Axon Guidance. Matthew Blewitt
|
|
- Meghan Crawford
- 6 years ago
- Views:
Transcription
1 Axon Guidance Matthew Blewitt
2 Overview Axonal development PNS regeneration CNS regeneration Future directions Brain Repair
3 Axonal Development Neurite growth cone
4 Growth Cone Interactions Target Cell Molecular guidance cues Netrin, slit, semaphorins, ephrins Trophic factors Adjacent Cells NCAMs, cadherins Extracellular Matrix Laminin, collagen, fibronectin
5 Synapse Formation Gradual process Receptor rearrangement May use the some of the same adhesion molecules as guidance
6 Peripheral Nerve Damage More than 200,000 procedures/year Limited regeneration Schwann cells provide guidance and support
7 Gap limitations Target acquisition Peripheral Nerve Injury
8 Peripheral Nerve Repair Nerve repair is fairly successful but can have detrimental side effects Most current treatments do not provide complete recovery Gaps over 1cm require bridge Nerve autograft Autoveingraft < 3cm gap images/
9 Spinal Cord Injury 12,000-15,000 traumatic spinal cord injuries/year US\ ~10,000 of which are permantly paralyzed Young healthy individuals age Motor vehicle accidents 44.5% Falls (45 and older) 18.1% Violence 16.6% Sports (diving) 12.7%
10 CNS Injury
11 CNS Injury What is the difference between CNS and PNS injury? Schwann cells versus oligodendrocytes and astrocytes No gene expression Formation of retraction neuroma Growth inhibiting molecules Microglia, macrophage, astrocytes and glial scar
12 Inhibiting Molecules Oligodendrocyte and myelin associated proteins Nogo and myelin associated glycoprotein (MAG) IN-1 antibody successful Proteoglycans found in the glial scar
13 Spinal Cord Treatment Steroids to reduce swelling that may help take stress off of axons Surgery to remove tissue or fluid pressure Bed rest and traction to reset anatomic position Rehabilitation All of these are to alleviate excess stress on axons but do not heal damage
14 Current Research Neural guidance conduits Biological Vein grafting Conduit filled with predegenerated skeletal muscle Decellularized nerve grafts Collagen nerve tubes Synthetic Polymer based Necessary adhesion molecules must be crosslinked
15 CNS Specific Research Antibodies to growth inhibiting factors Electrical stimulation DRGs stimulated but not guided Peripheral nerve and Schwann implantation PNS will not grow into CNS Fetal tissue transplants Olfactory glial cells May work better than Schwann because enter CNS Genetic modification
16 Future Outlook More inhibiting molecules need to be identified to be able to produce more antibodies Combined treatments will probably be necessary Immunosuppressant and biocompatibility assessment
17 A note on Brain Damage Complex issue on its own There is adult neurogenesis in olfactory bulbs and hippocampus Antidepressants have been shown to stimulate neurogenesis
18 References technologies/projects/nerve_regen.html images/ D. Purves, Neuroscience 3 rd Ed. Sinuaer Associated, Inc. Sutherland, Ma. (2004) K. Kalil, G. Szebenyi, E. W. Dent, Journal of Neurobiology 44, 145 (2000). J. Lu, P. Waite, Spine 24, 926 (May 1, 1999). B. J. Dickson, Science 298, 1959 (Dec 6, 2002). B. P. Liu, A. Fournier, T. GrandPre, S. M. Strittmatter, Science 297, 1190 (Aug 16, 2002). D. Hunt, R. S. Coffin, P. N. Anderson, Journal of Neurocytology 31, 93 (Feb, 2002). F. H. Gage, Scientific American 289, 46 (Sep, 2003). L.S. Rummler, R. Gupta, Current Opinion in Orthopaedics 15, 215 (2004)
Symptoms of spinal cord injury:
Symptoms of spinal cord injury: involuntary muscle spasms loss of voluntary movement sensation, balance control of breathing autonomic functions (blood pressure) bladder, sexual, bowel control All due
More informationAdult Nervous System
Adult Nervous System What is the capacity of the PNS and CNS for repair? WHY? Why discuss this now? Potential for repair depends on cellular properties of nerve and glial cells. http://neuroscience.uth.tmc.edu/s1/chapter09.html
More informationBrain Development III
Brain Development III Neural Development In the developing nervous system there must be: 1. The formation of different regions of the brain. 2. The ability of a neuron to differentiate. 3. The ability
More informationReaction to Injury & Regeneration. Steven McLoon Department of Neuroscience University of Minnesota
Reaction to Injury & Regeneration Steven McLoon Department of Neuroscience University of Minnesota 1 Course News Dec 4 (Mon) Dec 6 (Wed) adult neurogenesis injury & regeneration Dec 8 (Fri) research paper
