Anatomical Substrates of Somatic Sensation
|
|
|
- Dora Marshall
- 6 years ago
- Views:
Transcription
1 Anatomical Substrates of Somatic Sensation John H. Martin, Ph.D. Center for Neurobiology & Behavior Columbia University CPS The 2 principal somatic sensory systems: 1) Dorsal column-medial lemniscal system 2) Anterolateral system Dorsal Column-Medial Lemniscal System Mediates mechanical sensations -touch, limb position sense, vibration sense Well established; clinical & experimental
2 Anterolateral System Mediates protective sensations -Pain -Temperature (cold & warmth) -Itch Not as definitively established as is the DC-ML system for touch Why? Pain w/o tissue trauma Trauma w/o pain Cultural; pathological Perspective: Peripheral somatic sensory receptors are sensitive to different stimulus qualities Mechanical Thermal (warm, cold) Noxious (mechanical, thermal, polymodal) Different receptor classes provide input to different somatic sensory pathways Differential thalamic and cortical localization Dorsal columnmedial lemniscal system: Mechanical sensations 3. Thalamus: Ventral posterior nucleus 1 somatic sensory cortex Medial lemniscus Dorsal column Peripheral nerve 2. Dorsal column nuclei 1. Mechanoreceptor Dorsal root ganglion
3 Anterolateral system: Pain, Thermal, Itch 3. Thalamus: Ventral posterior & Medial dorsal nuclei. Cingulate cortex 1 somatic sensory cortex Insular cortex Peripheral axon 1. Nociceptor Thermoreceptor Itch/histamine Dorsal root ganglion Dorsal horn 2. Anterolateral system: Spinothalamic tract Spinoreticular tract Spinomesencephalic tract Mechanoreceptors are encapsulated Meissner s corpuscle Merkel s receptor Pacinian corpuscle Nociceptors, thermoreceptors, & itch receptors are bare nerve endings Bare nerve ending Meissner s corpuscle Merkel s receptor Pacinian corpuscle
4 Dorsal root ganglion neuron PNS CNS Receptive Conductive - 1 afferent fiber Integrative Output Key Characteristics of DRG Neurons Peripheral receptive field Spatial area within which stimulation activates the sensory neuron Receptive field
5 CNS Neurons have Receptive Fields Key Characteristics of DRG Neurons Peripheral receptive field Spatial area within which stimulation activates the sensory neuron Response to constant stimulation Slow adaptation Rapid adaptation Off On Mechanoreceptor receptive fields Rapidly adapting Meissner's Slowly adapting Merkel Pacinian Ruffini
6 Mechanoreceptor receptive fields Rapidly adapting Meissner's Slowly adapting Merkel Pacinian Ruffini Nociceptors, thermoreceptors, & itch receptors are bare nerve endings Bare nerve ending Meissner s corpuscle Merkel s receptor Pacinian corpuscle Nociceptors respond to noxious stimuli Blunt probe High force; NOT NOXIOUS; NO RESPONSE Pin Low force; NOXIOUS; RESPONSE Serrated forceps Low force; VERY NOXIOUS; LARGE RESPONSE
7 Peripheral nerve cross section Unmyelinated Small myelinated Large myelinated Fiber Histogram: Sensory axon innervating the skin IV (C) III (A-δ) II (A-β) Fiber Histogram: Sensory axon innervating a muscle Protective IV (C) III (A-δ) Mechanoreceptors I (A-α) II (A-β)
8 Sensory Dorsal root Motor Ventral root Spinal nerve Dermatomes Area of skin innervated by all sensory fibers w/in single dorsal root Dermatomes overlap Skin Dermatome facts: Pain dermatomes overlap < touch Dermatomal boundaries vary Peripheral nerve Dorsal root Ventral root
9 Dermatomes overlap Skin Peripheral nerve Dorsal root Ventral root Dermatomes overlap Skin Peripheral nerve Dorsal root Ventral root Lateral column Anterolateral column Ventral column Dorsal column Dorsal root ganglion Dorsal root Dorsal horn Intermediate zone Ventral horn Ventral root Spinal nerve
10 Dorsal columnmedial lemniscal system Meissner s corpuscle Anterolateral system Bare nerve ending Merkel s receptor Pacinian corpuscle Reminder: Rexed s laminae Somatotopic organization of the dorsal columns Rostral Demyelination Caudal
11 Lamina 5 Lamina 5
12 Spinal Hemisection Ipsilateral loss of touch Contralateral loss of pain (2-3 segments caudal to injury) Mechanoreceptor Nociceptor Syringomyelia Bilateral loss of pain & thermal senses Preservation of mechanosensations Site of lesion Somatotopy of spinal paths
