Rama Nada. - Mousa Al-Abbadi. 1 P a g e
|
|
- Marybeth Russell
- 5 years ago
- Views:
Transcription
1 - 1 - Rama Nada - - Mousa Al-Abbadi 1 P a g e
2 Bones, Joints and Soft tissue tumors Before we start: the first 8 minutes was recalling to Dr.Mousa s duties, go over them in the slides. Wherever you see * refer to the page index at the bottom of the page (things that are written by red in the index are not mentioned by the doctor but may help you in understanding) These are the objects that well discuss in the coming 8 lectures: 1-Remember the basic structure & function of bone 2-Congenital diseases of bone and cartilage 3-Metabolic disorders of bone 4-Paget disease of bone* 5-Fractures 6-Osteonecrosis 7-Osteomyelitis** 8-Bone tumors and tumor-like conditions 9-Arthritis**: (very common diseases) Osteoarthritis; RA; Juvenile Idiop A Seronegative Spondyloarthropathies Infectious arthritis; Lyme arthritis Crystal-induced arthritis (such as: gout and pseudogout***) 10-Joint tumors & tumorlike conditions (not common conditions) 11- Soft tissue tumors: Adipose tissue; fibrous tissue; skeletal muscle Smooth muscle; tumors of uncertain origin Relax you don t need to understand or to memorize them here, you ll do that over lectures. *It is a localized disorder of bone remodeling **inflammation conditions ***It s important to differentiate between them later (there is a question about them in the exam) 2 P a g e
3 Important note pathologists should not make diagnoses for bone diseases or tumors based on pathological features only, instead they should first corelate these pathological features with clinical data. For example: woven bones in adult femur indicate a pathological condition, you may think that is an osteogenic sarcoma but when you know from the patient history that he/she has a fracture recently you ll know that they are present normally as a part of repair. Bone functions: 1-Provide a Mechanical support; a problem in a patient s bone impair his/her mechanical support. 2-Forces transmission; forces and weights are balanced by bones, from the skull on the shoulders and upper limbs then the thoraces, the pelvic and the lower limbs. For example: impairment in the hip bone imbalance the patient s walk. 3-Protection; your skull protects your brain from hits 4- Mineral homeostasis*; control your calcium phosphorus metabolism. Problems in the factors that are related to mineral homeostasis, such as: parathyroid hormones (hyperparathyroidism) and vitamin D (vitamin D deficiency/ rickets), can cause many problems in bones. 5- Haematopoiesis; most of your blood elements** are synthesized from stem cells in the bone marrow especially in the long bones, so problems in the bones affect blood elements. *bones act as reservoir for minerals that are important to our body such as calcium and phosphate. A certain concentration of calcium or other minerals inside the blood should be maintained, so when the body needs calcium, calcium will be mobilized from the bone to increase calcium blood level. On the other hand, if you increase your intake of calcium, more deposition of calcium inside the bone occurs. **Red blood cells, white blood cells and platelets 3 P a g e
4 Bone structure: Bone structure Matrix Cells Osteoid 35%: organic type I collagen and glycosaminoglycans & other proteins Minerals 65%: One of them is Inorganic hydroxyapatite which make your bones hard, decrease in it results in soft bones (pathological condition) Osteoblasts: forms bone and forms the osteoid The balance between osteoblasts and osteoclasts: Osteoclasts: Specialized multinucleated macrophages, derived from circulating monocytes, responsible for bone resorption Osteocytes: mature bone cells (mature osteoblasts), these cells have many processes (dendrites like structures) In the childhood the activity of osteoblasts are higher than it for osteoclasts (bone formation more than bone resorption), they reach the peak of their activity in the early adulthood, from that period up to the 4 th decade they activity of osteoblasts still higher than it for osteoclasts but not as much as before, at the 4 th decade of age the activity for both types of cells are in homeostasis (nearly equal), but after that the activity for osteoblasts decrease while it increases for osteoclasts, so bones resorption more than bones formation, that leads to what we call osteoporosis especially in women post-menopausal. How to prevent or delay osteoporosis? You can decrease osteoporosis by controlling your lifestyle (increase your activity) and food (get species with large amount of minerals), more exposure to sun light (vitamin D) and there are some drugs that can help. A beneficial picture from Robbins book (not from the slides): 4 P a g e
5 Pay attention to these pieces of information: -The homeostasis between osteoblasts and osteoclasts in bones remodelling is a continuous and dynamic complex process even in adult mature skeleton, even in the microscopic level the intensity decreases with age but it won t stop never until die. - Peak bone mass is reached in early adulthood after completion of skeletal growth, then it decreases in the 4 th decade. Remember that this decrement differs from person to person according to factors mentioned earlier. -Bone Resorption > bone formation on 4th decade The things that increase (+) osteoclasts (decrease the bone mass) are Pth,IL-1 and steroids (given for a long time to treat immunological diseases, so these patients suffer from decrease in the bone mass and osteoporosis). And the things that decrease (-) osteoclasts (decrease bone resorption) are BMPs (bone morphogenic proteins) and sex hormones (oestrogen and test.) Some people suggest that we can treat osteoporosis in females by giving oestrogen hormone, but there are risks, such as: thromboembolism especially if the patient suffer from hypertension, so they use alternatives. This picture shows the paracrine molecular mechanism that regulate osteoclast formation and function. Osteoclasts are derived from the same mononuclear cells that differentiate into macrophages. Osteoblasts (stromal cells) membrane associated RANK ligand binds to its receptor RANK located on the cell surface of osteoclasts precursors. This interaction causes the precursor cells to produce functional osteoclasts. Osteoblasts also secrete osteoprotegerin (OPG), which act as decoy receptor for RANK ligand, preventing it from binding the RANK receptor on osteoclast precursors. Consequently. OPG prevents bone resorption by inhibiting osteoclast differentiation. 5 P a g e
