Lichen sclerosus is a chronic inflammatory

Size: px
Start display at page:

Download "Lichen sclerosus is a chronic inflammatory"

Transcription

1 DERMATOLOGY Lichen Sclerosus et Atrophicus in a Young Girl YS Marfatia*, SoNIA JAIN** Abstract Lichen sclerosus et atrophicus is a chronic inflammatory dermatosis that results in white plaques and epidermal atrophy. The condition has both genital and extragenital presentations. Here we describe the case of a 12-year-old girl who presented to us with white plaques over her genitals and no manifestation of extragenital disease. Keywords: Lichen sclerosus et atrophicus, lichen albus, white spot disease Lichen sclerosus is a chronic inflammatory dermatosis that most commonly affects the anogenital region and leads to intractable pruritus and soreness. The condition is more common in females 1 as in the present case also the patient is a young girl who presented with complaints of white plaques with itching over the genitals since her prepubertal years. The condition involves the risk of malignant transformation more so over the genital lesions but the precise incidence has not been defined. Pathophysiologically, the condition is associated with the presence of autoantibodies to glycoprotein extracellular matrix protein 1 (ECM-1). 2 Several risk factors have also been proposed including autoimmune diseases, infections and genetic predisposition. 3 There is evidence of its association with thyroid disease. 4 Figure 1. Photograph showing labial atrophy. CASE SUMMARY A 12-year-old young girl presented to us with depigmented patches over the genitals, which had an insidious onset and were gradually progressive over a period of one year (Fig. 1). She had moderate itching over the site and she had seen many doctors for her complaints but had no relief. On dermatological examination, labia majora showed atrophy along with depigmentation of the labia minora (Fig. 2). The *Professor and Head Dept. of Skin and VD, Baroda Medical College SSG Hospital, Raopura, Vadodara, Gujarat **Professor Dept. of Skin and VD MGIMS, Sewagram, Wardha, Maharashtra Address for correspondence Dr Sonia Jain A-14, Dhanvantri Nagar MGIMS, Sewagram, Wardha, Maharashtra Figure 2. Photograph showing depigmented patch over the labia. depigmented patches extended from the fourchette to the vestibule and she had no oral or cutaneous lesions elsewhere. There was no history of sexual abuse or any high-risk behavior and none of the family members Indian Journal of Clinical Practice, Vol. 24, No. 6, November

2

3

4 DERMATOLOGY abuse associated with a higher incidence of LSA in pediatric population. Besides, they also described the association of LSA with infection, autoimmunity and trauma. There has been a case on the records wherein Virdi and Kanwar reported the co-existence of localized cutaneous morphea with LSA and submucosal fibrosis in a middle-aged man in his late-thirties. 5 Another citation of a similar association between the aforesaid conditions has been mentioned by Prasad and Padmavathy et al, wherein they reported a case of a young male in his mid-twenties who presented with generalized morphea and LSA along with osteolytic bone changes. 6 However, our patient showed no signs of morphea or any other systemic disease. Figure 3. Histology showing homogenization of the collagen and inflammatory infiltrate in the dermis. had a similar clinical picture. She had no urinary or bowel complaints. We performed a labial biopsy from the depigmented patch after taking a written informed consent and the histopathological findings were consistent with Lichen sclerosus et atrophicus (LSA) showing homogenization of the collagen and inflammatory infiltrate in the dermis (Fig. 3). DISCUSSION Lichen sclerosus is also known as LSA, balanitis xerotica obliterans (BXO) in men, Csillag s disease, White spot disease, Lichen albus and Krauosis vulvae. LSA was first described in 1887 by Dr Hallopeau. A case series of 42 children (all females) suffering from LSA has been reported by Shirley A Warrington and Camille de San Lazaro where they found a high incidence of sexual REFERENCES 1. Tasker GL, Wojnarowska F. Lichen sclerosus. Clin Exp Dermatol 2003;28(2): Chan I, Oyama N, Neill SM, Wojnarowska F, Black MM, McGrath JA. Characterization of IgG autoantibodies to extracellular matrix protein 1 in lichen sclerosus. Clin Exp Dermatol 2004;29(5): Yesudian PD, Sugunendran H, Bates CM, O Mahony C. Lichen sclerosus. Int J STD AIDS 2005;16(7):465-73, test Birenbaum DL, Young RC. High prevalence of thyroid disease in patients with lichen sclerosus. J Reprod Med 2007;52(1): Virdi SK, Kanwar AJ. Generalized morphea, lichen sclerosis et atrophicus associated with oral submucosal fibrosis in an adult male. Indian J Dermatol Venereol Leprol 2009;75(1): Prasad PV, Padmavathy L, Sethurajan S, Kumar P, Rao L. Generalised morphoea with lichen sclerosus et atrophicus and unusual bone changes. Indian J Dermatol Venereol Leprol 1995;61(2): Cont d from page De La Blanchardiere A, Rozenberg F, Caumes E, Picard O, Lionnet F, Livartowski J, et al. Neurological complications of varicellazoster virus infection in adults with human immunodeficiency virus infection. Scand J Infect Dis 2000;32(3): Vafai A, Berger M. Zoster in patients infected with HIV: a review. Am J Med Sci 2001;321(6): Gershon AA, Mervish N, LaRussa P, Steinberg S, Lo SH, Hodes D, et al. Varicella-zoster virus infection in children with underlying human immunodeficiency virus infection. J Infect Dis 1997;176(6): Burke DG, Kalayjian RC, Vann VR, Madreperla SA, Shick HE, Leonard DG. Polymerase chain reaction detection and clinical significance of varicella-zoster virus in cerebrospinal fluid from human immunodeficiency virusinfected patients. J Infect Dis 1997;176(4): Friedman-Kien AE, Lafleur FL, Gendler E, Hennessey NP, Montagna R, Halbert S, et al. Herpes zoster: a possible early clinical sign for development of AIDS in high risk individual. J Am Acad Dermatol 1986;14(6): Blank LJ, Polydefkis MJ, Moore RD, Gebo KA. Herpes zoster among persons living with HIV in the current antiretroviral therapy era. J Acquir Immune Defic Syndr 2012;61(2): De Castro N, Carmagnat M, Kernéis S, Scieux C, Rabian C, Molina JM. Varicella-zoster virus-specific cell-mediated immune responses in HIV-infected adults. AIDS Res Hum Retroviruses 2011;27(10): Noonan L, Gunson T, Ellis-Pegler R, Thomas M, Briggs S. Short-course intravenous aciclovir treatment for cutaneous herpes zoster in patients with HIV infection. Int J STD AIDS 2012;23(5): Indian Journal of Clinical Practice, Vol. 24, No. 6, November 2013