13 Postcentral gyrus / Insular/ Cingulate cortex Anterolateral system Dorsal columnmedial lemniscal system Postcentral gyrus / 1 SScx Also: Reticular formation Superior colliculus (mesencephalon) Spinal commissure Pain, thermal, itch Dorsal horn Internal arcuate fibers Dorsal column nuclei Mechano Somatic Sensory Thalamus Medial dorsal Ventral posterior medial-vpm (trigem) Ventral posterior lateral-vpl (spinal) Touch Ventral posterior (VMpo) Pain Leg area Arm area Face area Internal capsule Ventral posterior nucleus
14 1 Visual Cortex Cell-stained section (Nissl) most 6 cell layers Layer 1 Layers 2 & 3 Layer 4 Layer 5 Layer 6 neuron density varies Brodmann s cytoarchitectonic areas Over 50 areas Defined on basis of histology Somatic sensory areas: 1 somatic sen. cx = 1, 2, 3a, 3b
15 Somatic Sensory Cortical Areas for Mechanosensations 1 somatic sensory cortex Area 5 (3 SScx) Area 7 (Posterior Parietal cortex) Central Skin Postcentral sulcusreceptors gyrus Postcentral sulcus 2 somatic sensory cortex Deep receptors Pyramidal neuron: projection neuron Layer 1 Layers 2 & 3 Stellate Neuron: interneuron Layer 4 Layer 5 Layer 6 from Thalamus back to Thalamus to Subcortical areas to Other cortical areas 1 Somatic Sensory Cortex Output Systems VP lateral VP medial Mechanosensation
16 Cortical Pain Representations Thalamus Cortex Behavior Medial dorsal Anterior cingulate Emotional/salience/ valence Ventral med. Post. (VM po) Mid-insular cortex Limbic cortex Amygdala Behavioral Autonomic Ventral posterior (VPL/VPM) 1 SS Cortex??Localization/ Discrimination Cingulate gyrus: emotional/valence Postcentral gyrus: localization Insular pain representation: behavioral (autonomic; react) Summary Early morphological specialization of DRG neurons sets stage for separate mechanosensory and pain/temp/itch systems Different ascending pathways to distinct subcortical and cortical sites Single thalamic mechanosensory nucleus and 1 ctx Multiple thalamic pain nuclei and cortical areas Parietal lobe projections may play role in stimulus localization, esp. for touch Cortical pain representations closely tied to emotions
Mechanosensation. Central Representation of Touch. Wilder Penfield. Somatotopic Organization
Mechanosensation Central Representation of Touch Touch and tactile exploration Vibration and pressure sensations; important for clinical testing Limb position sense John H. Martin, Ph.D. Center for Neurobiology
Medical Neuroscience Tutorial
Pain Pathways Medical Neuroscience Tutorial Pain Pathways MAP TO NEUROSCIENCE CORE CONCEPTS 1 NCC1. The brain is the body's most complex organ. NCC3. Genetically determined circuits are the foundation
Somatic Sensation (MCB160 Lecture by Mu-ming Poo, Friday March 9, 2007)
Somatic Sensation (MCB160 Lecture by Mu-ming Poo, Friday March 9, 2007) Introduction Adrian s work on sensory coding Spinal cord and dorsal root ganglia Four somatic sense modalities Touch Mechanoreceptors
Posterior White Column-Medial Lemniscal Pathway
Posterior White Column-Medial Lemniscal Pathway Modality: Discriminative Touch Sensation (include Vibration) and Conscious Proprioception Receptor: Most receptors except free nerve endings Ist Neuron:
General Sensory Pathways of the Trunk and Limbs
General Sensory Pathways of the Trunk and Limbs Lecture Objectives Describe gracile and cuneate tracts and pathways for conscious proprioception, touch, pressure and vibration from the limbs and trunk.
SOMATOSENSORY SYSTEMS: Conscious and Non-Conscious Proprioception Kimberle Jacobs, Ph.D.
SOMATOSENSORY SYSTEMS: Conscious and Non-Conscious Proprioception Kimberle Jacobs, Ph.D. Divisions of Somatosensory Systems The pathways that convey sensory modalities from the body to consciousness are
How strong is it? What is it? Where is it? What must sensory systems encode? 9/8/2010. Spatial Coding: Receptive Fields and Tactile Discrimination
Spatial Coding: Receptive Fields and Tactile Discrimination What must sensory systems encode? How strong is it? What is it? Where is it? When the brain wants to keep certain types of information distinct,
Spatial Coding: Receptive Fields and Tactile Discrimination
Spatial Coding: Receptive Fields and Tactile Discrimination What must sensory systems encode? How strong is it? What is it? Where is it? When the brain wants to keep certain types of information distinct,
SOMATOSENSORY SYSTEMS: Pain and Temperature Kimberle Jacobs, Ph.D.
