Bioenergetics: Energy for Exercise. Chapter 3 pp 28-47
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1 Bioenergetics: Energy for Exercise Chapter 3 pp 28-47
2 ATP ATP Adenosine Ribose 3 Phosphates
3 ATP
4 ATP
5 ATP
6 ATP ATP
7 ATP ATP
8 ATP ATP Energy Out ADP + P
9 ATP ATP Energy Out ADP + P
10 ATP ATP Energy Out Energy In ADP + P
11 ATP
12 ATP Energy
13 Fuels for Exercise
14 Fuels for Exercise CARBOHYDRATES
15 Fuels for Exercise CARBOHYDRATES Fats
16 Fuels for Exercise CARBOHYDRATES Fats Proteins
17 Fuels for Exercise CARBOHYDRATES Fats Proteins Phoshocreatine
18 Bioenergetics ATP is the only source of energy recognized by the cells Only a small amount of ATP is stored inside the muscle cells
19 Bioenergetics Energy Out (muscle contraction) Energy In (food sources)
20 ATP ATP Energy Systems or SARCOPLASM Krebs Cycle Lactic Acid βeta Oxidation PC ATP
21 ATP Anaerobic Aerobic or SARCOPLASM Krebs Cycle Lactic Acid βeta Oxidation PC ATP Fatty acids
22 Bioenergetics
23 Bioenergetics Making or Recycling ATP
24 Bioenergetics Making or Recycling ATP Fuels/Systems
25 Bioenergetics Making or Recycling ATP Fuels/Systems 1. Phosphocreatine /ATP-PC (phosphagen system)
26 Bioenergetics Making or Recycling ATP Fuels/Systems 1. Phosphocreatine /ATP-PC (phosphagen system) 2. Carbohydrates/Glycolysis (lactic acid system)
27 Bioenergetics Making or Recycling ATP Fuels/Systems 1. Phosphocreatine /ATP-PC (phosphagen system) 2. Carbohydrates/Glycolysis (lactic acid system) 3. Carbohydrates, Fats and Proteins / Aerobic (oxidation)
28 ATP-PC System (enzyme) How does it work?
29 ATP-PC System (enzyme) How does it work?
30 ATP-PC System (enzyme) How does it work?
31 ATP-PC System (enzyme) How does it work?
32 ATP-PC System
33 ATP-PC System
34 ATP-PC System
35 ATP-PC System
36 ATP-PC System
37 ATP-PC System Advantages?
38 ATP-PC System Advantages? Disadvantages?
39 Creatine Supplement
40 Creatine Supplement Does it work?
41 Creatine Supplement Does it work? THE WINNING EDGE 3.1 p.32
42 Creatine Supplement Does it work? THE WINNING EDGE 3.1 p.32 Can increase creatine levels inside muscle
43 Creatine Supplement Does it work? THE WINNING EDGE 3.1 p.32 Can increase creatine levels inside muscle Improve short, high intensity performance
44 Creatine Supplement Does it work? THE WINNING EDGE 3.1 p.32 Can increase creatine levels inside muscle Improve short, high intensity performance Small increase in muscle strength
45 Glycolysis
46 GLYCOLYSIS
47 GLYCOLYSIS Where?
48 GLYCOLYSIS Where? What fuel?
49 GLYCOLYSIS Where? What fuel? How? reactions, Enzymes
50 GLYCOLYSIS Where? What fuel? How? reactions, Enzymes What is produced? 1. ATP 2. Hydrogens (NADH) 3. Pyruvate or Lactate
51 Glycolysis Glucose Carbohydrates Glucose Glycogen Glucose = C6 H12 O6
52 Glycogen
53 Glycogen
54 Glycogen
55 Glycogen
56 ATP required Glycolysis
57 Glycolysis Acetyl-CoA Acetyl-CoA End product = pyruvate
58 ATP Produced Glycolysis Acetyl-CoA Acetyl-CoA End product = pyruvate
59 ATP Produced Glycolysis Acetyl-CoA Acetyl-CoA End product = pyruvate
60 ATP Produced Glycolysis Acetyl-CoA Acetyl-CoA End product = pyruvate
61
62
63
64
65 Glycolysis Acetyl-CoA Aerobic system (Electron Transport Chain)
66 Glycolysis ATP Acetyl-CoA Aerobic system (Electron Transport Chain)
67 Glycolysis ATP Pyruvate (pyruvic acid) 1. Actyl-CoA 2. Lactate (lacatic acid) Acetyl-CoA Aerobic system (Electron Transport Chain)
68 Glycolysis ATP Pyruvate (pyruvic acid) 1. Actyl-CoA 2. Lactate (lacatic acid) H (NADH) 1. Aerobic system 2. Convert pyruvate to lactate Acetyl-CoA Aerobic system (Electron Transport Chain) 1.
