ALLERGIES ALLERGY. when the body treats a harmless substance as a threat and the immune system produces an unnecessary response. Trivial (nuisance)
|
|
- Raymond Ferguson
- 5 years ago
- Views:
Transcription
1 ALLERGY when the body treats a harmless substance as a threat and the immune system produces an unnecessary response Severity of Response Trivial (nuisance) Life altering Fatal (anaphylaxis) Hayfever diagnosed Food allergies diagnosed UK Hospital admissions 25% population in UK 1-2% adult population in UK % increase INTOLERANCE Does NOT involve immune system and so NO ANAPHYLAXSIS
2 Percentage of children with allergic rhinitis/ eczema trebled in last 30 years Allergic asthma Sinusitis Chronic urticaria Atopic dermatitis Food allergies Drugs Bee stings Peanut allergy affects 10 million worldwide and can be fatal Apparently greater increase in allergies in children and women 7-fold increase in hospital admissions in Europe
3 Stem Cell Cells of the Immune System White Blood Cells (leucocytes) Red Blood Cells (erythrocytes) days Platelets (thrombocytes) 7-8 days Eosinophils Basophils Neutrophils Innate Immunity Monocytes Macrophage s T Cells Cell-mediated Immunity Lymphocytes Acquired Immunity B Cells Antibody- mediated Immunity
4 Lymphoid Tissue of Immune System Tonsils Thymus Spleen G ut A ssociated L ymphoid T issue B- and T-cells enter lymphoid tissue and are activated by exposure to ANTIGENS
5 ANTIGEN Any substance that stimulates antibody formation. Antigens are usually proteins (bacteria, viruses) ALLERGEN A HARMLESS substance (antigen) that stimulates IgE formation Human antibodies are Y shaped immunoglobulin (Ig) proteins, produced by B-cells IgA Mucus membranes, tears, saliva COLOSTRUM 15% total human Ig IgD Function unclear 0.25% serum Ig IgM 1 st produced in infections (Spleen) IgG Main antibody 75% of Igs in blood IgE Anti parasitic worms & flukes; malaria 0.05% of Igs Concentrated in LUNGS & SKIN Immunoglobulin associated with allergy
6 Normal response to injury = INFLAMMATION Allergic response = EXCESSIVE INFLAMMATION Redness HISTAMINE Blood flow and vascular permeability Heat SWELLING Mast Cell Allergen induces IgE formation by B-cells attaches to mast cells Re-exposure to allergen causes IgE-primed mast cell to release histamine
7 Allergic asthma Sinusitis Allergic rhinitis Atopic / Contact dermatitis Drugs Insect (bee) stings Food Allergy Any food CAN be allergenic but 90% due to a few food types Peanuts, tree nuts, wheat, dairy, eggs, fish, shellfish, soy, sesame, mustard, celery Processed foods risk cross contamination during production or supply chain
8 Mild to moderate symptoms of food allergy include: Swelling of face, lips and/or eyes Hives or welts on the skin Severe symptoms (anaphylaxis) include: Difficult/noisy breathing Swelling of tongue Swelling/tightness in throat Difficulty talking and/or hoarse voice Wheeze or persistent cough Persistent dizziness and/or collapse Pale and floppy (in young children) In May 2016, take-away proprietor convicted of manslaughter, for failing to keep allergen out of meal
9 MILK COELIAC DISEASE Allergy Immune response to protein in milk (eg casein) SYSTEMIC EFFECTS Hives Swelling Respiratory Danger of anaphylaxisis Intolerance Lack of enzyme (lactase) to digest milk sugar (lactose) GI EFFECTS Nausea, Cramps, Gas/bloating Diarrhoea NO risk of anaphylaxis anaemia Gluten (protein in wheat, oats etc) links to own small intestine proteins AUTOIMMUNE RESPONSE osteoporosis Destruction of absorptive surface of small intestine Increased susceptibility to infections:- Pneumococcus Meningitis Thermophilus malnourishment
10 Possible causes of increase in allergies Hygiene Hypothesis Excessively clean homes remove learning experience for immune system Originated in 1970s Comparison of allergy rates in 100 urban children (50%) vs 100 Amish children (7%) Recent research: Increase not related to ANY MICROBES MIGHT be related to reduced RANGE of microbes ( old friends ) SANITATION clean water remove bacterial diseases such as typhoid, cholera Remove parasites such as helminth worms, flukes, plasmodium (malaria), schistosoma Natural target of IgE Parasite survival strategy = damp down immune system response Removing exposure to parasites has removed natural controller of IgE
11 Other explanations of increase in allergies Genetic predisposition (familial) [>70 genes identified in food allergies] PLUS epigenetic factors eg pollutants switching genes on / off Vitamin D Vital for calcium absorption, bone formation, growth repair (rickets, osteomalacia) Also involved with lung development - dampening antibody related immunity - diminishing inflammation Mostly made in skin with exposure to sunlight (needs activation in liver) Less time out of doors Use of sunscreens (skin cancer!) Skin creams/cosmetics containing allergens eg nut oils viz onto broken skin/eczema
