Management of Prostate Cancer in Africa. Dr David Anderson Clinical Oncologist Groote Schuur Hospital February 2017
|
|
|
- Buck McKinney
- 6 years ago
- Views:
Transcription
1 Management of Prostate Cancer in Africa Dr David Anderson Clinical Oncologist Groote Schuur Hospital February 2017
2 No disclosures to present
3 Overview Challenges
4 Africa is not a country Hans Rosling: Karolinska Institute
5 Africa lacks data GLOBOCAN, 2012
6 Overview Challenges The Problem
7 Africa population
8 New cancers in LMIC: (low & middle income countries) 1970: 15% 2008: 56% 2030: 70% Farmer et al. Lancet 2010
9 New cancers and expenditure in Africa Economist 2009
10 Distribution & Costs of cancer The Economist, 2009
11 Cost of prostate cancer (income grp) Greatest disparity of all the cancers 4000 x The Economist, 2009
12 Cost of prostate cancer (Africa) 10th biggest spender in Africa USA-2 nd Europe -4 th Asia 9th The Economist, 2009
13 Incidence of prostate cancer in Africa 3 rd overall 1 st Breast 2 nd Cervix GLOBOCAN, 2008
14 Incidence of prostate cancer in Africa GLOBOCAN, 2008
15 Death Rate of prostate cancer in Africa 3 rd overall 1 st Breast 2 nd Cervix GLOBOCAN, 2008
16 WHO, 2012
17 Summary Prostate cancer management is a major problem
18 Summary Prostate cancer management is a major problem Population is increasing Population will get older Highest prostate cancer mortality in world 3 rd highest mortality within Africa No data/registries Under spending
19 Overview Challenges The Problem Resources
20 Radiation resources in Africa Abdel-Wahab et al. Lancet 2013
21 Radiation resources in Africa Lancet, 2013
22 ABUJA TIMES 26 Oct 2016
23 Radiation resources in Africa (DIRAC 2008) Africa 54 countries 23 offer Teletherapy 200m people no RT 272 Teletherapy machines 2 x LINACS: 1 x Co60 RSA(92) Egypt (76) = 60% RSA + N.Africa = 90%
24 Brachytherapy 17 countries have HDR Published prostate brachytherapy information South Africa Egypt Tunisia Morocco Ghana Kenya
25 Summary Prostate cancer management is a major problem Only Southern and Northern Africa have adequate RT resources
26 Survey Ghana, Ethiopia, Cameroon, Zimbabwe, Kenya Ghana Ethiopia Cameroon Zimbabwe Kenya Cancer centres Oncologists Urologists Diagnosis Uro Uro Uro Uro Uro Management (Uro+Onc) (Uro+Onc) (Uro+Onc) (Uro+Onc) Uro+Onc MDT
27 Summary Prostate cancer management is a problem Only southern and northern Africa have adequate RT resources Prostate cancer is managed mostly by urologists Bulk of oncology input is palliative care
28 Overview Challenges The Problem Resources Prostate cancer in Africa: How does it present?
29 Cancer fatality rates per cancer Prostate cancer Greatest disparity 78% vs 22% The Economist, 2009
30 Worldwide Prostate mortality Prostate Int Sept 4(3):
31 Summary Prostate cancer management is a major problem Only southern and northern Africa have adequate RT resources Urologists manage prostate cancer Bulk of oncology input is palliative care Presents as metastatic disease
32 Overview Challenges The Problem Resources Prostate cancer in Africa: How does it present? Palliative care infrastructure
33 Palliative care 4 Pillars Policy Education Drug access Implementation Harding et al. Lancet 2013
34 Morphine access No hospice facility Lancet 2013
35 Summary Prostate cancer management is a major problem Only southern and northern Africa have adequate RT resources Urologists manage prostate cancer Bulk of oncology input is palliative care Presents as metastatic disease Lack of palliative resources
36 Conclusions The problem is dire Only long term solution is political National cancer control programs Registries Early detection Resource acquisition & allocation Training Education Primary health care
37 Short term solution
38 Short term solution Low Income Guidelines Clinical Radiation Publish low income articles
