ESIM: Winter School in Riga Case report
|
|
|
- Ashlyn Hopkins
- 5 years ago
- Views:
Transcription
1 ESIM: Winter School in Riga 2015 Case report Imanta Ozola Zālīte Pauls Stradins Clinical University Hospital Latvia
2
3
4 January, y., man 2-3 weeks fatigue fluidal stool 2 times per day weight loss 20 kg Psoriasis Smoking (20 pac years) BMI 17 kg/m 2 Arterial blood pressure 100/70 mmhg Heart rate 92 x Breathing rate 18 x Abdomen soft, painless CRP 32 mg/l [0 5.0 mg/l] Hb Er MCV Leu Platlets 103 g/l [ g/l] 2.3*10 12 /l [ *10 12 /l] 130 fl [ fl] 3.9*10 9 /l [ *10 9 /l] 250*10 9 /l [ *10 9 /l] Total protein 45 g/l [64 82 g/l] Albumin 31 g/l [35 50 g/l] Hidden blood in the stool - negative
5 January, 2006 Upper endoscopy Infiltrative gastric mucosa. Duodenum mucosa with scalloped, inflammated appearance. H. pylori test - negative Biopsies: Upper endoscopy Chronic active inflammation in the gastric mucosa, with incomplete erosive defects, sclerotic changes and mucosal atrophy. Massive clusters of eosinophils in the gastric mucosa. Colonoscopy Erosions in the terminal part of ileum, with fibrin and contact sangvination. Colonoscopy Crypt distortion, mikroabscesses, ulceration with diffuse lymphocyte, neutrophil infiltration. Crohn's disease. Abdominal CT Splenomegaly 15 x 4,7 cm. Mesenterial lymphadenopathy 1,2-1,8 cm.
6 January, 2007 BMI 21,4 kg/m 2 Abdominal CT, US still splenomegaly (16,7 x 5,6 cm), mesenterial lymphadenopathy February, 2008 Upper endoscopy In the gastric mucosa - 1mm large separated shallow defects with fibrin in the center. Inflammatory picture. Histology: Chronic, diffuse, active gastritis. Duodenal villous: crypt ratio 3: 1, intraepithelial lymphocytes lymphocytes per 100 epithelial cells. Morphological picture might meet celiac disease, Marsh I stage. Anti-gliadine antibodies IgA <1.2 [<12] IgG 1 [<12] PSA 0.29 [< 4 ng/ml] CEA 1.5 [< 3.4 ng/ml] CA [< 39 U/mL ]
7 May, 2011 Colonoscopy: Throughout the length of colonic mucosa segmental damage with comprehensive small erosions. Terminal ileitis with partial ileo-caecal valve stenosis. Rtg-scopia, x-ray-graphia ventriculi et intestine: contrast arcade through the gastrointestinal tract slowed, but stenotic intestinal sections can not see. Lung CT: cylindrical bronchiectasis, lung right lower lobe pneumonia
8 September, 2012 Colonoscopy: In the middle part of Colon transversus ulcerose - scarred stricture with a residual diameter of 4 mm. Throughout the length of the colon superficial, minor erosion. Histology: Active chronic ulcers (fibrin, leukocytes, fibrotic stroma). RTG-scopia, Rtg-graphia ventriculi, intestini tenue et crassi: Local colonic stricture flexura coli sinistra area - characteristic malignoma. Distal part of ileum as Crohn`s disease. Diagnostic laparotomy: Could not see malignant stricture. Took biopsy from mesenterial lymphnode. Histology conclusion: Initials B cell lymphoproliferative infiltration (only the follicle). Marginal zone lymphoma. Onkocouncil decided that lymph node histological and radiological examinations comply with the Non-Hodgkin's lymphoma. Chemotherapy indicated. By lung and abdominal CT`s follow-up, chemotherapy with positive disease course.
9 2014 Progressive fatigue Fever, body temperature > 39 0 C Upper endoscopy Visually gastric mucosal atrophy picture. Histology: Chronic active gastritis and duodenitis Makrocytic anemia (Er 3.4 milj/l, Hb 101 g/l) Vit. B12 <83 [ pg/ml] HLA - B27 negative HIV ½, HIV 1Ag- negative Hidden blood in the stool not found Colonoscopy Ileocaecal area deformation. Colon distal some tiny, pale scars. Histology: Colonic mucosa architectonics moderately deformed. Colon mucosa crypts mostly normal structure.
10 2014 Lung CT: Multiple consolidates in the both lungs, more pronounced in left lungs lower lobe limfangoitis. Granulomatous lesions in both lungs? Repeated biopsy: Transabdominal US-guided needle biopsy of the mesenteric lymph nodes Histology: Multiple epiteloid cell granulomas, including the necroses and giant cells. Granulomatous lymphadenitis, needed more data on tuberculosis. TBC investigations negative (bronchial washing, sputum, stools, GeneXpert test in sputum, stool, bronchial washing)
![? IgA <0.062 [0.7 4 g/l] IgG 0.](/docs-images/88/115083146/images/11-0.jpg "8 [7 16 g/l] IgE 0.1 [0.1 0.")