6 There are two types of bone: woven bones and lamellar bones Woven bones are hyperactive, haphazard bones, they are replaced by lamellar bones in adults (remodelling process). The present of woven bones in adults is abnormal and indicates a pathological condition, such as: fracture and osteogenic sarcoma. The bone matrix is synthesized in one of two histologic forms, woven or lamellar. Woven bone (pic A) is produced more rapidly, such as during fetal development or fracture repair, but the haphazard arrangement of collagen fibers imparts less structural integrity than the parallel collagen fibers in slowly produced lamellar bone (pic B) Lamellar has less cells and they are osteocytes (less active). on the other hand, woven has osteoblasts which are more active. The picture show osteoblasts, where they synthesized osteoid (the pink material), either during growth or fracture repair. The picture show osteoclasts, multinucleated giant cells, they resorb bone. Look to the osteolytic bite (it s the space between osteoclasts and the bone) 6 P a g e
7 Remember: bone formation occurs by osteoblasts then remodelling occurs by osteoclasts Long bone structure: Its composed of two epiphyses at proximal and distal end and a diaphysis (shaft) between them, between epiphysis and metaphysis there is a layer of hyaline cartilage called growth plate/ epiphysial line, it s totally ossified in the adulthood (after you complete your skeleton maturation. The area between the growth plate and the diaphysis called metaphysis. Its important to know the structure as there are certain diseases especially tumors occurs particularly in metaphysis or diaphysis and so on. Hematopoietic process occurs in yellow bone marrow in the diaphysis. Flat bones, such as: sternum and skull differ in shape than long bones. The picture shows the steps of long bone formation by a process called endochondral ossification The picture shows the steps of flat bone formation by a process called intramembranous ossification. 7 P a g e
8 The picture shows the histology of articulating cartilage (growth plate), look to the: chondrocytes subchondral plate bone marrow Now lets start with pathology: The first type of disorders is congenital disorders. These disorders are born with the infant and divided into two major groups: -Dysostosis: it is characterized by abnormal condensation and migration of mesenchyme during growth, it results from genetic abnormalities (mutation) in homeobox genes, and stimulated by cytokines and its receptors, they are not common but they can occur: 1-Aplasia; means no growth. For example: aplasia in the distal phalanx or aplasia in tibia (the patient doesn t have tibia) 2-Supernumerary digits; here the patient have additional one or more digit. 3-Syndactaly and craniosynostosis; in Syndactaly digits are fused together and need a separation surgery, while in craniosynostosis abnormal formation for the skull sutures (missing sutures or abnormal) they affect brain growth. 8 P a g e
9 -Dysplasia Dysplasia in neoplasia means a precursor for malignancy. However in congenital disorders it means disorganized bone and cartilage results from genetic mutation which control the development and remodelling, some of them are common and some are not and they don t considered a premalignant condition. (it will be continued in the next lecture insallah). Pay attention to the pictures the doctor said that there will be questions about them in the exam. Sorry for any mistake Best of luck if you want to go fast go alone, but if you want to go far go together 9 P a g e
The Skeletal System:Bone Tissue
The Skeletal System:Bone Tissue Dynamic and ever-changing throughout life Skeleton composed of many different tissues cartilage, bone tissue, epithelium, nerve, blood forming tissue, adipose, and dense
More informationThe Skeletal System:Bone Tissue
The Skeletal System:Bone Tissue Dynamic and ever-changing throughout life Skeleton composed of many different tissues cartilage, bone tissue, epithelium, nerve, blood forming tissue, adipose, and dense
More informationFunctions of the Skeletal System. Chapter 6: Osseous Tissue and Bone Structure. Classification of Bones. Bone Shapes
Chapter 6: Osseous Tissue and Bone Structure Functions of the Skeletal System 1. Support 2. Storage of minerals (calcium) 3. Storage of lipids (yellow marrow) 4. Blood cell production (red marrow) 5. Protection
More informationBIOH111. o Cell Module o Tissue Module o Integumentary system o Skeletal system o Muscle system o Nervous system o Endocrine system
BIOH111 o Cell Module o Tissue Module o Integumentary system o Skeletal system o Muscle system o Nervous system o Endocrine system Endeavour College of Natural Health endeavour.edu.au 1 TEXTBOOK AND REQUIRED/RECOMMENDED
More informationCHAPTER 6 LECTURE OUTLINE
CHAPTER 6 LECTURE OUTLINE I. INTRODUCTION A. Bone is made up of several different tissues working together: bone, cartilage, dense connective tissue, epithelium, various blood forming tissues, adipose
More informationSKELETAL SYSTEM I NOTE: LAB ASSIGNMENTS for this topic will run over 3 Weeks. A SEPARATE WORKSHEET WILL BE PROVIDED.