39 Short term solution Low Income Guidelines Clinical Radiation Publish low income articles Collaborations Training
40 Short term solution Low Income Guidelines Clinical Radiation Publish low income articles Collaborations Training Palliative Care
41 Short term solution #1 Low-Income Guidelines Kerr et al; NEJM, 2010
42 Low-income management decisions Diagnosis PSA Screening Early detection Can be diagnostic PSA: Free/total: R420/R280 Cut off for radical treatment R220/R120
43 Low-income management decisions Active surveillance Repeat Biopsy Serial PSA Mulitple clinic visits Benefits Avoid treatment
44 Survey Ghana Ethiopia Cameroon Zimbabwe Kenya Screening PSA TRUS AS low risk
45 Low-income management decisions Bill-Axelson et al. NEJM, 2014
46 Low-income management decisions Positive trial OS (18y): 56% vs 68% CSM (18y): 17% vs 28%
47
48 Low-income management decisions Wilt et al. NEJM, 2012
49 PIVOT results OS or PCSM No difference PSA>10 or Intermediate risk
50 Survey: watchful waiting Ghana Ethiopia Cameroon Zimbabwe Kenya LE<10y RT, WW WW RT, WW RT, WW RT, WW
51 Low-income management decisions Radiotherapy Split course RT 1796 patients; EBRT Biochemical free survival worse in patients with non treatment delay Ambrosio et al IJORBP, 2008
52
53
54
55 Low-income management decisions Palliative RT Cost effective comparison Single fraction RT Fractionated RT Pain killers Chemo Konski et al IJROBP, 2004
56 Low-income management decisions Metastatic disease BO Ketoconazole Diethystilbestrol CHAARTED OS 57m vs 44m 6 cycles Docetaxel High volume ds The leuprolide study group. NEJM 1984
57 Low-income management decisions CRPC Complete androgen deprivation PSA response Docetaxel OS (3m) Mitoxantrone PSA response Navelbine PFS, symptoms, PSA response Corticosteriods Low dose ketoconazole + hydrocortisone Diethystilbestrol + asprin
58 Conclusions Achievable low cost solutions Low Income Guidelines Publish low income articles Collaborations Training Palliative Care
National Prostate Cancer Audit. Bill Cross June 2015
National Prostate Cancer Audit Bill Cross June 2015 National Prostate Cancer Audit aim of assessing the process of care and its outcomes in men diagnosed with prostate cancer in England and Wales National
Radiation Therapy in Africa
Radiation Therapy in Africa Surbhi Grover, MD MPH Senior Lecturer, School of Medicine, University of Botswana Oncology Consultant, Princess Marina Hospital, Botswana Assistant Professor, Dept of Radiation
Does RT favor RP in long term Quality of Life? Juanita Crook MD FRCPC Professor of Radiation Oncology University of British Columbia
Does RT favor RP in long term Quality of Life? Juanita Crook MD FRCPC Professor of Radiation Oncology University of British Columbia Disclosures Advisory Board/honoraria: Varian Advisory Board: Breast
Updates in Prostate Cancer Treatment 2018
Updates in Prostate Cancer Treatment 2018 Mountain States Cancer Conference Elaine T. Lam, MD November 3, 2018 Learning Objectives Understand the difference between hormone sensitive and castration resistant
Prostate Cancer. Dr. Andres Wiernik 2017
Prostate Cancer Dr. Andres Wiernik 2017 Objectives YES!!! 1. Epidemiology 2. Biology or Natural History of Prostate Cancer 3. Treatment NO!!! 1. Prostate Cancer Screening - controversies Which is the most
18-Oct-16. Take home messages. An update for GPs on modern radiation therapy & hormones for prostate cancer. Session plan
An update for GPs on modern radiation therapy & hormones for prostate cancer A/Prof Jeremy Millar Director Radiation Oncology, Alfred Health Clinical lead Prostate Cancer Outcomes Registry, Monash University
Management of Prostate Cancer
Management of Prostate Cancer An ESMO Perspective Alan Horwich Conflicts of Interest Disclosure Alan Horwich I have no personal conflicts of interest relating to prostate cancer. European Incidence and
Managing Prostate Cancer After Initital Treatment Fails: Are There Good Next Steps?
