolls The storage and recall of memories in the hippocampo-cortical system Supplementary material Edmund T Rolls Oxford Centre for Computational Neuroscience, Oxford, England and University of Warwick, Department

More information

Copyright Dr. Franklin B. Krasne, Swimmy

Copyright Dr. Franklin B. Krasne, Swimmy Copyright Dr. Franklin B. Krasne, 2008 Swimmy Advantages of Swimmy 1) Very faithful simulation of neural activity 2) Flawless electrode placement. 3) No extraneous noise issues--including extraneous biological

More information

Synapses and synaptic plasticity. Lubica Benuskova Lecture 8 How neurons communicate How do we learn and remember

Synapses and synaptic plasticity. Lubica Benuskova Lecture 8 How neurons communicate How do we learn and remember Synapses and synaptic plasticity Lubica Benuskova Lecture 8 How neurons communicate How do we learn and remember 1 Brain is comprised of networks of neurons connected and communicating via synapses ~10

More information

συν together απτειν to clasp 2h Neuroscience with Pharmacology Functions and Mechanisms of Reflexes Cogito, ergo sum ( I think therefore I am ) Down

συν together απτειν to clasp 2h Neuroscience with Pharmacology Functions and Mechanisms of Reflexes Cogito, ergo sum ( I think therefore I am ) Down 2h Neuroscience with Pharmacology Functions and Mechanisms of Reflexes Neuroscience is studied at many different levels: from brain, to system, network, neurone, synapse, and molecule... Top Up Down René

More information

LONG TERM MEMORY. Learning Objective Topics. Retrieval and the Brain. Retrieval Neuroscience of Memory. LTP Brain areas Consolidation Reconsolidation

LONG TERM MEMORY. Learning Objective Topics. Retrieval and the Brain. Retrieval Neuroscience of Memory. LTP Brain areas Consolidation Reconsolidation LONG TERM MEMORY Retrieval and the rain Learning Objective Topics Retrieval Neuroscience of Memory LTP rain areas onsolidation Reconsolidation 1 Long-term memory How does info become encoded/stored in

More information

Neuromorphic computing

Neuromorphic computing Neuromorphic computing Robotics M.Sc. programme in Computer Science lorenzo.vannucci@santannapisa.it April 19th, 2018 Outline 1. Introduction 2. Fundamentals of neuroscience 3. Simulating the brain 4.

More information

BIPN140 Lecture 12: Synaptic Plasticity (II)

BIPN140 Lecture 12: Synaptic Plasticity (II) BIPN140 Lecture 12: Synaptic Plasticity (II) 1. Early v.s. Late LTP 2. Long-Term Depression 3. Molecular Mechanisms of Long-Term Depression: NMDA-R dependent 4. Molecular Mechanisms of Long-Term Depression:

More information

Neurobiology and Information Processing Theory: the science behind education

Neurobiology and Information Processing Theory: the science behind education Educational Psychology Professor Moos 4 December, 2008 Neurobiology and Information Processing Theory: the science behind education If you were to ask a fifth grader why he goes to school everyday, he

More information

Okami Study Guide: Chapter 2 1

Okami Study Guide: Chapter 2 1 Okami Study Guide: Chapter 2 1 Chapter in Review 1. The human nervous system is a complex biological system designed for nearly instantaneous communication among billions of neurons throughout the body.

More information

Synaptic plasticity. Mark van Rossum. Institute for Adaptive and Neural Computation University of Edinburgh

Synaptic plasticity. Mark van Rossum. Institute for Adaptive and Neural Computation University of Edinburgh Synaptic plasticity Mark van Rossum Institute for Adaptive and Neural Computation University of Edinburgh 1 Human memory systems 2 Psychologists have split up memory in: Declarative memory * Episodic memory

More information

The Nervous System and the Endocrine System

The Nervous System and the Endocrine System The Nervous System and the Endocrine System Neurons: The Building Blocks of the Nervous System Nervous System The electrochemical communication system of the body Sends messages from the brain to the

More information

Systems Neuroscience Dan Kiper. Today: Wolfger von der Behrens

Systems Neuroscience Dan Kiper. Today: Wolfger von der Behrens Systems Neuroscience Dan Kiper Today: Wolfger von der Behrens wolfger@ini.ethz.ch 18.9.2018 Neurons Pyramidal neuron by Santiago Ramón y Cajal (1852-1934, Nobel prize with Camillo Golgi in 1906) Neurons

