CMU Faculty Profile Yu-Chen Lee

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1 Yu-Chen Lee Dean, Acupuncture department of China Medicine University Hospital Assistant Professor, Graduate Institution of Acupuncture Sciences, China Medicine University Ph.D., China Medicine University (), 2011 Phone: (886) ext URL: 大頭照片 Acupuncture clinical study Academic Distinctions: The Best Physician China Medical University Hospital, Taichung, (5 times) (2000,2001, 2002, 2003, 2004) The Best Teaching Attending Physician China Medicine University Hospital, Taichung, (2008) Distinguished Teaching Professor, College of Chinese Medicine, CMU (2011) : Residentship, Department of acupuncture, China Medical University Hospital, Taichung, : Chief Resident, Department of, acupuncture China Medical University Hospital, Taichung, 2004-present: Attending pphysician, Department of Acupuncture, China Medical University Hospital, Taichung, 2006-present: Dean, Department of Acupuncture, China Medical University Hospital, Taichung, 2012-present: Assistant Professor, Graduate Institution of Acupuncture Sciences, China Medicine University The research themes in my department aim to randomized controlled clinical trial of Acupuncture, For example : Stroke,Carpal tunnel syndrome, Depression, Fibromyaligia, Rib fracture,sudden hearing loss, Back pain, so on.. Next step We want to know mechanism of acupuncture in Tranditional chinese medicine theory 1. Hsien-Yin Liao, Mao-Feng Sun, Jaung-Geng Lin, Shih-Liang Chang, * Yu-Chen Lee, * Electroacupuncture plus metformin lowers glucose levels and facilitates insulin sensitivity by activating MAPK in steroid-induced insulin-resistant rats Acupunct Med acupmed published Online First: 29 May Ming-Cheng Huang, Fu-Tzu Pai, Che-Chen Lin, Ching-Mao Chang,Hen-Hong Chang, Yu-Chen Lee, Mao-Feng Sun, Hung-Rong Yen Characteristics of Traditional Chinese Medicine Use in 1

2 Patients with Rheumatoid Arthritis in : A Nationwide Population-Based Study Journal of Ethnopharmacology Chang CC, Yu-Chen Lee #, Lin CC, Chang CH, Chiu CD, Chou LW, Sun MF, Yen HR. Characteristics of Traditional Chinese Medicine Usage in Patients with Stroke in : A Nationwide Population-based Study. Journal of Ethnopharmacology Jaung-Geng Lin, Yu-Chen Lee #, Chien-Hsin Tseng, Dai-Yin Chen, Chieh-Yun Shih, Iona MacDonald, Shih-Ya Hung, Yi-Hung Chen. Electroacupuncture inhibits pruritogen-induced spinal microglial activation in mice. Brain Research Chin-Yi Cheng, Yu Chen Lee *. Anti-inflammatory Effects of Traditional Chinese Medicines against Ischemic Injury in In Vivo Models of Cerebral Ischemia. Evidence-Based Complementary and Alternative Medicine

