Clinical and biochemical characteristics of suspected dengue fever in an ambulatory care family medical clinic, Aga Khan University, Karachi, Pakistan
|
|
- Wesley Ford
- 6 years ago
- Views:
Transcription
1 Clinical and biochemical characteristics of suspected dengue fever in an ambulatory care family medical clinic, Aga Khan University, Karachi, Pakistan Firdous Jahan, # Kashmira Nanji, Waris Qidwai, Rozina Roshan & Hira Waseem Department of Family Medicine (FAMCO), Oman Medical College-Sohar, PO Box 391, PC 321, Al-Tareef, Sohar, Sultanate Oman. Abstract A medical chart review was carried out in an ambulatory family medical clinic attached to the Aga Khan University Hospital, Karachi, Pakistan. The study revealed that all febrile patients the mean fever spike was 39.8 C. The common symptoms were bodyache (46%), nausea (12%) and headache (10%). Other clinical findings were eye pain, backache and anorexia. Out of thirteen patients who had dengue IgM done, nine showed positive results. In laboratory examination, thrombocytopenia was found in 53.4% of patients. Low haemoglobin was found in 51% and leucopenia in 32.9% of patients. Keywords: Dengue fever; Ambulatory care; Medical chart review; Clinical and biochemical changes; Suspected DF; Aga Khan University Hospital; Karachi, Pakistan. Introduction Dengue is a widespread mosquito-borne infection in human beings which, in recent years, has become a major public health concern worldwide. [1] Dengue is re-emerging throughout the tropical world, causing frequent recurrent epidemics. [2,3] In Pakistan, the first major outbreak was recorded in 1994 in Karachi. Since then, Karachi has experienced recurrent outbreaks during 2005, 2006 and Other cities in Pakistan which recorded major dengue outbreaks were Lahore (2008) and Islamabad (2010). Three serotypes, viz. DENV-1, DENV-2 and DENV-3 (subtype III), have been found circulating in the country. [4] During 2010, the Dengue Surveillance Cell of the Sind Province of Pakistan reported 563 serologically-confirmed cases at the Aga Khan University Hospital in Karachi. The reported cases were usually complicated or were with haemorrhagic manifestations. However, at an # firdous@omc.edu.om Dengue Bulletin Volume 35,
2 ambulatory care family medical clinic (primary health care centre) attached to the Aga Khan University Hospital, the usual presentation was mild-to-moderate fever, treated as suspected dengue. The present study highlights the clinical and biochemical characteristics of suspected cases as observed at an ambulatory care family medical clinic (ACFMC). Materials and methods The primary investigator of this study trained the person who did the chart review and data collection in the clinic. Data were collected through a structured instrument which was developed after brainstorming sessions with the authors. Demographic information, gender and age were recorded for all patients. Clinical presentation (fever), minimum and maximum rise of temperature, nausea and/or vomiting, rash, abdominal pain, myalgia, headache and haemorrhage were recorded. Results of biochemical tests, which were carried out depending on clinical findings, were recorded. Thrombocytopenia was defined as a platelet count, cells/mm 3 blood. A haematocrit value rising by 20% was considered as high. Similarly, leucopenia was defined as a white cell count <5000 cells/mm 3, neutropenia as neutrophils <40%, and lymphocytosis as lymphocytes >45%. Alanine aminotransferase (ALT) was considered as raised if it was 55 and 33 IU/L for males and females respectively. Aspartate aminotransferase (AST) was defined as raised if it was 46 and 32 IU/L for males and females respectively. The Statistical Package for Social Sciences (SPSS) version 15.0 was used for data entry and statistical analysis. Descriptive statistics were calculated. Median (± inter-quartile ranges) were reported for continuous variables such as age, gender, etc. Numbers and percentages were reported for all other categorical variables such as clinical characteristics (fever, headache, bodyache, etc.) and biochemical tests (thrombocytopenia, leucopenia, etc.) Most developing countries have epidemics of febrile illnesses which can be confused with dengue fever; therefore, other investigations such as blood culture, urine culture, malaria immunochromatography (ICT), typhidot IgM, etc., were done according to clinical symptoms and signs. Results The total number of patients who presented with fever in the community health centre (outpatient clinic) during October-November was 125, of whom 78 (62.4%) were male while 47 (37.6%) were female. 60 Dengue Bulletin Volume 35, 2011
3 The mean fever spike was 39.8 C. The common symptoms were bodyache (46%), nausea (12%) and headache (10%). Other clinical findings were eye pain, backache and anorexia (Table 1). Table 1: Clinical features of patients with suspected DF at an ambulatory care family medical clinic, Karachi, Pakistan Characteristics n % Age* 32 (±15) Gender Male Female Bodyache/headache Eye pain Backache Nausea/Anorexia *Mean age. In laboratory investigations, thrombocytopenia was found in 50 out of 92 (54.3%) patients. Low haemoglobin was found in 44 out of 86 (51%) patients, high haemoglobin and haematocrit level was found in 42 out of 86 (48%) patients, leucopenia in 29 out of 89 (32.9%), neutropenia in 9 out of 70 (13%), lymphocytosis 10 out of 69 (14.5%), lymphopenia 26 out of 69 (37.6%), raised ALT 17 out of 41 (41%) and raised AST 25 out of 29 (86%) patients. Raised ALT/AST was found in 5% of the cases (Table 2). Dengue IgM was done in 13 patients and 9 were positive (69.2%). Other investigations done according to clinical presentation revealed significant positive blood culture for Salmonella Typhi and serum Typhidot-IgM. Severe thrombocytopenia < was found in 9 (7%) cases, high haematocrit >20 was found in 84 (67%) cases and severe leucopenia <3.0 was found in 12 (10%) cases. Based on these criteria, 52 patients were referred to the Emergency and 9 were hospitalized for platelet transfusion; the rest were sent home after intravenous rehydration and were asked to return for a close follow-up in the ACFMC clinic. Dengue Bulletin Volume 35,
