ZIKA VIRUS. Epic and aspects of management
|
|
- Austen Reeves
- 5 years ago
- Views:
Transcription
1 ZIKA VIRUS Epic and aspects of management
2 Classification - Belong to the family Flaviviridae which are mosquitoes borne viruses such as Dengue virus ( DEN V ), West Nile virus ( WN V ), Yellow fever Virus ( YF V ),Chicungunya virus (CHIKV ). - The name Zike is a forest in Uganda which is the main habitat of the animal reservoir ( the Macaque monkey). - Zika virus is a positive-sense single stranded RNA contained into capsid and envelope. This means that the virus can use its RNA directly as messenger RNA to start multiplication. -Polymorphism of many important genetic materials are frequent with possibility of recombination. Which is rare among other Flaviviruses. This has important impact on viral spread, zoonotic maintenance and epidemiological potential
3 Genetic analysis distinguishes between two distinct lineages, African and Asian, both emerged from Africa before spreading in the late 40`s to the to south east Asia and pacific islands (Polynesia ),then to the American continent. - The principal host are Macaque monkeys which live in Zika forest, Uganda.
4 Pathogenesis - Aedes mosquitoes family ( Egypti and Africanus species ) is implicated as vectors. -Unlike other Arboviruses, mosquitoes does not play any part in Zika virus life cycle, which means the direct transmission from patient to healthy individuals through insect bite. - The virus is inoculated into skin by carrying mosquito, facilitated by specific receptors, then spread to blood stream. -One of the characteristic s of Aedes aegypti is in door resting behavior which make it very efficient vector of Arboviruses (Dingu, Chikungunia, Zika ).
5 The insect habitat in bedrooms and living rooms is about 1.5 m. height. This is very important in the strategy of insect elimination using insecticide s spraying procedures. The second important route of infection is sexual transmission and genital persistence of the virus is as important as vector transmission. It was found that the time of exposure to the virus is crucial for the infection (during estrus phase,the female genitals are resistant to the virus The viral particles can persist and recovered in vaginal wash for 10 days after exposure.
6 Inc Severe cases with neurological complications (meningitis,meningioencephetitis, Guillan-Barre ) are not uncommon. Microcephaly in newborns of infected mother is the worst and most common manifestation of the disease. Mitosis abnormalities and Apoptotic death of human progenerator cells ( both in adults and developing nervous system in fetuses ) are frequently disrupted.
7 Using FISH (Fluorescence In Situ Hybridization )method analysis of chromosomes 12 and 17 showed increased frequency of abnormality ( monosomy,trisomy,polysomy )
8 -Incubation time is 3-7 days before symptoms appear. - Most cases are asymptomatic with mild self limiting flu like disease. - Similarity of symptoms of other Arboviruses infections confound right diagnosis.
9 - Rare death cases were reported in patient suffering other immunopathies ( Rheumatoid arthritis, Lupus, sickle cells, chronic corticosteroids use, alcoholism ). - The stage of pregnancy at which the mother becomes infected seems to affect the risk to the fetus. One study estimated the risk of developing microcephaly at about 1 % during the first trimester with less chance during the rest pregnancy time.
10 In a study on group of pregnant women developed symptoms ( rash, headache ) during pregnancy in Brazil, fetuses development was evaluated: The fetuses presented with brain lesions Amniotic fluid and tissue analysis confirmed Zika infection 27 % of newborns died within two days of life with evidence of cerebral inflammation and focal calcification. Eye Arthrogyrposis seen in few cases. Microcephaly was the prominent feature in most cases
11 Some cases showed head circumference within normal range although the cerebral tissue was small. This was due to Hydrocephalus symptoms in those cases
12 -Historically, symptomatic Zika virus infections were limited to sporadic cases or clusters of exposed humans. - Major outbreaks occurred in 2007 in Polynesia to spread later in epic proportions to Americas - Sporadic cases were reported in Europe, restricted to travelers from affected areas. This might due to the lack of vector insects.
13 Transmission - Viral particles can cross placenta to infect fetus in the uterine. Virus particles detected in fetus tissues from infected mothers - Possible transmission through blood products and organ transplant procedures. -Possible needle sticks injuries. Cases were reported in health workers following accidental instrumental inoculation. -Possible sexual transmission from infected males. Viral particles were detected in seminal fluids after up to 6 months and transmitted to female partner - No convincing evidence yet to support breast feeding transmission to babies although the virus was detected in milk of infected mothers. - Most reported cases of none placental transmission were coincided with contact with or exposure to mosquitoes, which cast some doubts on these routes.
