Classes of Neurotransmitters. Neurotransmitters
|
|
- Erica Lester
- 6 years ago
- Views:
Transcription
1 1 Drugs Outline 2 Neurotransmitters Agonists and Antagonists Cocaine & other dopamine agonists Alcohol & its effects / Marijuana & its effects Synthetic & Designer Drugs: Ecstasy 1
2 Classes of Neurotransmitters 3 6 basic classes of NT: Peptides, Gases, Purines, Acetylcholine, Monoamines, and Amino Acids Neurotransmitters 4 Glutamate: general excitatory neurotransmitter GABA: general inhibitory neurotransmitter (Cl - ) Substance P: incoming pain signals Endorphins: pain management Serotonin (5-HT): sleep & mood Dopamine (DA): pleasure center & movement Norepinephrine (NE): sympathetic nervous system (induces aroused, heightened state) Acetylcholine (ACh): parasympathetic nervous system (induces calm, resting state) & motor system 2
3 Synthesis of NTs 5 Enzymes modify basic chemicals Synthesis of Catecholamines 6 Phenylalanine (dietary nutrient) PKU Phenylketonuria genetic deficit of enzyme to metabolize phenylalanine = mental retardation Metabolized to Tyrosine Enzymes modify: Tyrosine Dopa Dopa Dopamine Dopamine Norepinephrine Norepinephrine Epinephrine 3
4 Synaptic events 7 Outline 8 Neurotransmitters Agonists and Antagonists Cocaine & other dopamine agonists Alcohol & its effects / Marijuana & its effects Synthetic & Designer Drugs: Ecstasy 4
5 Agonists 9 A drug which stimulates the effects of a particular neurotransmitter or acts to enhance the transmitter s effect. Agonists 10 5
6 Antagonists 11 A drug which inhibits or counteracts the effects of a particular neurotransmitt er Drug Actions at the Synapse 12 6
7 Drugs working at Dopamine Synapse 13 Norepinephrine (NE) 14 Activates fight or flight resources Depression associated with norepinephrine depletion 7
8 Serotonin (5-HT) 15 Reuptake or monoamine oxidase deactivates Important in sleep regulation, depression, & mood disorders Gamma-aminobutyric Acid (GABA) 16 Main effect is to inhibit action of other neurons Lower levels associated with anxiety or panic attacks decreased levels in Huntington's disease 8
9 Outline 17 Neurotransmitters Agonists and Antagonists Cocaine & other dopamine agonists Alcohol & its effects / Marijuana & its effects Synthetic & Designer Drugs: Ecstasy Dopaminergic System 18 VTA ventral tegmental area Reward, motivation, planning Substantia Nigra Motor control Parkinson's disease associated with dopamine depletion Also associated with schizophrenia 9
10 Cocaine 19 Cocaine blocks the reuptake of dopamine Dopamine Build-up = pleasure feeling in the nucleus of accumbens & heightened arousal / alertness Cocaine blocks the recycling of dopamine everywhere in the CNS In the areas that control your breathing and heart rate dopamine increases activity resulting in heart attacks and loss of breathing control. Overstimulation can kill neurons. Excess dopamine can produce psychosis. Drug Video
11 Ritalin 21 Blocks DA uptake gradually Leads to increased concentration Outline 22 Neurotransmitters Agonists and Antagonists Cocaine & other dopamine agonists Alcohol & its effects / Marijuana & its effects Synthetic & Designer Drugs: Ecstasy 11
12 The Effects of Alcohol 23 Alcohol is very fat-soluble easy access through the blood-brain barrier interfere with the structure of the cell membrane & receptors in the membrane RESULT: inhibits Na + transport into all neurons The effects of alcohol seen in all systems - motor, vision, cognitive, etc. nonspecific to a NT The Effects of Alcohol 24 Alcohol impairs cognitive judgment so that people unintentionally hurt or kill themselves. Alcohol can reduce breathing and heart rate so much that the processes stop. Large amounts and chronic use of alcohol can damage neurons so that they die. 12
13 Outline 25 Neurotransmitters Agonists and Antagonists Cocaine & other dopamine agonists Alcohol & its effects / Marijuana & its effects Synthetic & Designer Drugs: Ecstasy THC Marijuana 26 Endogenous NTs for cannabinoid receptors: Anandamine: inhibits the pre-synaptic release of glutamate in hippocampal neurons ( LTP) inhibits the autonomic nervous system: relaxation, hypothermic, ocular pressure analgesic effects in the spinal cord 2-AG: inhibits LTP in hippocampus and suppresses pain sensations in the spinal cord 13