69 Glycolysis
70 Glycolysis Advantages?
71 Glycolysis Advantages? Disadvantages?
72 ATP Anaerobic Aerobic or SARCOPLASM Krebs Cycle Lactic Acid βeta Oxidation PC ATP Fatty acids
73 Intensity Anaerobic Systems Note the over lapping of the systems
74 Aerobic Metabolism
75 Aerobic Metabolism or Oxidative Phosphorylation
76 Aerobic Metabolism or Oxidative Phosphorylation Where? Mitochondria
77 Aerobic Metabolism or Oxidative Phosphorylation Where? Mitochondria Three pathways
78 Aerobic Metabolism or Oxidative Phosphorylation Where? Mitochondria Three pathways Krebs cycle
79 Aerobic Metabolism or Oxidative Phosphorylation Where? Mitochondria Three pathways Krebs cycle Beta oxidation (fats only)
80 Aerobic Metabolism or Oxidative Phosphorylation Where? Mitochondria Three pathways Krebs cycle Beta oxidation (fats only) Electron transport chain
81 Acetyl-CoA Glucose, Fat and Protein Krebs cycle
82 Beta Oxidation Fat
83 Beta Oxidation Fat
84 Acetyl-CoA Sarcoplasm Mitochondria Beta Oxid
85 Acetyl-CoA Amino acids from protein converted into Acetyl Co-A
86 Krebs Cycle
87 Krebs Cycle
88 Electron Transport Chain
89 Electron Transport Chain Where? Mitochondria
90 Electron Transport Chain Where? Mitochondria What is produced?
91 Electron Transport Chain Where? Mitochondria What is produced? ATP
92 Electron Transport Chain Where? Mitochondria What is produced? ATP H2O
93 Electron Transport Chain Where? Mitochondria What is produced? ATP H2O How?
94 Electron Transport Chain Where? Mitochondria What is produced? ATP H2O How? Electrons from Hydrogens
95 Electron Transport Chain From Glycolysis or from the Krebs Cycle Electrons
96 Electron Transport Chain
97 Electron Transport Chain What roles does oxygen play?
98 Electron Transport Chain What roles does oxygen play?
99 Electron Transport Chain
100 Electron Transport Chain What happens when not enough oxygen is supplied to the muscles?
101 Electron Transport Chain What happens when not enough oxygen is supplied to the muscles? Hydrogens from glycolysis?
102 Electron Transport Chain What happens when not enough oxygen is supplied to the muscles? Hydrogens from glycolysis? Pyruvate to Lactate
103 Oxygen ATP H2O
104 Oxygen Lactic Acid ATP H2O
105 Summary
106 Summary
107 ATP ATP Summary or SARCOPLASM Krebs Cycle Lactic Acid βeta Oxidation PC ATP Fatty Acid
108 Fatty Acids Summary Beta Oxid
109 Proteins Only 5-10% of energy during exercise
110 ATP Tally Phophocreatine: 1 ATP Carbohydrates/Glucose (C6 H12 O6) Glycolysis: 2 ATP Aerobic: 34 ATP Fatty Acid (C16 H32 O2) ATP