SOMATOSENSORY SYSTEMS: Pain and Temperature Kimberle Jacobs, Ph.D. Sensory systems are afferent, meaning that they are carrying information from the periphery TOWARD the central nervous system. The somatosensory
SOMATIC SENSATION PART I: ALS ANTEROLATERAL SYSTEM (or SPINOTHALAMIC SYSTEM) FOR PAIN AND TEMPERATURE
Dental Neuroanatomy Thursday, February 3, 2011 Suzanne S. Stensaas, PhD SOMATIC SENSATION PART I: ALS ANTEROLATERAL SYSTEM (or SPINOTHALAMIC SYSTEM) FOR PAIN AND TEMPERATURE Reading: Waxman 26 th ed, :
Pain and Temperature Objectives
Pain and Temperature Objectives 1. Describe the types of sensory receptors that transmit pain and temperature. 2. Understand how axon diameter relates to transmission of pain and temp information. 3. Describe
Somatosensory System. Steven McLoon Department of Neuroscience University of Minnesota
Somatosensory System Steven McLoon Department of Neuroscience University of Minnesota 1 Course News Dr. Riedl s review session this week: Tuesday (Oct 10) 4-5pm in MCB 3-146B 2 Sensory Systems Sensory
Somatic Sensory System I. Background
Somatic Sensory System I. Background A. Differences between somatic senses and other senses 1. Receptors are distributed throughout the body as opposed to being concentrated at small, specialized locations
The Somatosensory System
The Somatosensory System Reading: BCP Chapter 12 cerebrovortex.com Divisions of the Somatosensory System Somatosensory System Exteroceptive External stimuli Proprioceptive Body position Interoceptive Body
CHAPTER 10 THE SOMATOSENSORY SYSTEM
CHAPTER 10 THE SOMATOSENSORY SYSTEM 10.1. SOMATOSENSORY MODALITIES "Somatosensory" is really a catch-all term to designate senses other than vision, hearing, balance, taste and smell. Receptors that could
Sensory coding and somatosensory system
Sensory coding and somatosensory system Sensation and perception Perception is the internal construction of sensation. Perception depends on the individual experience. Three common steps in all senses
Skin types: hairy and glabrous (e.g. back vs. palm of hand)
Lecture 19 revised 03/10 The Somatic Sensory System Skin- the largest sensory organ we have Also protects from evaporation, infection. Skin types: hairy and glabrous (e.g. back vs. palm of hand) 2 major
Somatosensation. Recording somatosensory responses. Receptive field response to pressure
Somatosensation Mechanoreceptors that respond to touch/pressure on the surface of the body. Sensory nerve responds propotional to pressure 4 types of mechanoreceptors: Meissner corpuscles & Merkel discs
Unit VIII Problem 1 Physiology: Sensory Pathway
Unit VIII Problem 1 Physiology: Sensory Pathway - Process of sensation: Sensory receptors: they are specialized cells considered as biologic signal transducers which can detect stimuli and convert them
Ch. 47 Somatic Sensations: Tactile and Position Senses (Reading Homework) - Somatic senses: three types (1) Mechanoreceptive somatic senses: tactile
Ch. 47 Somatic Sensations: Tactile and Position Senses (Reading Homework) - Somatic senses: three types (1) Mechanoreceptive somatic senses: tactile and position sensations (2) Thermoreceptive senses:
Pathways of proprioception
The Autonomic Nervous Assess Prof. Fawzia Al-Rouq Department of Physiology College of Medicine King Saud University Pathways of proprioception System posterior column& Spinocerebellar Pathways https://www.youtube.com/watch?v=pmeropok6v8
Psychophysical laws. Legge di Fechner: I=K*log(S/S 0 )
Psychophysical laws Legge di Weber: ΔS=K*S Legge di Fechner: I=K*log(S/S 0 ) Sensory receptors Vision Smell Taste Touch Thermal senses Pain Hearing Balance Proprioception Sensory receptors Table 21-1 Classification
Lecturer. Prof. Dr. Ali K. Al-Shalchy MBChB/ FIBMS/ MRCS/ FRCS 2014
Lecturer Prof. Dr. Ali K. Al-Shalchy MBChB/ FIBMS/ MRCS/ FRCS 2014 Dorsal root: The dorsal root carries both myelinated and unmyelinated afferent fibers to the spinal cord. Posterior gray column: Long
Chapter 15! Chapter 15 Sensory Pathways, Somatic Nervous System! Neural Integration I: Sensory Pathways and the Somatic Nervous System!