14 Laboratory findings - Mild elevation in inflammatory markers (CRP, fibrinogen ). -Elevation in Liver enzymes,ld. CBC profile mostly normal with frequent finding of nonspecific changes (thrombocytopenia, leucopenia ) which coincide with viral infections None of these finding are diagnostic.most are found in other viruses in the family ( DENV,CHIKV )
15 DIAGNOSIS - Clinical diagnosis is unreliable because of symptoms overlaps with other Arboviruses. -Molecular and immunological procedures are available commercially. - Evaluation for Zika. CHIKV, DENV, should be considered concurrently for all patients with acute fever, rash, myalgia or arthralgia after travel to endemic areas. - PCR based assays are available for definitive diagnosis in large reference laboratories. - Serological assays were approved by FDA for restricted use as emergency first line procedures.
16 - Molecular amplification procedures (Reverse Transcriptase PCR ) are most specific and preferred approach during acute phase with viremia ( 3-7 days from onset ).Saliva samples can be processed with reliable results. Virus particles are detected in urine samples for up to 14 days after onset. The virus has been found to survive longer in urine than serum or saliva. The virus was detected in seminal fluids after 6 months of exposure.the virus can be detected in vaginal secretions for up to 10 daysa after sexual contact with infected male - The virus does not establish any latency phase in the host. -Serological tests for IgM, IgG abs are available commercially.igm abs can be detected within 3 days of onset. - Cross reactions were seen with closely related flaviviruses (DNV, WNV ) as well as vaccines to flaviviruses
17 Testing strategy Nucleic Acid Tests (NAT ) for patients presented with symptoms onset less than 7 days. Serology and or NAT in patients with symptoms onset more than 7 days with preference to serological procedures because viremea phase drops rapidly after 7 days. Serology tests for other flaviviruses ( DIN. CHIK. ) should be performs concurrently because of cross reactivity between them. A novel serological Elisa based procedure using None structural Protein 1 (NSP 1), to detect Abs to Zika virus with minimum crossreactivity with DIN V abs ( IgG,IgM ).
18 Management & Prevention 1- Mosquitoes avoidance and control: - Covering skin and exposed areas to prevent biting - Using insects repellant - Controlling breading places ( still water. Ponds ) - Using insecticides 2- Sexual transmission avoidance: - Using condoms for six months after visiting endemic areas - Avoiding pregnancy for at least six weeks after visiting endemic areas. Some studies reported detection of the virus in women after 3.5 months of symptoms.
19 3- Infecting mosquitoes with bacterial sp. (Wollbachia ) which make them resistant to Zika virus 4- Spreading sterile male mosquitoes 5- Spreading genetically modified strain of insects developed in Brazil (Oxitec OX513 A ) 7- Vaccination: No available successful vaccines until now. A new approach using DNA based vaccine for Fliviviruses. The DNA coding for immunogenic protein and when injected in tissues, will generates hummoral and cellular immune non specific response to the viruses. Preliminary results show that it prevent infection after exposure to the virus
What s Lurking out there??????
What s Lurking out there?????? Dave Warshauer, PhD, D(ABMM) Deputy Director, Communicable Diseases Wisconsin State Laboratory of Hygiene david.warshauer@slh.wisc.edu WISCONSIN STATE LABORATORY OF HYGIENE
More informationZIKA VIRUS. John J. Russell MD May 27, 2016
John J. Russell MD May 27, 2016 HISTORY Discovered 1947 Zika Forest of Uganda in rhesus monkeys, thus the name Found in humans in Africa in 1952 Not considered a public health threat until outbreak in
More informationPublic Health Image Library. CDC/ Cynthia Goldsmith. Image #
Zika Virus Fredrick M. Abrahamian, D.O., FACEP, FIDSA Clinical Professor of Medicine UCLA School of Medicine Director of Education Department of Emergency Medicine Olive View-UCLA Medical Center Sylmar,
More informationEuropean Centre for Disease Prevention and Control. Zika virus disease
European Centre for Disease Prevention and Control Zika virus disease Stockholm, 19 February 2016 Background information Zika virus is a member of the Flaviviridae family and transmitted by mosquitoes
More informationZika Virus: The Olympics and Beyond
Zika Virus: The Olympics and Beyond Alice Pong, MD Pediatric Infectious Diseases Rady Children s Hospital-San Diego University of California, San Diego Disclosures I have no disclosures to report 1 Objectives
More informationEverything you ever wanted to know about Zika Virus Disease
Everything you ever wanted to know about Zika Virus Disease (in 14 slides) Jon Temte, MD/PhD University of Wisconsin School of Medicine and Public Health 28 January 2016 Zika Virus mosquito-borne flavivirus
More informationZika Virus. ZIKA VIRUS & PREGNANCY Stephen Champlin, M.D. FLAVIVIRIDAE VIRUS SPECTRUM. Virus family Flaviviridae
ZIKA VIRUS & PREGNANCY Stephen Champlin, M.D. Zika Virus Virus family Flaviviridae Positive sense, single-stranded RNA virus FLAVIVIRIDAE VIRUS SPECTRUM Arbovirus - spread by arthropods to mammals Flaviviridae
