Rosacea. This non promotional presentation has been sponsored and developed by Galderma for UK healthcare professionals only.
|
|
- Paul Carter
- 5 years ago
- Views:
Transcription
1 Rosacea [Speaker Name] [Title] This non promotional presentation has been sponsored and developed by OTH DOP: September 2018 Learning Objectives To review current guidelines for best practice in diagnosis and management of rosacea To distinguish different sub types and phenotypes To evaluate the psychological aspects of living with rosacea To recognise when to refer Pre-Quiz 1 1. What part of facial skin in rosacea is commonly affected? 2. In what age group is rosacea commonly seen? 3. Is rosacea more common in males or females? 4. What is the most common rosacea trigger? 5. List 3 potential psychological aspects of rosacea 1
2 Pre-Quiz 2 1. What would be a common primary feature seen on clinical examination? 2. What type of secondary feature may be present? 3. In rosacea, thickening of the skin and enlarged pores is termed as what? 4. In ocular rosacea what common symptoms may a patient experience? 5. Cite 4 patients types with rosacea who should be referred Background Rosacea is a common and chronic inflammatory disorder, affecting the cheeks, nose, chin and forehead 1 Clinical features include flushing, erythema, papules and pustules, telangiectasias, dryness, burning, edema, or skin thickening 2 Many patients have >1 of these clinical features 3 There is no diagnostic test for rosacea 4 1. Del Rosso JQ, et al. Cutis. 2013;91(3 Suppl): NICE CKS 3. Tan J, et al. Br J Dermatol. 2013;169(3): Tan J; ROSCO coauthors. Br J Dermatol. 2017;177(2): Epidemiology 1 Rosacea most commonly affects people aged years More prevalent in fair-skinned people of northern and western European descent More common in women, but tends to be more severe in men A proportionately larger number of men may also develop phymatous changes The prevalence of acne rosacea varies up to >20%, depending on populations studied and methodological approach used Rosacea affects 1/10 people in the UK 1. NICE CKS 2
3 Subtype 1 Erythematotelangiectatic Subtype 2 Papulopustular Subtype 3 Phymatous Subtype 4 Ocular Pathogenesis 1 The pathophysiology of rosacea has yet to be fully determined. Theories include: Genetic Environmental - chronic exposure to UV Immune response innate and adaptive Microorganisms Vascular and inflammatory factors 2 1. Tan J; et al. Br J Dermatol. 2017;177(2): Gerber PA,et al. J Investig Dermatol Symp Proc. 2011;15(1): Clinical Features 1 Rosacea s diverse features may be part of a continuum of inflammation Common presentations of flushing and fixed centrofacial erythema may progress to include papules and pustules and potentially phymas Erythema and flushing often remain in patients successfully treated for their papules and pustules 3
4 Assessment and Diagnosis 1 Current diagnostic practice follows 2002 recommendations from the National Rosacea Society (NRS) expert panel Identified a number of primary features and secondary features Subtypes classification grouping common presentations into 4 subtypes 1. Wilkin J, et al. J Am Acad Dermatol. 2002;46(4): National Rosacea Society (NRS) Diagnostic Criteria 1 Primary Features Flushing (transient erythema) Nontransient erythema Papules and pustules Telangiectasia Secondary Features Burning or stinging Plaque Dry appearance Oedema Ocular manifestations Peripheral location Phymatous changes 1. Wilkin J, et al. J Am Acad Dermatol. 2002;46(4): National Rosacea Society (NRS) Diagnostic Subtypes 1 Subtype 1 Subtype 2 Erythematotelangiectatic Papulopustular Flushing and persistent central facial erythema +/-telangiectasia Sparing of periocular and nasolabial region Oedema, stinging/ burning, scaling may be present Central facial erythema and telangiectasia Transient pustules and/or papules present centrally or peri-orally. Frequently associated burning/ stinging 1. Wilkin J, et al. J Am Acad Dermatol. 2002;46(4):
5 2002 National Rosacea Society (NRS) Diagnostic Subtypes 1 Subtype 3 Subtype 4 Phymatous Ocular Thickening skin, irregular surface nodularities with enlargement and prominent pores Tissue hyperplasia Typically on the nose (Rhinophyma) Males > females 10:1 Burning, stinging, dryness Foreign-body sensation Eye photosensitivity, itching, blurred vision Telangiectasia of conjunctiva + lid margin, stye, infections. Lid/periocular erythema Blephritis, conjunctivitis 1. Wilkin J, et al. J Am Acad Dermatol. 2002;46(4): ROSCO Panel Guidance 1 The Global ROSacea COnsensus (ROSCO) Panel Classification of rosacea based on disease phenotype rather than subtype Established importance of assessing the patient burden of rosacea 1. Tan J; ROSCO coauthors. Br J Dermatol. 2017;177(2): ROSCO Phenotype v. Subtype 1 Rosacea features can span multiple subtypes Subtype based assessment may not fully address the range of clinical features Phenotype based diagnosis and severity grading helps facilitate an individualised disease management plan 1. Tan J; ROSCO coauthors. Br J Dermatol. 2017;177(2):
6 ROSCO Phenotype v. Subtype 1 Potential overlap of rosacea features with subtype classification: ETR PPR Phymatous Ocular Facial erythema (transient and persistent) Telangiectasia Inflammatory lesions (papules/pustules) Phymatous changes Adapted from Tan J; 2017 Ocular symptoms 1. Tan J; ROSCO coauthors. Br J Dermatol. 2017;177(2): National Rosacea Society (NRS) Diagnostic Criteria 1 A diagnosis of rosacea may be considered in the presence of 1 of the following diagnostic cutaneous signs: Fixed centrofacial erythema in a characteristic pattern Phymatous changes Primary Phenotypes Papules and pustules Flushing Telangiectasia Ocular Secondary Phenotypes Burning or stinging Facial oedema Dry appearance 2017 National Rosacea Society (NRS) Assessment Scales 1 Phenotypes Papules and pustules Flushing Telangiectasia Persistent erythema Assessment Scale Lesion counts, IGA FAST, GFSS None CEA/PSA CEA, Clinician s Erythema Assessment; FAST, Flushing Assessment Tool; GFSS, Global Flushing Severity Score; IGA, Investigator s Global Assessment; PSA, Patient s Self-Assessment. 6