Chapter 15! Neural Integration I: Sensory Pathways and the SECTION 15-2! Sensory receptors connect our internal and external environments with the nervous system! 2 Sensation and Receptors! Transduction!
Biology 218 Human Anatomy
Chapter 21 Adapted form Tortora 10 th ed. LECTURE OUTLINE A. Overview of Sensations (p. 652) 1. Sensation is the conscious or subconscious awareness of external or internal stimuli. 2. For a sensation
Our senses provide us with wonderful capabilities. If you had to lose one, which would it be?
Our senses provide us with wonderful capabilities. If you had to lose one, which would it be? Neurological disorders take away sensation without a choice! http://neuroscience.uth.tmc.edu/s2/chapter04.html
1. Somatosensory Pathways
1. Somatosensory Pathways Objectives 1. Describe the general characteristics of sensory pathways 2. Understand the general organization and numbered areas of spinal cord gray matter 3. Understand dermatomes
Department of Neurology/Division of Anatomical Sciences
Spinal Cord I Lecture Outline and Objectives CNS/Head and Neck Sequence TOPIC: FACULTY: THE SPINAL CORD AND SPINAL NERVES, Part I Department of Neurology/Division of Anatomical Sciences LECTURE: Monday,
Chapter 14: Integration of Nervous System Functions I. Sensation.
Chapter 14: Integration of Nervous System Functions I. Sensation A. General Organization 1. General senses have receptors a. The somatic senses provide information about & 1. Somatic senses include: a.
Note: Waxman is very sketchy on today s pathways and nonexistent on the Trigeminal.
Dental Neuroanatomy Thursday, February 3, 2011 Suzanne Stensaas, PhD Note: Waxman is very sketchy on today s pathways and nonexistent on the Trigeminal. Resources: Pathway Quiz for HyperBrain Ch. 5 and
SOMATOSENSORY SYSTEMS
SOMATOSENSORY SYSTEMS Schematic diagram illustrating the neural pathways that convey somatosensory information to the cortex and, subsequently, to the motor system. Double arrows show reciprocal connections.
Neural Integration I: Sensory Pathways and the Somatic Nervous System
15 Neural Integration I: Sensory Pathways and the Somatic Nervous System PowerPoint Lecture Presentations prepared by Jason LaPres Lone Star College North Harris An Introduction to Sensory Pathways and
Sensory information processing, somato-sensory systems
mm? Sensory information processing, somato-sensory systems Recommended literature 1. Kandel ER, Schwartz JH, Jessel TM (2000) Principles of Neural Science, McGraw-Hill, Ch. xx. 2. Berne EM, Levy MN, Koeppen
Chapter 16: Sensory, Motor, and Integrative Systems. Copyright 2009, John Wiley & Sons, Inc.
Chapter 16: Sensory, Motor, and Integrative Systems Sensation n Conscious and subconscious awareness of changes in the external or internal environment. n Components of sensation: Stimulation of the sensory
The Nervous System: Sensory and Motor Tracts of the Spinal Cord
15 The Nervous System: Sensory and Motor Tracts of the Spinal Cord PowerPoint Lecture Presentations prepared by Steven Bassett Southeast Community College Lincoln, Nebraska Introduction Millions of sensory
Pain classifications slow and fast
Pain classifications slow and fast Fast Pain Slow Pain Sharp, pricking (Aδ) fiber Short latency Well localized Short duration Dull, burning (C) fiber Slower onset Diffuse Long duration Less emotional Emotional,
Bi/CNS/NB 150: Neuroscience. November 11, 2015 SOMATOSENSORY SYSTEM. Ralph Adolphs
Bi/CNS/NB 150: Neuroscience November 11, 2015 SOMATOSENSORY SYSTEM Ralph Adolphs 1 Menu for today Touch -peripheral -central -plasticity Pain 2 Sherrington (1948): senses classified as --teloreceptive
*Anteriolateral spinothalamic tract (STT) : a sensory pathway that is positioned anteriorly and laterally in the spinal cord.
