Adjuvant/Curative/Neo-adjuvant High Grade and Burkitt s Lymphoma Regimens. High Grade Lymphoma
|
|
- Janel Flowers
- 5 years ago
- Views:
Transcription
1 Adjuvant/Curative/Neo-adjuvant High Grade and Burkitt s Lymphoma Regimens The following table lists the evidence-informed regimens (both IV and non-iv) for high grade and Burkitt s lymphoma used in the adjuvant/curative/neo-adjuvant setting. It is expected that the prescribing oncologist will select the regimen from the list of evidence-informed regimens that is most appropriate for their patient taking account of a variety of disease-specific and patient-related factors. Regimens highlighted in red contain an expensive drug that is not currently publicly funded for the regimen and treatment intent. Regimen Code BEACOPP Etoposide 200 mg/m² IV days 1-3; DOXOrubicin 35 mg/m² IV day 1; Cyclophosphamide 1250 mg/m² IV day 1; Procarbazine 100 mg/m² PO daily, days 1-7; Prednisone 40 mg/m² PO daily, days 1-14; Bleomycin 10 mg/m² IV day 8; vincristine 1.4 mg/m 2 (max 2 mg) IV day 8. CEOP Cyclophosphamide 750 mg/m² IV day 1; Etoposide 50 mg/m² IV day 1; Etoposide 100 mg/m² PO days 2-3; Vincristine 1.4 mg/m² (max 2 mg) IV day 1; Prednisone 100 mg PO daily on days 1-5. CEOP+RITU Cyclophosphamide 750 mg/m² IV day 1; Etoposide 50 mg/m² IV day 1; Etoposide 100 mg/m² PO days 2-3; Vincristine 1.4 mg/m² (max 2 mg) IV day 1; Prednisone 100 mg PO daily on days 1-5; CEPP(B) Cyclophosphamide mg/m² IV days 1, 8; Etoposide 70 mg/m² IV days 1, 2, 3; Procarbazine 60 mg/m² PO daily, days 1-10; Prednisone 60mg/m² PO daily, days 1-10; Bleomycin 15 units/m² IV days 1, 15. Alternative Etoposide schedule: 70 mg/m² IV day 1 and 140 mg/m² PO daily, days 2 and 3
2 Procarbazine may be dropped from the regimen CEPIOP Cyclophosphamide 750 mg/m² IV day 1; epirubicin 50mg/m² IV day 1; Prednisone 100 mg PO daily, days 1-5. CEPIOP+RITU Cyclophosphamide750 mg/m² IV day 1; epirubicin 50 mg/m² IV day 1; CEPP Cyclophosphamide mg/m² IV days 1 and 8; Etoposide 70 mg/m² IV day 1; Etoposide 140 mg/m² PO days 2-3; Procarbazine 60 mg/m² PO daily, days 1-10; Prednisone 60 mg/m² PO daily, days CEPP+RITU Cyclophosphamide mg/m² IV days 1 and 8; Etoposide 70 mg/m² IV day 1; Etoposide 140 mg/m² PO day 2-3; Procarbazine 60 mg/m² PO daily, day 1-10; Prednisone 60 mg/m² PO daily, days 1-10; rituximab 375mg/m² IV day 1. CHOEP Cyclophosphamide 750 mg/m² IV day 1; Etoposide 100 mg/m² IV day 1; Etoposide 200 mg/m² PO days 2-3; Prednisone 100 mg PO daily, days 1-5. CHOEP+RITU Cyclophosphamide 750 mg/m² IV day 1; Etoposide 100 mg/m² IV day 1 ; Etoposide 200 mg/m² PO days 2-3;
3 Regimen Code CHOP Cyclophosphamide 750 mg/m² IV day 1; Prednisone 100 mg PO daily, days 1-5. CHOP+R Cyclophosphamide 750 mg/m² IV day 1; CHOP14+R Cyclophosphamide 750 mg/m² IV day 1; Q14 days CNOP Cyclophosphamide 750 mg/m² IV day 1; MitoXANTRONE 10 mg/m² IV day 1; Prednisone 50 mg/m²/day PO days 1-5. CYCLETOP Cyclophosphamide 2000 mg/m² IV day 1; Etoposide 200 mg/m² IV days 1-3. CYTAMTRX(IT) DHAP ESHAP EPOCH+RITU Schedule and frequency is variable, one option is: Methotrexate 12 mg + Cytarabine 40 mg IT +/- Hydrocortisone 15 mg IT 2 injections/week for 4 weeks CISplatin 100 mg/m² IV day 1; Cytarabine 2000 mg/m² IV over 2 hours Q12 hours x 2 doses, day 2; Dexamethasone 40 mg PO days 1-4. Etoposide 40 mg/m²/day IV days 1-4; CISplatin 25 mg/m²/day CIV days 1-4; Cytarabine 2000 mg/m² IV day 5 only; Methylprednisolone 500 mg IV days 1-5; rituximab 375 mg/m 2 IV day 1 (before starting EPOCH); Etoposide 50 mg/m 2 /day CIV days 1 to 4; vincristine 0.4 mg/m 2 /day CIV days 1 to 4; DOXOrubicin 10 mg/m 2 /day CIV days 1 to 4; Cyclophosphamide 750 mg/m 2 IV day 5; Prednisone 60 mg/m 2 PO daily or BID days 1 to 5
4 Note: this is dose-adjusted EPOCH GDP Gemcitabine 1000 mg/m² IV days 1,8; Dexamethasone 40 mg PO days 1-4; CISplatin 75 mg/m² IV day 1. HYPERCVAD Course A: Cyclophosphamide 600 mg/m² IV days 1-3 (max 1320 mg); DOXOrubicin 50 mg/m² IV day 4*; vincristine 1.4 mg/m² (max 2 mg) IV days 4* and 11; Dexamethasone 40 mg PO days 1, 2, 3, 4, 11, 12, 13, 14. *some centres may administer on day 3 HYPERCVAD+RITU Course B: Inpatient Course A: Cyclophosphamide 600 mg/m² IV days 1-3 (max 1320 mg); DOXOrubicin 50 mg/m² IV day 4*; vincristine 1.4 mg/m² (max 2 mg) IV days 4* and 11; Dexamethasone 40 mg PO days 1, 2, 3, 4, 11, 12, 13, 14; *some centres may administer on day 3 ICE Course B: Inpatient Mesna 1667 mg/m² IV days 1-3; Ifosfamide 1667 mg/m² IV days 1-3; Mesna 2000 mg PO days 1-3 (2 and 4 hours post-ifosfamide); CARBOplatin AUC 5 IV day 1; Etoposide 100 mg/m² IV days 1-3.