4 Table 2: Laboratory findings of the study participants with suspected DF (n=125) Tests n=tests ordered Test positive % Thrombocytopenia Low haemoglobin High haemoglobin Haematocrit level 70 40±5.8 Lymphocytosis Leucopenia Neutropenia Raised AST Raised ALT Discussion The results of this study describe the demographic trends of suspected dengue infections in ambulatory care. As described in available literature, the clinical presentation is somehow classical in most of the suspected DF cases. [5] Dengue virus is now endemic in Pakistan, circulating throughout the year, with a peak incidence in the post-monsoon period. The mean age detected is 32 years (3-78). The median age of dengue patients has decreased and younger patients seem to have become more susceptible. [6] Clinical presentation in nearly half of the patients was severe bodyache followed by backache, nausea and headache as reported by others. [7] In those who had the diagnosis of suspected DF, the most common biochemical changes were thrombocytopenia and raised AST. Nearly half of the patients had high haemoglobin and haematocrit levels. Dengue IgM was positive in 9 out of 13 patients on whom the test was done. Among patients of DF in other parts of Pakistan, tests revealed similar clinical characteristics, with some variations in symptomatology. [8,9]. Clinical characteristics and biochemical changes, though variable in different parts of the world, show some similarities like thrombocytopenia, high haematocrit, leucopenia, lymhocytosis and lymphonia, that were found in this audit as well. [5,10,11,12] Both ALT and AST levels were high in the biochemical profile but the level of AST was significantly high. [13] Total and differential leukocyte count may be useful for the identification of patients at risk of haemorrhage and their utility needs should be studied further. 62 Dengue Bulletin Volume 35, 2011
5 Other diagnosis in ambulatory care was enteric fever in 34 out of 53 (62%) patients. Although malaria is highly prevalent in this part of the country, but in post-monsoon fever cases, out of 59 tests done, only one malaria ICT was found positive. A significant number of patients were referred to the Emergency room for hospitalization, but most of them were discharged after intravenous rehydration while 9 out of 52 patients needed platelet transfusion. In this study no one had overt bleeding or minor haemorrhage but cases of impending haemorrhage with severe thrombocytopenia were immediately referred for platelet transfusion. Primary care physicians have an active role to play in providing care and support and identifying the signs of impending haemorrhage which has serious consequences. Dengue fever cases need referral to tertiary care for intravenous fluid replacement and platelet transfusion along with supportive care. Acknowledgements The authors gratefully acknowledge the help of Sumiara Ihtesham (Head Nurse, CHC Clinic) and Dr Samina Hossien (Assistant Physician In-charge, CHC Clinic). References [1] World Health Organization. Dengue and dengue haemorrhagic fever. Fact sheet no.117 March Geneva: WHO, accessed 11 January [2] Guzman MG, Kouri G. Dengue: an update Lancet Infect Dis. 2002; 2: [3] [4] [5] [6] [7] [8] [9] Thomas SJ, Strickman D, Vaughn DW. Dengue epidemiology: virus epidemiology, ecology, and emergence. Adv Virus Res. 2003; 61: Raheel U, Faheem M, Riaz MN, Kanwal N, Javed F, Zaidi NS, Qadri I. Dengue fever in the Indian subcontinent: an overview. J Infect Dev Ctries. 2011; 26; 5(4): Ageep AK, Malik AA, Elkarsani MS. Clinical presentations and laboratory findings in suspected cases of dengue virus. Saudi Med J Nov; 27(11): Syed M, Saleem T, Syeda UR, Habib M, Zahid R, Bashir A, Rabbani M, Khalid M, Iqbal A, Rao EZ, Shujja-ur-Rehman, Saleem S. Knowledge, attitudes and practices regarding dengue fever among adults of high and low socioeconomic groups. J Pak Med Assoc Mar; 60(3): Muhammad A, Adel MK, Eman HL, Shahid B, Adnaan YA, Sawsan AU. Characteristics of Dengue Fever in a large public hospital, Jeddah, Saudi Arabia. J Ayub Med Coll Abottabad Jun; 18(2): Riaz MM, Mumtaz K, Khan MS, Patel J, Tariq M, Hilal H, Siddiqui SA, Shezad F. Outbreak of dengue fever in Karachi 2006: a clinical perspective. J Pak Med Assoc. Jun 2009; 59(6): Khan E, Siddiqui J, Shakoor S, Mehraj V, Jamil B. Dengue outbreak in Karachi, Pakistan, 2006: experience at a tertiary care center. Trans R Soc Trop Med Hyg. 2007; 101: Dengue Bulletin Volume 35,
6 [10] Keating J. An investigation into the cyclical incidence of dengue fever. Soc Sci Med. 2001; 53: [11] Gupta E, Dar L, Kapoor G, Broor S. The changing epidemiology of dengue in Delhi, India. Virol J. 2006; 3: 92. [12] Chuang VW, Wong TY, Leung YH, Ma ES, Law YL. Review of dengue fever cases in Hong Kong during 1998 to Hong Kong Med J. 2008; 14: Sumarmo. Dengue haemorrhagic fever in Indonesia. [13] Southeast Asian J Trop Med Public Health. 1987; 18: Dengue Bulletin Volume 35, 2011
Dengue NS1 Antigen - for Early Detection of Dengue Virus Infection
ORIGINAL ARTICLE Dengue NS1 Antigen - for Early Detection of Dengue Virus Infection Amol Hartalkar 1, Sheetal Hartalkar 2, Makarand Wani 3, Arvind Yadav 4 Associate Professor 1, Assistant Professor 2,
More informationClinicopathological profile of dengue like illness in children A prospective study
ISSN: 2319-7706 Volume 3 Number 2 (201) pp. 596-600 http://www.ijcmas.com Original Research Article Clinicopathological profile of dengue like illness in children A prospective study M.Abhishek 1*, M Gayathri
More informationClinical Profile of the Dengue Infection in Children
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-issn: 2279-0853, p-issn: 2279-0861.Volume 17, Issue 3 Ver.7 March. (18), PP 01-05 www.iosrjournals.org Clinical Profile of the Dengue Infection
More informationA study of clinical profile of dengue fever in a tertiary care hospital of Jamnagar, Gujarat, India
International Journal of Research in Medical Sciences Chhotala YH et al. Int J Res Med Sci. 2016 Oct;4(10):4500-4504 www.msjonline.org pissn 2320-6071 eissn 2320-6012 Research Article DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20163318
More informationSeroprevalence and Recent Trends of Dengue in a Rural Area in South India
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 1 (2017) pp. 36-41 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2017.601.005
More informationCrimean-Congo hemorrhagic fever in a dengue-endemic region: lessons for the future
Case Report Crimean-Congo hemorrhagic fever in a dengue-endemic region: lessons for the future Farheen Ali 1, Taimur Saleem 2, Umair Khalid 2, Syed Faisal Mehmood 1, Bushra Jamil 3 1 Department of Medicine,
More informationORIGINAL ARTICLE. SEROPREVALENCE OF DENGUE IN TERTIARY CARE CENTRE AT LUCKNOW Shipra Singhal 1, Krati R. Varshney 2, Vineeta Mittal 3, Y. I. Singh 4.