*somatic sensations : PAIN *Anteriolateral spinothalamic tract (STT) : a sensory pathway that is positioned anteriorly and laterally in the spinal cord. *This pathway carries a variety of sensory modalities:
IV. THE SPINAL CORD BLOOD SUPPLY
IV. THE SPINAL CORD Spinal cord is covered by o Pia Mater Spinalis Film Teminale Denticulate Ligament ---------------------- Cordotomy o Arachnoid Membrane Subarachnoid Space ----------------------- Lumbar
THE SOMATOSENSORY SYSTEM
Daniel J. Simons, Ph.D. I. Peripheral Nervous System THE SOMATOSENSORY SYSTEM The somatosensory system consists of those components of the peripheral and central nervous systems that mediate sensations
Auditory and Vestibular Systems
Auditory and Vestibular Systems Objective To learn the functional organization of the auditory and vestibular systems To understand how one can use changes in auditory function following injury to localize
Collin County Community College. BIOL 2401 : Anatomy/ Physiology PNS
Collin County Community College BIOL 2401 : Anatomy/ Physiology PNS Peripheral Nervous System (PNS) PNS all neural structures outside the brain and spinal cord Includes sensory receptors, peripheral nerves,
Thalamus and Sensory Functions of Cerebral Cortex
Thalamus and Sensory Functions of Cerebral Cortex I: To describe the functional divisions of thalamus. II: To state the functions of thalamus and the thalamic syndrome. III: To define the somatic sensory
SENSORY (ASCENDING) SPINAL TRACTS
SENSORY (ASCENDING) SPINAL TRACTS Dr. Jamila El-Medany Dr. Essam Eldin Salama OBJECTIVES By the end of the lecture, the student will be able to: Define the meaning of a tract. Distinguish between the different
Laurie L. Wellman Ph.D.
Laurie L. Wellman Ph.D. Theodore Tzavaras MD2015 Eastern Virginia Medical School Dr. Craig Goodmurphy Anatomy Guy 1. Discuss -- what is pain? 2. Outline the Anterolateral Quadrant (ALQ) pathway 3. Locate
Lecture VIII. The Spinal Cord, Reflexes and Brain Pathways!
Reflexes and Brain Bio 3411! Monday!! 1! Readings! NEUROSCIENCE 5 th ed: Review Chapter 1 pp. 11-21;!!Read Chapter 9 pp. 189-194, 198! THE BRAIN ATLAS 3 rd ed:! Read pp. 4-17 on class web site! Look at
Anatomy of the Spinal Cord
Spinal Cord Anatomy of the Spinal Cord Anatomy of the Spinal Cord Posterior spinal arteries Lateral corticospinal tract Dorsal column Spinothalamic tract Anterior spinal artery Anterior white commissure
OVERVIEW. Today. Sensory and Motor Neurons. Thursday. Parkinsons Disease. Administra7on. Exam One Bonus Points Slides Online
OVERVIEW Today Sensory and Motor Neurons Thursday Parkinsons Disease Administra7on Exam One Bonus Points Slides Online 7 major descending motor control pathways from Cerebral Cortex or Brainstem
Spinal Cord Tracts DESCENDING SPINAL TRACTS: Are concerned with somatic motor function, modification of ms. tone, visceral innervation, segmental reflexes. Main tracts arise form cerebral cortex and others
Cortical Control of Movement
Strick Lecture 2 March 24, 2006 Page 1 Cortical Control of Movement Four parts of this lecture: I) Anatomical Framework, II) Physiological Framework, III) Primary Motor Cortex Function and IV) Premotor
Chapter 12b. Overview
Chapter 12b Spinal Cord Overview Spinal cord gross anatomy Spinal meninges Sectional anatomy Sensory pathways Motor pathways Spinal cord pathologies 1 The Adult Spinal Cord About 18 inches (45 cm) long
Chapter 16. Sense of Pain
Chapter 16 Sense of Pain Pain Discomfort caused by tissue injury or noxious stimulation, and typically leading to evasive action important /// helps to protect us lost of pain in diabetes mellitus = diabetic
III: To define the mechanoreceptive and thermoreceptive sensations.