5 MINIBEAM MTRX(IT) Carmustine 60 mg/m² IV day 1; Etoposide 75 mg/m² IV days 2-5; Cytarabine 100 mg/m² IV Q12 hours, days 2-5; Melphalan 30 mg/m² IV day 6 (or may give 6 mg/m² IV daily for 5 days, or entire dose on day 5 for outpatient administration). Q28-42 days Methotrexate 12 mg IT Schedule and frequency depends on treatment intent and disease status (i.e. prophylactic or established CNS involvement) GDP+RITU Gemcitabine 1000 mg/m² IV days 1 and 8; Dexamethasone 40 mg PO days 1-4; CISplatin 75 mg/m² IV day 1; rituximab 375 mg/m² IV day 1 Not currently publicly funded for this regimen and intent RITU(IT) rituximab mg IT once or twice weekly for up to 8 injections not currently publicly funded for this regimen and intent
6 CODOXM Burkitt s Lymphoma : cyclophosphamide 800 mg/m² IV day 1; DOXOrubicin 40 mg/m² IV day 1; vincristine 1.5 mg/m² (max 2 mg) IV days 1, 8 (also day 15 in cycle 3); Cytarabine 70mg IT days 1, 3; cyclophosphamide 200 mg/m² IV days 2-5; Inpatient Methotrexate 1200 mg/m² IV day 10; Inpatient Methotrexate 240 mg/m² /hour x 23 hours, CIV day 10; Inpatient Leucovorin 192 mg/m² IV 12 hours post-methotrexate day 11; Inpatient Leucovorin 12 mg/m² IV Q6 hours until Methotrexate clear. CODOXM+RITU : Cyclophosphamide 800 mg/m² IV day 1; DOXOrubicin 40 mg/m² IV day 1; vincristine 1.5 mg/m² (max 2 mg) IV days 1 and 8 (also day 15 in cycle 3); Cytarabine 70 mg IT days 1 and 3; rituximab 375 mg/m² IV day 1*; Cyclophosphamide 200 mg/m² IV days 2-5; Inpatient Methotrexate 1200 mg/m² IV day 10; Inpatient Methotrexate 240 mg/m² /hour x 23 hours, CIV day 10; Inpatient Leucovorin 192 mg/m² IV 12 hours post-methotrexate day 11; Inpatient Leucovorin 12 mg/m² IV Q6 hours until Methotrexate clear. EPOCH+RITU *dose may be postponed to later in the cycle if clinically indicated rituximab 375 mg/m 2 IV day 1 (before starting EPOCH); Etoposide 50 mg/m 2 /day CIV days 1 to 4; vincristine 0.4 mg/m 2 /day CIV days 1 to 4; DOXOrubicin 10 mg/m 2 /day CIV days 1 to 4; Cyclophosphamide 750 mg/m 2 IV day 5; Prednisone 60 mg/m 2 PO daily or BID days 1 to 5 Note: this is dose-adjusted EPOCH Last Updated: February 2017
Palliative Low Grade Lymphoma & Hairy Cell Leukemia Regimens. Low Grade Lymphoma
Palliative Low Grade Lymphoma & Hairy Cell Leukemia Regimens The following table lists the evidence-informed regimens (both IV and non-iv) for low grade lymphoma and Hairy Cell leukemia used in the palliative
More informationMyeloma. Alternative Schedule: Bortezomib 1.3 mg/m² SC days 1, 4, 8, 11. Q21 days
Palliative Regimens The following table lists the evidence-informed regimens (both IV and non-iv) for myeloma used in the palliative setting. It is expected that the prescribing oncologist will select
More informationSee Important Reminder at the end of this policy for important regulatory and legal information.
Clinical Policy: (Yescarta) Reference Number: CP.PHAR.XX Effective Date: 10.31.17 Last Review Date: 11.17 Line of Business: Commercial Revision Log See Important Reminder at the end of this policy for
More informationSee Important Reminder at the end of this policy for important regulatory and legal information.