Managing Prostate Cancer After Initital Treatment Fails: Are There Good Next Steps? Michael J Zelefsky, M.D. Professor of Radiation Oncology Chief Brachytherapy Service Department of Radiation Oncology
Prostate Cancer in men with germline DNA repair deficiency
Prostate Cancer in men with germline DNA repair deficiency Bruce Montgomery, MD Professor, Medicine and Urology Univ Washington, Fred Hutchinson CRC VA Puget Sound HCS Disclosures Company Tokai, ESSA,
CLINICAL TRIALS Open clinical uro-oncology trials in Canada George Rodrigues, MD, Eric Winquist, MD
Open clinical uro-oncology trials in Canada George Rodrigues, MD, Eric Winquist, MD London Health Sciences Centre, London, Ontario, Canada bladder cancer AN OPEN-LABEL, MULTICENTER, RANDOMIZED PHASE II
7/30/2017. One World Medical Physics: Challenges and Opportunities in Cancer Care. Worldwide Demographic Shift
People 60 Years and Older ( in Millions) 7/30/2017 One World Medical Physics: Challenges and Opportunities in Cancer Care Jatinder R Palta PhD, FAAPM, FASTRO, FACR Virginia Commonwealth University, and
Stereotactic Ablative Radiotherapy for Prostate Cancer
Stereotactic Ablative Radiotherapy for Prostate Cancer Laurie Cuttino, MD Associate Professor of Radiation Oncology VCU Massey Cancer Center Director of Radiation Oncology Sarah Cannon Cancer Center at
Table 1 Standards and items to set up a PCU: general requirements and critical mass
Table 1 Standards and items to set up a PCU: general requirements and critical mass General requirements and European Prostate Cancer Units are structures managing sufficient volumes of patients with on-site
Localized Prostate Cancer Have we finally got it right? Shingai Mutambirwa Professor & Chair-Division Urology DGMAH & SMU Pretoria SOUTH AFRICA
Localized Prostate Cancer Have we finally got it right? Shingai Mutambirwa Professor & Chair-Division Urology DGMAH & SMU Pretoria SOUTH AFRICA ESMO Cape Town 14 Feb 2018 Disclosures Advisory boards/lecturer/consultant-
Motto- Our well-being is a product of meaning we create!
Physician- Dr. Brandon Fisher Born in Utah- USA Radiation Oncology in Utah Philanthropist President -RadiatingHope Board of Directors - Above and Beyond Cancer Mountain climber Weber County Search and
Open clinical uro-oncology trials in Canada Eric Winquist, MD, George Rodrigues, MD
Open clinical uro-oncology trials in Canada Eric Winquist, MD, George Rodrigues, MD London Health Sciences Centre, London, Ontario, Canada BLADDER CANCER A MULTICENTRE, RANDOMIZED PLACEBO-CONTROLLED, DOUBLE-BLIND
Overview of Radiotherapy for Clinically Localized Prostate Cancer
Session 16A Invited lectures: Prostate - H&N. Overview of Radiotherapy for Clinically Localized Prostate Cancer Mack Roach III, MD Department of Radiation Oncology UCSF Helen Diller Family Comprehensive
Open clinical uro-oncology trials in Canada
Open clinical uro-oncology trials in Canada Eric Winquist, MD, George Rodrigues, MD London Health Sciences Centre, London, Ontario, Canada bladder cancer A PHASE II PROTOCOL FOR PATIENTS WITH STAGE T1
Open clinical uro-oncology trials in Canada Eric Winquist, MD, George Rodrigues, MD
CLINICAL TRIALS Open clinical uro-oncology trials in Canada Eric Winquist, MD, George Rodrigues, MD London Health Sciences Centre, London, Ontario, Canada bladder cancer A PHASE II PROTOCOL FOR PATIENTS
ACTIVE SURVEILLANCE OR WATCHFUL WAITING
Prostate Cancer ACTIVE SURVEILLANCE OR WATCHFUL WAITING María Teresa Bourlon, MD MS Head, Urologic Oncology Clinic Hemato-Oncology Department Instituto Nacional de Ciencias Médicas y Nutrición Salvador
Open clinical uro-oncology trials in Canada
Open clinical uro-oncology trials in Canada Eric Winquist, MD, George Rodrigues, MD London Health Sciences Centre, London, Ontario, Canada bladder cancer A PHASE II PROTOCOL FOR PATIENTS WITH STAGE T1
PROSTATE CANCER SURVEILLANCE
PROSTATE CANCER SURVEILLANCE ESMO Preceptorship on Prostate Cancer Singapore, 15-16 November 2017 Rosa Nadal National Cancer Institute, NIH Bethesda, USA DISCLOSURE No conflicts of interest to declare
Session VI A: Prostate Cancer Multidisciplinary Approach: a key to success
EORTC-GU Group Session VI A: Prostate Cancer Multidisciplinary Approach: a key to success Joaquim Bellmunt Geriatric Oncology: Cancer in Senior Adults. Madrid Melia Castilla, 8-10 November 2007. Multidisciplinary