12 Other explanations of increase in allergies FOOD LEAP & LEAP-ON studies Inclusion of allergenic foods in early days Exclusion of allergenic foods in early days 320 avoid peanuts 640 at risk infants 320 eat peanut snacks 3x/wk CHINA peanuts widely consumed but allergy rare. Peanuts are boiled so proteins clumped GALT US peanuts widely consumed and allergy common. Peanuts are dry roast so proteins fragmented NOT an explanation for other food allergies Age 5 54 (17%) allergic 556 continued 10 (3%) allergic avoiders consumers 12 months avoiding peanuts 71 (18.6%) allergic 13 (4.8%) allergic resistance to allergy persists
13 Other explanations of increase in allergies Vaccinations? Germany: Preunification had compulsory vaccination and low allergy levels Post unification (1990), immunisation NOT compulsory allergy increasing Antibiotics? Early use predisposes to asthma? Cause damage to gut biota. DYSBIOSIS = microbial imbalance or maladaptation on or inside body Obesity!! Climate Change Increased CO 2 traps more pollen (&/or modifies pollen to be allergenic) particulates etc
14 Diagnosis Skin prick test results in 20mins Patch test 48h exposure Blood test Assess allergen specific IgE Assess total IgE levels but high levels also occur with parasites Assess eosinophils (antiworms /parasites) but levels can be raised with no allergy and low with allergy
15 Treatment Desensitise using immunotherapy Give minute amounts of allergen; recent results promising ( reputation dogged by poor practice in 1970's Biologist 63(3) p31 Epipen = adrenalin aka epinephrine Prevention better than cure!!
16 Some outstanding questions Why does allergy occur? Why is response in some sensitised individuals mild but severe in others? Why does intensity of response vary wildly in same individual? What governs familial traits?
17 Some of websites used Wikipedia! American Association of Allergy & Asthma Royal Society of Biology AllergyUK Foodallergy.org Sciencedaily Medicinenet.com Shutterstock & Getty Images BBC.co.uk/news
Path2220 INTRODUCTION TO HUMAN DISEASE ALLERGY. Dr. Erika Bosio
Path2220 INTRODUCTION TO HUMAN DISEASE ALLERGY Dr. Erika Bosio Research Fellow Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research University of Western Australia
More informationBody Defense Mechanisms
BIOLOGY OF HUMANS Concepts, Applications, and Issues Fifth Edition Judith Goodenough Betty McGuire 13 Body Defense Mechanisms Lecture Presentation Anne Gasc Hawaii Pacific University and University of
More informationFood Allergy , The Patient Education Institute, Inc. imf10101 Last reviewed: 10/15/2017 1
Food Allergy Introduction A food allergy is an abnormal response to a food. It is triggered by your body's immune system. An allergic reaction to a food can sometimes cause severe illness or death. Tree
More information1
1 2 3 4 5 6 Scratch and Sniff All About Allergies Doug Jones, MD Program Director, Family Medicine, DHMG What is an allergic reaction? The immune system identifies things that are foreign and protects
More informationFirst Aid Information
ISSUED May 2018 First Aid Information First Aid Kits Are Located: First Aid Kits Are Managed By: First Aid Kits Are Accessible By: Church Staff Ministry Volunteer Leaders Ministry Volunteer Team Members
More informationAllergies & Hypersensitivies
Allergies & Hypersensitivies Type I Hypersensitivity: Immediate Hypersensitivity Mediated by IgE and mast cells Reactions: Allergic rhinitis (hay fever) Pollens (ragweed, trees, grasses), dust mite feces
More informationBlood and Immune system Acquired Immunity
Blood and Immune system Acquired Immunity Immunity Acquired (Adaptive) Immunity Defensive mechanisms include : 1) Innate immunity (Natural or Non specific) 2) Acquired immunity (Adaptive or Specific) Cell-mediated
More informationAllergy Glossary of Terms
Adrenaline (Epinephrine) Allergy Glossary of Terms Adrenaline is a natural hormone released in response to stress. When injected, adrenaline rapidly reverses the effects of a severe allergic reaction (anaphylaxis)
More informationEczema: also called atopic dermatitis; a chronic, itchy, scaly rash not due to a particular substance exposure
Allergy is a condition in which the immune system causes sneezing, itching, rashes, and wheezing, or sometimes even life-threatening allergic reactions. The more you know about allergies, the better prepared
More informationFood Allergens. Food Allergy. A Patient s Guide
Food Allergens Food Allergy A Patient s Guide Food allergy is an abnormal response to a food triggered by your body s immune system. About 3 percent of children and 1 percent of adults have food allergy.