11 ? IgA <0.062 [0.7 4 g/l] IgG 0.8 [7 16 g/l] IgE 0.1 [ mg/l]
12 Common variable immunodeficiency syndrome (CVIDS) Criteria? 1) Significantly reduced total serum concentrations of IgG 2) Low IgA and/or IgM 3) Poor or absent response to immunization 4) The absence of any other defined immunodeficiency state Clinical manifestations, epidemiology, and diagnosis of common variable immunodeficiency in adults, Ahn S. Cunningham-Rundles C, Aug 27, 2013, UptoDate
13 Manifestations? Recurrent infections Lung diseases (granulamotous - "granulomatous-lymphocytic interstitial lung disease"; obstructive or restrictive disease) Gastrointestinal disease (Inflammatory bowel-like disease, which may resemble ulcerative colitis, ulcerative proctitis, Crohn's-like disease, or microscopic colitis; Sprue-like illness with flat villi; Nodular lymphoid hyperplasia; Pernicious anemia; Bacterial overgrowth; Protein-losing enteropathy; Nonspecific malabsorption; Gastrointestinal lymphoma) Autoimmune disease (Autoimmune hemolytic anemia and immune thrombocytopenia, Rheumatoid arthritis Pernicious anemia, Autoimmune thyroiditis, Vitiligo Granulomatous infiltration Lymphadenopathy/splenomegaly Malignancies (Non-Hodgkin lymphomas, gastric cancers) Clinical manifestations, epidemiology, and diagnosis of common variable immunodeficiency in adults, Ahn S. Cunningham-Rundles C, Aug 27, 2013, UptoDate
14 What else, if not CVIDS? SECONDARY hypogammaglobulinemia => Decreased production Drugs (glucocorticoids, rituximab, anti-epileptics) Malignancy and pre-malignant disorders (chronic lymphocytic leukemia, lymphoma, multiple myeloma) Systemic illnesses causing bone marrow suppression Thymoma => Increased loss protein-losing enteropathies, such as intestinal lymphangiectasia, nephrotic syndrome, burns, traumas (loss of fluids) PRIMARY hypogammaglobulinemia (in adults) IgG subclass deficiencies Hyper IgM syndromes Combined immunodeficiency's Clinical manifestations, epidemiology, and diagnosis of common variable immunodeficiency in adults, Ahn S. Cunningham-Rundles C, Aug 27, 2013, UptoDate
15 Paldies par uzmanību!
What is your diagnosis? a. Lymphocytic colitis. b. Collagenous colitis. c. Common variable immunodeficiency (CVID) associated colitis
Case History A 24 year old male presented with fatigue, fever, watery diarrhea, and a cough with sputum production for the past three weeks. His past medical history was significant for recurrent bouts
A Practical Approach to Small Bowel Biopsies: All that flattens is not sprue
A Practical Approach to Small Bowel Biopsies: All that flattens is not sprue UCSF Liver and Gastrointestinal Pathology Update Sept. 4, 2009 How to Go Wrong When Evaluating Small Bowel Biopsies, Based on
PATHOLOGY OF NON NEOPLASTIC LESIONS OF THE UPPER GASTROINTESTINAL TRACT.
PATHOLOGY OF NON NEOPLASTIC LESIONS OF THE UPPER GASTROINTESTINAL TRACT. OESOPHAGEAL LESIONS OESOPHAGITIS AND OTHER NON NEOPLASTIC DISORDERS Corrosive Gastroesophageal reflux (GERD), Pills, Acid intake,
COMMON VARIABLE IMMUNODEFICIENCY
COMMON VARIABLE IMMUNODEFICIENCY This booklet is intended for use by patients and their families and should not replace advice from a clinical immunologist. 1 COMMON VARIABLE IMMUNODEFICIENCY Also available
Abstracting Hematopoietic Neoplasms
CASE 1: LYMPHOMA PHYSICAL EXAMINATION 43yo male with a history of lower gastrointestinal bleeding and melena undergoing colonoscopy and biopsy to rule out neoplasm versus inflammation. Patient had no other
Gastrointestinal Disorders. Disorders of the Esophagus 3/7/2013. Congenital Abnormalities. Achalasia. Not an easy repair. Types
Gastrointestinal Disorders Congenital Abnormalities Disorders of the Esophagus Types Stenosis Atresia Fistula Newborn aspirates while feeding. Pneumonia Not an easy repair Achalasia Lack of relaxation
Baring the facts to uncover the naked truth: the stubborn puzzle
Baring the facts to uncover the naked truth: the stubborn puzzle Dr. Ieva Ruža Riga East Clinical University Hospital Dr. Inta Leitāne Riga Health Centre, Tornakalna Outpatient Clinic, Latvia ESIM Clinico-pathological
Osteosclerotic Myeloma (POEMS Syndrome)
Osteosclerotic Myeloma (POEMS Syndrome) Osteosclerotic Myeloma (POEMS Syndrome) Synonyms Crow-Fukase syndrome Multicentric Castleman disease Takatsuki syndrome Acronym coined by Bardwick POEMS Scheinker,
Case Discussion. Nutrition in IBD. Rémy Meier MD. Ulcerative colitis. Crohn s disease
