Connective tissue diseases by the numbers

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1 AMERICAN ACADEMY OF DERMATOLOGY SKIN DISEASE BRIEFS Connective tissue diseases by the numbers Connective tissue diseases are among 24 skin diseases or disease categories examined in the Burden of Skin Disease report commissioned by the American Academy of Dermatology. The report examined prevalence, economic burdens, and mortality for skin disease in the U.S. using 2013 health care claims data drawn from insurance enrollment and claims databases and found that: 84.5 million Americans one in four saw a physician for skin disease; 50% of them are over 65 and have an average of 2.2 skin conditions. Skin disease cost the U.S. healthcare system $75 billion in medical, preventative, and prescription and non-prescription drug costs. One in three Americans with skin disease were seen by a dermatologist, who collaborate with other physicians throughout the health care system in caring for these patients. Connective tissue diseases include serious conditions such as lupus, dermatomyositis, scleroderma, and diffuse connective tissue disease which together resulted in nearly 1,400 deaths in That year, connective tissue diseases: Affected more than 1.16 million individuals, primarily adults. Were among the top 5 costliest skin diseases per patient at $1,177; total medical costs were $1.38 billion. Resulted in lost productivity costs for individuals and caregivers of $122 million, higher than that of psoriasis or melanoma. Decreased the average of lifespan of 75 years by almost 19 years, more than twice as much as all other causes of death. The charts that follow provide topline data on how connective tissue diseases contribute to the overall burden of skin disease. The full report includes data on prescription and non-prescription drug costs, and how age and insurance status and provider relate to the burden associated with connective tissue diseases and skin disease broadly. To purchase the report visit

2 Prevalance NUMBER OF CARED-FOR INDIVIDUALS TISSUE 30,000,000 25,000,000 20,000,000 15,000,000 10,000,000 5,000, ,169,094 NON-CANCEROUS SKIN GROWTHS* VIRAL AND FUNGAL WOUNDS AND BURNS CONTACT DERMATITIS TISSUE *This category is clinically broad in nature and includes, among other diseases: benign neoplasms, melanocytic nevi (unspecified), pilar cysts, pilonidal cysts (with or without abscess), scars and fibrosis, etc. TISSUE DISEASE PATIENTS BY AGE* 50.0% 45.0% 44.0% 40.0% 35.0% 30.0% 25.0% 20.0% 15.0% 10.0% 23.9% 0.34% 30.3% 5.0% 0.0% 1.9% *Percentage of connective tissue disease patients seen by a physician by age group.

3 Cost TOTAL MEDICAL COST* TISSUE (IN MILLIONS USD) $9,000 $8,000 $7,000 $6,000 $5,000 $4,000 $3,000 $8,135 $7,015 $6,398 $6,052 $5,442 $2,000 $1,000 $0 $1,375 NON-CANCEROUS SKIN GROWTHS** WOUNDS AND BURNS SKIN CANCER*** ULCERS TISSUE * In millions of dollars compared to most costly skin diseases. **This category is clinically broad in nature and includes, among other diseases: benign neoplasms, melanocytic nevi (unspecified), pilar cysts, pilonidal cysts (with or without abscess), scars and fibrosis, etc. ***Represents combined data for melanoma and nonmelanoma skin cancer. COST OF SKIN DISEASE PER AFFECTED PERSON* TISSUE $3, $3, $2, $2, $1, $1, $1, $ $0.00 LYMPHOMA SKIN CANCER** ULCERS TISSUE BULLOUS *Compared with most costly skin diseases. **Represents combined data for melanoma and nonmelanoma skin cancer.

4 Life Impact MORTALITY* TISSUE 5,000 4,500 4,000 NUMBER OF DEATHS IN ,500 3,000 2,500 2,000 1,500 1, , Y SKIN CANCER 3, Y WOUNDS AND BURNS 2, Y 1, Y ULCERS 1, Y TISSUE *Provides the total number of deaths and average age at death from connective tissue diseases compared with other skin diseases with highest mortality. YEARS OF POTENTIAL LIFE LOST* TISSUE TOTAL SKIN ALL CAUSES OF DEATH ALL CAUSES OF DEATH TOTAL SKIN WOUNDS AND BURNS CONGENITAL ABNORMALITIES TISSUE *Estimate/projected number of life years lost due to connective tissue diseases compared to top skin diseases leading to early death; Projected based on prototypical lifespan of 75 years.

5 Life Impact LOST PRODUCTIVITY (OPPORTUNITY COST)* TISSUE $2,500 (IN MILLIONS USD) $2,000 $1,500 $1,000 $1,924 $1,570 $1,413 $940 $699 $500 $0 $122 NON-CANCEROUS WOUNDS SKIN GROWTHS** AND BURNS VIRAL AND FUNGAL DISEASE CONTACT DERMATITIS TISSUE *Time lost by patients and/or caregivers multiplied by average wages in 2013 ($192/day); In millions of dollars compared with skin diseases leading to the most loss of productivity. **This category is clinically broad in nature and includes, among other diseases: benign neoplasms, melanocytic nevi (unspecified), pilar cysts, pilonidal cysts (with or without abscess), scars and fibrosis, etc.

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