Ouderen en kanker in Limburg

Size: px
Start display at page:

Download "Ouderen en kanker in Limburg"

Transcription

1 Ouderen en kanker in Limburg Frank Buntinx, Laura Deckx, Marjan Van den Akker Gerionne Analysis of the RNH and Intego databases: prevalent and subsequent co-morbidity in cancer and non-cancer. KLIMOP: a cohort study on cancer in older cancer. 1

2 Co-morbidity Co-morbidity in cancer and non-cancer RNH: GP-based database. serious morbidity of , 69 GPs in Limburg. Included: all cancer cases diagnosed between , all skin cancers excluded. Prevalent co-morbidity: cross-sectional design. Subsequent morbidity: (retrospective) cohort design, FU=6 months to 5 years after diagnosis cancer, non-cancer, matched on age, sex and practice. If applicable, the last three months before death were excluded. 2

3 Pre-existing (Men) 40 Number of chronic diseases at time of cancer diagnosis or reference date Men 60 years Male cancer Male non-cancer Pre-existing (Women) 40 Number of chronic diseases at time of cancer diagnosis or reference date Women 60 years Female cancer Female non-cancer 3

4 Pre-existing (men) - categories Pre-existing chronic diseases (men) Cardiovascular diseases Endocrine diseases Locomotor impairment Respiratory diseases Urogenital diseases Sensory diseases Psychological disorders Skin diseases Neurological - Disability Neurological - Pain Prevalence (per 1000) Non-cancer (n=5727) Cancer (n=1997) Subsequent (men) - categories Subsequent chronic diseases (men) Cardiovascular diseases Endocrine diseases Respiratory diseases Locomotor impairment Psychological disorders Urogenital diseases Sensory diseases Neurological - Disability Skin diseases Neurological - Pain 0,0 10,0 20,0 30,0 40,0 50,0 Incidence (per 1000 person years at risk) Non-cancer (n=5727) Cancer (n=1997) 4

5 Subsequent (men) - CVD Subsequent cardiovascular diseases (men) Heart failure Stroke/cerebrovascular accident Ischemic heart disease without angina Ischemic heart disease with angina Peripheral vascular disease Acute myocardial infarction Pulmonary embolism + thrombosis Atherosclerosis Hypertension complicated Pulmonary heart disease 0,0 10,0 20,0 30,0 40,0 50,0 Incidence (per 1000 person years at risk) Non-cancer Cancer Subsequent (men) 10 most common diseases 10 most common subsequent diseases (men) Diabetes mellitus Chronic obstructive pulmonary disease Heart failure Stroke/cerebrovascular accident Ischemic heart disease without angina Ischemic heart disease with angina Peripheral vascular disease Acute myocardial infarction Dementia Benign prostatic hypertrophy 0,0 10,0 20,0 30,0 40,0 50,0 Incidence (per 1000 person years at risk) Non-cancer Cancer 5

6 Subsequent (women) - CVD Subsequent cardiovascular diseases (women) Stroke/cerebrovascular accident Heart failure Ischemic heart disease without angina Ischemic heart disease with angina Acute myocardial infarction Peripheral vascular disease Hypertension complicated Pulmonary embolism + thrombosis Atherosclerosis Pulmonary heart disease 0,0 10,0 20,0 30,0 40,0 50,0 Incidence (per 1000 person years at risk) Non-cancer Cancer KLIMOP What is the influence of a cancer diagnosis, ageing and the interaction between them on general wellbeing of older? 6

7 Influence of cancer diagnosis, ageing & their interaction on general wellbeing Wellbeing: Co-morbidity ADL, IADL, cognition, depression, Quality of life Loneliness & social network Ageing: Age (years)? Frailty? Telomere length? Immunological ageing? Design Young cancer (50-69 years) Primary diagnosis of breast, lung, prostate or gastro-intestinal cancer Older cancer ( 70 years) Primary diagnosis of breast, lung, prostate or gastro-intestinal cancer Older without any previous cancer diagnosis ( 70 jaar) Ageing Cancer 7

8 Older cancer ( 70 y) Younger cancer (50 69 y) 1 year 2 years Older noncancer ( 70 y) Baseline 6 months Carers Interview Info from medical files 2 samples of cheek mucosa (questionnaire carers) KLIMOP: inclusion Baseline 6 months 1 year Younger cancer (50 69 years) Older cancer ( 70 years) Older non-cancer ( 70 years) Totaal Aim: 2 x 375 per group 8

9 Baseline Young cancer (50 69 y) Older cancer ( 70 y) Older noncancer ( 70 y) Age(mean, SD) (5.41) (4.95) (5.44) Gender: - male 38 (28%) 30 (38%) 50 (38%) - female 99 (72%) 48 (62%) 80 (62%) Global Qol (mean, SD) (19.18) (23.39) (19.26) ADL: - Completely independent 72 (52%) 35 (47%) 37 (32%) - Reasonably independent 63 (46%) 32 (43%) 67 (57%) - Some aid necessary 1 (1%) 5 (7%) 10 (9%) - Serious need for help 0 3 (4%) 3 (3%) - Completely dependent Total Baseline Young cancer (50 69 y) Older cancer ( 70 y) Older non-cancer ( 70 y) IADL: - Independent 113 (83%) 48 (62%) 59 (45%) - Limited in 1 or more domains GDS (18%) 30 (38%) 71 (54%) - Normal 113 (82%) 54 (69%) 101 (78%) - Depressive feelings 24 (18%) 24 (31%) 29 (22%) MMSE: -Normal 128 (94%) 66 (85%) 110 (85%) -Impaired 8 (6%) 12 (15%) 19 (15%) Totaal IADL: women (score between 0 8) IADL: men (score between 0 6, extra question on reparations added) GDS-15: 0-4 = normal, 5 depressive feelings MMSE: normal (30 25), impaired( 24) 9