5 EDGE India reprint/galvus/cvm/097/11/13

6 GASTROENTEROLOGY 536 Indian Journal of Clinical Practice, Vol. 24, No. 3, August 2013 EDGE India reprint/galvus/cvm/097/11/13

Rameshwar Gutte and Uday Khopkar

Rameshwar Gutte and Uday Khopkar Extragenital unilateral lichen sclerosus et atrophicus in a child: a case report Rameshwar Gutte and Uday Khopkar Department of Dermatolgy, Seth GSMC and KEM Hospital, Parel, Mumbai-400012, India Egyptian

More information

The use of CO2 laser for patients with Lichen sclerosus

The use of CO2 laser for patients with Lichen sclerosus The use of CO2 laser for patients with Lichen sclerosus Dr. Christina Kuhler-Obbarius, Elisabeth Kunkel, Dr. Matthias Theden-Schow, Hamburg, Germany Our clinical center located in Hamburg includes eight

More information

Lichen sclerosus (LS) is an uncommon inflammatory. Constipation as a Feature of Anogenital Lichen Sclerosus in Children

Lichen sclerosus (LS) is an uncommon inflammatory. Constipation as a Feature of Anogenital Lichen Sclerosus in Children Mandi L. Maronn, MD*, and Nancy B. Esterly, MD ABSTRACT. Objective. To call attention to constipation as a frequent sign of lichen sclerosus (LS) in girls. Methods. A focused questionnaire was sent to

More information

Disorders of the vulva

Disorders of the vulva Vulval lesions Disorders of the vulva Terminology standardised by the International Society for the Study of Vulvovaginal Disease(ISSVD) Classification 1.Nonneoplastic epithelial disorders of vulva Lichen

More information

A Histopathologic Study of Connective Tissue Diseases of Skin

A Histopathologic Study of Connective Tissue Diseases of Skin Original Article Indian Journal of Pathology: Research and Practice 393 Volume 6 Number 2, April - June 2017 (Part 2) DOI: http://dx.doi.org/10.21088/ijprp.2278.148x.6217.9 A Histopathologic Study of Connective

More information

Morphea-A Case Report

Morphea-A Case Report IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-issn: 2279-0853, p-issn: 2279-0861.Volume 15, Issue 2 Ver. VII (Feb. 2016), PP 09-13 www.iosrjournals.org Morphea-A Case Report Gurjit Singh 1,

More information

Non venereal benign dermatoses of vulva in sexually active women: a clinical study

Non venereal benign dermatoses of vulva in sexually active women: a clinical study International Journal of Research in Dermatology Singh G et al. Int J Res Dermatol. 2016 Jun;2(2):25-29 http://www.ijord.com Research Article DOI: http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20162419

More information

Lichen sclerosus. Lichen planus

Lichen sclerosus. Lichen planus Lichen sclerosus Lichen planus Dr Fiona Lewis, Consultant Dermatologist, Heatherwood and Wexham Park NHS Foundation Trust & St John s Institute of Dermatology, GSTT Outline Typical features of lichen sclerosus

More information

JMSCR Vol 05 Issue 10 Page October 2017

JMSCR Vol 05 Issue 10 Page October 2017 www.jmscr.igmpublication.org Impact Factor 5.84 Index Copernicus Value: 71.58 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi.org/10.18535/jmscr/v5i10.125 Histomorphological Study of Lichen Planus

More information

Lichen sclerosus et atrophicus and sexual abuse

Lichen sclerosus et atrophicus and sexual abuse 512 Archives ofdisease in Childhood 1996;75:512-516 Department of Child Health, University of Newcastle upon Tyne, Lindisfarne Centre, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne

More information

Non-Venereal Female Genital Dermatoses A Clinical Study

Non-Venereal Female Genital Dermatoses A Clinical Study JMSCR Volume 2 Issue 11 Page 2864-2873 November-2014 2864-2902 November-2014 2014 www.jmscr.igmpublication.org Impact Factor 3.79 ISSN (e)-2347-176x ABSTRACT Non-Venereal Female Genital Dermatoses A Clinical

More information

Epidemiological study of Lichen Planus

Epidemiological study of Lichen Planus Year: 2014; Volume: 1; Issue: 1 Article ID: MD14 20; Pages: 1-9 BioMed Research The Open Access Publisher BMR Medicine Research Article Epidemiological study of Lichen Planus Shankar Gouda Ireddy 1 and

More information

Treatment of Bowenoid and Basaloid Vulvar Intraepithelial Neoplasia 2/3 with Imiquimod 5% Cream DO NOT DUPLICATE

Treatment of Bowenoid and Basaloid Vulvar Intraepithelial Neoplasia 2/3 with Imiquimod 5% Cream DO NOT DUPLICATE The Journal of Reproductive Medicine Treatment of Bowenoid and Basaloid Vulvar Intraepithelial Neoplasia 2/3 with Imiquimod 5% Cream Claudia Marchitelli, M.D., Graciela Secco, M.D., Myriam Perrotta, M.D.,

More information

Vaginal involvement in genital erosive lichen planus

Vaginal involvement in genital erosive lichen planus Acta Obstetricia et Gynecologica. 2010; 89: 966 970 SHORT REPORT Vaginal involvement in genital erosive lichen planus ANNE LISE ORDING HELGESEN 1,2,3, PETTER GJERSVIK 3,4, PETER JEBSEN 5, ROLF KIRSCHNER

More information

Department of Dermatology, Christian Medical College and Hospital, Ludhiana, Punjab, India.