SEROPREVALENCE OF DENGUE IN TERTIARY CARE CENTRE AT LUCKNOW Shipra Singhal 1, Krati R. Varshney 2, Vineeta Mittal 3, Y. I. Singh 4. 1. Junior Resident, Department of Microbiology, Era s Lucknow Medical
More informationA study of NS1 antigen and platelet count for early diagnosis of dengue infection
ISSN: 2319-7706 Volume 2 Number 12 (2013) pp. 40-44 http://www.ijcmas.com Original Research Article A study of NS1 antigen and platelet count for early diagnosis of dengue infection Santosh Shivajirao
More informationORIGINAL ARTICLE. A STUDY ON CLINICAL, LABORATORY PROFILE AND OUTCOME OF DENGUE FEVER Vanamali D.R 1, L. Venugopal 2, P. Yeshwanth 3, Dilip Rampure 4
A STUDY ON CLINICAL, LABORATORY PROFILE AND OUTCOME OF DENGUE FEVER Vanamali D.R 1, L. Venugopal 2, P. Yeshwanth 3, Dilip Rampure 4 HOW TO CITE THIS ARTICLE: Vanamali D.R, L. Venugopal, P. Yeshwanth, DilipRampure.
More informationOriginal Article DENGUE FEVER OUTBREAK 2011: CLINICAL PROFILE OF CHILDREN PRESENTING AT MADINA TEACHING HOSPITAL FAISALABAD
Original Article DENGUE FEVER OUTBREAK 11: CLINICAL PROFILE OF CHILDREN PRESENTING AT MADINA TEACHING HOSPITAL FAISALABAD Aisha Sajid 1, Asim Ikram 2, Mubashir Ahmed 3 1 Assistant Professor, Pediatrics
More informationInternational Journal of Health Sciences and Research ISSN:
International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571 Original Research Article A Comparative Study of Primary & Secondary Dengue in a Tertiary Care Centre Sheeba P.M 1, Arun
More informationfor determining dengue severity in Thai patients
Comparison of the 1997 and 2009 WHO classifications for determining dengue severity in Thai patients Auchara Tangsathapornpong 1, Pornumpa Bunjoungmanee 1, Pimpare Pengpris 1 and Thana Khawcharoenporn
More informationClinical and Laboratory Abnormalities due to Dengue in Hospitalized Children in Mumbai in 2004
Clinical and Laboratory Abnormalities due to Dengue in Hospitalized Children in Mumbai in 2004 Ira Shah! and Bhushan Katira Department of Paediatrics, B.J. Wadia Hospital for Children, Parel, Mumbai 400
More informationFrequency of Dengue virus Infection among Febrile Patients of Lahore
Global Journal of Health Science; Vol. 9, No. 10; 2017 ISSN 1916-9736 E-ISSN 1916-9744 Published by Canadian Center of Science and Education Frequency of Dengue virus Infection among Febrile Patients of
More informationAn Experience with Dengue in Pakistan: An Expanding Problem
Ibnosina J Med BS 3 ARTICLE An Experience with Dengue in Pakistan: An Expanding Problem Shazia T. Hakim 1,4, Syed M. Tayyab 1, Shams U. Qasmi 3, Sayyada G. Nadeem 2 1. Virology & Tissue Culture Laboratory,
More informationA Study of Clinical Profile of Dengue Fever in Kollam, Kerala, India
A Study of Clinical Profile of Dengue Fever in Kollam, Kerala, India Rachel Daniel*!, Rajamohanan** and Aby Zachariah Philip*** *Bishop Benziger Hospital, Kollam, Kerala, India **Sree Avittom Thirunal
More informationEpidemics of dengue virus in the recent outbreak in 2017, in District Mardan, Khyber-Pakhtunkhwa province of Pakistan
International Journal of Biosciences IJB ISSN: 2220-6655 (Print) 2222-5234 (Online) http://www.innspub.net Vol. 12, No. 3, p. 280-284, 2018 RESEARCH PAPER OPEN ACCESS Epidemics of dengue virus in the recent
More informationFrequency of worsening liver function in severe dengue hepatitis patients receiving paracetamol: A retrospective analysis of hospital data
400 ORIGINAL ARTICLE Frequency of worsening liver function in severe dengue hepatitis patients receiving paracetamol: A retrospective analysis of hospital data Ahsan Ali Syed, Faisal Aslam, Haris Hakeem,
More informationof Physiology, Khyber Girls Medical College, Peshawar
Original Article Clinical Spectrum of Dengue Fever: A Single Center Study Shahzad Ahmad*, Mohammad Sajjad Ali Khan*, Muhammad Zaheer ullah Babar*, Iftikhar Ali Shah* and Afsheen Mahmood** * Department
More informationHaematological profile of dengue fever
International Journal of Research in Medical Sciences Tahlan A et al. Int J Res Med Sci. 2017 Dec;5(12):5367-5371 www.msjonline.org pissn 2320-6071 eissn 2320-6012 Original Research Article DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20175456
More informationKnowledge, Attitude and Practice Regarding Dengue Infection among Ipoh Community, Malaysia
Journal of Applied Pharmaceutical Science Vol. 7 (08), pp. 099-103, August, 2017 Available online at http://www.japsonline.com DOI: 10.7324/JAPS.2017.70814 ISSN 2231-3354 Knowledge, Attitude and Practice
More informationA three year retrospective study on the increasing trend in seroprevalence of dengue infection from southern Odisha, India
Indian J Med Res 140, November 2014, pp 660-664 A three year retrospective study on the increasing trend in seroprevalence of dengue infection from southern Odisha, India Sanghamitra Padhi, Muktikesh Dash,