10 Loneliness *: loneliness scale of De Jong-Gierveld most lonely were slightly lonely (only 8 scored > 8/11) Significant positive relation with QoL in both groups of cancer Significant relation with functional status (limited in > 2 domains): significant in older cancer only: OR= 4,3 (1,3-13,7) Relation with living situation (with others alone) not significant Baseline Depression ~ Fatigue* Normal Depression ( 5) T-test N Mean (SD) N Mean (SD) P-value Younger cancer Fatigue (24.72) (31.32) 0.01 Older cancer Fatigue (25.33) (28.93) 0.00 Older non-cancer Fatigue (21.29) (29.01) 0.00 * Fatigue is measured with the EORTC QLQ-C30 subscale. A higher score means more (max = 100) 10

11 Global Quality of life: Baseline ~ 6 months Worsening (>10%) No change Improvement (>10%) Younger cancer QoL: 22 (36%) 12 (20%) 27 (44%) Older cancer QoL: 14 (52%) 6 (22%) 7 (26%) Older non-cancer QoL: 17 (23%) 30 (41%) 27 (36%) Depression: no significant differences Cognition: no significant differences n=165 Fatigue: Baseline ~ 6 months Worsening (>10%) No change Improvement (>10%) Younger cancer Fatigue 34 (56%) 18 (30%) 9 (15%) Older cancer Fatigue 10 (37%) 14 (52%) 3 (11%) Older non-cancer Fatigue 23 (31%) 28 (38%) 23 (31%) P=0.01 (worsening no worsening) n =

12 Deckx L, Van Abbema D, Nelissen K, Daniels L, Stinissen P, Bulens P, Linsen L, Rummens JL, Van den Berkmortel F, Robaeys G, De Jonge E, Houben B, Pat K, Walgraeve D, Spaas L, Verheezen J, Verniest T, Goegebuer A, Wildiers H, Tjan-Heijnen V, Buntinx F, Van den Akker M, Research group on older cancer. Study protocol of KLIMOP: a cohort study on the wellbeing of older cancer in Belgium and the Netherlands. BMC Publ Health 2011; 11: 825 contact: laura.deckx@med.kuleuven.be - doris.van.abbema@mumc.nl 12

The utilization of formal and informal home care by older patients with cancer: a Belgian cohort study with two control groups

The utilization of formal and informal home care by older patients with cancer: a Belgian cohort study with two control groups Baitar et al. BMC Health Services Research (2017) 17:644 DOI 10.1186/s12913-017-2594-4 RESEARCH ARTICLE Open Access The utilization of formal and informal home care by older patients with cancer: a Belgian

More information

Deckx et al. BMC Geriatrics (2015) 15:79 DOI /s

Deckx et al. BMC Geriatrics (2015) 15:79 DOI /s Deckx et al. BMC Geriatrics (2015) 15:79 DOI 10.1186/s12877-015-0071-7 RESEARCH ARTICLE A cohort study on the evolution of psychosocial problems in older patients with breast or colorectal cancer: comparison

More information

Comorbidity patterns in cancer survivors in the 21st century. Marjan van den Akker

Comorbidity patterns in cancer survivors in the 21st century. Marjan van den Akker Comorbidity patterns in cancer survivors in the 21st century Marjan van den Akker Background Comorbidity & multimorbidity concepts relevance methodological challenges Comorbidity in cancer patients somatic

More information

NAME: DATE: SCHOOL/ORGANISATION:

NAME: DATE: SCHOOL/ORGANISATION: HEALTH AND FITNESS NAME: DATE: SCHOOL/ORGANISATION: INSTRUCTIONS 1. Make sure you read the bold text in boxes throughout the worksheet as they contain important information. These boxes contain instructions

More information

FY 2011 WISEWOMAN Approved ICD-9 Code List

FY 2011 WISEWOMAN Approved ICD-9 Code List 243 Congenital hypothyroidism 245.0 Thyroiditis; Acute thyroiditis 245.1 Thyroiditis; Subacute thyroiditis 245.2 Thyroiditis; Chronic lymphocytic thyroiditis 245.3 Thyroiditis; Chronic fibrous thyroiditis

More information

Comorbidities and cancer Applications to non small cell lung cancer

Comorbidities and cancer Applications to non small cell lung cancer Comorbidities and cancer Applications to non small cell lung cancer Pr A. Vergnenègre Dr H. Le Caer CHU Limoges CH Draguignan 1 Comorbidities and cancer Why? 2 Epidemiology elderly among lung cancer 2010-2014

More information

Lauren Griffith McMaster University

Lauren Griffith McMaster University The Impact of Chronic Condition List on Prevalence and the Relationship between MCCs and Disability, Social Participation, and Self- Rated Health: Data from the Canadian Longitudinal Study on Aging Lauren

More information

The relation between depression, coping and health locus of control: differences between older and younger patients, with and without cancer

The relation between depression, coping and health locus of control: differences between older and younger patients, with and without cancer Psycho-Oncology Psycho-Oncology (2015) Published online in Wiley Online Library (wileyonlinelibrary.com)..3748 The relation between depression, coping and health locus of control: differences between older

More information

Pharmaco-epidemiological outcome research

Pharmaco-epidemiological outcome research Pharmaco-epidemiological outcome research Using the PHARMO-Eindhoven Cancer Registry linkage Lonneke van de Poll-Franse Professor of Cancer Epidemiology and Survivorship, Tilburg University & Head department

More information

NurseAchieve. CHAPTERS INCLUDED IN THE NURSEACHIEVE COMPREHENSIVE NCLEX REVIEW NURSING SKILLS AND FUNDAMENTALS:

