COSMOSIL HPLC Columns

Transcription

1 COSMOSIL HPLC Columns Sample Organic Compounds (low M.W.) Reversed 3C 18 -EB L1 Octadecyl Excellent for basic compounds 3 µm silica packing material C 18 -MS-II L1 Octadecyl Multi-purpose C 18 Monofunctional silylation on ultra-pure silica gel for separation of the widest range of compounds C 18 -AR-II L1 Features strong acid resistance and suitable for acidic compounds and peptides C 18 -PAQ L1 Reversed phase, compatible with 100% water based mobile phase. Suitable for hydrophilic compounds Cholester L101 Cholesteryl PBr - Pentabromobenzyl group πnap - Naphtylethyl PYE - Pyrenylethyl NPE - Nitrophenylethyl PBB-R - Pentabromobenzyl PFP L43 Pentafluorophenyl CN-MS L10 Cyanopropyl C 22 -AR-II - Docosyl Usable under the same condition as C 18 Unique rigid cholesteryl structure improves separation Separate hydrohilic compounds in reversedphase conditions Stronger π-π interaction than Phenyl Most powerful π-π interaction utilizing π-π interaction and dipoledipole interaction utilizing dispersion force by dipoledipole interactions. Great reproducibility using isocratic elution mode Australia & New Zealand contact: info@winlab.com.au or call

2 Sample Normal Reversed Gel Permeation Monosaccharides Oligosaccharides Ionexchange C 8 -MS L7 Octyl Alkyl chain s except C 18 C 4 -MS L26 Butyl TMS-MS L13 Trimethyl PE-MS L11 Phenylethyl π-π interaction SL-II L3 - Suitable for preparative separation HILIC L104 Triazole Retains highly polar compounds that would not be retained in C 18 Sugar-D - Secondary/ Tertiary Amine NH 2 -MS L8 Aminopropyl Suitable for monosaccharides, oligosaccharides Primary amine bonded Protein-R L1 Octadecyl Provides improved separation, high recovery rate, and acid resistance C 18 -AR-300 L1 Octadecyl Wide pore type reversed phase s C 8 -AR-300 L7 Octyl C 4 -AR-300 L26 Butyl Ph-AR-300 L11 Phenyl Diol-120-II L20 Diol Silica-based gel filtration Sample MW (Protein) 5, ,000 Da Diol-300-II Silica-based gel filtration Sample MW (Protein) 10, ,000 Da Diol-1000-II Silica-based gel filtration Sample MW (Water Soluble Polymer) 50, ,000 Da Type Q Quaternary Ammonium Type Anion-exchange Type - For Purification Target Sample: Acidic / DNA Type Q-N Anion-exchange Type For Ultra-fast Analysis, Precise Analysis Australia & New Zealand contact: info@winlab.com.au or call

3 Sample Hydrophobic Target Sample: Acidic / DNA Type S Sulfopropyl Type Cation-exchange Type For Purification Target Sample: Basic Type S-N Type M Type M-N Quaternary Ammonium Type/ Sulfopropyl Type Cation-exchange Type - For Ultra-fast Analysis, Precise Analysis - Target Sample: Basic Amphoteric ion-exchange Type - For Purification - Target Sample: All Amphoteric ion-exchange Type - For Precise Analysis - Target Sample: All HIC - - Suitable for separation of peptide, and there is only a little less in enzyme activity and the teriary structure of proteins Fullerenes - Buckyprep - Pyrenylpropyl Carbon Nanotubes Gel Permeation Buckyprep- D Buckyprep- M - Nitro-carbazoyl - Phenothiazinyl PBB - Pentabromobenzyl PYE - Pyrenylethyl NPE - Nitrophenylethyl CNT Standard for fullerene separation Designed for separation of fullerene derivatives Designed to separate metallofullerenes Designed for preparative separation of C 60, C 70 of Fullerenes and structural isomers of derivatived fullerene of carbon nanotubes Australia & New Zealand contact: info@winlab.com.au or call

4 Selection Guide Organic Compounds (Low M.W.) Octadecyl group bonded (C 18 ODS) are recommended as first-choice s for separations of organic compounds (Low M.W.). If there is not enough separation or no retention using COSMOSIL C 18 s, COSMOSIL series offer many kinds of special s. Please click here for the selection guide for C 18 s Saccharides COSMOSIL Sugar-D is recommended for the separation of monosaccharides and oligosaccharides as a first-choice. For the separation of sugar derivatives, COSMOSIL C 18 -PAQ is suitable as well. Please select based on the separation mode. Fullerenes COSMOSIL Buckyprep is most suitable for the separation of fullerenes. COSMOSIL Specialty Columns Click here Australia & New Zealand contact: info@winlab.com.au or call

5 Specifications The (U.S. Pharmacopeia) specifications are listed below with the recommended COSMOSIL HPLC s. Description Recommended Columns L1 Octadecyl silane chemically bonded to porous silica or ceramic micro-particles, 1.7 to 10 m in diameter, or a monolithic rod COSMOSIL 3C 18 EB COSMOSIL C 18 -MS-II COSMOSIL C 18 -AR-II COSMOSIL C 18 -PAQ COSMOSIL C 18 -AR-300 COSMOSIL Protein-R L3 Porous silica particles, 5 to 10 µm in diameter COSMOSIL SL-II L7 L8 L10 L11 L13 L20 L26 L43 L101 L104 Octylsilane chemically bonded to totally porous silica particles, 1.7 to 10 µm in diameter An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 1.5 to 10 µm in diameter, or a monolithic silica rod. Nitrile groups chemically bonded to porous silica particles, 3 to 10 µm in diameter Phenyl groups chemically bonded to porous silica particles, 1.7 to 10 µm in diameter Trimethylsilane chemically bonded to porous silica particles, 3 to 10 µm in diamete Dihydroxypropane groups chemically bonded to porous silica particles, 5 to 10 µm in diameter Butyl silane chemically bonded to totally porous silica particles, 3 to 10 µm in diameter Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer, 1.5 to 10 µm in diameter Cholesteryl groups chemically bonded to porous or non-porous silica or ceramic micro-particles, 1.5 to 10 µm in diameter, or a monolithic rod. Triazole groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter COSMOSIL C 8 -MS COSMOSIL C 8 -AR-300 COSMOSIL NH 2 -MS COSMOSIL CN-MS COSMOSIL PE-MS COSMOSIL Ph-AR-300 COSMOSIL TMS-MS COSMOSIL Diol-120-II COSMOSIL Diol-300-II COSMOSIL Diol-1000-II COSMOSIL C 4 -MS COSMOSIL C 4 -AR-300 COSMOSIL PFP COSMOSIL Cholester COSMOCORE Cholester COSMOSIL HILIC Distributor in Australia and New Zealand: WINLAB PTY LTD 2 Pinacle St, Brendale, Queensland, Australia, 4500 PO Box 5007, Brendale, Queensland, Australia, 4500 Ph: : Fax: info@winlab.com.au Australia & New Zealand contact: info@winlab.com.au or call