STATE-OF-ART IN WHOLE BODY CRYOTHERAPY

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1 STATE-OF-ART IN WHOLE BODY CRYOTHERAPY Agnieszka Piotrowska Assistant Professor Wrocław University of Technology R&D Manager CREATOR Cryogenics Cryogenic Cluster Day 06, Sept. 0th

2 Outlines Low temperatures in medicine Cryochambers Construction overwiev Safety aspects Conclusions

3 Cryomedicine - introduction CRYOMEDICINE CRYOTHERAPY to activate defensive reaction CRYOSURGERY to destroy pathological cells LOCAL WHOLE BODY SPRAY CONTACT NITROGEN (vapor) NITROGEN (liquid) NITROGEN (vapor-liquid mix) NITROGEN (liquid) CO (vapor) AIR (liquid) NITROUS OXIDE (vapor-liquid mix) NITROUS OXIDE (vapor-liquid mix) COOLED AIR REFRIGERANTS (pure and mixture) CO (vapor-liquid mix)

4 Cryomedicine - introduction CRYOMEDICINE CRYOTHERAPY to activate defensive reaction CRYOSURGERY to destroy pathological cells LOCAL WHOLE BODY SPRAY CONTACT NITROGEN (vapor) NITROGEN (liquid) NITROGEN (vapor-liquid mix) NITROGEN (liquid) CO (vapor) AIR (liquid) NITROUS OXIDE (vapor-liquid mix) NITROUS OXIDE (vapor-liquid mix) COOLED AIR REFRIGERANTS (pure and mixture) CO (vapor-liquid mix)

5 Market development for cryochambers in Poland Number of cryochambers in Poland year

6 Market development for cryochambers in Poland Number of cryochambers in Poland year CRYOTHERAPEUTICAL TREATMENT

7 Market development for cryochambers in Poland Number of cryochambers in Poland year CRYOTHERAPEUTICAL TREATMENT SPORT

8 Market development for cryochambers in Poland Number of cryochambers in Poland year CRYOTHERAPEUTICAL TREATMENT SPORT WELLNESS, SPA

9 Cryochambers - introduction 978 First cryochamber Japan 98 First cryochaber in Europe - Germany 989 First cryochamber in Poland 000 First cryosauna 004 First cold retention cryochamber 05 First mobile cryochamber

10 Cryochambers CRYOCHAMBERS WROCLAW-TYPE COOLING RETENTION CRYOSAUNA STATIONARY MOBILE LIQUID NITROGEN LIQUID NITROGEN LIQUID NITROGEN LIQUID LIQUID LIQUID COMPRESSOR UNIT Cryochamber stationary (liquid nitrogen) Cryochamber (compressor unit) Mobile cryochamber Cooling retention cryochamber Cryosauna Courtesy of Creator Zimmer KrioSystem Life Metrum CryoFlex JUKA

11 Cryochambers CRYOCHAMBERS CRYOSAUNAS WROCLAW-TYPE SINGLE COOLING RETENTION FIXED/ STATIONARY MOBILE COLD GAS (AIR) COLD GAS (NITROGEN) LIQUID NITROGEN LIQUID NITROGEN COMPRESSOR UNIT LIQUID LIQUID Cryochamber stationary (liquid nitrogen) Cryochamber (compressor unit) Mobile cryochamber Cooling retention cryochamber Cryosauna Courtesy of Creator Zimmer KrioSystem Life Metrum CryoFlex JUKA

12 Cryochambers construcions CRYOCHAMBERS CRYOSAUNAS WROCLAW-TYPE SINGLE COOLING RETENTION FIXED/ STATIONARY MOBILE COLD GAS (AIR) COLD GAS (NITROGEN) LIQUID NITROGEN LIQUID NITROGEN COMPRESSOR UNIT LIQUID LIQUID

13 Cryochambers construcions CRYOCHAMBERS CRYOSAUNAS WROCLAW-TYPE SINGLE COOLING RETENTION FIXED/ STATIONARY MOBILE COLD GAS (AIR) COLD GAS (NITROGEN) LIQUID NITROGEN LIQUID NITROGEN COMPRESSOR UNIT LIQUID LIQUID