Somatic Sensations I: To explain the proper way of sensory testing. II: To describe the somatic sensations. III: To define the mechanoreceptive and thermoreceptive sensations. SOMATIC SENSATIONS Somatic
Spinal Cord Organization. January 12, 2011
Spinal Cord Organization January 12, 2011 Spinal Cord 31 segments terminates at L1-L2 special components - conus medullaris - cauda equina no input from the face Spinal Cord, Roots & Nerves Dorsal root
CHAPTER 16: SENSORY, MOTOR, & INTEGRATIVE SYSTEM DR. WELCH
BIOL 2401 DR. WELCH CHAPTER 16: SENSORY, MOTOR, & INTEGRATIVE SYSTEM I. Sensation conscious or subconscious awareness of internal & external changes. Define perception. Primary function of. Why isn t blood
PAIN IS A SUBJECTIVE EXPERIENCE: It is not a stimulus. MAJOR FEATURES OF THE PAIN EXPERIENCE: Sensory discriminative Affective (emotional) Cognitive
PAIN PAIN IS A SUBJECTIVE EXPERIENCE: It is not a stimulus MAJOR FEATURES OF THE PAIN EXPERIENCE: Sensory discriminative Affective (emotional) Cognitive MEASUREMENT OF PAIN: A BIG PROBLEM Worst pain ever
SOMATOSENSORY SYSTEMS AND PAIN
SOMATOSENSORY SYSTEMS AND PAIN A 21 year old man presented with a stab wound of the right side of the neck (Panel A). Neurological examination revealed right hemiplegia and complete right-sided loss of
1. Which part of the brain is responsible for planning and initiating movements?
Section: Chapter 10: Multiple Choice 1. Which part of the brain is responsible for planning and initiating movements? p.358 frontal lobe hippocampus basal ganglia cerebellum 2. The prefrontal cortex is
Meninges. Connective tissue membranes
Meninges Connective tissue membranes Dura mater: -outermost layer; continuous with epineuriumof the spinal nerves - dense irregular connective tissue - from the level of the foramen magnum to S2 Arachnoid
CHAPTER 16 LECTURE OUTLINE
CHAPTER 16 LECTURE OUTLINE I. INTRODUCTION A. The components of the brain interact to receive sensory input, integrate and store the information, and transmit motor responses. B. To accomplish the primary
Neural Integration I: Sensory Pathways and the Somatic Nervous System
C h a p t e r 15 Neural Integration I: Sensory Pathways and the Somatic Nervous System PowerPoint Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright 2009 Pearson Education,
The Motor Systems. What s the motor system? Plan
The Motor Systems What s the motor system? Parts of CNS and PNS specialized for control of limb, trunk, and eye movements Also holds us together From simple reflexes (knee jerk) to voluntary movements
PETER PAZMANY CATHOLIC UNIVERSITY Consortium members SEMMELWEIS UNIVERSITY, DIALOG CAMPUS PUBLISHER
PETER PAZMANY CATHOLIC UNIVERSITY SEMMELWEIS UNIVERSITY Development of Complex Curricula for Molecular Bionics and Infobionics Programs within a consortial* framework** Consortium leader PETER PAZMANY
Coding of Sensory Information
Coding of Sensory Information 22 November, 2016 Touqeer Ahmed PhD Atta-ur-Rahman School of Applied Biosciences National University of Sciences and Technology Sensory Systems Mediate Four Attributes of
Fig Cervical spinal nerves. Cervical enlargement C7. Dural sheath. Subarachnoid space. Thoracic. Spinal cord Vertebra (cut) spinal nerves
Fig. 13.1 C1 Cervical enlargement C7 Cervical spinal nerves Dural sheath Subarachnoid space Thoracic spinal nerves Spinal cord Vertebra (cut) Lumbar enlargement Medullary cone T12 Spinal nerve Spinal nerve
What is Pain? An unpleasant sensory and emotional experience associated with actual or potential tissue damage. Pain is always subjective
Pain & Acupuncture What is Pain? An unpleasant sensory and emotional experience associated with actual or potential tissue damage. NOCICEPTION( the neural processes of encoding and processing noxious stimuli.)
4. Sensory Systems. 4.1 Receptors. - cutaneous receptors: on the body surface and accessible mucous membranes
4. Sensory Systems The term 'sensory systems' applies to those parts of the nervous system concerned with the detection, transmission and analysis of information about stimuli from the internal and external
Last time we talked about the descending pathways of pain and the ALS. Today we will continue talking about these descending pathways.