More informationervous system: central nervous system (CNS) and eripheral nervous system (PNS) NS includes the brain and spinal cord NS consists of the cranial
Physiology of the peripheral nervous system ervous system: central nervous system (CNS) and eripheral nervous system (PNS) NS includes the brain and spinal cord NS consists of the cranial nerves from brain
More informationApril 29, Neurophysiology. Chul-Kyu Park, Ph.D. Assistant Professor Department of Physiology, Graduate School of Medicine, Gachon University,
April 29, 2016 Neurophysiology Chul-Kyu Park, Ph.D. Assistant Professor Department of Physiology, Graduate School of Medicine, Gachon University, Cells in the brain Neurons glia 1. Astrocytes 2. Microglia
More informationNew Approaches to Repair of Spinal Cord Injury
New Approaches to Repair of Spinal Cord Injury 1 WHY IS THE SPINAL CORD SO VULNERABLE? Peripheral Nerve Spinal Cord Schwann Cell Myelin DRG Neuron Oligodendrocyte Myelin Collagen Axon 2 3 WHY IS THE SPINAL
More informationregenerative medicine in the brain and the spinal cord spinal cord injuries
regenerative medicine in the brain and the spinal cord spinal cord injuries primary and secondary events during SCI traumatic spinal cord injury (SCI) traumatic spinal cord injury (SCI) main goal is to
More informationNervous Tissue Mediates Perception and Response *
OpenStax-CNX module: m46057 1 Nervous Tissue Mediates Perception and Response * OpenStax This work is produced by OpenStax-CNX and licensed under the Creative Commons Attribution License 3.0 By the end
More informationOlfactory ensheathing glia
Olfactory ensheathing glia From Wikipedia, the free encyclopedia Neuroglia of the brain shown by Golgi's method. Olfactory ensheathing glia (OEG), also known as olfactory ensheathing cells (OECs) or olfactory
More informationCells of the nervous system
Neurobiology Cells of the nervous system Anthony Heape 2011 1 Cells of the nervous system Neuroglia : part 2 The non excitable cells of the nervous system that provide support to neuronal survival and
More informationBIOL241 - Lecture 12a
Cranial Nerves, source: training.seer.cancer.gov Nervous System Overview BIOL241 - Lecture 12a 1 Topics Divisions of the NS: CNS and PNS Structure and types of neurons Synapses Structure and function of
More informationMan and his environment
Man and his environment Dr. Elriah M. Makie 0122858517 Nervous Tissue BSc.M.Sc.MBBS Introduction The nervous system is divided into two main parts: The central nervous system (CNS) comprising the brain
More informationHuman Histology The Nervous System. Dr. Rawaa Salim Hameed
Human Histology The Nervous System Dr. Rawaa Salim Hameed The organization of the nervous system Anatomically, the nervous system is divided into:- Neurohistology Structurally, nerve tissue consists of
More informationMeyers' A&P February 15, Unit 7. The Nervous System. I. Functions of the Nervous System. Monitors body's internal and external enviornments
Unit 7 The Nervous System I. Functions of the Nervous System Monitors body's internal and external enviornments Integrates sensory information Coordinates voluntary & involuntary responses of many other
More informationFunctions of Nervous System Neuron Structure
Chapter 10 Nervous System I Divisions of the Nervous System Cell Types of Neural Tissue neurons neuroglial cells Central Nervous System brain spinal cord Peripheral Nervous System nerves cranial nerves
More informationPrinciples of Anatomy and Physiology
Principles of Anatomy and Physiology 14 th Edition CHAPTER 12 Nervous Tissue Introduction The purpose of the chapter is to: 1. Understand how the nervous system helps to keep controlled conditions within
More informationThe Nervous System: Neural Tissue
C h a p t e r 13 The Nervous System: Neural Tissue PowerPoint Lecture Slides prepared by Jason LaPres North Harris College Houston, Texas Copyright 2009 Pearson Education, Inc., publishing as Pearson Benjamin
More informationLecture 3 (Oct 5 th ): NEURONS AND NERVE IMPULSES Lecture Outline
Lecture 3 (Oct 5 th ): NEURONS AND NERVE IMPULSES Lecture Outline 1) CNS vs. PNS 2) Structure of Neurons parts of a neuron: soma, dendrites, axons 3) Glial Cells 4) Mitosis and Regeneration in Neurons
More informationSpinal cord injury (SCI) throughout history
Overview of Cellular Therapies in Spinal Cord Injuries Jesse OWENS Biomedical Program, University of Alaska, Anchorage, Alaska Spinal cord injury (SCI) throughout history has been considered untreatable.