Department of Dermatology, Christian Medical College and Hospital, Ludhiana, Punjab, India. Bullous pemphigoid mimicking granulomatous inflammation Abhilasha Williams, Emy Abi Thomas. Department of Dermatology, Christian Medical College and Hospital, Ludhiana, Punjab, India. Egyptian Dermatology

More information

Epidemiological study, clinical spectrum and associations of childhood vitiligo in a tertiary care centre

Epidemiological study, clinical spectrum and associations of childhood vitiligo in a tertiary care centre International Journal of Research in Dermatology Murugaiyan R. Int J Res Dermatol. 2016 Dec;2(4):86-90 http://www.ijord.com Original Research Article DOI: http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20163976

More information

Study. Skin changes in internal malignancy

Study. Skin changes in internal malignancy Study Skin changes in internal malignancy R. Rajagopal, P. N. Arora $, C. V. Ramasastry*, P. K. Kar # Dept of Dermatology, 5 Air Force Hospital, C/o 99 APO, $ Former Prof & Head, Dept. of Dermatology,

More information

WHITE PAPER SmartXide 2 V 2 LR. MonaLisa Touch Dual Probe Therapy for the Treatment of Lichen Sclerosus and Vaginal Atrophy

WHITE PAPER SmartXide 2 V 2 LR. MonaLisa Touch Dual Probe Therapy for the Treatment of Lichen Sclerosus and Vaginal Atrophy WHITE PAPER SmartXide 2 V 2 LR MonaLisa Touch Dual Probe Therapy for the Treatment of Lichen Sclerosus and Vaginal Atrophy DEKA White Paper SMARTXIDE 2 V 2 LR November 2015 MonaLisa Touch Dual Probe Therapy

More information

Key words: genotyping/hla-dq/hla-dr/lichen sclerosus/susceptibility J Invest Dermatol 125: , 2005

Key words: genotyping/hla-dq/hla-dr/lichen sclerosus/susceptibility J Invest Dermatol 125: , 2005 The Association Between HLA DR, DQ Antigens, and Vulval Lichen Sclerosus in the UK: HLA DRB1 12 and its Associated DRB1 12/DQB1 0301/04/09/010 Haplotype Confers Susceptibility to Vulval Lichen Sclerosus,

More information

The Great Imitator Revealed: Syphilis

The Great Imitator Revealed: Syphilis The Great Imitator Revealed: Syphilis Jeffrey D. Klausner, MD, MPH Professor of Medicine and Public Health University of California Los Angeles David Geffen School of Medicine Los Angeles, California Learning

More information

Sexual Abuse. Dr Burke Baird

Sexual Abuse. Dr Burke Baird Sexual Abuse Dr Burke Baird Unlike physical abuse, where you are typically faced with a suspicious injury and you go looking for an explanation, with sexual abuse, you usually start with a verbal disclosure

More information

Clinically Microscopically Pathogenesis: autoimmune not lifetime

Clinically Microscopically Pathogenesis: autoimmune not lifetime Vulvar Diseases: Can be divided to non-neoplastic and neoplastic diseases. The neoplastic diseases are much less common. Of those, squamous cell carcinoma is the most common. most common in postmenopausal

More information

Citation The Journal of dermatology, 37(1), available at

Citation The Journal of dermatology, 37(1), available at NAOSITE: Nagasaki University's Ac Title Author(s) Case of localized scleroderma assoc Muroi, Eiji; Ogawa, Fumihide; Yamao Sato, Shinichi Citation The Journal of dermatology, 37(1), Issue Date 2010-01 URL

More information

Diagnosis? 2/17/2018. Case year old female. F045 Dermpath Case Challenge

Diagnosis? 2/17/2018. Case year old female. F045 Dermpath Case Challenge Case 1 75 year old female F045 Dermpath Case Challenge Tammie Ferringer, MD Depts of Dermatology and Pathology Danville, PA tferringer@geisinger.edu 1 year history of undiagnosed joint pain and 6 month

More information

Degos Disease: A Case Report and Review of Literature

Degos Disease: A Case Report and Review of Literature Degos Disease: A Case Report and Review of Literature Monira waked Egyptian Dermatology Online Journal 4 (1): 5, June 2008 Al Houd Al Marsod Hospital Submitted for publication: May 25 th, 2008 Accepted

More information

MUCOCUTANEOUS MANIFESTATIONS OF HIV/AIDS IN ADOLESCENTS

MUCOCUTANEOUS MANIFESTATIONS OF HIV/AIDS IN ADOLESCENTS MUCOCUTANEOUS MANIFESTATIONS OF HIV/AIDS IN ADOLESCENTS Dr. Y.S.MARFATIA Prof. and Head, Dept. Skin & V.D. Medical college, Vadodara LET US CREATE BRILLIANCE TOGETHER MEDICAL COLLEGE, VADODARA Editor in

More information

CUTANEOUS PARANEOPLASTIC MANIFESTATION (MORPHEA, LICHEN SCLEROSUS) TWO CASE REPORTS

CUTANEOUS PARANEOPLASTIC MANIFESTATION (MORPHEA, LICHEN SCLEROSUS) TWO CASE REPORTS 8 ED R 07 7/ DO: 0.55/acm-07-0004 UEOUS PREOPLS FESO (ORPHE, LHE SLEROSUS) WO SE REPORS PPPOV, PE J, KOZROV, DOV K. omenius University Jessenius Faculty of edicine and University Hospital, Department of

More information

Update on Medical Aspects. Mission Children s Hospital. Cindy Brown, MD. Asheville, NC. Child sexual abuse

Update on Medical Aspects. Mission Children s Hospital. Cindy Brown, MD. Asheville, NC. Child sexual abuse Child sexual abuse Update on Medical Aspects Cindy Brown, MD Mission Children s Hospital Asheville, NC Objectives Genital examination Techniques Findings Examiners Sexually transmitted infections THE GENITAL

More information

A retrospective study of the pattern of sexually transmitted diseases during a ten-year period METHODS