More informationNEUROLOGICAL MANIFESTATIONS IN DENGUE PATIENTS
NEUROLOGICAL MANIFESTATIONS IN DENGUE PATIENTS Chitsanu Pancharoen and Usa Thisyakorn Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Abstract. To determine the
More informationSynopsis of Findings from Recent Studies on Dengue in Sri Lanka
Synopsis of Findings from Recent Studies on Dengue in Sri Lanka S.A.M. Kularatne a*, S.L. Seneviratne b*, G.N. Malavige c*, S. Fernando c, V.G.N.S. Velathanthiri c, P.K. Ranatunga d, E.S. Wijewickrama
More informationPatterns of Gall Bladder Wall Thickening in Dengue Fever: A Mirror of the Severity of Disease
Original Article Patterns of Gall Bladder Wall Thickening in Dengue Fever: A Mirror of the Severity of Disease Abstract Authors Jitendra Premjibhai Parmar 1, Chander Mohan 2, Maulik Vora 3 Affiliations
More informationUsa Thisyakorn and Chule Thisyakorn
CHILDHOOD DENGUE DISEASES: A TWENTY YEARS PROSPECTIVE STUDY Usa Thisyakorn and Chule Thisyakorn Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Abstract. Dengue
More informationHAEMATOLOGICAL CHANGES IN DENGUE FEVER
ORIGINAL ARTICLE HAEMATOLOGICAL CHANGES IN DENGUE FEVER 1 2 3 4 5 Shaista Choudhary,B.R Shivkumar, Adisesha Shankar, Y.A. Manjunatha, M.M. Priyadarshini ABSTRACT Dengue infection has been known in India
More informationClinicohaematological profile of dengue in children: a hospital based study
International Journal of Contemporary Pediatrics Majeed IA et al. Int J Contemp Pediatr. 2017 Jul;4(4):1340-1344 http://www.ijpediatrics.com pissn 2349-3283 eissn 2349-3291 Original Research Article DOI:
More informationHaemogram profile of dengue fever in adults during 19 September 12 November 2008: A study of 40 cases from Delhi
Haemogram profile of dengue fever in adults during 19 September 12 November 2008: A study of 40 cases from Delhi Sonia Advani, # Shikha Agarwal & Jitender Verma Department of Biotechnology Engineering,
More informationDIFFERENCES IN CLINICAL FEATURES BETWEEN CHILDREN AND ADULTS WITH DENGUE HEMORRHAGIC FEVER/DENGUE SHOCK SYNDROME
Southeast Asian J Trop Med Public Health DIFFERENCES IN CLINICAL FEATURES BETWEEN CHILDREN AND ADULTS WITH DENGUE HEMORRHAGIC FEVER/DENGUE SHOCK SYNDROME Vannyda Namvongsa 1, 2, Chukiat Sirivichayakul
More informationA Study of Clinical Spectrum of Dengue Fever in A Tertiary Care
A Study of Clinical Spectrum of Dengue Fever in A Tertiary Care Centre. Dr. Gargi Pathak 1, Dr. Anuya Chauhan 2, Dr. Malvika Nagpure 3*, Dr. Kinjal Katheriya 4 1 Professor and Head of Unit, 2 Assistant
More informationA study of clinical profile of patients with Dengue fever at a tertiary care hospital
International Journal of Advances in Medicine Sreenivasulu T et al. Int J Adv Med. 2018 Feb;5(1):202-206 http://www.ijmedicine.com pissn 2349-3925 eissn 2349-3933 Original Research Article DOI: http://dx.doi.org/10.18203/2349-3933.ijam20180085
More informationThe differences of clinical manifestations and laboratory findings in children and adults with dengue virus infection
Journal of Clinical Virology 39 (2007) 76 81 The differences of clinical manifestations and laboratory findings in children and adults with dengue virus infection Leera Kittigul a,, Piyamard Pitakarnjanakul
More informationDengue Symptoms Significance in Anti-Dengue Drug Development: Road Less Travelled
www.bioinformation.net Volume 13(5) Hypothesis Dengue Symptoms Significance in Anti-Dengue Drug Development: Road Less Travelled Anubrata Paul*, Arpana Vibhuti SRM University, Delhi-NCR, Sonepat, Haryana,
More informationJMSCR Vol 05 Issue 02 Page February 2017
www.jmscr.igmpublication.org Impact Factor 5.84 Index Copernicus Value: 83.27 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi.org/10.18535/jmscr/v5i2.146 Original Article A study of Clinico-Haematological
More informationReport of Four Volunteers with Primary, Secondary and Tertiary Dengue Infections during a Prospective Cohort Study
Report of Four Volunteers with Primary, Secondary and Tertiary Dengue Infections during a Prospective Cohort Study Herman Kosasih a, Hadi Yusuf b, Primal Sudjana b, Bachti Alisjahbana b, Suharyono Wuryadi
More informationPredictors of Severity of Dengue Fever in Tertiary Care Hospitals
ABSTRACT BACKGROUND: Dengue fever, an emerging public health issue in Pakistan bears considerable morbidity and mortality. This descriptive cross sectional study was conducted to analyze clinical, hematological
More informationInternational Journal of Pharma and Bio Sciences A STUDY OF CLINCAL PROFILE IN DENGUE CASES ABSTRACT
Research Article Microbiology International Journal of Pharma and Bio Sciences ISSN 0975-6299 A STUDY OF CLINCAL PROFILE IN DENGUE CASES DHANDAPANI E.* 1 AND SUDHA M 2 1 Formerly Professor of Medicine,