14 27 Cannabinoid Receptor Density Black labels CB receptors: high density in cerebellum, cortex, basal ganglion, & hippocampus Outline 28 Neurotransmitters Agonists and Antagonists Cocaine & other dopamine agonists Alcohol & its effects / Marijuana & its effects Synthetic & Designer Drugs: Ecstasy 14
15 What is Ecstasy? 29 Synthetic derivative of methamphetamine 30 Ecstasy - mimics both dopamine & serotonin neurotransmitters Ecstasy = artificial stimulation of dopamine and serotonin neurons to a higher degree than normal This over-stimulation can selectively kill the neurons that normally release dopamine & serotonin 15
16 Neurodegenerative Effects 31 Level of dysfunction Neurodegenerative Effects 32 Level of dysfunction 16
17 Drugs & Mechanisms of Action 33 DRUG: Behavioral: Mechanism: Amphetamine Cocaine Methylphenidate (Ritalin) Nicotine Alcohol Opiates Excitement, elevated mood Excitement, elevated mood Increased concentration Stimulant effects, tremors Relaxation, intoxication Relaxation, decrease pain Increased release of dopamine Blocks dopamine reuptake Blocks dopamine reuptake gradually Activates acetylocholine (ACh) receptor (neuromuscular synapses), increases dopamine in nucleus of accumbens Inhibits Na flux, activates GABA, inhibits dopamine Stimulates endorphin receptors Drugs & Mechanisms of Action 34 DRUG: Behavioral: Mechanism: Phencyclidine (PCP) Marijuana LSD Caffeine MDMA (ecstasy) Intoxication, hallucinations thought / memory disorders Intensified sensory, reduced pain, inhibit learning Distorted sensations Increased arousal Euphoria, hallucinations Inhibits NMDA-type glutamate receptors (found in specific areas in the temporal and occipital lobes) Activates anandamide receptors (hippocampus, basal ganglion, cerebellum) Stimulates serotonin receptors Vasoconstrictor, blocks adenosine (effectively increasing dopamine & ACh) Stimulates release of dopamine, activates serotonin receptors 17
18 For next time 35 Read Ch. 5 Study for Exam 1 18
Psychotropic Drugs Critical Thinking - KEY
Open Your Class with This Tomorrow Chasing the Scream: The First and Last Days of the War on s Psychotropic s Critical Thinking - KEY Background: The blood-brain barrier is a network of tightly packed
More informationPSY 302 Lecture 6: The Neurotransmitters (continued) September 12, 2017 Notes by: Desiree Acetylcholine (ACh) CoA + Acetate Acetyl-CoA (mitochondria) (food, vinegar) + Choline ChAT CoA + ACh (lipids, foods)
More informationThe Nervous System. Chapter 4. Neuron 3/9/ Components of the Nervous System
Chapter 4 The Nervous System 1. Components of the Nervous System a. Nerve cells (neurons) Analyze and transmit information Over 100 billion neurons in system Four defined regions Cell body Dendrites Axon
More informationTYPES OF NEUROTRANSMITTERS
TYPES OF NEUROTRANSMITTERS Acetylcholine (ACH) Deals with motor movement and memory. Too much and you will. Too little and you will Lack of ACH has been linked to Alzheimer s disease. Serotonin Involved
More informationPsychology 210. Chemical Messengers. Types of NTs. Properties of Neurotransmitters. Cholinergic Neurons. Small molecule NTs.
Psychology 210 Lecture 3 Kevin R Smith Chemical Messengers Neurotransmitters Act on neurons locally At one synapse Neuromodulators Act on clusters of neurons May not be in the immediate vicinity of where
More informationNeural Communication. Central Nervous System Peripheral Nervous System. Communication in the Nervous System. 4 Common Components of a Neuron
Neural Communication Overview of CNS / PNS Electrical Signaling Chemical Signaling Central Nervous System Peripheral Nervous System Somatic = sensory & motor Autonomic = arousal state Parasympathetic =
More informationChapter 4. Psychopharmacology. Copyright Allyn & Bacon 2004
Chapter 4 Psychopharmacology This multimedia product and its contents are protected under copyright law. The following are prohibited by law: any public performance or display, including transmission of
More informationNervous System (cont)
Nervous System (cont) Dopamine Deals with motor movement and alertness. Lack of dopamine has been linked to Parkinson s disease. Too much has been linked to schizophrenia. Endorphins Involved in pain control.