26.08.2017 Case Discussion Nutrition in IBD Crohn s disease Ulcerative colitis Rémy Meier MD Case Presentation 30 years old female, with diarrhea for 3 months Shool frequency 3-4 loose stools/day with
Coeliac Disease: Diagnosis and clinical features
Coeliac Disease: Diagnosis and clinical features Australasian Gastrointestinal Pathology Society AGM 28 Oct 2016 Dr. Hooi Ee Gastroenterologist, Sir Charles Gairdner Hospital Coeliac disease Greek: koiliakos
Lymphatic System Disorders
Lymphatic System Disorders Lymphomas Malignant neoplasms involving lymphocyte proliferation in lymph nodes Specific causes not identified // Higher risk in adults who received radiation during childhood
Diffuse Nodular Lymphoid Hyperplasia of the Intestine Caused by Common Variable Immunodeficiency and Refractory Giardiasis
CASE REPORT Diffuse Nodular Lymphoid Hyperplasia of the Intestine Caused by Common Variable Immunodeficiency and Refractory Giardiasis Jung Hye Choi 1,DongSooHan 1, Jieun Kim 1, Kijong Yi 2, Young-Ha Oh
Mohamed EL-hemaly Gastro- intestinal surgical center, Mansoura University.
Mohamed EL-hemaly Gastro- intestinal surgical center, Mansoura University. Chronic transmural inflammatory process of the bowel & affects any part of the gastro -intestinal tract from the mouth to the
Kids Like to Break the Rules: Gastrointestinal Pathology in Children
Kids Like to Break the Rules: Gastrointestinal Pathology in Children Jeffrey Goldsmith MD Director of Surgical Pathology, Beth Israel Deaconess Medical Center; Consultant in Gastrointestinal Pathology,
Coeliac Disease Bible Class Questions and Answers
Coeliac Disease Bible Class Questions and Answers Jan Hendrik Niess What is the definition of coeliac disease? Coeliac disease is an immune reaction to gluten (wheat, barely, rye) in an genetic predisposed
Kristin Kenrick, FRNZCGP Department of General Practice and Rural Health Dunedin School of Medicine (Supported by Coeliac New Zealand)
Kristin Kenrick, FRNZCGP Department of General Practice and Rural Health Dunedin School of Medicine (Supported by Coeliac New Zealand) That you will go away thinking about your practice population, and
Case conference. Welcome Dr. Lawrence Tierney
Case conference Welcome Dr. Lawrence Tierney Case: 18 year-old male CC) hamatomesis, Fever and cough HPI) 1 st admission One month ago, he admitted to our hospital because of hematemesis. He had weight
Refractory celiac disease (RCD) KASSEM BARADA LEBANESE SOCIETY OF GASTROENTEROLOGY NOVEMBER, 2014
Refractory celiac disease (RCD) KASSEM BARADA LEBANESE SOCIETY OF GASTROENTEROLOGY NOVEMBER, 2014 Case scenario (1) A 49 year woman presents with intermittent watery diarrhea and bloating of two years
Sheila E. Crowe, MD, FRCPC, FACP, FACG, AGAF Department of Medicine University of California, San Diego
Severe and Emergency Presentations of Celiac Disease Sheila E. Crowe, MD, FRCPC, FACP, FACG, AGAF Department of Medicine University of California, San Diego Case Presentation (1) 63 year old male transferred
IBD. Crohn s. Outline. Ulcerative colitis versus Crohn s disease: is biopsy useful? UC vs. Crohn s? Is it easy? Biopsy settings 21/07/2017 IBD
Outline Ulcerative colitis versus Crohn s disease: is biopsy useful? Roger Feakins Colorectal biopsies Ileal and upper GI biopsies Special situations New techniques Summary Inflammatory bowel disease (IBD)
Celiac Disease. M. Nedim Ince, MD University of Iowa Hospital
Celiac Disease M. Nedim Ince, MD University of Iowa Hospital Contents Cases Definition Etiopathogenesis Pathology Diagnosis Management of the disease Management of complications Case I Five year old boy
HDF Case Whipple s disease
HDF Case 952556 Whipple s disease 63 yo female complaining of a diarrhea for 2 months, weigth loss (12 Kg in 3 months), and joint pains. Duodenal biopsy performed. Scanning view, enlarged intestinal villi,
Helicobacter and gastritis
1 Helicobacter and gastritis Dr. Hala Al Daghistani Helicobacter pylori is a spiral-shaped gram-negative rod. H. pylori is associated with antral gastritis, duodenal (peptic) ulcer disease, gastric ulcers,
Normal small intestine Variations
THE HISTOPATHOLOGICAL DIAGNOSIS OF THE TERMINAL ILEUM BIOPSY K. Geboes, MD, PhD, AGAF, dr. H.C. Belgium Normal small intestine Variations Duodenum Ileum 1 Proliferative compartment Normal variations 2
What do we need for diagnosis of IBD