More informationOutbreaks of Zika Virus: What Do We Know? Presented by Dr Jonathan Darbro Mosquito Control Lab, QIMR Berhgofer 15 September 2016
Outbreaks of Zika Virus: What Do We Know? Presented by Dr Jonathan Darbro Mosquito Control Lab, QIMR Berhgofer 15 September 2016 Overview History Distribution Modes of Transmission Symptoms Some Causal
More informationEpidemiology and entomology of the Zika virus outbreak
Epidemiology and entomology of the Zika virus outbreak M A T T H E W B A Y L I S I N S T I T U T E O F I N F E C T I O N A N D G L O B A L H E A L T H U N I V E R S I T Y O F L I V E R P O O L Zika in
More informationZika Virus Basics. Flaviviridae Flavivirus Disease Vector Vaccine *Dengue (serotypes 1-4) Zika Virus Basics. Zika Virus Transmission Cycle
Zika: Infection,, and Protection Roxanne P. Liles, Ph.D., MLS(ASCP) CM Assistant Professor of Biology Louisiana State University at Alexandria 318-473-6518 rliles@lsua.edu Zika Virus Basics Virion: Enveloped
More informationZika Virus. Disclosure. Zika Virus 8/26/2016
Zika Virus Robert Wittler, MD Disclosure I have no relevant financial relationships with the manufacturers(s) of any commercial products(s) and/or provider of commercial services discussed in this CME
More informationZika Virus. Robert Wittler, MD
Zika Virus Robert Wittler, MD Disclosure I have no relevant financial relationships with the manufacturers(s) of any commercial products(s) and/or provider of commercial services discussed in this CME
More informationGuidance for Investigation and Management of Zika Virus Infection
Guidance for Investigation and Management of Zika Virus Infection Update: February 11, 2016 Public Health Agency of Canada has issued recommendations from the Committee to Advise on Tropical Medicine and
More informationZika Virus Update for Emergency Care Providers
Zika Virus Update for Emergency Care Providers What is this Zika Virus? Jeff Doerr Epidemiologist Southeastern Idaho Public Health Zika Virus Single stranded RNA virus Genus Flavivirus, Family Flaviviridae
More informationTHE ZIKA VIRUS. August 3, Sonia G. Pandit, MPH MBA Chief Executive Officer The Pandit Group
THE ZIKA VIRUS August 3, 2016 Sonia G. Pandit, MPH MBA Chief Executive Officer The Pandit Group sonia@thepanditgroup.com 443-990-1372 www.thepanditgroup.com What Makes Zika Unique? Viral disease (Flavi
More informationA RELOOK AT ZIKA VIRAL INFECTION AND ITS LATEST OUTBREAK IN INDIA
24 th December 2018 A RELOOK AT ZIKA VIRAL INFECTION AND ITS LATEST OUTBREAK IN INDIA BACKGROUND Zika virus infection, which erupted on a large scale in 2015-2016, has infected more than 1.5 million people.
More informationZika Virus Dr Conor Doherty
Zika Virus Dr Conor Doherty Zika Virus Single stranded RNA enveloped icosahedral virus Flavivirus (e.g. dengue, yellow feve er) First described in Zika forest in Uganda in 1947 Initial enzootic monkey
More informationZika Virus. Maternal & Fetal Effects. John P. Elliott, MD Medical Director, Valley Perinatal Services Phoenix, Arizona
Zika Virus Maternal & Fetal Effects John P. Elliott, MD Medical Director, Valley Perinatal Services Phoenix, Arizona Objective of Presentation Sneeka Peeka at Zika Disclosure I have nothing to disclose
More informationZIKA VIRUS OUTBREAK. JANET B. EDDY M.D. KU-WICHITA PGY2 OBSTETRICS AND GYNECOLOGY RESIDENCY Dominican Republic 2016
ZIKA VIRUS OUTBREAK JANET B. EDDY M.D. KU-WICHITA PGY2 OBSTETRICS AND GYNECOLOGY RESIDENCY Dominican Republic 2016 Zika time line 1947: 1 st isolated in rhesus monkey in Zika forest of Uganda 1 12/2013:
More informationPresentation Overview
Presentation Overview Characteristics of Zika virus Characteristics of Zika virus infection Epidemiology and outbreaks Vector and transmission Clinical symptoms Diagnosis and testing Treatment and prevention
More informationZika Virus Identifying an Emerging Threat. Florida Department of Health in Miami-Dade County Epidemiology, Disease Control, & Immunization Services
Zika Virus Identifying an Emerging Threat Florida Department of Health in Miami-Dade County Epidemiology, Disease Control, & Immunization Services What is Zika Virus? Zika virus is a vector-borne disease
More informationObjectives. Dengue, Chikungunya and Zika Virus Infection: Answers to Common Questions. Case 1. Dengue Introduction 10/15/2018
Dengue, Chikungunya and Zika Virus Infection: Answers to Common Questions Wayne Ghesquiere MD FRCPC Infectious Diseases Consultant Clinical Assistant Prof, UBC Victoria, BC Objectives Discuss common Arbovirus
More informationZika Virus in the Primary Care Setting
Zika Virus in the Primary Care Setting Monica McArthur, MD PhD Assistant Professor of Pediatrics Center for Vaccine Development University of Maryland School of Medicine Maryland Chapter ACP Meeting 17
More informationGeneral Description. Significance
General Description The Zika virus is a member of the Flavivirus family, and is a small, enveloped virus (easy to kill with a hospital disinfectant). Zika virus is an emerging mosquito-borne virus that
More informationZika Virus Guidance for Medical Providers. Denise Smith, PHN, MPA Director of Disease Control Kern County Public Health Services Department
