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1 (2 ) Non HDL * Downloaded from ijdld.tums.ac.ir at 8:05 IRDT on Friday March 22nd 209 Non HDL : LDL :.. odds ratio Chi-Square %3/9 Non HDL-C %2 LDL-C. %3 : Non-HDL-C LDL-C. (CI %95 :4/-6/2 P=0/00) Non HDL-C odds ratio.(r:0/839 P=0/000). 2/6 (CI %95 :2/-3/2 P=0/0) LDL-C 5/. Non HDL-c : LDL-c Non HDL-c. LDL Non HDL-c Non HDL-c LDL-c : - ( )... : m39sadegh@yahoo.com : : :

2 209 Non HDL : Downloaded from ijdld.tums.ac.ir at 8:05 IRDT on Friday March 22nd 209 %25.[].[2] /7.[3 4] HDL-c 7-2.[5] Non HDL-c. [6 7] Non HDL-c [7]. Non -C LDL -C. HDL /. 0/ GOD-PAP 2..[] LDL-C ) Non HDL.[2] (HDL Non HDL Non.[3] HDL Non HDL-c.[4].[5] Non HDL-c -.[6] mg/dl Non HDL-c.[7] Non HDL-c. Non HDL-c LDL.[8] ( ) Non HDL LDL.[9] HDL.[0]

3 ( 2 ) Downloaded from ijdld.tums.ac.ir at 8:05 IRDT on Friday March 22nd 209. Non HDL %20 %5/3.(P=0/00) Non-HDL-C LDL-C.(r:0/83 P=0/000) Non HDL-C (r=0/45 P=0/00) (r=0/35 P=0/00) (r=0/22 P=0/00) P=0/00) (r=0/25 P=0/00). (r=0/33 P=0/00) (r=0/2. Non HDL (%95 CI. 90 :4/-6/2 P=0/00) 5/ mg/dl Non HDL LDL (%95 CI :2/-3/2 P=0/0) 2/6. 60 mg/dl LDL Non BMI HDL-C LDL-C.( 2 ) BMI.(3 ) HDL GOD-PAP (PTA). 0/5. Selectra II, Vital-Lab Co. LDL LDL-C Netherland. mg/dl 60 LDL-C. mg/dl 90 Non HDL-c /5 SPSS Chi-Square. Non HDL-C. 0/ %5 24) %3 9/3.( %37 2/2 LDL-C Non HDL-C.(P< 0/000) 3/9 8/4.(P< 0/000) - (n:578) (n:699) P P (9 ) (387) ( 07) (628) < 0/000 23/±3/ 8 26/9± 4/ 5 < 0/ /5±4/ 3 29 /± 4/ 3 (kg/m 2 ) BMI < 0/000 83/±0/ 7 95/4± / 8 < 0/ /6±0/ 4 94/5± 9/ 7 (Cm) < 0/000 8/±5/ 3 38/7± 2/ 3 < 0/ 000 0/6±5/ 34/5± 23/ 6 (mmhg) < 0/000 76/5±0/ 4 85/9± / 9 < 0/ /9±9/ 5 84/6± 3/ 3 (mmhg < 0/000 05/9±35/ 2 22/5± 37/ 4 < 0/ 000 0/8±36/ 2 34 /± 4/ 6 (mg/dl) LDL-C < 0/000 70/3±39/ 3 200/6± 40/ 2 < 0/ /7±38/ 2 2/0± 46/ 9 (mg/dl) < 0/000 39/5±6/ 3 34/9± 4/ 7 < 0/ 000 4/2±6/ 7 38 /± 6/ 3 (mg/dl) HDL-C < 0/000 34/9±92/ 3 248/8± 4/ 0 < 0/ /4±59/ 6 27/9± 29/ (mg/dl) < 0/000 30/8±40/ 5 65/6± 4/ 5 < 0/ 000 3/5±39/ 7 72 /8± 48/ 7 (mg/dl) Non HDL-C

4 2 Non HDL : HDL -2 P (Odds ratio) < 0/000 / 8 < 0/000 / 04 < 0/000 / 26 BMI < 0/000 / 49 2 Non HDL-C Downloaded from ijdld.tums.ac.ir at 8:05 IRDT on Friday March 22nd 209 LDL -3 P (Odds ratio) < 0/009 / 39 < 0/000 / 04 < 0/000 / 26 BMI < 0/000 / 49 Non HDL-c. LDL Non HDL-c LDL %3 %38/2 LDL. Non HDL-c 5/ Non HDL (%95 CI :4/-6/2 P=0/00). 90 mg/dl Non HDL 2/6 LDL LDL (%95 CI :2/-3/2 P=0/0). 60 mg/dl Non HDL-C BMI.(2 ) BMI LDL-C.(3 ) Non HDL-c (%8/4 %36). Non HDL-c.[8-20] Non HDL-c LDL-C ATP %3 %2/2. Non HDL LDL-C. %3/9 %22.[].. [ 3 4] [] HDL [2] [3-5]. 2. LDL Non HDL-c %3/ Non HDL-c.

