Publication Dr. Simon Blank
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1 Publication Dr. Simon Blank IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology.matthias van Vaerenbergh, Lina de Smet, David Rafei-Shamsabadi, Simon Blank, Edzard Spillner, Didier Ebo, Bart Devreese, Thilo Jakob, Dirk C. de Graaf Molecular Immunology, in press (2014) 32 Basophil activation test using recombinant allergens: highly specific diagnostic method complementing routine tests in wasp venom allergy. Lukas Balzer, Davide Pennino, Simon Blank, Henning Seismann, Ulf Darsow, Mathias Schnedler, Mareike McIntyre, Markus Ollert, Steven R. Durham, Edzard Spillner, Johannes Ring, and Liliana Cifuentes PLOS ONE, in press (2014) 31 Reply to: Recombinant allergens rarely allow identification of Hymenoptera venomallergic patients with negative specific IgE to whole venom preparations. Liliana Cifuentes, Simon Blank, Davide Pennino, Jana Michel, Ulf Darsow, Johannes Ring, and Markus Ollert Journal of Allergy and Clinical Immunology, 134(2): (2014) 30 Hymenoptera Allergens: From Venom to Venome. Edzard Spillner, Simon Blank, Thilo Jakob Frontiers in Immunology, 5:77 (2014) 29 Component resolution reveals additional major allergens in patients with honeybee venom allergy. Julian Köhler, Simon Blank, Sabine Müller, Frank Bantleon, Marcel Frick, Johannes Huss- Marp, Jonas Lidholm, Edzard Spillner, and Thilo Jakob Journal of Allergy and Clinical Immunology, 133 (5): (2014). 28 Identification of hymenoptera venom-allergic patients with negative specific IgE to venom extract by using recombinant allergens. Liliana Cifuentes, Sebastian Vosseler, Simon Blank, Henning Seismann, Thomas Grunwald, Ulf Darsow, Reinhard Bredehorst, Martin Mempel, Edzard Spillner, Johannes Ring, and Markus Ollert Journal of Allergy and Clinical Immunology, 133 (3): (2014). 1
2 Donor Assists Acceptor Binding and Catalysis of Human alpha1,6-fucosyltransferase. Miriam P. Kötzler, Simon Blank, Frank I. Bantleon, Martin Wienke, Edzard Spillner, and Bernd Meyer ACS Chemical Biology, 8 (8): (2013). 26 Vitellogenins are new high molecular weight components and allergens (Api m 12 and Ves v 6) of Apis mellifera and Vespula vulgaris venom. Simon Blank, Henning Seismann, Mareike McIntyre, Markus Ollert, Frank I. Bantleon, and Edzard Spillner PLOS ONE, 8(4):e62009 (2013). 25 Polistes species venom is devoid of carbohydrate-based cross-reactivity and allows interference free diagnostics. Simon Blank, Charles Neu, Daniel Hasche, Frank I. Bantleon, Thilo Jakob, and Edzard Spillner Journal of Allergy and Clinical Immunology, 131 (4): (2013). 24 Extending the honeybee venome with the antimicrobial peptide apidaecin and a protein resembling wasp antigen 5. Matthias van Vaerenbergh, Dries Cardoen, Ellen Formesyn, Marleen Brunain, Gonzalez van Driessche, Simon Blank, Edzard Spillner, Peter Verleyen, Tom Wenseleers, Liliane Schoofs, Bart Devreese, and Dirk de Graaf Insect Molecular Biology, 22 (2): (2013) An IgE epitope of Bet v 1 and fagales PR10 proteins as defined by a human monoclonal IgE. Julia Hecker, Andrea Diethers, Daniela Schulz, Amir Sabri, Melanie Plum, Yvonne Michel, Martin Mempel, Markus Ollert, Thilo Jakob, Simon Blank, Ingke Braren, and Edzard Spillner Allergy, 67 (12): (2012). 22 Donor substrate binding and enzymatic mechanism of human core alpha1,6- fucosyltransferase (FUT8). Miriam P. Kötzler, Simon Blank, Frank I. Bantleon, Edzard Spillner, and Bernd Meyer Biochim Biophys Acta, 1820 (12): (2012). 21 Avian IgY antibodies and their recombinant equivalents in research, diagnostics and therapy. Edzard Spillner, Ingke Braren, Kerstin Greunke, Henning Seismann, Simon Blank, Dion du Plessis Biologicals, 40 (5): (2012). 2
3 20 The putative serine protease inhibitor allergen Api m 6 from A. mellifera venom: recombinant and structural evaluation. Yvonne Michel, Mareike McIntyre, Helene Ginglinger, Markus Ollert, Liliana Cifuentes, Simon Blank, and Edzard Spillner J Investig Allergol Clin Immunol, 22 (7): (2012). 19 Perspectives, pitfalls and current status of molecular diagnosis in insect venom allergy. Edzard Spillner, Simon Blank, and Thilo Jakob Allergo Journal, 21 (4): (2012). 18 Recombinant IgE antibody engineering to target EGFR. Edzard Spillner, Melanie Plum, Simon Blank, Michaela Miehe, Josef Singer, and Ingke Braren Cancer Immunology and Immunotherapy, 61 (9): (2012). 17 Comparable IgE reactivity to natural and recombinant Api m 1 in cross-reactive carbohydrate determinant-negative patients with bee venom allergy. Thilo Jakob, Julian Köhler, Simon Blank, Ulrika Magnusson, Johannes Huss-Marp, Edzard Spillner, and Jonas Lidholm Journal of Allergy and Clinical Immunology, 130 (7): (2012). 