APPLICATIONS OF LOW LEVEL LASER THERAPY IN PODIATRY: AN IN-DEPTH LOOK

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3 APPLICATIONS OF LOW LEVEL LASER THERAPY IN PODIATRY: AN IN-DEPTH LOOK

4 Contact Information Richard Silverstein, DPM Division Head Podiatry Section/Department of Surgery University of Maryland Harford Memorial Hospital 807-B South Union Avenue Havre De Grace, MD (410) office (410) cell

5 American Podiatric Medical Association Disclosure The following relationships with commercial interests existed during the past 12 months: Erchonia Corporation Akina Pharmaceuticals

6 Lecture Goals To define what a Cold Laser is To understand the mechanism of action of Cold Lasers To review the current literature supporting Cold Laser therapy To identify how Cold Lasers can be utilized in the podiatric practice

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8 What is a laser anyway? Laser Light Amplification by Stimulated Emission of Radiation Based on the principles of stimulated radiation by Einstein in 1917 Lasers differ from other sources of light in that they emit light coherently This spatial coherence allows lasers to be focused to a tight spot or beam

9 Cold Laser Therapy (aka Low Level Laser Therapy or LLLT) A form of medicine that uses low-level lasers or light-emitting diodes (LEDs). Other names include low-power laser, soft laser, cold laser, bio stimulation laser, therapeutic laser, and laser acupuncture nm on the em spectrum

10 Characteristics of Low Level Laser Therapy Accelerates cell growth & tissue repair Accelerates fibroblast & collagen production for faster wound healing Reduces inflammation Reduces scar tissue formation Reduces pain & acts as an analgesic

11 Characteristics of Low Level Laser Therapy Cont d. Induces angiogenesis Induces neurogenesis Stimulates an increase in intracellular energy Stimulates a cascade of physiologic effects to promote repair, regeneration & restoration of function

12 What can we do with LLLT?

13 Lower Extremity Relevant Applications of LLLT Acute Inflammatory Conditions Chronic tendon or ligament injury (plantar fasciitis) Chronic pain Osteoarthritis Complex regional pain syndrome Entrapment neuropathy Peripheral neuropathy Neuroma Neuritis Lymphedema Wound healing Fracture healing Eradicate dermatophyte infections

14 Lower Extremity Relevant Applications of LLLT Reverse tendinopathy Reverse plantar fasciosis Reverse plantar plate derangement, a degenerative capsulopathy Non-invasive treatment of chronic tendinopathy, capsulopathy & fasciopathy Enhance angiogenic response in repair of compromised and degenerative tissues Pain control Restoration of function

15 Effects of Low Level Laser Therapy Shortens the inflammatory phase Accelerates the repair process Stimulates tissue regeneration after injury Additionally increases plasma concentrations of prostaglandins, enkephalins and endorphins all playing a role in pain management

16 What is the mechanism of action of low level laser therapy? PHOTOBIOMODULATION

17 How deep do cold lasers penetrate?

18 How do we treat these conditions PRIOR to laser therapy? Educate the patient Dispense durable medical devices and utilize taping Recommend stretches and exercises to promote mobility Limit high impact exercises, recommend modifications at the work place Encourage disease management Prescribe NSAIDS Give steroid injections Recommend laser therapy Recommend surgical management

19 What does the research show? ARTICLE #1

20 The Study: 69 subjects enrolled in a placebo-controlled, randomized, double-blind study. 37 randomized to the active treatment group 32 were placed into the placebo group Treatment group treated twice a week for 3 weeks utilizing LLLT and were evaluated at 6 different time points. Utilized a 635 nm low level laser for treatment

21 Parameters Studied: Pain rating was recorded using a visual analog pain scale. Doppler ultrasonography performed to measure fascial thickness pre and post treatment. Study participants also completed the Foot Function Index.

22 Results:

23 Results:

24 Results:

25 Analog Pain Scale

26 Peripheral Neuropathy and Low Level Laser Therapy What does it mean? Large Nerve Fibers vs Small Nerve Fibers Common Causes: - Diabetes Mellitus Types I and II - Metabolic Syndrome - Idiopathic / familial - Alcohol Abuse - HIV - Pharmacologic toxins / Chemotherapeutic agents

27 Clinical Presentation: Small Fiber Neuropathy Stocking and glove distribution Early hyperesthesia and pain, late hypoesthesia and numbness Pain is burning, superficial Impaired thermal and pain thresholds Decreased sweating Normal strength, reflexes and EMG

28 Diagnosis: Epidermal Nerve Density Small C-fibers and A- delta fibers Established normative value based on body site Objective way to quantify and monitor neuropathy

29 1 NORMAL SMALL FIBER NEUROPATHY Site Result Value Abnormal Low Normal Rt Foot 1.16 < Lt Foot 1.33 Rt Calf 3.62 < Lt Calf 2.88

30 Before Laser: Right Foot: 1.16 After Laser: Right Foot: 4.91

31 Before Laser: Left Foot: 1.33 After Laser: Left Foot: 4.37

32 Having Confidence in the Science

33 Why incorporate Cold Laser treatment modalities into your practice? It is a safe and effective treatment to provide to patients in pain. Incorporates the newest technology into our practice. Garner respect from patients and referring colleagues for being on top of the current trends and effective medical treatments. Safe to use in our diabetic patients and vascularly compromised patients.

34 Marketing the Laser Brochures and patient education Use your EMR to your advantage, you paid enough for it! Enhance your web site and direct your patients there Radio advertising ROI and pressure

35 Bibliography Can LLLT have an impact for Small Fiber Neuropathy? Podiatry Today, volume 24, issue 6, June 2011, Kerry Zang, DPM, Janna Kroleski, DPM, Shahram Askari, DPM, and Sanford Kaner, DPM Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring Seminars in Cutaneous Medicine and Surgery, 2013 March; 32(1): Pinar Avci, Asheesh Gupta, Mgesh Sadasivam, Daniela Vecchio, Zeev Pam, Nadav Pam, Michael Hamblin. The Nuts and Bolts of Low-Level Laser (light) Therapy. Annals of Biomedical engineering, February 2012, Volume 40, Issue 2, pp Hoon Chung, Tianhong Dai, Sulbha K. Sharma, Ying-Ying Huang, James D. Carroll, Michael R. Hamblin, February

36 Bibliography cont d. Low-Level Laser Therapy at 635 nm for Treatment of Chronic Plantar Fasciitis: a Placebo-Controlled Randomized Study The Journal of Foot and Ankle Surgery. Volume 54, Issue 5, September-October, 2015, David M. Macias, MD, Michael J. Coughlin, MD, Kerry Zang, DPM, Faustin R. Stevens, MD, James R. Jastifer, MD, Jesse F. Doty, MD Ultrasonographic evaluation of plantar fasciitis after low-level laser therapy: results of a double-blind, randomized, placebo-controlled trial Lasers in Medical Science. Volume 25, 2010, Olga Kiritsi, Konstantinos Tsitas, Nikolaos Malliaropoulos, Grogorios Mikroulis Low Level Laser Therapy for the Treatment of Chronic Plantar Fasciitis: A Prospective Study. Foot and Ankle International. June 2014;35(6): Jastifer JR, Catena F, Doty JF, Stevens F, Coughlin MF.

37 Nearly all inventions are not recognized for their positive side when they're made. So, for example, scientists didn't go out to design a CD machine: they designed a laser. But we got all sorts of things from a laser which we never remotely imagined, and we're still finding things for a laser to do. Robert Winston

38 THANK YOU!!!