More informationPart 2: How Your Brain and Nervous System Work
Part 2: How Your Brain and Nervous System Work with Dr. Ritamarie Loscalzo Medical Disclaimer: The information in this presentation is not intended to replace a one onone relationship with a qualified
More informationCell communication. Gated ion channels. Allow specific ions to pass only when gates are open
increase decrease Cell communication Gated ion channels Allow specific ions to pass only when gates are open Triggered by: potential change, chemical binding, temperature change, stretching 1 Voltage-Gated
More informationCell communication. Gated ion channels. Voltage-Gated Na + Channel. Allow specific ions to pass only when gates are open
increase decrease Cell communication Gated ion channels Allow specific ions to pass only when gates are open Voltage-Gated Na + Channel Activation gate ECF Triggered by: change, chemical binding, temperature
More informationNeurotransmitter Systems III Neurochemistry. Reading: BCP Chapter 6
Neurotransmitter Systems III Neurochemistry Reading: BCP Chapter 6 Neurotransmitter Systems Normal function of the human brain requires an orderly set of chemical reactions. Some of the most important
More informationAt a Glance. Background Information. Lesson 3 Drugs Change the Way Neurons Communicate
Lesson 3 Drugs Change the Way Neurons Communicate Overview Students build upon their understanding of neurotransmission by learning how different drugs of abuse disrupt communication between neurons. Students
More informationThe Nervous System Mark Stanford, Ph.D.
The Nervous System Functional Neuroanatomy and How Neurons Communicate Mark Stanford, Ph.D. Santa Clara Valley Health & Hospital System Addiction Medicine and Therapy Services The Nervous System In response
More informationNEUROTRANSMITTERS. Contraction of muscles to move our bodies Release hormones Psychological states of thinking and emotions
NEUROTRANSMITTERS NEURONS Neurons don t actually touch Separated by a tiny fluid-filled gap called a synapse Neural impulses must be ferried across the synapse by chemical messengers called neurotransmitters.
More informationNervous System Notes
Nervous System Notes The nervous system consists of a network of nerve cells or neurons. I. A nervous system is an important part of a cell s (or an organism s) ability to respond to the environment. A.
More informationThe Biological Perspective. Jørg Mørland Senior researcher, Norwegian Institute of Public Health Professor em of Medicine University of Oslo
The Biological Perspective Jørg Mørland Senior researcher, Norwegian Institute of Public Health Professor em of Medicine University of Oslo The Biological Perspective What is it? More than «the» one biological
More informationSynapse. 1. Presynaptic Terminal Button 2. Postsynaptic Membrane 3. Vesicles 4. Synaptic Cleft 5. Neurotransmitters 6.
Synapse 1. Presynaptic Terminal Button 2. Postsynaptic Membrane 3. Vesicles 4. Synaptic Cleft 5. Neurotransmitters 6. Receptor Sites For communication between neurons to occur, an electrical impulse must
More informationNervous System 2. Quick Video
Nervous System 2 McMurray/Tarshish Intro Psych Quick Video https://www.youtube.com/watch? v=4gdjcd68sge 1 10/16/15 Divisions of Nervous System Nervous system divisions CNS PNS Sensory (in) Motor (out)
More informationDrugs, The Brain, and Behavior
Drugs, The Brain, and Behavior John Nyby Department of Biological Sciences Lehigh University What is a drug? Difficult to define Know it when you see it Neuroactive vs Non-Neuroactive drugs Two major types
More informationBIOLOGY 12 TRANSMISSION OF IMPULSES ACROSS SYNAPSES
Name: Pages: 326-327, 341-343 Date: BIOLOGY 12 TRANSMISSION OF IMPULSES ACROSS SYNAPSES How does a nerve impulse make a connection from an axon to the next nerve cell? The impulse must travel from the
More informationBody control systems. Nervous system. Organization of Nervous Systems. The Nervous System. Two types of cells. Organization of Nervous System
Body control systems Nervous system Nervous system Quick Sends message directly to target organ Endocrine system Sends a hormone as a messenger to the target organ Slower acting Longer lasting response
More informationNeurotransmitter Systems I Identification and Distribution. Reading: BCP Chapter 6
Neurotransmitter Systems I Identification and Distribution Reading: BCP Chapter 6 Neurotransmitter Systems Normal function of the human brain requires an orderly set of chemical reactions. Some of the
More informationBiology 3201 Nervous System #6: Effects of Drugs at Synapses
Biology 3201 Nervous System #6: Effects of Drugs at Synapses Toxins prevent the release of acetylcholine ex. Clostridium botulinum (botulism: muscle paralysis)/ Clostridium tetani (tetanus: a disease characterized
More informationAcetylcholine (ACh) Action potential. Agonists. Drugs that enhance the actions of neurotransmitters.