More informationNervous System. Master controlling and communicating system of the body. Secrete chemicals called neurotransmitters
Nervous System Master controlling and communicating system of the body Interacts with the endocrine system to control and coordinate the body s responses to changes in its environment, as well as growth,
More informationNerve tissue & the Nervous System
Nerve tissue & the Nervous System The human nervous system, by far the most complex system in the body, is formed by a network of many billion nerve cells (neurons), all assisted by many more supporting
More informationChapter 7. The Nervous System
Chapter 7 The Nervous System General overview of the nervous system functions Sensory input (info travels in along afferent pathways) Integration (information is processed) Sensory neurons Spinal cord
More informationInner ear development Nervous system development
Upcoming Sessions April 22: Nervous System Development Lecture April 24: Reviews of Axonal Pathfinding in Sensory Systems April 29: Inner Ear Development Lecture May 1: May 6: May 8: Auditory System Pathfinding
More informationAnatomy of a Neuron. Copyright 2000 by BSCS and Videodiscovery, Inc. Permission granted for classroom use. Updated Master 2.
Anatomy of a Neuron Master 2.1 Neurons Interact with Other Neurons through Synapses Master 2.2 Name Date Due Cells of the Nervous System Learning Target: Identify and state the function of the components
More informationThe Nervous System: Neural Tissue Pearson Education, Inc.
13 The Nervous System: Neural Tissue Introduction Nervous System Characteristics Controls and adjust the activity of the body Provides swift but brief responses The nervous system includes: Central Nervous
More information! BIOL 2401! Week 5. Nervous System. Nervous System
Collin County Community College! BIOL 2401! Week 5 Nervous System 1 Nervous System The process of homeostasis makes sure that the activities that occur in the body are maintained within normal physiological
More informationOutline. Animals: Nervous system. Neuron and connection of neurons. Key Concepts:
Animals: Nervous system Neuron and connection of neurons Outline 1. Key concepts 2. An Overview and Evolution 3. Human Nervous System 4. The Neurons 5. The Electrical Signals 6. Communication between Neurons
More informationBrain Plasticity. Brain Plasticity. Recovery from Deprivation 1/2/11. Dogma. Modern neuroscience. Deprivation can lower IQ. Deprivation reversed
Brain Plasticity Brain Plasticity Dogma Adult brain is stable, unchanging Lose neurons Do not grow/repair neurons Modern neuroscience Brain changes throughout life plasticity Extra capacity Face life s
More informationMajor Structures of the Nervous System. Brain, cranial nerves, spinal cord, spinal nerves, ganglia, enteric plexuses and sensory receptors
Major Structures of the Nervous System Brain, cranial nerves, spinal cord, spinal nerves, ganglia, enteric plexuses and sensory receptors Nervous System Divisions Central Nervous System (CNS) consists
More informationHuman Anatomy and Physiology - Problem Drill 11: Neural Tissue & The Nervous System
Human Anatomy and Physiology - Problem Drill 11: Neural Tissue & The Nervous System Question No. 1 of 10 The human body contains different types of tissue. The tissue is formed into organs and organ systems.