A retrospective study of the pattern of sexually transmitted diseases during a ten-year period METHODS Study A retrospective study of the pattern of sexually transmitted diseases during a ten-year period Beena Narayanan Department of Dermatology and Venereology, Medical College Hospital, Kottayam, Kerala,

More information

Vulval dermatoses. Dr Fiona Lewis, Consultant Dermatologist St John s Institute of Dermatology, London & Heatherwood & Wexham Park Hospital, Slough

Vulval dermatoses. Dr Fiona Lewis, Consultant Dermatologist St John s Institute of Dermatology, London & Heatherwood & Wexham Park Hospital, Slough Vulval dermatoses Dr Fiona Lewis, Consultant Dermatologist St John s Institute of Dermatology, London & Heatherwood & Wexham Park Hospital, Slough Pigmentation Vulvodynia Ulcers Genetic Pruritus VULVAL

More information

British Association of Dermatologists Undergraduate Award Essay Prize Who should look after genital skin disease in the 21 st century?

British Association of Dermatologists Undergraduate Award Essay Prize Who should look after genital skin disease in the 21 st century? Who should look after genital skin disease in the 21 st century? Sethuparvathy Jayakumar, 4 th year medical student, King s College London GKT School of Medical Education Genital skin disease is a broad

More information

IP10/CXCL10 CXCR3 Interaction: a Potential Self-recruiting Mechanism for Cytotoxic Lymphocytes in Lichen Sclerosus et Atrophicus

IP10/CXCL10 CXCR3 Interaction: a Potential Self-recruiting Mechanism for Cytotoxic Lymphocytes in Lichen Sclerosus et Atrophicus Acta Derm Venereol 2007; 87: 112 117 INVESTIGATIVE REPORT IP10/CXCL10 CXCR3 Interaction: a Potential Self-recruiting Mechanism for Cytotoxic Lymphocytes in Lichen Sclerosus et Atrophicus Joerg Wenzel,

More information

Correlation of clinical and histopathological classification of Leprosy in post elimination era

Correlation of clinical and histopathological classification of Leprosy in post elimination era Indian J Lepr 2012, 84 : 271-275 Hind Kusht Nivaran Sangh, New Delhi http://www.ijl.org.in Original Article Correlation of clinical and histopathological classification of Leprosy in post elimination era

More information

Egyptian Dermatology Online Journal Vol. 5 No 2:5, December 2009

Egyptian Dermatology Online Journal Vol. 5 No 2:5, December 2009 Cutaneous Manifestations of Diabetes mellitus: A Hospital Based Study in Kashmir, India Mashkoor Ahmed Wani, MD 1 *; Iffat Hassan, MD 2 *; Mohd Hayat Bhat, DM 3 and Qazi Masood Ahmed, MD 4 * Egyptian Dermatology

More information

MUHS /03/2079 Additional Qualification certificate number -0214/2010 Dated -20/01/2010

MUHS /03/2079 Additional Qualification certificate number -0214/2010 Dated -20/01/2010 Name of the Teacher: DR. RESHAM JAYVANT VASANI Name of the Department: DERMATOLOGY Current post held: ASSISTANT PROFESSOR Date on which this format was filled (dd/mm/yyyy): 15/03/2017 Details of educational

More information

Summary. Accepted for publication 18 May Key words genital lichen planus, oral lichen planus, vulval lichen planus

Summary. Accepted for publication 18 May Key words genital lichen planus, oral lichen planus, vulval lichen planus CLINICAL AND LABORATORY INVESTIGATIONS DOI 10.1111/j.1365-2133.2006.07480.x Prevalence of vulval lichen planus in a cohort of women with oral lichen planus: an interdisciplinary study P. Belfiore, O. Di

More information

Clinical Scoring System to Detect Malignant and Premalignant Vulval Lesions

Clinical Scoring System to Detect Malignant and Premalignant Vulval Lesions The Journal of Obstetrics and Gynecology of India (January February 2014) 64(1):41 46 DOI 10.1007/s13224-013-0458-3 ORIGINAL ARTICLE Clinical Scoring System to Detect Malignant and Premalignant Vulval

More information

It has been estimated that 90% of individuals

It has been estimated that 90% of individuals Famciclovir for Cutaneous Herpesvirus Infections: An Update and Review of New Single-Day Dosing Indications Manju Chacko, MD; Jeffrey M. Weinberg, MD Infections with herpes simplex virus (HSV) types 1

More information

SAQ SELF ASSESSMENT QUIZ. Unilateral depigmented lesions on the right arm. Azmy Abdullatif, MD, 1 Bayoumi Essa, MD 2

SAQ SELF ASSESSMENT QUIZ. Unilateral depigmented lesions on the right arm. Azmy Abdullatif, MD, 1 Bayoumi Essa, MD 2 SELF ASSESSMENT QUIZ Unilateral depigmented lesions on the right arm Azmy Abdullatif, MD, 1 Bayoumi Essa, MD 2 1 Prof. of Dermatology, Al Azhar University, Cairo, Egypt 2 Consultant Dermatologist, Farwaniya

More information

Vitiligo: How many types?

Vitiligo: How many types? Vitiligo Evidence Based Update, Holywell Park, Loughborough, 23 May 2013 Vitiligo: How many types? Alain Taïeb Dept of Dermatology and Pediatric Dermatology National Reference Centre for Rare Skin Disorders,

More information

ISPUB.COM. A Case of Actinic Lichen Planus. K Choi, H Kim, H Kim, Y Park INTRODUCTION CASE REPORT

ISPUB.COM. A Case of Actinic Lichen Planus. K Choi, H Kim, H Kim, Y Park INTRODUCTION CASE REPORT ISPUB.COM The Internet Journal of Dermatology Volume 8 Number K Choi, H Kim, H Kim, Y Park Citation K Choi, H Kim, H Kim, Y Park.. The Internet Journal of Dermatology. 2009 Volume 8 Number. Abstract The

More information

Clearance in vulvar lichen sclerosus: a realistic treatment endpoint or a chimera?

