Sandwell and West Birmingham Hospitals NHS Trust

Transcription

1 Sandwell and West Birmingham Hospitals NHS Trust Sandwell and West Birmingham Clinical Commissioning Group The drugs contained in the formulary of Sandwell and West Birmingham Hospitals Trust are listed below. NICE considers that the benefits of a local formulary include improving patient outcomes by optimising the use of medicines; supporting the inclusion of patient factors in decision-making about medicines; improving local care pathways; improving collaboration between clinicians and commissioners; improving quality by reducing inappropriate variations in clinical care; improving quality through access to cost-effective medicines; supporting the supply arrangements of medicines across a local health economy; supporting financial management and expenditure on medicines across health communities; supporting prescribers to follow guidance published by professional regulatory bodies in relation to medicines and prescribing. Drugs marked in black text are available for general use and may be prescribed by any prescriber in the Trust Drugs marked in orange as restricted are available for use in restricted circumstances; they may be restricted to certain specialties, or for treating certain diseases, or for use when first-line treatment has not worked. Where clinically appropriate, prescribing of restricted drugs may be passed to primary care on the advice of a specialist. Drugs which are approved by NICE in a technology appraisal are available for use in the Trust. All other drugs are available on Consultant request provided the request is authorized by a medical director or an officer of the Drug and Therapeutics committee.

2 1 Gastro-intestinal system->1.1 Dyspepsia and gastro-oesophageal reflux disease->1.1.1 Antacids and simeticone->aluminium- and magnesium-containing antacids ALUMINIUM HYDROXIDE On 1 Gastro-intestinal system->1.1 Dyspepsia and gastro-oesophageal reflux disease->1.1.1 Antacids and simeticone->aluminium- and magnesium-containing antacids MAGNESIUM TRISILICATE On 1 Gastro-intestinal system->1.1 Dyspepsia and gastro-oesophageal reflux disease->1.1.1 Antacids and simeticone->aluminium- and magnesium-containing antacids->aluminium HYDROXIDE Co-magaldrox On 1 Gastro-intestinal system->1.1 Dyspepsia and gastro-oesophageal reflux disease->1.1.1 Antacids and simeticone->aluminium- and magnesium-containing antacids->aluminium HYDROXIDE->Comagaldrox Maalox On 1 Gastro-intestinal system->1.1 Dyspepsia and gastro-oesophageal reflux disease->1.1.1 Antacids and simeticone->aluminium- and magnesium-containing antacids->magnesium TRISILICATE Magnesium Trisilicate Mixture, BP On 1 Gastro-intestinal system->1.1 Dyspepsia and gastro-oesophageal reflux disease->1.1.1 Antacids and simeticone->simeticone alone Infacol Restricted 1 Gastro-intestinal system->1.1 Dyspepsia and gastro-oesophageal reflux disease->1.1.2 Compound alginates and proprietary indigestion preparations->alginate raft-forming oral suspensions Peptac On 1 Gastro-intestinal system->1.1 Dyspepsia and gastro-oesophageal reflux disease->1.1.2 Compound alginates and proprietary indigestion preparations->other compound alginate preparations Gaviscon Infant Restricted 1 Gastro-intestinal system->1.2 Antispasmodics and other drugs altering gut motility Motility stimulants On 1 Gastro-intestinal system->1.2 Antispasmodics and other drugs altering gut motility->antimuscarinics ATROPINE SULFATE On 1 Gastro-intestinal system->1.2 Antispasmodics and other drugs altering gut motility->antimuscarinics HYOSCINE BUTYLBROMIDE On 1 Gastro-intestinal system->1.2 Antispasmodics and other drugs altering gut motility->antimuscarinics->atropine SULFATE Atropine On 1 Gastro-intestinal system->1.2 Antispasmodics and other drugs altering gut motility->antimuscarinics->hyoscine BUTYLBROMIDE Buscopan On 1 Gastro-intestinal system->1.2 Antispasmodics and other drugs altering gut motility->other antispasmodics MEBEVERINE HYDROCHLORIDE On 1 Gastro-intestinal system->1.2 Antispasmodics and other drugs altering gut motility->other antispasmodics PEPPERMINT OIL On 1 Gastro-intestinal system->1.2 Antispasmodics and other drugs altering gut motility->other antispasmodics->mebeverine HYDROCHLORIDE Mebeverine Hydrochloride On 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.1 H2-receptor antagonists RANITIDINE On 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.1 H2-receptor antagonists->ranitidine Ranitidine On 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.4 Prostaglandin analogues MISOPROSTOL Restricted