Last time we talked about the descending pathways of pain and the ALS. Today we will continue talking about these descending pathways. Each higher level will control the level under It. In controlling
UNIVERSITY OF JORDAN FACULTY OF MEDICINE DEPARTMENT OF PHYSIOLOGY & BIOCHEMISTRY NEUROPHYSIOLOGY (MEDICAL), SPRING 2014
UNIVERSITY OF JORDAN FACULTY OF MEDICINE DEPARTMENT OF PHYSIOLOGY & BIOCHEMISTRY NEUROPHYSIOLOGY (MEDICAL), SPRING 2014 Textbook of Medical Physiology by: Guyton & Hall, 12 th edition 2011 Eman Al-Khateeb,
Chapter 6. Gathering information; the sensory systems
Chapter 6 Gathering information; the sensory systems Gathering information the sensory systems The parts of the nervous system that receive and process information are termed sensory systems. There are
COGS 107B Week 1. Hyun Ji Friday 4:00-4:50pm
COGS 107B Week 1 Hyun Ji Friday 4:00-4:50pm Before We Begin... Hyun Ji 4th year Cognitive Behavioral Neuroscience Email: hji@ucsd.edu In subject, always add [COGS107B] Office hours: Wednesdays, 3-4pm in
San Francisco Chronicle, June 2001
PAIN San Francisco Chronicle, June 2001 CONGENITAL INSENSITIVITY TO PAIN PAIN IS A SUBJECTIVE EXPERIENCE: It is not a stimulus MAJOR FEATURES OF THE PAIN EXPERIENCE: Sensory discriminative Affective (emotional)
Neuronal Circuits and Neuronal Pools
Neuronal Circuits and Neuronal Pools Anatomical Orientation Clinical Orientation Atlas Fig. 6-24 The Reality of the Clinical Environment Atlas Fig. 6-24A One Cardinal Plane to Learn AND Understand
Chapter 13 PNS and reflex activity
Chapter 13 PNS and reflex activity I. Peripheral nervous system A. PNS links CNS to the body B. Sensory: the afferent division C. Motor: the efferent division D. Ganglia: collections of cell bodies in
Overview of Questions
Overview of Questions What are the sensors in the skin, what do they respond to and how is this transmitted to the brain? How does the brain represent touch information? What is the system for sensing
Receptors and Neurotransmitters: It Sounds Greek to Me. Agenda. What We Know About Pain 9/7/2012
Receptors and Neurotransmitters: It Sounds Greek to Me Cathy Carlson, PhD, RN Northern Illinois University Agenda We will be going through this lecture on basic pain physiology using analogies, mnemonics,
Physiology of Tactile Sensation
Physiology of Tactile Sensation Objectives: 1. Describe the general structural features of tactile sensory receptors how are first order nerve fibers specialized to receive tactile stimuli? 2. Understand
Chapter 14: The Cutaneous Senses
Chapter 14: The Cutaneous Senses Somatosensory System There are three parts Cutaneous senses - perception of touch and pain from stimulation of the skin Proprioception - ability to sense position of the
P. Hitchcock, Ph.D. Department of Cell and Developmental Biology Kellogg Eye Center. Wednesday, 16 March 2009, 1:00p.m. 2:00p.m.
Normal CNS, Special Senses, Head and Neck TOPIC: CEREBRAL HEMISPHERES FACULTY: LECTURE: READING: P. Hitchcock, Ph.D. Department of Cell and Developmental Biology Kellogg Eye Center Wednesday, 16 March
Somatosensory modalities!
Somatosensory modalities! The somatosensory system codes five major sensory modalities:! 1. Discriminative touch! 2. Proprioception (body position and motion)! 3. Nociception (pain and itch)! 4. Temperature!
NS201C Anatomy 1: Sensory and Motor Systems
NS201C Anatomy 1: Sensory and Motor Systems 25th January 2017 Peter Ohara Department of Anatomy peter.ohara@ucsf.edu The Subdivisions and Components of the Central Nervous System Axes and Anatomical Planes
Sensory Pathways & Somatic Nervous System. Chapter 15
Sensory Pathways & Somatic Nervous System Chapter 15 How Does Brain Differentiate Sensations? Pain impulses make brain aware of injuries and infections. Impulses from eye, ear, nose and tongue make brain
The neurvous system senses, interprets, and responds to changes in the environment. Two types of cells makes this possible:
NERVOUS SYSTEM The neurvous system senses, interprets, and responds to changes in the environment. Two types of cells makes this possible: the neuron and the supporting cells ("glial cells"). Neuron Neurons
THE BACK. Dr. Ali Mohsin. Spinal Cord
Spinal Cord THE BACK Dr. Ali Mohsin The spinal cord is the elongated caudal part of the CNS. It starts as the inferior continuation of the medulla oblongata at the level of foramen magnum, & ends as an