More informationFood allergens: Challenges for risk assessment
Food allergens: Challenges for risk assessment Stefano Luccioli, MD Office of Food Additive Safety Center for Food Safety and Applied Nutrition Goals Introduce food allergy Describe challenges for risk
More informationAllergy Management Policy
Allergy Management Policy Food Allergy People with allergies have over-reactive immune systems that target otherwise harmless elements of our diet and environment. During an allergic reaction to food,
More informationChapter 23 Immunity Exam Study Questions
Chapter 23 Immunity Exam Study Questions 1. Define 1) Immunity 2) Neutrophils 3) Macrophage 4) Epitopes 5) Interferon 6) Complement system 7) Histamine 8) Mast cells 9) Antigen 10) Antigens receptors 11)
More informationYVONNE POLYDOROU PAEDIATRIC ALLERGY SPECIALIST DIETITIAN
YVONNE POLYDOROU PAEDIATRIC ALLERGY SPECIALIST DIETITIAN 08-12-2016 An allergy is the response of the body's immune system to normally harmless substances, such as pollens, foods, and house dust mite.
More informationPaediatric Food Allergy. Introduction to the Causes and Management
Paediatric Food Allergy Introduction to the Causes and Management Allergic Reactions in Children Prevalence of atopic disorders in urbanized societies has increased significantly over the past several
More informationEPIPEN INSERVICE Emergency Administration of Epinephrine for the Basic EMT. Michael J. Calice MD, FACEP St. Mary Mercy Hospital
EPIPEN INSERVICE Emergency Administration of Epinephrine for the Basic EMT Michael J. Calice MD, FACEP St. Mary Mercy Hospital Case #1 NR is an 8 yo male c/o hot mouth and stomach ache after eating jelly
More informationMyth: Prior Episodes Predict Future Reactions REALITY: No predictable pattern Severity depends on: Sensitivity of the individual Dose of the allergen
Myth: Prior Episodes Predict Future Reactions REALITY: No predictable pattern Severity depends on: Sensitivity of the individual Dose of the allergen Anaphylaxis Fatalities Estimated 500 1000 deaths annually
More informationAllergy Skin Prick Testing
Allergy Skin Prick Testing What is allergy? The term allergy is often applied erroneously to a variety of symptoms induced by exposure to a wide range of environmental or ingested agents. True allergy
More informationImmunology. Lecture- 8
Immunology Lecture- 8 Immunological Disorders Immunodeficiency Autoimmune Disease Hypersensitivities Immunodeficiency 1. Immunodeficiency --> abnormal production or function of immune cells, phagocytes,
More informationAnaphylaxis Management Policy
Moe (South Street) Primary School 4662 Positivity, Accountability, Respect, Teamwork Anaphylaxis Management Policy 1. Rationale or Purpose Anaphylaxis is a severe, rapidly progressive allergic reaction
More informationCells of the Immune System. White Blood Cells Phagocytes - Neutrophils - Macrophages Lymphocytes
THE IMMUNE SYSTEM Blood Cells Cells of the Immune System White Blood Cells Phagocytes - Neutrophils - Macrophages Lymphocytes Phagocytes Produced throughout life by the bone marrow. Scavengers remove dead
More informationFaith Lutheran College, Redlands Faith in Christ prepared for life A I ANAPHYLAXIS POLICY T H. Last updated June 2017
F Faith Lutheran College, Redlands Faith in Christ prepared for life A I ANAPHYLAXIS POLICY T H Last updated June 2017 Food Allergy Policy and Procedures Rationale: Within the general community, there
More informationFDA/NSTA Web Seminar: Teach Science Concepts and Inquiry with Food
LIVE INTERACTIVE LEARNING @ YOUR DESKTOP FDA/NSTA Web Seminar: Teach Science Concepts and Inquiry with Food Thursday, November 15, 2007 Food allergy Stefano Luccioli, MD Office of Food Additive Safety
More informationHealth Point: Understanding Allergic Reactions
Health Point: Understanding Allergic Reactions What are allergies? Every person s body is different. People s bodies can react differently to the same things. For example, you may like to eat fish, but
More informationAllergies. Allergy. "Céad míle fáilte romhainn agus Lá. Fhéile Pádraig Sona Daoibh"
Allergies Why More Common? New Manifestations Management Options Dr. Robert Schellenberg, MD, FRCPC Dr. Amin Kanani, MD, FRCPC Dr. Donald Stark, MD, FRCPC "Céad míle fáilte romhainn agus Lá Fhéile Pádraig
More informationMMO CLINIC MAYO CLINIC
MMO CLINIC Overview Allergies occur when your immune system reacts to a foreign substance such as pollen, bee venom or pet dander or to a food that doesn't cause a reaction in most people. Your immune
More informationGET TRAINED. What Would You Do? You have moments to react. Bianca 1/15/2014 GET TRAINED
GET TRAINED It s time to GET TRAINED to administer an epinephrine auto-injector in an emergency! What Would You Do? Bianca has a bee sting allergy She is playing in the garden at her friends house She
More informationfirst aid information
first aid information FIRST AID TREATMENT FOR ANAPHYLAXIS Anaphylaxis is a severe allergic reaction and potentially life threatening. It should always be treated as a medical emergency, requiring immediate
More informationALLERGY AWARENESS POLICY
ALLERGY AWARENESS POLICY 1. RATIONALE Allergies are very common and increasing in Australia and New Zealand, affecting around 1 in 5 people at some time in their lives. There are many different causes
More informationFeed those babies some peanut products!!!