3 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.5 Proton pump inhibitors LANSOPRAZOLE On 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.5 Proton pump inhibitors OMEPRAZOLE Restricted 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.5 Proton pump inhibitors->lansoprazole Lansoprazole On 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.5 Proton pump inhibitors->lansoprazole Zoton Restricted 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.5 Proton pump inhibitors->omeprazole Omeprazole On 1 Gastro-intestinal system->1.3 Antisecretory drugs and mucosal protectants->1.3.5 Proton pump inhibitors->omeprazole Losec Restricted 1 Gastro-intestinal system->1.4 Acute diarrhoea->1.4.2 Antimotility drugs CODEINE PHOSPHATE On 1 Gastro-intestinal system->1.4 Acute diarrhoea->1.4.2 Antimotility drugs LOPERAMIDE HYDROCHLORIDE On 1 Gastro-intestinal system->1.4 Acute diarrhoea->1.4.2 Antimotility drugs MORPHINE On 1 Gastro-intestinal system->1.4 Acute diarrhoea->1.4.2 Antimotility drugs->loperamide HYDROCHLORIDE Imodium On 1 Gastro-intestinal system->1.4 Acute diarrhoea->1.4.2 Antimotility drugs->loperamide HYDROCHLORIDE Loperamide On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates MESALAZINE On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates SULFASALAZINE On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates BALSALAZIDE SODIUM Restricted 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates->BALSALAZIDE SODIUM Colazide Restricted 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates->MESALAZINE Asacol On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates->MESALAZINE Asacol MR On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates->MESALAZINE Pentasa On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates->MESALAZINE Salofalk On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.1 Aminosalicylates->SULFASALAZINE Sulfasalazine On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.2 Corticosteroids PREDNISOLONE On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.2 Corticosteroids BUDESONIDE Restricted 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.2 Corticosteroids->PREDNISOLONE->Rectal preparations Predsol On 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.3 Drugs affecting the immune response AZATHIOPRINE Restricted 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.3 Drugs affecting the immune response->cytokine modulators ADALIMUMAB Restricted 1 Gastro-intestinal system->1.5 Chronic bowel disorders->1.5.3 Drugs affecting the immune response->cytokine modulators- >INFLIXIMAB Preparations Restricted

4 1 Gastro-intestinal system->1.6 Laxatives->1.6.1 Bulk-forming laxatives ISPAGHULA HUSK On 1 Gastro-intestinal system->1.6 Laxatives->1.6.1 Bulk-forming laxatives METHYLCELLULOSE On 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives DOCUSATE SODIUM On 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives GLYCEROL On 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives SENNA On 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives SODIUM PICOSULFATE On 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives DANTRON Restricted 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives- >DANTRON 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives- >DANTRON With docusate sodium (as codanthrusate) With poloxamer?188? (as codanthramer) Restricted Restricted 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives- >DANTRON->With docusate sodium (as co-danthrusate) Co-danthrusate Restricted 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives- >DANTRON->With poloxamer?188?(as co-danthramer) Co-danthramer Restricted 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives- >GLYCEROL Glycerol Suppositories, BP On 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives- >SENNA Senna On 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives- >SENNA Senokot On 1 Gastro-intestinal system->1.6 Laxatives->1.6.2 Stimulant laxatives- >SODIUM PICOSULFATE Sodium Picosulfate On 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives LACTULOSE On 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives PHOSPHATES (RECTAL) On 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives SODIUM CITRATE (RECTAL) On 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives MACROGOLS Restricted 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives- >LACTULOSE Lactulose On 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives- >MACROGOLS Movicol Restricted 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives- >MACROGOLS Movicol Paediatric Restricted 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives- >PHOSPHATES (RECTAL) Fleet Ready-to-use Enema On 1 Gastro-intestinal system->1.6 Laxatives->1.6.4 Osmotic laxatives- >SODIUM CITRATE (RECTAL) Relaxit Micro-enema On 1 Gastro-intestinal system->1.6 Laxatives->1.6.5 Bowel cleansing preparations->macrogols Klean-Prep On 1 Gastro-intestinal system->1.6 Laxatives->1.6.5 Bowel cleansing preparations->phosphates (ORAL) Fleet Phospho-soda On