Prostate Cancer Incidence
Prostate Cancer: Prevention, Screening and Treatment Philip Kantoff MD Dana-Farber Cancer Institute Professor of fmedicine i Harvard Medical School Prostate Cancer Incidence # of patients 350,000 New Cases
NICE BULLETIN Diagnosis & treatment of prostate cancer
Diagnosis & treatment of prostate cancer NICE provided the content for this booklet which is independent of any company or product advertised Diagnosis and treatment of prostate cancer Introduction In
Quality of Life After Modern Treatment Options for Prostate Cancer Ronald Chen, MD, MPH
Quality of Life After Modern Treatment Options I will be presenting some recently published data on the quality of life after modern treatment options for prostate cancer. My name is Dr. Ronald Chen. I'm
Excellence and Originality from Necessity: Palliative Care in Africa. Dr Emmanuel Luyirika Executive Director, African Palliative Care Association
Excellence and Originality from Necessity: Palliative Care in Africa Dr Emmanuel Luyirika Executive Director, African Palliative Care Association Summary of the presentation 1. Introduction 2. Background
High Risk Localized Prostate Cancer Treatment Should Start with RT
High Risk Localized Prostate Cancer Treatment Should Start with RT Jason A. Efstathiou, M.D., D.Phil. Assistant Professor of Radiation Oncology Massachusetts General Hospital Harvard Medical School 10
Hypofractionated RT in Cervix Cancer. Anuja Jhingran, MD
Hypofractionated RT in Cervix Cancer Anuja Jhingran, MD Hypofractionated RT in Cervix Cancer: Clinicaltrials.gov 919 cervix trials 134 hypofractionated RT trials Prostate, breast, NSCLC, GBM 0 cervix trials
End Cervical Cancer: Prevent, Treat, Care
End Cervical Cancer: Prevent, Treat, Care UN Joint Global Programme on Cervical Cancer Prevention and Control #cxca JOINT PROGRAMME MEMBERS PRIORITIES COUNTRY LEVEL Support countries in the design and
NCDB Special Study: Post-Active Treatment Surveillance in Prostate Cancer. Project Overview Ronald C. Chen, MD MPH
NCDB Special Study: Post-Active Treatment Surveillance in Prostate Cancer Project Overview Ronald C. Chen, MD MPH Introductions Principal Investigator: Ronald C. Chen, MD MPH ACS Staff: Eileen Tonner,
Debate: Whole pelvic RT for high risk prostate cancer??
Debate: Whole pelvic RT for high risk prostate cancer?? WPRT well, at least it ll get the job done.or will it? Andrew K. Lee, MD, MPH Associate Professor Department of Radiation Oncology Using T-stage,
NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE. Single Technology Appraisal (STA)
Thank you for agreeing to give us a statement on your organisation s view of the technology and the way it should be used in the NHS. Healthcare professionals can provide a unique perspective on the technology
3/22/2014. Goals of this Presentation: in 15 min & 5 min Q & A. Radiotherapy for. Localized Prostate Cancer: What is New in 2014?
3/22/ Goals of this Presentation: in 15 min & 5 min Q & A 1. Potency Preservation. a. Dosimetric considerations Radiotherapy for b. Drugs 2. Update on duration of short term ADT Mack III, MD Professor
Advanced Prostate Cancer
Advanced Prostate Cancer January 13, 2017 Sindu Kanjeekal MD FRCPC Medical Oncology and Hematology Regional Systemic Quality Lead Erie St Clair Adjunct Professor Schulich School of Medicine and University
METASTATIC PROSTATE CANCER MANAGEMENT K I R U B E L T E F E R A M. D. T R I H E A LT H C A N C E R I N S T I T U T E 0 1 / 3 1 /
METASTATIC PROSTATE CANCER MANAGEMENT K I R U B E L T E F E R A M. D. T R I H E A LT H C A N C E R I N S T I T U T E 0 1 / 3 1 / 2 0 1 8 Prostate Cancer- Statistics Most common cancer in men after a skin
Session V: The Programme of Action for Cancer Therapy - PACT
Session V: The Programme of Action for Cancer Therapy - PACT Ms Nelly Enwerem-Bromson Director Division of Programme of Action for Cancer Therapy Department of Technical Cooperation International Atomic
Understanding the risk of recurrence after primary treatment for prostate cancer. Aditya Bagrodia, MD
Understanding the risk of recurrence after primary treatment for prostate cancer Aditya Bagrodia, MD Aditya.bagrodia@utsouthwestern.edu 423-967-5848 Outline and objectives Prostate cancer demographics
Where are we with PSA screening?
