AJCC 7th Edition Handbook Errata as of 9/21/10
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1 5 81 Larynx ICD-O-3 Topography Codes Delete C32.3 Laryngeal cartilage 5 81 Larynx ICD-O-3 Topography Codes Add an asterisk after C Larynx ICD-O-3 Topography Codes Add an asterisk after C Larynx ICD-O-3 Topography Codes Add below C32.9* Larynx, NOS *Stage by location of tumor bulk or epicenter Mucosal Melanoma of the ICD-O-3 Histology Code Replace with Head and Neck Esophagus and Esophagogastric Junction ICD-O-3 Histology Code Insert , after , Stomach ICD-O-3 Histology Code Insert , after , Small Intestine ICD-O-3 Histology Code Insert , after , Colon and Rectum ICD-O-3 Histology Code Insert , after , Colon and Rectum Figure 14.3 Change to image labels: T4b;R2 changed to T3;R Anus Regional Lymph Nodes In the description of the regional lymph nodes, Perirctal should read Perirectal Anus Figure New image Gastrointestinal Stromal Regional Lymph Nodes (N) delete "NX Regional lymph nodes cannot be assessed" Gastrointestinal Stromal Regional Lymph Nodes (N) Add an asterisk after "N0 No regional lymph node metastasis" Gastrointestinal Stromal ICD-O-3 Topography Codes C17.4-C17.9 change to C17.8-C Gastrointestinal Stromal ICD-O-3 Topography Codes Delete C48.1 Specified part of peritoneum (mesentery and omentum) 8/10/10 Page 1 of 6
2 Gastrointestinal Stromal ICD-O-3 Topography Codes Insert after C20.9 Rectum C48.0-C48.8 Retroperitoneum and Peritoneum Gastrointestinal Stromal Below Regional Lymph Nodes (N) box Add *If regional node status is unknown, use N0, not NX. beneath the Regional Lymph Nodes (N) box Intrahepatic Bile Ducts Summary of Changes pretreatment serum CA199 to pretreatment serum CA Gallbladder Regional Lymph Nodes (delete, periduodenal, peripancreatic,) Should now read Celiac and superior mesenteric artery node involvement is now considered distant metastatic disease Ampulla of Vater Anatomic Stage/Prognostic Stage 1A should be Stage IA (Roman numeral vs. Arabic) 24 Exocrine and Endocrine 294 Pancreas Histopathologic Type Insert "tumors that" into the following sentence: The staging system applies to all tumors that arise in the pancreas Lung Distant Metastasis (M) M1b Distant metastasis should now read M1b Distant metastasis (in extrathoracic organs) Bone Pathologic Staging (low vs. high grade) for recording stage. to (low vs. high grade) system for recording grade Bone Anatomic Stage/Prognostic G3, 4 to G3, 4 High grade Cutaneous Squamous Cell Carcinoma Primary (T)* 2 asterisks added to the end of T2 note - any size with two or more high-risk features** Cutaneous Squamous Cell Carcinoma Anatomic location The word "non" was deleted. Now reads."primary site hair-bearing lip" Merkel Cell Carcinoma Regional Lymph Nodes (N) ** Micrometastases are diagnosed after sentinel or elective lymphadenectomy now reads **Isolated tumor cells in a lymph node are classified as micrometastases (N1a) and the presence of isolated tumor cells recorded using the prognostic factor. Micrometastases are diagnosed after sentinel or elective lymphadenectomy. 8/10/10 Page 2 of 6
3 Merkel Cell Carcinoma Anatomic Stage/Prognostic Stage IIIB changed to Any T cn1/n1b/n2 M0 The following note was inserted below Anatomic Stage/Prognostic table Note: Isolated tumor cells should be considered positive nodes, similar to melanoma (see Chapter 31) Merkel Cell Carcinoma Insert below Anatomic Stage/Prognostics table Note: Isolated tumor cells should be considered positive nodes, similar to melanoma (see Chapter 31) Breast Pathologic (pn)* All of Pathologic (pn)* should be yellow shaded Breast Pathologic (pn)* pn3a through pn3c should be yellow shaded Vulva Regional Lymph Nodes (N) N1a IIIA One lymph node metastasis each 5mm or less should now read N1a IIIA One or two lymph node metastases each 5mm or less Vulva ICD-O-3 Histology Code , to , Corpus Uteri Notes on Pathologic Grading Note 1 should read Notable nuclear atypia, which exceeds that which is routinely expected for the architectural grade, increases the tumor grade by Ovary and Primary ICD-O-3 Histology Code Histology code ranges should read: Peritoneal Carcinoma , , (C56.9 only) , , , (C48.1-C48.8 only) Gestational Trophoblastic Prognostic Index Scores a score of or less, and high risk is a score of 8 or greater. to a score s of 6 or less, and high risk is a score of 7 or greater Penis Figure 40.1 Insert Ta in upper left-hand corner of figure, similar to other figures on page Prostate Pathologic (pt)* pt2 to pt4 should have blue shading 8/10/10 Page 3 of 6
4 Prostate Anatomic Stage/Prognostic * T2a should read N0 M0 PSA <20 Gleason Prostate Anatomic Stage/Prognostic * Insert above T2a N0 M0 PSA 20 Gleason 7 T2a N0 M0 PSA 10<20 Gleason Prostate Anatomic Stage/Prognostic * T2a N0 M0 PSA<20 Gleason 7 should read T2a N0 M0 PSA <20 Gleason Prostate Anatomic Stage/Prognostic * Insert after T1a-c N0 M0 PSA 10<20 Gleason 6 T2a N0 M0 PSA 10<20 Gleason Prostate 2nd paragraph, last sentence change National Cancer Database Registry to National Cancer Data Base Prostate 2nd paragraph, 2nd sentence change compared to the previous Stage groups to compared to the previous stage groups Prostate 1st paragraph, 6th line change vesicle to vesical Testis Prognostic Factors (Site Testis Prognostic Factors (Site Testis Prognostic Factors (Site- Serum tumor marker..paragraph should now read Serum tumor marker levels should be measured prior to orchiectomy, but levels after orchiectomy are used for assignment of S category, taking into account the half life of AFP and hcg. Stage grouping of classification of Stage IS requires persistent elevation of serum tumor markers following orchiectomy. Insert after Alpha fetoprotein (AFP) - half life 5-7 days Insert after Huma chorionic gonadotropin (hcg) - half life 1-3 days 8/10/10 Page 4 of 6
5 Testis Clinical Staging Testis Anatomic Stage/Prognostic Testis Anatomic Stage/Prognostic Kidney Prognostic Factors (Site- 4th & 5th sentence should read: Serum tumor markers, including AFP, hcg, and LDH, should be obtained prior to orchiectomy, but levels after orchiectomy are used to complete the status of the serum tumor markers (S), taking into account the half life of AFP and hcg. Stage grouping classification of Stage IS requires persistent elevation of serum tumor markers following orchiectomy. After S1-3 delete (measured post orchiectomy) After S1-3 delete (measured post orchiectomy) Under Clinically significant: delete Presence or absence of extranodal extension and Size of the largest tumor deposit in the lymph nodes Kidney Anatomic Stage/Prognostic Stage IIII should read: Stage II Malignant Melanoma of the Uvea Distant Metastasis (M) M1c Largest diameter of the largest metastasis 8 cm or more - should be - M1c Largest diameter of the largest metastasis 8.1 cm or more Histopathologic Type Low Grade <1.5 mm beyond the capsule should now read 1.5 mm beyond the capsule Carcinoma of the ICD-O-3 Histology Code to Lacrimal Gland Sarcoma of the Orbit ICD-O-3 Histology Code Delete , 9142, 9582 Delete Insert , , , Lymphoid Neoplasms Definitions of TNM Should be yellow shading from Node to Nx Clinically abnormal peripheral lymph nodes; no histologic confirmation Lymphoid Neoplasms Definitions of TNM Should be green shading from Visceral through M1 8/10/10 Page 5 of 6
6 Lymphoid Neoplasms Definitions of TNM Front Matter Shoud be no shading from Peripheral Blood Involvement through B2 Remove 6th Edition language from cover (please visit ww.cancerstaging.net for related product information..) 709 7th Edition Task Forces The Statistical Task Force member listing inserted before OTHER CONTRIBUTORS 8/10/10 Page 6 of 6
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