BIO 211; Anatomy and Physiology I REFERENCE: CHAPTER 07 1 Dr. Lawrence Altman Naugatuck Valley Community College LECTURE TOPICS OUTLINE SKELETAL SYSTEM I NOTE: LAB ASSIGNMENTS for this topic will run over
More informationOSSEOUS TISSUE & BONE STRUCTURE PART I: OVERVIEW & COMPONENTS
OSSEOUS TISSUE & BONE STRUCTURE PART I: OVERVIEW & COMPONENTS The Skeletal System Skeletal system includes: bones of the skeleton, cartilages, ligaments, and connective tissues What are the functions of
More informationAn Introduction to the Skeletal System Skeletal system includes Bones of the skeleton Cartilages, ligaments, and connective tissues
An Introduction to the Skeletal System Skeletal system includes Bones of the skeleton Cartilages, ligaments, and connective tissues Functions of the Skeletal System Support Storage of minerals (calcium)
More informationKEY CONCEPTS Unit 6 THE SKELETAL SYSTEM
ANATOMY & PHYSIOLOGY 1 (101-805 - AB) PAUL ANDERSON 2011 KEY CONCEPTS Unit 6 THE SKELETAL SYSTEM A Overview of The Skeletal System 1. Definition: Anatomically the SKELETAL SYSTEM consists of bones, cartilages,
More informationChapter 6 Bones and Bone Tissue Chapter Outline
Chapter 6 Bones and Bone Tissue Chapter Outline Module 6.1: Introduction to Bones as Organs (Figures 6.1, 6.2, 6.3, 6.4) A. The skeletal system includes the bones, joints, and their associated supporting
More informationBONE TISSUE. Dr. Heba Kalbouneh Associate Professor of Anatomy and Histology
BONE TISSUE Dr. Heba Kalbouneh Associate Professor of Anatomy and Histology BONE FUNCTION Support Protection (protect internal organs) Movement (provide leverage system for skeletal muscles, tendons, ligaments
More informationThe Skeletal System PART A. PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College
PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College The Skeletal System 5 PART A The Skeletal System Parts of the skeletal system Bones (skeleton) Joints
More informationChapter 6: Skeletal System: Bones and Bone Tissue
Chapter 6: Skeletal System: Bones and Bone Tissue I. Functions A. List and describe the five major functions of the skeletal system: 1. 2. 3.. 4. 5.. II. Cartilage A. What do chondroblasts do? B. When
More informationThe Skeletal System. Chapter 7a. Skeletal System Introduction Functions of the skeleton Framework of bones The skeleton through life
The Skeletal System Skeletal System Introduction Functions of the skeleton Framework of bones The skeleton through life Chapter 7a Support Protection Movement Storage areas Minerals Lipids Hemopoiesis
More informationOsseous Tissue and Bone Structure
C h a p t e r 6 Osseous Tissue and Bone Structure PowerPoint Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright 2009 Pearson Education, Inc., publishing as Pearson Benjamin
More informationSKELETAL SYSTEM CHAPTER 07. Bone Function BIO 211: ANATOMY & PHYSIOLOGY I. Body Movement interacts with muscles bones act as rigid bar of a lever
Page 1 BIO 211: ANATOMY & PHYSIOLOGY I 1 CHAPTER 07 SKELETAL SYSTEM Dr. Lawrence G. G. Altman www.lawrencegaltman.com Some illustrations are courtesy of McGraw-Hill. Some illustrations are courtesy of
More informationSKELETAL SYSTEM CHAPTER 07 BIO 211: ANATOMY & PHYSIOLOGY I
BIO 211: ANATOMY & PHYSIOLOGY I 1 CHAPTER 07 SKELETAL SYSTEM Dr. Lawrence G. G. Altman www.lawrencegaltman.com Some illustrations are courtesy of McGraw-Hill. Some illustrations are courtesy of McGraw-Hill.