Clearance in vulvar lichen sclerosus: a realistic treatment endpoint or a chimera? DOI: 10.1111/jdv.14516 JEADV SHORT REPORT Clearance in vulvar lichen sclerosus: a realistic treatment endpoint or a chimera? A. Borghi,* A. Virgili, S. Minghetti, G. Toni, M. Corazza Dipartimento di Scienze

More information

Sexual Assault: The Medical Evaluation & Forensic Evidence Collection

Sexual Assault: The Medical Evaluation & Forensic Evidence Collection Sexual Assault: The Medical Evaluation & Forensic Evidence Collection North American Society of Pediatric and Adolescent Gynecology Annual Conference and Research Meeting April 7, 2016 Casey Weary, RN,

More information

Uncommon clinical presentations of leprosy: apropos of three cases

Uncommon clinical presentations of leprosy: apropos of three cases Lepr Rev (2016) 87, 246 251 CASE REPORT Uncommon clinical presentations of leprosy: apropos of three cases RASHMI JINDAL* & NADIA SHIRAZI** *Department of Dermatology, Venereology & Leprosy, Himalayan

More information

Patient Satisfaction of Surgical Treatment of Clitoral Phimosis and Labial Adhesions Caused by Lichen Sclerosus

Patient Satisfaction of Surgical Treatment of Clitoral Phimosis and Labial Adhesions Caused by Lichen Sclerosus ORIGINAL RESEARCH WOMEN S SEXUAL HEALTH Patient Satisfaction of Surgical Treatment of Clitoral Phimosis and Labial Adhesions Caused by Lichen Sclerosus Anne N. Flynn, MD,* Michelle King, MSc, Mollie Rieff,

More information

OCCG SERVICE SPECIFICATION (2017/18)

OCCG SERVICE SPECIFICATION (2017/18) OCCG SERVICE SPECIFICATION (2017/18) Primary Care Service for Skin Cancers: Dermatology Shared Care Monitoring for Melanoma, Lichen Sclerosus and Squamos Cell Carcinoma 1. Background For patients who have

More information

What caused this refractory pruritic eruption? Patient Presentation

What caused this refractory pruritic eruption? Patient Presentation What caused this refractory pruritic eruption? Patient Presentation A 67 year-old female presented with greater than 3 years of refractory and debilitating intermittent bouts of recurrent pruritus on the

More information

Inflammatory Dermatoses of the Vulva for the General/Gyn Pathologist with emphasis in the lichenoid pattern

Inflammatory Dermatoses of the Vulva for the General/Gyn Pathologist with emphasis in the lichenoid pattern Inflammatory Dermatoses of the Vulva for the General/Gyn Pathologist with emphasis in the lichenoid pattern By Konstantinos Linos MD, FCAP, FASDP Bone, Soft Tissue and Dermatopathology Assistant Professor

More information

Psoriasis Penis - A Two Case Report

Psoriasis Penis - A Two Case Report Article ID: WMC003176 ISSN 2046-1690 Psoriasis Penis - A Two Case Report Corresponding Author: Dr. Ilko Bakardzhiev, MD, PhD, Medical College, Medical University of Varna, 9000 - Bulgaria Submitting Author:

More information

4/28/11 OBJECTIVES CASE. Solving a Mystery of Child Sexual Abuse: The Roles of the Clinician and CPS

4/28/11 OBJECTIVES CASE. Solving a Mystery of Child Sexual Abuse: The Roles of the Clinician and CPS Solving a Mystery of Child Sexual Abuse: The Roles of the Clinician and CPS ANN S. BOTASH, MD DIRECTOR, CARE PROFESSOR OF PEDIATRICS OBJECTIVES Explain why all children suspected of being sexually abused

More information

S016: Systemic Infections No conflicts for this talk

S016: Systemic Infections No conflicts for this talk Adventures in Syphilis Conflict of Interest Disclosure S016: Systemic Infections No conflicts for this talk TED ROSEN, MD PROFESSOR OF DERMATOLOGY BAYLOR COLLEGE OF MEDICINE HOUSTON, TEXAS Objectives Recognize

More information

A giant skin Tag over labium majus: An unusual location of skin tag

A giant skin Tag over labium majus: An unusual location of skin tag A giant skin Tag over labium majus: An unusual location of skin tag Garima Gupta 1, Ruchi Sinha 2, Sulekha Pandey 3, L. K. Pandey 3 Department of Obstetrics and Gynecology, Institute of Medical Sciences,

More information

Low-fluence Q-switched neodymium-doped yttrium aluminum garnet (1064nm) laser for the treatment of facial melasma in local population

Low-fluence Q-switched neodymium-doped yttrium aluminum garnet (1064nm) laser for the treatment of facial melasma in local population Original Article Low-fluence Q-switched neodymium-doped yttrium aluminum garnet (1064nm) laser for the treatment of facial melasma in local population Tahir Kamal, Usma Iftikhar* Department of Dermatology,

More information

A Clinical Study on 100 Cases of Herpes Zoster in a Tertiary Care Hospital

A Clinical Study on 100 Cases of Herpes Zoster in a Tertiary Care Hospital Original Article Print ISSN: 2321-6379 Online ISSN: 2321-595X DOI: 10.17354/ijss/2017/571 A Clinical Study on 100 Cases of Herpes Zoster in a Tertiary Care Hospital C Chandrakala 1, G K Tharini 2 1 Assistant

More information

Diseases of the vulva

Diseases of the vulva Diseases of the vulva 1. Bartholin Cyst - Infection of the Bartholin gland produces an acute inflammation within the gland (adenitis) and may result in an abscess. Bartholin duct cysts - Are relatively

More information

Introduction. Results. Discussion. Histopathologic and immunohistochemical findings. Results. conclusions,

Introduction. Results. Discussion. Histopathologic and immunohistochemical findings. Results. conclusions, 1/5 2/5 Carcinoma distinctive carcinoma. form erysipeloides (CE), metastasis. which clinically Itfrom has resembles been termed erysipelas, is an uncommon, but may extend It164 toclassically back, presents

More information

Lichen sclerosus. Information for patients Gynaecology

Lichen sclerosus. Information for patients Gynaecology Lichen sclerosus Information for patients Gynaecology page 2 of 8 What is lichen sclerosus? Lichen sclerosus is a skin condition that most often affects the vulva (the outer folds of skin around your vagina).