Clinical Policy: (Kymriah) Reference Number: CP.PHAR.361 Effective Date: 09.26.17 Last Review Date: 11.18 Line of Business: Commercial, Medicaid, HIM-Medical Benefit Revision Log See Important Reminder
More informationSee Important Reminder at the end of this policy for important regulatory and legal information.
Clinical Policy: Tisagenlecleucel (Kymriah) Reference Number: CP.PHAR.361 Effective Date: 10.01.18 Last Review Date: 07.13.18 Line of Business: Oregon Health Plan Revision Log See Important Reminder at
More informationEmetogenicity level 1. Emetogenicity level 2
Emetogenicity level 1 15 mins Pre-Chemo Maxalon 10mg po During chemo and Post Chemo 3 days Maxalon10mg po 8 hourly Increase Maxalon 20mg po 8 hourly Change to Cyclizine 50mg po 8 hourly 3 days If nausea
More informationGeneral Authorization Criteria for ALL Agents and Indications:
Neulasta (peg-filgrastim; G-CSF) Neupogen (filgrastim; G-CSF) Neulasta Onpro (peg-filgrastim; G-CSF) Leukine (sargramostim; GM-CSF) General Authorization Criteria for ALL Agents and Indications: Prescribed
More informationStandard Regimens for Haematology
Regimens for Haematology ChlVPP Chlorambucil 6mg/m 2 PO D1 to 14 Vinblastine 6mg/m 2 (max 10mg) IV on D1 & 8 Procarbazine 100mg/m 2 PO on D1 to 14 Prednisolone 40mg PO D1 to 14 ABVD Doxorubicin 25mg/m
More informationPharmacy Prior Authorization Colony Stimulating Factor (CSF)/Myeloid Growth Factor (MGF) Clinical Guideline
Neulasta (peg-filgrastim; G-CSF) Neupogen (filgrastim; G-CSF) Neulasta Onpro (peg-filgrastim; G-CSF) Leukine (sargramostim; GM-CSF) General Authorization Criteria for ALL Agents and Indications: Prescribed
More informationPharmacy Prior Authorization Colony Stimulating Factors Clinical Guideline. Neulasta Onpro (peg-filgrastim; G-CSF) Leukine (sargramostim; GM-CSF)
Neulasta (peg-filgrastim; G-CSF) Neupogen (filgrastim; G-CSF) Neulasta Onpro (peg-filgrastim; G-CSF) Leukine (sargramostim; GM-CSF) General Authorization Criteria for ALL Agents and Indications: Prescribed
More informationWest of Scotland Cancer Network Guideline for Managing Chemotherapy Induced Nausea and Vomiting
West of Scotland Cancer Network Guideline for Managing Chemotherapy Induced Nausea and Vomiting Definitions Acute nausea and vomiting Delayed nausea and vomiting Anticipatory nausea and vomiting Initial
More informationCLINICAL MEDICAL POLICY
CLINICAL MEDICAL POLICY Policy Name: Rituxan (rituximab) Policy Number: MP-031-MD-DE Responsible Department(s): Medical Management; Clinical Pharmacy Provider Notice Date: 10/01/2017 Issue Date: 11/01/2017
More informationFULCVR Some parts of regimen
Disease Group APPROVED REGIMENS TO BE ADMINISTERED IN L4 SITE AC AC DOCE AC DOCE+TRAS AC AC (DD) AC (DD)+TRAS AC AC +TRAS AC +TRAS (RT W) CMF(PO) CMF(PO)+TRAS DOCETRAS CYCLDOCE CYCLDOCE+TRAS FEC100 FEC
More informationDisease Site Sub-Disease Site Intent Regimen Code Regimen Details Status (as of October 17, 2017) Breast Not Applicable Adjuvant / Curative
ST-QBP Regimen Request Status for 2017/18 Below are status of regimen requests submitted for funding considerations in FY 17/18 Q1 & Q2. Requests with status will be updated on the ST-QBP website and will
More informationNON-HODGKIN LYMPHOMA TREATMENT REGIMENS: Peripheral T-Cell Lymphoma (Part 1 of 5)
Peripheral T-Cell Lymphoma (Part 1 of 5) Clinical Trials: The National Comprehensive Cancer Network recommends cancer patient participation in clinical trials as the gold standard for treatment. Cancer
More informationTransitioning Inpatient Chemotherapy to the Outpatient Setting
Transitioning Inpatient Chemotherapy to the Outpatient Setting A L I M C B R I D E, P H A R M D, M S, B C P S, B C O P C L I N I C A L C O O R D I N A T O R, T H E U N I V E R S I T Y O F A R I Z O N A
More information療指引 Classical hodgkin lymphoma
療指引 Classical hodgkin lymphoma ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) ± RT Doxorubicin 25 mg/m 2 1, 15 Q4W 1~3 Bleomycin 10 units/m 2 1, 15 Vinblastine 6 mg/m 2 1, 15 Dacarbazine 375
More informationRegimens highlighted in red contain an expensive drug that is not currently publicly funded for the regimen and treatment intent.
Palliative Breast Cancer Regimens The following table lists the evidence-informed regimens (both IV and non-iv) for breast cancer used in the palliative setting. It is expected that the prescribing oncologist
More informationSee Important Reminder at the end of this policy for important regulatory and legal information.