More informationSero-Prevalence of Dengue Infection by Rapid Immunochromatographic Assay from Tertiary Care Medical College Hospital in Coimbatore, India
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 12 (2016) pp. 106-111 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2016.512.012
More informationA Study of platelet count with respect to Severity in the patients of Dengue at tertiary health care centre
Original article: A Study of platelet count with respect to Severity in the patients of Dengue at tertiary health care centre Satish D.Ashtekar 1, *Mahesh V.Kamale 2 1Associate Professor, Department of
More informationStudy on the effectiveness of transfusion program in dengue patients receiving platelet transfusion
Kulkarni et al. 1 1 ORIGINAL ARTICLE OPEN ACCESS Study on the effectiveness of transfusion program in dengue patients receiving platelet transfusion Nagarekha Kulkarni ABSTRACT Aims: Dengue infection is
More informationThe 2011 Dengue Haemorrhagic Fever Outbreak in Lahore - An Account of Clinical Parameters and Pattern of Haemorrhagic Complications
ORIGINAL ARTICLE The 2011 Dengue Haemorrhagic Fever Outbreak in Lahore - An Account of Clinical Parameters and Pattern of Haemorrhagic Complications Shahid Ahmed, Wasim Wali Mohammad, Faran Hamid, Amim
More informationOriginal Research Article. E. Chandra Shekar 1, Laxminarayana 2, B. Kishan 3 *, Suresh Kumar 1, Bikshapati Rao 1
International Journal of Advances in Medicine Shekar EC et al. Int J Adv Med. 2017 Feb;4(1):218-224 http://www.ijmedicine.com pissn 2349-3925 eissn 2349-3933 Original Research Article DOI: http://dx.doi.org/10.18203/2349-3933.ijam20170115
More informationCategorisation of Dengue based on duration of fever and serological markers in a tertiary care hospital
Indian Journal of Basic and Applied Medical Research; June 27: Vol.-6, Issue- 3, P. 49-43 Original Article Categorisation of Dengue based on duration of fever and serological markers in a tertiary care
More informationObservation on dengue cases from a virus diagnostic laboratory of a tertiary care hospital in north India
Indian J Med Res 142 (Supplement), December 2015, pp 7-11 DOI:10.4103/0971-5916.176596 Observation on dengue cases from a virus diagnostic laboratory of a tertiary care hospital in north India Om Prakash,
More informationSri Lankan Journal of Infectious Diseases 2014 Vol.4(2): DOI:
99 Research article A preliminary study on clinical profiles of dengue and dengue haemorrhagic fever suspected patients from two hospitals in the Western Province of Sri Lanka PDNN Sirisena 1, F Noordeen
More informationClinical and Serological Study of First Large Epidemic of Dengue in and around Lucknow, India, in 2003
Clinical and Serological Study of First Large Epidemic of Dengue in and around Lucknow, India, in 2003 Janak Kishore, Jagdeep Singh, T.N. Dhole and A. Ayyagari Department of Microbiology, Sanjay Gandhi
More informationResearch Article Clinical Profile of Dengue Fever in Children: A Study from Southern Odisha, India
Scientifica Volume 2016, Article ID 6391594, 6 pages http://dx.doi.org/10.1155/2016/6391594 Research Article Clinical Profile of Dengue Fever in Children: A Study from Southern Odisha, India Shubhankar
More informationPatterns and Trends in Atypical Manifestations of Dengue among Inpatient Adults in Tertiary Care Teaching Institute of South India
ORIGINAL RESEARCH www.ijcmr.com Patterns and Trends in Atypical Manifestations of Dengue among Inpatient Adults in Tertiary Care Teaching Institute of South India Nagarajan Natarajan 1, Sindhu Cugati 2,
More informationLiver Functions as a marker of severity of disease in children with Dengue fever
Article ID: WMC004962 ISSN 2046-1690 Liver Functions as a marker of severity of disease in children with Dengue fever Peer review status: No Corresponding Author: Dr. Sampada A Tambolkar, Associate Professor,
More informationSharing of HA Current Protocols on Dengue Fever (DF) Ms MY KONG, SNO, HA CICO office 31 August 2018
Sharing of HA Current Protocols on Dengue Fever (DF) Ms MY KONG, SNO, HA CICO office 31 August 2018 1 HA Preparedness for Dengue Fever Outbreak HA Operational Plan for Dengue Fever Outbreak http://ha.home/ho/cico/ha_operational_plan_dengue.pdf
More informationPRESENCE OF BOTH DENGUE SPECIFIC NS1 ANTIGEN AND IMMUNOGLOBULIN M ANTIBODY IN CONFIRMED DENGUE PATIENTS IN KOLKATA
RIGINAL REPRT JUMMEC 2018:21(2) PRESENCE F BTH DENGUE SPECIFIC NS1 ANTIGEN A IMMUNGLBULIN M ANTIBDY IN CNFIRMED DENGUE PATIENTS IN KLKATA Poddar S 1, Mukim Y 2, Pal D 3, Bhattacharya N 4 and Hati AK 1
More informationRECENT TREND OF SEROPREVALENCE OF DENGUE IN HARYANA
Int. J. Pharm. Med. & Bio. Sc. 2013 Seema Mittal et al., 2013 Research Paper ISSN 2278 5221 www.ijpmbs.com Vol. 2, No. 4, October 2013 2013 IJPMBS. All Rights Reserved RECENT TREND OF SEROPREVALENCE OF