NurseAchieve.   CHAPTERS INCLUDED IN THE NURSEACHIEVE COMPREHENSIVE NCLEX REVIEW NURSING SKILLS AND FUNDAMENTALS: NurseAchieve www.nurseachieve.com CHAPTERS INCLUDED IN THE NURSEACHIEVE COMPREHENSIVE NCLEX REVIEW NCLEX TEST STRATEGIES: NCLEX EXAM OVERVIEW TEST TAKING STRATEGIES NURSING SKILLS AND FUNDAMENTALS: ADMINISTRATION

More information

Supplementary Online Content

Supplementary Online Content Supplementary Online Content Dharmarajan K, Wang Y, Lin Z, et al. Association of changing hospital readmission rates with mortality rates after hospital discharge. JAMA. doi:10.1001/jama.2017.8444 etable

More information

A Closer Look at Leading Causes of Death in Guilford County

A Closer Look at Leading Causes of Death in Guilford County 2015 GCDHHS Division of Public Health Data Brief A Closer Look at Leading Causes of Death in Guilford County Highlights Heart disease mortality rates declined 43% from 244.8 deaths per 100,000 in 1995

More information

Supplementary Online Content

Supplementary Online Content Supplementary Online Content Steinhubl SR, Waalen J, Edwards AM, et al. Effect of a home-based wearable continuous electrocardiographic monitoring patch on detection of undiagnosed atrial fibrillation

More information

S2 File. Clinical Classifications Software (CCS). The CCS is a

S2 File. Clinical Classifications Software (CCS). The CCS is a S2 File. Clinical Classifications Software (CCS). The CCS is a diagnosis categorization scheme based on the ICD-9-CM that aggregates all diagnosis codes into 262 mutually exclusive, clinically homogeneous

More information

Table E1. Standardized Mortality Ratios for Total and Specific Causes of Death Parameter Radiologists Psychiatrists No. of Deaths

Table E1. Standardized Mortality Ratios for Total and Specific Causes of Death Parameter Radiologists Psychiatrists No. of Deaths RSNA, 2016 10.1148/radiol.2016152472 Table E1. Standardized Mortality Ratios for Total and Specific Causes of Death Parameter Radiologists Psychiatrists No. of Deaths Observed/Expected No. of Deaths Observed/Expected

More information

Process Measure: Screening for Adult Obstructive Sleep Apnea

Process Measure: Screening for Adult Obstructive Sleep Apnea Process Measure: Screening for Adult Obstructive Sleep Apnea Measure Description Description Type of Measure All patients aged 18 years and older at high risk for obstructive sleep apnea (OSA) with documentation

More information

Frailty Assessment: Simplifying the Complex

Frailty Assessment: Simplifying the Complex Frailty Assessment: Simplifying the Complex Natalie Sanders, DO Internal Medicine, Geriatrics Rocky Mountain Geriatrics Conference 2017 U N I V E R S I T Y O F U T A H H E A L T H, 2 0 1 7 OBJECTIVES Define

More information

MOS SF-36 health survey (Ware &

MOS SF-36 health survey (Ware & Biomedical and Physical Functioning General Health Height Weight Waist Circumfernece % Body Fat Tanita scale BMI Self-rated Health - overall clinical protocol Self-rated Health - rel. to age clinical protocol

More information

Unintentional Weight Loss. Prof. G. Zuliani

Unintentional Weight Loss. Prof. G. Zuliani Unintentional Weight Loss Prof. G. Zuliani Is weight loss clinically important? Definition Clinically important weight loss can be defined as loss of >5 kg, or >5% of usual weight over a period of 3 months,

More information

Suicides increased in 2014

Suicides increased in 2014 Causes of death 2014 23 May, 2016 Suicides increased in 2014 Diseases of the circulatory system accounted for 30.7% of the deaths recorded in 2014, 2.4% more than in the previous year. The average age

More information

5.2 Main causes of death Brighton & Hove JSNA 2013

5.2 Main causes of death Brighton & Hove JSNA 2013 Why is this issue important? We need to know how many people are born and die each year and the main causes of their deaths in order to have well-functioning health s. 1 Key outcomes Mortality rate from

More information

The links between physical health in mental health

The links between physical health in mental health The links between physical health in mental health A holistic approach to managing mental and physical health is needed. Physical and mental health are inextricably linked 1 What is the problem? It is

More information

Professor Karl Claxton, Centre for Health Economics, University of York

Professor Karl Claxton, Centre for Health Economics, University of York Welcome to the InstEAD Annual Lecture 2014 Professor Karl Claxton, Centre for Health Economics, University of York Health (and ethics) Needs Economics: Which Health Technologies, at What Price and for

More information

Transfusion triggers in acute coronary syndromes: The MINT trial

Transfusion triggers in acute coronary syndromes: The MINT trial Transfusion triggers in acute coronary syndromes: The MINT trial Paul Hébert, MD MHSc(Epid) Physician-in-Chief, CHUM Professor, University of Montreal Objectives Review evidence on transfusion triggers

More information

WASHINGTON UNIVERSITY SCHOOL OF MEDICINE. Cranial Health History Form

WASHINGTON UNIVERSITY SCHOOL OF MEDICINE. Cranial Health History Form WASHINGTON UNIVERSITY SCHOOL OF MEDICINE Cranial Health History Form Welcome to the Neurosurgery Department at Washington University. To help us treat you, please fill this form out completely. Your Name:

More information

SENIOR PDHPE HEALTH PRIORITIES IN AUSTRALIA INTRODUCTORY NOTES NAME SCHOOL / ORGANISATION DATE

SENIOR PDHPE HEALTH PRIORITIES IN AUSTRALIA INTRODUCTORY NOTES NAME SCHOOL / ORGANISATION DATE SENIOR PDHPE HEALTH PRIORITIES IN AUSTRALIA NAME SCHOOL / ORGANISATION DATE INTRODUCTORY NOTES AUSTRALIA S HEALTH PRIORITIES The current AIHW report, Australia s Health, identifies nine major categories

More information

COGNOS. Care for people with Cognitive dysfunction A National Observational Study. Professor Dr Jan De Lepeleire COGNOS members