Acetylcholine (ACh) The neurotransmitter responsible for motor control at the junction between nerves and muscles; also involved in mental processes such as learning, memory, sleeping, and dreaming. (See
More information- Neurotransmitters Of The Brain -
- Neurotransmitters Of The Brain - INTRODUCTION Synapsis: a specialized connection between two neurons that permits the transmission of signals in a one-way fashion (presynaptic postsynaptic). Types of
More informationRecreational Chemistry
Recreational Chemistry Well I'm fading away And I can't find the way to the door So I'll sit here on my bed all day While I'm whiling away The best part of a day on the floor I'll sit here on my head all
More informationPsychology in Your Life
Sarah Grison Todd Heatherton Michael Gazzaniga Psychology in Your Life SECOND EDITION Chapter 2 The Role of Biology in Psychology 1 2016 W. W. Norton & Company, Inc. 2.1 How Do Our Nervous Systems Affect
More informationCogs 107b Systems Neuroscience lec9_ neuromodulators and drugs of abuse principle of the week: functional anatomy
Cogs 107b Systems Neuroscience www.dnitz.com lec9_02042010 neuromodulators and drugs of abuse principle of the week: functional anatomy Professor Nitz circa 1986 neurotransmitters: mediating information
More informationNotes are online at The Neuron
Notes are online at http://cogsci.ucsd.edu/~clovett/neuronotescogs17.pdf A. What is a neuron? The Neuron 1. A neuron is a type of cell that receives and transmits information in the Central Nervous System
More informationUNIT 3 - THE NERVOUS SYSTEM. - DIVISIONs - THE NEURON
UNIT 3 - THE NERVOUS SYSTEM - DIVISIONs - THE NEURON CHARACTERISTICS COMPLEXITY: nerve cells connecting allow you to do EVERYTHING you will ever do INTEGRATION: brain pulls all information you get together
More informationNeurons have cell membranes that separate them from the environment outside the neuron.
Neural Communication Lecture 11 A. Resting Potential In this section, we will consider the basic unit of the nervous system the neuron and how neurons communicate with each other. The story of neural communication
More informationCOGS 269. Lecture 1 Spring 2018
COGS 269 Lecture 1 Spring 2018 Psychological Experience Methods of Cognitive Neuroscience Dissociation experiments (patients with brain damage) Neuroimaging experiments Computational modeling Brain damage
More informationCell body, axon, dendrite, synapse
SOME BASIC NEUROSCIENCE Neurons have specialised extensions 1: Label the parts of a neuron by selecting the correct term from the box below. Cell body, axon, dendrite, synapse 1 dendrite synapse cell body
More informationSynapse. Structure & Function. Neurotransmitter Sequence. Integration. History: 10/4/12 original version
Synapse History: 10/4/12 original version Structure & Function (This content is covered in Sinjin's presentation, see link in calendar) Neurotransmitters Synaptic cleft Post-synaptic potential Excitation
More informationNervous System, Neuroanatomy, Neurotransmitters
Nervous System, Neuroanatomy, Neurotransmitters Neurons Structure of neurons Soma Dendrites Spines Axon Myelin Nodes of Ranvier Neurons Structure of neurons Axon collaterals 1 Neurons Structure of neurons
More informationBiological Psychology. Key Point for this Unit: Everything psychological is simultaneously biological!!
Biological Psychology Key Point for this Unit: Everything psychological is simultaneously biological!! NEURON Dendrites Dendrites receive messages from other cells and conduct impulses toward the cell
More informationRick Gilmore :16:57
260-2017-02-13 Rick Gilmore 2017-02-13 10:16:57 Prelude Prelude https://en.wikipedia.org/wiki/mah_nà_mah_nà Today s Topics Neurotransmitters Quiz 2 on Friday. Review Exam 1 on Friday. The influx of which
More informationbiological psychology, p. 40 The study of the nervous system, especially the brain. neuroscience, p. 40
biological psychology, p. 40 The specialized branch of psychology that studies the relationship between behavior and bodily processes and system; also called biopsychology or psychobiology. neuroscience,
More informationChemical Control of Behavior and Brain 1 of 9
Chemical Control of Behavior and Brain 1 of 9 I) INTRO A) Nervous system discussed so far 1) Specific 2) Fast B) Other systems extended in space and time 1) Nonspecific 2) Slow C) Three components that
More informationBasal Ganglia General Info
Basal Ganglia General Info Neural clusters in peripheral nervous system are ganglia. In the central nervous system, they are called nuclei. Should be called Basal Nuclei but usually called Basal Ganglia.