5 1 Gastro-intestinal system->1.6 Laxatives->1.6.5 Bowel cleansing preparations->sodium PICOSULFATE WITH MAGNESIUM CITRATE Picolax Restricted 1 Gastro-intestinal system->1.6 Laxatives->1.6.7 Other drugs used in constipation PRUCALOPRIDE NICE-approved 1 Gastro-intestinal system->1.7 Local preparations for anal and rectal disorders Management of anal fissures Restricted 1 Gastro-intestinal system->1.7 Local preparations for anal and rectal disorders Rectal sclerosants Restricted 1 Gastro-intestinal system->1.7 Local preparations for anal and rectal disorders->1.7.2 Compound haemorrhoidal preparations with corticosteroids Anusol-HC On 1 Gastro-intestinal system->1.7 Local preparations for anal and rectal disorders->1.7.3 Rectal sclerosants PHENOL Restricted 1 Gastro-intestinal system->1.7 Local preparations for anal and rectal disorders->1.7.3 Rectal sclerosants->phenol Oily Phenol Injection, BP Restricted 1 Gastro-intestinal system->1.7 Local preparations for anal and rectal disorders->1.7.4 Management of anal fissures GLYCERYL TRINITRATE Restricted 1 Gastro-intestinal system->1.7 Local preparations for anal and rectal disorders->1.7.4 Management of anal fissures->glyceryl TRINITRATE Rectogesic Restricted 1 Gastro-intestinal system->1.9 Drugs affecting intestinal secretions Bile acid sequestrants On 1 Gastro-intestinal system->1.9 Drugs affecting intestinal secretions- >1.9.1 Drugs affecting biliary composition and flow URSODEOXYCHOLIC ACID On 1 Gastro-intestinal system->1.9 Drugs affecting intestinal secretions- >1.9.1 Drugs affecting biliary composition and flow- >URSODEOXYCHOLIC ACID Ursodeoxycholic Acid On 1 Gastro-intestinal system->1.9 Drugs affecting intestinal secretions- >1.9.2 Bile acid sequestrants COLESTYRAMINE On 1 Gastro-intestinal system->1.9 Drugs affecting intestinal secretions- >1.9.4 Pancreatin->PANCREATIN Creon 10?000 On 1 Gastro-intestinal system->1.9 Drugs affecting intestinal secretions- >1.9.4 Pancreatin->PANCREATIN Pancrex V On 1 Gastro-intestinal system->1.9 Drugs affecting intestinal secretions- >1.9.4 Pancreatin->PANCREATIN Higher-strength preparations Restricted 1 Gastro-intestinal system->1.9 Drugs affecting intestinal secretions- >1.9.4 Pancreatin->PANCREATIN->Higher-strength preparations Creon Restricted 2 Cardiovascular system->2.1 Positive inotropic drugs->2.1.1 Cardiac glycosides DIGOXIN On 2 Cardiovascular system->2.1 Positive inotropic drugs->2.1.1 Cardiac glycosides Digoxin-specific antibody Restricted 2 Cardiovascular system->2.1 Positive inotropic drugs->2.1.1 Cardiac glycosides->digoxin Digoxin On 2 Cardiovascular system->2.1 Positive inotropic drugs->2.1.2 Phosphodiesterase type-3 inhibitors ENOXIMONE Restricted 2 Cardiovascular system->2.1 Positive inotropic drugs->2.1.2 Phosphodiesterase type-3 inhibitors->enoximone Perfan Restricted 2 Cardiovascular system->2.10 Stable angina, acute coronary syndromes, and fibrinolysis-> Fibrinolytic drugs STREPTOKINASE On 2 Cardiovascular system->2.10 Stable angina, acute coronary syndromes, and fibrinolysis-> Fibrinolytic drugs ALTEPLASE Restricted 2 Cardiovascular system->2.10 Stable angina, acute coronary syndromes, and fibrinolysis-> Fibrinolytic drugs TENECTEPLASE Restricted

6 2 Cardiovascular system->2.10 Stable angina, acute coronary syndromes, and fibrinolysis-> Fibrinolytic drugs UROKINASE Restricted 2 Cardiovascular system->2.11 Antifibrinolytic drugs and haemostatics TRANEXAMIC ACID On 2 Cardiovascular system->2.11 Antifibrinolytic drugs and haemostatics->blood-related products FRESH FROZEN PLASMA On 2 Cardiovascular system->2.11 Antifibrinolytic drugs and haemostatics->tranexamic ACID Tranexamic acid On 2 Cardiovascular system->2.12 Lipid-regulating drugs->bile acid sequestrants COLESTYRAMINE On 2 Cardiovascular system->2.12 Lipid-regulating drugs->bile acid sequestrants->colestyramine Colestyramine On 2 Cardiovascular system->2.12 Lipid-regulating drugs->ezetimibe EZETIMIBE Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->fibrates CIPROFIBRATE Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->fibrates FENOFIBRATE Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->fibrates- >FENOFIBRATE Fenofibrate Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->fibrates- >FENOFIBRATE Lipantil Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->fibrates- >FENOFIBRATE Supralip 160 Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->nicotinic acid group NICOTINIC ACID Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->nicotinic acid group->nicotinic ACID Modified release Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->omega-3 fatty acid compounds OMEGA-3-ACID ETHYL ESTERS Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->omega-3 fatty acid compounds->omega-3-acid ETHYL ESTERS Omacor Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->statins SIMVASTATIN On 2 Cardiovascular system->2.12 Lipid-regulating drugs->statins ATORVASTATIN Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->statins ROSUVASTATIN Restricted 2 Cardiovascular system->2.12 Lipid-regulating drugs->statins- >SIMVASTATIN Simvastatin On 2 Cardiovascular system->2.13 Local sclerosants ETHANOLAMINE OLEATE Restricted 2 Cardiovascular system->2.13 Local sclerosants SODIUM TETRADECYL SULFATE Restricted 2 Cardiovascular system->2.13 Local sclerosants->ethanolamine OLEATE Ethanolamine Oleate Restricted 2 Cardiovascular system->2.2 Diuretics->2.2.1 Thiazides and related diuretics BENDROFLUMETHIAZIDE On 2 Cardiovascular system->2.2 Diuretics->2.2.1 Thiazides and related diuretics METOLAZONE On 2 Cardiovascular system->2.2 Diuretics->2.2.1 Thiazides and related diuretics INDAPAMIDE Restricted 2 Cardiovascular system->2.2 Diuretics->2.2.1 Thiazides and related diuretics->bendroflumethiazide Bendroflumethiazide On 2 Cardiovascular system->2.2 Diuretics->2.2.1 Thiazides and related diuretics->indapamide Indapamide Restricted 2 Cardiovascular system->2.2 Diuretics->2.2.1 Thiazides and related diuretics->indapamide Modified release Restricted 2 Cardiovascular system->2.2 Diuretics->2.2.1 Thiazides and related diuretics->indapamide->modified release Natrilix SR Restricted