More information

Study of early diagnosis of various vesiculobullous lesions of the skin using histopathology

Study of early diagnosis of various vesiculobullous lesions of the skin using histopathology Original article: Study of early of various vesiculobullous lesions of the skin using histopathology Dr Sachin Parhe* Department of Pathology, DVVPF s Medical College & Hospital, Ahmednagar -414111. Corresponding

More information

A study of cutaneous manifestations associated with diabetes mellitus

A study of cutaneous manifestations associated with diabetes mellitus International Journal of Advances in Medicine Kadam MN et al. Int J Adv Med. 2016 May;3(2):296-303 http://www.ijmedicine.com pissn 2349-3925 eissn 2349-3933 Research Article DOI: http://dx.doi.org/10.18203/2349-3933.ijam20161079

More information

Meet the ISSVD. President ISSVD. Jacob Bornstein, MD

Meet the ISSVD. President ISSVD. Jacob Bornstein, MD Meet the ISSVD Jacob Bornstein, MD President ISSVD Chairman, Department of Obstetrics and Gynecology Western Galilee Hospital Bar-Ilan University Faculty of Medicine Nahariya, Israel ISSVD Symposium: The

More information

The Physical Signs of Child Sexual Abuse: an evidence-based review and guidance for best practice (2008) Interim statement Issued July 2011

The Physical Signs of Child Sexual Abuse: an evidence-based review and guidance for best practice (2008) Interim statement Issued July 2011 Royal College of Paediatrics and Child Health In collaboration with: The Royal College of Physicians of London, and its Faculty of Forensic and Legal Medicine The Physical Signs of Child Sexual Abuse:

More information

What will we discuss today?

What will we discuss today? Autoimmune diseases What will we discuss today? Introduction to autoimmune diseases Some examples Introduction to autoimmune diseases Chronic Sometimes relapsing Progressive damage Epitope spreading more

More information

Office Gynecology for the PCP

Office Gynecology for the PCP Office Gynecology for the PCP Hatim Omar, MD Professor, Pediatrics, Obstetrics/Gynecology Chief, Division of Adolescent Medicine KY CLINIC, Rm. L412, University of Kentucky Lexington, KY 40536-0284 Tel.

More information

Postmenopausal Vulvar Pruritus - Colposcopic Diagnosis and Treatment

Postmenopausal Vulvar Pruritus - Colposcopic Diagnosis and Treatment Postmenopausal Vulvar Pruritus - Colposcopic Diagnosis and Treatment Pages with reference to book, From 315 To 317 A Bilge Sener, Neslihan C. Seckin, Oya Gokmen ( Departments of Menopause, Dr. Z.T.B. Women

More information

Clinical Manifestations of HIV

Clinical Manifestations of HIV HIV Symptoms Diane Havlir, MD Professor of Medicine and Chief, HIV/AIDS Division University of California, San Francisco (UCSF) WorldMedSchool; July 2, 2013 1 Clinical Manifestations of HIV! Result from

More information

An epidemiological study of association of different dermatological and venereological manifestations with HIV

An epidemiological study of association of different dermatological and venereological manifestations with HIV International Journal of Research in Dermatology http://www.ijord.com Original Research Article DOI: http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20183164 An epidemiological study of association

More information

REGISTRY OF SEVERE CUTANEOUS ADVERSE REACTIONS TO DRUGS AND COLLECTION OF BIOLOGICAL SAMPLES. R e g i S C A R PATIENT'S DATA. Age country of birth

REGISTRY OF SEVERE CUTANEOUS ADVERSE REACTIONS TO DRUGS AND COLLECTION OF BIOLOGICAL SAMPLES. R e g i S C A R PATIENT'S DATA. Age country of birth REGISTRY OF SEVERE CUTANEOUS ADVERSE REACTIONS TO DRUGS AND COLLECTION OF BIOLOGICAL SAMPLES R e g i S C A R PATIENT'S DATA Initials of the patient date of birth Age country of birth Gender male female

More information

Megha M. Tollefson, MD Associate Professor of Dermatology and Pediatrics, Mayo Clinic Pediatric Morphea March 1, MFMER

Megha M. Tollefson, MD Associate Professor of Dermatology and Pediatrics, Mayo Clinic Pediatric Morphea March 1, MFMER Megha M. Tollefson, MD Associate Professor of Dermatology and Pediatrics, Mayo Clinic Pediatric Morphea March 1, 2019 2015 MFMER 3513105-1 Disclosures None 2015 MFMER 3513105-2 Topics to cover Classification

More information

MALE GENITAL (PENIS) LICHEN SCLEROSUS

MALE GENITAL (PENIS) LICHEN SCLEROSUS MALE GENITAL (PENIS) LICHEN SCLEROSUS What are the aims of this leaflet? This leaflet has been written to help you understand more about male genital lichen sclerosus (also known as balanitis xerotica

More information

Glistening, Skin-Colored Nodule

Glistening, Skin-Colored Nodule To Print: Click your browser's PRINT button. NOTE: To view the article with Web enhancements, go to: http://www.medscape.com/viewarticle/436334 Medscape Dermatology Clinic Glistening, Skin-Colored Nodule

More information

STUDY. Circumcision and Genital Dermatoses

STUDY. Circumcision and Genital Dermatoses STUDY Circumcision and Genital Dermatoses Eleanor Mallon, MRCP; David Hawkins, FRCP; Michael Dinneen, FRCS; Nicholas Francis, FRCPath; Louise Fearfield, MRCP; Roger Newson, DPhil; Christopher Bunker, FRCP

More information

Lichen sclerosus (LS) is a chronic disease and spontaneous. ActaDV ActaDV. Clinical Features, Complications and Autoimmunity in Male Lichen Sclerosus