COGNOS. Care for people with Cognitive dysfunction A National Observational Study. Professor Dr Jan De Lepeleire COGNOS members COGNOS Care for people with Cognitive dysfunction A National Observational Study Professor Dr Jan De Lepeleire COGNOS members Luxembourg Alzheimer Europe 2010 The Careplan in Belgium Requirements for reimbursement

More information

Epidemiology and Impact of A Little Bit of Afib" Margot E. Vloka, MD, FACC, FHRS St. Alphonsus Regional Medical Center Heart Institute Boise, Idaho

Epidemiology and Impact of A Little Bit of Afib Margot E. Vloka, MD, FACC, FHRS St. Alphonsus Regional Medical Center Heart Institute Boise, Idaho Epidemiology and Impact of A Little Bit of Afib" Margot E. Vloka, MD, FACC, FHRS St. Alphonsus Regional Medical Center Heart Institute Boise, Idaho Disclosures: Medtronic Biotronic AtriCure What is Atrial

More information

University of Groningen. Leven na een beroerte Loor, Henriëtte Ina

University of Groningen. Leven na een beroerte Loor, Henriëtte Ina University of Groningen Leven na een beroerte Loor, Henriëtte Ina IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document

More information

VENOUS THROMBOEMBOLISM AND CORONARY ARTERY DISEASE: IS THERE A LINK?

VENOUS THROMBOEMBOLISM AND CORONARY ARTERY DISEASE: IS THERE A LINK? VENOUS THROMBOEMBOLISM AND CORONARY ARTERY DISEASE: IS THERE A LINK? Ayman El-Menyar (1), MD, Hassan Al-Thani (2),MD (1)Clinical Research Consultant, (2) Head of Vascular Surgery, Hamad General Hospital

More information

UNDERWRITING GUIDELINES. Individual Insurance

UNDERWRITING GUIDELINES. Individual Insurance UNDERWRITING GUIDELINES Individual Insurance TABLE OF CONTENTS About this guide... 4 Medical conditions Asthma...5 Auricular fibrillation...5 Autism...5 Bariatric surgery...5 Barrett s esophagus...5 Cancer

More information

Antithrombotic therapy in patients with transient ischemic attack / stroke (acute phase <48h)

Antithrombotic therapy in patients with transient ischemic attack / stroke (acute phase <48h) Antithrombotic therapy in patients with transient ischemic attack / stroke (acute phase

More information

Lipids Testing

Lipids Testing Previously Listed as Edit 12 190.23 - Lipids Testing Lipoproteins are a class of heterogeneous particles of varying sizes and densities containing lipid and protein. These lipoproteins include cholesterol

More information

Blood transfusions in ICU: double-edged sword. Paul Hébert, MD MHSc(Epid) Physician-in-Chief, CHUM Professor, University of Montreal

Blood transfusions in ICU: double-edged sword. Paul Hébert, MD MHSc(Epid) Physician-in-Chief, CHUM Professor, University of Montreal Blood transfusions in ICU: double-edged sword Paul Hébert, MD MHSc(Epid) Physician-in-Chief, CHUM Professor, University of Montreal Canadian Critical Care Trials Group Collaborating for Impact Leading

More information

SENIOR PDHPE WORKSHEET Health Priorities in Australia

SENIOR PDHPE WORKSHEET Health Priorities in Australia SENIOR PDHPE WORKSHEET Health Priorities in Australia NAME ORGANISATION DATE INSTRUCTIONS 1. Make sure you read the bold text in boxes throughout the worksheet as they contain important information These

More information

ATTENTION-DEFICIT/HYPERACTIVITY DISORDER, PHYSICAL HEALTH, AND LIFESTYLE IN OLDER ADULTS

ATTENTION-DEFICIT/HYPERACTIVITY DISORDER, PHYSICAL HEALTH, AND LIFESTYLE IN OLDER ADULTS CHAPTER 5 ATTENTION-DEFICIT/HYPERACTIVITY DISORDER, PHYSICAL HEALTH, AND LIFESTYLE IN OLDER ADULTS J. AM. GERIATR. SOC. 2013;61(6):882 887 DOI: 10.1111/JGS.12261 61 ATTENTION-DEFICIT/HYPERACTIVITY DISORDER,

More information

SUPPLEMENTARY MATERIAL

SUPPLEMENTARY MATERIAL SUPPLEMENTARY MATERIAL Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records Riccardo Miotto 1,2, Li Li 1,2, Brian A. Kidd 1,2, and Joel T. Dudley

More information

Information Management. A System We Can Count On. Chronic Conditions. in the Central East LHIN

Information Management. A System We Can Count On. Chronic Conditions. in the Central East LHIN Information Management A System We Can Count On Chronic Conditions in the Central East LHIN Health System Intelligence Project October 2007 Table of Contents About HSIP..................................ii

More information

Are the ESMO guidelines adapted to the elderly? D. Schrijvers, MD, PhD Ziekenhuisnetwerk Antwerpen(ZNA)-Middelheim Antwerp Belgium

Are the ESMO guidelines adapted to the elderly? D. Schrijvers, MD, PhD Ziekenhuisnetwerk Antwerpen(ZNA)-Middelheim Antwerp Belgium Are the ESMO guidelines adapted to the elderly? D. Schrijvers, MD, PhD Ziekenhuisnetwerk Antwerpen(ZNA)-Middelheim Antwerp Belgium Clinical practice guidelines Definition > Systemically developed statements

More information

Physiological disorders

Physiological disorders Physiological disorders Overview of major causes and signs and symptoms Learning Aim A: Tuesday 7 th February 2017 Grading Criteria Causative factors in physiological disorders Aetiology is the medical

More information

Community Based Occupational Therapy for people with dementia (COTiD) and their caregiver: evidence for applicability in Italy