7 2 Cardiovascular system->2.2 Diuretics->2.2.2 Loop diuretics BUMETANIDE On 2 Cardiovascular system->2.2 Diuretics->2.2.2 Loop diuretics FUROSEMIDE On 2 Cardiovascular system->2.2 Diuretics->2.2.2 Loop diuretics- >BUMETANIDE Bumetanide On 2 Cardiovascular system->2.2 Diuretics->2.2.2 Loop diuretics- >FUROSEMIDE Furosemide On 2 Cardiovascular system->2.2 Diuretics->2.2.3 Potassium-sparing diuretics and aldosterone antagonists AMILORIDE HYDROCHLORIDE On 2 Cardiovascular system->2.2 Diuretics->2.2.3 Potassium-sparing diuretics and aldosterone antagonists->aldosterone antagonists SPIRONOLACTONE On 2 Cardiovascular system->2.2 Diuretics->2.2.3 Potassium-sparing diuretics and aldosterone antagonists->aldosterone antagonists EPLERENONE Restricted 2 Cardiovascular system->2.2 Diuretics->2.2.3 Potassium-sparing diuretics and aldosterone antagonists->aldosterone antagonists- >SPIRONOLACTONE Spironolactone On 2 Cardiovascular system->2.2 Diuretics->2.2.3 Potassium-sparing diuretics and aldosterone antagonists->amiloride HYDROCHLORIDE Amiloride On 2 Cardiovascular system->2.2 Diuretics->2.2.4 Potassium-sparing diuretics with other diuretics CO-AMILOFRUSE On 2 Cardiovascular system->2.2 Diuretics->2.2.5 Osmotic diuretics MANNITOL Restricted 2 Cardiovascular system->2.2 Diuretics->2.2.5 Osmotic diuretics- >MANNITOL Mannitol Restricted 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->supraventricular and ventricular arrhythmias AMIODARONE HYDROCHLORIDE On 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->supraventricular and ventricular arrhythmias FLECAINIDE ACETATE Restricted 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->supraventricular and ventricular arrhythmias PROPAFENONE HYDROCHLORIDE Restricted 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->supraventricular and ventricular arrhythmias- >AMIODARONE HYDROCHLORIDE Amiodarone On 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->supraventricular and ventricular arrhythmias- >FLECAINIDE ACETATE Flecainide Restricted 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->supraventricular arrhythmias ADENOSINE On 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->supraventricular arrhythmias->adenosine Adenocor Restricted 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->ventricular arrhythmias LIDOCAINE HYDROCHLORIDE On 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->ventricular arrhythmias->lidocaine HYDROCHLORIDE Lidocaine On 2 Cardiovascular system->2.3 Anti-arrhythmic drugs->2.3.2 Drugs for arrhythmias->ventricular arrhythmias->lidocaine HYDROCHLORIDE Minijet Lignocaine On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs ATENOLOL On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs BISOPROLOL FUMARATE On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs LABETALOL HYDROCHLORIDE On

8 Section 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs METOPROLOL TARTRATE On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs PROPRANOLOL HYDROCHLORIDE On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs CARVEDILOL Restricted 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs ESMOLOL HYDROCHLORIDE Restricted 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs SOTALOL HYDROCHLORIDE Restricted 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >ATENOLOL Atenolol On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >BISOPROLOL FUMARATE Bisoprolol Fumarate On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >CARVEDILOL Carvedilol Restricted 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >ESMOLOL HYDROCHLORIDE Brevibloc Restricted 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >LABETALOL HYDROCHLORIDE Labetalol Hydrochloride On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >METOPROLOL TARTRATE Metoprolol Tartrate On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >PROPRANOLOL HYDROCHLORIDE Propranolol On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >PROPRANOLOL HYDROCHLORIDE->Modified release Half-Inderal LA On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >PROPRANOLOL HYDROCHLORIDE->Modified release Inderal-LA On 2 Cardiovascular system->2.4 Beta-adrenoceptor blocking drugs- >SOTALOL HYDROCHLORIDE Sotalol Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs HYDRALAZINE HYDROCHLORIDE On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs DIAZOXIDE Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs ILOPROST Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs MINOXIDIL Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs SODIUM NITROPRUSSIDE Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs->diazoxide Eudemine Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs->hydralazine HYDROCHLORIDE Hydralazine On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs->iloprost Ventavis Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs->minoxidil Loniten Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.1 Vasodilator antihypertensive drugs->sodium NITROPRUSSIDE Sodium Nitroprusside Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.2 Centrally acting antihypertensive drugs CLONIDINE HYDROCHLORIDE On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.2 Centrally acting antihypertensive drugs METHYLDOPA On