More informationInt.j.pathol.2016;14(4): Original Article
Original Article Clinical Manifestations of Dengue in a Recent Outbreak in Muzaffarabad *Abdul Khalid Awan, Imtiaz Ahmed, Ashfaque Ahmed, Khusheed Lone, Robina Rafique, Raza Manzoor Haidri and Muhammad
More informationClinical Profile and Outcome of Dengue Fever from a Tertiary Care Centre at Aurangabad Maharashtra India: An Observational Study
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-issn: 2279-0853, p-issn: 2279-0861.Volume 13, Issue 9 Ver. VII (Sep. 2014), PP 14-19 Clinical Profile and Outcome of Dengue Fever from a Tertiary
More informationDENGUE FEVER; HEPATIC INVOLVEMENT IN CHILDREN UPTO 12 YEARS OF AGE
The Professional Medical Journal DOI: 10.17957/TPMJ/17.4096 DENGUE FEVER; HEPATIC INVOLVEMENT IN CHILDREN UPTO 12 YEARS OF AGE ORIGINAL PROF-4096 1. FCPS, Senior Registrar of Pediatric Medicine Holy Family
More informationLiver Involvement Associated with Dengue Infection During A Major Outbreak in Central Nepal
Liver Involvement Associated with Dengue Infection During A Major Outbreak in Central Nepal Arun Sedhain, a * Gandhi R Bhattarai, b Shital Adhikari, a Barun Shrestha, a Abja Sapkota c a Department of Medicine,
More informationRole of sonography in the assessment of dengue fever with serological correlation
International Journal of Research in Medical Sciences Basawaraj NG et al. Int J Res Med Sci. 2015 Nov;3(11):3131-3136 www.msjonline.org pissn 2320-6071 eissn 2320-6012 Research Article DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20151150
More informationStudy of Clinical Profile of Dengue Fever: An Institutional Based Prospective Study
Original article: Study of Clinical Profile of Dengue Fever: An Institutional Based Prospective Study Dr. Nitin Jain Assistant Professor, Department of General Medicine, Dr. Pinnamaneni Siddhartha Institute
More informationDengue fever in a tertiary care hospital
Research Article Dengue fever in a tertiary care hospital Tiple Nishikant 1*, Pawara Kisan 2, More S S 3 1 Assistant Professor, Department of Pediatrics, Shri.Vasantrao Naik, Government Medical College,
More informationNASRONUDIN 4/17/2013. DENVs of each type are grouped into several genotypes.
NASRONUDIN Institute of Tropical Disease, Airlangga University-Tropical and Infectious Diseases Division, Department of Internal Medicine Medical Faculty-Dr. Soetomo Hospital Disampaikan pada 14 th Jakarta
More informationDengue fever in a tertiary hospital in Makkah, Saudi Arabia
Dengue fever in a tertiary hospital in Makkah, Saudi Arabia W. Shahin a,b#, A. Nassar a,c, M. Kalkattawi a and H. Bokhari a a Internal Medicine Department, Al Noor Specialist Hospital, King Abdullah Medical
More informationClinical Features, Diagnostic Techniques and Management of Dual Dengue and Malaria Infection
ORIGINAL ARTICLE Clinical Features, Diagnostic Techniques and Management of Dual Dengue and Malaria Infection Amanullah Abbasi, Nazish Butt, Qurban Hussain Sheikh, Abdul Rabb Bhutto, S.M. Munir and Syed
More informationRESEARCH ARTICLE STUDY OF LIVER PROFILE IN DENGUE FEVER. Surendra H S*, Adarsh E, Hema.D, Varshini.P, Sirajudheen.P, Sherin Naseer
RESEARCH ARTICLE STUDY OF LIVER PROFILE IN DENGUE FEVER Surendra H S*, Adarsh E, Hema.D, Varshini.P, Sirajudheen.P, Sherin Naseer Department of Pediatrics, RRMCH, Bangalore-97 Corresponding author Dr.Surendra.H.S,
More informationDengue: A disease burden in Sri Lanka A Complex Phase III Vaccine Trial
Dengue: A disease burden in Sri Lanka A Complex Phase III Vaccine Trial Country Overview Size: 65,610 sq km Population: 21,324,791 Population growth rate: 0.904% Population: Not genetically homogeneous
More informationAn Analysis of Hematological Parameters as a Diagnostic test for Dengue in Patients with Acute Febrile Illness
Original article: An Analysis of Hematological Parameters as a Diagnostic test for Dengue in Patients with Acute Febrile Illness Dr. Chetal Suva, Dr. Yagnik Chhotala Name of Institute: Shri M. P. Shah
More informationDengue: A Practical Experience of Medical Professionals in Hospital
J MEDICINE 2012; 13 : 160-164 QUAZI TARIKUL ISLAM 1, ARIFUL BASHER 2, ROBED AMIN 3 Abstract: Background: Dengue remains endemic and frequently intensifies into epidemics in Bangladesh since 2000 resulting
More informationOutpatient dengue management
Outpatient dengue management Dr David Lye FRACP, FAMS Senior consultant Institute of Infectious Diseases and Epidemiology, Communicable Diseases Centre, Tan Tock Seng Hospital Associate professor Yong
More informationFinal Term Project Report
Final Term Project Report CRP-514 A GIS Approach to Generating a Dengue Risk Map at Shabwah Governorate BY Mohammad Habtoor ID # 200804200 Mohammed AL-Mehdhar ID # 200804340 SUBMITTED TO Professor: Dr.