More informationChapter 6: Osseous Tissue and Bone Structure
Chapter 6: Osseous Tissue and Bone Structure I. An Introduction to the Skeletal System, p. 180 Objective: Describe the functions of the skeletal system The skeletal system includes: - bones of the skeleton
More informationTypes of Bones. 5 basic types of bones: Sutural bones - in joint between skull bones
The Skeletal System The Skeletal System Bone and their cartilage, ligaments & tendons. Dynamic and ever changing throughout life Skeleton contains all 4 tissue types; Epithelial, connective, muscle and
More informationBio 103 Skeletal System 45
45 Lecture Outline: SKELETAL SYSTEM [Chapters 7, 8] Introduction A. Components B. Functions 1. 2. 3. 4. Classification and Parts A. Bone Shapes 1. Long: 2. Short: 3. Flat: 4. Irregular: 5. Sesamoid: B.
More informationWhat are the parts of the skeletal system? Chapter 6- Part I Bones and Skeletal Tissues. Growth of Cartilage. Bones come in many shapes
Chapter 6- Part I Bones and Skeletal Tissues Components of the skeletal system Classification of Bone (bone shapes) Functions of bone Bone structure Microscopic structure of bone and bone cells What are
More informationANATOMY & PHYSIOLOGY - CLUTCH CH. 8 - BONE AND CARTILAGE.
!! www.clutchprep.com CONCEPT: BONE CLASSIFICATIONS There are four classifications of bones based on their 1. Long bones are greater in length than in width - Found in the upper and lower limbs (ex: arm,
More informationSKELETAL SYSTEM. Introduction Notes (pt 1)
SKELETAL SYSTEM Introduction Notes (pt 1) I. INTRODUCTION 1. Bones include active, living tissues: bone tissue, cartilage, dense connective tissue, blood, and nervous tissue. 2. Bones: support and protect
More informationSkeletal Tissues. Skeletal tissues. Frame; muscles, organs and CT attach. Brain, spinal cord, thoracic organs; heart and lungs.
Skeletal Tissues Functions 1) support 2) protection 3) movement Skeletal tissues Frame; muscles, organs and CT attach. Brain, spinal cord, thoracic organs; heart and lungs. Aids muscle contraction; generate
More informationSkeletal System. The skeletal System... Components
Skeletal System The skeletal System... What are the general components of the skeletal system? What does the skeletal system do for you & how does it achieve these functions? Components The skeletal system
More informationBones. The division of bones anatomically is : long, short, irregular, flat and sesamoid.
Bones Osteocytes : Are responsible for maintenance of bones Present in lacunae, and send processes. Unable to divide. The division of bones anatomically is : long, short, irregular, flat and sesamoid.
More informationThe Skeletal System Vertebral column Sacrum. Osseous tissue For the body and soft organs. Magnesium, sodium, fluoride Levers for muscle action
10/1/2016 Cranium Facial s Skull Clavicle Scapula Sternum Rib Humerus Vertebra Radius Ulna Carpals Thoracic cage (ribs and sternum) The Skeletal System Vertebral column Sacrum Phalanges Metacarpals Femur
More informationDue in Lab. Due next week in lab - Scientific America Article Select one article to read and complete article summary
Due in Lab 1. Skeletal System 33-34 2. Skeletal System 26 3. PreLab 6 Due next week in lab - Scientific America Article Select one article to read and complete article summary Cell Defenses and the Sunshine
More informationBIOL 2457 CHAPTER 6 SI 1. irregular ectopic: sutural (Wormian) The is between the shaft and end. It contains cartilage that is
BIOL 2457 CHAPTER 6 SI 1 1. List 5 functions of bones: 2. Classify bones according to shape: give descriptions and examples: long short flat irregular ectopic: sutural (Wormian) ectopic: sesamoid 3. The
More informationThe formation of blood cells is called. hemopoiesis. What does our bone store? Where do our bones store fat? yellow marrow.
What are the 5/6 functions of the skeletal system? support, protection, movement, blood cell formation, storage, homeostasis The formation of blood cells is called hemopoiesis What does our bone store?
More informationThe Skeletal System PART A
5 The Skeletal System PART A PowerPoint Lecture Slide Presentation by Jerry L. Cook, Sam Houston University ESSENTIALS OF HUMAN ANATOMY & PHYSIOLOGY EIGHTH EDITION ELAINE N. MARIEB The Skeletal System
More informationSkeletal Tissues Dr. Ali Ebneshahidi
Skeletal Tissues Dr. Ali Ebneshahidi Functions of Bones 1. Support and protection: Bones give shape to body structure. Bones provide support to body weight. Certain bones protect vital internal organs
More informationOssification and Bone Remodeling
Ossification and Bone Remodeling Pre-natal Ossification Embryonic skeleton: fashioned from fibrous membranes or cartilage to accommodate mitosis. 2 types of pre-natal ossification (bone formation) 1.
