The Clinical Effects of Carthami-Flos Pharmacopuncture on Posterior Neck pain of Menopausal Women

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1 ISSN Journal of Pharmacopuncture 71 Received : Nov 10, 2011 Revised : Nov 25, 2011 Accepted : Nov 30, 2011 KEY WORDS: Carthami-Flos; Neck pain, Pharmacopuncture; menopause; VAS; NDI; MENQOL. The Clinical Effects of Carthami-Flos Pharmacopuncture on Posterior Neck pain of Menopausal Women Jae-Yeon Park*, Kyung-Jin Yun*, You-Jin Choi**, Min-Seok Kim**, Sung-Jin Yu***, Cham-Kyul Lee*, Jeong-Du Roh** and Eun-Yong Lee* Department of Acupuncture & Moxibustion, Semyung University oriental medicine hospital, Chungju, Korea* Department of Acupuncture & Moxibustion, Semyung University oriental medicine hospital, Jecheon, Korea** Department of Oriental Gynecology, Semyung University oriental medicine hospital, Chungju, Korea*** Abstract Objectives: The purpose of this research was to examine the effect of Carthami-Flos Pharmacopuncture on posterior neck pain of menopausal women. Methods: We treated 20 female patients with neck pain patient(45-60 yr) into two groups and treated Group A with Carthami-Flos Pharmacopuncture and common acupuncture and Group B with common acupuncture. The efficacy of treatment was measured by VAS, NDI and MENQOL scores of before and after 30 days to start treatment. Results: Both group A and B represented effective improvement in VAS and NDI of neck pain and MENQOL scores. And group A was more effective than B group statistically. Conclusions: It was suggested that Carthami-Flos Pharmacopuncture treatment might have effect on posterior neck pain treatment of menopausal women. I This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited Korean Pharmacopuncture institute Corresponding Author Eun-Yong Lee, Department of Acupuncture & Moxibustion, Semyung University oriental medicine hospital, Bongbang-Dong 836, Chungju , Korea Tel: acupley@semyung.ac.kr.

2 72 Journal of Pharmacopuncture (Carthami-Flos CF) CF CF II (Group A) 10 (Group B) Korea 3 3 (8, 0.45, 0.2

3 Syringe 1 Syringe(1.0, 26gauge Korea) 0.30mm 40mm 10-30mm (Visual analog scale, VAS) (Group A A ) (GB20) (GB21) CF (GV16) (GV14) (BL11)(BL10)(GB20)(GB21) (SI11) Group B B (GV16)(GV14)(BL11)(BL10) (GB20)(GB21)(SI11) Neck Disability index (NDI) NDI Menopause-specific quality of life questionnaire (MENQOL) The menopause-specific quality of life questionnaire(menqol) Hildich 1992 Kupperman's index 5.4 Hot pack, TENS, ICT Vasomotor - 1~33 Psychosocial 4~107 Physical - 11~26(16 Sexual - 27~293 MENQOL (Subscale) subscale overall subscale score overall subscale score

4 74 Journal of Pharmacopuncture A B30 VAS, NDI MENQOL VAS, NDI MEN- QOL Table 1. Distribution of Patients Group A Group B p-value Mean Age Mean Days after on set ) ) ) ) ) ) Duration of 0 3(30.0) 3(30.0) 7 menopause 1-2 3(30.0) 4(40.0) ) SPSS(Statistical program for Social Science) Ver 12.0 for window Mann- Whitney U-test (Pearson`s chisquare test) Wilcoxon signed rank test 0.05 (yr) 3-5 4(40.0) 3(30.0) Group B: Common 1): Mean standard deviation 2): Pearson`s chi-squared test (Table 1) III A B A 3 (30.0%) (30.0%) 3-54 (40.0%) B 3 (20.0%) (40.0%) (30.0%) (Table 1) VAS, NDI, MENQOL 30 VAS, NDI, MENQOL A Z-score VAS NDI , MENQOL B Z- score VAS , NDI , MEN- QOL VAS, NDI, MENQOL (Table 2, Fig. 1-3) Table 2. The Change of VAS, NDI and MENQOL in Each Group Group A 1) Group B 1) VAS NDI MENQOL ** ** ** ** ** ** Group B: Common 1): Z-score in Wilcoxon signed rank test ** : Wilcoxon signed rank test p 0.05

5 VAS, NDI, MENQOL 30 VAS P-value 0.029, NDI 0.007, MEN- QOL (Table 3, Fig. 4, 5) Fig. 1. The Change of VAS on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture Group B: Common ** : Wilcoxon signed rank test p 0.05 Table 3. Comparisoin of VAS, NDI and MENQOL Improvement VAS Group A 1) Group B 1) p-value * NDI ** MENQOL *** Group B: Common 1) Mean standard deviation * : Mann-Whitney U-test p 0.05 ** : Mann-Whitney U-test p 0.01 *** : Mann-Whitney U-test p Fig. 2. The Change of NDI on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture Group B: Common ** : Wilcoxon signed rank test p 0.05 Fig. 4. Comparisoin of VAS and NDI Improvement on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture Group B: Common * : Mann-Whitney U-test p 0.05 ** : Mann-Whitney U-test p 0.01 Fig. 3. The Change of MENQOL on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture Group B: Common ** : Wilcoxon signed rank test p 0.05

6 76 Journal of Pharmacopuncture Fig. 5. Comparisoin of MENQOL Improvement on Posterior Neck pain of Menopausal Women treated by Carthami-Flos Pharmacopuncture and Common acupuncture Group B: Common *** : Mann-Whitney U-test p IV 3-6 (Cervical spondylosis)

7 77 Carthami-Flos CF CF (GB20) (GB21) CF CF 10 A 10 B A B A 4 (40.0%) 3 (30.0%) 3 (30.0%) B 2 (20.0%) 3 (30.0%) 1 (10.0%) 1 (10.0%) 3 (30.0%) (Table 1) A VAS, NDI, MEN- QOL Z-score , , , B VAS, NDI, MENQOL Z-score , , (Table 2, Fig. 1-3) A B VAS P-value 0.029, NDI 0.007, MENQOL (Table 3, Fig. 4, 5) CF CF CF V CF 10 A 10 B 1. (VAS), Neck Disability index (NDI) Menopause-specific quality of life questionnaire (MENQOL) A B 2. A B A B References 1. Lee JH et al. A Study on Climacteric Symptoms in Korean Midlife Women. The Journal of Korean menopause. 2000; 6(2): Lee JA et al. Relation of Lifestyle Factors to Menopausal Symptoms and Management of Middle-aged Women in Rural Area. The Journal of Korean Maternal and Child Health.

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