7 Exacerbating Factors Exposure to extremes of Sun exposure 1 Hot beverages 1 Spicy foods 1 temperature 1 Alcohol 1 Exercise 2 Skin barrier disruption 2 Emotional stress 1 Irritation from topical products 2 Psychologic feelings, especially anger, rage, and embarrassment 3 Certain drugs such as nicotinic acid and vasodilators (eg, calcium-channel blockers) 1 1. NICE. CKS. Rosacea Mikkelsen, et al. Dermatol Reports. 2016;8(1): Drake L. National Rosacea Society. In: Rosacea Review. Winter Triggers 1 Sun exposure Emotional stress Hot weather Wind Heavy exercise Alcohol consumption Hot baths Cold weather Spicy foods Humidity Certain skin care products Indoor heat Heated beverages Certain cosmetics 27% 57% 56% 52% 51% 46% 45% 44% 41% 41% 36% 75% 81% 79% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 1. Adapted from: NRS. Psychosocial Aspects 1 Rosacea has an adverse impact on emotional, social, and occupational well-being Psychologic burden includes depression, anxiety, and worry Scales include the Rosacea Quality of Life Index (RosaQoL) 7
8 Primary Care Dermatology Society (PCDS) Guidance Rosacea 1 Product Flushing, Erythema & Telangiectasia Papules & Pustules Occular Ivermectin 1% Cream +++ Azelaic Acid Gel ++ Metronidazole Gel or Cream 0.75% + Brimonidine Gel 0.33% ++ Eye Lubricants +++ Doxycycline MR 40mg +++ Doxycycline 100mg Lymecycline 408mg caps Oxytetracycline mg + + Erythromycin/Clarithromycin mg + Isotretinoin ++ Intense Pulsed Light (IPL) +++ Pulsed Dye Laser (PDL) ++ Clonidine 25-50mcg ++ Propranolol 10-40mg + Carvedilol mg + Legend +++ Strong recommendation ++ Moderate recommendation + Low recommendation Individual Summaries of Product Characteristics (SPCs) must be consulted prior to prescribing. 1. PCDS Guidance: Rosacea Treatment Options Available at Self Care 1 Provide patient with BAD PIL Protect skin with perfume-free sun block Avoid rubbing or scrubbing the face Avoid perfumed soaps Avoid exacerbating factors Generally emollients are soothing Use an unperfumed moisturiser on a regular basis 1. BAD. Patient Education The following may improve the effectiveness of provider-patient encounters and the outcome of therapy: Rosacea characteristics Details of skin-care regimens Avoidance of triggers Medical and self-care treatment choices Adherence to therapy Correct use of medications 8
9 When to Refer Severe psychological distress 1 Severe ocular involvement (to ophthalmologist) 2 Patient might benefit from Intense Pulsed Light (IPL) or Pulsed Dye Laser (PDL) - limited NHS availability 1 Not responding to treatment 1 Surgical reduction for bulbous phymatous rosacea 2 1. PCDS Guidelines: Rosacea Treatment Options, Available at 2. BAD. In Summary Rosacea is a common and chronic inflammatory disorder, affecting the cheeks, nose, chin and forehead 1 Rosacea most commonly affects people aged years and women 2 Clinical features include flushing, erythema, papules and pustules, telangiectasias, dryness, burning, oedema, or skin thickening 2 Many patients have >1 of these clinical features 3 There is no diagnostic test for rosacea 4,5 Rosacea has an adverse impact on emotional, social, and occupational well-being 6 1. Del Rosso JQ, et al. Cutis. 2013;91(3 Suppl): NICE CKS 3. Tan J, et al. Br J Dermatol. 2013;169(3): Forton FM et al. Acta Derm Venereol. 2017;97(2): Tan J; ROSCO coauthors. Br J Dermatol. 2017;177(2): Gallo RL, et al. J Am Acad Dermatol. 2018;78(1): Pre-Quiz 1 1. What part of facial Cheeks, forehead, chin skin in rosacea is and nose. commonly affected? 1 2. In Middle what aged group 3. Is rosacea more individuals is rosacea (30-50 common Females. in males commonly years of age). seen? or females? 4. What is the most Sun common exposure. 3 rosacea trigger? Rosacea has an adverse 5. impact List 3 on potential emotional, social, and occupational psychological well-being, caused by depression, aspects of anxiety, rosacea and worry Del Rosso JQ, et al. Cutis. 2013;91(3 Suppl): NICE CKS 3. NRS 4. Gallo RL, et al. J Am Acad Dermatol. 2018;78(1):
10 Pre-Quiz 2 Fixed centrofacial 1. What would be a erythema, Phymatous changes, common Papules primary and feature pustules, seen Flushing, on Telangiectasia, clinical examination? Ocular manifestations. 1 Secondary 2. What type of phenotypes: Burning secondary or stinging; Facial feature oedema; may Dry be present? appearance; Ocular manifestations In rosacea, thickening of the skin and Phymatous. enlarged pores 1 is termed as what? 4. Lid In margin ocular telangiectases; rosacea Interpalpebral conjunctival what common injection; Spade-shaped infiltrates symptoms in the may cornea; a patient Scleritis experience? and sclerokeratitis. 1 Severe psychological distress; 5. Cite 4 patients Not responding to treatment; Patient types might with benefit rosacea from IPL)or who PDL) should Severe be ocular referred involvement; bulbous phymatous rosacea. 2 2 PCDS Guidelines: Rosacea Treatment Options, Available at Case Studies* *all case studies presented are fictional for demonstrative purposes Case 1 58 year old female Celtic origin Fixed redness across cheeks, nose and chin Embarrassed Distressed by preconceptions Skin very sensitive 10
11 2017 National Rosacea Society (NRS) Diagnostic Criteria 1 A diagnosis of rosacea may be considered in the presence of 1 of the following diagnostic cutaneous signs: Fixed centrofacial erythema in a characteristic pattern Phymatous changes Primary Phenotypes Papules and pustules Flushing Telangiectasia Ocular Secondary Phenotypes Burning or stinging Facial oedema Dry appearance Triggers 1 Sun exposure Emotional stress Hot weather 75% 81% 79% Wind Heavy exercise Alcohol consumption Hot baths 57% 56% 52% 51% Cold weather Spicy foods Humidity Certain skin care products Indoor heat 46% 45% 44% 41% 41% Heated beverages 36% Certain cosmetics 27% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 1. Adapted from: NRS. Primary Care Dermatology Society (PCDS) Guidance Rosacea 1 Product Flushing, Erythema & Telangiectasia Papules & Pustules Occular Ivermectin 1% Cream +++ Azelaic Acid Gel ++ Metronidazole Gel or Cream 0.75% + Brimonidine Gel 0.33% ++ Eye Lubricants +++ Doxycycline MR 40mg +++ Doxycycline 100mg Lymecycline 408mg caps Oxytetracycline mg + + Erythromycin/Clarithromycin mg + Isotretinoin ++ Intense Pulsed Light (IPL) +++ Pulsed Dye Laser (PDL) ++ Clonidine 25-50mcg ++ Propranolol 10-40mg + Carvedilol mg + Legend +++ Strong recommendation ++ Moderate recommendation + Low recommendation Individual Summaries of Product Characteristics (SPCs) must be consulted prior to prescribing. 1. PCDS Guidance: Rosacea Treatment Options Available at 11