More informationPeggers Super Summaries Basic Sciences Bone
Bone Overview & Turnover BONES Function o Support o Protection o Assisting movement o Storage of minerals o Production of red blood cells from marrow Types o Cancellous o Compact with Haversian systems
More informationChp. 6: Bones and Skeletal Tissue Student Worksheet. 1. The skeletal system is composed of bones,,, and.
Chp. 6: Bones and Skeletal Tissue Student Worksheet 1. The skeletal system is composed of bones,,, and. 2. What are 5 functions of the skeletal system? 3. Besides osseous tissue (connective tissue with
More information-the emphasis on this section is the structure and function of bone tissue and on the dynamics of its formation and remodeling throughout life.
Biology 325 Fall 2004 BONES AND SKELETAL TISSUES Introduction -skeleton contains cartilage and bones -the emphasis on this section is the structure and function of bone tissue and on the dynamics of its
More informationBone Tissue- Chapter 5 5-1
Bone Tissue- Chapter 5 5-1 Bone Functions Support Protection Assistance in movement Mineral storage and release Blood cell production Triglyceride storage 5-2 Bone Chemistry Water (25%) Organic Constituent
More informationSKELETAL TISSUES CHAPTER 7 INTRODUCTION TO THE SKELETAL SYSTEM TYPES OF BONES
SKELETAL TISSUES CHAPTER 7 By John McGill Supplement Outlines: Beth Wyatt Original PowerPoint: Jack Bagwell INTRODUCTION TO THE SKELETAL SYSTEM STRUCTURE Organs: Bones Related Tissues: Cartilage and Ligaments
More informationSkeletal System worksheet
Skeletal System worksheet Name Section A: Intro to Skeletal System The skeletal system performs vital functions that enable us to move through our daily lives. Support - The skeleton provides support and
More informationNOTES: Skeletal System (Ch 5, part 1)
NOTES: Skeletal System (Ch 5, part 1) Individual bones are the organs of the skeletal system. A bone contains very active tissues. BONE STRUCTURE: *Bone structure reflects its function. Parts of a long
More informationPrinciples of Anatomy and Physiology
Principles of Anatomy and Physiology 14 th Edition CHAPTER 6 The Skeletal System: Bone Tissue Introduction The skeletal system has 6 important functions: Provides support Protects the internal organs (brain,
More informationFig Articular cartilage. Epiphysis. Red bone marrow Epiphyseal line. Marrow cavity. Yellow bone marrow. Periosteum. Nutrient foramen Diaphysis
Fig. 7.1 Articular cartilage Epiphysis Red bone marrow Epiphyseal line Marrow cavity Yellow bone marrow Nutrient foramen Diaphysis Site of endosteum Compact bone Spongy bone Epiphyseal line Epiphysis Articular
More informationChapter 6: SKELETAL SYSTEM
Chapter 6: SKELETAL SYSTEM I. FUNCTIONS A. Support B. Protection C. Movement D. Mineral storage E. Lipid storage (Fig. 6.8b) F. Blood cell production (Fig. 6.4) II. COMPONENTS A. Cartilage 1. Hyaline 2.
More informationSkeletal Tissue Study Slides. Chapter 6
Skeletal Tissue Study Slides Chapter 6 Functions of the skeletal system include all of the following, except A. support. B. storage. C. protection. D. blood cell production. E. movement. ANSWER Functions
More informationSkeletal Tissues. Dr. Ali Ebneshahidi
Skeletal Tissues Dr. Ali Ebneshahidi Functions of Bones 1. Support and protection : Bones give shape to body structure. Bones provide support to body weight. Certain bones protect vital internal organs
More informationDr. Heba Kalbouneh. Saba Alfayoumi. Heba Kalbouneh
11 Dr. Heba Kalbouneh Saba Alfayoumi Heba Kalbouneh 2- Bone Bone tissue is also classified into primary bone and secondary bone. In the beginning, the first bone that is deposited by the osteoblasts is
More informationHuman Anatomy & Physiology
PowerPoint Lecture Slides prepared by Barbara Heard, Atlantic Cape Community College Ninth Edition Human Anatomy & Physiology C H A P T E R 6 Annie Leibovitz/Contact Press Images 2013 Pearson Education,
More informationSkeletal System. Chapter 6.1 Human Anatomy & Physiology
Skeletal System Chapter 6.1 Human Anatomy & Physiology Overview of Skeletal System Bones Joints Skeletal System Cartilage Tendons (bone to muscle) Ligaments (bone to bone) Function of the Skeletal System
More informationChapter 5 The Skeletal System
Chapter 5 The Skeletal System The Skeletal System Parts of the skeletal system Bones (skeleton) Joints Cartilages Ligaments (bone to bone)(tendon=bone to muscle) Divided into two divisions Axial skeleton:
More informationFunctions of the Skeletal System
SKELETAL SYSTEM Functions of the Skeletal System Support: Internal framework that supports and anchors all soft organs. Protection: Bones protect soft body organs Body movement skeletal muscle attached
More informationWhat is bone? Specialized form of connective tissue: mineralized collagen matrix, therefore very rigid and strong while still retaining some degree of
Bone What is bone? Specialized form of connective tissue: mineralized collagen matrix, therefore very rigid and strong while still retaining some degree of flexibility Other types of connective tissue:
More informationBiology. Dr. Khalida Ibrahim
Biology Dr. Khalida Ibrahim BONE TISSUE Bone tissue is a specialized form of connective tissue and is the main element of the skeletal tissues. It is composed of cells and an extracellular matrix in which
More informationDo Now: 1. Where, specifically, is blood created? Which part of the long bone? 2. Which structures are primarily associated with growth? 3.