Clinical Policy: (Keytruda) Reference Number: CP.PHAR.322 Effective Date: 03.01.17 Last Review Date: 11.18 Line of Business: Commercial, Medicaid, HIM-Medical Benefit Revision Log See Important Reminder
More informationMASCC Guidelines for Antiemetic control: An update
MASCC / ISOO 17 th International Symposium Supportive Care in Cancer June 30 July 2, 2005 / Geneva, Switzerland MASCC Guidelines for Antiemetic control: An update Sussanne Börjeson, RN, PhD Linköping University,
More informationProtocol Number Intrathecal Methotrexate for CNS 01/02/2018 Prophylaxis in GTN Gynaecology 249
Last updated Feb 9, 2018 Revision due Protocol Name on NCCP website Tumour Group Protocol Number Intrathecal Methotrexate for CNS 01/02/2018 Prophylaxis in GTN Gynaecology 249 Two Day Etoposide CISplatin
More informationAppendix 2. Adjuvant Regimens. AC doxorubin 60 mg/m 2 every 3 weeks x 4 cycles Cyclophosphamide 600 mg/m 2
Appendix 2 Adjuvant Regimens AC doxorubin 60 mg/m 2 every 3 weeks x 4 cycles Cyclophosphamide 600 mg/m 2 CMF IV cyclophosphamide 600 mg/m 2 days 1 & 8 every 4 weeks methotrexate 40 mg/m 2 for 6 cycles
More informationDOXOrubicin, Cyclophosphamide (AC 60/600) 21 day followed by weekly PACLitaxel (80) Therapy (AC-T) 261 CARBOplatin (AUC4-6) Monotherapy-21 days
Last updated Oct 17, 2018 Tumour Group Protocol Number Protocol Name on NCCP website Breast 200 Trastuzumab (IV) Monotherapy 21 days 201 Trastuzumab (IV) Monotherapy 7 days 202 DOCEtaxel Monotherapy 100mg/m2
More informationGuidelines for the Use of Anti-Emetics with Chemotherapy
Guidelines for the Use of Anti-Emetics with The purpose of this document is to provide guidance on the rational use of anti-emetics for prevention and treatment of chemotherapy-induced nausea and vomiting
More informationProtocol Number Tumour Group Protocol Name on NCCP website 22/02/ Lung Afatinib Monotherapy 244 Gastrointestinal Regorafenib Monotherapy
Last Updated 22-Feb-18 Date of last update Protocol Number Tumour Group Protocol Name on NCCP website 22/02/2018 221 Afatinib Monotherapy 244 Gastrointestinal Regorafenib Monotherapy 249 Gynaecology Intrathecal
More informationUse of Prophylactic Growth Factors and Antimicrobials in Elderly Patients with Cancer: A
Supportive Care in Cancer Use of Prophylactic Growth Factors and Antimicrobials in Elderly Patients with Cancer: A Systematic Review of the Medicare Database Romina Sosa, Shuling Li, Julia T. Molony, Jiannong
More informationPoteligeo (mogamulizmuab-kpkc)
Poteligeo (mogamulizmuab-kpkc) Policy Number: 5.02.556 Last Review: 1/2019 Origination: 1/2019 Next Review: 1/2020 Policy Blue Cross and Blue Shield of Kansas City (Blue KC) will provide coverage for Poteligeo
More informationGUIDELINES FOR ANTIEMETIC USE IN ONCOLOGY SUMMARY CLASSIFICATION
GUIDELINES FOR ANTIEMETIC USE IN ONCOLOGY SUMMARY More than half of all cancer patients experience nausea or vomiting during the course of their treatment. If nausea or vomiting becomes severe enough,
More informationVI.2 Elements for a Public Summary VI.2.1 Overview of Disease Epidemiology Acute Nausea and Vomiting (N&V) Etiologies:
VI.2 Elements for a Public Summary VI.2.1 Overview of Disease Epidemiology Acute Nausea and Vomiting (N&V) Incidence: The incidence of acute and delayed N&V was investigated in highly and moderately emetogenic
More informationHaematology, Oncology and Palliative Care Directorate.
Anticancer Treatment for Administration on the Somerset Mobile Chemotherapy Unit The table below details the suitability of different types of anticancer treatment for administration on the Somerset Mobile
More informationCOST CONSIDERATIONS Union for International Cancer Control 2014 Review of Cancer Medicines on the WHO List of Essential Medicines!!!!!!!!!