12 Case 2 62 year old female Presents with multiple papules and a few pustules None of the medicines the GP has prescribed have had any benefit Seeking a dermatology referral Embarrassed by her facial appearance and affecting her Quality of Life (QOL) 2017 National Rosacea Society (NRS) Diagnostic Criteria 1 A diagnosis of rosacea may be considered in the presence of 1 of the following diagnostic cutaneous signs: Fixed centrofacial erythema in a characteristic pattern Phymatous changes Primary Phenotypes Papules and pustules Flushing Telangiectasia Ocular Secondary Phenotypes Burning or stinging Facial oedema Dry appearance Primary Care Dermatology Society (PCDS) Guidance Rosacea 1 Product Flushing, Erythema & Telangiectasia Papules & Pustules Occular Ivermectin 1% Cream +++ Azelaic Acid Gel ++ Metronidazole Gel or Cream 0.75% + Brimonidine Gel 0.33% ++ Eye Lubricants +++ Doxycycline MR 40mg +++ Doxycycline 100mg Lymecycline 408mg caps Oxytetracycline mg + + Erythromycin/Clarithromycin mg + Isotretinoin ++ Intense Pulsed Light (IPL) +++ Pulsed Dye Laser (PDL) ++ Clonidine 25-50mcg ++ Propranolol 10-40mg + Carvedilol mg + Legend +++ Strong recommendation ++ Moderate recommendation + Low recommendation Individual Summaries of Product Characteristics (SPCs) must be consulted prior to prescribing. 1. PCDS Guidance: Rosacea Treatment Options Available at 12
13 Case 3 49 year old lady Eyes dry with stinging sensation Eyes appear red and feel like there is something in them Sometimes vision appears blurry Has redness on both cheeks, forehead and nose Otherwise fit and well 2017 National Rosacea Society (NRS) Diagnostic Criteria 1 A diagnosis of rosacea may be considered in the presence of 1 of the following diagnostic cutaneous signs: Fixed centrofacial erythema in a characteristic pattern Phymatous changes Primary Phenotypes Papules and pustules Flushing Telangiectasia Ocular Secondary Phenotypes Burning or stinging Facial oedema Dry appearance Primary Care Dermatology Society (PCDS) Guidance Rosacea 1 Product Flushing, Erythema & Telangiectasia Papules & Pustules Occular Ivermectin 1% Cream +++ Azelaic Acid Gel ++ Metronidazole Gel or Cream 0.75% + Brimonidine Gel 0.33% ++ Eye Lubricants +++ Doxycycline MR 40mg +++ Doxycycline 100mg Lymecycline 408mg caps Oxytetracycline mg + + Erythromycin/Clarithromycin mg + Isotretinoin ++ Intense Pulsed Light (IPL) +++ Pulsed Dye Laser (PDL) ++ Clonidine 25-50mcg ++ Propranolol 10-40mg + Carvedilol mg + Legend +++ Strong recommendation ++ Moderate recommendation + Low recommendation Individual Summaries of Product Characteristics (SPCs) must be consulted prior to prescribing. 1. PCDS Guidance: Rosacea Treatment Options Available at 13
14 Case 4 68 year old man with lumps on the end of his nose Skin feels hard and thickened Embarrassed by appearance 2017 National Rosacea Society (NRS) Diagnostic Criteria 1 A diagnosis of rosacea may be considered in the presence of 1 of the following diagnostic cutaneous signs: Fixed centrofacial erythema in a characteristic pattern Phymatous changes Primary Phenotypes Papules and pustules Flushing Telangiectasia Ocular Secondary Phenotypes Burning or stinging Facial oedema Dry appearance Primary Care Dermatology Society (PCDS) Guidance Rosacea 1 Product Flushing, Erythema & Telangiectasia Papules & Pustules Occular Ivermectin 1% Cream +++ Azelaic Acid Gel ++ Metronidazole Gel or Cream 0.75% + Brimonidine Gel 0.33% ++ Eye Lubricants +++ Doxycycline MR 40mg +++ Doxycycline 100mg Lymecycline 408mg caps Oxytetracycline mg + + Erythromycin/Clarithromycin mg + Isotretinoin ++ Intense Pulsed Light (IPL) +++ Pulsed Dye Laser (PDL) ++ Clonidine 25-50mcg ++ Propranolol 10-40mg + Carvedilol mg + Legend +++ Strong recommendation ++ Moderate recommendation + Low recommendation Individual Summaries of Product Characteristics (SPCs) must be consulted prior to prescribing. 1. PCDS Guidance: Rosacea Treatment Options Available at 14
15 Case 5 27 year old woman Been applying moderate topical steroids to face for supposed eczematous rash for 4 weeks Now has more redness with some papules and pustules 2017 National Rosacea Society (NRS) Diagnostic Criteria 1 A diagnosis of rosacea may be considered in the presence of 1 of the following diagnostic cutaneous signs: Fixed centrofacial erythema in a characteristic pattern Phymatous changes Primary Phenotypes Papules and pustules Flushing Telangiectasia Ocular Secondary Phenotypes Burning or stinging Facial oedema Dry appearance PCDS Guidance Rosacea 1 Product Flushing, Erythema & Telangiectasia Papules & Pustules Occular Ivermectin 1% Cream +++ Azelaic Acid Gel ++ Metronidazole Gel or Cream 0.75% + Brimonidine Gel 0.33% ++ Eye Lubricants +++ Doxycycline MR 40mg +++ Doxycycline 100mg Lymecycline 408mg caps Oxytetracycline mg + + Erythromycin/Clarithromycin mg + Isotretinoin ++ Intense Pulsed Light (IPL) +++ Pulsed Dye Laser (PDL) ++ Clonidine 25-50mcg ++ Propranolol 10-40mg + Carvedilol mg + Legend +++ Strong recommendation ++ Moderate recommendation + Low recommendation Individual Summaries of Product Characteristics (SPCs) must be consulted prior to prescribing. 1. PCDS Guidance: Rosacea Treatment Options Available at 15
16 Top Tips for Management 1 Ensure the patient understands that there is no cure for rosacea but symptoms can be managed Discuss trigger factors - rosacea patients can improve their chances of maintaining remission by identifying and avoiding lifestyle and environmental factors that may trigger flare-ups Target treatments to presenting symptom Ask and incorporate the psychological impact the condition may have into your treatment approach Talk about skin care and the use of non-comedogenic, fragrance and perfume free products Discuss sun protection all year round factor 30+ Topical steroid preparations should be avoided Avoid long term use of oral antibiotics 6 months Individual Summaries of Product Characteristics (SPCs) must be consulted prior to prescribing. 1. Mawson R. Thank you for listening 16
Update of Rosacea. Case 1. Case 2 8/15/2017
Update of Rosacea Dr Samantha Eisman Dermatologist Sinclair Dermatology MBChB MRCP(UK) FCDerm(SA) FACD Case 1 Your 55 year old cousin calls and asks advise about her red face. What is your differential
More informationTime to Learn. 6 th March 2018 Dr. Shirin Chakera GPwSI Integrated Dermatology Service
Time to Learn 6 th March 2018 Dr. Shirin Chakera GPwSI Integrated Dermatology Service The Red Face Rosacea Acne Seborrhoeic eczema eczema Psoriasis Slapped cheek syndrome Fungal infection Erysipelas...