More informationNEURAL TISSUE (NEUROPHYSIOLOGY) PART I (A): NEURONS & NEUROGLIA
PART I (A): NEURONS & NEUROGLIA Neural Tissue Contains 2 kinds of cells: neurons: cells that send and receive signals neuroglia (glial cells): cells that support and protect neurons Neuron Types Sensory
More informationAction Potentials and Synaptic Transmission. BIO 219 Napa Valley College Dr. Adam Ross
Action Potentials and Synaptic Transmission BIO 219 Napa Valley College Dr. Adam Ross Review of action potentials Nodes of Ranvier Nucleus Dendrites Cell body In saltatory conduction, the nerve impulses
More informationChapter 3. Biological Processes
Biological Processes Psychology, Fifth Edition, James S. Nairne What s It For? Biological Solutions Communicating internally Initiating and coordinating behavior Regulating growth and other internal functions
More informationCurricular Requirement 3: Biological Bases of Behavior
Curricular Requirement 3: Biological Bases of Behavior Name: Period: Due Key Terms for CR 3: Biological Bases of Behavior Key Term Definition Application Acetylcholine (Ach) Action potential Adrenal glands
More informationWelcome it is a great day to learn about the Brain
Welcome it is a great day to learn about the Brain What does the Brain do? Stand up Walk around every person you pass tell them a different function the brain performs Do this until you are told to stop
More informationBiological Psychology 2012 Spring 2005 Patterson
Final Exam Biological Psychology 2012 Spring 2005 Patterson There are two versions of this exam. You have version A. Before starting the exam, mark A on question 60. MULTIPLE CHOICE. Choose the one alternative
More informationPsychoactive Drugs & The Brain
Psychoactive Drugs & The Brain Psychoactive Substances & The Brain 1. Psychoactive substances enter the bloodstream via oral administration, inhalation, smoking, or injection 2. Psychoactive substances
More informationReview of Neurochemistry What are neurotransmitters?
Review of Neurochemistry What are neurotransmitters? In molecular terms, neurotransmitters are molecules that ( ) and of neurons by, for example, increasing or decreasing enzymatic activity or altering
More informationprocesses in the central nervous system (CNS), affecting many of the during the course of ethanol treatment. Ethanol stimulates the release of
INTRODUCTION INTRODUCTION Neuroscience research is essential for understanding the biological basis of ethanol-related brain alterations and for identifying the molecular targets for therapeutic compounds
More informationBIPN140 Lecture 8: Synaptic Transmission II
BIPN140 Lecture 8: Synaptic Transmission II 1. Postsynaptic Receptors: Metabotropic & Ionotropic 2. Postsynaptic Responses (Postsynaptic Potentials, PSPs) 3. Neurotransmitters Su (FA16) Chemical Synapse:
More informationThe Nervous System. Anatomy of a Neuron
The Nervous System Chapter 38.1-38.5 Anatomy of a Neuron I. Dendrites II. Cell Body III. Axon Synaptic terminal 1 Neuron Connections dendrites cell body terminal cell body cell body terminals dendrites
More informationThe study of drugs. Pharmacology
The study of drugs Pharmacology Psychopharmacology The study of psychoactive drugs Psychoactive drugs Drugs that influence psychological processes mood emotion perception cognition behavior Psychoactive
More informationBIOL455 COMPARITIVE NEUROBIOLOGY LECTURE#7 DR. OLLIE HULME! FALL 2010! UBC
BIOL455 COMPARITIVE NEUROBIOLOGY LECTURE#7 DR. OLLIE HULME! FALL 2010! UBC Days: MWF, 12-1, room 201! Same old details! Ollieʼs Office hours:! Fri 1.30-4.30pm (may change)! room 3308 Biosciences! Lindsayʼs
More informationNeurotransmitter: dopamine. Physiology of additive drugs. Dopamine and reward. Neurotransmitter: dopamine
Physiology of additive drugs Cocaine, methamphetamine, marijuana, and opiates influence the neurotransmitter dopamine. Neurotransmitter: dopamine Dopamine - a neurotransmitter associated with several functions,
More informationExam 2 PSYC Fall (2 points) Match a brain structure that is located closest to the following portions of the ventricular system