UICCEMLCostingScenarios BackoftheEnvelope Calculations PreparedforWorkingGroupSession:19621November2014,Geneva MethodsSummary We have chosen a conservative approach, calculating cost per vial. We have
More informationGuidelines on Chemotherapy-induced Nausea and Vomiting in Pediatric Cancer Patients
Guidelines on Chemotherapy-induced Nausea Vomiting in Pediatric Cancer Patients COG Supportive Care Endorsed Guidelines Click here to see all the COG Supportive Care Endorsed Guidelines. DISCLAIMER For
More informationMedical Therapies in Ovarian Cancer The Arabic Perspectives. Mezghani Bassem -Tunisia
Tunisian Health System: Social Welfare with a Public insurance for all citizens including Indigent persons. (± Additional private insurance) Choice: Public Hospital/Private Clinics (Indigents Public H)
More informationLymphomas and multiple myeloma 12/23/2018 1
60 Lymphomas and multiple myeloma 12/23/2018 1 Lymphomas Lymphoma is cancer of the lymphatic system. Lymphomas are subdivided into two main categories: Hodgkin's lymphoma (HL) and non- Hodgkin's lymphoma
More informationInpatient Antineoplastic Medication Administration And Associated Drug Costs: Institution of a Hospital Policy Limiting Inpatient Administration
Inpatient Antineoplastic Medication Administration And Associated Drug Costs: Institution of a Hospital Policy Limiting Inpatient Administration Alexandra E. Foster, PharmD; and David J. Reeves, PharmD,
More informationClinical Policy: Bendamustine (Bendeka, Treanda) Reference Number: CP.PHAR.307 Effective Date: Last Review Date: 11.18
Clinical Policy: (Bendeka, Treanda) Reference Number: CP.PHAR.307 Effective Date: 02.01.17 Last Review Date: 11.18 Coding Implications Revision Log Line of Business: Medicaid, HIM-Medical Benefit See Important
More informationExhibit B United States Patent Application 20020012663 Kind Code A1 Waksal, Harlan W. January 31, 2002 Treatment of refractory human tumors with epidermal growth factor receptor antagonists Abstract A
More informationRelapsed/Refractory Hodgkin Lymphoma
Relapsed/Refractory Hodgkin Lymphoma Anas Younes, MD Chief, Lymphoma Service Memorial Sloan-Kettering Cancer Center New York, New York, United States Case Study 32-year-old woman was diagnosed with stage
More informationGazyva (obinutuzumab)
STRENGTH DOSAGE FORM ROUTE GPID 1000mg/40mL Vial Intravenous 35532 MANUFACTURER Genentech, Inc. INDICATION(S) Gazyva (obinutuzumab) is a CD20- directed cytolytic antibody and is indicated, in combination
More informationIndium-111 Zevalin Imaging
Indium-111 Zevalin Imaging Background: Most B lymphocytes (beyond the stem cell stage) contain a surface antigen called CD20. It is possible to kill these lymphocytes by injecting an antibody to CD20.
More informationST-QBP: Systemic Treatment Quality-Based Program (formerly STFM) DF: Drug Formulary GYNECOLOGICAL SKIN HEMATOLOGY ST- QBP
Updates from October 17, 2017 Please note that the following are regimen updates applicable to webpage documents and/or Drug Formulary s regimen monographs, as indicated by checkmarks. : Systemic Treatment
More informationLONG-TERM FOLLOW-UP OF TREATMENT OF BURKTT'S LYMPHOMA -SINGLE INSTITUTION EXPERIENCE
LONG-TERM FOLLOW-UP OF TREATMENT OF BURKTT'S LYMPHOMA -SINGLE INSTITUTION EXPERIENCE 譚傳德, 劉美瑾, 陳博文, 吳茂青, 邱倫瑋, 陳鵬宇, 吳佳興, 李明媛, 曹美華, 黃玉儀 和信治癌中心醫院血液淋巴及幹細胞移植團隊 Tran-Der Tan* 1, Mei-Ching Liu1, Mau-Ching Wu1,
More informationNCCN Non Hodgkin s Lymphomas Guidelines V Update Meeting 06/14/12 and 06/15/12
NCCN Non Hodgkin s Lymphomas Guidelines V.1.213 Update Meeting 6/14/12 and 6/15/12 Guidelines Page and Request Chronic Lymphocytic Leukemia/ Small Lymphocytic Lymphoma (CLL/SLL) Panel Discussion References
More informationADULT Updated: September 4, 2018
Updated: September 4, 2018 Regimen Reference Order ARIA: LYMP [R-CHOP alt. R-DHAP] Planned Course: Indication for Use: Every 21 days for 6 cycles (R-CHOP given on cycles 1, 3 and 5; R-DHAP given on cycles
More informationCYTARABINE: Class: Antineoplastic Agent, Antimetabolite (Pyrimidine Analog)
CYTARABINE: Class: Antineoplastic Agent, Antimetabolite (Pyrimidine Analog) Indications: - AML induction - AML consolidation -AML salvage treatment -Acute promyelocytic leukemia (APL) induction APL consolidation
More informationR-ICE Regimen- Rituximab, Etoposide, Ifosfamide (with MESNA), Carboplatin (+ Depocyte if CNS involvement)
R-ICE Regimen- Rituximab, Etoposide, Ifosfamide (with MESNA), Carboplatin (+ Depocyte if CNS involvement) Available for Routine Use in Burton in-patient Derby in-patient Burton day-case Derby day-case
More informationChange Summary - Form 2018 (R3) 1 of 12
Summary - Form 2018 (R3) 1 of 12 Form Question Number (r3) Type Description New Text Previous Text Today's date was removed 2018 N/A Today's Date Removed from Key Fields 2018 N/A HCT Type 2018 N/A Product
More informationDRUG EXTRAVASATION. Vesicants. Irritants
DRUG EXTRAVASATION Vesicants Irritants Vesicants Antineoplastic drugs Amsacrine Dactinomycin Daunorubicin Docetaxel (rare) Doxorubicin Epirubicin Idarubicin Mechlorethamine Mitomycin Oxaliplatin (rare)
More informationWho should get what for upfront therapy for MCL? Kami Maddocks, MD The James Cancer Hospital The Ohio State University
Who should get what for upfront therapy for MCL? Kami Maddocks, MD The James Cancer Hospital The Ohio State University Treatment Challenges Several effective options, improve response durations, none curable
More informationDefining the Emetogenicity of Cancer Chemotherapy Regimens: Relevance to Clinical Practice