More informationRosacea: a symptom-based approach to management Edward Seaton MA, MRCP
Rosacea: a symptom-based approach to management Edward Seaton MA, MRCP VM Rosacea is a common skin condition of unknown aetiology. Dr Seaton describes the recommended management of the vascular and inflammatory
More informationEvidence-based Clinical Practice Guidelines for Treatment of Acne and Rosacea in Canada. Catherine Zip Nov 10, 2016
Evidence-based Clinical Practice Guidelines for Treatment of Acne and Rosacea in Canada Catherine Zip Nov 10, 2016 Acne Acne Classification Type Comedonal Mild-to-moderate papulopustular acne Severe Description
More informationRosacea Rosacea: how I hates ya! Richard Castillo, OD, DO The Oklahoma College of Optometry Northeastern State University Tahlequah, OK
Rosacea Rosacea: how I hates ya! Richard Castillo, OD, DO The Oklahoma College of Optometry Northeastern State University Tahlequah, OK Introduction Clinical Features Flushing Telangiectasia Erythema Papules
More informationRelevant Disclosures. Investigator/Consultant-Allergan. Investigator-Galderma
Rosacea Update 2018 Lawrence J Green, MD Associate Clinical Professor Department of Dermatology George Washington University School of Medicne Washington DC Relevant Disclosures Investigator/Consultant-Allergan
More informationRosacea: Rosacea is an elusive skin condition. Sufferers of Little Understood Disease May Soon Have New Treatment Options
Rosacea: Sufferers of Little Understood Disease May Soon Have New Treatment Options by G. Scott Herron, M.D., Ph.D. Rosacea is an elusive skin condition that is not well understood. Until now, there has
More informationAcne Vulgaris. This non promotional presentation has been sponsored and developed by Galderma for UK healthcare professionals only.
Acne Vulgaris [Speaker Name] [Speaker Title] This non promotional presentation has been sponsored and developed by OTH18-07-0203 DOP: August 2018 Learning Objectives Explain the pathophysiology of acne
More informationACNE. Jason M Cheyney, MPAS, PA-C Dermatologic Surgery Specialists Macon, Ga 31211
ACNE Jason M Cheyney, MPAS, PA-C Dermatologic Surgery Specialists Macon, Ga 31211 Pathogenesis of Acne Causative Factors Therapy On the horizon Approximately 45 million Americans have acne It is often
More informationCUTIS. Although recommendations on the management. Do Not Copy
Consensus Recommendations From the American Acne & Rosacea Society on the Management of Rosacea, Part 5: A Guide on the Management of Rosacea James Q. Del Rosso, DO; Diane Thiboutot, MD; Richard Gallo,
More informationClinical Study Synopsis
Clinical Study Synopsis This Clinical Study Synopsis is provided for patients and healthcare professionals to increase the transparency of Bayer's clinical research. This document is not intended to replace
More informationCorporate Medical Policy
Corporate Medical Policy Non-Pharmacologic Treatment of Rosacea File Name: Origination: Last CAP Review: Next CAP Review: Last Review: non-pharmacologic_treatment_of_rosacea 8/2005 11/2017 11/2018 11/2017
More informationAdvanced facials Week 1A T1 2016
Advanced facials Week 1A T1 2016 Sensitive skin Erythemic skin Sensitivity Characteristics Reacts to external stimuli by becoming red/blotchy More easily irritated Most often fair / red hair History of
More informationBEDFORDSHIRE AND LUTON JOINT PRESCRIBING COMMITTEE (JPC)
BEDFORDSHIRE AND LUTON JOINT PRESCRIBING COMMITTEE (JPC) September 2014 Review date: September 2017 Bulletin 204 : Brimonidine tartrate gel (Mirvaso ) for the treatment of facial erythema of rosacea in
More informationThough it represents one of the more commonly seen
The marriage of standard rosacea therapies and light-based interventions sets the bar for successful rosacea therapy. By David F. Horne, MD and Diane S. Berson, MD Though it represents one of the more
More information资料来自互联网, 仅供科研和教学使用, 使用者请于 24 小时内自行删除
Clinical dermatology Original article CED Clinical and Experimental Dermatology A comparison of metronidazole 1% cream and pimecrolimus 1% cream in the treatment of patients with papulopustular rosacea:
More informationTwo Cases of Corneal Ulcer Caused by Ocular Rosacea: Late Versus Prompt Diagnosis and Treatment
JOURNAL OF CASE REPORTS 2016;6(2):263-267 Two Cases of Corneal Ulcer Caused by Ocular Rosacea: Late Versus Prompt Diagnosis and Treatment Anandita Widya, Susiyanti Made Infection and Immunology Division,
More informationClinical indicators of rosacea progression: a topographic evaluation according to subtype and severity
Hong Kong J. Dermatol. Venereol. (2017) 25, 161-169 Original Article Clinical indicators of rosacea progression: a topographic evaluation according to subtype and severity JS Hong, G Jo, HS Park, HS Yoon,
More informationSTUDY. A Comparison of 15% Azelaic Acid Gel and 0.75% Metronidazole Gel in the Topical Treatment of Papulopustular Rosacea
A Comparison of 15% Azelaic Acid Gel and 0.75% Metronidazole Gel in the Topical of Papulopustular Rosacea Results of a Randomized Trial STUDY Boni E. Elewski, MD; Alan B. Fleischer, Jr, MD; David M. Pariser,
More informationThe legally binding text is the original French version TRANSPARENCY COMMITTEE OPINION. 18 January 2012
The legally binding text is the original French version TRANSPARENCY COMMITTEE OPINION 18 January 2012 EPIDUO, gel Tube of 30 g (CIP code: 383 814-6) Tube of 60 g (CIP code: 383 816-9) Applicant: GALDERMA
More informationPulsed Dye Laser Treatment Combined with Oral Minocycline Reduces Recurrence Rate of Rosacea
pissn 1013-9087ㆍeISSN 2005-3894 Ann Dermatol Vol. 29, No. 5, 2017 https://doi.org/10.5021/ad.2017.29.5.543 ORIGINAL ARTICLE Pulsed Dye Laser Treatment Combined with Oral Minocycline Reduces Recurrence