14 Wroclaw-type cryochamber HEAT EXCHANGERS MAIN CHAMBER -0 C to -60 C N PRECHAMBER - 60 C Courtesy of KrioSystem Life and Creator AIR INLET AIR OUTLET AIR DRYER LN TANK

15 Wroclaw-type cryochamber Courtesy of KrioSystem Life and Creator

16 Wroclaw-type cryochamber Courtesy of KrioSystem Life and Creator

17 Cryochamber compressor unit icelab Zimmer MedizinSysteme

18 Cryochamber construcions CRYOCHAMBERS CRYOSAUNAS WROCLAW-TYPE SINGLE COOLING RETENTION FIXED/ STATIONARY MOBILE COLD GAS (AIR) COLD GAS (NITROGEN) LIQUID NITROGEN LIQUID NITROGEN COMPRESSOR UNIT LIQUID LIQUID

19 Single cold air cryochamber Courtesy of Cryoscience

20 Cryochambers construcions CRYOCHAMBERS CRYOSAUNAS WROCLAW-TYPE SINGLE COOLING RETENTION FIXED/ STATIONARY MOBILE COLD GAS (AIR) COLD GAS (NITROGEN) LIQUID NITROGEN LIQUID NITROGEN COMPRESSOR UNIT LIQUID LIQUID

21 Cryochamber with cooling-retention effect RAIL MAIN CABIN WINDOW TANK STEPS NOZZLE SYSTEM

22 Cryochamber with cooling-retention effect RAIL -60 C MAIN CABIN WINDOW TANK STEPS -0 C NOZZLE SYSTEM

23 Cryochamber with cooling-retention effect TANK -60 C -0 C % O 79% N

24 Phase equilibrium of N-O mixture VAPOUR TEMPERATURE, K VAPOR 90K LIQUID 78K 79% N % O LIQUID 00% N 0% N 0% O 00% O

25 Cryochamber with cooling-retention effect ODH ALERT! TANK -60 C 90% N -0 C

26 Cryochambers construcions CRYOCHAMBERS CRYOSAUNAS WROCLAW-TYPE SINGLE COOLING RETENTION FIXED/ STATIONARY MOBILE COLD GAS (AIR) COLD GAS (NITROGEN) LIQUID NITROGEN LIQUID NITROGEN COMPRESSOR UNIT LIQUID LIQUID

27 Cryosauna PANEL N COLD-GAS LINE N EVAPORATOR LIQUID NITROGEN TANK N OUTLET LIFT

28 Cryosauna % O, 79% N?% O,?% N?% O,?% N?% O,?% N

29 Cryosauna cm C 50 cm C 40 cm C 30 cm C 0 cm C 0 cm C 0 cm

30 Cryosauna ODH ALERT! cm C 50 cm C 40 cm C 30 cm C 0 cm C 0 cm C 0 cm

31 October 05

32

33 Supply systems of chambers SUPPLY SYSTEM OPEN Direct contact between user and colling medium CLOSED NO direct contact between user and cooling medium COOLING RETENTION EFFECT Synthetic air WROCLAW-TYPE (stationary and mobile) Liquid nitrogen Compressor unit CRYOSAUNA Liquid nitrogen SINGLE - COLD AIR Nitrogen and air

34 Supply systems of chambers SUPPLY SYSTEM OPEN Direct contact between user and colling medium CLOSED NO direct contact between user and cooling medium COOLING RETENTION EFFECT Synthetic air WROCLAW-TYPE (stationary and mobile) Liquid nitrogen Compressor unit CRYOSAUNA Liquid nitrogen SINGLE - COLD AIR Nitrogen and air

35 Summary. Poland is a country where cryotherapy is well recognized, developped and appreciated both from medical and technical point of view. Accumulated number of cryotherapeutical treatments in Poland approaches 3 millions (in comparison of 500 k for the rest of Europe).. Four different constructions of chambers dedicated to the cryotherapeutical sessions have been developed and are commercially available right now. 3. Supply systems of cryochambers shouldn t allow for direct contact between user and cooling medium (nitrogen) due to the safety reasons. Therefore, cryosaunas shouldn t be considered as whole body cryochambers.

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