THE BASICS OF EBD. Elliot Abt, D.D.S., M.S., M.Sc. Advocate Illinois Masonic Medical Center
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1 THE BASICS OF EBD Elliot Abt, D.D.S., M.S., M.Sc. Advocate Illinois Masonic Medical Center
2 Topics EBD vs. traditional approach to decisions Clinical examples Hierarchy of evidence Problems with published research
3 Defining Evidence-Based Dentistry Evidence-based dentistry (EBD) is an approach to oral health that requires the judicious integration of systematic assessments of clinically relevant scientific evidence, relating to the patient s oral and medical condition and history, with the dentist s clinical expertise and the patient s treatment needs and preferences.
4 Research Evidence Clinical Experience Patient Preferences Evidence-based decisions
5 Condition A Treatment B Outcome C Traditional decisions
6 Dental School Rules All endo teeth need posts/crowns All missing teeth must be replaced All cases mounted in centric relation Border mould / face-bow / split-cast a must!! Never use cantilevers Chronic irritation leads to malignant transformation
7 Example 1 Bounded Edentulous Spaces
8 Traditional Approach All missing teeth must be replaced to restore function and to avoid arch collapse.
9 EB Approach
10 EB Approach Implant vs. fixed bridge survival
11 EB Approach Implant vs. fixed bridge survival Partial edentulism is a condition, rather than a pathologic entity
12 EB Approach Implant vs. fixed bridge survival Partial edentulism is a condition, rather than a pathologic entity No treatment leads to a minor self-limiting movement of teeth within first year postextraction
13 Treatment Options
14 Treatment Options 3-unit fixed bridge
15 Treatment Options 3-unit fixed bridge Single-tooth implant
16 Treatment Options 3-unit fixed bridge Single-tooth implant Removable prosthesis
17 Treatment Options 3-unit fixed bridge Single-tooth implant Removable prosthesis No treatment!!
18 Example 2 Amalgam versus composite
19 Research Evidence
20 Research Evidence On occlusal surface, both restoratives have good outcomes
21 Research Evidence On occlusal surface, both restoratives have good outcomes With inter-proximal and multi-surface lesions, risk of secondary caries is higher with composite as compared with amalgam
22 Research Evidence On occlusal surface, both restoratives have good outcomes With inter-proximal and multi-surface lesions, risk of secondary caries is higher with composite as compared with amalgam Fracture rates appear to be similar with both restoration types
23 Inter-proximal lesions
24 Inter-proximal lesions Does the patient have a high caries index?
25 Inter-proximal lesions Does the patient have a high caries index? Is the lesion sub-gingival?
26 Inter-proximal lesions Does the patient have a high caries index? Is the lesion sub-gingival? Is there enamel at the gingival margin?
27 Inter-proximal lesions Does the patient have a high caries index? Is the lesion sub-gingival? Is there enamel at the gingival margin? Is the lesion on a bicuspid or molar?
28
29
30
31 Example 3: Good Evidence Not Being Used Appropriately
32 Example 3: Good Evidence Not Being Used Appropriately SEALANTS!!!
33 Example 3: Good Evidence Not Being Used Appropriately SEALANTS!!!
34 Example 3: Good Evidence Not Being Used Appropriately SEALANTS!!! FLUORIDE!!!
35 Example 3: Good Evidence Not Being Used Appropriately SEALANTS!!! FLUORIDE!!!
36 Evidence-based Dentistry Because each patient is unique, research evidence should help guide, rather than dictate clinical decision making.
37 5-step process 1. develop a focused clinical question (PICO) 2. search for evidence 3. critically appraise the evidence 4. apply evidence to patient question/ circumstance 5. evaluate
38 3 Questions to Keep in Mind What are the results? Are the results valid? Are the results relevant to my patients/ practice?
39 Evidence Pyramid
40 Research Design Systematic Reviews/ Meta-analysis Randomized Controlled Trials Cohort Case-Control Cross-sectional Case Series Narrative Review Opinion
41 Research Design Cohort Study Randomized Controlled Trials Case-Control Study Cross-sectional Study Case Series
42 Research Design Cohort Study Randomized Controlled Trials Interventional design Case-Control Study Cross-sectional Study Case Series
43 Research Design Cohort Study Randomized Controlled Trials Interventional design Case-Control Study Cross-sectional Study Case Series Observational designs
44 Research Design Systematic Reviews/ Meta-analysis Randomized Controlled Trials Cohort Case-Control Cross-sectional Case Series Animal Studies In-vitro Studies
45 Research Design Systematic Reviews/ Meta-analysis Randomized Controlled Trials Therapy/Prevention Cohort Case-Control Cross-sectional Case Series Animal Studies In-vitro Studies
46 Research Design Systematic Reviews/ Meta-analysis Randomized Controlled Trials Therapy/Prevention Cohort Prognosis Case-Control Cross-sectional Case Series Animal Studies In-vitro Studies
47 Research Design Systematic Reviews/ Meta-analysis Randomized Controlled Trials Therapy/Prevention Cohort Prognosis Case-Control Risk factor/rare diseases Cross-sectional Case Series Animal Studies In-vitro Studies
48 Research Design Systematic Reviews/ Meta-analysis Randomized Controlled Trials Therapy/Prevention Cohort Prognosis Case-Control Risk factor/rare diseases Cross-sectional Prevalence Case Series Animal Studies In-vitro Studies
49 Research Design Systematic Reviews/ Meta-analysis Randomized Controlled Trials Therapy/Prevention Cohort Case-Control Risk factor/rare diseases Cross-sectional Case Series Prognosis Prevalence Complication/Unusual finding Animal Studies In-vitro Studies
50 Research Design Narrative Review Systematic Review
51 Research Design Narrative Review Systematic Review Broad topic Few inclusion criteria Susceptible to bias Non-reproducible
52 Research Design Narrative Review Broad topic Few inclusion criteria Susceptible to bias Non-reproducible Systematic Review Narrow topic Exhaustive literature search Strict inclusion/exclusion criteria Reproducible
53 Meta-analysis
54 Meta-analysis Statistical pooling of data from multiple studies - why do we need to do this?
55 Meta-analysis Statistical pooling of data from multiple studies - why do we need to do this? Increases power & precision, answers questions, settles controversies
56 Meta-analysis Statistical pooling of data from multiple studies - why do we need to do this? Increases power & precision, answers questions, settles controversies Only if comparing apples with apples
57 Forest Plot
58 I Don t Have Time to Read All This!! Critical Summaries EB Treatment Recommendations
59 Keeping up with the literature
60
61 The holy grail of published research is
62 The holy grail of published research is P < 0.05
63
64 P<0.05 Positive Study the treatment works
65 P<0.05 Positive Study the treatment works
66 P<0.05 Positive Study the treatment works P>0.05 Negative Study the treatment doesn t work
67 P<0.05 Positive Study the treatment works P>0.05 Negative Study the treatment doesn t work
68 The null hypothesis Observe things in nature Do an observational study Do a randomized controlled trial
69 Beta-carotene & cardiovascular mortality
70 Summary
71 Summary Evidence-based dentistry is an approach to improving patient care through decision making
72 Summary Evidence-based dentistry is an approach to improving patient care through decision making Incorporates research evidence, along with clinical expertise and patient preferences.
73 Summary Evidence-based dentistry is an approach to improving patient care through decision making Incorporates research evidence, along with clinical expertise and patient preferences. Research evidence should help guide, rather than dictate, clinical decisions.
74 Thank You!
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