More informationLMMG New Medicine Recommendation
LMMG New Medicine Recommendation Brimonidine (Mirvaso ) gel for facial erythema of rosacea in adults 18 years and over LMMG Recommendation: BLACK Brimonidine gel is not recommended for use to treat symptomatic
More informationReview patient presentations and pathophysiology. Discuss Treatment options Tried and true New and upcoming. Prevention and Counselling
Speaker: Janssen Consultant: Valeant, Allergan Drinker: Stone, Pizza Port, Lost Abbey Review patient presentations and pathophysiology Discuss Treatment options Tried and true New and upcoming Prevention
More informationRosacea Management. Review Article
Review Article Received: February 23, 2016 Accepted: April 14, 2016 Published online: May 18, 2016 Rosacea Management Manal Abokwidir Steven R. Feldman Department of Dermatology, Center for Dermatology
More informationROSACEA. ETIOLOGICAL ASPECTS AND STAGING
Analele Universităţii din Oradea, Fascicula Protecţia Mediului Vol. XXVI 2016 ROSACEA. ETIOLOGICAL ASPECTS AND STAGING Bonta Marinela*, Bud Corina** *University of Oradea, Faculty of Medicine and Pharmacy,
More informationRosacea is a common, but often
Rosacea: A Common, Yet Commonly Overlooked, Condition B. WAYNE BLOUNT, M.D., M.P.H., and ALLEN L. PELLETIER, M.D. University of Tennessee Health Science Center, Memphis, Tennessee Rosacea is a common,
More informationRosacea is a chronic, inflammatory skin disease that affects primarily
The new england journal of medicine Caren G. Solomon, M.D., M.P.H., Editor Rosacea Esther J. van Zuuren, M.D. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence
More information06-May-15. Rosacea, Perioral Dermatitis, Optimizing Management,Tips and Traps
Rosacea, Perioral Dermatitis, Optimizing Management,Tips and Traps Rodney Sinclair Professor of Dermatology University of Melbourne & Epworth Healthcare 1 Predominantly erythematotelangiectatic rosacea
More information..GAL D ERMA. Swiss Summary of the Risk Management Plan for Soolantra (ivermectin cream lomg/g) Galderma International
Page 1 of7 Swiss Summary of the Risk Management Plan for Soolantra (ivermectin cream lomg/g) Galderma International Version Number: 1.0 Document Date: 16-February-2017 Page 2 of7 Summary of the Risk Management
More informationACNE. What are the aims of this leaflet?
ACNE What are the aims of this leaflet? This leaflet has been written to help you understand more about acne - what it is, what causes it, what can be done about it and where you can find out more about
More informationThursday 21 st August Skin Problems
Thursday 21 st August 2014 Skin Problems Skin Problems The Sun and the Skin Sun Damage Recognising the early signs of skin cancer The Big 3 inflammatory condi=ons Acne & Rosacea Eczema (Including Seborrhoeic
More informationX-Plain Acne Reference Summary
X-Plain Acne Reference Summary Nearly 17 million people in the United States have acne, making it one of the most common skin diseases in the USA. Although acne is not a serious health threat, severe acne
More informationOriginal Policy Date
MP 2.01.45 Non-Pharmacologic Treatment of Rosacea Medical Policy Section Medicine Issue 12:2013 Original Policy Date 12:2013 Last Review Status/Date Reviewed with literature search/12:2013 Return to Medical
More informationCutaneous rosacea: a thorough overview
32 Cutaneous rosacea: a thorough overview of pathogenesis, clinical presentations, and current recommendations on management James Q. Del Rosso Del Rosso Dermatology Research Center Las Vegas, Nevada The
More informationبالدويدات الشعرية الاجربة التهاب= Demodex folliculitis. Rosacea
Rosacea ROSACEA Despite universal recognition, rosacea remains a controversial topic in dermatology, largely because of its uncertain pathophysiology and clinical variation. Practitioners and the public
More informationF r e q u e n t l y A s k e d Q u e s t i o n s
Acne who specializes in treating skin problems) about how you can help prevent acne and if treatment would help you. Q: What is acne? A: Acne is a disorder that causes outbreaks of skin lesions commonly
More informationTreatment of Refractory Rosacea with a Dual Wavelength Long- Pulsed 755-nm Alexandrite and 1,064-nm Nd:YAG Laser
Med Laser 2018;7(1):47-51 https://doi.org/10.25289/ml.2018.7.1.47 pissn 2287-8300 ㆍ eissn 2288-0224 Treatment of Refractory Rosacea with a Dual Wavelength Long- Pulsed 755-nm Alexandrite and 1,064-nm Nd:YAG
More informationPRODUCT MONOGRAPH TABLE OF CONTENTS. p. 8 p. 12
PRODUCT MONOGRAPH PRODUCT MONOGRAPH TABLE OF CONTENTS p. 8 p. 12 2 OVERVIEW OF ROSACEA Rosacea is a chronic skin disease with a relapsing-remitting course characterized by a variable spectrum of dermatologic
More informationROSACEA IS A CHRONIC CUTAneous. Cutaneous and Ocular Signs of Childhood Rosacea STUDY
STUDY Cutaneous and Ocular Signs of Childhood Rosacea Mélanie Chamaillard, MD; Bruno Mortemousque, MD; Franck Boralevi, MD; Claudia Marques da Costa, MD; Farida Aitali, MD; Alain Taïeb, MD; Christine Léauté-Labrèze,
More informationNasolacrimal Duct Blockage
The eyelids play a key role in protecting the eyes. They help spread moisture (tears) over the surface of the eyes when they close (for example, while blinking); thus, they help prevent the eyes from becoming
More informationClinical Study Synopsis
Clinical Study Synopsis This Clinical Study Synopsis is provided for patients and healthcare professionals to increase the transparency of Bayer's clinical research. This document is not intended to replace
More informationDermatologists who keep an open mind and tailor the regimen to each individual can help steer patients toward long-term control of rosacea symptoms.