Do Now: 1. Where, specifically, is blood created? Which part of the long bone? 2. Which structures are primarily associated with growth? 3. How could damage to these areas impact bone growth? WRITE AND
More informationChapter 7. Skeletal System
Chapter 7 Skeletal System 1 Introduction: A. Bones are very active, living tissues B. Each bone is made up of several types of tissues and so is an organ. C. Bone functions include: muscle attachment,
More informationFor more information about how to cite these materials visit
Author(s): University of Michigan Medical School, Department of Cell and Developmental Biology License: Unless otherwise noted, the content of this course material is licensed under a Creative Commons
More informationModule 2:! Functional Musculoskeletal Anatomy A! Semester 1! !!! !!!! Hard Tissues, Distal Upper Limb & Neurovascular Supply of Upper Limb!
Functional Musculoskeletal Anatomy A Module 2: Hard Tissues, Distal Upper Limb & Neurovascular Supply of Upper Limb Semester 1 1 18. Bone Tissue & Growth of Bones 18.1 Describe the structure of bone tissue
More informationOutline. Skeletal System. Functions of Bone. Bio 105: Skeletal System 3/17/2016. The material from this lecture packet will be on the lecture exam
Bio 105: Skeletal System Lecture 8 Chapter 5 The material from this lecture packet will be on the lecture exam The identification that you do after this lecture will be on the lab exam Outline I. Overview
More informationOssification = Osteogenesis
Ossification = Osteogenesis Ossification = Osteogenesis Parts of the fetal skeleton form during the first few weeks after conception By the end of the 8 th week, the skeletal pattern is formed : cartilage
More informationBones are made of OSSEOUS TISSUE
SKELETAL SYSTEM Functions of the Skeletal System Bones are made of OSSEOUS TISSUE Support and Protection Body movement Blood cell formation (bone marrow) Storage of inorganic materials (salt, calcium,
More informationChapter 6 & 7 The Skeleton
Chapter 6 & 7 The Skeleton Try this Make clockwise circles with your RIGHT foot, while doing this, draw the number 6 in the air with you RIGHT hand what happens to your foot???? Bony Background Adult body
More informationOsteology. Dr. Carmen E. Rexach Anatomy 35 Mt San Antonio College
Osteology Dr. Carmen E. Rexach Anatomy 35 Mt San Antonio College Functions of the Skeletal System: Support Movement Protection Hemopoiesis Electrolyte balance (Ca ++ /PO -3 4 ) Acid-base balance Storage
More informationBone Development. Two Types of OssificaDon 10/18/14. Osteogenesis ( ) bone Dssue formadon Stages. Bones and Skeletal Tissues: Part B
Bone Development 6 Bones and Skeletal Tissues: Part B Osteogenesis ( ) bone Dssue formadon Stages Bone formadon begins in the 2nd month of development Postnatal bone growth undl early adulthood Bone remodeling
More informationOsseous Tissue and Bone Structure
6 Osseous Tissue and Bone Structure PowerPoint Lecture Presentations prepared by Jason LaPres Lone Star College North Harris An Introduction to the Skeletal System Learning Outcomes 6-1 Describe the primary
More informationChapter 5 The Skeletal System:Bone Tissue. Functions of Bone. Bones
Chapter 5 The Skeletal System:Bone Tissue Dynamic and ever-changing throughout life Skeleton composed of many different tissues cartilage, bone tissue, epithelium, nerve, blood forming tissue, adipose,
More informationOsseous Tissue and Bone Structure
6 Osseous Tissue and Bone Structure PowerPoint Lecture Presentations prepared by Jason LaPres Lone Star College North Harris An Introduction to the Skeletal System Learning Outcomes 6-1 Describe the primary
More informationb. Adult bones produce 2.5 million RBCs each second.