Lichen sclerosus (LS) is a chronic disease and spontaneous. ActaDV ActaDV. Clinical Features, Complications and Autoimmunity in Male Lichen Sclerosus CLINICAL REPORT 365 Clinical Features, Complications and Autoimmunity in Male Lichen Sclerosus Despina KANTERE 1, Gunilla ALVERGREN 2, Martin GILLSTEDT 1, Fani PUJOL-CALDERÓN 3 and Petra TUNBÄCK 1 1 Department

More information

Skin Pathway Group Alemtuzumab in Cutaneous Lymphoma

Skin Pathway Group Alemtuzumab in Cutaneous Lymphoma Skin Pathway Group Alemtuzumab in Cutaneous Lymphoma Indication: Treatment of patients with Cutaneous Lymphoma (Unlicensed use) Disease control prior to Reduced Intensity Conditioning Stem Cell Transplant

More information

ANTIBODIES TO HERPES-SIMPLEX VIRUS IN THE CEREBROSPINAL FLUID OF PATIENTS WITH HER- PETIC ENCEPHALITIS

ANTIBODIES TO HERPES-SIMPLEX VIRUS IN THE CEREBROSPINAL FLUID OF PATIENTS WITH HER- PETIC ENCEPHALITIS ANTIBODIES TO HERPES-SIMPLEX VIRUS IN THE CEREBROSPINAL FLUID OF PATIENTS WITH HER- PETIC ENCEPHALITIS F. 0. MACCALLUM, I. J. CHINN AND J. V. T. GOSTLMG Virology Laboratory, Radclife Infirmary, Oxford

More information

Pearls from the Mayo Clinic

Pearls from the Mayo Clinic Pearls from the Mayo Clinic Lawrence E. Gibson, MD Professor of Dermatology and Laboratory Medicine and Pathology Mayo Clinic College of Medicine Rochester, MN Tattoo infections Tattoos very common (>24%

More information

Medical Findings in Child Sexual Abuse

Medical Findings in Child Sexual Abuse Medical Findings in Child Sexual Abuse Debra Esernio Jenssen, MD, FAAP Medical Director UF Child Protection Team Kori Stephens MPH Kori Stephens, MPH Medical Academy Coordinator Kori.stephens@childrensmn.org

More information

Giant Acrochordon of Vulva

Giant Acrochordon of Vulva Giant Madhusudan Dey, Reema Kumar, Raghu Sriram Department of Obstetric and Gynecology, Armed Forces Medical College, Pune, India Abstract Giant acrochordon or fibroepithelial stromal polyps usually occur

More information

Alemtuzumab in Cutaneous Lymphoma

Alemtuzumab in Cutaneous Lymphoma Alemtuzumab in Cutaneous Lymphoma Indication: Treatment of patients with Cutaneous Lymphoma (Unlicensed use) 1. Disease control prior to Reduced Intensity Conditioning Stem Cell Transplant 2. Palliative

More information

Human Immunodeficiency Virus. Acquired Immune Deficiency Syndrome AIDS

Human Immunodeficiency Virus. Acquired Immune Deficiency Syndrome AIDS Human Immunodeficiency Virus Acquired Immune Deficiency Syndrome AIDS Sudden outbreak in USA of opportunistic infections and cancers in young men in 1981 Pneumocystis carinii pneumonia (PCP), Kaposi s

More information

Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosus

Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosus pissn: 2288-6478, eissn: 2288-6761 https://doi.org/10.6118/jmm.2017.23.1.63 Case Report Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosus Seok Hwan Kim 1,

More information

ARTICLE. Children With Anogenital Symptoms and Signs Referred for Sexual Abuse Evaluations

ARTICLE. Children With Anogenital Symptoms and Signs Referred for Sexual Abuse Evaluations ARTICLE Children With Anogenital Symptoms and Signs Referred for Sexual Abuse Evaluations Nancy D. Kellogg, MD; Juan M. Parra, MD, MPH; Shirley Menard, RN, PhD, CPNP Objective: To determine whether children

More information

Mucocutaneous Manifestations In Hiv Patients In A Tertiary Care Centre

Mucocutaneous Manifestations In Hiv Patients In A Tertiary Care Centre IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-issn: 2279-0853, p-issn: 2279-0861.Volume 16, Issue 7 Ver. V (July. 2017), PP 58-64 www.iosrjournals.org Mucocutaneous Manifestations In Hiv Patients

More information

Clinicopathologic Self-Assessment

Clinicopathologic Self-Assessment Clinicopathologic Self-Assessment Handout Symposium (S003), July 27 th 2017 Maija Kiuru MD PhD Assistant Professor, Departments of Dermatology & Pathology University of California Davis CASE 1: History

More information

Lichen Sclerosus and Isolated Bulbar Urethral Stricture Disease

Lichen Sclerosus and Isolated Bulbar Urethral Stricture Disease Lichen Sclerosus and Isolated Bulbar Urethral Stricture Disease Joceline S. Liu,* Kelly Walker, Daniel Stein, Sanjiv Prabhu, Matthias D. Hofer, Justin Han, Ximing J. Yang and Chris M. Gonzalez Departments

More information

Journal of Pediatric Sciences

Journal of Pediatric Sciences Journal of Pediatric Sciences Progressive facial hemiatrophy with contralateral maxillary mucocele Mohd Ashraf, Sheikh Javeed Sultan, Javed Ahmad Journal of Pediatric Sciences 2010;2:e11 How to cite this

More information

11/1/18. Age and Vulvar Pathology ANATOMY. Prepuce Clitoris Vestibule Hart line. Labia. minora. Labia. majora. Fourchette.