Dermatologists who keep an open mind and tailor the regimen to each individual can help steer patients toward long-term control of rosacea symptoms. By Paul Winnington, Editor-in-Chief 48 Practical Dermatology
More informationTopical Ivermectin in the Treatment of Papulopustular Rosacea: A Systematic Review of Evidence and Clinical Guideline Recommendations
Dermatol Ther (Heidelb) (2018) 8:379 387 https://doi.org/10.1007/s13555-018-0249-y REVIEW Topical Ivermectin in the Treatment of Papulopustular Rosacea: A Systematic Review of Evidence and Clinical Guideline
More informationInvasive Pulsed-Type, Bipolar, Alternating Current Radiofrequency Treatment Using Microneedle Electrodes for Nasal Rosacea
Med Laser 2017;6(1):32-36 https://doi.org/10.25289/ml.2017.6.1.32 pissn 2287-8300 ㆍ eissn 2288-0224 Invasive Pulsed-Type, Bipolar, Alternating Current Radiofrequency Treatment Using Microneedle Electrodes
More informationWe are IntechOpen, the world s leading publisher of Open Access books Built by scientists, for scientists. International authors and editors
We are IntechOpen, the world s leading publisher of Open Access books Built by scientists, for scientists 3,900 116,000 120M Open access books available International authors and editors Downloads Our
More informationAtopic Eczema with detail on how to apply wet wraps
Atopic Eczema with detail on how to apply wet wraps Dr Carol Hlela Consultant Dermatologist Head of Unit, Department of Dermatology, Paediatrics Red Cross Children s Hospital, UCT Red Cross War Memorial
More informationTreatments used Topical including cleansers and moisturizer Oral medications:
Discipline: Dermatology Extended Topic: Acne & Rosacea : Onset: Location: Face Chest Back Menses if female: Regular Irregular PCOS Treatments used Topical including cleansers and moisturizer Oral medications:
More informationA case of rosacea fulminans in a pregnant woman
Hong Kong J. Dermatol. Venereol. (2018) 26, 122-126 Views and Practice A case of rosacea fulminans in a pregnant woman JE Seol, SH Park, JU Kim, GJ Cho, SH Moon, H Kim Introduction Rosacea fulminans (RF)
More informationInteresting Case Series. Rhinophyma
Interesting Case Series Rhinophyma Jake Laun, BS, Jared Gopman, BS, Joshua B. Elston, MD, and Michael A. Harrington, MD Department of Surgery, Division of Plastic Surgery, University of South Florida Morsani
More informationTCIs are only available on prescription and are usually started by a dermatology specialist.
(TCIs) What are topical calcineurin inhibitors? Topical calcineurin inhibitors are treatments that alter the immune system and have been developed for controlling eczema. There are two types available:
More informationDD PROOFS. Acne vulgaris is a multifactorial skin disorder affecting
June 2014 611 Copyright 2014 ORIGINAL ARTICLES SPECIAL TOPIC Rapid Treatment of Mild Acne With a Novel Skin Care System Containing 1% Salicylic Acid, 10% Buffered Glycolic Acid and Botanical Ingredients
More informationDERMATOLOGY FOR THE INTERNIST. Emilie Chow, MD 8/2017
DERMATOLOGY FOR THE INTERNIST Emilie Chow, MD 8/2017 GOALS ALL SLIDES ARE FOCUSED ON CLINICAL CASES IN THE FORM OF QUESTIONS AND MKSAP COVERED TOPICS USING POLLEV.COM Reference for material is MKSAP 17
More informationCHANGING THE FACE OF ROSACEA MANAGEMENT
A SUPPLEMENT TO Skin & Allergy News CHANGING THE FACE OF ROSACEA MANAGEMENT Chair Henry H. Roenigk, Jr., MD Professor Emeritus Northwestern University Medical School Arizona Advanced Dermatology Scottsdale
More informationDoxycycline/Minocycline Step Therapy Criteria Program Summary
This criteria applies to Commercial, NetResults F series and Health Insurance Marketplace formularies. OBJECTIVE The intent of the Doxycycline/Minocycline Step Therapy (ST) program is to encourage the
More informationSAFE? ALL YOU NEED ONE LAB
Safety tests 1 Is your product SAFE? 2 Client orientation - Mainly In- vivo Tests - Clinical control - Volunteers: - 3000 volunteers database - Caucasian, negroid, asian - Several skin types - Fast recruitment
More informationSudden Appearance of Indurated Erythematous Plaques on a Man's Face
Touro College and University System Touro Scholar NYMC Student Publications Students 2016 Sudden Appearance of Indurated Erythematous Plaques on a Man's Face Adam Carter New York Medical College Karthikeyan
More informationAzelaic Acid 15% Gel: The Versatile Foundation of Combination Therapy in Mild to Moderate Rosacea in Various Patient Types COS DERM
Review Azelaic Acid 15% Gel: The Versatile Foundation of Combination Therapy in Mild to Moderate Rosacea in Various Patient Types Jeanine Downie, MD Rosacea is a common, chronic dermatologic condition
More informationTo order reprints or e-prints of JDD articles please contact JDD
June 2017 534 VOLUME 16 ISSUE 6 Copyright 2017 ORIGINAL ARTICLE Journal of Drugs in Dermatology The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Truncal Acne Vulgaris Lauren K. Hoffman
More informationAllergic versus Contact
Allergic versus Contact Dermatitis Julie Sterbank, DO Assistant Clinical Professor Allergy/Immunology MetroHealth Medical Center/Case Western Reserve University Disclosure I have no financial disclosures
More informationRadiotherapy to the Prostate. Information for patients
Radiotherapy to the Prostate Information for patients Northern Centre for Cancer Care Freeman Hospital Introduction Your oncologist has advised you to have a course of radiotherapy to your prostate as
More informationPapulopustular rosacea and rosacea-like demodicosis: two phenotypes of the same disease?
