Pharmacology for the Health Care Professions
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1 Pharmacology for the Health Care Professions Christine M. Thorp University of Salford, UK )WILEY-BLACKWELL A John Wiley & Sons, Ltd., Publication
2 Contents Foreword Preface Acknowledgements xüi xv xvii 1 Introduction Pharmacology and health care Professionals Patient compliance Drag names 4 Part I Principles of pharmacology 7 Drug disposition Chapter overview Administration of drugs Absorption of drugs Drug distribution Drug metabolism Excretion of drugs Summary Effects of drugs on the body Chapter overview Adverse reactions to drugs Variation in response to drug therapy Targets for drug action Summary Part II Systemic pharmacology 49 4 Cardiovascular and blood disorders Cardiovascular disorders 51
3 viü CONTENTS 4.2 Hypertension Drugs used to treat cardiovascular disorders Blood disorders Anaemias Lipid metabolism Lipid-lowering drugs Summary 79 5 Respiratory Disorders Chapter overview Asthma Chronic bronchitis Drugs used to treat respiratory disorders Treatment of other respiratory conditions Summary 94 6 Disorders of the endocrine System Chapter overview Pituitary gland Thyroid gland Parathyroid glands Adrenal glands Pancreas Treatment of diabetes mellites Summary Disorders of the musculoskeletal System Chapter overview Rheumatic diseases Drugs used to treat rheumatic diseases Gout Drugs used to treat gout Osteoarthritis Paget's disease Treatment of Paget's disease Osteoporosis Drugs used to treat osteoporosis Osteomalacia Myasthenia gravis Treatment of myasthenia gravis Motor neuron disease and multiple sclerosis Summary 132
4 CONTENTS ix 8 Disorders of the skin Chapter overview Eczema Treatment of eczema Psoriasis Treatment of psoriasis Warts Treatment of warts Other viral infections of the skin Fungal infections of the skin and nails Drugs used to treat fungal infection of the skin and nails Bacterial infection of the skin Summary Chemotherapy of infectious diseases Chapter overview Bacteria Antibiotic drugs Treatment of tuberculosis Viruses Antiviral drugs Treatment of HIV infection Fungi Antifungal drugs Protozoa Antimalarial drugs Drugs for toxoplasma and pneumocystis pneumonia Parasitic worms Anthelmintics Summary Cancer chemotherapy Chapter overview Biology of cancer Principles of chemotherapy Drugs used in cancer chemotherapy Summary Disorders of the central nervous System Chapter overview Affective disorders Drugs used to treat depression 198
5 x CONTENTS 11.4 Drugs used to treat bipolar depression and mania Psychoses Drugs used to treat schizophrenia Anxiety and insomnia Anxiolytics and hypnotics Treatment of anxiety Treatment of insomnia Attention deficit hyperactivity disorder (ADHD) Treatment of ADHD Parkinson' s disease Drugs used to treat Parkinson' s disease Epilepsy Drugs used to treat epilepsy Alzheimer's disease Treatment of Alzheimer' s disease Summary Anaesthesia and analgesia Chapter overview General anaesthesia Inhalation anaesthetics Intravenous anaesthetics Premedication and adjuncts to general anaesthesia Local anaesthesia Local anaesthetics Analgesia Peripherally acting analgesics Centrally acting analgesics Neuropathie pain Summary Contrast agents and adjuncts to radiography Chapter overview Contrast agents Cautions in use of contrast agents Complications of intravenous administration of contrast agents Adverse reactions to contrast agents Management of acute adverse reactions to contrast agents Adjuncts to radiography Summary 264
6 CONTENTS xi Part III Prescribing and the law Medicines, the law and health care Professionals Chapter overview Legislation Non-medical prescribing Summary Prescribing in practice Chapter overview Podiatry Extension of access to prescription-only medicines in podiatry and podiatic surgery Podiatry in the Community Radiography Medicines in radiography: prescription, supply and administration Physiotherapy Summary 319 Appendices 321 Appendix A: Drug Names 323 Appendix B: Glossary 331 Appendix C: Examples of Patient Group Directions 337 Bibliography 343 Useful Websites 345 Index 349
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