9 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.2 Centrally acting antihypertensive drugs MOXONIDINE Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.2 Centrally acting antihypertensive drugs->clonidine HYDROCHLORIDE Catapres On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.2 Centrally acting antihypertensive drugs->methyldopa Methyldopa On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.2 Centrally acting antihypertensive drugs->moxonidine Moxonidine Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.3 Adrenergic neurone blocking drugs GUANETHIDINE MONOSULFATE Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.4 Alpha-adrenoceptor blocking drugs DOXAZOSIN On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.4 Alpha-adrenoceptor blocking drugs->doxazosin Doxazosin On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensinconverting enzyme inhibitors LISINOPRIL On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensinconverting enzyme inhibitors PERINDOPRIL ERBUMINE On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensinconverting enzyme inhibitors RAMIPRIL On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensinconverting enzyme inhibitors CAPTOPRIL Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensinconverting enzyme inhibitors->captopril Captopril Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensinconverting enzyme inhibitors->lisinopril Lisinopril On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensinconverting enzyme inhibitors->ramipril Ramipril On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensin-II receptor antagonists LOSARTAN POTASSIUM On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensin-II receptor antagonists CANDESARTAN CILEXETIL Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensin-II receptor antagonists IRBESARTAN Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensin-II receptor antagonists->candesartan CILEXETIL Amias On 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensin-II receptor antagonists->irbesartan Aprovel Restricted 2 Cardiovascular system->2.5 Hypertension and heart failure->2.5.5 Drugs affecting the renin-angiotensin system-> Angiotensin-II receptor antagonists->losartan POTASSIUM Cozaar Restricted

10 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates GLYCERYL TRINITRATE On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates ISOSORBIDE DINITRATE On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates ISOSORBIDE MONONITRATE On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates->GLYCERYL TRINITRATE Parenteral preparations Restricted 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates->GLYCERYL TRINITRATE- >Short-acting tablets and sprays Glyceryl Trinitrate On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates->GLYCERYL TRINITRATE- >Transdermal preparations Deponit On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates->ISOSORBIDE DINITRATE->Modified-release preparations Isoket Retard On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates->ISOSORBIDE DINITRATE->Short-acting tablets and sprays Isosorbide Dinitrate On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates->ISOSORBIDE MONONITRATE Isosorbide Mononitrate On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.1 Nitrates->ISOSORBIDE MONONITRATE Modified release On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers AMLODIPINE On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers DILTIAZEM HYDROCHLORIDE On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers NIFEDIPINE On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers VERAPAMIL HYDROCHLORIDE On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers NIMODIPINE Restricted 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >AMLODIPINE Amlodipine On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >DILTIAZEM HYDROCHLORIDE Longer-acting formulations On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >DILTIAZEM HYDROCHLORIDE->Standard formulations Tildiem On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >NIFEDIPINE Modified release On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >NIFEDIPINE Nifedipine On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >NIFEDIPINE->Modified release Adalat LA On

11 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >NIFEDIPINE->Modified release Adalat Retard On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >NIMODIPINE Nimotop Restricted 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >VERAPAMIL HYDROCHLORIDE Modified release On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.2 Calcium-channel blockers- >VERAPAMIL HYDROCHLORIDE Verapamil On 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.3 Other antianginal drugs IVABRADINE NICE-approved 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.3 Other antianginal drugs NICORANDIL Restricted 2 Cardiovascular system->2.6 Nitrates, calcium-channel blockers, and other antianginal drugs->2.6.4 Peripheral vasodilators and related drugs NAFTIDROFURYL OXALATE NICE-approved 2 Cardiovascular system->2.7 Sympathomimetics->2.7.1 Inotropic sympathomimetics DOBUTAMINE Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.1 Inotropic sympathomimetics DOPAMINE HYDROCHLORIDE Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.1 Inotropic sympathomimetics->dobutamine Dobutamine Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.1 Inotropic sympathomimetics->dopamine HYDROCHLORIDE Dopamine Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.2 Vasoconstrictor sympathomimetics METARAMINOL Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.2 Vasoconstrictor sympathomimetics 2 Cardiovascular system->2.7 Sympathomimetics->2.7.2 Vasoconstrictor sympathomimetics NORADRENALINE/NOREPINEPHRI NE PHENYLEPHRINE HYDROCHLORIDE Restricted Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.2 Vasoconstrictor sympathomimetics->metaraminol Metaraminol Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.2 Vasoconstrictor sympathomimetics- >NORADRENALINE/NOREPINEPHRINE Noradrenaline/Norepinephrine Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.2 Vasoconstrictor sympathomimetics->phenylephrine HYDROCHLORIDE Phenylephrine Restricted 2 Cardiovascular system->2.7 Sympathomimetics->2.7.3 Cardiopulmonary resuscitation ADRENALINE/EPINEPHRINE On 2 Cardiovascular system->2.7 Sympathomimetics->2.7.3 Cardiopulmonary resuscitation->adrenaline/epinephrine Adrenaline/Epinephrine 1 in 10?000, Dilute On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants Heparin On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants Heparin flushes On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants Low molecular weight heparins On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants Epoprostenol Restricted