More information

Lecture: Introduction to nervous system development

Lecture: Introduction to nervous system development Lecture: Introduction to nervous system development Prof. Ilan Davis, Department of Biochemistry. Wellcome Senior Research Fellow Senior Research Fellow, Jesus College ilan.davis@bioch.ox.ac.uk http://www.ilandavis.com

More information

Meds 371, Systems Neuroscience University of Connecticut Health Center. Memory and Learning. Srdjan Antic, M.D. Department of Neuroscience

Meds 371, Systems Neuroscience University of Connecticut Health Center. Memory and Learning. Srdjan Antic, M.D. Department of Neuroscience Meds 371, Systems Neuroscience University of Connecticut Health Center Memory and Learning Srdjan Antic, M.D. Department of Neuroscience Sources: Purves Textbook: Chapter 31, Memory Review article: Lisman

More information

Long-term synaptic plasticity. N500, 6 Sept., 2016

Long-term synaptic plasticity. N500, 6 Sept., 2016 Long-term synaptic plasticity N500, 6 Sept., 2016 We just finished describing short-term synaptic changes What about long-term changes? How does the brain store information? Outline Origins of the synaptic

More information

LESSON 3.3 WORKBOOK. Why does applying pressure relieve pain?

LESSON 3.3 WORKBOOK. Why does applying pressure relieve pain? Postsynaptic potentials small changes in voltage (membrane potential) due to the binding of neurotransmitter. Receptor-gated ion channels ion channels that open or close in response to the binding of a

More information

3 Basic Neuroscience Based on: Lytton, From Computer to Brain, ch.3, L3 L3

3 Basic Neuroscience Based on: Lytton, From Computer to Brain, ch.3, L3 L3 3 Basic Neuroscience Based on: Lytton, From Computer to Brain, ch.3, L3 L3 3.1 Microscopic view of the nervous system Living tissue is made up of cells. A cell has a fatty membrane and is filled with liquid

More information

Cellular Neurobiology BIPN140

Cellular Neurobiology BIPN140 Cellular Neurobiology BIPN140 Second midterm is next Tuesday!! Covers lectures 7-12 (Synaptic transmission, NT & receptors, intracellular signaling & synaptic plasticity). Review session is on Monday (Nov

More information

The Organism as a Machine. The Brain. Chapter 3: The Brain and the Nervous System

The Organism as a Machine. The Brain. Chapter 3: The Brain and the Nervous System Chapter 3: The Brain and the Nervous System 1 The Brain 1. How are biological influences actualized? What bodily mechanisms produce our behavior? 2. The simple answer is that our brain and our nervous

More information

Brain and behaviour (Wk 6 + 7)

Brain and behaviour (Wk 6 + 7) Brain and behaviour (Wk 6 + 7) What is a neuron? What is the cell body? What is the axon? The basic building block of the nervous system, the individual nerve cell that receives, processes and transmits

More information

Synaptic plasticity. Activity-dependent changes in synaptic strength. Changes in innervation patterns. New synapses or deterioration of synapses.

Synaptic plasticity. Activity-dependent changes in synaptic strength. Changes in innervation patterns. New synapses or deterioration of synapses. Synaptic plasticity Activity-dependent changes in synaptic strength. Changes in innervation patterns. New synapses or deterioration of synapses. Repair/changes in the nervous system after damage. MRC Centre

More information

Exercising Our Minds: Effects of Exercise on Brain Structure & Function

Exercising Our Minds: Effects of Exercise on Brain Structure & Function Public Lecture Exercising Our Minds: Effects of Exercise on Brain Structure & Function Dr. Brian R. Christie Division of Medical Sciences, University of Victoria Cellular and Physiological Sciences, UBC

More information

Learning = an enduring change in behavior, resulting from experience.

Learning = an enduring change in behavior, resulting from experience. Chapter 6: Learning Learning = an enduring change in behavior, resulting from experience. Conditioning = a process in which environmental stimuli and behavioral processes become connected Two types of

More information

3 Basic Neuroscience Based on: Lytton, From Computer to Brain, ch.3, L3 L3 3.1 Microscopic view of the nervous system

3 Basic Neuroscience Based on: Lytton, From Computer to Brain, ch.3, L3 L3 3.1 Microscopic view of the nervous system 3 Basic Neuroscience Based on: Lytton, From Computer to Brain, ch.3, L3 L3 3.1 Microscopic view of the nervous system Living tissue is made up of cells. A cell has a fatty membrane and is filled with liquid

More information

CASE 49. What type of memory is available for conscious retrieval? Which part of the brain stores semantic (factual) memories?