Ch 6 Skeletal System I. Functions of the Skeletal System A. The skeletal system consists of: 1. bones, cartilage, tendons and ligaments B. Living bone is not Gr. dried up 1. It is dynamic and adaptable
More informationChapter 5-Skeletal System
Chapter 5-Skeletal System The Skeletal System Bones Function in Support, Movement, Protection, Storage, and Blood Cell Production (p. 83) Bones Have a Hard Outer Layer Surrounding Spongy Bone (pp. 83-84)
More informationCHAPTER IV PDL 101 HUMAN ANATOMY & PHYSIOLOGY
CHAPTER IV PDL 101 HUMAN ANATOMY & PHYSIOLOGY Ms. K. GOWRI. M.Pharm., Lecturer. BONES AND JOINTS Structure and function of bone(skeleton): Bone is a strong and durable type of connective tissue. It consists
More informationBone (2) Chapter 8. The bone is surrounded by the periosteum, the periosteum consists of two layers: a fibrous outer layer and an innercellular layer.
Bone (2) Chapter 8 The bone is surrounded by the periosteum, the periosteum consists of two layers: a fibrous outer layer and an innercellular layer. The innercellular layer contains osteoprogenitor cells,
More informationLecture 2: Skeletogenesis
Jilin University School of Stomatology Skeletogenesis Lecture 2: Skeletogenesis Aug. 18, 2015 Yuji Mishina, Ph.D. mishina@umich.edu Student will describe Development of Bone - the general anatomy of bone
More informationDr. Heba Kalbouneh. Dr. Heba Kalbouneh. Dr. Heba Kalbouneh
Dr. Heba Kalbouneh Dr. Heba Kalbouneh Dr. Heba Kalbouneh Bone Special connective tissue. Cartilages + Bones = Skeleton. Osseous = refers to bone. Functions of the bone: 1. Support: It forms the framework
More informationFORMATION OF BONE. Intramembranous Ossification. Bone-Lec-10-Prof.Dr.Adnan Albideri
FORMATION OF BONE All bones are of mesodermal origin. The process of bone formation is called ossification. We have seen that formation of most bones is preceded by the formation of a cartilaginous model,
More informationSkeletal System worksheet
Skeletal System worksheet Name Section A: Intro to Skeletal System The skeletal system performs vital functions that enable us to move through our daily lives. Support - The skeleton provides support and
More informationSheets 16&17. Dr. Heba Kalbouneh. Dr. Heba Kalbouneh. Dr. Heba Kalbouneh
Sheets 16&17 Dr. Heba Kalbouneh Dr. Heba Kalbouneh Dr. Heba Kalbouneh Ossification (formation of bone) - Osteoblasts are responsible for producing the extracellular matrix of the bone and these osteoblasts
More informationBone. Development. Tim Arnett. University College London. Department of Anatomy and Developmental Biology
Bone Development Tim Arnett Department of Anatomy and Developmental Biology University College London Bone development Outline Bone composition matrix + mineral Bone formation - intramembranous & endochondral
More informationFunctions of the Skeletal System
SKELETAL SYSTEM Functions of the Skeletal System Bones are made of OSSEOUS TISSUE Support and Protection Body movement Blood cell formation (bone marrow) - hemopoiesis Storage of inorganic materials (salt,
More informationAwaisheh. Mousa Al-Abbadi. Abdullah Alaraj. 1 Page
f #3 Awaisheh Abdullah Alaraj Mousa Al-Abbadi 1 Page *This sheet was written from Section 1 s lecture, in the first 10 mins the Dr. repeated all the previous material relating to osteoporosis from the
More informationPowerPoint Lecture Slides. Prepared by Patty Bostwick-Taylor, Florence-Darlington Technical College. The Skeletal System Pearson Education, Inc.