Disclosures Feed those babies some peanut products!!! No relevant disclosures Edward Brooks Case presentation 5 month old male with severe eczema starting at 3 months of age. He was breast fed exclusively
More informationPediatric Allergy Allergy Related Testing
Pediatric Allergy Allergy Related Testing 1 Allergies are reactions that are usually caused by an overactive immune system. These reactions can occur in a variety of organs in the body, resulting in conditions
More informationFood-allergy-FINAL.mp3. Duration: 0:07:39 START AUDIO
BMJ LEARNING VIDEO TRANSCRIPT File: Duration: 0:07:39 Food-allergy-FINAL.mp3 START AUDIO Adam Fox: Food allergy is an inappropriate immune response to food. Our immune systems should ignore food completely,
More informationGlossary of Terms ASCIA EDUCATION RESOURCES (AER) PATIENT INFORMATION
Glossary of Terms Allergen A substance which can cause an allergic reaction. Allergen Immunotherapy A series of injections (shots) or sublingual drops are administered which contain the allergen such as
More informationADVANCED DIPLOMA IN PRINCIPLES OF NUTRITION
ADVANCED DIPLOMA IN PRINCIPLES OF NUTRITION BY LAUREN OWENS RD BSC (HONS) Human Nutrition and DIetetics Course Educators: Thomas Woods, William Eames BY LAUREN OWENS @ShawPhotoTom Special Diets Semester
More informationChapter 24 The Immune System
Chapter 24 The Immune System The Immune System Layered defense system The skin and chemical barriers The innate and adaptive immune systems Immunity The body s ability to recognize and destroy specific
More informationFood allergy in children. nice bulletin. NICE Bulletin Food Allergy in Chlidren.indd 1
nice bulletin Food allergy in children NICE provided the content for this booklet which is independent of any company or product advertised NICE Bulletin Food Allergy in Chlidren.indd 1 23/01/2012 11:04
More informationCLINICAL TOOLKIT. For interactive versions, v isit our website: AllergyEducation.co.uk. Job code: TFSUK1665. Date of preparation: June 2016.
CLINICAL TOOLKIT For interactive versions, v isit our website: AllergyEducation.co.uk Job code: TFSUK1665. Date of preparation: June 2016. DIAGNOSING ALLERGY - 1,2,3 Step 1: Take a history Diagnosing allergy
More informationRand E. Dankner, M.D. Jacqueline L. Reiss, M. D.
Tips to Remember: Food allergy Up to 2 million, or 8%, of children, and 2% of adults in the United States are estimated to have food allergies. With a true food allergy, an individual's immune system will
More informationAllergy overview. Mike Levin Division of Asthma and Allergy Department of Paediatrics University of Cape Town Red Cross Hospital
Allergy overview Mike Levin Division of Asthma and Allergy Department of Paediatrics University of Cape Town Red Cross Hospital Adaptive Immune Responses Adaptive immune responses allow responses against
More informationB cell response. B cell response. Immunological memory from vaccines. Macrophage and helper T cell involvement with initiating a B cell response:
B cell response Macrophage and helper T cell involvement with initiating a B cell response: B cell response When specific B cells are activated, they multiply Some cells become memory cells, stored in
More informationMichaela Lucas. Clinical Immunologist/Immunopathologist. Pathwest, QE2 Medical Centre, Princess Margaret Hospital
Michaela Lucas Clinical Immunologist/Immunopathologist Pathwest, QE2 Medical Centre, Princess Margaret Hospital School of Medicine and Pharmacology, School of Pathology and Laboratory Medicine University
More informationImmune System.notebook March 07, Maintaining Dynamic Equilibrium. Immune system 1st, 2nd and 3rd line of defense Immune disorders
Unit 3 Maintaining Dynamic Equilibrium Immune system 1st, 2nd and 3rd line of defense Immune disorders Oct 11 3:27 PM p.382 386 Immune system A complex system involving several organs and tissues (e.g.