3 LI-WEI CHOU Director of International Master Program in Acupuncture Director of Center for International Integrative Medicine Associate Professor, Graduate Institution of Acupuncture Sciences Phone: (886) ext Acupuncture Science and Clinical research, Myofascial Pain, Rehabilitation , MD, School of Chinese Medicine, China Medical University , MSc, Institute of Medical Science, College of Medicine, CMU , PhD, Graduate Institute of Chinese Medical Science, College of Chinese Medicine, CMU , Residency training (Rehabilitation Dept.) at China Medical University Hospital (CMUH) 2002, Passed the National Board examination of Physical Medicine and Rehabilitation Since 2002, Attending Physician at the Dept of Physical Medicine and Rehabilitation in CMUH Since 2007, Chairman of Dept of Medicine, East District Branch and Fongyuan Branch, CMUH , Director of Graduate Institute of Acupuncture Science Since 2016, Director of International Master Program in Acupuncture, CMU Since 2016, Director of Center for International Integrative Medicine, CMU (1) Physical Medicine and Rehabilitation (2) Myofascial pain syndrome - trigger points injection and acupuncture (3) Acupuncture for musculoskeletal pain and post-stroke syndrome (4) Electrodiagnosis and Ultrasonography (5) Applications of neurophysiology in central nervous system and peripheral neuromuscular diseases (1) Yueh-Ling Hsieh, Li-Wei Chou, Shao-Fu Hong, Szu-Wen Tseng, Chi-Chou Huang, Ching-Hsiang Yang, Chen-Chia Yang, Wei-Feng Chiu*: Laser acupuncture attenuates oxaliplatin-induced peripheral neuropathy in patients with gastrointestinal cancer: a pilot prospective cohort study. Acupuncture in Medicine, 2016:34(5): (2) Yueh-Ling Hsieh, Chang-Zern Hong, Szu-Yu Liu, Li-Wei Chou*, Chen-Chia Yang: Acupuncture at distant myofascial trigger spots enhances endogenous opioids in rabbits: a possible mechanism for managing myofascial pain. Acupuncture in Medicine, 2016:34(4): (3) Yueh-Ling Hsieh, Chen-Chia Yang, Szu-Yu Liu, Li-Wei Chou*, Chang-Zern Hong: Remote Dose-dependent Effects of Dry needling at Distant Myofascial Trigger Spots of Rabbit Skeletal Muscles on Reduction of Substance P Levels of Proximal Muscle and Spinal Cords. BioMed Research International. Volume 2014, Article ID (4) Li-Wei Chou, Yueh-Ling Hsieh, Ta-Shen Kuan, Chang-Zern Hong: Needling therapy for myofascial pain: recommended technique with multiple rapid needle insertion. BioMedicine. 2014:4(2): (5) Bi-Huei Wang, Chien-Lin Lin, Te-Mao Li, Shih-Din Lin, Jaung-Geng Lin, Li-Wei Chou*: Selection of Acupoints for Managing Upper-extremity Spasticity in Chronic Stroke Patients.Clinical Interventions in Aging.2014:9: (6) Li-Wei Chou, Mu-Jung Kao, Jaung-Geng Lin*: Probable Mechanisms of Needling Therapies for Myofascial Pain Control. Evidence-Based Complementary and Alternative Medicine, vol. 2012, vol. 2012, Article ID (7) Yueh-Ling Hsieh, Shun-An Yang, Chen-Chia Yang, Li-Wei Chou*: Dry Needling at Myofascial Trigger Spots of Rabbit Skeletal Muscles Modulates the Biochemicals Associated With Pain, Inflammation and Hypoxia. Evidence- Based Complementary and Alternative Medicine. 2012, vol. 2012, Article ID (8) Kuo-Wei Yu, Chien-Lin Lin, Chun-Chuang Hung, Eric Chieh-Lung Chou, Yueh-Ling Hsieh, Te-Mao Li, Li-Wei Chou*: Effects of Electroacupuncture on Recent Stroke Inpatients with Incomplete Bladder Emptying: A Preliminary Study. Clinical Interventions in Aging. 2012:7: (9) Li-Wei Chou, Yueh-Ling Hsieh, Hsin-Shui Chen, Chang-Zern Hong, Mu-Jung Kao*, Ting-I Han: Remote Therapeutic Effectiveness of Acupuncture in Treating Myofascial Trigger Point of the Upper Trapezius Muscle. Am J Phys Med Rehab. 2011;90: (10) Yueh-Ling Hsieh, Li-Wei Chou, Yie-San Joe, Chang-Zern Hong*: Spinal Cord Mechanism Involving the Remote Effects of Dry Needling on the Irritability of Myofascial Trigger Spots in Rabbit Skeletal Muscle. Arch Phys Med Rehabil. 2011;92: (11) Li-Wei Chou, Yueh-Ling Hsieh, Mu-Jung Kao, Chang-Zern Hong: Remote Influences of Acupuncture on the Pain Intensity and the Amplitude Changes of Endplate Noise in the Myofascial Trigger Point of the Upper Trapezius Muscle. Arch Phys Med Rehabil 2009;90:

4 SHENG-FENG HSU Associate Professor, Graduate Institute of Acupuncture Science, College of Traditional Chinese Medicine, China Medical University, Taichung, MD Ph.D., China Medical University (), Phone: (886) ext3609 URL: Acupuncture science, Time Acupuncture, Low Level Laser Therapy (LLLT), Academic Distinctions: Distinguished Teaching Professor, College of College of Traditional Chinese Medicine, CMU (2013) : Dean, Acupuncture Research Center, China Medical University (CMU), Taichung, : Secretary General, Chinese Medical Association of Acupuncture, : Visiting Doctor, Acupuncture Department, China Medical University Hospital (CMUH), Taichung, : Deputy Director General of Chinese Medicine Department of China Medical University Hospital (CMUH), Taipei Branch : Director, Institute of Acupuncture Science, China Medical University (CMU), : Associate Professor, Institute of Acupuncture Science, China Medical University (CMU), The research themes in my study aim to understand the mechanism of electric acupuncture effect in pain control, Low Level Laser Therapy used in TMJ pain control (people), post-operation pain and strengthen body constitution (animal model). 1. A comparison of the delayed outward potassium current between the nucleus ambiguus and hippocampus:sensitivity to paeonol. Chin-TsangYang, Yuk-Man Leung, Sheng-Feng Hsu, Iona MacDonald, Mei- Ling Wang, Jaung-Geng Lin, Shih-Ya Hung*, Yi-Hung Chen*. EUROPEAN JOURNAL OF PHARMACOLOGY,2016 May,784: Chinese Herbal Products for Ischemic Stroke. I-Ling Hung, u-chiang Hung, Lin-Yi Wang, Sheng-Feng Hsu, Chen, Hsuan-Ju, Ying-Jung Tseng, Chun-En Kuo, Wen-Long Hu*, Tsai-Chung Li*. AMERICAN JOURNAL OF CHINESE MEDICINE,2015 Oct,43(7):

