virology MCQs 2- A virus commonly transmitted by use of contaminated surgical tools & needles produces a disease called serum hepatitis.

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1 virology MCQs 1- A virus which causes AIDS is: a- Small pox virus. b- Coxsackie B virus. c- Mumps virus. d- Rubella virus. e- HIV-III virus. 2- A virus commonly transmitted by use of contaminated surgical tools & needles produces a disease called serum hepatitis. This is: a- Hepatitis A virus. b- Hepatitis B virus. c- Non A non B (hepatitis C) virus. d- Delta agent. e- Yellow fever virus. 3- Chicken pox rashes are: a- Monomorphic in shape. b- Centrifugal in distribution. c- Deeply seated in location. d- Heeled without disfigurement. e- Caused by variola minor. 4- Throat & nasal swabs from a 4 months old infant suffering from acute lower respiratory infection. Their laboratory examination revealed a large enveloped helical virus. The infected cell cultures revealed on staining multinucleate giant cells with cytoplasmic inclusions. The virus is probably: a- Rhinovirus. b- Corona virus. c- Adenovirus. d- Parainfluenza virus. e- Respiratory syncitial virus. 5- All picorna viruses are: a- Human pathogens. b- Immunologically cross acting.

2 c- Not enveloped. d- Not inactivated by gastric fluid. 6- A febrile viral disease characterized by infection & swelling of the parotid salivary glands is produced by a large enveloped helical virus which produce hemadsorption of erythrocytes to infected cells. This virus is: a- Cytomegalovirus. b- Coxsackie virus. c- E.B virus. d- Mumps virus. e- ECHO virus. 7- A virus which is commonly associated with a mild disease called hand, foot & mouth disease which appears in epidemic of families is: a- Herpes simplex I. b- Foot & mouth disease virus. c- Coxsackie A16. d- Varicella-zoster. e- Rubella virus. 8- The antiviral effect produced by interferon is associated with inhibition of: a- Virus adsorption on the cell. b- Penetration of the virus into the cell. c- Replication of the virul nucleic acid. d- Translation of the viral mrna to proteins. e- Release of the virus from the cell. 9- Viral replivation: a- Occurs by binary fission. b- Requires host cell macromolecules. c- Occurs within the host cell lysosomes. d- Can be prevented by antibiotics. e- Can occur in synthetic media. 10- A helpful test in diagnosis of infectious mononucleosis is the: a- Paul-Bunnell. b- Weil-felix. c- Widal. d- Wasserman. e- Blood culture.

3 11- A 7 years old boy suffering from sore mouth, excessive salivation & fever. On examination of the mouth, vesicles were observed & the gingivae were reddish & swollen. The laboratory examination of the vesicular fluid revealed a large icosahedral enveloped virus, by electron microscopy small pock lesion in the chorioallantoic membrane of chicken eggs, & in cell cultures the CPE was in the form of microplaques. The virus is probably: a- Coxsackie A virus. b- Coxsackie B virus. c- ECHO virus. d- E.B virus. e- Herpes simplex virus. 12- In tropical Africa most malignant tumors occurring in children are represented by: a- Burkitt's lymphoma. b- Hodgkin's disease. c- Kaposi sarcoma. d- Neurofibromatoma. 13- Dene particle can be isolated from: a- Yellow fever. b- Hepatitis A infection. c- Hepatitis B infection. d- Non A, Non B hepatitis. 14- Dendritic corneal ulcer can be treated with: a- Thiosemicarbitone. b- Adamantanamide. c- Adenine arabinoside (Ara-A). d- Penicillin. 15- Paul-Bunnell test is used in diagnosis of the following viral infection a- Cytomegalovirus. b- Epstein-barr virus. c- Hepatitis A virus. d- Hepatitis B virus.

4 16- Virus which contains the enzyme reverse transcriptase: a- Influenza virus. b- Small pox virus. c- Rota virus. d- Human immunodeficiency virus. e- Respiratory syncitial virus. 17- A virus which contains a hemagglutinin & a neuraminidase is: a- Rubella virus. b- Adenovirus. c- Reo virus. d- Influenza virus. e- Respiratory syncitial virus. 18- Hepatitis A virus (HAV) is usually transmitted by: a- Respiratory secretions. b- Contact with blood. c- Sexual contact. d- Fecal-oral route. e- Mosquitoes. 19- The protein core which surrounds the nucleic acid of animal viruses is called: a- Envelope. b- Nucleocapsid. c- Capsomer. d- Capsid. e- Heson. 20- Latency is an outcome particularly characteristic of which of the following viruses: a- Polio viruses. b- Rhino viruses. c- Herpes viruses. d- Influenza viruses. e- ECHO viruses. 21- Dene particles: a- Are found in hepatitis A virus infection. b- Are found in hepatitis B virus infection. c- Are found in hepatitis non A, non B virus infection. d- Are found cultivated on tissue culture.