Defining the Emetogenicity of Cancer Chemotherapy Regimens: Relevance to Clinical Practice PAUL J. HESKETH St. Elizabeth s Medical Center, Boston, Massachusetts, USA Key Words. Chemotherapy Emesis Emetogenicity
More informationNon-Hodgkin s Lymphoma
Non-Hodgkin s Lympoma Non-Hodgkin s Lymphomas Janet H. Van Cleave MSN, ACNP-CS, CS, AOCN Acute Care Nurse Practitioner The Mount Sinai Medical Center of New York City Doctoral Student, Yale University
More informationGuideline Update on Antiemetics
Guideline Update on Antiemetics Clinical Practice Guideline Special Announcements Please check www.asco.org/guidelines/antiemetics for current FDA alert(s) and safety announcement(s) on antiemetics 2 Introduction
More informationPatient 1: Patient 2:
Appendix A Compiled by Dr. Raymond Ngeh and Dr. Robert Luk Clinical notes and PET/CT scan images of eleven patients: 1. Middle age woman has cancer of the pancreas in the body of the gland. After just
More informationClinical Tools and Resources for Self-Study and Patient Education
Clinical Tools and Resources for Self-Study and Patient Education CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING CLINICIAN'S RESOURCE GUIDE The clinical tools and resources contained herein are provided as educational
More informationANAPLASTIC LARGE CELL LYMPHOMA TREATMENT ROAD MAP (Modified ALCL99)
ANAPLASTIC LARGE CELL LYMPHOMA TREATMENT ROAD MAP (Modified ALCL99) CLASSIFICATION OF TREATMENT GROUPS: 1. Isolated Skin lesions, < 5 skin lesions. Treatment course: ( No treatment, wait and see approach)
More informationLYIVAC (Magrath B) + R (rituximab) [To be used after LYCODOX-M (Magrath A) + R]
Page 1 of 7 PPO FOR THE TREATMENT OF BURKITT LYMPHOMA AND LEUKEMIA LYIVAC (Magrath B) + R (rituximab) [To be used after LYCODOX-M (Magrath A) + R] DAY DATE CHEMOTHERAPY 1 Start signature sheet and prednisolone
More informationSCI. SickKids-Caribbean Initiative Enhancing Capacity for Care in Paediatric Cancer and Blood Disorders
1.0 Introduction The (SCI) is a not-for-profit collaboration between the Hospital for Sick Children (SickKids), Toronto, Canada, and seven Caribbean health care institutions across six countries that strive
More informationThe problem. The treatment. Special situations. Brief background on HBV Definitions of HBV reactivation. The role and timing of antiviral therapy
Pr Raymond Sayegh The problem Brief background on HBV Definitions of HBV reactivation The treatment The role and timing of antiviral therapy Special situations Lone anti-hbcpositive, rituximab, BMT, reactivation
More informationChemotherapy dosing in pediatric patient. Surapon Wiangnon Suddhavej Hospital Faculty of Medicine Mahasarakham University
Chemotherapy dosing in pediatric patient Surapon Wiangnon Suddhavej Hospital Faculty of Medicine Mahasarakham University Outline Principle of chemotherapy Use of BSA in chemotherapy dosing Pharmacokinetic
More informationHodgkin and Non-Hodgkin Lymphoma (LYM) Post-Infusion Data
Hodgkin and Non-Hodgkin Lymphoma (LYM) Post-Infusion Data Registry Use Only Sequence Number: Date Received: CIBMTR Center Number: CIBMTR Research ID: Event date: / / Visit 100 day 6 months 1 year 2 years
More informationJob title: Consultant Pharmacist/Advanced Practice Pharmacist
Title : Guidelines for the Use of Antiemetics Purpose: To provide trust-wide guidance on the safe and effective use of antiemetics for the prevention and treatment of chemotherapy and radiotherapy induced
More informationB Cell Lymphoma: Aggressive
B Cell Lymphoma: Aggressive UpToDate: Introduction: Risk Factors: Biology: Symptoms: Diagnosis: Ibrutinib approved for mantle cell lymphoma as 2nd line therapy. - Aggressive lymphomas are a group of malignant
More information1 The Cancer Programs Regulation (AR 242/98) is amended by this Regulation.
Alberta Regulation 18/2005 Cancer Programs Act AMENDMENT REGULATION Filed: February 22, 2005 For information only: Made by the Minister of Health and Wellness (M.O. 9/2005) on February 17, 2005 pursuant
More informationClinical Policy: Pemetrexed (Alimta) Reference Number: CP.PHAR.368 Effective Date: Last Review Date: Line of Business: Medicaid
Clinical Policy: (Alimta) Reference Number: CP.PHAR.368 Effective Date: 10.31.17 Last Review Date: 02.18 Line of Business: Medicaid Coding Implications Revision Log See Important Reminder at the end of
More informationELECTRONIC HEALTH RECORD (EHR) ENHANCEMENTS FOR MARCH 15, 2016 SUMMARY
ELECTRONIC HEALTH RECORD (EHR) ENHANCEMENTS FOR MARCH 15, 2016 SUMMARY Problem Opening PACS Images on ipads or ibooks has Been Fixed Changes have been made in PROD to enable user credentials to be passed
More informationSubject: Palonosetron Hydrochloride (Aloxi )
09-J0000-87 Original Effective Date: 02/15/09 Reviewed: 07/09/14 Revised: 03/15/18 Subject: Palonosetron Hydrochloride (Aloxi ) THIS MEDICAL COVERAGE GUIDELINE IS NOT AN AUTHORIZATION, CERTIFICATION, EXPLANATION
More informationDisclosures WOJCIECH JURCZAK
Disclosures WOJCIECH JURCZAK ABBVIE (RESEARCH FUNDING), CELGENE (RESEARCH FUNDING); EISAI (RESEARCH FUNDING); GILEAD (RESEARCH FUNDING); JANSEN (RESEARCH FUNDING); MORPHOSYS (RESEARCH FUNDING), MUNDIPHARMA
More informationSubtype Review. Lymphoma einformation Project (LeIP) Mantle Cell Lymphoma
Subtype Review Mantle Cell Lymphoma Worldwide Network of Lymphoma Patient Groups Lymphoma einformation Project (LeIP) Working together, we can change the lymphoma landscape and achieve more for patients.
