PRELIMINARY SCIENTIFIC PROGRAM :50 Meet the experts- Molecular mechanisms in IBD from basic science to therapy. Franco-Romanian Meeting

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1 PRELIMINARY SCIENTIFIC PROGRAM RCCC Annual Meeting 27th-29th of SEPEMBER 2018 Thursday 27 th of September Registration :50 Meet the experts- Molecular mechanisms in IBD from basic science to therapy Franco-Romanian Meeting Session I Introduction Matthieu Allez, Mircea Diculescu Short conferences Epidemiology of IBD across Europe Mircea Diculescu (Bucarest, Roumanie ) IBD and Nutrition Does it matter? Xavier Hebuterne (Nice, France) Coffee Breack Session II Clinical case I- Crohn s Disease Peri-ileal Abscesss - Matthieu Allez (Fr), Roxana Zaharie (RO)

2 Presentation of the case with multiple steps (drainage, nutrition, surgery versus medical therapy post op management) Short Conference IBD and Pregnancy Lucine Vuiton (Besancon, France) Round table Lunch Session III Clinical case II- Crohn s disease Fistulising perianal Crohn s Disease Franck Carbonnel ( France), Roxana Zaharie (RO) Presentation of the case with multiple steps (exploration, drainage medical therapy management) Round table Clinical case III Ulcerative colitis Mild left ulcerative colitis - Lucine Vuiton (France), Mihai Ciocirlan (RO) Presentation of the case with multiple steps (control with 5 ASA, poor adherence and then relapse with ASA failure - management) Round Table Coffee Breack Session IV

3 Clinical Case IV Ulcerative Colitis Severe acute colitis - Xavier Hebuterne (FR), Oana Stanciulea (RO) Presentation of the case with multiple steps (assessment of severity, management, medical therapy and discussion on surgery, management) Round Table 17, CONFERENCE New therapeutic objectives in the management of IBD Franck Carbonnel (France) Conclusions of the meeting. Matthieu Allez, Mircea Diculescu Pharma Symposium ALFASIGMA Pharma Symposium WELLCOME COCKTAIL Friday 28 th of September Registration Opening Ceremony. Cristina Cijevschi, Mircea Diculescu Session I. IBD in Romania Epidemiological update. Adrian Goldis, Razvan Iacob, Catalina Mihai Studiul EPIROM Studiul IBDPROSPECT New epidemiological data in Romania - IBD Prospect. Catalina Mihai, Cristina Cijevschi Prelipcean

4 Epidemiology of malnutrition in IBD patients- data from IBD Prospect. Maria Ciocîrlan, Razvan Iacob, Liana Gheorghe, Daniela Dobru, Alina Tantau, Adrian Goldis, Gabriel Constantinescu, Cristina Cijevschi, Anca Trifan, Mircea Diculescu Prezentare Bucuresti, IC Fundeni Prezentare Timisoara HU-RO Adrian Goldis Prezentare Iasi Prezentare Cluj Coffee Break Session II. Best practice in IBD care: role of IBD centers. Liana Gheorghe, Lucian Negreanu, Alina Tantau 1. The backbone of excellence strategy in IBD Liana Gheorghe 2. Minimal criteria for an IBD centre Lucian Negreanu 3. Best care of IBD: Cluj-Napoca experience Alina Tantau 4. Best care of IBD: Timisoara experience Adrian Goldis 5. Best care of IBD: Constanta Eugen Dumitru 6. IBD in primary care: educate GPs to recognize, refer and manage IBD patients - Ligia Mosneaga 7. Patients empowerment: key actions - Isabella Grosu State of the Art Lecture I. Malignancies and IBD- Andreas Sturm (Germany) Pharma Symposium:ABBVIE Lunch break