More informationComparison between serological & molecular methods for diagnosis of dengue fever and its correlation with duration of illness
Original article Comparison between serological & molecular methods for diagnosis of dengue fever and its correlation with duration of illness Prashant Gangurde, Anjali Swami, Jayanthi Shastri Name of
More informationDetection of NS1 antigen, IgM antibody for the diagnosis of dengue infection in patients with acute febrile illness
International Journal of Research in Medical Sciences Neralwar A et al. Int J Res Med Sci. 2015 Oct;3(10):2826-2830 www.msjonline.org pissn 2320-6071 eissn 2320-6012 Research Article DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20150833
More informationPrediction of severity of dengue infection in children based on hepatic involvement
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-issn: 2279-0853, p-issn: 2279-0861.Volume 17, Issue 8 Ver. 1 (August. 2018), PP 44-49 www.iosrjournals.org Prediction of severity of dengue infection
More informationDENGUE CASES REPORTED DURING IN A TERTIARY CARE HOSPITAL OF ISLAMABAD
Original Article DENGUE CASES REPORTED DURING 2015-17 IN A TERTIARY CARE HOSPITAL OF ISLAMABAD 1 2 3 4 Abdul Wali Khan, Shahid Hanif, Shagufta Zafar Qureshi, Zakir Hussain 1-4 Federal Government Polyclinic
More informationReview of dengue fever cases in Hong Kong during 1998 to 2005
O R I G I N A L A R T I C L E Vivien WM Chuang TY Wong YH Leung Edmond SK Ma YL Law Owen TY Tsang KM Chan Iris HL Tsang TL Que Raymond WH Yung SH Liu Key words Dengue; Dengue hemorrhagic fever; Serotyping
More informationMODULE 7: Outpatient Management
MODULE 7: Outpatient Management Dengue Clinical Management Acknowledgements This curriculum was developed with technical assistance from the University of Malaya Medical Centre. Materials were contributed
More informationCorrelation of Liver Transaminases with Platelet count in Dengue patients from Tertiary Care Hospital in Western India
International Journal of Current Research and Review DOI: 10.7324/IJCRR.2018.1053 IJCRR Section: Healthcare Sci. Journal Impact Factor 4.016 ICV: 71.54 Correlation of Liver Transaminases with Platelet
More informationCorrelation of disease spectrum among four Dengue serotypes: a five years hospital based study from India
Correlation of disease spectrum among four Dengue serotypes: a five years hospital based study from India ORIGINAL ARTICLE ABSTRACT The recognition of DF (DHF Dengue Hemorrhagic Fever) is very complicated
More informationEvaluation of Some Clinical, Humoral and Imagenological Parameters in Patients of Dengue Haemorrhagic Fever Six Months after Acute Illness
Evaluation of Some Clinical, Humoral and Imagenological Parameters in Patients of Dengue Haemorrhagic Fever Six Months after Acute Illness Daniel González*, Raiza Martínez**, Osvaldo Castro*, Teresita
More informationChikungunya Fever: Epidemiology and Clinical Syndrome in Small Infants in Honduras June-July 2015
Chikungunya Fever: Epidemiology and Clinical Syndrome in Small Infants in Honduras June-July 2015 Flora Flowers MD Emergency and Pediatric Critical Care Service Hospital Escuela Universitario 12th Congress
More informationTo study the clinical profile of dengue fever and to evolve a prognostic marker based on hematological parameters for severe dengue
International Journal of Contemporary Pediatrics Sivathanu S et al. Int J Contemp Pediatr. 7 Mar;4():8-4 http://www.ijpediatrics.com pissn 49-8 eissn 49-9 Original Research Article DOI: http://dx.doi.org/.8/49-9.ijcp77
More informationCHIKUNGUNYA VIRUS INFECTION. Cesar Ponce S. Medical Microbiologist and Parasitologist. Epidemiologist ADC Medical Microbiology Department Director
CHIKUNGUNYA VIRUS INFECTION Cesar Ponce S. Medical Microbiologist and Parasitologist. Epidemiologist ADC Medical Microbiology Department Director Curacao, Aug. 2014 TOPICS: Definition History Epidemiology
More informationDengue hemorrhagic fever outbreak in children in Port Sudan
Journal of Infection and Public Health (2011) 4, 1 6 Dengue hemorrhagic fever outbreak in children in Port Sudan Amal Malik a, Kenneth Earhart b, Emad Mohareb b, Magdi Saad b, Mubarak Saeed c, Ali Ageep
More informationInternational Journal of Health Sciences and Research ISSN:
International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571 Original Research Article The Study of Clinical Manifestations, Trend and Outcome of All Confirmed Dengue Cases Admitted
More informationThrombocytopenia, fever, rash, hypotension. Alexander D. Hristov MD University of Wisconsin Hospital and Clinic Internal Medicine PGY 2
Thrombocytopenia, fever, rash, hypotension Alexander D. Hristov MD University of Wisconsin Hospital and Clinic Internal Medicine PGY 2 Case Chief Complaint: Fever, diarrhea, bloody nose, rash HPI: 38 y/o
More informationHepatic Involvement in Dengue Fever in Children
Original Article Iran J Pediatr Jun 2012; Vol 22 (No 2), Pp: 231-236 Hepatic Involvement in Dengue Fever in Children Kalenahalli Jagadishkumar*, MBBS, MD; Puja Jain, MBBS; Vaddambal G. Manjunath, MBBS,
More information1. Dengue An Overview. Dengue Expert Advisory Group
1. Dengue An Overview Dengue Expert Advisory Group 1 Introduction Dengue Fever Dengue Hemorrhagic Fever Dengue Shock Syndrome 2 3 Dengue Virus Family : Flaviviridae Genus : Flavivirus Serotypes : DV1,
More information2 Faculty of Marine Science, Lasbela University of Agriculture, Water & Marine Sciences Uthal Balochistan, Pakistan.