What do we need for diagnosis of IBD Kaichun Wu Dept. of Gastroenterology, Xijing Hospital Fourth Military Medical University Xi an an,, China In China UC 11.6/10 5,CD 1.4/10 5 Major cause of chronic diarrhea
Recurrent Intestinal Obstruction in a Patient with Selective IgA Deficiency
Case Report Recurrent Intestinal Obstruction in a Patient with Selective IgA Deficiency Chee-Kin Hui 1,2 Submitted: 27 May 2015 Accepted: 27 Mar 2016 Online: 7 Dec 2016 1 Centre for Alimentary Studies,
Gastric Polyps. Bible class
Gastric Polyps Bible class 29.08.2018 Starting my training in gastroenterology, some decades ago, my first chief always told me that colonoscopy may seem technically more challenging but gastroscopy has
ABDOMINAL PAIN AND DIARRHEA - IT S NOT (ALWAYS) WHAT YOU THINK. Yakov Wainer, MD Gastroenterology and Hepatology Meir Medical Center
ABDOMINAL PAIN AND DIARRHEA - IT S NOT (ALWAYS) WHAT YOU THINK Yakov Wainer, MD Gastroenterology and Hepatology Meir Medical Center 1 ST ADMISSION - 2015 38 y/o female Abdominal pain, diarrhea - intermittent
Tips for Managing Celiac Disease. Robert Berger MD FRCPC Gastroenterology New Brunswick Internal Medicine Update April 22, 2016
Tips for Managing Celiac Disease Robert Berger MD FRCPC Gastroenterology New Brunswick Internal Medicine Update April 22, 2016 Disclosures None relevant to this presentation Objectives Briefly review the
The Role of Ultrasound in the Assessment of Inflammatory Bowel Disease
The Role of Ultrasound in the Assessment of Inflammatory Bowel Disease Dr. Richard A. Beable Consultant Gastrointestinal Radiologist Queen Alexandra Hospital Portsmouth Hospitals NHS Trust Topics for Discussion
Level 2. Non Responsive Celiac Disease KEY POINTS:
Level 2 Non Responsive Celiac Disease KEY POINTS: Celiac Disease (CD) is an autoimmune condition triggered by ingestion of gluten leading to intestinal damage and a variety of clinical manifestations.
FBC interpretation. Dr. Gergely Varga
FBC interpretation Dr. Gergely Varga #1 71 Y/O female, c/o weakness Test Undertaken : FBC (FBC) Sample Type: Whole Blood [ - 26.09.11 14:59] Hb 7.3 g/dl* 12.0-15.5 RBC 3.5 10^12/l * 3.80-5.60 Hct 0.24
INVESTIGATIONS OF GASTROINTESTINAL DISEAS
INVESTIGATIONS OF GASTROINTESTINAL DISEAS Lecture 1 and 2 دز اسماعيل داود فرع الطب كلية طب الموصل Radiological tests of structure (imaging) Plain X-ray: May shows soft tissue outlines like liver, spleen,
Lower Gastrointestinal Tract KNH 406
Lower Gastrointestinal Tract KNH 406 Lower GI Tract A&P Small Intestine Anatomy Duodenum, jejunum, ileum Maximum surface area for digestion and absorption Specialized enterocytes from stem cells of crypts
USCAP Pediatric Pathology Speciality Conference Case 3. S.Ranganathan, MD Children s Hospital of Pittsburgh of UPMC 4/13/2016
USCAP Pediatric Pathology Speciality Conference - 2016 SPP asks all individuals involved in the development and presentation of Continuing Medical Education (CME) activities to disclose all relationships
FM CFS leaky gut April pag 1
FM CFS leaky gut April 21 2018 pag 1 FIBROMYALGIA / CHRONIC FATIGUE SYNDROME AND LEAKY GUT. SUMMARY OF CLINICAL TRIAL DESIGN. Double-blind randomized placebo-controlled challenge with gluten and milk protein
Lymphocytic Gastritis, Isolated Type Occurring in Family Members. A Case Report.
Lymphocytic Gastritis, Isolated Type Occurring in Family Members. A Case Report. Alan Shienbaum, DO; AndriyPavlenko, MD; Jun Liu, MD, PhD; Janusz J Godyn, MD. Pathology Department, Kennedy University Hospitals,
Oncologist-induced Disease of the GI tract: New Developments
Oncologist-induced Disease of the GI tract: New Developments Jeffrey D Goldsmith, MD Children s Hospital Boston, Beth Israel Deaconess Medical Center, Harvard Medical School Boston, MA Everyone s on drugs
CASE PRESENTATION. Kārlis Rācenis MD - Latvia
CASE PRESENTATION Kārlis Rācenis MD - Latvia o Patient men, 32-years-old o Admitted to the hospital at 12.09.16 due to kidney biopsy no complains 21.07 29.07.2016 Admitted to the hospital Acute kidney
Pathology of Hematopoietic and Lymphoid tissue
Pathology of Hematopoietic and Lymphoid tissue Peerayut Sitthichaiyakul, M.D. Department of Pathology and Forensic Medicine Faculty of Medicine, Naresuan University CONTENTS White blood cells and lymph
ד"ר דוד ירדני המכון לגסטרואנטרולוגיה ומחלות כבד מרכז רפואי סורוקה
ד"ר דוד ירדני המכון לגסטרואנטרולוגיה ומחלות כבד מרכז רפואי סורוקה Presentaion: S.A is 38 years old. Referred for rectal bleeding investigation. Describes several occasions of bleeding and abdominal pain.