CASE 49. What type of memory is available for conscious retrieval? Which part of the brain stores semantic (factual) memories? CASE 49 A 43-year-old woman is brought to her primary care physician by her family because of concerns about her forgetfulness. The patient has a history of Down syndrome but no other medical problems.

More information

Nervous System Review

Nervous System Review Nervous System Review Name: Block: 1. Which processes are involved in the movement of molecule Y from point X to point Z? A. exocytosis and diffusion B. endocytosis and diffusion C. exocytosis and facilitated

More information

Beyond Vanilla LTP. Spike-timing-dependent-plasticity or STDP

Beyond Vanilla LTP. Spike-timing-dependent-plasticity or STDP Beyond Vanilla LTP Spike-timing-dependent-plasticity or STDP Hebbian learning rule asn W MN,aSN MN Δw ij = μ x j (v i - φ) learning threshold under which LTD can occur Stimulation electrode Recording electrode

More information

Cellular Bioelectricity

Cellular Bioelectricity ELEC ENG 3BB3: Cellular Bioelectricity Notes for Lecture 24 Thursday, March 6, 2014 8. NEURAL ELECTROPHYSIOLOGY We will look at: Structure of the nervous system Sensory transducers and neurons Neural coding

More information

Introduction to Neurobiology

Introduction to Neurobiology Biology 240 General Zoology Introduction to Neurobiology Nervous System functions: communication of information via nerve signals integration and processing of information control of physiological and

More information

Welcome to CSE/NEUBEH 528: Computational Neuroscience

Welcome to CSE/NEUBEH 528: Computational Neuroscience Welcome to CSE/NEUBEH 528: Computational Neuroscience Instructors: Rajesh Rao (rao@cs.uw) Adrienne Fairhall (fairhall@uw) TA: Rich Pang (rpang@uw) 1 Today s Agenda F Course Info and Logistics F Motivation

More information

COGNITIVE SCIENCE 107A. Hippocampus. Jaime A. Pineda, Ph.D.

COGNITIVE SCIENCE 107A. Hippocampus. Jaime A. Pineda, Ph.D. COGNITIVE SCIENCE 107A Hippocampus Jaime A. Pineda, Ph.D. Common (Distributed) Model of Memory Processes Time Course of Memory Processes Long Term Memory DECLARATIVE NON-DECLARATIVE Semantic Episodic Skills

More information

This Lecture: Psychology of Memory and Brain Areas Involved

This Lecture: Psychology of Memory and Brain Areas Involved Lecture 18 (Nov 24 th ): LEARNING & MEMORY #1 Lecture Outline This Lecture: Psychology of Memory and Brain Areas Involved Next lecture: Neural Mechanisms for Memory 1) Psychology of Memory: Short Term

More information

Fear conditioning induces associative long-term potentiation in the amygdala

Fear conditioning induces associative long-term potentiation in the amygdala 11 December 1997 Nature 390, 604-607 (1997) Macmillan Publishers Ltd. Fear conditioning induces associative long-term potentiation in the amygdala MICHAEL T. ROGAN, URSULA V. STÄUBLI & JOSEPH E. LEDOUX

More information

Prof. Anagnostaras, Lecture 7: Fear

Prof. Anagnostaras, Lecture 7: Fear Historical views that thought and emotion were processed separately in the brain Prof. Anagnostaras, Lecture 7: So far, fear is the best understood What is fear? Dictionary: A feeling of agitation and

More information

Plasticity of Cerebral Cortex in Development

Plasticity of Cerebral Cortex in Development Plasticity of Cerebral Cortex in Development Jessica R. Newton and Mriganka Sur Department of Brain & Cognitive Sciences Picower Center for Learning & Memory Massachusetts Institute of Technology Cambridge,

More information

1) Drop off in the Bi 150 box outside Baxter 331 or to the head TA (jcolas).