16 The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components of Apis mellifera venom with allergenic potential beyond carbohydrate based reactivity. Simon Blank, Frank I. Bantleon, Mareike McIntyre, Markus Ollert, and Edzard Spillner Clinical and Experimental Allergy, 42 (6): (2012) Close-up of the alpha-gal epitope as defined by a monoclonal chimeric IgE and human sera using saturation transfer difference. Melanie Plum, Yvonne Michel, Kathatrina Wallach, Tim Raiber, Simon Blank, Frank Bantleon, Andrea Diethers, Kerstin Greunke, Ingke Braren and Thomas Hackl, Bernd Meyer, and Edzard Spillner Journal of Biological Chemistry, 286 (50): (2011). 14 Formation of the immunogenic α1,3-fucose epitope: Elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A. Miriam P. Kötzler, Simon Blank, Henning N. Behnken, Dirk Alpers, Frank I. Bantleon, Edzard Spillner, and Bernd Meyer Insect Biochemistry and Molecular Biology, 42 (2): (2011). 13 Rekombinante Insektengiftallergene: Ist das Bienen- oder doch das Wespengift schuld? 3
4 Thilo Jakob, Simon Blank, Edzard Spillner, and Markus Ollert Der Deutsche Dermatologe, 59: (2011). 12 Stress-resistant neural stem cells positively influence regional energy metabolism after spinal cord injury in mice. Karsten Schwerdtfeger, Angelika E.M. Mautes, Christian Bernreuther, Yifang Cui, Jérôme Manville, Marcel Dihné, Simon Blank, and Melitta Schachner Journal of Molecular Neuroscience, 46 (2): (2011). 11 Api m 10, a genuine A. mellifera venom allergen, is clinically relevant but underrepresented in therapeutic extracts. Simon Blank, Henning Seismann, Yvonne Michel, Mareike McIntyre, Ingke Braren, Thomas Grunwald, Ulf Darsow, Johannes Ring, Reinhard Bredehorst Markus Ollert, and Edzard Spillner Allergy, 66 (10): (2011). 10 Generation and epitope analysis of human monoclonal antibody isotypes with specificity for the timothy grass major allergen Phl p 5a. Julia Hecker, Andrea Diethers, Stefanie Etzold, Henning Seismann, Yvonne Michel, Melanie Plum, Reinhard Bredehorst, Simon Blank, Ingke Braren*, and Edzard Spillner* Molecular Immunology, 48 (9-10): (2011). 9 Evaluation of different glycoforms of honeybee venom major allergen phospholipase A2 (Api m 1) produced in insect cells. Simon Blank, Yvonne Michel, Henning Seismann, Melanie Plum, Kerstin Greunke Thomas Grunwald, Reinhard Bredehorst, Markus Ollert, Ingke Braren, and Edzard Spillner Protein and Peptide Letters, 18 (4): (2011). 8 Detection of IgE to a panel of species specific allergens further improves discrimination of bee and wasp venom allergy (Reply). Silke Hofmann, Nikolai Pfender, Steffi Weckesser, Simon Blank, Johannes Huss-Marp, Edzard Spillner, and Thilo Jakob Journal of Allergy and Clinical Immunology, 128 (1): 248 (2011). 7 Detection of IgE to recombinant Api m 1 and rves v 5 is valuable but not sufficient to distinguish bee from wasp venom allergy. Gunter J. Sturm, Wolfgang Hemmer, Thomas Hawranek, Roland Lang, Markus Ollert, Edzard Spillner Simon Blank, Danijela Bokanovic, and Werner Aberer Journal of Allergy and Clinical Immunology, 128 (1): (2011) Recombinant phospholipase A1 (Ves v 1) from yellow jacket venom for improved diagnosis of hymenoptera venom hypersensitivity. Henning Seismann, Simon Blank, Liliana Cifuentes, Ingke Braren, Reinhard Bredehorst, Thomas Grunwald, Markus Ollert, and Edzard Spillner Clinical and Molecular Allergy, 8: 7 (2010) 4
5 5 Identification, recombinant expression and characterization of the 100 kda high molecular weight hymenoptera venom allergens Api m 5 and Ves v 3. Simon Blank, Henning Seismann, Benjamin Bockisch, Ingke Braren, Liliana Cifuentes, Mareike McIntyre, Dana Rühl, Johannes Ring, Reinhard Bredehorst, Markus Ollert, Thomas Grunwald, and Edzard Spillner Journal of Immunology, 184 (9): (2010) Components and mechanisms in diagnosis and therapy of hymenoptera venom allergy. Simon Blank -/- Betreuer: Reinhard Bredehorst Dissertation, Hamburg (2009) 3 Dissecting cross-reactivity in hymenoptera venom allergy by circumvention of alpha- 1,3 core fucosylation. Henning Seismann, Simon Blank, Ingke Braren, Kerstin Greunke, Liliana Cifuentes, Thomas Grunwald, Reinhard Bredehorst, Markus Ollert, and Edzard Spillner Molecular Immunology, 47(4): (2010) Recombinant IgY for improvement of immunoglobulin-based analytical applications. Kerstin Greunke, Ingke Braren, Iris Alpers, Simon Blank, Jan Sodenkamp, Reinhard Bredehorst, and Edzard Spillner Clinical Biochemistry, 41: (2008) Generation of human monoclonal allergen-specific IgE and IgG antibodies from synthetic antibody libraries. Ingke Braren, Simon Blank, Henning Seismann, Susanne Deckers, Markus Ollert, Thomas Grunwald, and Edzard Spillner Clinical Chemistry, 53(5): (2007). 5
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