Zika Virus Guidance for Medical Providers Denise Smith, PHN, MPA Director of Disease Control Kern County Public Health Services Department Kern Perinatal Symposium March 3, 2017 CME DISCLOSURE The Planners,
More informationZika and Emerging Infectious Diseases. Clifford T. Mauriello, MD, FAAP Assistant Clinical Professor May 31, 2016
Zika and Emerging Infectious Diseases Clifford T. Mauriello, MD, FAAP Assistant Clinical Professor May 31, 2016 Famous Last Words The time has come to close the book on infectious diseases. We have basically
More informationZIKA VIRUS. Causes, Symptoms, Treatment and Prevention
ZIKA VIRUS Causes, Symptoms, Treatment and Prevention Introduction Zika virus is spread to people through mosquito bites. The most common symptoms of Zika virus disease are fever, rash, joint pain, and
More informationWhen infections go viral Zika Virus
When infections go viral Zika Virus John Fangman, MD Associate Professor of Medicine (Infectious Diseases) Senior Medical Director of Ambulatory, Medical College Physicians Medical College of Wisconsin
More informationZika Virus Update. Partner Webinar 05/12/2016
Zika Virus Update Partner Webinar 05/12/2016 Today s presenters Patricia Quinlisk, MD, MPH, Medical Director /State Epidemiologist Ann Garvey, DVM, MPH, MA, State Public Health Veterinarian/ Deputy State
More informationZika Outbreak Discussion
Zika Outbreak Discussion May 10, 2016 2016 Zurich Healthcare Customer Symposium Speakers Krishna Lynch Senior Healthcare Risk Consultant Zurich Clayton Shoup Business Director, Workers Compensation Zurich
More informationZika virus: a new global threat for Dr Gina McAllister Clinical Scientist, Virology
Zika virus: a new global threat for 2016 Dr Gina McAllister Clinical Scientist, Virology Moritz U. G. Kraemer and others The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus
More informationZika Virus. Centers for Disease Control and Prevention
Centers for Disease Control and Prevention Zika Virus Ingrid Rabe Medical Epidemiologist Arboviral Diseases Branch Centers for Disease Control and Prevention February 1, 2016 Zika Virus Single stranded
More informationZika virus infection Interim clinical guidance for Primary Care
Zika virus infection Interim clinical guidance for Primary Care Zika virus infection is a notifiable disease in Ireland under the Infectious Diseases (Amendment) Regulations 2016 (S.I.. 276 of 2016). All
More informationZika virus: Interim guidance information for LMCs (midwives), GPs and other health professionals dealing with Zika virus in pregnancy 5 February 2016
Zika virus: Interim guidance information for LMCs (midwives), GPs and other health professionals dealing with Zika virus in pregnancy 5 February 2016 This interim guidance is the result of consultation
More informationZika: Deet, There It Is. Anna Powell, MD Reproductive Infectious Disease Fellow THEGOS
Zika: Deet, There It Is Anna Powell, MD Reproductive Infectious Disease Fellow THEGOS Disclosure I have no financial disclosures or conflicts of interest Lessons from Rubella At peak of rubella epidemic
More informationZika Virus. Frequently Asked Questions: Zika Virus and Pregnancy Version
Zika Virus Frequently Asked Questions: Zika Virus and Pregnancy Version What is Zika? Zika is a viral infection that usually causes a mild illness that typically lasts between 2 and 7 days. 80% of people
More informationGeographic distribution ZIKV
Shelley M. Wood, RN, BSN, CEN March 16, 2016 Geographic distribution ZIKV 1947 2007 http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2819875/ 1 Current Active Zika transmission WHO declared global health threat
More informationRelevant Communicable Diseases in HCT/Ps
Relevant Communicable Diseases in HCT/Ps Phyllis I. Warkentin, MD Professor of Pathology and Pediatrics University of Nebraska Medical Center FACT Chief Medical Officer Relevant Communicable Diseases in
More informationSPECIALIZED FAMILY CARE Provider Training
SPECIALIZED FAMILY CARE Provider Training Category: Health Issue Title: Zika Virus Materials: Centers for Disease Control Fact Sheet on Zika Virus Goal: Specialized Family Care Provider to learn the risks,
More informationCarol M. Smith, M.D., M.P.H. Commissioner of Health and Mental Health Ulster County Department of Health and Mental Health May 20, 2016
Carol M. Smith, M.D., M.P.H. Commissioner of Health and Mental Health Ulster County Department of Health and Mental Health May 20, 2016 Michael Hein County Executive Zika virus was first discovered in
More information10/6/2016. Outline. Zika, Dengue, and Chikungunya Viruses in the Americas Oh My! Some Mosquito-Borne Arboviruses
Zika, Dengue, and Chikungunya Viruses in the Americas Oh My! Geoffrey A. Weinberg, M.D., FAAP, FIDSA, FPIDS Professor of Pediatrics Director, Pediatric HIV Program Division of Pediatric Infectious Diseases
More informationZika virus: clinical and epidemiological features
Zika virus: clinical and epidemiological features Dominic Dwyer Medical Virologist, Westmead Hospital Director, ICPMR and Pathology West NSW Health Pathology dominic.dwyer@sydney.edu.au, Zika virus Flavivirus
More informationWhat is Zika virus (Zika)?