5 3. Spinal p38 Activity and Analgesic Effect after Low- and High-intensity Electroacupuncture Stimulation in a Plantar Incision Rat Model. Sheng-Feng Hsu, Yen-Jing Zeng, Shih-Ying Tsai, Kuen-Bao Chen, Julia Yi-Ru Chen, Ju-Hsin Chang, Yeong-Ray Wen*, LIFE SCIENCES,2015 Jan,128: Comparison of Electroacupuncture and Morphine-Mediated Analgesic Patterns in a Plantar Incision-Induced Pain Model,Evidence-based Complementary and Alternative Medicine. Yen-Jing Zeng, Shih-Ying Tsai, Kuen-Bao Chen, Sheng-Feng Hsu*, Julia Yi-Ru Chen, Yeong-Ray Wen* Nov,doi: /2014/ Laser Acupuncture Therapy in Patients with Treatment-Resistant Temporomandibular Disorder. Wen-Long Hu, Chih-Hao Chang, Yu-Chiang Hung, Ying-Jung Tseng, I-Ling Hung, Sheng-Feng Hsu. PLoS One,2014 Oct, 9(10): e DPP-4 inhibitor attenuates toxic effects of indoxyl sulfate on kidney tubular cells. Wei-Jie Wang, Chen-Hung Chang, SUN, MAO-FENG Sheng-Feng Hsu*, Ching-Sung Weng*. PLoS One,2014 Apr,9(4):e e The variations of brain activities of acupuncture to TE5 of left hand in normal subject. AMERICAN JOURNAL OF CHINESE MEDICINE. Sheng-Feng Hsu, Chien-Yue Chen*, Ming-Da Ke, Chien-Hsun Huang, Yuan-Ting Sun, Jaung-Geng Lin Oct,39(4): Electroacupuncture Analgesia, Stress Responses, and Variations in Sensitivity in Rats Anesthetized with Different Sub-MAC Anesthetics. Hsiang-Hsun Kung Sheng-Feng Hsu Yu-Chun Hung Kuen-Bao Chen Jui-Yuan Chen Yeong-Ray Wen * Wei-Zen Sun.EUROPEAN JOURNAL OF PAIN,2010 Dec,15(6):

6 YI-HUNG CHEN Professor, Grad Graduate Institute of Acupuncture Science, CMU Ph.D., National University (), 1998 Phone: (886) ext URL: acupuncture, neuropharmacology, neuroscience, itching, neuroprotection Academic Distinctions: Distinguished Teaching Professor, College of Medicine, CMU (2013) : Reviewer: Division of Pharmacology and Toxicology, Center for Drug Evaluation of : Assistant Professor: School of Nursing, Yuanpei University : Associate Professor: Graduate Institute of Acupuncture Science, CMU 2009&2012: Visiting Scholar: Department of Pharmacology, Temple University School of Medicine 2013-present: Professor: Graduate Institute of Acupuncture Science, CMU 2013-present: Professor: Master Program for Traditional Chinese Veterinary Medicine, CMU : Deputy Dean: College of Chinese Medicine, CMU 2017-present: Secretary-in-General: Neuroscience Society We focus on the studies regarding mechanisms of acupuncture on pain, itch and drug addiction and neuroprotection Lin JG, Lee YC, Tseng CH, Chen DY, Shih CY, MacDonald I, Hung SY, Chen YH* (2016) Electroacupuncture inhibits pruritogen-induced spinal microglial activation in mice. Brain Research, Lin CH, Yang CT, Tsai MC, Wu YT, MacDonald I, Wang ML, Wu CH, Keung YM* and Chen YH* (2015)(±) 3,4- Methylenedioxyamphetamine inhibits the TEA-sensitive K + current in the hippocampal neuron and the Kv2.1 current expressed in H1355 cells, Neuropharmacology, 89: Tsai KS, Chen YH, Chen HY, Shen EY, Lee YC, Shen JL, Wu SY, Lin JG, Chen YH* and Chen WC* (2014) Antipruritic Effect of Cold Stimulation at the Quchi Acupoint (LI11) in Mice, BMC Complementary and Alternative Medicine, 14:341. Chan YY, Lo WY, Li TC, Shen LJ, Yang SN, Chen YH* and Lin JG* (2014) Clinical Efficacy of Acupuncture as an Adjunct to Methadone Treatment Services for Heroin Addicts: A Randomized Controlled Trial, The American Journal of Chinese Medicine, 42:1-18. Chen YH*, Ivanic B, Chuang CM, Lu DY and Lin JG * (2013) Electroacupuncture reduces cocaine-induced seizures and mortality in mice Evidence-Based Complementary and Alternative Medicine, 2013: