China Human Vaccine Industry Report, July 2017
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1 China Human Vaccine Industry Report, July 2017
2 STUDY GOAL AND OBJECTIVES This report provides the industry executives with strategically significant competitor information, analysis, insight and projection on the competitive pattern and key companies in the industry, crucial to the development and implementation of effective business, marketing and R&D programs. METHODOLOGY Both primary and secondary research methodologies were used in preparing this study. Initially, a comprehensive and exhaustive search of the literature on this industry was conducted. These sources included related books and journals, trade literature, marketing literature, other product/promotional literature, annual reports, security analyst reports, and other publications. REPORT OBJECTIVES Subsequently, telephone interviews or correspondence To establish a comprehensive, factual, annually updated d and cost- was conducted with marketing executives etc. Other sources effective information base on market size, competition patterns, market segments, goals and strategies of the leading players in the market, reviews and forecasts. To assist potential market entrants in evaluating prospective acquisition and joint venture candidates. To complement the organizations internal competitor information gathering efforts with strategic analysis, data interpretation and insight. To suggest for concerned investors in line with the current development of this industry as well as the development tendency. included related magazines, academics, and consulting companies. INFORMATION SOURCES The primary information sources include Company Reports, and National Bureau of Statistics of China etc. To help company to succeed in a competitive market, and Copyright 2012 ResearchInChina understand the size and growth rate of any opportunity.
3 Abstract The human vaccine industry presented the following main characteristics in 2016 in China: 1. Lot release volume of human vaccines declined. Affected by the illegal vaccine case in Mar 2016 in Shandong, the country s lot release volume of human vaccines came to 553.6million doses through the year 2016, down 3.8% over the previous year. The lot release volume of ten vaccines (Hepatitis B vaccine, Diphtheria, Tetanus and acellular Pertussis combined vaccine (adsorbed), rabies vaccine, Japanese encephalitis vaccine, poliomyelitis vaccine, meningococcal vaccine, measles and rubella combined attenuated live vaccine, MMR combined attenuated live vaccine, influenza vaccine, and Hepatitis A Vaccine) was relatively higher, totaling million doses, 84.4% of the country s total, a year-on-year 1.4% drop. 2. The industry was highly concentrated. The Chinese human vaccine market had been highly concentrated, primarily dominated by Beijing Tiantan Biological Products, Chengdu Institute of Biological Products, Shanghai Institute of Biological Products, Lanzhou Institute of Biological Products, Wuhan Institute of Biological Products, and Changchun Institute of Biological Products under China National Biotec Group Company Limited. In 2016, China National Biotec Group accounted for 52.6% of the country s lot release volume of human vaccines, compared with a small fraction of market share for Liaoning Chengda Biotechnology, Changsheng Bio-technology, Shenzhen Kangtai Biological Products, Chongqing Zhifei Biological Products, Beijing Minhai Biotechnology, Walvax Biotechnology, Changchun BCHT Biotechnology, Hualan Biological Engineering, Zhejiang Tianyuan Bio-Pharmaceutical, and Sinovac Biotech. 3. Vaccine enterprises scaled up R&D efforts. Major Chinese vaccine enterprises have intensified their efforts for R&D in order to enhance overall competitiveness in recent years. Walvax Biotechnology has started HPV-2 industrialization project and is expected to launch the product in 2019, and meanwhile has put its 13-valent pneumococcal combined vaccine in phase III clinical trial and is predicted to bring the product to the market in 2018 or Launching of new vaccines will make the company more competitive. Copyright 2012ResearchInChina
4 Copyright 2012ResearchInChina
5 4. Two-child policy, population aging, and new vaccines were drivers of the industry. Along with full implementation of the two-child policy in Oct 2015, the country s newborns increased sharply py to million in 2016 and will remain above 18 million each year over the next five years. Meanwhile, the population aged 60 and over reached million by the end of 2016 and is expected to hit million by In addition, some domestic enterprises have set about developing new vaccines like HPV vaccine and 13-valent pneumococcal vaccine which are expected to be available on the market in 2018 or Pushed by the two-child policy, population aging, and launching of new vaccines, the vaccine industry in China will grow rapidly with an estimated market size of up to RMB31.2 billion in China Human Vaccine Industry Report, highlights the following: Human vaccine industry in China (operating environment, status quo, market demand, market size, circulation channel, import & export, competitive landscape, development trends, etc.); Analysis on Chinese human vaccine market segments(like Hepatitis B Vaccine, Meningococcal Vaccine, Hepatitis A vaccine, Influenza Vaccine, Hib Vaccine, Rabies Vaccine, Varicella Vaccine, Pneumococcal Vaccines, DTP Vaccine, Poliomyelitis Vaccine, Hepatitis E Vaccine), including market demand, lot release volume, competitive landscape, etc.; 19 local vaccine enterprises (operation, gross margin, major customers, R&D and investment, development and forecast, etc.). Copyright 2012ResearchInChina
6 Table of contents 1. Overview of Vaccine Industry 1.1 Definition & Classification 1.2 Industry Chain 2. China Human Vaccine Industry Development Analysis 2.1 Operating Environment International Market Policy Environment Biopharmaceutical Market 2.2 Status Quo 2.3 Supply & Demand 2.4 Market Size 2.5 Circulation Channel 2.6 Import & Export Import Export Average Price 2.7 Competition Pattern 2.8 Development Trend Vaccine for Cervical Cancer Prevention is expected to be launched in China Domestic Pneumococcal 13-valent Conjugate Vaccine is Expected to be launched Two-child Policy Favorable to Industry Development Aging gpopulation p propel p industry development to some extent Industry scale rises stably 3. Human Vaccine Market Segments in China 3.1 Hepatitis B Vaccine 311S Supply &D Demand Lot Release Volume Competition Pattern 3.2 Meningococcal Vaccine Supply & Demand Lot Release Volume Competition Pattern 3.3 Hepatitis A Vaccine Supply & Demand Lot Release Volume Competition Pattern 3.4 Influenza Vaccine Supply & Demand Lot Release Volume 343C Competition Pattern 3.5 Hib Vaccine Supply & Demand Lot Release Volume Competition Pattern Market Forecast 3.6 Human Rabies Vaccine Supply & Demand Lot Release Volume Competition Pattern 3.7 Varicella Vaccine Supply & Demand Lot Release Volume Competition Pattern 38P 3.8 Pneumococcal lvaccines Supply & Demand Lot Release Volume Competition Pattern 3.9 DTP Vaccine Supply & Demand Lot Release Volume Competition Pattern 3.10 Poliomyelitis Vaccine Supply & Demand Lot Release Volume Competition Pattern 3.11 Hepatitis E Vaccine Supply & Demand 3112L Lot trelease Volume Competition Pattern 4. Major Vaccine Manufacturers in China 4.1 China National Biotec Group Profile Beijing Tiantan Biological Products Co., Ltd Chengdu Institute of Biological Products Shanghai Institute of Biological Products Wuhan Institute of Biological Products Lanzhou Institute of Biological Products Changchun Institute of Biological Products
7 Table of contents 4.2 Beijing Tiantan Biological Products Co., Ltd Profile 422O Operation Revenue Structure Gross Margin R&D Cost and Investment Clients Vaccine Business Development and Prospects 4.3 Hualan Biological Engineering Inc Profile 432Operation Revenue Structure R&D Cost and Investment n Clients Vaccine Business 437D Development and dprospects 4.4 Chongqing Zhifei Biological Products Co., Ltd Profile Operation Revenue Structure Gross Margin Major Clients R&D Cost and Investment Development and Prospects 4.5 Walvax Biotechnology Co, Ltd Profile Operation Revenue Structure Gross Margin 455M Major Clients R&D Cost and Investment Vaccine Business Development and Prospects 4.6 Liaoning Cheng Da Co., Ltd Profile Operation Revenue Structure Gross Margin 465Clients R&D Cost and Investment Development and Prospects 4.7 Shenzhen Kangtai Biological Products Co., Ltd Profile 472O Operation Revenue Structure Gross Margin Clients R&D Cost and Investment Development and Prospects 4.8 Changchun Changsheng Life Sciences Limited Profile Operation Revenue Structure R&D Cost and Investment Development and Prospects 4.9 Sinovac Biotech Ltd Profile 492O Operation Revenue Structure Sinovac Biotech (Beijing) 4.10 Changchun BCHT Biotechnology Co. Ltd Profile Operation Development Dynamics 4.11 Zhejiang Tianyuan Bio-Pharmaceutical Co., Ltd Profile Operation 4.12 Dalian Hissen Bio-Pharm Co., Ltd Profile 4.13 NCPC GeneTech Biotechnology Development Profile 4132O Operation 4.14 Dalian Aleph Biomedical Co., Ltd Profile Development Dynamics 4.15 Beijing Minhai Biotechnology Co., Ltd Profile Operation 4.16 Shenzhen Sanofi Pasteur Biological Products 4.17 Other Enterprises Jiangsu SimcereVaxtec Bio-pharmaceutical Xiamen Innovax Biotech CO., LTD Convac Biotechnology Co., Ltd.
8 Classification of Vaccines Vaccine Industry Chain Global Human Vaccine Market Size, Global Human Vaccine Market Size, E Revenue of Top 5 Vaccine Companies, Main Mergers & Acquisitions in the Vaccine Industry Worldwide, Policies in Vaccine Industry, Gross Industrial Output Value of China Biopharmaceutical Industry, Gross Industrial Output Value of China Biopharmaceutical Industry, E EPI Human Vaccine Varieties in China Lot Release Volume of Human Vaccine in China, Top10 Human Vaccines by Lot Release Volume in China, Main Human Vaccine Varieties and Producers Granted Permit for Lot Release in China, 2016 Provinces Completing Online Publicity of Vaccine Procurement in China by the End of Mar 2017 China Human Vaccine Market Size, Import Volume and Value of Human Vaccine in China, China s Human Vaccine Import Volume and Value by Country, 2016 Export Volume and Value of Human Vaccine in China, Top 10 Countries/Regions of China Human Vaccine Export Average Unit Export/Import Price of Human Vaccine in China, Lot Release Volume Breakdown of Human Vaccines in China by Nature of Enterprise, 2016 Lot Release Volume Breakdown of Human Vaccines in China by Nature of Enterprise, 2017H1 Vaccine Lot Release Volume of Major Vaccine Enterprises in China, Lot Release Volume of Vaccines in China by Enterprise, 2016 Vaccine Revenue of Major Human Vaccine Enterprises in China, Selected Charts
9 Market Share of Human Vaccine Industry in China by Enterprise, 2016 R&D Projects and Progress of Major Vaccine Enterprises in China by the End of 2016 Morbidity of Cervical Cancer Worldwide Global HPV Vaccines Global HPV Vaccine Market Size, Shanghai Zerun Biotechnology s Progress in R&D of HPV Vaccine China s Newborns, E Population Aged 60 and Over in China, E Chinese Vaccine Market Size, E Hepatitis B Morbidity and Mortality in China, Lot Release Volume of Hepatitis B Vaccine in China, Lot Release Volume of Hepatitis B Vaccine in China by Dosage Form, Lot Release Volume of Major Hepatitis B Vaccine Companies in China, Share of Major Hepatitis B Vaccine Companies by Lot Release Volume in China, Meningitis Morbidity and Mortality in China, Meningococcal Vaccines Lot Release Volume in China, Meningococcal Vaccines Lot Release Volume in China by Type, Lot Release Volume of Major Meningococcal Vaccines Companies in China, Share of Major Meningococcal Vaccines Companies by Lot Release Volume in China, Hepatitis A Morbidity and Mortality in China, Lot Release Volume of Hepatitis A Vaccine in China, Lot Release Volume of Major Hepatitis A Vaccine Companies in China, Share of Major Hepatitis A Vaccine Companies by Lot Release Volume in China, H7N9 Influenza Morbidity and Mortality in China, Lot Release Volume of Influenza Vaccine in China, Selected Charts
10 Lot Release Volume of Major Influenza Vaccine Companies in China, Share of Major Influenza Vaccine Companies by Lot Release Volume in China, Lot Release Volume of Hib Vaccine in China, Lot Release Volume of Major Hib Vaccine Companies in China, Share of Major Hib Vaccine Companies by Lot Release Volume in China, Rabies Morbidity and Mortality in China, Lot Release Volume of Human Rabies Vaccine in China, Lot Release Volume of Major Human Rabies Vaccine Companies in China, Share of Major Human Rabies Vaccine Companies by Lot Release Volume in China, Lot Release Volume of Varicella Vaccine in China, Lot Release Volume of Major Varicella Vaccine Companies in China, Share of Major Varicella Vaccine Companies by Lot Release Volume in China, Lot Release Volume of Pneumococcal Vaccines in China, Lot Release Volume of Major Pneumococcal Vaccines Companies in China, Share of Major Pneumococcal Vaccine Companies by Lot Release Volume in China, Pertussis Morbidity and Mortality in China, Neonatal Tetanus Morbidity and Mortality in China, Lot Release Volume of DTP Vaccine in China, Lot Release Volume of Major DTP Vaccine Companies in China, Share of Major DTP Vaccine Companies by Lot Release Volume in China, Poliomyelitis Morbidity and Mortality in China, Lot Release Volume of Poliomyelitis Vaccine in China, Lot Release Volume of Major Poliomyelitis Vaccine Companies in China, Share of Major Poliomyelitis Vaccine Companies by Lot Release Volume in China, Hepatitis E Morbidity and Mortality in China, Selected Charts
11 Lot Release Volume of Hepatitis E Vaccine in China, Lot Release Volume of Major Hepatitis E Vaccine Companies in China, Vaccine Varieties of Chengdu Institute of Biological Products Vaccine Lot Release Volume Breakdown of Chengdu Institute of Biological Products by Product, Vaccine Varieties of Shanghai Institute of Biological Products Operation of Shanghai Institute of Biological Products, Vaccine Lot Release Volume Breakdown of Shanghai Institute of Biological Products by Product, Vaccine Lot Release Volume Breakdown of Wuhan Institute of Biological Products by Product, Vaccine Lot Release Volume Breakdown of Lanzhou Institute of Biological Products by Product, Vaccine Lot Release Volume Breakdown of Changchun Institute of Biological Products by Product, Revenue and Net Income of Beijing Tiantan Biological i l Products, Revenue Breakdown of Beijing Tiantan Biological Products by Product, Revenue Structure of Beijing Tiantan Biological Products by Product, Revenue Breakdown of Beijing Tiantan Biological Products by Region, Revenue Structure of Beijing Tiantan Biological Products by Region, Gross Margin of Beijing Tiantan Biological Products by Product, R&D Costs and % of Total Revenue of Beijing Tiantan Biological Products, Main R&D Projects of Beijing Tiantan Biological Products as of the end of 2016 Beijing Tiantan Biological Products Revenue from Top5 Customers and % of Total Revenue, Vaccine Revenue and Percentage of Beijing Tiantan Biological Products, Output & Sales Volume of Major Vaccine Products of Beijing Tiantan Biological Products, 2016 Bidding Status of Beijing Tiantan Biological Products in Centralized Procurement Bidding, 2016 Revenue and Operating Income of Beijing Tiantan Biological Products, E Revenue and Net Income of Hualan Biological Engineering, Revenue Breakdown of Hualan Biological Engineering by Sector, Selected Charts
12 Revenue Structure of Hualan Biological Engineering by Sector, R&D Costs and % of Total Revenue of Hualan Biological Engineering, g, Hualan Biological Engineering s Revenue from Top5 Customers and % of Total Revenue, Output & Sales Volume, Inventory of Hualan Biological Engineering, Vaccine Revenue and Percentage of Hualan Biological Engineering, Major Products and Application of Chongqing Zhifei Biological Products Major Subsidiaries of Chongqing Zhifei Biological Products Revenue and Net Income of Chongqing Zhifei Biological Products, Revenue Breakdown of Chongqing Zhifei Biological Products by Product, Lot Release Volume Breakdown of Chongqing Zhifei Biological Products by Product, R B kd f Ch i Zhif i Bi l i l P d t b R i Revenue Breakdown of Chongqing Zhifei Biological Products by Region, Gross Margin of Chongqing Zhifei Biological