Zika Virus Basics What is Zika virus (Zika)? Viral infection caused by the bite of an infected mosquito Linked to serious birth defects and other poor pregnancy outcomes in babies of mothers who were infected
More informationThis memo is intended to provide information to NC clinicians and laboratories regarding diagnosis, management and reporting of Zika virus infection.
May 18, 2016 (replaces version dated March 31, 2016) To: From: North Carolina Health Care Providers and Laboratories Megan Davies, MD, State Epidemiologist Scott Zimmerman, DrPH, MPH, HCLD (ABB), State
More informationWhat is Zika virus? What are the symptoms and complications of Zika virus infection? Are cases expected in Canada?
What is Zika virus? Zika Virus Update for Healthcare Professionals Updated June 22, 2016; italicized text indicates clarification of wording contained in previous versions. Zika virus is a Flavivirus transmitted
More informationZIKA VIRUS. Annanya Gangopadhyay*, Shubhrajit Mantry, Abhinay Chhetri, Sudip das
ZIKA VIRUS Annanya Gangopadhyay*, Shubhrajit Mantry, Abhinay Chhetri, Sudip das, Himalayan Pharmacy Institute, Majhitar, Rangpo, E. Sikkim 737136, INDIA ARTICLE INFO: Article history: Received: 02 December
More informationFY 2017 President s Budget Request Overview for the National Center on Birth Defects and Developmental Disabilities
National Center on Birth Defects and Developmental Disabilities FY 2017 President s Budget Request Overview for the National Center on Birth Defects and Developmental Disabilities Sascha Chaney Associate
More informationTown of Wolfeboro New Hampshire Health Notice Wolfeboro Public Health Officer Information Sheet Zika Virus
Aedes Zika Virus Information Sheet Town of Wolfeboro New Hampshire Health Notice Wolfeboro Public Health Officer Information Sheet Zika Virus The Zika Virus is a mosquito borne illness spread by the Aedes
More informationWhat You Need to Know ZIKA VIRUS
What You Need to Know ZIKA VIRUS What is Zika Virus? Zika virus is a flavivirus related to dengue, West Nile, yellow fever and Japanese encephalitis Zika virus first identified in 1947 and named for the
More information*This response is constantly evolving and recommendations in this presentation may change over time, please call your district epidemiologist or a
*This response is constantly evolving and recommendations in this presentation may change over time, please call your district epidemiologist or a GDPH epidemiologist 404-657-2588, 8-5 pm M-F for current
More informationZika Virus. Zika Virus. Priyanka Halde. 3 rd Year, MGM Institute of Health Sciences, Navi Mumbai December, 2016
Priyanka Halde 3 rd Year, MGM Institute of Health Sciences, Navi Mumbai December, 2016 Introduction Zika virus is an emerging mosquito-borne virus that was first identified in Zika Forest in Uganda in
More informationZika Virus and Prevention in Mississippi
Mississippi State Department of Health Mississippi Morbidity Report Volume 32, Number 1 July 2016 Background: Zika Virus and Prevention in Mississippi Key Messages: Zika virus infection during pregnancy
More informationZika Virus. Lee Green Vector-Borne Epidemiologist Indiana State Department of Health. April 13, 2016
Zika Virus Lee Green Vector-Borne Epidemiologist Indiana State Department of Health April 13, 2016 What Is It? Flavivirus WNV Dengue St. Louis Encephalitis Yellow Fever Tick Borne Encephalitis Single stranded
More informationUpdates in Infectious Diseases. Kelley Struble, DO, MS St. John Physicians Infectious Disease September 30, 2016