5 e- Are found cultivated in chick embryo. 22- In all DNA containing viruses. DNA is synthesized in the nucleus EXCEPT for: a- Herpes viruses. b- Adenoviruses. c- Pox viruses. d- Papovaviruses. e- Parvoviruses. 23- Positive Paul-Bunnell test is the diagnosis of one of the following: a- Varicella-zoster virus. b- Cytomegalovirus. c- E.B virus. d- Measles virus. e- Rubella virus. 24- Acyclovir is relatively safe & effective in the treatment of: a- Respiratory syncitial viral infection. b- AIDS. c- Herpes encephalitis. d- Influenza. e- Hepatitis B infection. 25- All the following statements are true for rabies EXCEPT: a- It has short incubation period. b- It can be diagnosed by Negri bodies. c- It can be treated by successful vaccine. d- It is also known as hydrophobia. e- Patients have excessive salivation. 26- The following statements are true for heres simplex virus EXCEPT: a- It is an enveloped virus. b- It can produce genital lesions. c- It can produce fatal encephalitis. d- It produces intracytoplasmic inclusion bodies. e- It is associated with cervical cancer. 27- One of the following statements is NOT true for viruses: a- Viruses contain either DNA or RNA. b- Viruses lack mitochondria. c- Viruses contain a protein coat.

6 d- Viruses multiply by binary fission. e- Viruses require specific receptors to infect cells. 28- One of the following viruses is transmitted by mosquitoes: a- Rubella virus. b- Rabies virus. c- Polyomyelitis virus. d- Yellow fever virus. e- Measles virus. 29- One of the following viruses produce eosinophilic intracytoplasmic inclusion bodies called Negri bodies: a- Herpes simplex virus. b- Small pox virus. c- Adenovirus. d- Cytomegalovirus. e- Rabies virus. 30- The following viruses spread by fecal-oral route EXCEPT: a- Polioviruses. b- ECHo viruses. c- Hepatitis A viruses. d- Narwalk agent. e- Corona virus. 31- All the following viruses produce rash EXCEPT: a- Small pox virus. b- Vericella-zoster virus. c- Coxsackie virus. d- ECHO virus. e- Rota virus. 32- All the following viruses are secreted in the saliva EXCEPT: a- Hepatitis A virus. v- Hepatitis B virus. c- HIV virus. d- Mumps virus. e- Cytomegalovirus. 33- A virus which produces pocks in the chorioallantoic membrane of embryonated

7 chicken eggs is: a- Adenovirus. b- Influenza virus. c- Mumps virus. d- Herpes simplex virus. e- Rabies virus. 34- Interferon prevents infection with viruses by: a- Blocking their adsorption to cells. b- Blocking their penetration to cells. c- Inhibiting their intracellular multiplication. d- Cleaving their nucleic acid. 35- The genetic character of the virus is carried on the: a- Core. b- Capsid. c- Envelope. d- Non metabolic enzymes. 36- Supercoiled DNA: a- A property of the brick-shaped big pox virus. b- A character of papova viruses. c- The linear molecule of ds DNA. d- The linear molecule of ss DNA. 37- The following agents are considered as the cause of sexually transmitted diseases EXCEPT: a- Condyloma acuminatum. b- Coliform. c- Hepatitis B virus. d- Ureaplasma. 38- Clinical syndrome caused by ECHO viruses include the following EXCEPT: a- Respiratory tract infection. b- Diarrhea. c- Skin rash. d- Congenital fetal defects. 39- Which of the following viruses does NOT contain DNA:

8 a- Cytomegalovirus. b- Varicella-zoster virus. c- Respiratory syncitial virus. d- Variola virus. 21- B 1- E 22- C 2- B 23- C C 4- D 25- A 5- C 26- D 6- D 27- D 7- C 28- D 8- D 29- E 9- B 30- E 10- A 31- E 11- E 32- A 12- A 33- D 13- D 34- C 14- A 35- A 15- B 36- B 16- D 37- B 17- D D D 20- C