NERVOUS SYSTEM. Academic Resource Center. Forskellen mellem oscillator og krystal
NERVOUS SYSTEM Academic Resource Center Forskellen mellem oscillator og krystal Overview of the Nervous System Peripheral nervous system-pns cranial nerves spinal nerves ganglia peripheral nerves enteric
Outline of the next three lectures
Outline of the next three lectures Lecture 35 Anatomy of the human cerebral cortex gross and microscopic cell types connections Vascular supply of the cerebral cortex Disorders involving the cerebral cortex
Systems Neuroscience Dan Kiper. Today: Wolfger von der Behrens
Systems Neuroscience Dan Kiper Today: Wolfger von der Behrens wolfger@ini.ethz.ch 18.9.2018 Neurons Pyramidal neuron by Santiago Ramón y Cajal (1852-1934, Nobel prize with Camillo Golgi in 1906) Neurons
UNIVERSITY OF JORDAN FACULTY OF MEDICINE DEPARTMENT OF PHYSIOLOGY & BIOCHEMISTRY NEUROPHYSIOLOGY (MEDICAL), SPRING 2014
UNIVERSITY OF JORDAN FACULTY OF MEDICINE DEPARTMENT OF PHYSIOLOGY & BIOCHEMISTRY NEUROPHYSIOLOGY (MEDICAL), SPRING 2014 Textbook of Medical Physiology by: Guyton & Hall, 12 th edition 2011 Eman Al-Khateeb,
Motor Functions of Cerebral Cortex
Motor Functions of Cerebral Cortex I: To list the functions of different cortical laminae II: To describe the four motor areas of the cerebral cortex. III: To discuss the functions and dysfunctions of
V1-ophthalmic. V2-maxillary. V3-mandibular. motor
4. Trigeminal Nerve I. Objectives:. Understand the types of sensory information transmitted by the trigeminal system.. Describe the major peripheral divisions of the trigeminal nerve and how they innervate
Introduction to the Nervous System. Code: HMP 100/ UPC 103/ VNP 100. Course: Medical Physiology. Level 1 MBChB/BDS/BPharm
Introduction to the Nervous System. Code: HMP 100/ UPC 103/ VNP 100. Course: Medical Physiology Level 1 MBChB/BDS/BPharm Lecture 2. Functional Organisation of the Nervous System Lecture Outline 1.1 Introduction
The anatomy and physiology of pain
The anatomy and physiology of pain Charlotte E Steeds Abstract Pain is an unpleasant experience that results from both physical and psychological responses to injury. A complex set of pathways transmits
ANAT2010. Concepts of Neuroanatomy (II) S2 2018
ANAT2010 Concepts of Neuroanatomy (II) S2 2018 Table of Contents Lecture 13: Pain and perception... 3 Lecture 14: Sensory systems and visual pathways... 11 Lecture 15: Techniques in Neuroanatomy I in vivo
Homework Week 2. PreLab 2 HW #2 Synapses (Page 1 in the HW Section)
Homework Week 2 Due in Lab PreLab 2 HW #2 Synapses (Page 1 in the HW Section) Reminders No class next Monday Quiz 1 is @ 5:30pm on Tuesday, 1/22/13 Study guide posted under Study Aids section of website
Lecture - Chapter 13: Central Nervous System
Lecture - Chapter 13: Central Nervous System 1. Describe the following structures of the brain, what is the general function of each: a. Cerebrum b. Diencephalon c. Brain Stem d. Cerebellum 2. What structures
Autonomic Nervous System, Visceral Sensation and Visceral Reflexes Jeff Dupree, Ph.D.
Autonomic Nervous System, Visceral Sensation and Visceral Reflexes Jeff Dupree, Ph.D. OBJECTIVES After studying the material of this lecture, the student should know the: 1. basic divisions of the autonomic
Prof. Saeed Abuel Makarem & Dr.Sanaa Alshaarawy
Prof. Saeed Abuel Makarem & Dr.Sanaa Alshaarawy 1 Objectives By the end of the lecture, you should be able to: Describe the anatomy and main functions of the thalamus. Name and identify different nuclei
General Sensory Pathways of the Face Area, Taste Pathways and Hearing Pathways
General Sensory Pathways of the Face Area, Taste Pathways and Hearing Pathways Lecture Objectives Describe pathways for general sensations (pain, temperature, touch and proprioception) from the face area.
Brainstem. Steven McLoon Department of Neuroscience University of Minnesota
Brainstem Steven McLoon Department of Neuroscience University of Minnesota 1 Course News Change in Lab Sequence Week of Oct 2 Lab 5 Week of Oct 9 Lab 4 2 Goal Today Know the regions of the brainstem. Know
16. which is not synthesised in postganglionic sympathetic neurons a. L-dopa b. DA c. NA d. A e. ACh
NERVOUS SYSTEM 1. Visual pathways a. Have P cells that are associated with colour b. Utilize the primary colours, red, yellow and blue c. Have simple cells which respond to all light stimuli d. Pass through