Community Based Occupational Therapy for people with dementia (COTiD) and their caregiver: evidence for applicability in Italy Community Based Occupational Therapy for people with dementia (COTiD) and their caregiver: evidence for applicability in Italy Andrea Fabbo Cognitive Disorders and Dementia Unit, Local Health Autorithy

More information

The following list provides the learning objectives that will be covered in the lectures, and tutorials of each week:

The following list provides the learning objectives that will be covered in the lectures, and tutorials of each week: Course Code Course Title ECTS Credits MED-304 Pathology I 6 School Semester Prerequisites Medical School Fall (Semester 5) None Type of Course Field Language of Instruction Required Medicine English Level

More information

A Comparative Analysisof Male versus Female Breast Cancer in the ACS NSQIP Database

A Comparative Analysisof Male versus Female Breast Cancer in the ACS NSQIP Database A Comparative Analysisof Male versus Female Breast Cancer in the ACS NSQIP Database Lindsay Petersen, MD Rush University Medical Center Chicago, IL I would like to recognize my coauthors: Andrea Madrigrano,

More information

ICD-10 Physician Education. General Surgery

ICD-10 Physician Education. General Surgery ICD-10 Physician Education General Surgery 1 Training Objectives ICD-9 to ICD-10 Comparison Documentation Tips Additional Educational Opportunities Questions 2 ICD-9 to ICD-10 Comparison Code Structure

More information

Alliance A Symptomatic brain radionecrosis after receiving radiosurgery for

Alliance A Symptomatic brain radionecrosis after receiving radiosurgery for RANDOMIZED PHASE II STUDY: CORTICOSTEROIDS + BEVACIZUMAB VS. CORTICOSTEROIDS + PLACEBO (BEST) FOR RADIONECROSIS AFTER RADIOSURGERY FOR BRAIN METASTASES Pre-registration Eligibility Criteria Required Initial

More information

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/36088 holds various files of this Leiden University dissertation. Author: Houwelingen, Anne Henriëtte van Title: A proactive approach to complex problems

More information

Comorbidity or medical history Existing diagnoses between 1 January 2007 and 31 December 2011 AF management care AF symptoms Tachycardia

Comorbidity or medical history Existing diagnoses between 1 January 2007 and 31 December 2011 AF management care AF symptoms Tachycardia Supplementary Table S1 International Classification of Disease 10 (ICD-10) codes Comorbidity or medical history Existing diagnoses between 1 January 2007 and 31 December 2011 AF management care I48 AF

More information

RALP Registration Form (new registration)

RALP Registration Form (new registration) RALP Registration Form (new registration) RALP registration form new registration v2.0 1 RALP registration form new registration All fields are required, except those marked with an asterisk (*) Variables

More information

Autism CRC Presentation - Longitudinal Study of Adults - 3DN Opportunities for Collaboration

Autism CRC Presentation - Longitudinal Study of Adults - 3DN Opportunities for Collaboration Autism CRC Presentation - Longitudinal Study of Adults - 3DN Opportunities for Collaboration Julian Trollor & Kitty Foley School of Psychiatry, UNSW Australia j.trollor@unsw.edu.au k.foley@unsw.edu.au

More information

CUMULATIVE ILLNESS RATING SCALE (CIRS)

CUMULATIVE ILLNESS RATING SCALE (CIRS) CUMULATIVE ILLNESS RATING SCALE (CIRS) The CIRS used in this protocol is designed to provide an assessment of recurrent or ongoing chronic comorbid conditions, classified by 14 organ systems. Using the

More information

Supplement materials:

Supplement materials: Supplement materials: Table S1: ICD-9 codes used to define prevalent comorbid conditions and incident conditions Comorbid condition ICD-9 code Hypertension 401-405 Diabetes mellitus 250.x Myocardial infarction

More information

Fracture REduction Evaluation (FREE) Study

Fracture REduction Evaluation (FREE) Study Fracture REduction Evaluation (FREE) Study Efficacy and Safety of Balloon Kyphoplasty Compared with Non-surgical Care for Vertebral Compression Fracture (FREE): A Randomised Controlled Trial Wardlaw Lancet

More information

Division of Pulmonary, Critical Care, and Sleep Medicine, Jacksonville, FL. Department of Internal Medicine, Wichita, KS

Division of Pulmonary, Critical Care, and Sleep Medicine, Jacksonville, FL. Department of Internal Medicine, Wichita, KS in Patients with Respiratory Disease Furqan Shoaib Siddiqi, M.D. 1, Said Chaaban, M.D. 2, Erin Petersen, M.S.N., A.P.R.N. 3, K James Kallail, Ph.D. 2, Mary Hope, B.H.S., A.R.T., R.R.T., C.P.F.T. 3, Daniel

More information

JAMA, January 11, 2012 Vol 307, No. 2

JAMA, January 11, 2012 Vol 307, No. 2 JAMA, January 11, 2012 Vol 307, No. 2 Dementia is associated with increased rates and often poorer outcomes of hospitalization Worsening cognitive status Adequate chronic disease management is more difficult

More information

ESM1 for Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study

ESM1 for Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study ESM1 for Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study Statistical modelling details We used Cox proportional-hazards

More information

Following the health of half a million participants

Following the health of half a million participants Following the health of half a million participants Cathie Sudlow UK Biobank Scientific Conference London, June 2018 Follow-up of participants in very large prospective cohorts Aim: identify a wide range

More information

As the proportion of the elderly in the

As the proportion of the elderly in the CANCER When the cancer patient is elderly, how do you weigh the risks of surgery? Marguerite Palisoul, MD Dr. Palisoul is Fellow in the Department of Obstetrics and Gynecology, Division of Gynecologic

More information

Royal College of Psychiatrists Consultation Response

Royal College of Psychiatrists Consultation Response Royal College of Psychiatrists Consultation Response DATE: 10 March 2017 RESPONSE OF: RESPONSE TO: THE ROYAL COLLEGE OF PSYCHIATRISTS in WALES HSCS Committee, Isolation and Loneliness The Royal College

More information

Introduction to the Singapore Chinese Health Study (SCHS)

Introduction to the Singapore Chinese Health Study (SCHS) Introduction to the Singapore Chinese Health Study (SCHS) The Singapore Chinese Health Study is a large-scale research study in the National University of Singapore (Current PI: Prof Woon-Puay Koh), and

More information

Case 1 Metastatic Pancreatic Adenocarcinoma: What Therapy Should I Select First?

