Final Program. 12:00 Poster mounting and Lunch buffet at the hotel

Transcription

1 Final Program Friday, October 31 st 12:00 Poster mounting and Lunch buffet at the hotel 13:00 Welcome by Karin Loser & Sabine Eming & Mario Rieth Short self-introduction of participants and description of expectations 14:00 14:30 Keynote lecture 1, Karin Loser, Muenster The skin immune system: regulation in health and disease 14:30 16:15 Session 1 - Inflammatory skin diseases: new mechanisms and novel therapeutic options Chairs: Karin Loser and Juliana de Castro-Kroner S. Kläschen (Bonn): Targeted treatment in cutaneous lupus erythematosus and related autoimmune disorders J. Schmidt (Bonn): Anwendung von Ruxolitinib bei kutanem Lupus erythematodes - Vergleich zwischen Zellkultur- und Mausmodell H. Friedrich (Duesseldorf): Skin rashes induced by vemurafenib are caused by a nonallergic mechanism M. Schneeweiss (Muenster): Local treatment with the Yersinia outer protein M (YopM) ameliorates ongoing psoriasis in mice C. Pfaff (Aachen): The psoriasis-associated IL-17A interferes with keratinocyte differentiation in 3D organotypic skin models N.-N. Do (Cologne): Functional consequences of Stat3-dependent macrophage activation in skin fibrosis V. Vollmer (Muenster): Cutaneous OX40/OX40 ligand signaling enhances contact allergy and atopic dermatitis by increasing the numbers of mast cells

2 16:15-16:45 Coffee break 16:45 17:45 Session 2 - Skin development and homeostasis Chairs: Sabine Eming and Jung Wang N. Ali (Cologne): Role of the polarity protein Par3 in mammalian skin homeostasis and regeneration K. Haas (Duesseldorf): The Aryl Hydrocarbon Receptor (AhR) is involved in murine skin barrier integrity Y. Üstün (Cologne): Deletion of the epidermis-derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis K. Plesser (Duesseldorf) The role of protease/par-axis on the regulation of neutrophilplatelet interactions 17:45 18:15 Keynote lecture 2, Mario Fabri, Cologne: Eaten, but not dead - mycobacteria-phagocyte interactions give an insight into human host defense against intracellular pathogens 18:15 19:45 Poster Session 1 Discussion of models and methods at the posters (even poster numbers) 19:45 Dinner buffet at the hotel 20:40 Disco-Bowling! im Red Bowl Soest Abfahrt 20:47 Uhr ab DB-Bahnhof Bad Sassendorf) 3 min bis Soest

3 Saturday, October 31 st 9:00 9:30 Keynote lecture 3, Sabine Eming, Cologne Skin wound healing as a model to understand the cellular crosstalk between the immune response and tissue regeneration 9:30 10:30 Session 3 - The skin and its interaction with microorganisms Chairs: Mario Fabri and Katharina Haas N. Sucker (Muenster): Alpha-melanocyte-stimulating hormone reduces the expansion of tumor-promoting myeloid-derived suppressor cells by suppression of TLR4 signaling C. Baumann (Muenster): Comparison of bacterial microbiota in the skin of psoriasis patients before and after systemic treatment with fumaric acid esters M. Stock (Muenster): Anti-inflammatory properties of a bacterial endopeptidase J. de Castro-Kroner (Cologne): Corticosteroid regulation of acquired immunity against intercellular pathogens 10:30-11:00 Coffee break 11:00 11:30 Keynote lecture 4, Bastian Schilling, Essen The Role of Neoantigens in Immune Checkpoint Blockade of Metastatic Melanoma 11:30 12:30 Poster Session 2 Discussion of models and methods at the posters (odd poster numbers)

4 12:30 14:00 Session 4 - Skin tumors: development and treatment (including lunch snacks) Chairs: Bastian Schilling and Anna Kläschen J. Wang (Aachen): RIPK3 is indispensable for necroptosis in malignant melanoma M. Siewert (Essen): Der Einfluss von selektiven BRAF Inhibitoren auf die Frequenz, Phänotyp und Funktionalität von NK Zellen in Patienten mit malignem Melanom M. Pollet (Duesseldorf): Regulation des Tumorsuppressors p27kip1 durch den Arylhydrokarbon Rezeptor (AhR) in humanen Keratinozyten E. Wachsmuth (Cologne): Regulation of epidermal barrier function: roles for insulin/igf- 1R and p38 stress kinase signaling 14:00 14:30 Concluding remarks: Sabine Eming & Karin Loser & Mario Rieth Participants: What did we learn? Has the Round-Table Meeting fulfilled my expectations? End of 2 nd ADF Round Table

5 Instructions for participants: Meeting Language: English Presentation: max. 10 slides, last slide outlook and problems Time of Talk: max. 10 min + 5 min Discussion Theme of Talk: Topic and results of PhD/MD thesis Poster (A0, Portrait): Theme models and methods In the poster sessions the participants shall discuss problematic methods or have the chance to find other students who are experts in methods or models, which they might need for their own projects Poster Numbers: Vollmer Verena P01 Poster Session 2 Kläschen Sophie P03 Poster Session 2 Plesser Kristin P04 Poster Session 1 Schmidt Julia P05 Poster Session 2 de Castro Kroner Juliane P06 Poster Session 1 Pfaff Carolina P07 Poster Session 2 Baumann Christoph P08 Poster Session 1 Friedrich Heike P09 Poster Session 2 Stock Martin P10 Poster Session 1 Do Nhu-Nguyen P11 Poster Session 2 Siewert Martina M. P12 Poster Session 1 Schneeweiss Maria P13 Poster Session 2 Pollet Marius P14 Poster Session 1 Ali Noelle P15 Poster Session 2 Wang Jing P16 Poster Session 1 Üstün Yasemin P17 Poster Session 2 Sucker Nadine P18 Poster Session 1 Haas Katharina P19 Poster Session 2 Wachsmuth Emmi P20 Poster Session 1