1) Drop off in the Bi 150 box outside Baxter 331 or  to the head TA (jcolas). Bi/CNS/NB 150 Problem Set 5 Due: Tuesday, Nov. 24, at 4:30 pm Instructions: 1) Drop off in the Bi 150 box outside Baxter 331 or e-mail to the head TA (jcolas). 2) Submit with this cover page. 3) Use a

More information

Council on Chemical Abuse Annual Conference November 2, The Science of Addiction: Rewiring the Brain

Council on Chemical Abuse Annual Conference November 2, The Science of Addiction: Rewiring the Brain Council on Chemical Abuse Annual Conference November 2, 2017 The Science of Addiction: Rewiring the Brain David Reyher, MSW, CAADC Behavioral Health Program Director Alvernia University Defining Addiction

More information

Applied Neuroscience. Conclusion of Science Honors Program Spring 2017

Applied Neuroscience. Conclusion of Science Honors Program Spring 2017 Applied Neuroscience Conclusion of Science Honors Program Spring 2017 Review Circle whichever is greater, A or B. If A = B, circle both: I. A. permeability of a neuronal membrane to Na + during the rise

More information

MEMORY STORAGE. There are three major kinds of storage:

MEMORY STORAGE. There are three major kinds of storage: MEMORY Jill Price was capable of remembering everything that happened last year and several years ago. Memory is the ability to store and retrieve information over time. Memories are the residue of those

More information

Welcome to CSE/NEUBEH 528: Computational Neuroscience

Welcome to CSE/NEUBEH 528: Computational Neuroscience Welcome to CSE/NEUBEH 528: Computational Neuroscience Instructors: Rajesh Rao (rao@cs) Adrienne Fairhall (fairhall@u) TA: Yanping Huang (huangyp@u) 1 Today s Agenda Introduction: Who are we? Course Info

More information

INTRODUCTION TO EDUCATIONAL NEUROSCIENCE

INTRODUCTION TO EDUCATIONAL NEUROSCIENCE INTRODUCTION TO EDUCATIONAL NEUROSCIENCE TRUE OR FALSE? We only use 10% of our brain. Ages zero-three years are more important than any other for learning. There are critical periods for learning important

More information

Behavioral and Motivational mechanisms of Brain. Limbic system and the Hypothalamus

Behavioral and Motivational mechanisms of Brain. Limbic system and the Hypothalamus Behavioral and Motivational mechanisms of Brain Limbic system and the Hypothalamus 1 General functions 1. Control of behavior 2. Control level of activities in different parts of brain 3. Motivational

More information

Perceptual Learning. Motor Learning. Stimulus-Response Learning. Relational Learning

Perceptual Learning. Motor Learning. Stimulus-Response Learning. Relational Learning Introduction to Physiological Psychology Review ksweeney@cogsci.ucsd.edu www.cogsci.ucsd.edu/~ksweeney/psy260.html Learning and Memory Human Communication Emotion 1 Working Memory: What is memory? Limited

More information

Organization of the nervous system. The withdrawal reflex. The central nervous system. Structure of a neuron. Overview

Organization of the nervous system. The withdrawal reflex. The central nervous system. Structure of a neuron. Overview Overview The nervous system- central and peripheral The brain: The source of mind and self Neurons Neuron Communication Chemical messengers Inside the brain Parts of the brain Split Brain Patients Organization

More information

Chapter 23: Wiring the Brain

Chapter 23: Wiring the Brain Chapter 23: Wiring the Brain Introduction Operation of the brain Precise interconnections among 100 billion neurons Brain development Begins as a tube Neurogenesis, synaptogenesis, pathway formation, connections

More information

A tale of a thousand electrodes and one - Combining multielectrode array with patch clamp

A tale of a thousand electrodes and one - Combining multielectrode array with patch clamp A tale of a thousand electrodes and one - Combining multielectrode array with patch clamp Technical Journal Club March 26 2018 Marc Emmenegger The brain Regulation of involuntary and voluntary internal

More information

Basal Ganglia Anatomy, Physiology, and Function. NS201c

Basal Ganglia Anatomy, Physiology, and Function. NS201c Basal Ganglia Anatomy, Physiology, and Function NS201c Human Basal Ganglia Anatomy Basal Ganglia Circuits: The Classical Model of Direct and Indirect Pathway Function Motor Cortex Premotor Cortex + Glutamate

More information

Lateral Inhibition Explains Savings in Conditioning and Extinction

Lateral Inhibition Explains Savings in Conditioning and Extinction Lateral Inhibition Explains Savings in Conditioning and Extinction Ashish Gupta & David C. Noelle ({ashish.gupta, david.noelle}@vanderbilt.edu) Department of Electrical Engineering and Computer Science

More information

Artificial Neural Networks (Ref: Negnevitsky, M. Artificial Intelligence, Chapter 6)