Case 1 Metastatic Pancreatic Adenocarcinoma: What Therapy Should I Select First? Case 1 Metastatic Pancreatic Adenocarcinoma: What Therapy Should I Select First? Marc Peeters, MD, PhD Head of the Oncology Department Antwerp University Hospital Antwerp, Belgium marc.peeters@uza.be 71-year-old

More information

Ulster, Ireland. Submitted: 21 June 2009; Revised: 24 January 2010; Published: 13 September 2010 Petrazzuoli F, Soler JK, Buono N, Dobbs F

Ulster, Ireland. Submitted: 21 June 2009; Revised: 24 January 2010; Published: 13 September 2010 Petrazzuoli F, Soler JK, Buono N, Dobbs F O R I G I N A L R E S E A R C H Quality of care for hypertensive patients with type 2 diabetes in a rural area of Southern Italy: is the recording of patient data and the achievement of quality indicators

More information

JUSTUS WARREN TASK FORCE MEETING DECEMBER 05, 2012

JUSTUS WARREN TASK FORCE MEETING DECEMBER 05, 2012 SAMUEL TCHWENKO, MD, MPH Epidemiologist, Heart Disease & Stroke Prevention Branch Chronic Disease & Injury Section; Division of Public Health NC Department of Health & Human Services JUSTUS WARREN TASK

More information

Chronic Obstructive Pulmonary Disease (COPD) Comorbidities Network

Chronic Obstructive Pulmonary Disease (COPD) Comorbidities Network Chronic Obstructive Pulmonary Disease (COPD) Comorbidities Network Miguel J. Divo MD, Ciro Casanova MD, Jose M. Marin MD, Victor M. Pinto-Plata MD, Juan P. de-torres MD, Javier Zulueta MD, Carlos Cabrera

More information

CONTRIBUTING FACTORS FOR STROKE:

CONTRIBUTING FACTORS FOR STROKE: CONTRIBUTING FACTORS FOR STROKE: DIABETES AND OBESITY Fruzsina K. Johnson, MD Professor of Preclinical Sciences William Carey University College of Osteopathic Medicine LEARNING OBJECTIVES The learner

More information

Blueprint Schwerpunktprüfung Geriatrie (Version 2011) Medical Content Category

Blueprint Schwerpunktprüfung Geriatrie (Version 2011) Medical Content Category Blueprint Schwerpunktprüfung Geriatrie (Version 2011) A A1 A2 Gerontology Demography and epidemiology Psychology and sociology of aging Demographic development in Switzerland, Europe and USA Life expectancy

More information

SUPPLEMENTAL MATERIAL

SUPPLEMENTAL MATERIAL SUPPLEMENTAL MATERIAL Cognitive impairment evaluated with Vascular Cognitive Impairment Harmonization Standards in a multicenter prospective stroke cohort in Korea Supplemental Methods Participants From

More information

HOME DIALYSIS Pre-Assessment Form

HOME DIALYSIS Pre-Assessment Form Date of Assessment: Cell Phone: Email: Work phone: CONTACT Person: Renal Diagnosis: Transplant Status: Medical History: Dialysis History: Current Medications: (attach copy of medication list if posssible)

More information

Raluca Pavaloiu et al. - Clinical, Epidemiological and Etiopathogenic Study of Ischemic Stroke

Raluca Pavaloiu et al. - Clinical, Epidemiological and Etiopathogenic Study of Ischemic Stroke Original Paper Clinical, Epidemiological and Etiopathogenic Study of Ischemic Stroke RALUCA PAVALOIU 1, L. MOGOANTA 2 1 Department of Neurology, Hospital of Neuropsychiatry Craiova, Romania 2 Department

More information

Heart Failure and COPD: Common Partners, Common Problems. Nat Hawkins Liverpool Heart and Chest Hospital

Heart Failure and COPD: Common Partners, Common Problems. Nat Hawkins Liverpool Heart and Chest Hospital Heart Failure and COPD: Common Partners, Common Problems Nat Hawkins Liverpool Heart and Chest Hospital Disclosures: No conflicts of interest Common partners, common problems COPD in HF common partners

More information

Asthma J45.20 Mild, uncomplicated J45.21 Mild, with (acute) exacerbation J45.22 Mild, with status asthmaticus

Asthma J45.20 Mild, uncomplicated J45.21 Mild, with (acute) exacerbation J45.22 Mild, with status asthmaticus A Fib & Flutter I48.0 Paroxysmal atrial fibrillation I48.1 Persistent atrial fibrillation I48.2 Chronic atrial fibrillation I48.3 Typical atrial flutter Asthma J45.20 Mild, uncomplicated J45.21 Mild, with

More information

Quality of Life after. A Critical Illness: A review of the literature

Quality of Life after. A Critical Illness: A review of the literature 1 Quality of Life after A Critical Illness: A review of the literature 1998 2003 by Harriet Adamson BN MAdEd A Thesis submitted in fulfillment of the requirements for the degree Master of Nursing (Honours)

More information

DIABETES MORTALITY IN NOVA SCOTIA FROM 1998 TO 2005: A DESCRIPTIVE ANALYSIS USING BOTH UNDERLYING AND MULTIPLE CAUSES OF DEATH