Original Article. Evaluation of Small Intestinal Biopsies in Malabsorption Syndromes
Original Article Evaluation of Small Intestinal Biopsies in Malabsorption Syndromes Ashmeet Kaur 1 *, Poojaba Jadeja 2, Neha Garg 2, SML Rai 2 and N. Mogra 2 1 Department Of Pathology, Santokba Durlabhji
Pathology of Hematopoietic and Lymphoid tissue
CONTENTS Pathology of Hematopoietic and Lymphoid tissue White blood cells and lymph nodes Quantitative disorder of white blood cells Reactive lymphadenopathies Infectious lymphadenitis Tumor metastasis
PRIMARY IMMUNODEFICIENCIES CVID MANAGEMENT CVID MANAGEMENT
PRIMARY IMMUNODEFICIENCIES CVID MANAGEMENT CVID MANAGEMENT 1 PRIMARY IMMUNODEFICIENCIES KEY ABBREVIATIONS CVID CT IgA IgG IgM IPOPI IVIG SCIG PID Common Variable Immune Deficiency Computerised tomography
Is it CVID? Not Necessarily HAIG TCHEUREKDJIAN, MD
Is it CVID? Not Necessarily HAIG TCHEUREKDJIAN, MD Current Paradigm of Pathogenesis Genetic defect(s) Molecular defect(s) Cellular defect(s) Clinical disease Current Paradigm of Pathogenesis Genetic defect(s)
NCD for Fecal Occult Blood Test
NCD for Fecal Occult Blood Test Applicable CPT Code(s): 82272 Blood, occult, by peroxidase activity (e.g., guaiac), qualitative, feces, 1-3 simultaneous determinations, performed for other than colorectal
Recurrent Infection, Pulmonary Disease, and Autoimmunity as Manifestations of Immune Deficiency
Recurrent Infection, Pulmonary Disease, and Autoimmunity as Manifestations of Immune Deficiency Erwin W. Gelfand, M.D. Professor, Department of Pediatrics National Jewish Health Professor of Immunology
Biomarkers of GI tract diseases. By Dr. Gouse Mohiddin Shaik
By Dr. Gouse Mohiddin Shaik Introduction The gastrointestinal (GI) tract is a complex system performing multiple biological functions which are anatomically distributed Site for food processing and absorption
Differentiation Between Ileocecal Tuberculosis and Crohn s Disease using a Combination of Clinical, Endoscopic and Histological Characteristics
38 Original Article Differentiation Between Ileocecal Tuberculosis and Crohn s Disease using a Combination of Clinical, Endoscopic and Histological Characteristics Anuchapreeda S Leelakusolvong S Charatcharoenwitthaya
Autoimmunity and Primary Immune Deficiency
Autoimmunity and Primary Immune Deficiency Mark Ballow, MD Division of Allergy & Immunology USF Morsani School of Medicine Johns Hopkins All Children s Hospital St Petersburg, FL The Immune System What
IBD 101. Ronen Stein, MD Assistant Professor of Clinical Pediatrics Division of Gastroenterology, Hepatology, and Nutrition
IBD 101 Ronen Stein, MD Assistant Professor of Clinical Pediatrics Division of Gastroenterology, Hepatology, and Nutrition Objectives Identify factors involved in the development of inflammatory bowel
CHRONIC ULCERATIVE JEJUNITIS
GASTROENTEROLOGY Copyright " 1971 by The Williams & Wilkins Co. Vol. 60, No. 1 Printed in U. S. A. CHRONIC ULCERATIVE JEJUNITIS Report of a case and discussion of classification MORDEKHAI MORITZ, M.D.,
HYPER IgM SYNDROME This booklet is intended for use by patients and their families and should not replace advice from a clinical immunologist.
HYPER IgM SYNDROME This booklet is intended for use by patients and their families and should not replace advice from a clinical immunologist. 1 HYPER IgM SYNDROME Also available : COMMON VARIABLE IMMUNODEFICIENCY
Crohn s Disease. Resident Lecture 1/17/19
Crohn s Disease Resident Lecture 1/17/19 Objectives Features/Classification of Crohn s Disease Medical Treatment Surgical Indications Surgical Considerations 2 Case 25 yo F presents to your office with
Radiological Manifestations of Common Variable Immuodeficiency Sydrome (CVID) and associated complications
Radiological Manifestations of Common Variable Immuodeficiency Sydrome (CVID) and associated complications Poster No.: P-0034 Congress: ESTI 2014 Type: Educational Poster Authors: A. Wallis, C. Ball, K.