Where are we with PSA screening? Faculty/Presenter Disclosure Rela%onships with commercial interests: None Disclosure of Commercial Support This program has received no financial support. This program
Date Modified: March 31, Clinical Quality Measures for PQRS
Date Modified: March 31, 2015 2015 Clinical Quality s for PQRS # Domain Title Description Type Denominator Numerator Denominator Exclusions/Exceptions 1 Patient Safety Prostate Biopsy Antibiotic Process
SIMPOSIO. Radioterapia stereotassica e nuovi farmaci nel tumore e della prostata metastatico
SIMPOSIO Radioterapia stereotassica e nuovi farmaci nel tumore e della prostata metastatico Definition of Oligometastatic PCa 1-3 synchronous metastases (bone and/or lymph nodes) 2-5 synchronous metastases
17/07/2014. Prostate Cancer Watchful Waiting New Treatments Andrew Williams Urologist and Urological Oncologist ADHB, CMDHB and 161 Gillies Ave, Epsom
My Biases Prostate Cancer Watchful Waiting New Treatments Andrew Williams Urologist and Urological Oncologist ADHB, CMDHB and 161 Gillies Ave, Epsom I am a member of the specialist group of the Prostate
Prostate Cancer: from Beginning to End
Prostate Cancer: from Beginning to End Matthew D. Katz, M.D. Assistant Professor Urologic Oncology Robotic and Laparoscopic Surgery University of Arkansas for Medical Sciences Winthrop P. Rockefeller Cancer
Prostate Cancer Genomics When To Treat and With What? Ashley E. Ross, M.D., Ph.D. Texas Urology Specialists August 2017
Prostate Cancer Genomics When To Treat and With What? Ashley E. Ross, M.D., Ph.D. Texas Urology Specialists August 2017 Relevant Disclosures Advisory role, ownership interest, previous unrestricted grant
Modern Dose Fractionation and Treatment Techniques for Definitive Prostate RT
Modern Dose Fractionation and Treatment Techniques for Definitive Prostate RT Daniel J Bourgeois, III MD, MPH Board Certified Radiation Oncologist Southeast Louisiana Radiation Oncology Group (SLROG) Disclosures
Optimizing Quality of Life through Palliative Care for Adults and Children affected by Cancer
Optimizing Quality of Life through Palliative Care for Adults and Children affected by Cancer The Public Health need for Palliative Care for Adults and Children with Cancer Dr Emmanuel Luyirika 105M-T3
Radiotherapy Physics and Equipment
Radiological Sciences Department Radiotherapy Physics and Equipment RAD 481 Lecture s Title: Introduction Dr. Mohammed EMAM Ph.D., Paris-Sud 11 University Vision :IMC aspires to be a leader in applied
Date Modified: May 29, Clinical Quality Measures for PQRS
Date Modified: May 29, 2014 Clinical Quality s for PQRS # Domain Type Denominator Numerator Denominator Exclusions/Exceptions Rationale QCDR-1 QCDR-2 Patient Safety 102 Efficiency and Cost Reduction QCDR-3
ESMO SUMMIT MIDDLE EAST 2018
ESMO SUMMIT MIDDLE EAST 2018 Management of Prostate Cancer in the Middle East Deborah Mukherji, MD, AUBMC, Beirut, Lebanon (Fadi Farhat, MD, MHHM) 6-7 April 2018, Dubai, UAE CONFLICT OF INTEREST DISCLOSURE
In autopsy, 70% of men >80yr have occult prostate ca
Prostate Cancer UpToDate: Introduction: Risk Factors: Biology: Symptoms: Diagnosis: Two randomized trials showed survival benefit of adding docetaxol to ADT in fit man with very high localized disease
Open clinical uro-oncology trials in Canada George Rodrigues, MD, Mary J. Mackenzie, MD, Eric Winquist, MD
Open clinical uro-oncology trials in Canada George Rodrigues, MD, Mary J. Mackenzie, MD, Eric Winquist, MD London Health Sciences Centre, London, Ontario, Canada BLADDER CANCER A MULTICENTRE, RANDOMIZED
Percentage of patients who underwent endoscopic procedures following SWL
Non-QPP Measures Measure ID Measure Title Definition Type Domain 1 AQUA12 Benign Prostate Hyperplasia: IPSS improvement after diagnosis Percentage of patients with NEW diagnosis of clinically significant
Appendix 4 Urology Care Pathways
Appendix 4 Urology Care Pathways Cancer Care Pathways outline the steps and stages in the patient journey from referral through to diagnostics, staging, treatment, follow up, rehabilitation and if applicable
IAEA Support for Radiotherapy Services for Patients with Cervical Cancer
IAEA Support for Radiotherapy Services for Patients with Cervical Cancer Kirsten Hopkins Applied Radiation Biology and Radiotherapy Section Division of Human Health Hugely Important to IAEA Fourth commonest
The 1 st. FARO Council Meeting. May 30, 2015 Kyoto International conference center, Japan
The 1 st FARO Council Meeting May 30, 2015 Kyoto International conference center, Japan Thai Association of Therapeutic Radiology and Oncology (THASTRO) 9 th Floor, Royal Golden Jubilee Building, Soi Soonvijai,