Updates in Infectious Diseases Kelley Struble, DO, MS St. John Physicians Infectious Disease September 30, 2016 Disclosures No financial relationships or affiliations to disclose Overview Activity Pre-Test
More informationModule Three About Zika Virus: What is Known and Not Known
Module Three About Zika Virus: What is Known and Not Known HOUSEKEEPING For educational and quality improvement purposes, this TeleECHO Clinic will be recorded By participating in this clinic, you are
More informationWest Nile Virus. By Frank Riusech
West Nile Virus By Frank Riusech Disease Etiology: West Nile virus(wnv), genus, flavivirus is positive- stranded RNA arbovirus (arthropod- borne), belonging to the Flaviviridae family. Included in this
More informationZIKA COLLABORATION MEETING: CLINICAL PERSPECTIVE. Julius L. Tonzel Vector-borne Diseases Epidemiologist Louisiana Office of Public Health
ZIKA COLLABORATION MEETING: CLINICAL PERSPECTIVE Julius L. Tonzel Vector-borne Diseases Epidemiologist Louisiana Office of Public Health DISCLOSURE STATEMENT The speakers, the speakers spouses, and the
More informationUPDATE ON ZIKA VIRUS INFECTION
IMPORTANCE UPDATE ON ZIKA VIRUS INFECTION Robert A. Broughton, M.D. Professor of Pediatrics Division of Infectious Diseases E-mail: rbrough@uky.edu WHO declared Zika a Public Health Emergency of International
More informationZIKA Virus and Mosquito Management. ACCG Rosmarie Kelly, PhD MPH 30 April 16
ZIKA Virus and Mosquito Management ACCG Rosmarie Kelly, PhD MPH 30 April 16 What is Zika Virus? Zika virus (ZIKV) is a flavivirus related to yellow fever, dengue, West Nile, and Japanese encephalitis viruses.
More informationZika Virus and Control Efforts in Arizona
Zika Virus and Control Efforts in Arizona Irene Ruberto, MPH, PhD Epidemiologist Office of Infectious Disease Services Arizona Department of Health Services November 10, 2016 Goal by Humbletree (cc by-nc
More informationAn Introduction to Dengue, Zika and Chikungunya Viruses
An Introduction to Dengue, Zika and Chikungunya Viruses Natalie Marzec, MD, MPH Zoonoses Epidemiologist 2017 Global Health and Disasters Course Objectives Arbovirus Overview Public Health Activities Clinical
More informationZika Virus. Division of Infectious Disease Department of Internal Medicine Global Health Program Conference Dora Lebron, MD Alexandra Stang, MD
Zika Virus Division of Infectious Disease Department of Internal Medicine Global Health Program Conference Dora Lebron, MD Alexandra Stang, MD Zika Virus ZIKV is a mosquito-borne ssrna flavivirus from
More informationMercer MRC A Newsletter for and about our volunteers
Mercer MRC A Newsletter for and about our volunteers May 2017 Volume 1, Issue 5 Brian Hughes, County Executive Marygrace Billek, Director, Dept. of Human Services Lyme Disease Awareness Month May is Lyme
More informationZika Virus. It may be devastating, But we might just get one step ahead of it. Learning in Retirement Winter 2017 Daniel Burnside. photo: Newsweek.
Zika Virus It may be devastating, But we might just get one step ahead of it Learning in Retirement Winter 2017 Daniel Burnside photo: Newsweek.com INTRODUCTION TO VIRUSES STRUCTURE GENOME LIFE CYCLE
More informationCenters for Disease Control and Prevention Zika Virus in Pregnancy What Midwives Need To Know
Centers for Disease Control and Prevention Zika Virus in Pregnancy What Midwives Need To Know Margaret A. Lampe, RN, MPH Pregnancy and Birth Defects Surveillance Team Zika Virus Emergency Response U.S.
More informationFIRST CONFIRMED CASE OF IMPORTED ZIKA VIRUS IN HOUSTON, TEXAS. Preventing Transmission
FIRST CONFIRMED CASE OF IMPORTED ZIKA VIRUS IN HOUSTON, TEXAS Preventing Transmission Objectives Discuss the epidemiology of Zika virus Describe the Zika case investigation of the first confirmed case
More informationYellow fever. Key facts
From: http://www.who.int/en/news-room/fact-sheets/detail/yellow-fever WHO/E. Soteras Jalil Yellow fever 14 March 2018 Key facts Yellow fever is an acute viral haemorrhagic disease transmitted by infected
More informationZika Virus: What We Know and Don t Know Meg Fisher, MD Medical Director. Disclosures. Objectives
Zika Virus: What We Know and Don t Know Meg Fisher, MD Medical Director Disclosures I have no financial disclosures. I do not plan to discuss off label uses of medications. Objectives Discuss the epidemiology
More informationZika Pregnancy and Birth Defects Surveillance
Zika Pregnancy and Birth Defects Surveillance Sowmya Adibhatla, MPH Zika Surveillance and Response Coordinator Overview History/Background Zika cases update Zika virus infection Testing guidance Recommendations
More informationWrapping Our Heads Around the Outbreak
Wrapping Our Heads Around the Outbreak An Update on the Zika Virus P. Zach White, PharmD PGY1 Pharmacy Resident Mayo Eugenio Litta Children s Hospital Pharmacy Grand Rounds June 7, 2016 2015 MFMER slide-1
More informationFact Sheet for Health Care Providers: Interpreting Results from the Aptima Zika Virus assay. September 7, 2016
Dear Health Care Provider: Fact Sheet for Health Care Providers: Interpreting Results from the Aptima Zika Virus assay September 7, 2016 The U.S. Food and Drug Administration (FDA) has issued an Emergency
More informationZIKA Jordan H. Perlow MD Banner University Medical Center Division of Maternal Fetal Medicine Phoenix Perinatal Asoociates
ZIKA Jordan H. Perlow MD Banner University Medical Center Division of Maternal Fetal Medicine Phoenix Perinatal Asoociates Disclosures I have no relevant financial relationships to disclose or conflicts
More information: AccuPower ZIKV(DENV, CHIKV) Multiplex Real-Time RT-PCR Kit. Copyright, Bioneer Corporation. All rights reserved.
: AccuPower ZIKV(DENV, CHIKV) Multiplex Real-Time RT-PCR Kit Copyright, Bioneer Corporation. All rights reserved. 1. Offers superior diagnostic accuracy compared to immunoassay Allows precision diagnosis,
More informationZika. Nicole Evert, MS Zoonosis Control Branch Department of State Health Services Austin, Texas
Zika Nicole Evert, MS Zoonosis Control Branch Department of State Health Services Austin, Texas Family Flaviviridae, genus Flavivirus Vectors: Aedes aegypti and Aedes albopictus Maintained in a human-mosquito-human
More informationMosquito Control Matters
Mosquito Control Matters Gary Goodman General Manager Sacramento-Yolo Mosquito & Vector Control District Sacramento Yolo Mosquito & Vector Control District To provide safe, effective and economical mosquito
More informationWelcome All. Western Australia Oncology Menopause Endometriosis New Mothers
Welcome All Western Australia ZIKA VIRUS What s the latest? Dr Clay Golledge COUNTRIES WITH ONGOING ZIKA CIRCULATION American Samoa Curacao Guyana Nicaragua Tonga Barbados Dominican Republic Haiti Panama
More informationVector-Borne Diseases Update: Maricopa County
Vector-Borne Diseases Update: Maricopa County Craig Levy, Epizoologist, Office of Epidemiology WeArePublicHealth.org twitter.com/maricopahealth facebook.com/mcdph Emerging Arboviruses Zika Virus Chikungunya
More informationWaiting in the Wings: Emergence, Impact and Control of Mosquito-Borne Viruses
International Center for Enterprise Preparedness (InterCEP) Waiting in the Wings: Emergence, Impact and Control of Mosquito-Borne Viruses Web Forum On April 14, 2016, Kathryn A. Hanley, Professor in the
More informationMosquitoborne Viral Diseases
Mosquitoborne Viral Diseases Originally prepared by Tom J. Sidwa, D.V.M, M.P.H State Public Health Veterinarian Zoonosis Control Branch Manager Texas Department of State Health Services 1 AGENT Viruses
More informationZika Virus What Every Woman Needs to Know
Zika Virus What Every Woman Needs to Know Carrie L. Byington, MD The Jean and Thomas McMullin Professor and Dean of Medicine Senior Vice President Health Science Center Vice Chancellor for Health Services
More informationZIKA: is South Africa at risk? Lucille Blumberg National Institute for Communicable Diseases South Africa
ZIKA: is South Africa at risk? Lucille Blumberg National Institute for Communicable Diseases South Africa 18 th April 1947; Rhesus macaque (no 766) with fever Filtrable transmissable agent The absence
More informationZika Virus Outbreak & Zika Congenital Syndrome. Regional Situation and Response
Zika Virus Outbreak & Zika Congenital Syndrome Regional Situation and Response PAHO Regional Meeting on the IBP Initiative, 15 June 2016 Lima, Peru 2 ZIKV in the Americas Impact and Lessons Learned ZIKV
More informationUpdate on Transfusion- Transmitted Infectious Diseases