More informationTHE NERVOUS SYSTEM. Station 9 : THE SPINAL CORD
Station 9 : THE SPINAL CORD The spinal cord is a long thin bundle of nerve cells that extends from the medulla of the brainstem all the way down the vertebral column. The spinal cord is made up of gray
More informationFunctions of the Nervous System. Fundamentals of the Nervous System & Nervous Tissue
Fundamentals of the Nervous System & Nervous Tissue Overview Structure cell types & structures Neurophysiology membrane potential Synapse, neurotransmitters & receptors Functions of the Nervous System
More informationNervous System. Electrical Signals.III Signal Transmission at Synapses Neurotransmitters.V Neural Circuits.VI
Nervous System Overview.I Histology.II Electrical Signals.III Signal Transmission at Synapses Neurotransmitters.V Neural Circuits.VI Repairs.VII Pathology.VIII.IV 1 Controls and integrates all body activities
More informationBiology 218 Human Anatomy
Chapter 17 Adapted form Tortora 10 th ed. LECTURE OUTLINE A. Overview of the Nervous System (p. 537) 1. The nervous system and the endocrine system are the body s major control and integrating centers.
More informationCells of the Nervous System
Cells of the Nervous System Layout of the Nervous System Central Nervous System (CNS) Brain (in the skull) Spinal Cord (in the spine) Interprets sensory input, initiates movement, and mediates complex
More informationBiology Dr. Khalida Ibrahim Nervous system The nervous system is responsible for communication between different regions of the body, it is divided
Biology Dr. Khalida Ibrahim Nervous system The nervous system is responsible for communication between different regions of the body, it is divided into: CNS (central nervous system) = brain + spinal cord
More informationNervous tissue, charachteristics, neurons, glial cells
Nervous tissue, charachteristics, neurons, glial cells Functional Organization of Nervous Tissue The Nervous System Components Brain, spinal cord, nerves, sensory receptors Responsible for Sensory perceptions,
More informationFunctional Organization of Nervous Tissue. Nervous tissue, charachteristics, neurons, glial cells. The Nervous System. The Nervous System 21/12/2010
Nervous tissue, charachteristics, neurons, glial cells Functional Organization of Nervous Tissue The Nervous System Components Brain, spinal cord, nerves, sensory receptors Responsible for Sensory perceptions,
More informationNervous Tissue Nervous tissue is the term for groups of organized cells in the nervous system, which is the organ system that controls the body s
Nervous Tissue Nervous tissue is the term for groups of organized cells in the nervous system, which is the organ system that controls the body s movements, sends and carries signals to and from the different
More informationChapter 12: Fundamentals of the Nervous System and Nervous Tissue
Chapter 12: Fundamentals of the Nervous System and Nervous Tissue Overview of the NS PNS (Peripheral Nervous System) CNS (Central Nervous System) Neurons Neuroglia Synapse Some nomenclature Developed by
More information2401 : Anatomy/Physiology
Dr. Chris Doumen Week 5 2401 : Anatomy/Physiology Introduction Neural Tissue TextBook Readings Pages 388 through 397. Make use of the figures in your textbook ; a picture is worth a thousand words! Work
More informationTHE NEUROBIOLOGY OF THE NEURON AND THE NEUROGLIA
THE NEUROBIOLOGY OF THE NEURON AND THE NEUROGLIA DEFINITION OF A NEURON Neuron is the name given to the nerve cell and all its processes. Neurons are excitable cells that are specialized for the reception
More information25 Things To Know. Neurons
25 Things To Know Neurons Neurons receive & transmit to other cells Neurons Many last your whole life Neurons Many last your whole life Other cells die and are replaced Most aren t replaced Neurons Hippocampus
More informationNervous system Overview ( The master communication system)
Nervous system Overview ( The master communication system) Neuron process Cell body nucleus Neuroglia Nerve Tissue COMPOSITION OF NERVE TISSUE Two principal types of cells, neurons and supporting cells
More informationSabrina Jedlicka 9/20/2010 NEUROENGINEERING
Sabrina Jedlicka 9/20/2010 NEUROENGINEERING What is neuroengineering? Neuroengineering is an interdisciplinary field, combining engineering and computational approaches to problems in basic and clinical
More informationFLASH CARDS. Kalat s Book Chapter 2 Alphabetical
FLASH CARDS www.biologicalpsych.com Kalat s Book Chapter 2 Alphabetical absolute refractory period absolute refractory period Time when neuron will not re-fire no matter how much stimulus it gets. action
More informationMIDTERM EXAM 1 COGNITIVE SCIENCE 107A
MIDTERM EXAM 1 COGNITIVE SCIENCE 107A FALL 2011 Name: Points: / 100 PID: I. SHORT ANSWERS (6 points each for a total of 30 points) 1. Describe two contributions made by Ramon y Cajal (1852-1934) in terms
More informationWhat are the 6 types of neuroglia and their functions?!