111 Efficiency What percentage of the energy from ATP goes into doing work? Where does the rest of the energy go?
112 Aerobic/Anaerobic Interaction The energy systems: time at maximal capacity
113 Aerobic/Anaerobic Interaction Seconds Minutes Aerobic Anaero bic
114 Summary
115 Summary
116 Summary
117 Summary
118 ATP Summary or SARCOPLASM Krebs Cycle Lactic Acid βeta Oxidation PC ATP Fatty acids
119 Summary of Energy Systems
120 Summary of Energy Systems SYSTEM ATP-PC Glycolysis Aerobic
121 Summary of Energy Systems SYSTEM Fuel ATP-PC Glycolysis Aerobic PC Carbohydrat e (glycogen & glucose) Carbohydrat e (glycogen & glucose) Fat Protein
122 Summary of Energy Systems SYSTEM Fuel Waste Product ATP-PC PC P and Cr Glycolysis Aerobic Carbohydrat e (glycogen & glucose) Carbohydrat e (glycogen & glucose) Fat Lactic Acid CO2 and H20 Protein
123 Summary of Energy Systems SYSTEM Fuel Waste Product ATP ATP-PC PC P and Cr 1 Glycolysis Carbohydrat e (glycogen & glucose) Lactic Acid 2 Aerobic Carbohydrat e (glycogen & glucose) Fat CO2 and H Protein?
124 Summary of Energy Systems SYSTEM Fuel Waste Product ATP Speed ATP-PC PC P and Cr 1 Fastest Glycolysis Carbohydrat e (glycogen & glucose) Lactic Acid 2 Fast Aerobic Carbohydrat e (glycogen & glucose) Fat CO2 and H20 34 Slow 129+ Slower Protein??
125 Summary of Energy Systems SYSTEM Fuel Waste Product ATP Speed Endurance ATP-PC PC P and Cr 1 Fastest Second Glycolysis Carbohydrat e (glycogen & glucose) Lactic Acid 2 Fast Minutes Aerobic Carbohydrat e (glycogen & glucose) Fat CO2 and H20 34 Slow Hours 129+ Slower Unlimited Protein???
126 Summary of Energy Systems SYSTEM Fuel Waste Product ATP Speed Endurance ATP-PC PC P and Cr 1 Fastest Second Power/ Strength Glycolysis Carbohydrat e (glycogen & glucose) Lactic Acid 2 Fast Minutes Speed Aerobic Carbohydrat e (glycogen & glucose) Fat CO2 and H20 34 Slow Hours 129+ Slower Unlimited Endurance Protein???
127 Summary of Fuels Fuels provide the energy for the systems to make ATP
128 Summary of Fuels FUEL STORED ENERGY SYSTEM Fuels provide the energy for the systems to make ATP
129 Summary of Fuels FUEL STORED Phosphocreatine Phosphocreatine ENERGY SYSTEM ATP-PC Fuels provide the energy for the systems to make ATP
130 Summary of Fuels FUEL STORED Carbohydrates Phosphocreatine Phosphocreatine Glycogen Glucose ENERGY SYSTEM ATP-PC Glycolysis Aerobic Fuels provide the energy for the systems to make ATP
131 Summary of Fuels FUEL Phosphocreatine Carbohydrates Fats STORED Phosphocreatine Glycogen Fatty acids Glucose ENERGY SYSTEM ATP-PC Glycolysis Aerobic Aerobic Fuels provide the energy for the systems to make ATP
132 Summary of Fuels FUEL Phosphocreatine Carbohydrates Fats Protein STORED Phosphocreatine Glycogen Fatty acids Glucose Amino acids ENERGY SYSTEM ATP-PC Glycolysis Aerobic Aerobic Aerobic Fuels provide the energy for the systems to make ATP
133 Summary: Fuels and Energy ATP-PC System Glycogen PC + ADP 1 C + ATP Glucose Glycerol Glucose 6-phosphate 2 Phosphoglyceraldehyde Glycolysis Triglycerides Lactic Acid Pyruvic Acid Fatty acids β-ox Acetyl CoA Amino Acids Proteins Table 3.2 Ketone bodies C 4 C 6 Kerb s Cycle 3 NADH ETS C 5 FADH Urea 4 Aerobic Systems
134 Control of Bioenergetics What is a rate limiting enzyme?
135 Control of Bioenergetics Pathway Rate-limiting Enzyme Stimulators Inhibitors ATP-PC Creatine kinase ADP ATP Glycolysis Phosphofructokinase ADP, ph ATP, ph Krebs Isocitrate Dehydrogenasese ADP, Ca, NAD ATP, NADH E.T.C. Cytochrome oxidase ADP, P ATP
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