Chapter 3. Structure and Function of the Nervous System. Copyright (c) Allyn and Bacon 2004

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1 Chapter 3 Structure and Function of the Nervous System 1

2 Basic Features of the Nervous System Neuraxis: An imaginary line drawn through the center of the length of the central nervous system, from the bottom of the spinal cord to the front of the forebrain. 2

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4 Basic Features of the Nervous System Anterior: With respect to the central nervous system, located near or toward the head. 4

5 Basic Features of the Nervous System Rostral or anterior: Toward the beak ; with respect to the central nervous system, in a direction along the neuraxis toward the front of the face. 5

6 Basic Features of the Nervous System Caudal or posterior: Toward the tail ; with respect to the central nervous system. 6

7 Basic Features of the Nervous System Dorsal: Toward the back ; with respect to the central nervous system. 7

8 Basic Features of the Nervous System Ventral: Toward the belly ; with respect to the central nervous system. 8

9 Basic Features of the Nervous System Lateral: Toward the side of the body. 9

10 Basic Features of the Nervous System Medial: Toward the middle of the body. 10

11 Basic Features of the Nervous System Ipsilateral: Located on the same side of the body. 11

12 Basic Features of the Nervous System Contralateral: Located on the opposite side of the body. 12

13 Basic Features of the Nervous System Horizontal section: A slice through the brain parallel to the ground. 13

14 Basic Features of the Nervous System Sagittal section: A slice through the brain parallel to the neuraxis and perpendicular to the ground. 14

15 Basic Features of the Nervous System Midsagittal: The plane through the neuraxis perpendicular to the ground; divides the brain into two symmetrical halves. 15

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17 Basic Features of the Nervous System Meninges Meninges: The three layers of tissue that encase the central nervous system; the dura mater, arachnoid membrane, and the pia mater. Dura mater: The outermost of the meninges, i.e. tough mother. 17

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19 Basic Features of the Nervous System Meninges Arachnoid membrane: The middle layer of the meninges, located between the dura mater and the inner pia mater. Pia mater: The layer of the meninges that clings to the surface of the brain; thin and delicate, i.e. pious mother. 19

20 Basic Features of the Nervous System Meninges Subarachnoid space: The fluid-filled space that cushions the brain; located between the arachnoid membrane and the pia mater. Cerebrospinal fluid: A clear fluid, similar to blood plasma, that fills the ventricular system of the brain and the subarachnoid space surrounding the brain and spinal cord. 20

21 Dura Mater Arachnoid Membrane Subarachnoid Space [Blood vessels and Cerebrospinal Fluid (CSF)] Pia Mater Nervous System Tissue Brain, spinal cord, cranial nerves, spinal nerves, peripheral ganglia 21

22 Basic Features of the Nervous System The Ventricular System and Production of Cerebrospinal Fluid Four hollow spaces located inside the brain. Each ventricle produces cerebrospinal fluid (CSF). CSF supports the weight of the brain. Helps reduce shock to the CNS caused by sudden head movements. 22

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24 Basic Features of the Nervous System The Ventricular System and Production of Cerebrospinal Fluid Choroid plexus: The highly vascular tissue that protrudes into the ventricles and produces cerebrospinal fluid. 24

25 Basic Features of the Nervous System Obstructive hydrocephalus: A condition in which all or some of the brain s ventricles are enlarged; caused by an obstruction that impedes the normal flow of CSF. 25

26 26

27 Development of the Central Nervous System Cerebral cortex: The ¼ thick outmost layer of gray matter of the cerebral hemispheres. 27

28 The Forebrain Forebrain: The most rostral of the three major divisions of the brain; includes the telencephalon and diencephalon. Cerebral hemisphere: One of the two major portions of the forebrain, covered by the cerebral cortex. 28

29 29

30 The Forebrain Sulcus: A groove in the surface of the cerebral hemisphere, smaller than a fissure. 30

31 The Forebrain Fissure: A major groove in the surface of the brain, larger than a sulcus. 31

32 The Forebrain Gyrus: A convolution of the cortex of the cerebral hemispheres, separated by sulci or fissures. 32

33 The Forebrain Frontal lobe: The anterior portion of the cerebral cortex 33

34 The Forebrain Parietal lobe: The region of the cerebral cortex caudal to the frontal lobe and dorsal to the temporal lobe. 34

35 The Forebrain Occipital lobe: The region of the cerebral cortex caudal to the parietal and temporal lobes. 35

36 The Forebrain Temporal lobe: The region of the cerebral cortex rostral to the occipital lobe and ventral to the parietal and frontal lobes. 36

37 The Forebrain Primary visual cortex: The credit card size region of the posterior occipital lobe whose primary input is from the visual system. 37

38 The Forebrain Primary auditory cortex: The region of the superior temporal lobe whose primary input is from the auditory system. 38

39 The Forebrain Primary somatosensory cortex: The region of the anterior parietal lobe whose primary input is from the somatosensory system. 39

40 The Forebrain Primary motor cortex: The region of the posterior frontal lobe that contains neurons that control movements of the skeletal muscles. 40

41 The Forebrain Prefrontal cortex: The region of the frontal lobe rostral to the motor association cortex. 41

42 The Forebrain Corpus callosum: A large bundle of axons that interconnects corresponding regions of the association cortex on each side of the brain. 42

43 The Forebrain Cingulate gyrus: A strip of limbic cortex lying along the lateral walls of the groove separating the cerebral hemispheres, just above the corpus callosum. 43

44 The Forebrain Limbic System Limbic system: A group pf brain regions including the anterior thalamic nuclei, amygdala, hippocampus, limbic cortex, and parts of the hypothalamus, as well as their interconnecting fiber bundles. 44