Lasbela, U. J.Sci.Techl., Vol. VI, pp.124-129, 2017 ISSN 2306-8256 RESEARCH ARTICLE The Prevalence of Dengue Virus Serotypes and Dengue Cases Reported in District Peshawar Faiz-ur-Rehman 1, Atta-ur-Rehman
More informationOriginal Research Article
Original Research Article Evaluation of during an Outbreak at a Tertiary Care Hospital of South India Gayatri Manam 1, Ravi M Godavarthi 2, Ramakrishna Baru 3, Sunitha 4, Gowtham Surya Duddu 5 1 Assistant
More informationRetrospective study of clinical profile and outcome of pediatric dengue cases in a teaching hospital
International Journal of Contemporary Pediatrics Kumar AMK et al. Int J Contemp Pediatr. 2017 Jan;4(1):226-230 http://www.ijpediatrics.com pissn 2349-3283 eissn 2349-3291 Original Research Article DOI:
More informationSerotype Distribution and Demographics of Dengue Patients in a Tertiary Hospital of Lahore, Pakistan during the 2011 Epidemic
Area Based Research Serotype Distribution and Demographics of Dengue Patients in a Tertiary Hospital of Lahore, Pakistan during the 2011 Epidemic Muhammad MUNIR, Riffat MEHBOOB *, Samina NAEEM, Muhammad
More informationDengue IgM antibody sero-status assessment: a current experience in a teaching institution
International Journal of Advances in Medicine Kiran D et al. Int J Adv Med. 2017 Jun;4(3):661-665 http://www.ijmedicine.com pissn 2349-3925 eissn 2349-3933 Original Research Article DOI: http://dx.doi.org/10.18203/2349-3933.ijam20171552
More informationLiver Function Tests Abnormality and Clinical Severity of Dengue Infection in Adult Patients
Liver Function Tests Abnormality and Clinical Severity of Dengue Infection in Adult Patients Chatporn Kittitrakul MD*, Udomsak Silachamroon MD*, Weerapong Phumratanaprapin MD*, Srivicha Krudsood MD*, Polrat
More informationMATERIAL AND METHODS Study objective: To study the clinical profile and predictors of mortality in children with severe dengue.
INTERNATIONAL JOURNAL OF BIOASSAYS ISSN: 2278-778X CODEN: IJBNHY ORIGINAL RESEARCH ARTICLE OPEN ACCESS A PROSPECTIVE OBSERVATIONAL STUDY OF CLINICAL PREDICTORS OF OUTCOME IN DENGUE IN CHILDREN Sarada G,
More informationDengue Fever & Dengue Hemorrhagic Fever Annual Reports to WHO
Dengue Virus Member of the genus Flavivirus Transmitted by the Aedes mosquito; mosquito => human cycle 4 serotypes: DENV1, 2, 3, and 4 Homotypic immunity is long lasting Heterotypic immunity is short lived
More informationOriginal Article. Emergence of Chikungunya infection in North India
Original Article Emergence of Chikungunya infection in North India Malik Shruti 1, Mehta Krunal D 2 *, Singh K.P. 3 and Dhole T.N. 1 1 Department of Microbiology, SGPGIMS, Lucknow, U.P., India 2 Department
More informationClinical Profile of Dengue Infection at a Teaching Hospital in South India
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-issn: 2279-0853, p-issn: 2279-0861.Volume 16, Issue 3 Ver. II (March. 2017), PP 52-56 www.iosrjournals.org Clinical Profile of Dengue Infection
More informationMinistry of Health and Medical Services Solomon Islands. Dengue Outbreak: External Sitrep No. 3. From Epidemiological Week 33-41, 2016
Ministry of Health and Medical Services Solomon Islands Dengue Outbreak: External Sitrep No. 3 From Epidemiological Week 33-41, 2016 Summary Since August 2016, an unusual increase in dengue-like illness,
More informationClinical, Biochemical and Hematological Profile in Dengue Fever
Original Article Print ISSN: 2321-6379 Online ISSN: 2321-595X DOI: 10.17354/ijss/2016/545 Clinical, Biochemical and Hematological Profile in Dengue Fever Gorre Chandra Shekar 1, Ayyappa Amaravadi 2 1 Associate
More informationA Study on Common Etiologies of Acute Febrile Illness Detectable by Microbiological Tests in a Tertiary Care Hospital
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 7 (2016) pp. 670-674 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2016.507.076
More informationInternational Journal of Scientific & Engineering Research Volume 9, Issue 4, April ISSN
International Journal of Scientific & Engineering Research Volume 9, Issue 4, April-2018 718 The importance of monitoring haematologic changes, thrombocytopenia and monocytosis in dengue haemorrhagic fever
More information