DIABETES MORTALITY IN NOVA SCOTIA FROM 1998 TO 2005: A DESCRIPTIVE ANALYSIS USING BOTH UNDERLYING AND MULTIPLE CAUSES OF DEATH DIABETES MORTALITY IN NOVA SCOTIA FROM 1998 TO 2005: A DESCRIPTIVE ANALYSIS USING BOTH UNDERLYING AND MULTIPLE CAUSES OF DEATH Alison Zwaagstra Health Information Analyst Network for End of Life Studies

More information

Lnformation Coverage Guidance

Lnformation Coverage Guidance Lnformation Coverage Guidance Coverage Indications, Limitations, and/or Medical Necessity Abstract: B-type natriuretic peptide (BNP) is a cardiac neurohormone produced mainly in the left ventricle. It

More information

Patient Name Date of Birth Age. Other phone ( ) . Other

Patient Name Date of Birth Age. Other phone ( )  . Other GASTROINTESTINAL & MINIMALLY INVASIVE SURGERY HEALTH HISTORY QUESTIONNAIRE Date Patient Name _ Date of Birth Age Daytime phone ( ) Other phone ( ) Email How did you hear about us? My doctor Yellow pages

More information

Heart disease remains the leading cause of morbidity and mortality in industrialized nations. It accounts for nearly 40% of all deaths in the United

Heart disease remains the leading cause of morbidity and mortality in industrialized nations. It accounts for nearly 40% of all deaths in the United Heart disease remains the leading cause of morbidity and mortality in industrialized nations. It accounts for nearly 40% of all deaths in the United States, totaling about 750,000 individuals annually

More information

Student Outline. Improving Transportation Safety: Commercial Driver Medical Examiner Training CHAPTER 1. General FMCSA Information

Student Outline. Improving Transportation Safety: Commercial Driver Medical Examiner Training CHAPTER 1. General FMCSA Information Student Outline CHAPTER 1 General FMCSA Information FMCSA Mission Statement / Dedicated to Safety / NRCME Important Definitions Regulations Vs. Medical Guidelines Privacy and the Medical Examination 13

More information

Full Novartis CTRD Results Template

Full Novartis CTRD Results Template Full Novartis CTRD Results Template Sponsor Novartis Generic Drug Name vildagliptin Therapeutic Area of Trial Type 2 diabetes Approved Indication Type 2 diabetes Protocol Number CLAF237A23138E1 Title A

More information

How a universal health system reduces inequalities: lessons from England

How a universal health system reduces inequalities: lessons from England How a universal health system reduces inequalities: lessons from England Appendix 1: Indicator Definitions Primary care supply Definition: Primary care supply is defined as the number of patients per full

More information

APPENDIX EXHIBITS. Appendix Exhibit A2: Patient Comorbidity Codes Used To Risk- Standardize Hospital Mortality and Readmission Rates page 10

APPENDIX EXHIBITS. Appendix Exhibit A2: Patient Comorbidity Codes Used To Risk- Standardize Hospital Mortality and Readmission Rates page 10 Ross JS, Bernheim SM, Lin Z, Drye EE, Chen J, Normand ST, et al. Based on key measures, care quality for Medicare enrollees at safety-net and non-safety-net hospitals was almost equal. Health Aff (Millwood).

More information

Why is co-morbidity important for cancer patients? Di Riley Associate Director Clinical Outcomes Programme

Why is co-morbidity important for cancer patients? Di Riley Associate Director Clinical Outcomes Programme Why is co-morbidity important for cancer patients? Di Riley Associate Director Clinical Outcomes Programme Co-morbidity in cancer Definition:- Co-morbidity is a disease or illness affecting a cancer patient

More information

Recent findings: Dementia Outcomes Measurement Suite

Recent findings: Dementia Outcomes Measurement Suite University of Wollongong Research Online Australian Health Services Research Institute Faculty of Business 008 Recent findings: Dementia Outcomes Measurement Suite Janet Sansoni University of Wollongong,

More information

10/8/2018. Lecture 9. Cardiovascular Health. Lecture Heart 2. Cardiovascular Health 3. Stroke 4. Contributing Factor

10/8/2018. Lecture 9. Cardiovascular Health. Lecture Heart 2. Cardiovascular Health 3. Stroke 4. Contributing Factor Lecture 9 Cardiovascular Health 1 Lecture 9 1. Heart 2. Cardiovascular Health 3. Stroke 4. Contributing Factor 1 The Heart Muscular Pump The Heart Receives blood low pressure then increases the pressure

More information

All Discovered Death Outcome Detail (Form 124/120)

All Discovered Death Outcome Detail (Form 124/120) This file includes all reported deaths regardless of consent. ID WHI Common ID Col#1 DEATHALL All Discovered Death Col#2 Any report of death, regardless of consent status. 0 No 106,931 66.1 1 Yes 54,877

More information

Questionnaire information Name of the questionnaire Questionario per l'informatore [Informant questionnaire]

Questionnaire information Name of the questionnaire Questionario per l'informatore [Informant questionnaire] (Informant). of the study Viale Regina Elena 99 00 Rome Italy Telephone +39 0 4990 408 409. of the questionnaire Questionario per l'informatore [Informant questionnaire]. /wave.. Questionnaire ID or year

More information

Joshua A. Beckman, MD. Brigham and Women s Hospital

Joshua A. Beckman, MD. Brigham and Women s Hospital Peripheral Vascular Disease: Overview, Peripheral Arterial Obstructive Disease, Carotid Artery Disease, and Renovascular Disease as a Surrogate for Coronary Artery Disease Joshua A. Beckman, MD Brigham

More information

Hu J, Gonsahn MD, Nerenz DR. Socioeconomic status and readmissions: evidence from an urban teaching hospital. Health Aff (Millwood). 2014;33(5).

Hu J, Gonsahn MD, Nerenz DR. Socioeconomic status and readmissions: evidence from an urban teaching hospital. Health Aff (Millwood). 2014;33(5). Appendix Definitions of Index Admission and Readmission Definitions of index admission and readmission follow CMS hospital-wide all-cause unplanned readmission (HWR) measure as far as data are available.