Warm Up! Take out your 11C Notes What are the 6 types of neuroglia and their functions?! Astrocytes Microglia Ependymal Cells Satellite Cells Schwann Cells Oligodendrocytes Support, brace, & nutrient transfer
More informationNeural Tissue. Chapter 12 Part B
Neural Tissue Chapter 12 Part B CNS Tumors - Neurons stop dividing at age 4 but glial cells retain the capacity to divide. - Primary CNS tumors in adults- division of abnormal neuroglia rather than from
More informationHole s Human Anatomy and Physiology Eleventh Edition. Chapter 10
PowerPoint Lecture Outlines to accompany Hole s Human Anatomy and Physiology Eleventh Edition Shier Butler Lewis Chapter 10 Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction
More informationNURSE-UP INTRODUCTION TO THE NERVOUS SYSTEM
NURSE-UP INTRODUCTION TO THE NERVOUS SYSTEM FUNCTIONS OF THE NERVOUS SYSTEM Body s primary communication and control system. Integrates and regulates body function Collects information specialized nervous
More informationClass 4, part 2, Sept-29, Myelination
1 2 3 Class 4, part 2, Sept-29, Myelination Lecture by Dr. Fournier, Transcribed by Zahra Tabatabaei (Sarah) , Edited by Aki Caramanos Caramanos@gmail.com 4 5 6 7 8 9 10 11 12 13
More information10.1: Introduction. Cell types in neural tissue: Neurons Neuroglial cells (also known as neuroglia, glia, and glial cells) Dendrites.
10.1: Introduction Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Cell types in neural tissue: Neurons Neuroglial cells (also known as neuroglia, glia, and glial
More informationNeurons and Glial Cells *
OpenStax-CNX module: m44747 1 Neurons and Glial Cells * OpenStax This work is produced by OpenStax-CNX and licensed under the Creative Commons Attribution License 3.0 By the end of this section, you will
More informationNervous System. Lesson 11
Nervous System Lesson 11 Reflex Arcs 1. Patellar reflex Causes leg to kick up 2. Achilles reflex Causes foot to jerk forward 3. Triceps reflex Causes arm to straighten 4. Babinski reflex 4. Pupil Dilation
More informationHole s Human Anatomy and Physiology Tenth Edition. Chapter 10
PowerPoint Lecture Outlines to accompany Hole s Human Anatomy and Physiology Tenth Edition Shier Butler Lewis Chapter 10 Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or
More informationNeurodevelopment II Structure Formation. Reading: BCP Chapter 23
Neurodevelopment II Structure Formation Reading: BCP Chapter 23 Phases of Development Ovum + Sperm = Zygote Cell division (multiplication) Neurogenesis Induction of the neural plate Neural proliferation
More informationOutline. Neuron Structure. Week 4 - Nervous System. The Nervous System: Neurons and Synapses
Outline Week 4 - The Nervous System: Neurons and Synapses Neurons Neuron structures Types of neurons Electrical activity of neurons Depolarization, repolarization, hyperpolarization Synapses Release of
More informationDevelopment of the Nervous System 1 st month
Development of the Nervous System 1 st month day 1 - fertilization of egg day 6 - uterine implantation day 18 - trilaminar (3-layered) disc (blastoderm, embryo) ectoderm (dorsal) - nervous system and skin
More informationStrategies for nerve regeneration after CNS injury
Strategies for nerve regeneration after CNS injury Xiaodan JIANG 1 *, Shengbin Kou 1#, Zhiqiang Fa 1#, Yehai Li 1#, Zhenzhou Chen 1, Shanshan Song 2, Hongbo GUO 1, Yiquan KE 1, Ruxiang XU1, Zhicheng XIAO
More informationFunction of the Nervous System
Nervous System Function of the Nervous System Receive sensory information, interpret it, and send out appropriate commands to form a response Composed of neurons (functional unit of the nervous system)
