F E R M E N T O I L C O M P E L E X. What happened in Fermentoil? Why is the texture of Fermentoil felt lighter than regular oil?

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1 F E R M E N T O I L C O M P E L E X KR Patent / PCT Pending New generation of plant oil for developing your cosmetics Why is the texture of Fermentoil felt lighter than regular oil? What happened in Fermentoil?

2 Oil & Cosmetics Fermentoil Organic Silicon 1 2 Choosing the best oil can make a difference in your formulation Creating new category of oil through unique fermentation technology Mineral Synthetic Plant

3 Oil Fermentation Technology Pseudozyma sp. SY-16[KCTC 8950P] Odorless in aerobics condition It changes the substance in plant oil by producing enzymes It produces various types of polysaccharides and lipids KRIBB have researched to develop organisms that can clean the waste oil in the ocean They applied in coastal area(tae-an, Korea) to decompose the oil leakage in 2007 The patent was registered through cooperation with Korea Research Institute of Bioscience & Biotechnology

4 Development Background

5 Fermentation Process of Fermentoil Glycerol Triglyceride H O H C H C O O Fatty Acid H H H H C C C OH OH OH H C O O H H O Attack point O O - Free Fatty Acid O - Catabolism O O - MEL (Mannosylerythritol lipid) Pseudozyma sp. SY- 16[KCTC 8950P] O

6 Changes through Fermentation Composition of Plant oil VS Composition of Fermentoil Triglyceride Free fatty acid < 1% α-tocopherol Inactive Polyphenols Triglyceride Free fatty acid 4~6% MEL >0.5% > α-tocopherol > Active Polyphenols Fermentoil have 6 effects of non-greasy feeling, moisturizing, higher penetration, emulsifying capacity, free fatty acid, and anti-oxidation.

7 Surface tension (dyne/cm) Surface tension MELavo Triglyceride Free fatty acid Hydrophobic interaction Fermentoil Regular oil MEL concentration in olive oil(%,v/v) MEL & Free fatty acid in Fermentoil decrease surface tension of oil

8 Spreadability Moisturizing Effect H 2 O H 2 O Damaged skin barrier 1. High affinity to human skin 2. Excellent penetration 3. Repair the skin barrier 4. Formation of moisturizing film

9 Increase in standardized moisture contents (A.U.) Spreadability Moisturizing Effect 0.88 Applied Not applied Fermentoil Olive 0.7 Olive Not treated In vivo study, 10 persons Trans-epidermal water loss (TEWL) Cream containing 3% Fermentoil Olive Cream containing 3% Olive oil Fermentoil shows long lasting moisturizing effect compare with olive oil

10 Penetration Penetration capability has been enhanced.

11 Improved Emulsifying Capacity Olive oil ph9.0 ph7.0 ph5.0 Fermentoil Olive ph9.0 ph7.0 ph5.0 The emulsifying capacity of Fermentoil Olive can be showed in a wide range of ph comparing to other olive oil

12 Analysis of Free fatty acid Value Detection method HPLC Analysis Oleic acid Linoleic acid Linoleic acid Oleic acid

13 Production Process of Fermentoil Magnification : X1000

14 Fermentation from LABIO Comparison between decomposition & Fermentation 9 Acid Value(mg KOH/g oil) 250 Peroxidation Value (meq/kg) General (Rancid) Fermentoil General (Fresh) 0 General (Rancid) Fermentoil General (Fresh) General (Rancid) Fermentoil General (Fresh) Acid Value (mg KOH/g oil) Peroxidation Value (meq/kg) Fermentation process raises the Acid value while maintaining Peroxidation Value.