Breast Cancer in the Eastern Mediterranean Region A Burden with Potential. King Hussein Cancer Center
Breast Cancer in the Eastern Mediterranean Region A Burden with Potential Presented by: Mahmoud M. Sarhan, MD, MMM, CPE CEO & Director General Presented at: International Symposium on Breast Cancer in
Prostate Cancer UK Best Practice Pathway: ACTIVE SURVEILLANCE
Prostate Cancer UK Best Practice Pathway: ACTIVE SURVEILLANCE Low risk localised PSA < 10 ng/ml and Gleason score 6, and clinical stage T1 - T2a Intermediate risk localised PSA 10-20 ng/ml, or Gleason
Prostate Cancer Update 2017
Prostate Cancer Update 2017 Arthur L. Burnett, MD, MBA, FACS Patrick C. Walsh Distinguished Professor of Urology The James Buchanan Brady Urological Institute The Johns Hopkins Medical Institutions Baltimore,
Management of castrate resistant disease: after first line hormone therapy fails
Management of castrate resistant disease: after first line hormone therapy fails Rob Jones Consultant in Medical Oncology Beatson Cancer Centre Glasgow Relevant Disclosure I have received research support
Stereotactic body radiation therapy in oligometastatic patient with lymph node recurrent prostate cancer: a single centre experience.
Stereotactic body radiation therapy in oligometastatic patient with lymph node recurrent prostate cancer: a single centre experience. Elisabetta Ponti MD, Gianluca Ingrosso MD, Alessandra Carosi PhD, Luana
Optimizing Outcomes in Advanced Prostate Cancer
Optimizing Outcomes in Advanced Prostate Cancer Module 3: Focus on Recent CRPC Guidelines and Advanced Hormone-Sensitive Disease Sébastien J. Hotte, MD, MSc (HRM), FRCPC Medical Oncologist and Head, Phase
X, Y and Z of Prostate Cancer
X, Y and Z of Prostate Cancer Dr Tony Michele Medical Oncologist Prostate cancer Epidemiology Current EUA (et al) guidelines on Advanced Prostate Cancer Current clinical management in specific scenarios
Global Strategies to Improve Cancer Care and Control
Women s Empowerment Cancer Advocacy Network (WE CAN) Conference Global Strategies to Improve Cancer Care and Control Tbilisi, Georgia October 15-16, 2013 Julie R. Gralow, M.D. Jill Bennett Endowed Professor
Prostate Cancer: 2010 Guidelines Update
Prostate Cancer: 2010 Guidelines Update James L. Mohler, MD Chair, NCCN Prostate Cancer Panel Associate Director for Translational Research, Professor and Chair, Department of Urology, Roswell Park Cancer
Medical Treatments for Prostate Cancer
Medical Treatments for Prostate Cancer Ian F Tannock MD, PhD Daniel E Bergsagel Professor of Medical Oncology, Princess Margaret Hospital and University of Toronto March 17, 2005 Brampton 1 A hypothetical
Clinical Case Conference
Clinical Case Conference Intermediate-risk prostate cancer 08/06/2014 Long Pham Clinical Case 64 yo man was found to have elevated PSA of 8.65. TRUS-biopies were negative. Surveillance PSA was 7.2 in 3
Management of castrate resistant disease: after first line hormone therapy fails
Management of castrate resistant disease: after first line hormone therapy fails Rob Jones Consultant in Medical Oncology Beatson Cancer Centre Glasgow Rhona McMenemin Consultant in Clinical Oncology The
ADVANCES IN METASTATIC HORMONE-SENSITIVE PROSTATE CANCER. ALICIA K. MORGANS, MD, MPH Associate Professor of Medicine Northwestern University, USA
ADVANCES IN METASTATIC HORMONE-SENSITIVE PROSTATE CANCER ALICIA K. MORGANS, MD, MPH Associate Professor of Medicine Northwestern University, USA MAY 2018 DISCLAIMER Please note: The views expressed within
Radical Prostatectomy: Management of the Primary From Localized to Oligometasta:c Disease
Radical Prostatectomy: Management of the Primary From Localized to Oligometasta:c Disease Disclosures I do not have anything to disclose Sexual function causes moderate to severe distress 2 years after
African Cancer Fellowship Awarded Fellows
African Cancer Fellowship Awarded Fellows In collaboration with ACS, UICC is pleased to announce the awardees of the 2017 African Cancer Fellowship programme. (*) denotes UICC member Name of Fellow Ben
Secondary Hormonal therapies in mcrpc
Secondary Hormonal therapies in mcrpc Ravindran Kanesvaran Consultant,Division of Medical Oncology National Cancer Centre Singapore 1 Disclosures Research Support/P.I. Sanofi Consultant Major Stockholder
Screening and Diagnosis Prostate Cancer
Screening and Diagnosis Prostate Cancer Daniel Heng MD MPH FRCPC Chair, Genitourinary Tumor Group Tom Baker Cancer Center University of Calgary, Canada @DrDanielHeng Outline Screening Evidence Recommendations
Protocol. This trial protocol has been provided by the authors to give readers additional information about their work.