Artificial Neural Networks (Ref: Negnevitsky, M. Artificial Intelligence, Chapter 6) Artificial Neural Networks (Ref: Negnevitsky, M. Artificial Intelligence, Chapter 6) BPNN in Practice Week 3 Lecture Notes page 1 of 1 The Hopfield Network In this network, it was designed on analogy of

More information

Science Honors Program Neurobiology of Development and Disease. Ryan Willett Laboratory of Lloyd Greene Columbia University

Science Honors Program Neurobiology of Development and Disease. Ryan Willett Laboratory of Lloyd Greene Columbia University Science Honors Program Neurobiology of Development and Disease Ryan Willett rtw2004@columbia.edu Laboratory of Lloyd Greene Columbia University Organization of the Human Brain The Central Nervous System

More information

UNIT 5 REVIEW GUIDE - NERVOUS SYSTEM 1) State the 3 functions of the nervous system. 1) 2) 3)

UNIT 5 REVIEW GUIDE - NERVOUS SYSTEM 1) State the 3 functions of the nervous system. 1) 2) 3) UNIT 5 REVIEW GUIDE - NERVOUS SYSTEM State the 3 functions of the nervous system. Briefly describe the general function(s) of each of the following neuron types: a) SENSORY NEURONS: b) INTERNEURONS: c)

More information

Cephalization. Nervous Systems Chapter 49 11/10/2013. Nervous systems consist of circuits of neurons and supporting cells

Cephalization. Nervous Systems Chapter 49 11/10/2013. Nervous systems consist of circuits of neurons and supporting cells Nervous Systems Chapter 49 Cephalization Nervous systems consist of circuits of neurons and supporting cells Nervous system organization usually correlates with lifestyle Organization of the vertebrate

More information

Cellular Mechanisms of Learning and the Biological Basis of Individuality

Cellular Mechanisms of Learning and the Biological Basis of Individuality The Study of Memory Has Two Parts: Cellular Mechanisms of Learning and the Biological Basis of Individuality (1) The Systems Problem of Memory: Where in the brain is memory stored? (2) The Molecular Problem

More information

Neuroscience Flythrough. Lukas Schott und Letita Parcalabescu

Neuroscience Flythrough. Lukas Schott und Letita Parcalabescu Neuroscience Flythrough Lukas Schott und Letita Parcalabescu Content Raw Observations What does the brain look like? Modeling How can we model/replicate the behavior? Testing Does our method make sense?

More information

Module H NERVOUS SYSTEM

Module H NERVOUS SYSTEM Module H NERVOUS SYSTEM Topic from General functions of the nervous system Organization of the nervous system from both anatomical & functional perspectives Gross & microscopic anatomy of nervous tissue

More information

biological psychology, p. 40 The study of the nervous system, especially the brain. neuroscience, p. 40

biological psychology, p. 40 The study of the nervous system, especially the brain. neuroscience, p. 40 biological psychology, p. 40 The specialized branch of psychology that studies the relationship between behavior and bodily processes and system; also called biopsychology or psychobiology. neuroscience,

More information

Class 16 Emotions (10/19/17) Chapter 10

Class 16 Emotions (10/19/17) Chapter 10 Class 16 Emotions (10/19/17) Chapter 10 Notes By: Rashea Psych 302 10/19/17 Emotions The issues o Innate or learned? o Voluntary or involuntary? (conscious/unconscious) o Adaptive behavior or communication?

More information

Butter Food Eat Sandwich Rye Jam Milk Flour Jelly Dough Crust Slice Wine Loaf Toast

Butter Food Eat Sandwich Rye Jam Milk Flour Jelly Dough Crust Slice Wine Loaf Toast Introduction to Physiological Psychology Learning and Memory ksweeney@cogsci.ucsd.edu cogsci.ucsd.edu/~ /~ksweeney/psy260.html Comments on your comments Thank you! Some things that I can change NOW: Slow

More information

synapse neurotransmitters Extension of a neuron, ending in branching terminal fibers, through which messages pass to other neurons, muscles, or glands

synapse neurotransmitters Extension of a neuron, ending in branching terminal fibers, through which messages pass to other neurons, muscles, or glands neuron synapse The junction between the axon tip of a sending neuron and the dendrite of a receiving neuron Building block of the nervous system; nerve cell Chemical messengers that cross the synaptic

More information

9.01 Introduction to Neuroscience Fall 2007

9.01 Introduction to Neuroscience Fall 2007 MIT OpenCourseWare http://ocw.mit.edu 9.01 Introduction to Neuroscience Fall 2007 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms. Working memory short-term

More information