12 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants Heparinoids Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants Hirudins Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->epoprostenol EPOPROSTENOL Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->epoprostenol->epoprostenol Flolan Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->heparin HEPARIN On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->heparin flushes Heparin Sodium On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->heparinoids DANAPAROID SODIUM Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->heparinoids->danaparoid SODIUM Orgaran Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->hirudins BIVALIRUDIN Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->hirudins->bivalirudin Angiox Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.1 Parenteral anticoagulants->low molecular weight heparins ENOXAPARIN SODIUM On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->apixaban APIXABAN NICE-approved 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->apixaban APIXABAN NICE-approved 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->coumarins and phenindione WARFARIN SODIUM On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->coumarins and phenindione ACENOCOUMAROL Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->coumarins and phenindione PHENINDIONE Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->coumarins and phenindione->phenindione Phenindione Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->coumarins and phenindione->warfarin SODIUM Warfarin On 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->dabigatran etexilate DABIGATRAN ETEXILATE NICE-approved 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->dabigatran etexilate DABIGATRAN ETEXILATE NICE-approved 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->rivaroxaban RIVAROXABAN Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->rivaroxaban RIVAROXABAN Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->rivaroxaban RIVAROXABAN Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.2 Oral anticoagulants->rivaroxaban RIVAROXABAN Restricted 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.3 Protamine sulfate PROTAMINE SULFATE Restricted

13 2 Cardiovascular system->2.8 Anticoagulants and protamine->2.8.3 Protamine sulfate->protamine SULFATE Protamine Sulfate Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs ASPIRIN (antiplatelet) On 2 Cardiovascular system->2.9 Antiplatelet drugs ABCIXIMAB Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs CLOPIDOGREL Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs DIPYRIDAMOLE Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs PRASUGREL Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs TICAGRELOR Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs TIROFIBAN Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs->aspirin (antiplatelet) Aspirin On 2 Cardiovascular system->2.9 Antiplatelet drugs->dipyridamole Dipyridamole Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs->dipyridamole Modified release Restricted 2 Cardiovascular system->2.9 Antiplatelet drugs->dipyridamole- >Modified release Persantin Retard Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Selective beta2 agonists SALBUTAMOL On 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Selective beta2 agonists SALMETEROL On 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Selective beta2 agonists TERBUTALINE SULFATE Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Selective beta2 agonists->salbutamol- >Inhalation Salbutamol On 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Selective beta2 agonists->salbutamol->oral Salbutamol Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Selective beta2 agonists->salbutamol- >Parenteral Ventolin On 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Selective beta2 agonists->terbutaline SULFATE Inhalation Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Selective beta2 agonists->terbutaline SULFATE Oral and parenteral Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.1 Adrenoceptor agonists-> Other adrenoceptor agonists EPHEDRINE HYDROCHLORIDE Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.2 Antimuscarinic bronchodilators IPRATROPIUM BROMIDE On 3 Respiratory system->3.1 Bronchodilators->3.1.2 Antimuscarinic bronchodilators GLYCOPYRRONIUM Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.2 Antimuscarinic bronchodilators TIOTROPIUM Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.2 Antimuscarinic bronchodilators->ipratropium BROMIDE Atrovent On 3 Respiratory system->3.1 Bronchodilators->3.1.2 Antimuscarinic bronchodilators->ipratropium BROMIDE Ipratropium Bromide On 3 Respiratory system->3.1 Bronchodilators->3.1.3 Theophylline AMINOPHYLLINE Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.3 Theophylline THEOPHYLLINE Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.3 Theophylline- >AMINOPHYLLINE Aminophylline Restricted