Exam 2 PSYC 2022 Fall 1998 (2 points) What 2 nuclei are collectively called the striatum? (2 points) Match a brain structure that is located closest to the following portions of the ventricular system
More information25 Things To Know. Neurotransmitters
25 Things To Know Neurotransmitters Neurotransmitters 300+ types Neurotransmitters Most Common In Brain Glutamate 90% GABA 9% Other 1% Other 1% Monoamines Dopamine Norepinephrine Epineprine Serotonin Acetylcholine
More informationUnit 2 Multiple Choice test
Name: Date: 1. Resting potential is to action potential as is to. A) adrenal gland; pituitary gland B) sensory neuron; motor neuron C) temporal lobe; occipital lobe D) polarization; depolarization E) dendrite;
More informationName: Period: Chapter 2 Reading Guide The Biology of Mind
Name: Period: Chapter 2 Reading Guide The Biology of Mind The Nervous System (pp. 55-58) 1. What are nerves? 2. Complete the diagram below with definitions of each part of the nervous system. Nervous System
More informationSpecial Topic: Drugs and the Mind
BIOLOGY OF HUMANS Concepts, Applications, and Issues Fifth Edition Judith Goodenough Betty McGuire 8a Special Topic: Drugs and the Mind Lecture Presentation Anne Gasc Hawaii Pacific University and University
More informationBIOLOGICAL PROCESSES
BIOLOGICAL PROCESSES CHAPTER 3 1 LEARNING GOALS Discuss how the nervous system communicates internally. Describe the structure and function of neurons Describe how the neuron transmits information Describe
More informationDrugs, addiction, and the brain
Drugs, addiction, and the brain Topics to cover: What is addiction? How is addiction studied in the lab? The neuroscience of addiction. Caffeine Cocaine Marijuana (THC) What are the properties of addiction?
More informationModules 4 & 6. The Biology of Mind
Modules 4 & 6 The Biology of Mind 1 Neuron - 100 Billion - Communication System Glial cells Cell body (nucleus) Dendrites Axon Axon Terminals (terminal buttons) Synaptic cleft 3 4 Communication Within
More informationIBRO CIHR & UNESCO ADVANCED BEHVIOURAL NEUROSCEINCE SCHOOL KENYA 2008
IBRO CIHR & UNESCO ADVANCED BEHVIOURAL NEUROSCEINCE SCHOOL KENYA 2008 SYNAPTIC FUNCTION & DRUG ACTION Associate Professor Laurie Kellaway Faculty of Health Sciences University of Cape Town WHAT DOES A
More informationNeurobiology of Addiction JeanAnne Johnson Talbert, DHA, APRN BC, FNP, CARN AP
Neurobiology of Addiction JeanAnne Johnson Talbert, DHA, APRN BC, FNP, CARN AP Disclosures This speaker has no conflicts of interest to disclose Objectives Define drug abuse and addiction Identify the
More informationGeneral Functions (3) 1.Sensory gathers information 2.Integrative information is brought together 3.Motor responds to signals, homeostasis
Nervous System Responsible for being aware of the world, coordinating body functions and maintaining homeostasis Information from inside and outside the body is brought to the brain and spinal cord, stimulating
More informationLec 2b Structure and Function of Cells. Cogs17 Cognitive Neuroscience UCSD
Lec 2b Structure and Function of Cells Cogs17 Cognitive Neuroscience UCSD THE SYNAPSE Communication between cells VESICLE Double lipid membrane NTs Exocytosis VESICLE Exocytosis Double lipid membrane
More informationBrain Neurotransmitters
Brain Neurotransmitters * Chemical substances released by electrical impulses into the synaptic cleft from synaptic vesicles of presynaptic membrane * Diffuses to the postsynaptic membrane * Binds to and
More informationPsychoactive drugs Drugs which affect mental processes. Legal but restricted (by prescription only)
Psychoactive drugs Drugs which affect mental processes mood, perception, memory, state of consciousness May be illegal: Heroin Cocaine Legal: Alcohol nicotine Legal but restricted (by prescription only)
More informationThe Cerebral Cortex and Higher Intellectual Functions
The Cerebral Cortex and Higher Intellectual Functions Lobes in a lateral view of left hemisphere Atlas Fig.2-11 The Insula The Hidden Lobe Atlas Fig. 2-11 Atlas Fig. 2-39 Lobes in a lateral view of left
More informationThe Science of Addiction: Genetics and the Brain Webquest
