(ASO) 17. ( Antistreptolysin o) Downloaded from jmj.jums.ac.ir at 20: on Friday March 22nd 2019 [ DOI: /jmj.2.2.

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1 (ASO) * : :... : ( Antistreptolysin o) 2... : (%50). TODD 250 (%63/63) (P<0/05) :.. : : -* 83/2/4 83//5

2 : 2...()..(2) %/9 ( A.S.O). A.S.O.(3).(5 4) : A.S.O A.S.O ( ).. : A.S.O. 8/3 7/7 (%59/) (%22/7) (%59/) (%40/9) 9 (%47) 8 (%29/5) 5 A (%23/5) 4.. TODD 250 A.S.O 22 ( %63/63) ( )250 ( 3) 833 TODD A.S.O. TODD A.S.O. TODD A.S.O.( P< 0/05 ) ( 9). (%50) ret ridge. :..(6).(7)..(8) Antistreptolysin O liter (A.S.O)

3 .(9) A T M.() ( ) PMN.(8).(8) A.S.O %7/3 %54/5.() 200 ( 3 ) 2 ( 34 ).(3) ( 35 ) 3 %2 CohenTervaert : %86 %88 %22 %45 %38 %8 A.S.O.(4) 20 8/ () 200 : % %7 %8.(2) 9.(4) (3).(5) properdin 2-Norrline 3- Cohen Tervaert

4 REFERENCES: -Camp RDR: Psoriasis.In : Champion RH, Burton JL, Ebling FJG: Textbook of Dermatology. 5 th ed. London : Blackwell Science; 998: Ingram JT. The significance and management of psoriasis. Br Med J: 954 ; Tervaert WCC, Esseveld H. A study of the incidence of hemolytic streptococci in the throat in patients with psoriasis vulgaris. with reference to their role in the pathogenesis of this disease. Dermatologica :970 ; 40: Whyte HJ, Baugham RD. Acute guttate psoriasis and streptococcal infection. Arch Dermatol : Rosenberg EN, Noah PW, Zanolli MD et al. Use of rifampin with penicillin and erythromycin in the treatment of psoriasis. J Am Acad Dermatol :986; 4: Michelson EH. Unusual in psoriasis. Arch Dermatol: 985; l 78: Wannameker LW. Differences between streptococcal infections of the throat and of the skin. N Engl J M :970; 7: Janes R, Chalmers G, Ive F A. Is acute guttate psoriasis with renal disease a rarity? Arch Dermatol: 982 ; 8:4. 9-Nusbaum B P, Edwards E K, Horwitz S N. Psoriasis therapy. Arch Dermatol : 983 ; 9: Anderson T F, Voorhees J. Metabolic aspects of psoriasis. Post graduate Med :980 ; 67: White HJ, Banghman RD. Acute guttate psoriasis and streptococcal infection. Arch Dermatol: 964; 89: Blok S, Vissers W, Van Duijnhoven M, et al. Aggravation of psoriasis by infections: a constitutional trait or a variable expression? Eur J Dermatol: 2004 ; 4(4): Koca R, Altinyazar HC, Numanoglu G, Unalacak M. Guttate psoriasis-like lesions following BCG vaccination. J Trop Peditar: 2004 ; 50(3): Sandhu K, Jain R, Kaur I, Kumar B. Role of Pityrosporum ovale in guttate psoriasis. J Dermatol: 2003 ; 30(3): Gudjonsson JE, Thorarinsson AM, Sigurgeirsson B, Kristinsson KG, Valdimarsson H. Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study. Br J Dermatol: 2003 ;49(3):

5 EVALUATION OF THE RELATIONSHIP OF STREPTOCOCCAL INFECTIONS AND A.S.O TITRE IN GUTTATE PSORIASIS Abstract Salmanpour R (MD) Aghaei SH.( MD) Intruduction: Guttate psoriasis is a disease characterized by round to oval shaped lesions with silvery or gray scales on an erythematous base and several millimeters to one centimeter in diameter. Its lesions are generalized, discrete and distributed predominantly on the trunk and proximal extremities and occasionally on face, ears, scalp and rarely on palms and soles. The disease is predominantly seen in children and young adults. It seems that focal streptococcal infections have an effective role in the development of disease.this study was performed in order to determine the relationship of streptococcal infections and A.S.O titer prior to treatment.in 7 patients, throat culture was done and in all of patients the history of upper respiratory tract infection was questioned period. of illness, sex and age of the patients were recorded and the data were analyzed. Method: During 2 years, we selected 22 patients with guttate psoriasis. All of them were biopsies and A.S.O titre prior to treatment.in 7 patients, throat culture was done and in all of patients the history of upper respiratory tract infection was questioned.period of illness, sex and age of the patients were recorderd and the data were analyzed. Results: Fourteen out of 22 cases (63.63%) had an A.S.O titer equal to grater than 250 TODD units prior to treatment.eleven cases (50%) had a history of upper respiratory tract infection two weeks before illness. Conclusion: It seems that streptococcal infections play an effective role in the development of disease. It is necessary that throat culture and A.S.O titer be checked in these patients and suitable antibiotics was prescribed. Keywords: streptococcal infections, A.S.O titer, guttate psoriasis