More informationSubject: Fosnetupitant-Palonosetron (Akynzeo) IV
09-J3000-01 Original Effective Date: 06/15/18 Reviewed: 05/09/18 Revised: 01/01/19 Subject: Fosnetupitant-Palonosetron (Akynzeo) IV THIS MEDICAL COVERAGE GUIDELINE IS NOT AN AUTHORIZATION, CERTIFICATION,
More informationDERBY-BURTON LOCAL CANCER NETWORK FILENAME R-IVE.DOC CONTROLLED DOC NO: HCCPG B53 CSIS Regimen Name: R-IVE. R-IVE Regimen
R-IVE Regimen Available for Routine Use in Burton in-patient Derby in-patient Burton day-case Derby day-case Burton community Derby community Burton out-patient Derby out-patient Indication Relapsed/ refractory
More informationSupplementary appendix
Supplementary appendix This appendix formed part of the original submission and has been peer reviewed. We post it as supplied by the authors. Supplement to: Younes A, Santoro A, Shipp M, et al. Nivolumab
More informationESCMID Online Lecture Library. by author
Hepatitis B virus and solid organ transplantation Prof. Hakan Leblebicioglu Department of Clinical Microbiology and Infectious Diseases Ondokuz Mayis University, Samsun, Turkey Conflict of interest Outline
More informationAn introduction to the Essential Medicines concept: balancing innovation with public health priorities
An introduction to the Essential Medicines concept: balancing innovation with public health priorities WHO HQ, Geneva 11 October 2017 Nicola Magrini Secretary, WHO Expert Committee on the Selection and
More informationX M/ (R) Dose adjusted (DA)-EPOCH-R
X M/ (R) adjusted (DA)-EPOCH-R Indication High-risk CD20+ diffuse large B cell lymphoma especially C-MYC and BCL-2 activated (i.e. double hit lymphoma) and mediastinal sclerosing (thymic) large B cell
More informationCPAG Summary Report for Clinical Panel Policy 1630 Bendamustine-based chemotherapy for first-line treatment of Mantle cell lymphoma (MCL) in adults
MANAGEMENT IN CONFIDENCE CPAG Summary Report for Clinical Panel Policy 1630 Bendamustine-based chemotherapy for first-line treatment of Mantle cell lymphoma (MCL) in adults The Benefits of the Proposition
More informationClinical Management Guideline for Small Cell Lung Cancer
Diagnosis and Staging: Key Points 1. Ensure a CT scan that is
More information(R) CODOX M / (R) IVAC
(R) CODOX M / (R) IVAC Indication Burkitt's or Burkitt's-like lymphoma, especially those with 1 or more of the following poor risk criteria: - Raised LDH level - WHO performance status 2-4 - Ann Arbor
More informationFor Health Professionals Who Care For Cancer Patients
March 2018 Volume 21, No. 3 For Health Professionals Who Care For Cancer s Inside This Issue: Editor s Choice New Programs: Nivolumab for Squamous Cell Cancer of the Head and Neck, Ibrutinib for Mantle-Cell
More informationCASE REPORT. Introduction
doi: 10.2169/internalmedicine.1686-18 http://internmed.jp CASE REPORT Gemcitabine, Dexamethasone, and Cisplatin Regimen as an Effective Salvage Therapy for High-grade B-cell Lymphoma with MYC and BCL2
More informationASSESSMENT OF THE PAEDIATRIC NEEDS CHEMOTHERAPY PRODUCTS (PART I) DISCLAIMER
European Medicines Agency Evaluation of Medicines for Human Use London, September 2006 Doc. Ref.: EMEA/384641/2006 ASSESSMENT OF THE PAEDIATRIC NEEDS CHEMOTHERAPY PRODUCTS (PART I) DISCLAIMER The Paediatric
More informationThe treatment of DLBCL. Michele Ghielmini Medical Oncology Dept Oncology Institute of Southern Switzerland Bellinzona
The treatment of DLBCL Michele Ghielmini Medical Oncology Dept Oncology Institute of Southern Switzerland Bellinzona NHL frequency at the IOSI Mantle Cell Lymphoma 6.5 % Diffuse Large B-cell Lymphoma 37%
More informationMethylprednisolone iv to po dose
Methylprednisolone iv to po dose The Borg System i Methylprednisolone iv to po dose PRESTON T. PHILLIPS A R C H I T E C T ford residence southampton, ny Methylprednisolone iv to po dose Chemotherapy. Cytarabine
More informationAPPHON/ROPPHA Guideline for the Prevention and Management of Chemotherapy Induced Nausea and Vomiting in Children with Cancer
APPHON/ROPPHA Guideline for the Prevention and Management of Chemotherapy Induced Nausea and Vomiting in Children with Cancer 5850/5980 University Avenue, PO Box 9700, Halifax, N.S. B3K 6R8 PEDIATRIC HEMATOLOGY/ONCOLOGY