More information

Quality of prescribing in chronic kidney disease and type 2 diabetes Smits, Kirsten Petronella Juliana

Quality of prescribing in chronic kidney disease and type 2 diabetes Smits, Kirsten Petronella Juliana University of Groningen Quality of prescribing in chronic kidney disease and type 2 diabetes Smits, Kirsten Petronella Juliana IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's

More information

SURGICAL COMPLICATIONS OF CERVICAL SPONDYLOTIC MYELOPATHY

SURGICAL COMPLICATIONS OF CERVICAL SPONDYLOTIC MYELOPATHY OBJECTIVE SURGICAL COMPLICATIONS OF CERVICAL SPONDYLOTIC MYELOPATHY Matamalas A, Plano X, Pellisé F,García de Frutos A, Casamitjana J. Spine Unit. Hospital Vall d Hebrón. Barcelona To assess the rate of

More information

Fighting Polypharmacy - From Theory to Practice :

Fighting Polypharmacy - From Theory to Practice : Fighting Polypharmacy - From Theory to Practice : A Rational, Cost Effective Approach for Improving Drug Therapy in Disabled Elderly People Doron Garfinkel, M.D., Sara Zur-Gil, Elena Kundzinsh, M.D., Joshua

More information

Selected Overweight- and Obesity- Related Health Disorders

Selected Overweight- and Obesity- Related Health Disorders Selected Overweight- and Obesity- Related Health Disorders HIGHLIGHTS Obesity and overweight are predisposing factors for the development of type 2 diabetes mellitus, coronary heart disease, stroke, osteoarthritis

More information

Representation of Patients with Cardiovascular Disease in Pivotal Cancer. Clinical Trials

Representation of Patients with Cardiovascular Disease in Pivotal Cancer. Clinical Trials Representation of Patients with Cardiovascular Disease in Pivotal Cancer Clinical Trials Running Title: Bonsu & Charles et al.; Cardiovascular Patients in Cancer Trials Janice Bonsu, MPH 1* ; Lawrence

More information

Proposed approach to fill data gaps on selected chronic diseases: mental disorders and dementia/alzheimer s disease

Proposed approach to fill data gaps on selected chronic diseases: mental disorders and dementia/alzheimer s disease Proposed approach to fill data gaps on selected chronic diseases: mental disorders and dementia/alzheimer s disease OECD Health Data National Correspondents 8-9 October 2009 1 Background Broad approach

More information

Peel Health Facts. Population Projections 2004, Region of Peel and Municipalities

Peel Health Facts. Population Projections 2004, Region of Peel and Municipalities Peel Health Facts Population Population Projections 2004, Region of Peel and Municipalities Mississauga Brampton Caledon Peel Male 318,004 188,688 27,476 534,084 Female 326,991 191,315 27,524 545,922 Total

More information

Prevalence And Trends In Obesity Among Aged And Disabled U.S. Medicare Beneficiaries,

Prevalence And Trends In Obesity Among Aged And Disabled U.S. Medicare Beneficiaries, Trends Prevalence And Trends In Obesity Among Aged And Disabled U.S. Medicare Beneficiaries, 1997 2002 The rise in obesity among beneficiaries, along with expansions in treatment coverage, could greatly

More information

Oldham Exercise Referral Scheme

Oldham Exercise Referral Scheme OLDHAM COMMUNITY LEISURE Oldham Exercise Referral Scheme April 2015 Exercise Referral Scheme April 2015 From April 2015 Oldham Community will be changing the format of delivery of the Exercise Referral

More information

STEPHEN P. NONN OFFICE OF THE CORONER MADISON COUNTY, ILLINOIS 157 MAIN STREET SUITE 354 EDWARDSVILLE, IL

STEPHEN P. NONN OFFICE OF THE CORONER MADISON COUNTY, ILLINOIS 157 MAIN STREET SUITE 354 EDWARDSVILLE, IL MAIN OFFICE: (618) 692-7478 MORGUE: (618) 296-4525 FAX: (618) 692-6042 FAX: (618) 692-9304 STEPHEN P. NONN OFFICE OF THE CORONER MADISON COUNTY, ILLINOIS 157 MAIN STREET SUITE 354 EDWARDSVILLE, IL. 62025-1962

More information

4. Which survey program does your facility use to get your program designated by the state?

4. Which survey program does your facility use to get your program designated by the state? TRAUMA SURVEY Please complete one survey for each TCD designation you have in your facility. There would be a maximum of three surveys completed if your facility was designated as a trauma, stroke and

More information

USMLE STEP 2 CK REVIEW STUDY GUIDE

USMLE STEP 2 CK REVIEW STUDY GUIDE USMLE STEP 2 CK REVIEW STUDY GUIDE 2014 edition Brian Jenkins, MD Although you have the flexibility to view the videos in any order, we strongly recommend that you watch the videos in the order in which

More information

THE RELATIONSHIP BETWEEN ACTIVITIES OF DAILY LIVING AND MULTIMORBIDITY. A VIEW FROM TELECARE

THE RELATIONSHIP BETWEEN ACTIVITIES OF DAILY LIVING AND MULTIMORBIDITY. A VIEW FROM TELECARE THE RELATIONSHIP BETWEEN ACTIVITIES OF DAILY LIVING AND MULTIMORBIDITY. A VIEW FROM TELECARE Edurne Alonso Morán Biostatician Researcher Collaborative Research of Osatek, SA, Public Society of the Basque

More information

Driving and Dementia. By Alison Morris OT.

Driving and Dementia. By Alison Morris OT. Driving and Dementia. By Alison Morris OT. Introduction. Early memory assessment has meant that more people are being diagnosed sooner with MCI or early dementia. This means that professionals are having

More information