More informationSt. Joseph s Primary School Numurkah
St. Joseph s Primary School Numurkah Anaphylaxis Procedure March 2014 Basic Beliefs: Our school community nurtures the development of the whole child. Our School is built on respect and an appreciation
More informationAllergy 101. Lori Connors, MD, MEd, FRCPC Allergy and Clinical Immunology. Dalhousie University Mini Medical School Oct 19, 2017
Allergy 101 Lori Connors, MD, MEd, FRCPC Allergy and Clinical Immunology Dalhousie University Mini Medical School Oct 19, 2017 Objectives By the end of this talk participants will be able to: Define allergy
More information4/28/2016. Host Defenses. Unit 8 Microorganisms & The Immune System. Types of Innate Defenses. Defensive Cells Leukocytes
Host Defenses Unit 8 Microorganisms & The Immune System CH 16-18 Host defenses that produce resistance can be either innate or adaptive: Innate: those that protect against any type of invading agent Adaptive:
More informationAllergy Awareness & EpiPen Administration
Allergy Awareness & EpiPen Administration 2017-18 Common Allergens in Children! Shellfish! Milk! Egg! Peanut! Tree Nuts! Fish! Soy! Latex! Insect Stings! Exercise What is an allergy? * An allergy is an
More informationManaging Allergies and Anaphylaxis at School EPI-PEN TRAINING FOR SCHOOL PERSONNEL
Managing Allergies and Anaphylaxis at School EPI-PEN TRAINING FOR SCHOOL PERSONNEL Objective: Attendees will be able to: Increase their knowledge about allergies to food and other allergens. Describe the
More informationANAPHYLAXIS POLICY & PROCEDURES
PHOENIX P-12 COMMUNITY COLLEGE ANAPHYLAXIS POLICY & PROCEDURES Policy Statement Anaphylaxis is a severe, rapidly progressive allergic reaction that involves various areas of the body simultaneously and
More informationAn allergic reaction is an exaggerated response by the immune system to a foreign substance
ALLERGIC REACTION An allergic reaction is an exaggerated response by the immune system to a foreign substance Anaphylaxis is an unusual or exaggerated allergic reaction; is a life threatening emergency
More informationWhat is allergy? Know your specific IgE
What is allergy? What is allergy? Know your specific IgE Allergies are very common and increasing in Australia and New Zealand, affecting around one in three people at some time in their lives. There are
More informationMurrayville Community College Anaphylaxis Policy
PURPOSE To explain to Murrayville Community College parents, carers, staff and students the processes and procedures in place to support students diagnosed as being at risk of suffering from anaphylaxis.
More informationUrticaria Moderate Allergic Reaction Mild signs/symptoms with any of following: Dyspnea, possibly with wheezes Angioneurotic edema Systemic, not local
Allergic Reactions & Anaphylaxis Incidence In USA - 400 to 800 deaths/year Parenterally administered penicillin accounts for 100 to 500 deaths per year Hymenoptera stings account for 40 to 100 deaths per
More informationCranbourne West Primary School No ANAPHYLAXIS MANAGEMENT POLICY
Draft: 9 Date: 30/5/16 Ratified: 6/6/16 Cranbourne West Primary School No. 5189 ANAPHYLAXIS MANAGEMENT POLICY RATIONALE/GENERAL STATEMENT Anaphylaxis is a severe, rapidly progressive allergic reaction
More informationAllergy Management Policy
Overview Allergy Management Policy This policy is concerned with a whole school approach to the health care and management for members of the school community. Rationale The intent of this policy is to
More informationPage # Lecture 8: Immune Dysfunction - Immunopathology. Four Types of Hypersensitivity. Friend of Foe? Autoimmune disease Immunodeficiency
Lecture 8: Immune Dysfunction - Immunopathology Autoimmune disease Immunodeficiency Allergy and Asthma Graft rejection and Lupus Friend of Foe? Four Types of Hypersensitivity Allergic Responses - Type
More informationDefense & the Immune System. Immune System Agenda 4/28/2010. Overview. The bigger picture Non specific defenses Specific defenses (Immunity)