Common Variable ImmunoDeficiency
Common Variable ImmunoDeficiency (CVID) Nima Rezaei, MD, PhD Deputy President of Research Center for Immunodeficiencies, Children s Medical Center, Pediatrics Center of Excellence, Associate Dean of International
7 Omar Abu Reesh. Dr. Ahmad Mansour Dr. Ahmad Mansour
7 Omar Abu Reesh Dr. Ahmad Mansour Dr. Ahmad Mansour -Leukemia: neoplastic leukocytes circulating in the peripheral bloodstream. -Lymphoma: a neoplastic process in the lymph nodes, spleen or other lymphatic
Grand round on a case of ileocecal tuberculosis. Presenters Alula (R3) Getahun (R1) Berhanu (Intern) Department of internal medicine April 2014
Grand round on a case of ileocecal tuberculosis Presenters Alula (R3) Getahun (R1) Berhanu (Intern) Department of internal medicine April 2014 Introduction: Extrapulmonary tuberculosis prevalence: Seropositive:
Intestinal tuberculosis and tuberculous peritonitis
Intestinal tuberculosis and tuberculous peritonitis GAO Hong Department of Gastroenterology, Zhongshan Hospital Fudan University Objectives 1. To master the clinical manifestations, complications, diagnosis
Bleeding in the Digestive Tract
Bleeding in the Digestive Tract National Digestive Diseases Information Clearinghouse National Institute of Diabetes and Digestive and Kidney Diseases NATIONAL INSTITUTES OF HEALTH U.S. Department of Health
Small Bowel Cases. Introduction. Introduction, Continued 12/7/2011. Lesions Found on endoscopic biopsies Just Like Signing Out
Small Bowel Cases Lesions Found on endoscopic biopsies Just Like Signing Out Introduction Small intestinal biopsies have a few special pitfalls, for example: Neuroendocrine tumors are readily mistaken
155.2 Malignant neoplasm of liver not specified as primary or secondary. C22.9 Malignant neoplasm of liver, not specified as primary or secondary
ICD-9 TO ICD-10 Reference ICD-9 150.9 Malignant neoplasm of esophagus unspecified site C15.9 Malignant neoplasm of esophagus, unspecified 151.9 Malignant neoplasm of stomach unspecified site C16.9 Malignant
IBD-Related Lymphoma
IBD-Related Lymphoma Larry Burgart MD Staff Pathologist, Allina Health and Minnesota Gastroenterology Clinical Professor of Pathology, University of Minnesota College of Medicine IBD-Related Lymphoma
Update on the pathological classification of gastritis. Hala El-Zimaity, M.D. M.S. Epidemiology McMaster University Hamilton, Ontario Canada
Update on the pathological classification of gastritis Hala El-Zimaity, M.D. M.S. Epidemiology McMaster University Hamilton, Ontario Canada CLASSIFICATION GASTRITIS GASTROPATHY 1. Acute 2. Chronic 3. Uncommon
HCPCS Codes (Alphanumeric, CPT AMA) ICD-9-CM Codes Covered by Medicare Program
HCPCS s (Alphanumeric, CPT AMA) 82272 Blood, occult, by peroxidase activity (e.g., guaiac), qualitative, feces, 1-3 simultaneous determinations, performed for other than colorectal neoplasm screening ICD-9-CM
Capsule Endoscopy: Is it Really Helpful in the Diagnosis of Small Bowel Diseases? Kashif Malik, Muhammad Joher Amin, Syed Waqar Hassan Shah
Original Article Capsule Endoscopy: Is it Really Helpful in the Diagnosis of Small Bowel Diseases? Kashif Malik, Muhammad Joher Amin, Syed Waqar Hassan Shah ABSTRACT Objective: To determine the diagnostic
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE SCOPE. Coeliac disease: recognition, assessment and management of coeliac disease
Appendix B: NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE 1 Guideline title SCOPE Coeliac disease: recognition, assessment and management of coeliac disease 1.1 Short title Coeliac disease 2 The remit
Pitfalls in the Diagnosis of Inflammatory Bowel Disease
Pitfalls in the Diagnosis of Inflammatory Bowel Disease Robert H Riddell MD Mt Sinai Hospital Toronto Prof of Lab. Medicine and Pathobiology University of Toronto Atypical gross / endoscopic distribution
Autoimmunity and autoinflammation
Autoimmunity and autoinflammation Primary immunodeficiencies Autoimmunity and autoinflammation 1 Primary immunodeficiencies List of some common abbreviations APECED CAPS CGD CINCA CRMO CVID FCAS FMF HIDS
A. Incorrect! The duodenum drains to the superior mesenteric lymph nodes. B. Incorrect! The jejunum drains to the superior mesenteric lymph nodes.