11/1/18. Age and Vulvar Pathology ANATOMY. Prepuce Clitoris Vestibule Hart line. Labia. minora. Labia. majora. Fourchette. Age and Vulvar Pathology Maria Angelica Selim, MD Professor of Pathology and Dermatology Director Dermatopathology Unit Duke University Medical Center Labia minora Labia majora Bartholin s duct Prepuce

More information

CASE REPORT GRANULOMA ANNULARE MIMICKING SARCOIDOSIS AND TREATED WITH ACITRETIN: A CASE REPORT

CASE REPORT GRANULOMA ANNULARE MIMICKING SARCOIDOSIS AND TREATED WITH ACITRETIN: A CASE REPORT GRANULOMA ANNULARE MIMICKING SARCOIDOSIS AND TREATED WITH ACITRETIN: A CASE REPORT M.G. Gopal 1, Divya Gupta 2, Sharath Kumar B.C 3, Ramesh M 4, Nandini 5 HOW TO CITE THIS ARTICLE: MG Gopal, Divya Gupta,

More information

Clinical profile of skin diseases in accident and emergency department attenders

Clinical profile of skin diseases in accident and emergency department attenders Hong Kong J. Dermatol. Venereol. (2007) 15, 4-9 Original Article Clinical profile of skin diseases in accident and emergency department attenders CY Chan, KL Kam, CA Graham, TH Rainer, NM Luk Skin problems

More information

Acitretin for Severe Lichen Sclerosus of Male Genitalia: A Randomized, Placebo Controlled Study

Acitretin for Severe Lichen Sclerosus of Male Genitalia: A Randomized, Placebo Controlled Study Acitretin for Severe Lichen Sclerosus of Male Genitalia: A Randomized, Placebo Controlled Study D. Ioannides, E. Lazaridou,* Z. Apalla, E. Sotiriou, S. Gregoriou and D. Rigopoulos From the First Department

More information

Allergy, Atopy and Skin Cancer

Allergy, Atopy and Skin Cancer M. Shane Cahpman, MD, MBA: Dartmouth School of Medicine Boni E. Elewski, MD: University of Alabama Kenneth J. Tomecki, MD: Cleveland Clinic Ted Rosen, MD: Baylor College of Medicine Clinical and Therapeutic

More information

Professor Adrian Mindel

Professor Adrian Mindel Causes of genital ulceration viruses and others Professor Adrian Mindel University of Sydney VIM 16 th August 2012 Outline Definition Causes Epidemiology Diagnosis Definition of genital ulcer A defect

More information

Chronic Radiodermatitis Following Percutaneous Coronary Interventions

Chronic Radiodermatitis Following Percutaneous Coronary Interventions Chronic Radiodermatitis Following Percutaneous Coronary Interventions Jung-Yi Chan Chia-Yu Chu The incidence of radiodermatitis after percutaneous coronary interventions is rising with the increasing number

More information

Egyptian Dermatology Online Journal Vol. 5 No 2:16, December Squamous Cell Carcinoma Arising on Extensive and Chronic Lupus Vulgaris

Egyptian Dermatology Online Journal Vol. 5 No 2:16, December Squamous Cell Carcinoma Arising on Extensive and Chronic Lupus Vulgaris Squamous Cell Carcinoma Arising on Extensive and Chronic Lupus Vulgaris Pathak D.* and Thapa A** Egyptian Dermatology Online Journal 5 (2): 16 * Consultant Dermatologist, Delhi Dermatology Group Kubba,

More information

Gunasundari October 15, :57 PM 13:57 4 Color Fig(s):0 Art: GOX-D

Gunasundari October 15, :57 PM 13:57 4 Color Fig(s):0 Art: GOX-D Original Article Reconstructive Use of Platelet-rich Plasma for Vulvovaginal Autoimmune Conditions Like Lichen Sclerosus AQ1 AQ2 Fariba Behnia-Willison, MBBS, MIS, FRANZCOG* Nina R. Pour, O&G SRMO-DRANZCOG

More information

Safety and Tolerability of Adjuvant Topical Tacrolimus Treatment in Boys with Lichen Sclerosus: A Prospective Phase 2 Study

Safety and Tolerability of Adjuvant Topical Tacrolimus Treatment in Boys with Lichen Sclerosus: A Prospective Phase 2 Study european urology 54 (2008) 932 937 available at www.sciencedirect.com journal homepage: www.europeanurology.com Pediatric Urology Safety and Tolerability of Adjuvant Topical Tacrolimus Treatment in Boys

More information

Genital lichen sclerosus/balanitis xerotica obliterans in men with penile carcinoma: a critical analysis

Genital lichen sclerosus/balanitis xerotica obliterans in men with penile carcinoma: a critical analysis Genital lichen sclerosus/balanitis xerotica obliterans in men with penile carcinoma: a critical analysis Prodromos Philippou, Majid Shabbir, David J. Ralph, Peter Malone, Raj Nigam, Alex Freeman*, Asif

More information

Lymphotropic Virus Type 1 Infection

Lymphotropic Virus Type 1 Infection JOURNAL OF CLINICAL MICROBIOLOGY, Sept. 1992, p. 2487-2491 0095-1137/92/092487-05$02.00/0 Copyright 1992, American Society for Microbiology Vol. 30, No. 9 Immunoelectron Microscopy for Rapid Diagnosis

More information

BJD British Journal of Dermatology. 1.0 Purpose and scope. 2.0 Methodology GUIDELINE

BJD British Journal of Dermatology. 1.0 Purpose and scope. 2.0 Methodology GUIDELINE GUIDELINE BJD British Journal of Dermatology British Association of Dermatologists guidelines for the management of lichen sclerosus, 2018* F.M. Lewis id, 1,2 F.M. Tatnall, 3 S.S. Velangi, 4 C.B. Bunker,

More information

Original Research Article. Lalremruati Sailo 1, Th Bijayanti Devi 1, Th Bhimo Singh 2, Bishurul N. A. Hafi 1 *

Original Research Article. Lalremruati Sailo 1, Th Bijayanti Devi 1, Th Bhimo Singh 2, Bishurul N. A. Hafi 1 * International Journal of Research in Dermatology http://www.ijord.com Original Research Article DOI: http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20175374 Dermatological manifestations of acquired

More information

Erythema gyratumrepens-like eruption in a patient with epidermolysisbullosaacquisita associated with ulcerative colitis

Erythema gyratumrepens-like eruption in a patient with epidermolysisbullosaacquisita associated with ulcerative colitis Erythema gyratumrepens-like eruption in a patient with epidermolysisbullosaacquisita associated with ulcerative colitis A. España C. Sitaru* M. Pretel L. Aguado J. Jimenez# Department of Dermatology, University

More information