Defense &The Immune System Overview Immune System Agenda The bigger picture Non specific defenses Specific defenses (Immunity) Defense & the Immune System Big Picture Defense Any means of preventing or
More informationManagement of ANAPHYLAXIS in the School Setting. Updated September 2010
Management of ANAPHYLAXIS in the School Setting Updated September 2010 What is an Allergy? Allergies occur when the immune system becomes unusually sensitive and over reacts to common substance that are
More informationINNATE IMMUNITY Non-Specific Immune Response. Physiology Unit 3
INNATE IMMUNITY Non-Specific Immune Response Physiology Unit 3 Protection Against Infection The body has several defenses to protect itself from getting an infection Skin Mucus membranes Serous membranes
More informationFACTSHEET ALLERGY. What is an allergy? HELPLINE: website: Page 1
Allergic disorders are on the increase in the UK and across the world, affecting up to 40% of the population. Allergic disorders include food allergy, eczema, asthma and allergic rhinitis (commonly known
More informationTerms What is Anaphylaxis? Causes Signs & Symptoms Management Education Pictures Citations. Anaphylaxis; LBodak
Leslie Bodak, EMT-P Terms What is Anaphylaxis? Causes Signs & Symptoms Management Education Pictures Citations Allergic Reaction: an abnormal immune response the body develops when a person has been previously
More informationI. Lines of Defense Pathogen: Table 1: Types of Immune Mechanisms. Table 2: Innate Immunity: First Lines of Defense
I. Lines of Defense Pathogen: Table 1: Types of Immune Mechanisms Table 2: Innate Immunity: First Lines of Defense Innate Immunity involves nonspecific physical & chemical barriers that are adapted for
More informationImmune system. Aims. Immune system. Lymphatic organs. Inflammation. Natural immune system. Adaptive immune system
Aims Immune system Lymphatic organs Inflammation Natural immune system Adaptive immune system Major histocompatibility complex (MHC) Disorders of the immune system 1 2 Immune system Lymphoid organs Immune
More informationACTION PLAN FOR. Difficult/noisy breathing Swelling of tongue Swelling/tightness in throat Wheeze or persistent cough ACTION FOR ANAPHYLAXIS
www.allergy.org.au Name: Date of birth: Photo Confirmed allergens: Family/emergency contact name(s): ACTION PLAN FOR Anaphylaxis SIGNS OF MILD TO MODERATE ALLERGIC REACTION Swelling of lips, face, eyes
More informationAll animals have innate immunity, a defense active immediately upon infection Vertebrates also have adaptive immunity
1 2 3 4 5 6 7 8 9 The Immune System All animals have innate immunity, a defense active immediately upon infection Vertebrates also have adaptive immunity Figure 43.2 In innate immunity, recognition and
More informationRecognition & Management of Anaphylaxis in the Community. S. Shahzad Mustafa, MD, FAAAAI
Recognition & Management of Anaphylaxis in the Community S. Shahzad Mustafa, MD, FAAAAI Disclosures None Outline Define anaphylaxis Pathophysiology Common causes Recognition and Management Definition Acute,
More informationGrading: Allergies. Course Overview. Allergy. Basic Terms. Most Common Allergenic Foods
Grading: Allergies Instructor: Andrea Bartels B.A. NNCP RNT Session #2 of 5: Quiz: 20% Session #5 of 5: Final test: 60% (all-inclusive) Assignment: 20% (TBA) Course Overview Different types of hyper-sensitivities
More informationCampbell's Biology: Concepts and Connections, 7e (Reece et al.) Chapter 24 The Immune System Multiple-Choice Questions
Campbell's Biology: Concepts and Connections, 7e (Reece et al.) Chapter 24 The Immune System 24.1 Multiple-Choice Questions 1) The body's innate defenses against infection include A) several nonspecific
More information2. The normal of the gut, and vagina keep the growth of pathogens in check. 3. in the respiratory tract sweep out bacteria and particles.