USMLE Step 1 Problem Drill 11: Immunology Question No. 1 of 10 1. A 67 year old man is discovered to have metastatic disease involving his inferior mesenteric lymph nodes. His primary cancer is most likely
BIOPSY DIAGNOSIS OF COLITIS Common and Unusual Forms of Inflammatory Bowel disease
BIOPSY DIAGNOSIS OF COLITIS Common and Unusual Forms of Inflammatory Bowel disease David A Owen University of British Columbia CAUSES OF DIARRHEA DIARRHEA COLITIS PRESENT COLITIS ABSENT INFECTIOUS NON-INFECTIOUS
Case History B Female patient 1970 Clinical History : crampy abdominal pain and episodes of bloody diarrhea Surgical treatment
Case History B-1325945 Female patient 1970 Clinical History : crampy abdominal pain and episodes of bloody diarrhea Surgical treatment Case History B-1325945 Pathology Submucosa & Muscularis Endometriosis
ACG Clinical Guideline: Diagnosis and Management of Celiac Disease
ACG Clinical Guideline: Diagnosis and Management of Celiac Disease Alberto Rubio-Tapia, MD 1, Ivor D. Hill, MD 2, Ciarán P. Kelly, MD 3, Audrey H. Calderwood, MD 4 and Joseph A. Murray, MD 1 1 Division
Grand Rounds: A 42-Year-Old Man with Chest, Abdominal Discomfort. By Ari Thomas, Danielle Levine and Laurel Edington
Grand Rounds: A 42-Year-Old Man with Chest, Abdominal Discomfort By Ari Thomas, Danielle Levine and Laurel Edington Case Presentation 42-year old male Chief complaint chest and abdominal discomfort for
A heterogeneous collection of diseases characterised by hypogammaglobulinemia.
1 Common variable immunodeficiency () A heterogeneous collection of diseases characterised by hypogammaglobulinemia. Although is the most common primary immune deficiency (PID) symptomatic in adults, it
Laboratory Methods for Diagnosing Celiac Disease. Vijay Kumar, PhD, FACB IMMCO Diagnostics, Inc. Buffalo, NY
Laboratory Methods for Diagnosing Celiac Disease Vijay Kumar, PhD, FACB IMMCO Diagnostics, Inc. Buffalo, NY Prevalence of Celiac Disease Group With Symptoms Adults Children Associated Symptoms Chronic
Guided by Dr. Michal Amitai Head of Abdominal Imaging Department of Diagnostic Imaging Sheba Medical Center Sackler School of Medicine, Tel Aviv
Guided by Dr. Michal Amitai Head of Abdominal Imaging Department of Diagnostic Imaging Sheba Medical Center Sackler School of Medicine, Tel Aviv University 1 SHARE study My year Collaboration between gastroenterology
Clinical Radiological Pathological Conference
Clinical Radiological Pathological Conference CASE 1: A 59-year-old female Housekeeper Live in Phuket, Thailand Progressive dyspnea for 1 year Present illness 1 year PTA : She developed dyspnea on exertion
Surgical Management of IBD. Val Jefford Grand Rounds October 14, 2003
Surgical Management of IBD Val Jefford Grand Rounds October 14, 2003 Introduction Important Features Clinical Presentation Evaluation Medical Treatment Surgical Treatment Cases Overview Introduction Two
Chapter 11. Hyper IgM Syndromes
Chapter 11 Hyper IgM Syndromes Patients with Hyper-IgM (HIGM) syndrome are susceptible to recurrent and severe infections and in some types of HIGM syndrome opportunistic infections and an increased risk
Hematology 101. Rachid Baz, M.D. 5/16/2014
Hematology 101 Rachid Baz, M.D. 5/16/2014 Florida 101 Epidemiology Estimated prevalence 8,000 individuals in U.S (compare with 80,000 MM patients) Annual age adjusted incidence 3-8/million-year 1 More
objectives Pitfalls and Pearls in PET/CT imaging Kevin Robinson, DO Assistant Professor Department of Radiology Michigan State University
objectives Pitfalls and Pearls in PET/CT imaging Kevin Robinson, DO Assistant Professor Department of Radiology Michigan State University To determine the regions of physiologic activity To understand
Case Report Seronegative Intestinal Villous Atrophy: A Diagnostic Challenge
Case Reports in Gastrointestinal Medicine Volume 2016, Article ID 6392028, 4 pages http://dx.doi.org/10.1155/2016/6392028 Case Report Seronegative Intestinal Villous Atrophy: A Diagnostic Challenge Cláudio
Crohn's disease of the duodenum
Crohn's disease of the duodenum F. WARREN NUGENT,' M. RICHMOND,2 AND S. K. PARK3 Gut, 1977, 18, 115-120 From the Department of Gastroenterology, Lahey Clinic Foundation, Boston, Massachusetts, USA SUMMARY
Histologic Follow-up of People With Celiac Disease on a Gluten-Free Diet Slow and Incomplete Recovery
