Please answer the following questions by circling the best response, or by filling in the blank.
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1 1 Please answer the following questions by circling the best response, or by filling in the blank. Demographics Age: Gender: a. Male b. Female Race: a. White d. American Indian/Alaskan Native b. Black or African American e. Pacific Islander/Native Hawaiian c. Asian f. Other (specify) Ethnicity: a. Hispanic or Latino b. Not Hispanic or Latino Profession: a. Physician b. Physician s Assistant c. Nurse/Advanced Nurse Practitioner d. Phlebotomist e. Other (specify) Current TPMT Genotyping Procedures 1. Is TPMT genotyping to guide dosing of thiopurine medications (i.e., mercaptopurine and thioguanine) currently part of your routine clinical care? 2. If yes, who is primarily responsible for returning TPMT genetic test results to patients? a. Physician b. Physician Assistant c. Nurse/advanced nurse practitioner d. Genetic counselor e. Other (specify)
2 2 3. Is TPMT phenotyping (enzyme assay) currently a part of your routine clinical care? 4. Is thiopurine metabolite monitoring currently a part of your routine clinical care? 5. How often do you use TPMT genotype results to determine the initial dose for the thiopurines? 6. Have there been instances when thiopurine treatment has been postponed because TPMT genotype results were not available? 7. Have there been instances when thiopurine treatment has been postponed because TPMT genotype results were not easily accessible? 8. Are you able to find TPMT genotype results easily within the electronic medical record? 9. Are you able to find TPMT genotype results consistently within the electronic medical record?
3 3 10. Are the TPMT genotype results presented in a user-friendly manner within the electronic medical record? 11. Do you currently receive the TPMT genotype results in a timely manner? 12. What is your estimate of the average turnaround time (in business days) for the TPMT genotype results? a. 1-3 days b. 4-6 days c. 7-9 days d. >9 days e. I do not know 13. I am satisfied with the current process for ordering TPMT genotype testing. 14. Our current process for returning TPMT genetic test results to patients are appropriate to meet patients needs.
4 4 15. I can accurately apply the results of the TPMT genotype test to: (circle all that apply) a. Drug therapy dosing b. Drug therapy monitoring c. I cannot accurately apply the results of the TPMT genotype test d. Other (specify): 16. I understand the role that TPMT genotype testing plays in adjusting the dose of thiopurines clinically. Updated TPMT Genotyping Procedures 17. I understand the rationale behind new procedures for TPMT genotyping within UF Health. 18. I feel that the new procedures for TPMT genotype test ordering will be beneficial to patient care.
5 5 19. I feel that the new procedures for TPMT genotype test result documentation in the medical record will be beneficial to patient care. 20. Clinical decision support in the electronic medical record (i.e., Epic alert) is an effective strategy to support TPMT genotype test ordering. 21. Clinical decision support in the electronic medical record (i.e., Epic alert) is an effective strategy to support thiopurine dose adjustment based on TPMT genotype test results. 22. I know who to contact if I have questions about the new TPMT genotype test ordering procedures.
6 6 General Pharmacogenomics 23. I believe that using genetics to guide therapeutic choices improves my ability to reduce adverse drug events. 24. I believe that using genetics to guide therapeutic choices improves my ability to choose an effective treatment strategy for patients. 25. I believe that pharmacogenetics is relevant to my current clinical practice. 26. I am able to identify reliable sources of pharmacogenetic information in patient care.
7 7 27. I am able to use reliable sources of pharmacogenetic information in patient care. 28. I am able to identify reliable sources of pharmacogenetic information for patient education. 29. I am able to use reliable sources of pharmacogenetic information for patient education. 30. The UF Health Personalized Medicine Program enhances my ability to care for patients.
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