More informationStrategies for Neuronal Regeneration after Spinal Cord Injury
Magnetic Shield Corporation. (1997). Electromagnetic Shielding. Riley, K. (1995). Tracing EMFs in Building wiring and grounding. Tucson, AZ: Magnetic Sciences International. Posted in Uncategorized Tags:
More informationNerve Cells and Behavior
Nerve Cells and Behavior 27 th September, 2016 Touqeer Ahmed Ph.D. Atta-ur-Rahman School of Applied Biosciences National University of Sciences and Technology Nervous System and Behavior Nervous system
More informationThe Nervous System 7PART A. PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College
PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College The Nervous System 7PART A Functions of the Nervous System Sensory input gathering information To monitor
More informationTeacher Key. Big Idea Different types of neurons compose the nervous tissue that forms the communication system within the body.
Big Idea Different types of neurons compose the nervous tissue that forms the communication system within the body. Introduction to Neurons An individual s survival and reproductive success depends upon
More informationNeural Tissue. Chapter 12 Part A
Neural Tissue Chapter 12 Part A Homeostasis Homeostasis refers to maintaining internal environment. How does body maintain homeostasis?? 1. Each cell, tissue or organ maintain their own internal environment
More informationNeurogenesis in Adult Central Nervous System: Death of a Dogma
Aristotle University of Thessaloniki, Greece, Nov. 2007 Neurogenesis in Adult Central Nervous System: Death of a Dogma Anton B. Tonchev Division of Cell Biology, Varna University of Medicine, Bulgaria
More informationNervous System (Part A-1) Module 8 -Chapter 14
Nervous System (Part A-1) Module 8 -Chapter 14 Overview Susie Turner, M.D. 1/9/13 Cellular structure of the nervous system Neurons Neuroglia Nervous System Divisions Central nervous system Peripheral nervous
More informationChapter Six Review Sections 1 and 2
NAME PER DATE Chapter Six Review Sections 1 and 2 Matching: 1. afferent nerves 2. autonomic nervous system 3. cell body 4. central nervous system (CNS) 5. dendrites 6. efferent nerves 7. myelin sheath
More informationTHE NERVOUS SYSTEM AS A TARGET ORGAN
THE NERVOUS SYSTEM AS A TARGET ORGAN Summary A target organ is an organ or organs of the body which adversely responds to systemic exposure of a chemical. The function of the nervous system is to communicate
More informationB108 BC Neurons and Glial Cells *
OpenStax-CNX module: m62431 1 B108 BC Neurons and Glial Cells * Melodye Gold Based on Human Biology Chapter 17.2: Neurons and Glial Cells by OpenStax Willy Cushwa This work is produced by OpenStax-CNX
More informationChapter 11 Introduction to the Nervous System and Nervous Tissue Chapter Outline
Chapter 11 Introduction to the Nervous System and Nervous Tissue Chapter Outline Module 11.1 Overview of the Nervous System (Figures 11.1-11.3) A. The nervous system controls our perception and experience
More informationWhat Cell Make Up the Brain and Spinal Cord
What Cell Make Up the Brain and Spinal Cord Jennifer LaVail, Ph.D. (http://anatomy.ucsf.edu/pages/lavaillab/index.html) What kinds of cells are these?" Neuron?" Epithelial cell?" Glial cell?" What makes
More informationA. Subdivisions of the Nervous System: 1. The two major subdivisions of the nervous system:
BIO 211: ANATOMY & PHYSIOLOGY I 1 Ch 10 A Ch 10 B CHAPTER 10 NERVOUS SYSTEM 1 BASIC STRUCTURE and FUNCTION Dr. Lawrence G. Altman www.lawrencegaltman.com Some illustrations are courtesy of McGraw-Hill.