Protocol This trial protocol has been provided by the authors to give readers additional information about their work. Protocol for: Wilt TJ, Brawer MK, Jones KM, et al. Radical prostatectomy versus observation
PROSTATE CANCER STRATIFIED FOLLOW UP. Hilary Baker Lead CNS for Uro-oncology MSc, BSc, RGN.
PROSTATE CANCER STRATIFIED FOLLOW UP Hilary Baker Lead CNS for Uro-oncology MSc, BSc, RGN. LEARNING OBJECTIVES To refresh your knowledge about prostate cancer. To discuss the purpose and patient benefits
Resource-adapted guidelines for Breast Cancer Management Antwerp, Anvers Belgium February 5-7, 2015
Resource-adapted guidelines for Breast Cancer Management Antwerp, Anvers Belgium February 5-7, 2015 Nagi S. El Saghir, MD, FACP Professor & Director, Breast Center of Excellence Naef K. Basile Cancer Institute
Risk Migration ( ct2c=high)
Risk Migration ( ctc=high) Prostate Cancer Over- Detection, but Selective Treatment Active Surveillance Peter R. Carroll, MD, MPH Department of Urology University of California, San Francisco February,
Radiotherapy in Africa: Current needs and prospects
SPECIL REPORT Radiotherapy in frica: Current needs and prospects In many countries, cancer control strategies are urgently needed by F.. Durosinmi-Etti, M. Nofal, and M. M. Mahfouz Country lgeria Cameroon*
CANCER RADIOTHERAPY IN GHANA
76-80 - Vanderpuye.qxp_2016 21/12/2017 08:36 Page 76 CANCER IN GHANA VERNA VANDERPUYE (LEFT), CONSULTANT CLINICAL ONOCOLOGIST, KORLE BU TEACHING HOSPITAL, ACCRA, GHANA AND NAA ADORKOR ARYEETEY (RIGHT),
Chemotherapy for Urological Cancers
Chemotherapy for Urologic Cancers Matthew Rettig, MD Associate Professor Department of Medicine Division of Hematology-Oncology Department of Urology Medical Director, Prostate Cancer Program Institute
Embracing Technology & Timing of Salvage Hormones
Embracing Technology & Timing of Salvage Hormones Andrew Loblaw BSc, MD, MSc, FRCPC, CIP Department of Radiation Oncology Sunnybrook Health Sciences Centre University of Toronto Us Too, Brampton October
Section 1 - Standards and items to set up a PCU: general requirements and critical mass.