Products by Product, Chongqing Zhifei Biological Products Revenue from Top5 Customers and % of Total Revenue, R&D Costs and % of Total Revenue of Chongqing Zhifei Biological Products, Projects under Registration Process of Chongqing Zhifei Biological Products, 2016 Progress of Preclinical Projects of Chongqing Zhifei Biological Products by the end of 2016 Revenue and Operating Income of Chongqing Zhifei Biological Products, E Revenue and Net Income of Walvax Biotechnology, Revenue Breakdown of Walvax Biotechnology by Product, Revenue Breakdown of Walvax Biotechnology by Region, Gross Margin of Walvax Biotechnology by Product, Walvax Biotechnology s Revenue from Top5 Customers and % of Total Revenue, R&D Costs and % of Total Revenue of Walvax Biotechnology, Progress of Products under Registration Declaration of Walvax Biotechnology as of the end of Mar.2017 Output & Sales Volume, Inventory of Walvax Biotechnology, Selected Charts
13 Lot Release Volume of Walvax Biotechnology, Revenue and Operating Income of Walvax Biotechnology, E 2021E Revenue and Net Income of Liaoning Chengda, Revenue Breakdown of Liaoning Chengda by Sector, Revenue Structure of Liaoning Chengda by Sector, Gross Margin of Liaoning Chengda, Liaoning Chengda s Revenue from Top5 Customers and % of Total Revenue, R&D Costs and % of Total Revenue of Liaoning Chengda, Revenue and Net Income of Liaoning Chengda Biotechnology, E Capacity, Output & Sales Volume of Shenzhen Kangtai Biological Products, Revenue and Net Income of Shenzhen Kangtai Biological Products, Revenue Breakdown of Shenzhen Kangtai Biological Products by Product, Lot Release Volume and Percentage of Shenzhen Kangtai Biological Products, Revenue Breakdown of Shenzhen Kangtai Biological Products by Region, Gross Margin of Shenzhen Kangtai Biological Products, Shenzhen Kangtai Biological Products Revenue from Top5 Customers and % of Total Revenue, R&D Costs and % of Total Revenue of Shenzhen Kangtai Biological Products, IPO Fund-Rasing Projects of Shenzhen Kangtai Biological Products Revenue and Net Income of Shenzhen Kangtai Biological Products, E Equity Structure of Changchun Changsheng Life Sciences Revenue and Net Income of Changchun Changsheng Life Sciences, Output & Sales Volume, Inventory of Changchun Changsheng Life Sciences, Revenue Breakdown of Changchun Changsheng Life Sciences by Product, Revenue Structure of Changchun Changsheng Life Sciences by Product, Revenue Breakdown of Changchun Changsheng Life Sciences by Region, Selected Charts
14 Selected Charts Revenue Structure of Changchun Changsheng Life Sciences by Region, R&D Costs and % of Total Revenue of Changchun Changsheng Life Sciences, Progress of Projects under R&D of Changchun Changsheng Life Sciences as of the end of 2016 Revenue and Net Income of Changchun Changsheng Life Sciences, E Revenue and Net Income of Sinovac Biotech, Revenue Breakdown of Sinovac Biotech by Product, Financial Indices of Sinovac Biotech, Financial Indices of Changchun BCHT Biotechnology, Equity Structure of Zhejiang Tianyuan Bio-Pharmaceutical Vaccine Products of Zhejiang Tianyuan Bio-Pharmaceutical Revenue and Net Income of Zhejiang Tianyuan Bio-Pharmaceutical, Financial Indices of Zhejiang Tianyuan Bio-Pharmaceutical, Equity Structure of Dalian Aleph Biomedical Financial Indices of Beijing Minhai Biotechnology, Total Assets and Revenue of Shenzhen Sanofi Pasteur Biological Products, 2016 Development Course of Xiamen Innovax Biotech
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