PowerPoint Lecture Slides Prepared by Patty Bostwick-Taylor, Florence-Darlington Technical College CHAPTER 5 The Skeletal System 2012 Pearson Education, Inc. Title Classification of Bones and Gross Anatomy
More informationRegulation of the skeletal mass through the life span
Regulation of the skeletal mass through the life span Functions of the skeletal system Mechanical protection skull Movement leverage for muscles Mineral metabolism calcium store Erythropoiesis red blood
More informationHole s Human Anatomy and Physiology Eleventh Edition. Mrs. Hummer. Chapter 7 Skeletal System
Hole s Human Anatomy and Physiology Eleventh Edition Mrs. Hummer Chapter 7 Skeletal System 1 Chapter 7 Skeletal System Bone Classification Long Bones Short Bones Flat Bones Irregular Bones Sesamoid (Round)
More information36 1 The Skeletal System Slide 1 of 40
1 of 40 The Skeleton All organisms need structural support. Unicellular organisms have a cytoskeleton. Multicellular animals have either an exoskeleton (arthropods) or an endoskeleton (vertebrates). 2
More informationAbdullah Alaraj. Mousa al abbadi. Mohammad Alfarra. 1 Page
f #2 Abdullah Alaraj Mohammad Alfarra Mousa al abbadi 1 Page introduction to what we will cover: -dysostosis is caused by genetic abnormalities in homeobox genes, cytokines and its receptors. However,
More informationOpenStax-CNX module: m Bone Structure * Ildar Yakhin. Based on Bone Structure by OpenStax. Abstract
OpenStax-CNX module: m63474 1 Bone Structure * Ildar Yakhin Based on Bone Structure by OpenStax This work is produced by OpenStax-CNX and licensed under the Creative Commons Attribution License 4.0 By
More informationHuman Biology Chapter 15.3: Bone Structure *
OpenStax-CNX module: m58082 1 Human Biology Chapter 15.3: Bone Structure * Willy Cushwa Based on Bone Structure by OpenStax This work is produced by OpenStax-CNX and licensed under the Creative Commons
More informationAnatomy & Physiology
Anatomy & Physiology 101-805 Unit 6 The Skeletal System Paul Anderson 2011 Skeletal System: Components Bones major organs of system, have all functions of system. Cartilages connect & protect bones at
More informationChapter 6 Skeletal System
Chapter 6 Skeletal System Functions of the skeletal system/bone 1. Support skeletal system is the internal framework of the body 2. Protection protects internal organs 3. Movement muscles & bones work
More informationSkeletal System Functions
Chapter 6 Skeletal System: Bones and Bone Tissue 6-1 Skeletal System Functions Support. Bone is hard and rigid; cartilage is flexible yet strong. Cartilage in nose, external ear, thoracic cage and trachea.
More informationChapter 6 Part B Bones and Skeletal Tissue
Chapter 6 Part B Bones and Skeletal Tissue 6.5 Bone Development Ossification (osteogenesis) is the process of bone tissue formation Formation of bony skeleton begins in month 2 of development Postnatal
More informationDerived copy of Bone *
OpenStax-CNX module: m57739 1 Derived copy of Bone * Shannon McDermott Based on Bone by OpenStax This work is produced by OpenStax-CNX and licensed under the Creative Commons Attribution License 4.0 By
More informationChapter 6. Bone Tissue
Chapter 6 Bone Tissue Functions of the Skeleton support hold the body up, supports muscles, mandible and maxilla support teeth protection brain, spinal cord, heart, lungs movement limb movements, breathing,
More informationSkeletal System. Bio 105
Skeletal System Bio 105 Outline I. Overview of the skeletal system II. Function of bones III. Bone structure IV. Bone cells V. Cartilage VI. Tendons and Ligaments VII. Joints VIII. Bone development IX.
More informationOutline. Skeletal System. Tendons link the skeletal and the muscular systems.
Outline Skeletal System Bio 105 I. Overview of the skeletal system II. Function of bones III. Bone structure IV. Bone cells V. Cartilage VI. Tendons and Ligaments VII. Joints VIII. Bone development IX.
More informationThe Skeletal System. The Axial Skeleton. The Appendicular Skeleton 2/6/ vertebral column. 1 hyoid (horseshoe shaped bone at base of chin)
The Skeletal System PSK 4U Mr. S. Kelly North Grenville DHS The Axial Skeleton 26 vertebral column 1 hyoid (horseshoe shaped bone at base of chin) 22 skull 25 ribs and sternum = 74 bones The Appendicular
More informationBone Formation, Growth, and Remodeling
Bone Formation, Growth, and Remodeling Pre-natal Ossification Embryonic skeleton: fashioned from fibrous membranes or cartilage to accommodate mitosis. 2 types of pre-natal ossification (bone formation)
More information2 PROCESSES OF BONE OSSIFICATION
2 PROCESSES OF BONE OSSIFICATION ENDOCHONDRAL OSSIFICATION 6 STEPS 1. CARTILAGE ENLARGES, BY APPOSITIONAL GROWTH; CHONDROCYTES AT CENTER OF CARTILAGE GROW IN SIZE; MATRIX REDUCES IN SIZE & SPICULES CALCIFY;
More informationSupport and protection. Body movement. Blood cell formation = hemopoiesis (occurs in bone marrow)
SKELETAL SYSTEM Functions of the Skeletal System Support and protection Body movement Blood cell formation = hemopoiesis (occurs in bone marrow) Storage of inorganic materials (salt, calcium, potassium.)
More informationThe Skeletal System. PSK 4U Mr. S. Kelly North Grenville DHS
The Skeletal System PSK 4U Mr. S. Kelly North Grenville DHS The Axial Skeleton 26 vertebral column 1 hyoid (horseshoe shaped bone at base of chin) 22 skull 25 ribs and sternum = 74 bones The Appendicular
More informationFigure ) The area that causes the lengthwise growth of a long bone is indicated by letter. Diff: 2 Page Ref:
Essentials of Anatomy and Physiology, 9e (Marieb) Chapter 5 The Skeletal System Short Answer Figure 5.1 Using Figure 5.1, identify the following: 1) Spongy bone is indicated by letter. Diff: 1 Page Ref:
More information