Section 1 - Standards and items to set up a PCU: general requirements and critical mass. 0 Mandatory requirements Critical mass 1. European Prostate Cancer Units are structures managing sufficient volume
Definition Prostate cancer
Prostate cancer 61 Definition Prostate cancer is a malignant neoplasm that arises from the prostate gland and the most common form of cancer in men. localized prostate cancer is curable by surgery or radiation
Access to Radiotherapy: Bridging The Gap Through Innovation
Access to Radiotherapy: Bridging The Gap Through Innovation Mack Roach III, MD, FACR, FASTRO University of California San Francisco Andy Grove says: A fundamental rule in technology says that whatever
Advances in Treatment of Cancer by Brachytherapy in Kenya, in Particular, Prostate Cancer
Research Article imedpub Journals www.imedpub.com Journal Of Medical Physics And Applied Sciences ISSN 2574-285X DOI: 1.21767/2574-285X.12 Advances in Treatment of Cancer by Brachytherapy in Kenya, in
Case histories in Urological cancers
Case histories in Urological cancers Dr Alison Tree Consultant Clinical oncologist, The Royal Marsden and Institute of Cancer Research 2 The Royal Marsden Outline of talk Case histories for: Localised
Prostate Cancer Patients Charter. The care that you deserve
Prostate Cancer Patients Charter The care that you deserve Prostate Cancer Patients Charter The Irish Cancer Society is committed to achieving world class cancer services in Ireland. This Charter will
CLINICAL WORKSHOP IMAGE-GUIDED HDR BRACHYTHERAPY OF PROSTATE CANCER
CLINICAL WORKSHOP IMAGE-GUIDED HDR BRACHYTHERAPY OF PROSTATE CANCER Klinikum Offenbach Nucletron April 27 th 28 th, 2014 History HDR Protocols for Boost and Monotherapy, Results, Logistics and Practical
Measuring the value of healthcare activities. Susan Rollason, Director of Finance and Strategy
Measuring the value of healthcare activities Susan Rollason, Director of Finance and Strategy Items covered What are we doing and why? What have we done so far? What challenges have we faced? What are
MAMTA PARIKH, MD, MS CHALLENGING CASE #2: GU CANCER & STATE OF THE ART: CASTRATION RESISTANT PROSTATE CANCER
MAMTA PARIKH, MD, MS CHALLENGING CASE #2: GU CANCER & STATE OF THE ART: CASTRATION RESISTANT PROSTATE CANCER NO RELEVANT FINANCIAL RELATIONSHIPS IN THE PAST TWELVE MONTHS BY PRESENTER OR SPOUSE/PARTNER.
Cancer Control Joint Action, Improving Outcomes for Cancer Patients and the European Cancer Patient s Bill of Rights
Cancer Control Joint Action, Improving Outcomes for Cancer Patients and the European Cancer Patient s Bill of Rights Second CANCON Stakeholder Forum 12 May 2015 Belgian Ministry of Health, Brussels EQUITY
International Medical Physics Education and Training Needs Over the Next 20 Years
Departments of Oncology and Medical Biophysics International Medical Physics Education and Training Needs Over the Next 20 Years Jacob (Jake) Van Dyk Professor Emeritus London, Ontario, Canada Objectives
Economic Implications of Advancements in Radiation Technology. Dramatic Growth of RT Capacity in the US
Economic Implications of Advancements in Radiation Technology Sponsored by: OTN Anthony M. Berson, M.D. Radiation Oncology, St. Vincent s Comprehensive Cancer Center Richard Emery Vice President, Aptium
Prostate Overview Quiz
Prostate Overview Quiz 1. The path report reads: Gleason 3 + 4 = 7. The Gleason s score is a. 3 b. 4 c. 7 d. None of the above 2. The path report reads: Moderately differentiated adenocarcinoma of the
2015 myresearch Science Internship Program: Applied Medicine. Civic Education Office of Government and Community Relations
2015 myresearch Science Internship Program: Applied Medicine Civic Education Office of Government and Community Relations Harguneet Singh Science Internship Program: Applied Medicine Comparisons of Outcomes
Prostate Cancer UK s Best Practice Pathway
Prostate Cancer UK s Best Practice Pathway TREATMENT Updated August 2018 To be updated in vember Active surveillance What is the patient s stage of disease? Low risk localised PSA < 10 ng/ml and Gleason
First Year Annual Report Organisation of Services and Analysis of Existing Clinical Data
First Year Annual Report Organisation of Services and Analysis of Existing Clinical Data 1 NPCA Annual Report 2014 National Prostate Cancer Audit First Year Annual Report Organisation of Services and Analysis
Community care of Prostate Cancer. Shaun Costello Southern Cancer Network
Community care of Prostate Cancer Shaun Costello Southern Cancer Network Introduction Why is GP follow up of prostate cancer important 4Years In Waikato Faster Cancer Treatment Reporting against the 3
Prostate Cancer Screening Where are we? Prof. Bob Steele Professor of Surgery, University of Dundee Independent Chair, UK NSC
Prostate Cancer Screening Where are we? Prof. Bob Steele Professor of Surgery, University of Dundee Independent Chair, UK NSC 1990 Screening The detection of disease in asymptomatic people in order to
Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline Very Low-/Low-Risk Disease
Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline Very Low-/Low-Risk Disease Jeffrey A. Cadeddu, MD Professor, Department of Urology UT Southwestern Medical Center Vice-Chair, AUA/ASTRO/SUO
Management of castration resistant prostate cancer after first line hormonal therapy fails
Management of castration resistant prostate cancer after first line hormonal therapy fails Simon Crabb Senior Lecturer in Medical Oncology University of Southampton WHAT ARE THE AIMS OF TREATMENT? Cure?