More informationNerve Autografts, Allografts, Conduits, Wraps, and Glue. What Should I Do?
Nerve Autografts, Allografts, Conduits, Wraps, and Glue. What Should I Do? David Kahan, MD Fellow, Hand & Upper Extremity Surgery Rothman Institute at Thomas Jefferson University Outline Wallerian Degeneration
More informationThe 7 th lecture. Anatomy and Physiology For the. 1 st Class. By Dr. Ala a Hassan Mirza
The 7 th lecture In Anatomy and Physiology For the 1 st Class By Dr. Ala a Hassan Mirza Nervous System (part I) The Nerve Tissue and the Nervous System The Tissues of the Body There are 4 types of tissues
More informationsensory input receptors integration Human Anatomy motor output Ch. 7 effectors Structural classification
Human Anatomy Ch. 7 I. The Nervous System A. General characteristics 1. body s control & communication center a. 3 overlapping functions 1) sensory input: receptors monitor stimuli 2) integration: processes,
More informationThe Nervous System SBI4U
SBI4U The Nervous System Central Nervous System (CNS): consists of the brain and spinal cord Acts as the coordinating centre for incoming and outgoing information Peripheral Nervous System (PNS): consists
More informationThe cells of the nervous system
The cells of the nervous system LESSON N.9 - PSYCHOBIOLOGY because of the location and volume as compared to our body, the brain has always been a matter of conjecture about its fundamental role in the
More informationHistology. Becoming familiar with tissues of the Human Body. structure determines function
Histology Becoming familiar with tissues of the Human Body structure determines function Histology is the study of the microscopic structure of tissues. Familiarity with tissue structure is essential to
More informationCell Migration II: CNS Cell Migration. Steven McLoon Department of Neuroscience University of Minnesota
Cell Migration II: CNS Cell Migration Steven McLoon Department of Neuroscience University of Minnesota 1 Course News Coffee Hour Wednesday (Oct 18) 9:00-10:00am Surdyk s Café in Northrop Auditorium Stop
More informationGlial Cells: The Other Cells of the Nervous System
Glial Cells: The Other Cells of the Nervous System 3. Oligodendrocytes - Ensheathers of the ens Yasmin Khan and Medha S Rajadhyaksha Yasmin Khan did post doctoral work at TIFR and then joined the Life
More informationTHE NERVOUS SYSTEM. Neurons & Impulses
THE NERVOUS SYSTEM Neurons & Impulses Organization of the Nervous System: Two Major Portions: The central nervous system (CNS) and the peripheral nervous system (PNS). CNS = Brain/Spinal Cord PNS = Nerves-provide
More informationNERVOUS TISSUE. 1. Functional units of the nervous system; receive, process, store and transmit information to other neurons, muscle cells or glands.
NERVOUS TISSUE LEARNING OBJECTIVES 1. Characterize and contrast the structure of neuronal cell bodies, dendrites and axons 2. List the classification of synapses and identify the basic structures of a
More informationEvaluation and Treatment of Intra-articular Fractures. Benjamin Maxson, DO Florida Orthopaedic Institute Orthopaedic Trauma Service
Evaluation and Treatment of Intra-articular Fractures Benjamin Maxson, DO Florida Orthopaedic Institute Orthopaedic Trauma Service Disclosures Nothing to disclose Articular Fractures: Overview Require
More informationFundamentals of the Nervous System and Nervous Tissue. Nervous System. Basic Divisions of the Nervous System C H A P T E R 12.
