Guided Tissue and Bone Regeneration

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1 Guided Tissue and Bone Regeneration One toolbox for your needs!

2 Tefguide x24 mm pc 1 Osgide x 20 mm pc 1 Osbone μm 0.25 cc 5 Product Specifications Non-resorbable membrane and foil REF. No. Size Content Packsize Ti-Foil Resorbable membranes Epi-Guide x30 mm pc x60 mm pc x24 mm pcs x 30 mm pcs μm pc μm pc x 30 mm pc x 30 mm pc x 40 mm pc 1 CollaGuide x 20 mm pc x 30 mm pc x 40 mm pc 1 Haemostypticum stypro Cubus x 10 x 10 mm pcs 30 Resorbable fixation system Inion Tack System Tacks / 1 Drill / 1 Applicator pc Tacks pc 1 Non-resorbable fixation system Ti-System Titanium Top pc 1 Toolholder pc 1 Screwdriver pc 1 Steril box for 15 Pins pc 1 Pins mm pcs mm pcs mm pcs mm pcs 10 Resorbable, pure-phase β-tricalcium phosphate CERASORB M μm 0.5 cc μm 0.5 cc μm 1.0 cc μm 1.0 cc μm 2.0 cc μm 0.5 cc μm 1.0 cc μm 1.0 cc μm 2.0 cc 5 CERASORB Mouldable Foam x 12 x 4 mm 0,5 cc x 12 x 4 mm 1,2 cc x 25 x 4 mm 2,5 cc x 50 x 4 mm 5,0 cc 1 CERASORB Paste g / cm³ 0,5 cc g / cm³ 1,0 cc 1 Biomimetic hydroxyapatite ceramic μm 0.5 cc μm 0.5 cc μm 1,0 cc μm 1,0 cc μm 1,0 cc μm 1,0 cc μm 2,0 cc 1 2 One toolbox for your needs!

3 Predictable growth of new tissue and bone Choices for your GTR/GBR procedures! 0+ Biological compatibility 0+ Barrier function 0+ Tissue integration 0+ Easy to use % biomimetic, safe, non-organic, bone regeneration material 1, % phase purity 1,2 0+ Completely and evenly resorbed 3 0+ Osteoconductive Guided tissue regeneration Non-resorbable membranes and foils Tefguide, Ti-Foil Resorbable membranes Epi-Guide, CollaGuide, Osgide Haemostypticum stypro Guided bone regeneration CERASORB M CERASORB Foam 1 CERASORB Paste 2 Fixation systems Resorbable Inion Tack System Bone integration Osbone Non-resorbable Ti-System 0+ Quick and precise handling 0+ Reliable positioning 0+ Smooth healing without irritation 0+ Available as a set and as single units 0+ High degree of purity 0+ Long-lasting volume stability 0+ Optimal osteoconductive scaffold 0+ 80% porosity 1. CERASORB Foam contains porcine collagen material 2. CERASORB Paste contains hyaluronic acid matrix 3. Trisi P, Rao W, Rebaudi A, Fiore P (2003): Histologic Effect of Pure-Phase Beta-Tricalcium Phosphate on Bone Regeneration in Human Artifical Jawbone Defects. The International Journal of Periodontics & Restorative Dentistry, 2003, 23 (1): 69 One toolbox for your needs! 3

4 Guided tissue regeneration Non-resorbable membrane and foil Tefguide Non-resorbable PTFE membrane Tefguide is a very thin polytetrafluoroethylene (PTFE) membrane with high stability. It was developed especially for procedures where primary closure is not possible. Tefguide provides excellent healing support for new epithelial tissue growth. Due to its biologically inert structure, Tefguide is resistant to bacterial colonization. Ti-Foil Non-resorbable titanium foil Titanium is a safe and proven material in all areas of surgery. Due to the stability of the Ti-Foil, micro movements of the regeneration material can be avoided. The Ti-Foil is impermeable and delivers excellent results, even in an exposed position. Guided tissue regeneration Resorbable membranes Epi-Guide Resorbable polylactic acid (PLA) membrane Epi-Guide is a resorbable, three layer membrane. It is suitable for use in periodontology. Epi-Guide is hydrophilic and has a patented multilayer architecture of different pore cavities. Its three-dimensional constructed density gradient is designed to attract and stabilize fibroblasts and epithelial cells. Acting as a space maker, it promotes the growth of bone and periodontal supporting tissue. 4 One toolbox for your needs!

5 Properties 0+ Strong and stable structure 0+ Easy removal 0+ No bacterial colonization 0+ Effective barrier function Indications: Ideal for single tooth extraction, defects where primary closure is not possible and procedures where soft tissue regeneration is needed. Properties 0+ Bioelectrically neutral 0+ Available in thicknesses of 20 μ and 40 μ 0+ Suitable for three-dimensional augmentation 0+ Tailor-made fixation system available Indications: Application in guided bone regeneration (GBR), especially in three-dimensional bone reconstruction. Properties 0+ Extended barrier function 0+ Three layer structure 0+ High absorption capacity 0+ Textured surface Indications: Periodontal defects, long-term grafting procedures, and furcation defects. One toolbox for your needs! 5