Chapter 39 Immunity I. Three Lines of Defense A. Surface Barriers to Invasion 1. is an important barrier. 2. The normal of the gut, and vagina keep the growth of pathogens in check. 3. in the respiratory
More informationGreythorn Primary School Anaphylaxis Management Policy
Greythorn Primary School Anaphylaxis Management Policy Purpose: It is the school s responsibility to consider the Health and Wellbeing of all students. To facilitate the safety of students diagnosed with
More informationLYMPHATIC AND IMMUNE SYSTEMS. Chapter 33
LYMPHATIC AND IMMUNE SYSTEMS Chapter 33 THE LYMPHATIC SYSTEM The lymphatic system has three main functions Take up excess tissue fluid and return it to the bloodstream Receive fats called lipoproteins
More informationSouthern Derbyshire Shared Care Pathology Guidelines. Allergy Testing in Adults
Southern Derbyshire Shared Care Pathology Guidelines Allergy Testing in Adults Allergy Tests are not diagnostic of Allergy Purpose of Guideline How to obtain an allergy-focussed clinical history When allergy
More informationTopics in Parasitology BLY Vertebrate Immune System
Topics in Parasitology BLY 533-2008 Vertebrate Immune System V. Vertebrate Immune System A. Non-specific defenses against pathogens 1. Skin - physical barrier a. Tough armor protein KERATIN b. Surface
More informationANAPHYLAXIS POLICY Clifton Hill Primary School 2018
ANAPHYLAXIS POLICY Clifton Hill Primary School 2018 BACKGROUND Anaphylaxis is a severe, rapidly progressive allergic reaction that is potentially life threatening. The most common allergens in school-aged
More informationLymphatic System. Where s your immunity idol?
Lymphatic System Where s your immunity idol? Functions of the Lymphatic System Fluid Balance Drains excess fluid from tissues Lymph contains solutes from plasma Fat Absorption Lymphatic system absorbs
More informationFood allergies and eczema
Department of Dermatology Food allergies and eczema Information for parents and carers Eczema, also known as atopic eczema or atopic dermatitis, is a skin condition that causes inflammation and irritation.
More informationFAUQUIER COUNTY PUBLIC SCHOOLS Policy: Adopted: 04/10/2012 Revised: 07/23/12, 7/08/13, 08/11/14, 08/14/17 ADMINISTERING MEDICINES TO STUDENTS
ACCOMPANYING REGULATION REGULATION 7-5.3(B): ADMINISTRATION OF EPINEPHRINE (Severe Allergic Reaction) 1. Generally 1.1. Fauquier County Public Schools Public Schools ( FCPS) anaphylaxis regulation is developed
More informationAnaphylaxis Policy. Rationale. What is anaphylaxis?
Anaphylaxis Policy Rationale Allergic reactions are common in children. However, severe life threatening allergic reactions are uncommon and deaths are rare. Protecting our community from the effects of
More informationFood Allergy I. William Reisacher, MD FACS FAAOA Department of Otorhinolaryngology Weill Cornell Medical College
Food Allergy I William Reisacher, MD FACS FAAOA Department of Otorhinolaryngology Weill Cornell Medical College History of Food Allergy Old Testament - Hebrews place dietary restrictions in order to prevent
More informationImmunocompetence The immune system responds appropriately to a foreign stimulus
Functions of the immune system Protect the body s internal environment against invading organisms Maintain homeostasis by removing damaged cells from the circulation Serve as a surveillance network for
More informationEpiPen Training Module:
EpiPen Training Module: Managing Life Threatening Allergies Chelmsford Public Schools September, 2016 Purpose To provide basic knowledge and skill to unlicensed school personnel to administer epinephrine
More informationHow will we manage food allergy in 2026
How will we manage food allergy in 2026 Paul Turner MRC Clinician Scientist & Honorary Consultant in Paediatric Allergy & Immunology, Imperial College London; Honorary Clinical Lecturer, University of
More informationALLERGIES ARE A LOW PROFILE HIGH IMPACT DISEASE. MASOOD AHMAD,M.D.
ALLERGIES ARE A LOW PROFILE HIGH IMPACT DISEASE. MASOOD AHMAD,M.D. What Is a Food Allergy? A food allergy is a medical condition in which exposure to a food triggers an IgE mediated immune response. The
More informationInternal Defense Notes
Internal environment of animals provides attractive area for growth of bacteria, viruses, fungi Harm via: 1. destruction of cells 2. production of toxic chemicals To protect against foreign invaders, humans
More informationChapter Pages Transmission
Chapter 19.2 Pages 442-448 Transmission Immunity There are three lines of defense: 1 The skin and mucous membranes are a nonspecific barrier to infection. 2 Macrophages attack pathogens that enter the
More informationAbout the immune system
The immune system and anaphylaxis edward.purssell@kcl.ac.uk About the immune system The immune system Protects the body from infectious organisms, foreign bodies and malignancies Surface barriers Innate
More informationHypersensitivity diseases
Hypersensitivity diseases Downloaded from: StudentConsult (on 18 July 2006 11:40 AM) 2005 Elsevier Type-I Hypersensitivity Basic terms Type-I = Early= IgE-mediated = Atopic = Anaphylactic type of hypersensitivity
More informationCCSD School Nurses. Support of Students with Life Threatening Allergies
CCSD School Nurses Support of Students with Life Threatening Allergies The Clark County School District is committed to provide a safe, supportive environment in which all students can learn and achieve.