More informationPixantrone monotherapy for the treatment of relapsed or refractory aggressive non-hodgkin s lymphoma
Pixantrone monotherapy for the treatment of relapsed or refractory aggressive non-hodgkin s lymphoma STA REPORT This report was commissioned by the NIHR HTA Programme as project number 10/59 Page 1 Title:
More informationNon-Hodgkin Lymphoma in Clinically Difficult Situations
Winship Cancer Institute of Emory University Non-Hodgkin Lymphoma in Clinically Difficult Situations James Armitage, MD Professor, Department of Internal Medicine Joe Shapiro Distinguished Chair of Oncology
More informationESCMID Online Lecture Library. by author
Immunosuppression and Hepatitis B Virus Reactivation Prof. Hakan Leblebicioglu, MD hakan@omu.edu.tr www.leblebicioglu.org Immunotolerance Immune Clearance HBV reactivation HBeAg+ HBeAg- HBeAb+ HBV DNA
More informationDRUG PROPERTIES YOU NEED TO KNOW
Dr. Janet Fitzakerley Summer 2013 Med 6541 Hematopoiesis and Host Defences jfitzake@d.umn.edu www.d.umn.edu/~jfitzake Page 1 of 11 DRUG PROPERTIES YOU NEED TO KNOW 1. Mechanism of action a. chemical class
More informationColony-Stimulating Factors for Febrile Neutropenia during Cancer Therapy
clinical therapeutics Colony-Stimulating Factors for Febrile Neutropenia during Cancer Therapy Charles L. Bennett, M.D., Ph.D., Benjamin Djulbegovic, M.D., Ph.D., LeAnn B. Norris, Pharm.D., and James O.
More informationChanging the landscape of treatment in Peripheral T-cell Lymphoma
Changing the landscape of treatment in Peripheral T-cell Lymphoma Luis Fayad Associate Professor MD Anderson Cancer Center Department of Lymphoma and Myeloma 1 6 What is peripheral 2008 WHO CLASSIFICATION
More informationLymphoma. Anas Younes, MD Professor of Medicine The University of Texas M. D. Anderson Cancer Center Houston, TX
Best of ASCO 2011 Lymphoma Anas Younes, MD Professor of Medicine The University of Texas M. D. Anderson Cancer Center Houston, TX RCHOP21 in DLBCL (GELA LNH-98.5 Study) Survival Probability OS (N = 399)
More informationPatterns of Chemotherapy Administration in Patients With Intermediate-Grade Non-Hodgkin s Lymphoma
Patterns of Chemotherapy Administration in Patients With Intermediate-Grade Non-Hodgkin s Lymphoma Review Article [1] October 01, 2001 By Vincent J. Picozzi, MD [2], Brad L. Pohlman, MD [3], Vicki A. Morrison,
More informationGuideline for Classification of the Acute Emetogenic Potential of Antineoplastic Medication in Pediatric Cancer Patients
Guideline for Classification of the Acute Emetogenic Potential of Antineoplastic Medication in Pediatric Cancer Patients POGO Antineoplastic Induced Nausea and Vomiting Guideline Development Panel: L.
More informationHODGKIN LYMPHOMA Updated February 2016 by Dr. Manna (PGY 5 Hematology Resident, University of Calgary)
HODGKIN LYMPHOMA Updated February 2016 by Dr. Manna (PGY 5 Hematology Resident, University of Calgary) Reviewed by Dr. Michelle Geddes (Staff Hematologist, University of Calgary) and Dr. Matt Cheung (Staff
More informationAdverse effects of anticancer drugs (Antimetabolites agents, Alkylating agents, Antimicrotubule agents, Miscellaneous agents, Immune therapies and
35 Adverse effects of anticancer drugs (Antimetabolites agents, Alkylating agents, Antimicrotubule agents, Miscellaneous agents, Immune therapies and Biologically directed therapies ) 1 1- Nausea and vomiting
More informationHave we moved beyond EPOCH for B-cell non-hodgkin lymphoma? YES!
Have we moved beyond EPOCH for B-cell non-hodgkin lymphoma? YES! Christopher Flowers, MD, MSc Associate Professor Director, Lymphoma Program Department of Hematology and Oncology Emory School of Medicine
More informationChemotherapy Induced Nausea and Vomiting (CINV) Anti-emetic Guidelines
North of England Cancer Network Chemotherapy Induced Nausea and Vomiting (CINV) Anti-emetic Guidelines Adult Oncology & Haematology Quality and safety for every patient every time For more information
More informationEssentials. Oncology Practise Essentials. Oncology Basics. Tutorial 2. Cancer Chemotherapy
Practise Practise This tutorial introduces you to the history, goals of therapy, classification, and clinical uses of chemotherapy. It also reviews some of the barriers to successful therapy. Goals and
More information