5 ( 2 ) Downloaded from ijdld.tums.ac.ir at 8:05 IRDT on Friday March 22nd 209 Non HDL-c... Cook S, Weitzman M, Auinger P, Nguyen M, William H. Prevalence of a Metabolic Syndrome Phenotype in Adolescents, Findings From the Third National Health and Nutrition Examination Survey, Arch Pediatr Adolesc Med 2003; 57: Sirtori C, Chapman MJ, Assmann G, Fruchart JC, Shepherd J, European Consensus Panel on HDL-C. Raising high-density lipoprotein cholesterol with reduction of cardiovascular risk: the role of nicotinic acid-a position paper developed by the European Consensus Panel on HDL-C. Curr Med Res Opin 2004; 20: Packard CJ, Saito Y. Non HDL Cholesterol as a Measure of Atherosclerotic Risk. Journal of Atherosclerosis and Thrombosis 2004; : Lee KH, Son JC, Kim BT, Choi BH, Hye JS, Cha CK, et al. Non-HDL Cholesterol as a Risk Factor of Metabolic Syndrome in Korean Women. Korean J Obes 2007;6: Daghri NM, Al-Attas OS, Al-Rubeaan K.The atherogenic and metabolicimpact of non-hdl cholesterol versus other lipid sub-components among non-diabetic and diabetic Saudis. Lipids Health Dis 2007; 6: 9. Published online 2007 April 4. doi: 0.86/476-5X Cui Y, Blumenthal RS, Flaws JA, Whiteman MK, Langenberg P, Bachorik PS, Bush TL. Non High-Density Lipoprotein Cholesterol Level as a Predictor of Cardiovascular Disease Mortality. Arch Intern Med 200; 6: Bittner V, Hardison R, Kelsey SF, Weiner BH, Jacobs AK, Sopko G. Bypass Angioplasty Revascularization Investigation. Nonhighdensity lipoprotein cholesterol levels predict five-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI). Circulation 2002; 06: Srinivasan SR, Frontini MG, Xu J, Berenson G S. Utility of Childhood Non High-Density Lipoprotein Cholesterol Levels in Predicting [2 22] apob [6 7] LDL. [0].[5] [6] Non HDL LDL. Adult Dyslipidemia and Other Cardiovascular Risks: The Bogalusa Heart Study. Pediatrics 2006; 8: Srinivasan SR, Xu J, Rong T, Berenson GS. Usefulness of childhood non-high density lipoprotein cholesterol levels versus other lipoprotein measures in predicting adult subclinical atherosclerosis: The Bogalusa Heart Study. Pediatrics 2008; 2: :(4) 4. Azizi F, Rahmani M, Madjid M, Allahverdian S, Ghanbili J, Ghanbarian A, et al. Serum lipid levels in an Iranian population of children and adolescents: Tehran lipid and glucose study. Eur J Epidemiol 200; 7: : :(2) 3. Sharifi F, Mousavinasab SN, Soruri R, Saeini M, Dinmohammadi M. High Prevalence of Low High-Density Lipoprotein Cholesterol Concentrations and Other Dyslipidemic Phenotypes in an Iranian Population. Metabolic Syndrome and Related Disorders 2008; 6: Sharifi F, Mousavinasab SN, Saeini M, Dinmohammadi M. Prevalence of metabolic syndrome in an adult urban population of the west of Iran. Exp Diabetes Res 2009;

6 23 Non HDL : Downloaded from ijdld.tums.ac.ir at 8:05 IRDT on Friday March 22nd ATPIII IDF :(4) 7 6. Gardner CD, Winkleby MA, Fortmann SP. Population frequency distribution of non-high density lipoprotein cholesterol (Third National Health and Nutrition Examination Survey [NHANES III], ). Am J Cardiol 2000; 86: Jiang R, Schulze MB, Li T, Rifai N, Stampfer MJ, Rimm EB, et al. Non-HDL cholesterol and apolipoprotein B predict cardiovascular disease events among men with type 2 diabetes. Diabetes Care 2004; 27: Miller M, Ginsberg HN, Schaefer EJ. Relative Atherogenicity and Predictive Value of Non- High-Density Lipoprotein Cholesterol for Coronary Heart Disease. The American Journal of Cardiology 2008; 0: Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002; 06: Bittner V. Non-high-density lipoprotein cholesterol and cardiovascular disease. Curr Opin Lipidol 2003; 4: Walldius G, Jungner I, Holme I, Aastveit AH, Kolar W, Steiner E. High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. Lancet 200; 358: Vega GL, Grundy SM. Does measurement of apolipoprotein B have a place in cholesterol management? [editorial]. Arteriosclerosis 990; 0:

Disclosures. Pediatric Dyslipidemia Casey Elkins, DNP, NP C, CLS, FNLA. Learning Objectives. Atherogenesis. Acceptable Values

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