14 3 Respiratory system->3.1 Bronchodilators->3.1.3 Theophylline- >AMINOPHYLLINE Modified release Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.3 Theophylline- >AMINOPHYLLINE->Modified release Phyllocontin Continus Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.3 Theophylline- >THEOPHYLLINE Modified release Restricted 3 Respiratory system->3.1 Bronchodilators->3.1.5 Peak flow meters, inhaler devices and nebulisers->drug delivery devices Able Spacer On 3 Respiratory system->3.1 Bronchodilators->3.1.5 Peak flow meters, inhaler devices and nebulisers->drug delivery devices AeroChamber Plus On 3 Respiratory system->3.1 Bronchodilators->3.1.5 Peak flow meters, inhaler devices and nebulisers->drug delivery devices Haleraid On 3 Respiratory system->3.1 Bronchodilators->3.1.5 Peak flow meters, inhaler devices and nebulisers->drug delivery devices Volumatic On 3 Respiratory system->3.1 Bronchodilators->3.1.5 Peak flow meters, inhaler devices and nebulisers->nebuliser diluent Sodium Chloride On 3 Respiratory system->3.1 Bronchodilators->3.1.5 Peak flow meters, inhaler devices and nebulisers->peak flow meters Low Range Peak Flow Meter On 3 Respiratory system->3.1 Bronchodilators->3.1.5 Peak flow meters, inhaler devices and nebulisers->peak flow meters Standard Range Peak Flow Meter On 3 Respiratory system->3.11 Antifibrotics PIRFENIDONE NICE-approved 3 Respiratory system->3.2 Corticosteroids BECLOMETASONE DIPROPIONATE On 3 Respiratory system->3.2 Corticosteroids BUDESONIDE Restricted 3 Respiratory system->3.2 Corticosteroids->BECLOMETASONE DIPROPIONATE Beclometasone On 3 Respiratory system->3.2 Corticosteroids->BECLOMETASONE DIPROPIONATE Clenil Modulite On 3 Respiratory system->3.2 Corticosteroids->BECLOMETASONE DIPROPIONATE->Compound preparations Fostair On 3 Respiratory system->3.2 Corticosteroids->BUDESONIDE Budesonide Restricted 3 Respiratory system->3.2 Corticosteroids->BUDESONIDE Pulmicort Restricted 3 Respiratory system->3.2 Corticosteroids->BUDESONIDE- >Compound preparations Symbicort Restricted 3 Respiratory system->3.2 Corticosteroids->FLUTICASONE PROPIONATE->Compound preparations Seretide Restricted 3 Respiratory system->3.3 Cromoglicate and related therapy, leukotriene receptor antagonists, and phosphodiesterase type-4 inhibitors->3.3.2 Leukotriene receptor antagonists MONTELUKAST Restricted 3 Respiratory system->3.3 Cromoglicate and related therapy, leukotriene receptor antagonists, and phosphodiesterase type-4 inhibitors->3.3.3 Phosphodiesterase type-4 inhibitors ROFLUMILAST NICE-approved 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.1 Antihistamines->Non-sedating antihistamines CETIRIZINE HYDROCHLORIDE On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.1 Antihistamines->Non-sedating antihistamines LORATADINE On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.1 Antihistamines->Non-sedating antihistamines->cetirizine HYDROCHLORIDE Cetirizine On

15 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.1 Antihistamines->Non-sedating antihistamines->loratadine Loratadine On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.1 Antihistamines->Sedating antihistamines CHLORPHENAMINE MALEATE On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.1 Antihistamines->Sedating antihistamines HYDROXYZINE HYDROCHLORIDE On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.1 Antihistamines->Sedating antihistamines PROMETHAZINE HYDROCHLORIDE On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.1 Antihistamines->Sedating antihistamines->chlorphenamine MALEATE Chlorphenamine On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.2 Allergen immunotherapy 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.2 Allergen immunotherapy BEE AND WASP ALLERGEN EXTRACTS GRASS AND TREE POLLEN EXTRACTS On On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.2 Allergen immunotherapy->bee AND WASP ALLERGEN EXTRACTS Pharmalgen NICE-approved 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.2 Allergen immunotherapy->grass AND TREE POLLEN EXTRACTS Grass pollen extract Restricted 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.2 Allergen immunotherapy->grass AND TREE POLLEN EXTRACTS->Grass pollen extract Grazax Restricted 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.2 Allergen immunotherapy->omalizumab OMALIZUMAB NICE-approved 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.3 Allergic emergencies->anaphylaxis ADRENALINE/EPINEPHRINE On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.3 Allergic emergencies->anaphylaxis- >ADRENALINE/EPINEPHRINE->Intramuscular or subcutaneous Adrenaline/Epinephrine 1 in 1000 On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.3 Allergic emergencies->anaphylaxis- >ADRENALINE/EPINEPHRINE->Intramuscular or subcutaneous Minijet Adrenaline 1 in 1000 On 3 Respiratory system->3.4 Antihistamines, hyposensitisation, and allergic emergencies->3.4.3 Allergic emergencies->angioedema C1-ESTERASE INHIBITOR Restricted 3 Respiratory system->3.5 Respiratory stimulants and pulmonary surfactants->3.5.1 Respiratory stimulants DOXAPRAM HYDROCHLORIDE Restricted 3 Respiratory system->3.5 Respiratory stimulants and pulmonary surfactants->3.5.1 Respiratory stimulants->doxapram HYDROCHLORIDE Dopram Restricted 3 Respiratory system->3.5 Respiratory stimulants and pulmonary surfactants->3.5.2 Pulmonary surfactants PORACTANT ALFA Restricted 3 Respiratory system->3.7 Mucolytics CARBOCISTEINE Restricted