The Science of Addiction: Genetics and the Brain Webquest Part 1: Click here to begin ( might need a laptop not ipad) Complete this chart. Focus on what you DON T REMEMBER FROM HEALTH CLASS. If you know
More informationChapter 3 Part 2: Tolerance, dependence, addiction, & types of drugs
Consciousness and the Two-Track Mind Chapter 3 Part 2: Tolerance, dependence, addiction, & types of drugs Unit 5 ~ AP Psychology ~ Ms. Justice 12: What are tolerance, dependence, and addiction, and what
More informationNeurotransmitters. Chemical transmission of a nerve signal by neurotransmitters at a synapse
Neurotransmitters A chemical released by one neuron that affects another neuron or an effector organ (e.g., muscle, gland, blood vessel). Neurotransmitters are small molecules that serve as messengers
More informationFLASH CARDS. Kalat s Book Chapter 3 Alphabetical
FLASH CARDS www.biologicalpsych.com Kalat s Book Chapter 3 Alphabetical 2-AG 2-AG Found in milk. Combination of arachidonic acid and glycerol. Stands for 2-arachidonoylglycerol. Calcium-dependent chemical
More informationUnderstanding the Brain: What Drugs Can Tell Us
LIVE INTERACTIVE LEARNING @ YOUR DESKTOP Understanding the Brain: What Drugs Can Tell Us Presented by: Dr. Rochelle D. Schwartz-Bloom March 24, 2011 Understanding the Brain: What Drugs Can Tell Us Rochelle
More informationSynaptic transmission
Outline Synaptic transmission Sompol Tapechum M.D., Ph.D. Department of Physiology Faculty of Medicine Siriraj Hospital, Bangkok, Thailand. sisth@mahidol.ac.th 2 Structure of synapse Modes of synaptic
More informationUnit 3: The Biological Bases of Behaviour
Unit 3: The Biological Bases of Behaviour Section 1: Communication in the Nervous System Section 2: Organization in the Nervous System Section 3: Researching the Brain Section 4: The Brain Section 5: Cerebral
More informationFundamentals of the Nervous System and Nervous Tissue: Part C
PowerPoint Lecture Slides prepared by Janice Meeking, Mount Royal College C H A P T E R 11 Fundamentals of the Nervous System and Nervous Tissue: Part C Warm Up What is a neurotransmitter? What is the
More informationNotes: Synapse. Overview. PSYC Summer Professor Claffey PDF. Conversion from an signal to a signal - electrical signal is the
PSYC 170 - Summer 2013 - Professor Claffey Notes: Synapse PDF Overview Conversion from an signal to a signal - electrical signal is the - chemical signal is the Presynaptic - refers to that sends/receives
More informationRecreational drugs 10/11/2014. Drugs of abuse: Recreational drugs. Tobacco. Absorption of Nicotine (pharmacokinetics)
Drugs of abuse: Recreational drugs Dr B.Vahabi Recreational drugs Are alleged to enhance sociability and liberate inhibition Diagnosis and treatment of toxic effects can be very challenging Recent trends:
More informationBiopsychology 2012 sec 003 (Dr. Campeau)
Biopsychology 2012 sec 003 (Dr. Campeau) Study Guide for First Midterm What are some fun facts about the human brain? - there are approximately 100 billion neurons in the brain; - each neuron makes between
More informationCOGNITIVE SCIENCE 107A
COGNITIVE SCIENCE 107A Neurotransmitters Jaime A. Pineda, Ph.D. Exocytosis ~20 Amino Acids Used for Protein Synthesis Non-essential (Our bodies can make them) Alanine (A) Arginine (R) Asparagine (N) Aspartate
More informationCogs 107b Systems Neuroscience Lecture 7: 02/02/16 neuromodulators and drugs of abuse principle of the week:
Cogs 107b Systems Neuroscience www.thiscourse.com/ucsd/cogs107b/wi16 Lecture 7: 02/02/16 neuromodulators and drugs of abuse principle of the week: funcdonal anatomy neurotransmitters: mediating information
More informationNeuron types and Neurotransmitters
Neuron types and Neurotransmitters Faisal I. Mohammed. PhD, MD University of Jordan 1 Transmission of Receptor Information to the Brain the larger the nerve fiber diameter the faster the rate of transmission
More informationParkinsonism or Parkinson s Disease I. Symptoms: Main disorder of movement. Named after, an English physician who described the then known, in 1817.