15 Summary of Improvement Non-greasy Feeling Anti-oxidative effect Skin Absorption Fermentoil Regular plant oil Moisturizing Odorless & Colorless Emulsifying Capacity General plant oil has been improved in quality and compatibility through LABIO s fermentation technology

16 Best solution for Fermentoil Advantage 1 Cost-effectiveness Fermentoil Olive Advantage 2 Additional effect Each Fermentoil has different effects, when it comes together the additional effect can be expected. Fermentoil Shiunko Fermentoil Argan Advantage 3 Better texture BIO-Technology brings the oil with the fresher feeling, also with the better efficacy. That comes through the process we call Fermentation. It is the most natural but delicately controlled process. Fermentoil Sunflower seed Fermentoil Glycyrrhiza

17 History & Benefits Olive oil Material Oleic acid Vitamin E Polyphenol Benefits Moisturizing Anti-aging Antioxidant activity Protection against UVB damage Antio-inflammation Story Olive oil is used in traditional medicine and food from 6,000 years ago Olive oil used for Fermentoil Olive is grown with fertile soil and rich sunlight of Italy

18 History & Benefits Glycyrrhiza uralensis oil Recommended for sensitive skin Material Glycyrrhizin :Liquirtin Benefits Anti-oxidation Anti-inflammation Anti-irritation Brightening Story Glycyrrhiza uralensis has been used with most medicinal herbs together for its multi-functional effect in Korean traditional prescription. Glycyrrhiza uralensis has been known to help promotion of blood circulation, detoxification according to Dongeuibogam.

19 History & Benefits Argan oil Recommended for sensitive skin Material Linolenic acid Oleic acid Vitamin E Polyphenol Benefits Moisturizing Anti-sebum Anti-aging Wound healing Anti-acne Story Called as a Golden liquid presented from God Popular oil for hair care with its nutrition Rigidly selected Argan grown under optimal conditions of Morocco Valuble oil that only 1 liter is obtained from 7 trees

20 History & Benefits Shiunko oil Recommended for sensitive skin Material Z-ligustilide Shikonin Benefits Anti-oxidation Anti-microbes Proliferation Collagen secretion Anti-inflammation Story Shiunko is traditional pointment which is made of Angelica sinensis and Lithospermum erythorhizon. The dying of Lithospermum erythorihizon has been loved as a symbol of emperor and elegance from 2000 years ago.

21 History & Benefits Sunflower seed oil Material Linoleic acid Phytosterol Vitamin E Polyphenol Benefits Moisturizing Anti oxidant activity Improvement of skin irritation Bactericide Story Sunflower seed has been used by American Indian tribes for body painting, decorations, ointments, skin and hair care. Sunflower is a plant which has strong self purification capacity, Sunflower was used for purifying contaminated waste water site in Ohio and removed more than 95% of uranium in 24h(Dushenkov et al., 1997 a,b, 1995)

22 Summary Fermentoil Complex INCI name Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, Olea Europaea (Olive) Fruit Oil, Helianthus Annuus(Sunflower) Seed Oil, Argania Spinosa Kernel Oil, Angelica Gigas Root Extract, Lithospermum Erythororhizon Root Extract, Glycyrrhiza Uralensis (Licorice) Root Extract, Define Fermentoil Complex is mixture version of Fermentoil series(fermentoil Olive, Fermentoil Argan, Fermentoil Sunflower seed) and two different Fermentoil from Korean herb-glycyrrhiza uralensis, Shiunko) In comparison with Regular Oil, It has better texture with high moisturizing and penetration effect. Thanks to our technology Fermentation, The advantages are followed naturally without any chemical additives like silicone. Physical characteristic Viscous Liquid(Light yellow to yellow) Function Moisturizing Anti-oxidant activity Anti-sebum Anti-inflammation Anti-irritation Recommended Dosage Up to 99% Depending on formulation

23 T H A N K Y O U New generation of plant oil for developing your cosmetics

KR Patent / PCT Pending

KR Patent / PCT Pending The Quality of Plant Oil Fermentoil KR Patent / PCT Pending New generation of plant oil for developing your cosmetics Olive / Argan / Green tea seed / Meadowfoam seed oil / Jojoba seed oil / Sunflower

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