16 3 Respiratory system->3.7 Mucolytics Dornase alfa Restricted 3 Respiratory system->3.7 Mucolytics->CARBOCISTEINE Carbocisteine Restricted 3 Respiratory system->3.7 Mucolytics->Dornase alfa DORNASE ALFA Restricted 3 Respiratory system->3.7 Mucolytics->Mannitol MANNITOL NICE-approved 3 Respiratory system->3.8 Aromatic inhalations Benzoin Tincture, Compound, BP On 3 Respiratory system->3.9 Cough preparations->3.9.1 Cough suppressants PHOLCODINE On 3 Respiratory system->3.9 Cough preparations->3.9.1 Cough suppressants CODEINE PHOSPHATE Restricted 3 Respiratory system->3.9 Cough preparations->3.9.1 Cough suppressants->codeine PHOSPHATE Codeine Linctus, BP On 3 Respiratory system->3.9 Cough preparations->3.9.1 Cough suppressants->palliative care MORPHINE HYDROCHLORIDE On 3 Respiratory system->3.9 Cough preparations->3.9.1 Cough suppressants->palliative care METHADONE HYDROCHLORIDE Restricted 3 Respiratory system->3.9 Cough preparations->3.9.1 Cough suppressants->pholcodine Pholcodine Linctus, BP On 3 Respiratory system->3.9 Cough preparations->3.9.2 Demulcent and expectorant cough preparations Simple Linctus, BP On 3 Respiratory system->3.9 Cough preparations->3.9.2 Demulcent and expectorant cough preparations Simple Linctus, Paediatric, BP On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.1 Hypnotics->Antihistamines PROMETHAZINE HYDROCHLORIDE On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.1 Hypnotics->Benzodiazepines TEMAZEPAM On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.1 Hypnotics->Benzodiazepines->TEMAZEPAM Temazepam On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.1 Hypnotics->Chloral and derivatives CHLORAL HYDRATE Restricted 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.1 Hypnotics->Chloral and derivatives->chloral HYDRATE Chloral Mixture, BP 2000 Restricted 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.1 Hypnotics->Zaleplon, zolpidem, and zopiclone ZOPICLONE On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.1 Hypnotics->Zaleplon, zolpidem, and zopiclone->zopiclone Zopiclone On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.2 Anxiolytics->Benzodiazepines DIAZEPAM On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.2 Anxiolytics->Benzodiazepines LORAZEPAM On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.2 Anxiolytics->Benzodiazepines->DIAZEPAM Diazepam On 4 Central nervous system->4.1 Hypnotics and anxiolytics->4.1.2 Anxiolytics->Benzodiazepines->LORAZEPAM Lorazepam On 4 Central nervous system->4.10 Drugs used in substance dependence-> Alcohol dependence->acamprosate ACAMPROSATE CALCIUM Restricted 4 Central nervous system->4.10 Drugs used in substance dependence-> Nicotine dependence->bupropion BUPROPION HYDROCHLORIDE On 4 Central nervous system->4.10 Drugs used in substance dependence-> Nicotine dependence->nicotine replacement therapy NICOTINE On

17 4 Central nervous system->4.10 Drugs used in substance dependence-> Nicotine dependence->nicotine replacement therapy->nicotine NiQuitin On 4 Central nervous system->4.10 Drugs used in substance dependence-> Nicotine dependence->varenicline VARENICLINE Restricted 4 Central nervous system->4.10 Drugs used in substance dependence-> Opioid dependence->opioid substitution therapy BUPRENORPHINE Restricted 4 Central nervous system->4.10 Drugs used in substance dependence-> Opioid dependence->opioid substitution therapy METHADONE HYDROCHLORIDE Restricted 4 Central nervous system->4.10 Drugs used in substance dependence-> Opioid dependence->opioid substitution therapy->methadone HYDROCHLORIDE Methadone Restricted 4 Central nervous system->4.10 Drugs used in substance dependence-> Opioid dependence->opioid-receptor antagonists NALTREXONE HYDROCHLORIDE NICE-approved 4 Central nervous system->4.11 Drugs for dementia GALANTAMINE NICE-approved 4 Central nervous system->4.11 Drugs for dementia MEMANTINE HYDROCHLORIDE NICE-approved 4 Central nervous system->4.11 Drugs for dementia RIVASTIGMINE NICE-approved 4 Central nervous system->4.11 Drugs for dementia DONEPEZIL HYDROCHLORIDE Restricted 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs CHLORPROMAZINE HYDROCHLORIDE On 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs HALOPERIDOL On 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs PROCHLORPERAZINE On 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs PROMAZINE HYDROCHLORIDE On 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs TRIFLUOPERAZINE On 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs FLUPENTIXOL Restricted 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs LEVOMEPROMAZINE Restricted 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs->chlorpromazine HYDROCHLORIDE Chlorpromazine On 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs->haloperidol Haloperidol On 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs->promazine HYDROCHLORIDE Promazine On 4 Central nervous system->4.2 Drugs used in psychoses and related disorders->4.2.1 Antipsychotic drugs->first-generation antipsychotic drugs->trifluoperazine Trifluoperazine On