45 The Forebrain Limbic System Hippocampus: A forebrain structure of the temporal lobe, constituting an important part of the limbic system; includes the hippocampus proper, dentate gyrus, and subiculum. 45

46 The Forebrain Limbic System Amygdala: A structure in the interior of the rostral temporal lobe, containing a set of nuclei, part of the limbic system. 46

47 The Forebrain Basal Ganglia Basal ganglia: A group of subcortical nuclei in the telencephalon, the caudate nucleus, the globus pallidus, and the putamen, important parts of the motor system. 47

48 The Forebrain Diencephalon Diencephalon: A region of the forebrain surrounding the third ventricle; includes the thalamus and the hypothalamus. 48

49 The Forebrain Thalamus Thalamus: The largest portion of the diencephalon, located above the hypothalamus; contains nuclei that projects information to specific regions of the cerebral cortex and receives information from it. 49

50 The Forebrain Hypothalamus Hypothalamus: The group of nuclei of the diencephalon situated beneath the thalamus; involved in regulation of the autonomic nervous system, control of the anterior and posterior pituitary glands, integration of species typical behaviors. 50

51 51

52 The Forebrain Hypothalamus Anterior pituitary gland: The anterior part of the pituitary gland; an endocrine gland whose secretions are controlled by the hypothalamic hormones. 52

53 The Midbrain Tectum Midbrain: The mesencephalon; the central of the three major divisions of the brain. 53

54 The Midbrain Tectum Mesencephalon: The midbrain; a region of the brain that surrounds the cerebral aqueduct; includes the tectum and tegmentum. 54

55 The Midbrain Tectum Tectum: The dorsal part of the midbrain; includes the superior and inferior colliculi. 55

56 The Midbrain Tectum Brain stem: The stem of the brain, from the medulla to the diencephalon, excluding the cerebellum. 56

57 The Midbrain Tegmentum Tegmentum: The ventral part of the midbrain, includes the periaqueductal gray matter, reticular formation, red nucleus, and substantia nigra. 57

58 The Midbrain Tegmentum Reticular formation: A large network of neural tissue located in the central part of the brain stem, from the medulla to the diencephalon; plays a part in sleep arousal attention, movement, various vital reflexes. 58

59 The Midbrain Tegmentum Periaqueductal gray matter: The region of the midbrain surrounding the cerebral aqueduct; contains neural circuits involved in species-typical behaviors such as fighting and mating; involved in sensitivity to pain. 59

60 The Midbrain Tegmentum Red nucleus: A large nucleus of the midbrain that receives inputs from the cerebellum and motor cortex and sends axons to motor neurons in the spinal cord. 60

61 The Midbrain Tegmentum Substantia nigra: A darkly stained region of the tegmentum that contains neurons that communicate with the caudate nucleus and putamen in the basal ganglia; degeneration of these neurons cause Parkinson s disease. 61

62 The Hindbrain Metencephalon Hindbrain: The most caudal part of the brain; includes the metencephalon and melecephalon. 62

63 The Hindbrain Metencephalon Cerebellum: A major part of the brain located dorsal to the pons, containing the two cerebellar hemispheres, covered with the cerebellar cortex; important component of the motor system. 63

64 The Hindbrain Metencephalon Cerebellar cortex: The cortex that covers the surface of the cerebellum. 64

65 The Hindbrain Metencephalon Pons: The region of the metencephalon rostral to the medulla, caudal to the midbrain, and ventral to the cerebellum; appears to be important in sleep and arousal. 65

66 The Hindbrain Myelencephalon Medulla oblongata: The most caudal portion of the brain, located in the myelencephalon, immediately rostral to the spinal cord; includes nuclei that control vital functions such as the cardiovascular system, respiration, and skeletal muscle tone. 66

67 The Central Nervous System The Spinal Cord Spinal cord: The cord of nervous tissue that extends caudally from the medulla. 67

68 The Central Nervous System The Spinal Cord Spinal root: A bundle of axons surrounded by connective tissue that occurs in pairs, which fuse and form a spinal nerve. 68

69 The Spinal Cord Cauda equina: A bundle of spinal roots located caudal to the end of the spinal cord. Caudal block: The anesthesia and paralysis of the the lower part of the body produced by injection of a local anesthetic into the cerebrospinal fluid surrounding the cauda equina. 69

70 The Central Nervous System The Spinal Cord Dorsal root: The spinal root that contains incoming (afferent) sensory fibers. Ventral root: The spinal root that contains the outgoing (efferent) motor fibers. 70

71 The Peripheral Nervous System The Spinal Nerves Afferent axon: An axon directed toward the central nervous system, conveying sensory information. Efferent axon: An axon directed away from the central nervous system, conveying motor commands to muscles and glands. 71

72 The Peripheral Nervous System The Autonomic Nervous System Somatic nervous system: The part of the peripheral nervous system that controls the movement of skeletal muscles or transmits somatosensory information to the central nervous system. Autonomic nervous system: The portion of the peripheral nervous system that controls the body s vegetative functions. 72

73 The Peripheral Nervous System The Autonomic Nervous System The Sympathetic Division of the ANS Sympathetic division: The portion of the autonomic nervous system that controls functions that accompany arousal and expenditure of energy. 73

74 The Peripheral Nervous System The Autonomic Nervous System Parasympathetic Division of the ANS Parasympathetic division: The portion of the autonomic nervous system that controls functions that occur during a relaxed state; supports activities involved with increases in the body s supply of stored energy including salivation, gastric and intestinal motility, secretion of digestive juices, and increased blood flow to the gastrointestinal system. 74

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