4nd Patient and Family Day
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1 4nd Patient and Family Day EBMT Slide template Barcelona 7 February 2008 EBMT 2010 Vienna, Austria ;
2 History of Stem Cell Transplantation Appelbaum et al, NEJM 2006
3 What is EBMT? Scientific, non-profit society and foundation with the mission to excel in stem cell transplantation by: Promoting basic and clinical research Registration Education Standardization Quality control Accreditation Informing patients and families
4 Where is EBMT?
5 EBMT Structure EBMT Board Executive committee Working Parties Registries Patients & families Nurses Group Committees JACIE Acute Leukaemia National EBMT Working Parties Aplastic Anaemia Autoimmune Diseases Survey Board Education Chronic Leukaemias Immunobiology Infectious Diseases Late Effects Lymphoma Paediatric Diseases Solid Tumours Austria Czech Rep France Germany Italy -Allo Italy - Auto The Netherlands Registry office Paris Total Body Irradiation Cord Blood Haemoglobinopathy Research committee Editorial Board Nuclear Accident Quality Assessment of HSC Grafts Stem Cell Research Prospective Clinical Trials Statistical Outreach Switzerland Turkey UK - BMT UK - paediatric
6 EBMT Structure EBMT Board Executive committee Working Parties Registries Patients & families Nurses Group Committees JACIE Acute Leukaemia National EBMT Working Parties Aplastic Anaemia Survey Autoimmune Diseases Board Education Chronic Leukaemias Austria Research committee Nuclear Accident Immunobiology Czech Rep Registry office Paris Editorial Board Quality Assessment of HSC Grafts France Stem Cell Research Infectious Diseases Total Body Irradiation Germany Late Effects Prospective Clinical Trials Italy -Allo Lymphoma Cord Blood Statistical Paediatric Diseases Italy - Auto Haemoglobinopathy Solid Tumours The Netherlands Outreach Switzerland Turkey UK - BMT UK - paediatric
7 EBMT Structure EBMT Board Executive committee Working Parties Registries Patients & families Nurses Group Committees JACIE Acute Leukaemia National EBMT Working Parties Aplastic Anaemia Survey Autoimmune Diseases Board Education Chronic Leukaemias Austria Research committee Nuclear Accident Immunobiology Czech Rep Registry office Paris Editorial Board Quality Assessment of HSC Grafts France Stem Cell Research Infectious Diseases Total Body Irradiation Germany Late Effects Prospective Clinical Trials Italy -Allo Lymphoma Cord Blood Statistical Paediatric Diseases Italy - Auto Haemoglobinopathy Solid Tumours The Netherlands Outreach Switzerland Turkey UK - BMT UK - paediatric
8 EBMT Structure EBMT Board Executive committee Working Parties Registries Patients & families Nurses Group Committees JACIE Acute Leukaemia National EBMT Working Parties Aplastic Anaemia Survey Autoimmune Diseases Board Education Chronic Leukaemias Austria Research committee Nuclear Accident Immunobiology Czech Rep Registry office Paris Editorial Board Quality Assessment of HSC Grafts France Stem Cell Research Infectious Diseases Total Body Irradiation Germany Late Effects Prospective Clinical Trials Italy -Allo Lymphoma Cord Blood Statistical Paediatric Diseases Italy - Auto Haemoglobinopathy Solid Tumours The Netherlands Outreach Switzerland Turkey UK - BMT UK - paediatric
9 EBMT Structure EBMT Board Executive committee Working Parties Registries Patients & families Nurses Group Committees JACIE Acute Leukaemia National EBMT Working Parties Aplastic Anaemia Survey Autoimmune Diseases Board Education Chronic Leukaemias Austria Research committee Nuclear Accident Immunobiology Czech Rep Registry office Paris Editorial Board Quality Assessment of HSC Grafts France Stem Cell Research Infectious Diseases Total Body Irradiation Germany Late Effects Prospective Clinical Trials Italy -Allo Lymphoma Cord Blood Statistical Paediatric Diseases Italy - Auto Haemoglobinopathy Solid Tumours The Netherlands Outreach Switzerland Turkey UK - BMT UK - paediatric
10 EBMT Structure EBMT Board Executive committee Working Parties Registries Patients & families Nurses Group Committees JACIE Acute Leukaemia National EBMT Working Parties Aplastic Anaemia Survey Autoimmune Diseases Board Education Chronic Leukaemias Austria Research committee Nuclear Accident Immunobiology Czech Rep Registry office Paris Editorial Board Quality Assessment of HSC Grafts France Stem Cell Research Infectious Diseases Total Body Irradiation Germany Late Effects Prospective Clinical Trials Italy -Allo Lymphoma Cord Blood Statistical Paediatric Diseases Italy - Auto Haemoglobinopathy Solid Tumours The Netherlands Outreach Switzerland Turkey UK - BMT UK - paediatric
11 EBMT Structure EBMT Board Executive committee Working Parties Registries Patients & families Nurses Group Committees JACIE Acute Leukaemia National EBMT Working Parties Aplastic Anaemia Survey Autoimmune Diseases Board Education Chronic Leukaemias Austria Research committee Nuclear Accident Immunobiology Czech Rep Registry office Paris Editorial Board Quality Assessment of HSC Grafts France Stem Cell Research Infectious Diseases Total Body Irradiation Germany Late Effects Prospective Clinical Trials Italy -Allo Lymphoma Cord Blood Statistical Paediatric Diseases Italy - Auto Haemoglobinopathy Solid Tumours The Netherlands Outreach Switzerland Turkey UK - BMT UK - paediatric
12 Achievements of EBMT > 650 articles published in leading scientific journals > 10 prospective clinical studies running > 100 retrospective studies running Consultant of the European Union Consultant of the EMEA
13 Latest developments Increasing HCT activities in Europe (> / year) Age limits disappeared (HCT > 75 years) Results of unrelated HCT increased (= related) Alternative donors: unrelated cord blood haploidentical Successful treatment of relapse after HCT
14 Evolution of RIC allogeneic HSCT in Europe H S C T Allo total HSCT RIC HSCT : final data
15 EBMT Activity Survey on HSCT changes in CML 1200 CML cp allo H S C T CML non 1st cp allo CML cp auto 300 CML non 1st cp auto : final data
16 EBMT Activity Survey on HSCT Cord blood HSCT Cord blood H S C T : final data
17 Autologous HCT - rate increased H S C T Lymphoproliferative disorders Solid tumors Leukemias Non malignant : final data
18 EBMT Activity Survey on HSCT changes in MDS/MPS H S C T MDS/MPS allo MDS/MPS auto : final data
19 EBMT Activity Survey on HSCT changes in PCD 8000 H S C T PCD auto PCD allo : final data
20 Global Activity Survey 2008 (estimate) Region Allo Auto Total The Americas Asia/Western Pacific Europe East Med/Africa Total Preliminary information: 10% increase Worldwide Network for Blood and Marrow Transplantation
21 Future plans Compare HCT with new drugs Treat GvHD better Decrease Relapse rates Consult patient and families Nuclear preparedness
22 Quality of Life After HCT
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