DOI: 10.1111/jdv.14885 JEADV ORIGINAL ARTICLE Papulopustular rosacea and rosacea-like demodicosis: two phenotypes of the same disease? F.M.N. Forton, 1, * V. De Maertelaer 2 1 Dermatology Clinic, Brussels,
More informationTop 10 Skin Problems
THE UK GUIDE Top 10 Skin Problems Learn how a Dermatologist can solve your frustrating challenges with skin, scalp, hair and nails Jennifer Crawley MBChB, BSc (Hons), MRCP (Derm) BAD British Association
More informationSwiss S1 guideline for the treatment of rosacea
DOI: 10.1111/jdv.14349 JEADV GUIDELINES Swiss S1 guideline for the treatment of rosacea F. Anzengruber, 1 J. Czernielewski, 2 C. Conrad, 2 L. Feldmeyer, 3 N. Yawalkar, 3 P. H ausermann, 4 A. Cozzio, 5
More informationRosacea is a common dermatologic disorder
Pediatric Dermatology A Phase 3 Randomized, Double-blind, Vehicle-Controlled Trial of Azelaic Acid Foam 15% in the Treatment of Papulopustular Rosacea Zoe Diana Draelos, MD; Boni E. Elewski, MD; Julie
More informationRadiotherapy to the Spine. Information for patients. Northern Centre for Cancer Care Freeman Hospital
Radiotherapy to the Spine Information for patients Northern Centre for Cancer Care Freeman Hospital Introduction Your oncologist has advised a course of radiotherapy to the spine as part of your cancer
More informationOCULAR SURFACE DISEASE SYNDROMES WAYNE ISAEFF, MD LOMA LINDA UNIVERSITY DEPARTMENT OF OPHTHALMOLOGY
OCULAR SURFACE DISEASE SYNDROMES WAYNE ISAEFF, MD LOMA LINDA UNIVERSITY DEPARTMENT OF OPHTHALMOLOGY SURFACE DISEASE DRY EYE DYSFUNCTIONAL TEARS SYND ALLERGIC DISORDERS MEIBOMIAN GLAND PROBLEMS OCULAR IMMUNE
More informationClinical Study Synopsis
Clinical Study Synopsis This Clinical Study Synopsis is provided for patients and healthcare professionals to increase the transparency of Bayer's clinical research. This document is not intended to replace
More informationCONTRAINDICATIONS None. (4)
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use FINACEA FOAM safely and effectively. See full prescribing information for FINACEA FOAM. FINACEA (azelaic
More informationACNE BOOT CAMP TOPICAL THERAPY BASICS
ACNE BOOT CAMP TOPICAL THERAPY BASICS Lawrence J Green, MD Associate Clinical Professor of Dermatology George Washington University School of Medicine Washington DC Relevant Disclosures Investigator -Allergan,
More informationOverview & pathophysiology of Dry Eye and the use of cyclosporine eye drops in dry eye...
Overview & pathophysiology of Dry Eye and the use of cyclosporine eye drops in dry eye... This Allergan sponsored session was held on July 24, 2005, Hotel Satya Ashoka, Jabalpur. The session was followed
More informationIndex. derm.theclinics.com. Note: Page numbers of article titles are in boldface type.
Note: Page numbers of article titles are in boldface type. A Abnormal wound healing Acne and cybereducation, 131 and Google, 129 131 and online dangers, 131, 132 reliable online resources on, 130 self-proclaimed
More informationBlepharitis. Information for patients Ophthalmology (Emergency Eye Centre) Large Print
Blepharitis Information for patients Ophthalmology (Emergency Eye Centre) Large Print page 2 of 12 Blepharitis is a condition where the rims of the eyelids become inflamed (red and swollen), which can
More information! Alcon! Carl Zeiss Meditec! Reichert! Thrombogenics! Zeavision! Kemin. ! CE Companies:
ROSACEA REVIEW Joseph J. Pizzimenti, OD, FAAO Associate Professor Nova Southeastern University pizzimen@nova.edu Financial Disclosure! Dr. Pizz has received honoraria from, participated in paid advisory
More informationKnow your Acne. Acne. Causes Of Acne. Published on: 7 Nov 2010
Published on: 7 Nov 2010 Know your Acne Acne All of us have glands that produce oil to keep our skin from becoming dry and flaky. However, sometimes, our oil glands overproduce! This is what commonly causes
More informationDaily Oxymetazoline Cream Demonstrates High and Sustained Efficacy in Patients With Persistent Erythema of Rosacea Through 52 Weeks of Treatment
Accepted Manuscript Daily Oxymetazoline Cream Demonstrates High and Sustained Efficacy in Patients With Persistent Erythema of Rosacea Through 52 Weeks of Treatment Michael H. Gold, MD, FAAD, Mark Lebwohl,
More informationDOSAGE AND ADMINISTRATION Apply a thin layer of FINACEA Gel twice daily to affected area(s).
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use FINACEA Gel safely and effectively. See full prescribing information for FINACEA Gel. FINACEA (azelaic
More informationThe skin is the largest organ of the human body. Functions: protection sensation maintain temperature vitamin synthesis
Dermatology The skin is the largest organ of the human body. Functions: protection sensation maintain temperature vitamin synthesis The image to the left shows an image of skin cells and the proteins which
More informationACNE UPDATE 2017 FACULTY DISCLOSURE ACNE UPDATE
ACNE UPDATE 2017 PATRICIA TREADWELL, M.D. PROFESSOR OF PEDIATRICS AND DERMATOLOGY IU SCHOOL OF MEDICINE FACULTY DISCLOSURE I have no relevant financial relationships with the manufacturer(s) of any commercial
More informationPrior Authorization Review Panel MCO Policy Submission
Prior Authorization Review Panel MCO Policy Submission A separate copy of this form must accompany each policy submitted for review. Policies submitted without this form will not be considered for review.