5 Educational Session. The evolution of the treatment landscape and personalized medicine approaches for management of UC Session III. Management of IBD from childhood to elderly Daniela Serban, Dan Gheonea, Mariana Jinga Peculiarities of therapeutic approach in children with IBD - Daniela Serban Transition in IBD - from child to adulthood - Daniel Vasile Balaban, Mariana Jinga Long term management of IBD during adulthood - Dan Ionut Gheonea Managing IBD in elderly - Cristina Cijevschi Prelipcean, Catalina Mihai Coffee break Session IV. Standard of care in endoscopy for IBD- Cristian Gheorghe, Eugen Dumitru, Adrian Saftoiu Upper G-I endoscopy, videocapsule, enteroscopy: how to choose, how to exam, and how to write a quality report - Lucian Negreanu Quality of the colonoscopy and its reporting is mandatory for standard of care in IBD - Cristian Gheorghe High resolution and chromoendoscopy- standard of care for diagnosis and therapy of IBD dysplasia - Eugen Dumitru (Endoscopic) ultrasound for diagnosis of perianal Crohn's disease - Adrian Saftoiu Session V. Current therapeutic strategies in Daniela Dobru, Gabriel Constantinescu, Mirela Ionescu

6 1. Evolution of treatment targets and strategies in IBD - Catalina Diaconu, Gabriel Constantinescu 2. Influence of microbiota in the strategy of treatment in IBD - Liana Gheorghe 3. Biologic therapy and new oral targeted therapies in IBD - Cristian Țieranu, Mirela Ionescu 4. Personalized therapy in IBD Lucian Negreanu Pharma Symposium TAKEDA Romanian IBD Society Dinner Saturday 29th of September Session VI. Original Research Forum. Chair: Ciprian Brisc, Bogdan Mateescu, Carmen Preda 1) Diet in ethiopathogenesis of inflammatory bowel diseases: an original prospective study. Carmen Preda, Doina Proca, Teodora Manuc, Mircea Manuc, Mircea Diculescu. 2) Correlations between US measurements and biomarkers in IBD. Anda Les, Razvan Iacob, Liana Gheorghe, Radu Dumitru, Cristian Gheorghe. 3) Histopathological features the last piece of the puzzle in differentiation of Crohnʼs disease from ulcerative pancolitis. Monica Cojocaru, Gabriel Becheanu, Mona Dumbrava, Liana Gheorghe, Bogdan Cotruta, Razvan Iacob, Roxana Vadan, Oana Stanciulea, Ioana Lupescu, Cristian Gheorghe. 4) Diagnostic yield of small-bowel capsule endoscopy in suspected Crohn's disease. Ana Maria Singeap, Oana Stoica, Carol Stanciu, Anca Trifan. 5) Lipidomic Signatures Of Inflammatory Bowel Diseases: In Search Of Putative Biomarkers By Ultra High Performance Liquid Chromatography/Mass Spectroscopy. Cristian Tefas, Carmen Socaciu, Corina Morar, Marcel Tanțău.

7 6) Quality of Life in IBD patients- what is good enough? State M., Voiosu T., Bengus A., Mateescu B. 7) Capsule endoscopy in a treat to target approach in Crohn s disease-a case series. Stemate Ana, Sadagurschi Roxana, Babiuc Ruxandra, Negreanu Lucian. 8) Predictive factors for nonresponse to imunosupresive and biologic therapy in Ibd patients in a referal center. Filip C., Goldis R., Goldis A. 9) Microbiota, IBD and joint impairment: a causal triad or a clinical epiphenomenon?. Anca Cardoneanu, Elena Rezus, Cristina Cijevschi, Aida Badescu, Igor Jelikovschi, Catalina Mihai State of the Art Lecture II. "Innovation in IBD - How do We Advance the Field?" Florin Selaru (USA) Pharma Symposium: MSD Coffee Break Session VII. Novel therapeutics in IBD. Chair: Anca Trifan, Corina Pop, Andrada Seicean Multidisciplinary approach of a patient with IBD Bioethical concerns and engagement in patient care with inflammatory bowel disease. Elena Toader, Mihaela Dranga Review of recent Clinical Trials in IBD. Liana Gheorghe, Roxana Vadan Conclusions. Prizes Award Ceremony RCCC General Assembly, changes in the Statute

8 Poster session Parallel Session Friday SALA TRANSILVANIA IBD Nurse Symposium Lunch break Leading Change in IBD Coffee Break Patients Forum ASPIR

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