Anatomic Pathology / HISTOLOGIC FOLLOW-UP OF PEOPLE WITH CELIAC DISEASE ON A GLUTEN-FREE DIET Histologic Follow-up of People With Celiac Disease on a Gluten-Free Diet Slow and Incomplete Recovery Peter
Birthday: 1952/07/31 Date of admission:1999/12/30 Age:48 y/o Past medication:esrd under regular HD for 5+ years; denied DM and HTN
Birthday: 1952/07/31 Date of admission:1999/12/30 Age:48 y/o Past medication:esrd under regular HD for 5+ years; denied DM and HTN Chief Complaint : 1)intermittent LLQ cramping pain for 2 months 2) LGI
Primary Immunodeficiency
Primary Immunodeficiency DiGeorge Syndrome Severe Combined Immunodeficiency SCID X-Linked Agammaglobulinemia Common variable immunodeficiency (CVID) IgA deficiency Hyper- IgM Syndrome Wiskott-Aldrich syndrome
SUMMARY Coeliac disease is a common food intolerance in Western populations, in which it has a prevalence of about 1%. In early infancy, when the transition is made to a gluten-containing diet (particularly
Malabsorption: etiology, pathogenesis and evaluation
Malabsorption: etiology, pathogenesis and evaluation Peter HR Green NORMAL ABSORPTION Coordination of gastric, small intestinal, pancreatic and biliary function Multiple mechanisms Fat protein carbohydrate
manifestations are uncommon. Initial descriptions of the disease (Rosai and Dorfman, 1969) specifically
Postgraduate Medical Journal (July 1980) 56, 521-525 Diffuse cutaneous involvement and sinus histiocytosis with massive lymphadenopathy A. A. WOODCOCK B.Sc., M.B., Ch.B., M.R.C.P. Summary Severe skin involvement
Coeliac disease with histological features of peptic duodenitis: Value of assessment of intraepithelial lymphocytes
420 4 Clin Pathol 1993;46:420-424 Department of Pathology, St James's Hospital and Trinity College, Dublin Ireland M D Jeffers D O'B Hourihane Correspondence to: Professor D O'B Hourihane Accepted for
The focus of this week s lab will be pathology of the gastrointestinal and hepatobiliary systems.
GASTROINTESTINAL AND HEPATOBILIARY SYSTEMS The focus of this week s lab will be pathology of the gastrointestinal and hepatobiliary systems. GASTROINTESTINAL SYSTEM AND HEPATOBILIARY SYSTEM We will examine
Lymphoma: What You Need to Know. Richard van der Jagt MD, FRCPC
Lymphoma: What You Need to Know Richard van der Jagt MD, FRCPC Overview Concepts, classification, biology Epidemiology Clinical presentation Diagnosis Staging Three important types of lymphoma Conceptualizing
Plan. Sarcoidosis 21/07/2017. Sarcoidosis Liver involvement. Sarcoidosis GI involvement. Sarcoidosis Diagnosis
Belfast Pathology 2017 Gastrointestinal tract involvement by systemic disease 21.6.17 Dr Adrian C. Bateman University Hospital Southampton NHS Foundation Trust, UK Plan Dermatological conditions Chronic
IBD 101. Ronen Stein, MD Assistant Professor of Clinical Pediatrics Division of Gastroenterology, Hepatology, and Nutrition
IBD 101 Ronen Stein, MD Assistant Professor of Clinical Pediatrics Division of Gastroenterology, Hepatology, and Nutrition Objectives Identify factors involved in the development of inflammatory bowel
Methotrexate-associated Lymphoproliferative Disorders
Methotrexate-associated Lymphoproliferative Disorders Definition A lymphoid proliferation or lymphoma in a patient immunosuppressed with methotrexate, typically for treatment of autoimmune disease (rheumatoid
Unexpected Findings at Endoscopy
The Endoscopic Incidentaloma: What to Tell Your Patient t with Unexpected Endoscopic Findings: Gastric Intestinal Metaplasia, Silent Ileitis, Carcinoid David Greenwald, MD Montefiore Medical Center Albert
Inflammatory Bowel Disease When is diarrhea not just diarrhea?
Inflammatory Bowel Disease When is diarrhea not just diarrhea? Jackie Kazik, MA, PA C CME Resources CAPA Annual Conference, 2011 Inflammatory Bowel Disease Objectives Discuss what is known about the pathophysiology
Pediatric Oncology. Vlad Radulescu, MD
Pediatric Oncology Vlad Radulescu, MD Objectives Review the epidemiology of childhood cancer Discuss the presenting signs and symptoms, general treatment principles and overall prognosis of the most common
2015 복영증례 51/M C.C. Past Hx: DM, HTN (1998), Lab: WBC (11500/ μl ), CRP (0.71 mg/dl) 순천향서울병원황지영, 홍성숙 APCT (HAD #1) APCT (HAD#1) APCT (HAD #15)
Case 1 2015 복영증례 순천향서울병원황지영, 홍성숙 51/M C.C Abdominal pain and chilling (1 week ago) Diarrhea (a month ago) Past Hx: DM, HTN (1998), Alcoholic liver disease (2008) Lab: WBC (11500/ μl ), CRP (0.71 mg/dl)