Update on Transfusion- Transmitted Infectious Diseases Scott Koepsell MD PhD Associate Professor University of Nebraska Medical Center I have no conflicts of interest to disclose. Global changes and the
More informationThe problem with TORCH screening
: Beyond TORCHeS TORCH or STORCH-a helpful mnemonic? Toxoplasma Other Rubella CMV HSV (HIV) Syphilis 3 The problem with TORCH screening TORCH-first proposed by Nahmias et.al. (Pediatr Res 1971) Toxo, Rubella,
More informationFocus. International #57. Dengue Fever, Chikungunya and the Zika Virus. Chikungunya
Dengue Fever, Chikungunya and the Zika Virus Arboviruses are a group of virus that can be transmitted between animals and humans, and they are common to humans and many vertebrates (mammals, birds, reptiles,
More informationCDC Responds to ZIKA Zika 101
CDC Responds to ZIKA Zika 101 Updated April 29, 2016 What is Zika virus disease (Zika)? Disease spread primarily through the bite of an Aedes species mosquito infected with Zika virus. Many people infected
More information3/29/2017. Zika in Northeast Ohio. Cuyahoga County Board of Health (CCBH)
Joe Lynch, RS, MPH Program Manager Environmental Public Health Cuyahoga County Board of Health Zika in Northeast Ohio Cuyahoga County Board of Health (CCBH) Take care of public health matters for over
More informationZika Virus: Epidemiology and Preparedness NH Emergency Preparedness Conference June 9, 2016
Zika Virus: Epidemiology and Preparedness NH Emergency Preparedness Conference June 9, 2016 Abigail Mathewson, DVM, MPH Surveillance Epidemiology Program Manager State Public Health Veterinarian Abigail.mathewson@dhhs.nh.gov
More informationMosquito Threats in LA County West Nile virus & Zika
Mosquito Threats in LA County West Nile virus & Zika The District at a Glance An independent special district formed under authority of the CA State Health and Safety Code Formed in 1952 and governed by
More informationTravel: Chikungunya, Zika,.. New worries
Travel: Chikungunya, Zika,.. New worries McGill Family Physician Refresher Course Dec 6, 2016 Makeda Semret, MD FRCP(C) Infectious Diseases/ Medical Microbiology Disclosures Funding from PHAC/CIHR/GSK/Novartis
More informationMosquito Control Update. Board of County Commissioners Work Session February 16, 2016
Mosquito Control Update Board of County Commissioners Work Session February 16, 2016 1 Presentation Overview Mosquito Control Division Mosquito-borne Diseases Control Techniques Outlook 2 Mosquito Control
More informationMODULE 3: Transmission
MODULE 3: Transmission Dengue Clinical Management Acknowledgements This curriculum was developed with technical assistance from the University of Malaya Medical Centre. Materials were contributed by the
More informationMosquito Threats in Burbank West Nile virus and Zika Update. Presented by Kelly Middleton, Director of Community Affairs
Mosquito Threats in Burbank West Nile virus and Zika Update Presented by Kelly Middleton, Director of Community Affairs The District at a Glance An independent special district formed under authority of
More informationZIKA PRESENTED BY DENNIS QUERTERMOUS, DIANNA HUNTER, MERCEDES RUTLEDGE, AND DRE'ANDRIA THOMPSON
ZIKA PRESENTED BY DENNIS QUERTERMOUS, DIANNA HUNTER, MERCEDES RUTLEDGE, AND DRE'ANDRIA THOMPSON ZIKA OVERVIEW Family: Flaviviridae Genus: Flavivirus Enveloped, single-stranded RNA virus First identified
More informationThe Zika Crisis: Where, What and USG/WHO? Brian R. Moyer BRMoyer & Associates, LLC Bedford, NH
2016 National Biotechnology Conference, Boston, May 18th The Zika Crisis: Where, What and USG/WHO? Brian R. Moyer BRMoyer & Associates, LLC Bedford, NH 03110 bmoyernh@gmail.com 2016 National Biotechnology
More informationFact Sheet. Zika Virus
Fact Sheet Zika Virus The following provides information on the use and containment of Zika virus (ZIKV). Investigators should use these guidelines as part of their risk assessment when planning experiments
More informationWest Nile Fever. F. Karup Pedersen 2012
F. Karup Pedersen 2012 West Nile virus first isolated 1937 in West Nile district, Uganda Japanese encephalitis reconvalescens serum could neutralize West Nile virus Virus antigenically related to Japanese
More informationEDUCATIONAL COMMENTARY ZIKA VIRUS
EDUCATIONAL COMMENTARY ZIKA VIRUS Educational commentary is provided through our affiliation with the American Society for Clinical Pathology (ASCP). To obtain FREE CME/CMLE credits, click on Earn CE Credits
More informationWhere is Yellow Fever found?
Yellow Fever Introduction Yellow Fever is an acute viral hemorrhagic disease transmitted by a female mosquito of the Aedes family (Aedes aegypti). Man and monkeys are the only reservoir for this virus.
More informationAs suggested by one fellow student, please consider the CDC's "Final Rules for Control of Communicable Diseases: Interstate and Foreign
As suggested by one fellow student, please consider the CDC's "Final Rules for Control of Communicable Diseases: Interstate and Foreign http://www.cdc.gov/quarantine/ aboutlawsregulationsquarantineisolatio
More information