Parkinsonism or Parkinson s Disease I. Symptoms: Main disorder of movement. Named after, an English physician who described the then known, in 1817. Four (4) hallmark clinical signs: 1) Tremor: (Note -
More informationSection: Chapter 5: Multiple Choice. 1. The structure of synapses is best viewed with a(n):
Section: Chapter 5: Multiple Choice 1. The structure of synapses is best viewed with a(n): p.155 electron microscope. light microscope. confocal microscope. nissle-stained microscopic procedure. 2. Electron
More informationCh. 45 Continues (Have You Read Ch. 45 yet?) u Central Nervous System Synapses - Synaptic functions of neurons - Information transmission via nerve
Ch. 45 Continues (Have You Read Ch. 45 yet?) u Central Nervous System Synapses - Synaptic functions of neurons - Information transmission via nerve impulses - Impulse may be blocked in its transmission
More informationES.S10: Drugs and the Brain Syllabus Spring 2013 Zak Fallows
ES.S10: Drugs and the Brain Syllabus Spring 2013 Zak Fallows About the Class: One-Sentence Description: This class is a multidisciplinary introduction to pharmacology, neurotransmitters, drug mechanisms,
More informationAutonomic Targets. Review (again) Efferent Peripheral NS: The Autonomic & Somatic Motor Divisions
Review (again) Efferent Peripheral NS: The Autonomic & Somatic Motor Divisions Running Problem: Smoking Homeostasis and the Autonomic Division BP, HR, Resp., H 2 O balance, Temp... Mostly dual reciprocal
More informationThe Nervous System. Chapter 35: Biology II
The Nervous System Chapter 35: Biology II Anatomy and Physiology Anatomy: the study of structure Physiology: The study of how living organisms function, including such processes as nutrition, movement,
More informationThe Cerebral Cortex and Higher Intellectual Functions
The Cerebral Cortex and Higher Intellectual Functions The Cerebral cortex consists of 2 cerebral hemisphere and each hemisphere consists of 5 lobes (frontal, parietal,temporal,occipital,insular lobe which
More informationΝευροφυσιολογία και Αισθήσεις
Biomedical Imaging & Applied Optics University of Cyprus Νευροφυσιολογία και Αισθήσεις Διάλεξη 19 Ψυχασθένειες (Mental Illness) Introduction Neurology Branch of medicine concerned with the diagnosis and
More information18. Mind and Addiction
18. Mind and Addiction What is Mind? Chemistry of the Brain: drugs and love 2% body weight Human Brain 20% energy expenditure 100 billion neurons 25,000 connections per neuron 100 trillion connections
More informationPsychoactive Drugs. Psychoactive drug: A chemical substance that alters perceptions and mood.
LP 5C Drugs and alcohol 1 Psychoactive Drugs Psychoactive drug: A chemical substance that alters perceptions and mood. Your textbook characterizes three broad categories of psychoactive drugs Depressants:
More informationWhat are the 6 types of neuroglia and their functions?!
Warm Up! Take out your 11C Notes What are the 6 types of neuroglia and their functions?! Astrocytes Microglia Ependymal Cells Satellite Cells Schwann Cells Oligodendrocytes Support, brace, & nutrient transfer
More informationVisualizing Psychology
Visualizing Psychology by Siri Carpenter & Karen Huffman PowerPoint Lecture Notes Presentation Chapter 2: Neuroscience and Biological Foundations Siri Carpenter, Yale University Karen Huffman, Palomar
More informationPSYCHOACTIVE DRUGS. RG 5c
PSYCHOACTIVE DRUGS RG 5c TODAY S GOALS Can you Explain the difference between stimulants and depressants Identify the major psychoactive drug categories (e.g., depressants, stimulants) and classify specific
More informationPortions from Chapter 6 CHAPTER 7. The Nervous System: Neurons and Synapses. Chapter 7 Outline. and Supporting Cells
CHAPTER 7 The Nervous System: Neurons and Synapses Chapter 7 Outline Neurons and Supporting Cells Activity in Axons The Synapse Acetylcholine as a Neurotransmitter Monoamines as Neurotransmitters Other
More informationObjectives. 1. Outline the criteria that need to be met before a molecule can be classified as neurotransmitter
Neurotransmitters Objectives 1. Outline the criteria that need to be met before a molecule can be classified as neurotransmitter 2. Identify the major neurotransmitter types 3. Mechanism of action of important
More informationResearch Paper 21/08/
Research Paper 21/08/18 20.35 D: 1. The nervous system. 2. The nervous system and drugs. 3. How do drugs effect the central nervous system. 4. Stimulants, hallucinogens, depressants and their effects on
More information