More informationPsoriasis: Causes, Symptoms, And Treatment
Psoriasis: Causes, Symptoms, And Treatment We all know that a healthy immune system is good. But, do you know that an overactive immune system can cause certain conditions like Psoriasis? Read on to find
More informationOcular Allergy. Phil Lieberman, MD
Ocular Allergy Phil Lieberman, MD Disclosure Consultant/Advisory Board: Genentech, Meda, Mylan, Teva Speaker: Genentech, Meda, Merck, Mylan, Teva Learning Objectives Upon completion of this session, participants
More informationAllergy Medications. Antihistamines. are very safe. Although usually taken as tablets, they may be prescribed as a liquid or syrup for young children
The treatments prescribed for allergy control the symptoms and reactions; they do not cure the condition. However, using treatments as prescribed can show a huge change in a patient s health, mood and
More informationRedness and Rosacea YOLANDA R. HELFRICH, M.D. ASSOCIATE PROFESSOR DEPARTMENT OF DERMATOLOGY
Redness and Rosacea YOLANDA R. HELFRICH, M.D. ASSOCIATE PROFESSOR DEPARTMENT OF DERMATOLOGY DISCLOSURE OF RELEVANT RELATIONSHIPS WITH INDUSTRY Yolanda Rosi Helfrich, MD F135: Redness and Rosacea DISCLOSURES
More informationOral Azithromycin Pulse Therapy and Daily Topical Benzoyl Peroxide in the Treatment of Acne Vulgaris: An Open Clinical Trial Study
Journal of Bangladesh College of Physicians and Surgeons Vol. 36, No. 1, January 218 Oral Azithromycin Pulse Therapy and Daily Topical Benzoyl Peroxide in the Treatment of Acne Vulgaris: An Open Clinical
More informationNEHSNORTH EASTERN HEALTH SPECIALISTS
COSMETIC DERMATOLOGY NEHSNORTH EASTERN HEALTH SPECIALISTS nehs.com.au CONSENT FORM VASCULAR Treatment with BBL & LASERS I, DOB:, of authorize of North Eastern Health Specialist to perform hair removal
More informationEczema. By:- Dr. Naif Al-Shahrani Salman bin Abdazziz University
Eczema By:- Dr. Naif Al-Shahrani Salman bin Abdazziz University Dermatitis= Eczema =Spongiosis Eczema Atopic Seborrheic Contact Allergic Irritant Nummular Asteatotic Stasis Neurodermatitis/Lichen Simplex
More informationreversing erythrotelangiectatic rosacea naturally the raw vegan plant based detoxification regeneration workbook for healing patients volume 2
DOWNLOAD OR READ : REVERSING ERYTHROTELANGIECTATIC ROSACEA NATURALLY THE RAW VEGAN PLANT BASED DETOXIFICATION REGENERATION WORKBOOK FOR HEALING PATIENTS VOLUME 2 PDF EBOOK EPUB MOBI Page 1 Page 2 healing
More informationRosacea Update: Rosacea pathogenesis. Rosacea genetics. Disclosures. Rosacea: Etiology? Th1/Th17 is activated in rosacea skin
Winter Clinical Big Island 20 min Rosacea Update: 2017 Diane M. Thiboutot, M.D. Professor of Dermatology The Pennsylvania State University College of Medicine Hershey, PA Disclosures Investigator or consultant
More informationBBLs BroadBand Light. Daryl Mossburg, RN BSN Clinical Specialist Sciton, Inc. All rights reserved.
BBLs BroadBand Light Daryl Mossburg, RN BSN Clinical Specialist 1 2009 Sciton, Inc. All rights reserved. BBL - BroadBand Light BBL module incorporated into JOULE BBLs Standalone System 2 2009 Sciton, Inc.
More informationDerm quiz. Go to this link: goo.gl/forms/kchrhmtzl3vfnlv52. bit.ly/2a8asoy. Scan the QR code with your phone
Dermatology quiz Derm quiz Go to this link: goo.gl/forms/kchrhmtzl3vfnlv52 OR bit.ly/2a8asoy OR Scan the QR code with your phone Contents Childhood rashes Pigmented lesions Sun damage Pityriasis References
More informationNonpharmacologic Treatment of Rosacea Corporate Medical Policy
Nonpharmacologic Treatment of Rosacea Corporate Medical Policy File Name: Nonpharmacologic Treatment of Rosacea. File Code: UM.SURG.11 Last Review: 01/2019 Next Review: 01/2020 Effective Date: 04/01/2019
More informationReference ID:
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use FINACEA Gel safely and effectively. See full prescribing information for FINACEA Gel. FINACEA (azelaic
More informationLung Pathway Group Afatinib in Non-Small Cell Lung Cancer (NSCLC)
Lung Pathway Group Afatinib in Non-Small Cell Lung Cancer (NSCLC) Indication: NICE TA310 First line treatment option in locally advanced or metastatic NSCLC Positive test for epidermal growth factor receptor
More informationThe Evaluation of Contact Sensitivity with Standard and Cosmetic Patch Test Series in Rosacea Patients
HK Erdogan, et al pissn 1013-9087ㆍeISSN 2005-3894 Ann Dermatol Vol. 30, No. 3, 2018 https://doi.org/10.5021/ad.2018.30.3.290 ORIGINAL ARTICLE The Evaluation of Contact Sensitivity with Standard and Cosmetic
More informationDermaPep A530. Multifunctional anti-inflammatory peptide for irritated and sensitive skin. Experience The Magic of Science
Experience The Magic of Science DermaPep A53 Multifunctional anti-inflammatory peptide for irritated and sensitive skin DermaP ep Experience the magic of science Anti-aging DermaPep A35 DermaPep A42 DermaPep
More informationRandomized, double-blind trial of 220 mg zinc sulfate twice daily in the treatment of rosacea
Clinical trial Randomized, double-blind trial of 220 mg zinc sulfate twice daily in the treatment of rosacea Joel T. M. Bamford 1, MD, Charles E. Gessert 2, MD, MPH, Irina V. Haller 2, PhD, MS, Kim Kruger
More informationCORNEAL CONDITIONS CORNEAL TRANSPLANTATION
GENERAL INFORMATION CORNEAL CONDITIONS CORNEAL TRANSPLANTATION WHAT ARE CORNEAL CONDITIONS? The cornea is the clear outer layer of the eye. Shaped like a dome, it helps to protect the eye from foreign
More informationClinical Study Synopsis for Public Disclosure
Clinical Study Synopsis for Public Disclosure These results are supplied for informational purposes only in the interest of scientific disclosure. The synopsis may include approved and non-approved uses,
More informationSHEPROS PIMPLE GEL. SHEPROS Sdn. Bhd. [An Alliance of SHEPROS International (USA) LLC.] Safety, Heath & Environment Product Solutions
SHEPROS Safety, Heath & Environment Product Solutions PIMPLE GEL SHEPROS Sdn. Bhd. [An Alliance of SHEPROS International (USA) LLC.] Pimples What are pimples? A pimple is a small pustule or papule. Pimples
More information