6 Guided tissue regeneration Resorbable membranes Osgide Elastic resorbable collagen membrane Osgide is the membrane of choice for any periodontist. It is designed with easy handling and guided tissue regeneration capacities in mind. Osgide provides excellent healing support and promotes selective tissue communication, thus increasing the bone formation. CollaGuide Resorbable collagen membrane CollaGuide, a natural collagen membrane (type 1 collagen) with high resilience, designed to suit surgical procedures that need long-term barrier function. CollaGuide is a very thin and transparent membrane, free of additional chemicals (not chemically crosslinked). These product characteristics promote healing, free of inflammation and homogeneous resorption. 4 Haemostypticum stypro Haemostypticum stypro is an absorbable, topical hemostatic sponge. The gelatin sponge accelerates clot formation by enhancing platelet aggregation. The blood components interact with the enlarged surface of the sponge and the secretions of the wound are soaked through the porous structure. stypro provides a safe, effective and comfortable platform for hemostasis, control of blood coagulation, wound management, tissue repair and natural wound healing. 4. Wang H. Carroll W. Guided bone regeneration using bone grafts and collagen membranes. Quintessence International. 32, 2001; One toolbox for your needs!

7 Properties + Exceptional handling characteristics + Easy to stretch and suture + Supports formation of new blood vessels + Hydration within seconds Indications: Guided tissue regeneration (GTR), periodontal defects, socket preservation, protection of the Schneider s membrane during sinus lift procedures. Properties + Extended barrier function + Transparent structure + Homogenous resorption + Easy pin fixation Indications: Reconstruction of three-dimensional defects, long-term grafting procedures. Properties + High porosity + Complete resorption within 3 4 weeks + High absorption capacity + Single use pack Indications: dentoalveolar surgery and extraction of teeth (also in patients with risk of hemorrhages), regeneration of mucosal tissues removal of mandibular cysts, surgical removal of oral tumors and leucoplakias, surgical treatment of periapical and dental abscesses and maxillofacial surgery. One toolbox for your needs! 7

8 Fixation System Resorbable pin fixation system Inion Tack System Resorbable pin fixation system The resorbable Inion tacks provide a simple way to secure membranes safely, quickly and easily for bone augmentation surgery. They are available as a set with drill and applicator, as well as without accessories. Fixation System Non-resorbable pin fixation system Ti-System Non-resorbable pin fixation system Ti-System offers a convenient solution for safe, fast and easy fixation of all foils and membranes for bone augmentation surgery as well as their safe, fast and easy removal. The titanium pins assure a reliable positioning and fixation of the membranes and foils. The included Steribox serves for storage and sterilization as well as placement in the setting instrument and is an important component of the Ti-System. All parts of the Ti-System can be ordered individually; the pins are available in both, a 5-units and 10-units pack. 8 One toolbox for your needs!

9 Properties + Simple option for securing all membranes to bony environment + Quick and easy handling + Single-use application instrument included + No need for a second removal procedure Indication: Membrane fixation Properties + Pin fixation and revision instrumentation + All parts available separately + 3 mm pins for normal bone conditions + 5 mm pins for soft bone conditions Indication: Membrane and foil fixation One toolbox for your needs! 9

10 Guided bone regeneration Resorbable, pure-phase β-tricalcium phosphate CERASORB Product Line Bone regeneration The CERASORB product family are bone regeneration materials for the treatment of bone defects caused by trauma or disease. All CERASORB products resorb completely and evenly in the context of bone regeneration. They are referenced as the worldwide ICDD 5 standard. CERASORB comes as a modular toolbox: CERASORB M granules, CERASORB Foam and CERASORB Paste. Bone integration Biomimetic hydroxyapatite ceramic Osbone Bone integration Osbone is a synthetic, open-cell cancellous bone graft material for filling bone defects and augmentation of the atrophied alveolar ridge. This volume-stable product, which is slowly resorbed by bone, thus provides a perfect scaffolding for rapid and maximally stable bone replacement. Compared to materials of biological origin, Osbone, as a purely biomimetic material, eliminates laborious treatment with alkali and heat for the removal of organic components. 5. ICDD - International Center for Diffraction Data, Pennsylvania, USA 10 One toolbox for your needs!

11 Properties + 100% biomimetic, safe, non-organic, bone regeneration material 1,2 + 99% phase purity (ICDD reference standard) 1,2,5 + Completely and evenly resorbed 3 + Osteoconductive Properties + 100% biomimetic, safe, non-organic, bone replacement material + Scaffold principle + 80% porosity + Immediate start of osseointegration, which is completed after approx. 3 6 months 1. CERASORB Foam contains porcine collagen material 2. CERASORB Paste contains hyaluronic acid matrix 3. Trisi P, Rao W, Rebaudi A, Fiore P (2003): Histologic Effect of Pure-Phase Beta-Tricalcium Phosphate on Bone Regeneration in Human Artifical Jawbone Defects. The International Journal of Periodontics & Restorative Dentistry, 2003, 23 (1): ICDD International Center for Diffraction Data, Pennsylvania, USA One toolbox for your needs! 11

12 curasan AG Lindigstraße Kleinostheim Germany Tel.: / Fax: / _08_2017_01 The specifications on the inserts enclosed with curasan products are binding.

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