C H A P T E R 12 Fundamentals of the Nervous System and Nervous Tissue Nervous System Sensory input Integration Motor output Figure 12.1 Basic Divisions of the Nervous System Brain CNS Spinal cord Nerves
More informationActivity-Dependent Development II April 25, 2007 Mu-ming Poo
Activity-Dependent Development II April 25, 2007 Mu-ming Poo 1. The neurotrophin hypothesis 2. Maps in somatic sensory and motor cortices 3. Development of retinotopic map 4. Reorganization of cortical
More informationChapter 12 The Nervous System INTRODUCTION TO THE NERVOUS SYSTEM. Central Nervous System (CNS): STRUCTURE BRAIN SPINAL CORD NERVES
Chapter 12 The Nervous System PowerPoint by John McGill Supplemental Notes by Beth Wyatt INTRODUCTION TO THE NERVOUS SYSTEM STRUCTURE BRAIN SPINAL CORD NERVES Central Nervous System (CNS): Brain Spinal
More informationBIOH111. o Cell Module o Tissue Module o Integumentary system o Skeletal system o Muscle system o Nervous system o Endocrine system
BIOH111 o Cell Module o Tissue Module o Integumentary system o Skeletal system o Muscle system o Nervous system o Endocrine system Endeavour College of Natural Health endeavour.edu.au 1 TEXTBOOK AND REQUIRED/RECOMMENDED
More informationThe Nervous System. Dr. ZHANG Xiong Dept. of Physiology ZJU School of Medicine.
The Nervous System Dr. ZHANG Xiong Dept. of Physiology ZJU School of Medicine Http://10.10.10.151 Part 1. Summary of the nervous system The Nervous System Central Nervous System Brain + Spinal Cord Peripheral
More informationUNIT 5 REVIEW GUIDE - NERVOUS SYSTEM 1) State the 3 functions of the nervous system. 1) 2) 3)
UNIT 5 REVIEW GUIDE - NERVOUS SYSTEM State the 3 functions of the nervous system. Briefly describe the general function(s) of each of the following neuron types: a) SENSORY NEURONS: b) INTERNEURONS: c)
More information浙江大学医学院基础医学整合课程 各论 III. The Nervous System. Dr. ZHANG Xiong Dept. of Physiology ZJU School of Medicine
The Nervous System Dr. ZHANG Xiong Dept. of Physiology ZJU School of Medicine xiongzhang@zju.edu.cn http://10.202.77.12/ 1 Part 1. Summary of the nervous system 2 The Nervous System Central Nervous System
More informationPeripheral Nerve Reconstruction
Reconstruction Following Nerve Injury, Nerve Grafts & Nerve Transfers Peripheral Nerve Reconstruction Surgical approach to nerve repair is dependent upon type of injury, gap length, nerve type, and surgeon
More informationTHE HISTORY OF NEUROSCIENCE
1. Historically, how have neuroscientists determined the function of various brain regions? 2. Describe the impact of the Phineas Gage case on the field of neuroscience. 3. Explain neuron theory. THE HISTORY
More informationThe Nervous System & Nervous tissue. Dr. Ali Ebneshahidi
The Nervous System & Nervous tissue Dr. Ali Ebneshahidi Functions of the Nervous System 1. Nervous system and endocrine system are the chief control centers in maintaining body homeostasis. 2. Nervous
More informationThe Nervous System. Nervous System Functions 1. gather sensory input 2. integration- process and interpret sensory input 3. cause motor output
The Nervous System Nervous System Functions 1. gather sensory input 2. integration- process and interpret sensory input 3. cause motor output The Nervous System 2 Parts of the Nervous System 1. central
More informationCentral Nervous System. January 7, 2016
Central Nervous System January 7, 2016 Anatomy of a neuron Cell Body (soma) Receives information from the soma s extensions (dendrites) Passes on information away from the soma towards extensions (axons)
More informationCentral Nervous System
Central Nervous System January 7, 2016 Anatomy of a neuron Cell Body (soma) Receives information from the soma s extensions (dendrites) Passes on information away from the soma towards extensions (axons)
More informationThe Neuron. Consists Of: - cell body. - Dendrites - axon - axon terminal - myelin. dendrites Axon terminal. Cell body. nucleus. axon.
The Neuron Consists Of: - cell body - Dendrites - axon - axon terminal - myelin dendrites Axon terminal Cell body nucleus myelin axon THE SYNAPSE Definition: It is a point of contact between the axon of
More information