Financing ART in low- and middleincome. Karl L. Dehne UNAIDS

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1 Financing ART in low- and middleincome countries Karl L. Dehne UNAIDS

2 Close the global resource gap by 2015 $6 billion annually, overall target (between $22 billion and $24 billion) Programmes must become more cost-effective and evidence-based and deliver better value for money Break the upward trajectory of costs through the efficient utilization of resources Simplify treatment regimens and delivery Integrate HIV programmes with the health system Support and strengthen existing financial mechanisms including the Global Fund and relevant UN organizations Expand voluntary and innovative financing mechanisms

3 People receiving antiretroviral therapy versus the 2015 target, low- and middle-income countries,

4 54% of all people eligible were receiving antiretroviral therapy in low- and middle-income countries in 2011 Legend Number of people eligible for antiretroviral therapy. Percentage receiving ART in Source: UNAIDS, 2012

5 US$ billions Total HIV investments continue to grow International assistance Domestic resources in lowand middle-income countries Total resources available, with estimated range Source: UNAIDS, 2012

6 AIDS Resources (US$ billion) Millions of people on ART Investments have been slower than ART roll-out AIDS Resources and Treatment scale-up Africa : AIDS investment Antiretroviral treatment Source: UNAIDS, WHO 2012

7 Allocation of HIV spending in LMIC Source: Global AIDS Response Progress Reporting country reports ( ).

8 Prices of first-line and second-line antiretroviral regimens for adults in low-income countries, FIRST-LINE REGIMENS SECOND-LINE REGIMENS Source: Global Price Reporting Mechanism, World Health Organization, 2012.

9 ARV prices Ukraine 2004 vs Zidovudine (AZT) Lamivudine (3TC) Zidovudine (AZT) plus Lamivudine (3TC) Stavudine (d4t) Evafirenz (EFV) Nevirapine (NNRTI), tabs Nelvinavir

10 Reduction in the annual cost of facility-level antiretroviral therapy, per person year, selected countries, 2006 to *PEPFAR is the United States President s Emergency Plan for AIDS Relief. CHAI is the Clinton Health Access Initiative. Sources: Ethiopia 2006: Menzies NA et al. The cost of providing comprehensive HIV treatment in PEPFAR-supported programs. AIDS, 2011, 25: Zambia 2006: Bollinger L, Adesina A. Review of available antiretroviral treatment costs, major cost drivers and potential efficiency gains. Internal report. Geneva, UNAIDS, South Africa 2006: Bollinger L, Adesina A. Review of available antiretroviral treatment costs, major cost drivers and potential efficiency gains. Internal report. Geneva, UNAIDS, Ethiopia, Zambia and South Africa CHAI data: Facility-based unit costing of antiretroviral treatment: a costing study from 161 representative facilities in Ethiopia, Malawi, Rwanda, South Africa and Zambia. New York, Clinton Health Access Initiative, in press.

11 Facility-level and total treatment costs per person per year in Zambia, 2009 Note: Total treatment costs include facility-level costs, finance and accounting, Human Resources management, procurement, quality assurance, inventory and supply control, data analysis, insurance, IT and telecommunication, laboratory support and community liaison. Facility-level treatment costs Total treatment costs Source: Elliott Marseille, Health Strategies International, personal communication, analysis of data from the Centre for Infectious Disease Research in Zambia, 2012.

12 Share of care and treatment expenditure originating from international assistance, last year reported Source: Global AIDS Response Progress Reporting country reports (most recent available).

13 Percentage of HIV treatment from international sources in Africa

14 Source of ART funding by type of epidemic

15 Source of ART financing by income level

16 UNAIDS advocacy for increased HIV financing Documentation and analysis of trends, including domestic increases Dialogue with Ministries of Finance AU roadmap GA event in July, with several pledges Exploration of new and innovative financing sources Meeting on sustainable financing later this week

17 Domestic spending for AIDS increased national ownership, reduced dependency % increase in domestic investments for national AIDS response between 2006 and 2011 in low- and middleincome countries.

18 Potential alternative sources of funding from country studies Additional government expenditure Zambia Kenya Namibia Botswana Lesotho Swaziland Burkina Faso Cameroun X X X X X X X X Public sector mainstreaming X X X X X X Private sector contributions X X X X X X X X Airline levy X X X X X Health insurance X X X X X X Dormant funds X AIDS bond X AIDS lottery X Income levy X Alcohol levy X Remittances X Mobile phone levy X X X New borrowing X X X X X 2011 Oxford Policy Management Ltd Internal filing codes, date, presenter

19 Investment needed for treatment, care and support (all LMIC) Current spending Investment needs estimated reported Investment framework estimates Source: UNAIDS estimates, 2012; Global AIDS Response Progress Reporting country reports (most recent available); Schwartländer, B., et al. Towards an improved investment approach for an effective response to HIV/AIDS. Lancet 2011; 377:

20 Conclusions Past Demand for ART and ARVs steadily increasing HLM treatment and funding targets largely on track Markets and demand Increasing funding base, potential further efficiency gains, affordable treatments Investment against agreed priorities, at low cost and with good results tends to be attractive Leadership WHO/UNAIDS making the case to invest in ART, setting global targets, advocacy, clinical guidelines and technical support

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22 Thank you for your attention

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