More information3/28/2012. Immune System. Activation of Innate Immunity. Innate (non-specific) Immunity
Chapter 5 Outline Defense Mechansims Functions of B Lymphocytes Functions of T Lymphocytes Active and Passive Immunity Tumor Immunology Diseases Caused By Immune System Immune System Anatomy - Lymphoid
More informationAP Biology. Why an immune system? Chapter 43. Immune System. Lines of defense. 1st: External defense. 2nd: Internal, broad range patrol
Chapter 43. Immune System lymphocytes attacking cancer cell lymph phagocytic leukocyte Why an immune system? Attack from outside lots of organisms want you for lunch! animals must defend themselves against
More informationUnit 3 Dynamic Equilibrium Chapter Immune System
Biology 2201 Unit 3 Dynamic Equilibrium Chapter 11.4 - Immune System Compiled by S. Whalen What is Immunity? Immunity Immunity The ability of the body to fight infection and/or foreign invaders by producing
More informationANAPHYLAXIS POLICY. Purpose of this policy. Guidelines
Purpose of this policy ANAPHYLAXIS POLICY To ensure schools manage students at risk of anaphylaxis and meet legislative requirements. To provide, as far as practicable, a safe and supportive environment
More informationAllergic rhinitis (Hay fever) Asthma Anaphylaxis Urticaria Atopic dermatitis
Hypersensitivity Disorders Hypersensitivity Disorders Immune Response IgE Disease Example Ragweed hay fever IgG Cytotoxic Immune complex T Cell Hemolytic anemia Serum sickness Poison ivy IgE-mediated Diseases
More informationNEWSLETTER NINETEENTH EDITION APRIL 2014 ALLSA REPORT FROM THE CHAIRMAN INSIDE THIS ISSUE APRIL 2014 NINETEENTH EDITION 1. My Dear Colleagues
NEWSLETTER NINETEENTH EDITION APRIL 2014 ALLSA REPORT FROM THE CHAIRMAN My Dear Colleagues April sees us sharing World Allergy Week along with the World Allergy Organisation. This year we chose to add
More informationImmune System. Presented by Kazzandra Anton, Rhea Chung, Lea Sado, and Raymond Tanaka
Immune System Presented by Kazzandra Anton, Rhea Chung, Lea Sado, and Raymond Tanaka Content Standards 35.1 In innate immunity, recognition and response rely on traits common to groups of pathogens 35.2
More informationANAPHYLAXIS MANAGEMENT POLICY
ANAPHYLAXIS MANAGEMENT POLICY PHILOSOPHY The management of Anaphylaxis, a severe, rapidly progressive allergic reaction that is potentially life threatening, is an essential component of Mount Waverley
More informationAnaphylaxis Management
Williamstown Primary School Anaphylaxis Management 1. BACKGROUND Anaphylaxis is a serious health issue for a percentage of the population and the Department recognises the key to preventing an anaphylactic
More informationELWOOD COLLEGE PROGRAM: ANAPHYLAXIS MANAGEMENT POLICY NO: 4 DATE: 09/02/10
ELWOOD COLLEGE Glenhuntly Rd, Elwood, 3184, Telephone 9531 9566 PROGRAM: ANAPHYLAXIS MANAGEMENT POLICY NO: 4 DATE: 09/02/10 PURPOSE: 1. To provide, as far as practicable, a safe school environment in which
More informationAilléirge Péidiatraiceach. Pediatric Allergy 3/9/2018. Disclosures & Conflicts Of Interest
Ailléirge Péidiatraiceach Michael Zacharisen, M.D. Allergy/Immunology Pediatric Allergy Michael Zacharisen, M.D. Allergy/Immunology Disclosures & Conflicts Of Interest Green Bay Packer fan I drive a Jeep
More informationMONTGOMERY COUNTY COMMUNITY COLLEGE Department of Science LECTURE OUTLINE CHAPTERS 16, 17, 18 AND 19
MONTGOMERY COUNTY COMMUNITY COLLEGE Department of Science LECTURE OUTLINE CHAPTERS 16, 17, 18 AND 19 CHAPTER 16: NONSPECIFIC DEFENSES OF THE HOST I. THE FIRST LINE OF DEFENSE A. Mechanical Barriers (Physical
More informationFood Allergies BACKGROUND SCENARIO BIOTECHNOLOGY LAB. Name Period Date
BIOTECHNOLOGY LAB Food Allergies BACKGROUND Sometimes Jamie's younger brother Andrew complains that his stomach hurts and he might vomit his food. Other times he breaks out in hives all over his body.
More information