SmartSensor telemed Home OGTT Kit

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1 SmartSensor telemed Home OGTT Kit NFC & Cloud Enabled Screening for Diabetes James Jackson, CEO, Oxford Roy Kelly, Chairman, Port St Mary

2 Having an OGTT Today Assesses how the body handles glucose Remember to stay fasted and as rested as possible before the test Glucose levels before and after the drink are diagnostic for all forms of diabetes The gold standard diabetes test Clinic based OGTT is difficult and expensive to provide and hard to access OGTT is substantially underprovided

3 SmartSensor s Home OGTT Everything needed to perform an OGTT at home Powered by SmartSensor s wireless OGTT device No training, supervision or additional equipment required After test, simply snap off the Data Record Data on the Data Record is processed by SmartSensor

4 OGTT Data Processing Enabled by smartphones, apps and online services (Cloud) Device data output NFC (wireless) Tailored to target user or market SmartSensor Data Record NFC to phone Mail Results & healthcare delivery Support multiple service models Drop-off Data processed Results stored in electronic record Doctor, nurse Pharmacist Telephone helpline Online to EPR SMS & Apps

5 Who Gets Diabetes? Why is OGTT Relevant? Type 1 diabetes is genetic in nature and accounts for up to 5% of diabetes globally

6 Prediabetes Fuels the Type 2 Diabetes Epidemic Target Population Burgeoning cost of diabetes 2+ billion people American Diabetes Association December 2014 Around the same numbers again have prediabetes OGTT is the only sensitive and specific prediabetes test

7 Pregnancy - Gestational Diabetes, GDM Affects 18% of pregnancies OGTT is the only recommended screening test

8 GDM Leads to Type 2 Diabetes OGTT is the most recommended monitoring test From Changing Diabetes in Pregnancy Bio Business Conference 11 th December 2014

9 Diabetes in Cystic Fibrosis 50% of patients develop diabetes by age 30 Visiting the clinic for tests is dangerous due to risk of picking up infections From Changing Diabetes in Pregnancy OGTT is the only recommended test

10 Diabetes in Other Conditions Organ Transplants 20% to 50% of patients develop diabetes within 1 year Ovarian Cysts, PCOS Up to 7 fold increased risk of developing type 2 diabetes Infectious Diseases HIV TB Sleep Apnoea Up to 40% of patients have diabetes OGTT is the only test or the most recommended test In all cases it is terribly underutilised From Changing Diabetes in Pregnancy

11 Summary of Home OGTT opportunity Investment opportunity seeking 3m to launch product profitably Full Information Memorandum and financials available Design and development completed Backed by significant funding from Novartis and existing investors Large niches for first sales - pregnancy and others High clinical impact, high cost of late diagnosis; OGTT the only test Demonstrators with major centres, early 2015 King s College Hospital - 80% of London s pregnant women qualify for an OGTT Great Ormond Street Hospital - low coverage of screening in cystic fibrosis Substantial opportunities in prediabetes (IGT) and type 2 diabetes Today ½ of type 2 is undiagnosed. 2035: 600 million cases of type million of IGT Product pipeline extending to cardiovascular disease and other conditions

12 Thank You James Jackson, CEO SmartSensor Telemed