Non-Insulin Diabetes Medications Summary
|
|
- Michael Morris
- 5 years ago
- Views:
Transcription
1 Non-Insulin Diabetes Medications Summary Medications marked with an asterisk (*) can cause hypoglycemia INSULIN SECRETAGOGUES Sulfonylureas* GLYBURIDE* (Diabeta) (Micronase) production. Side effects: Potential for hypoglycemia. 1.25, 2.5, times/day Take to avoid hypoglycemia MICRONIZED GLYBURIDE* (Glynase Prestabs) 1.5, 3, times/day With meals GLIPIZIDE* (Glucotrol) 5, times/day 30 minutes pre-meal GLIPIZIDE EXTENDED RELEASE* (Glucotrol XL) 2.5, 5, times/day With meals 5 20 GLIMEPIRIDE* (Amaryl) 1, 2, 4 1 time/day With meals Meglitinides* REPAGLINIDE* (Prandin) production. Side effects: Potential for hypoglycemia 0.5, 1, 2, times/day, 0 30 min pre meals Skip meal, skip dose Add meal, add dose to total of 4 doses/day D-Phenylalanine Derivative* NATEGLINIDE* (Starlix) production. Side effects: Potential for hypoglycemia 60, times/day, 0 30 min pre meals Skip meal, skip dose Rev 5.14
2 GLUCOSE SUPPRESSORS Biguanides METFORMIN (Glucophage) Action: Decreases hepatic glucose production, and improves glucose transport. Side effects: Gas, diarrhea, lactic acidosis. To decrease lactic acidosis risk, avoid in: - Liver disease, alcohol abuse/bingeing- If creatinine 1.4 mg/dl in women; 1.5 mg/dl in men - IV contrast - Recurrent CHF - Severe infection, acute MI - 80 years age unless creatinine clearance is normal. Hold for IV contrast dye, surgery or severe vomiting or diarrhea. Repeat creatinine in 48 hrs; if OK, restart metformin. 500, 850, times/day Take to avoid stomach upset : Take with food to decrease gas, diarrhea. METFORMIN EXTENDED RELEASE (Glucophage XR) 500, times/day METFORMIN EXTENDED RELEASE (Fortamet) 500, time/day METFORMIN EXTENDED RELEASE (Glumetza) 500, time/day METFORMIN ORAL SOLUTION (Riomet) 500mg (5ml) 2 3 times/day
3 MED GROUP DESCRIPTOR INSULIN SENSITIZERS Thiazolidinediones ROSIGLITAZONE (Avandia) Note: The FDA has now determined that in addition to describing the cardiovascular risks (such as heart attack or stroke ) of rosiglitazone and rosiglitazone-containing medicines the drug labels must be revised to state that use of the drug is limited to: Patients already being treated with these medicines Patients whose blood glucose cannot be controlled with other antidiabetic medicines and who, after consulting with their healthcare professional, do not wish to use pioglitazone-containing medicines (Actos, Actoplus Met, Actoplus Met XR, Duetact or Oseni). Action (both): Improves glucose transport, and decreases hepatic glucose production. May have beneficial effect on endothelium. Side effects (both): Weight gain, fluid retention, osteopenia, increase in CHF in those at risk. Liver disease check LFTs at baseline then periodically. (both): May cause resumption of ovulation in perimenopausal women. Take same time daily May require up to 2 weeks to see an effect. Maximum recommended dosage of pioglitazone 15mg/day with drugs that are strong inhibiters of CYP2C8, such as gemfibrozil. 2, 4, times/day Same time daily 4 8 PIOGLITAZONE (Actos) 15, 30, 45 1 time/day Same time daily DPP-4 INHIBITORS SITAGLIPTIN (Januvia) SAXAGLIPTIN (Onglyza) LINAGLIPTIN (Tradjenta) ALOGLIPTIN (Nesina) Action: Slows the inactivation of incretin hormones, resulting in increased insulin synthesis and decreased glucagon levels in a glucose-dependent manner. Side effects: URI, stuffy nose, sore throat, occasional diarrhea and stomach discomfort. (UTI with Onglyza) : Decrease dose for renal disease with sitagliptin, saxagliptin and alogliptin. No dosage adjustment is needed with linagliptin Watch for interactions with drugs that induce P-glycoprotein or CYP450 3A4 enzymes (with linagliptin), or inhibit CYP 3A4 enzymes (with saxagliptin) 25, 50, , , 12.5, time/day unrelated to food. Same time daily 1 time/day unrelated to food. Same time daily 1 time/day unrelated to food. Same time daily 1 time/day unrelated to food. Same time daily
4 STARCH BLOCKERS Alpha-Glucosidase Inhibitors MIGLITOL (Glyset) ACARBOSE (Precose) Action: Delays absorption and breakdown of carbohydrates from intestines. Side effects: Gas, diarrhea. Elevation of LFTs with acarbose in doses >50mg tid, and wt < 132 lbs. : Use glucose to treat hypoglycemia when used in combination therapy Dose low and increase slowly to decrease flatulence 25, 50, times/day with first bite of meal 25, 50, times/day with first bite of meal GLUCOSE EXCRETORS SGLT2 Inhibitors CANAGLIFLOZIN (Invokana) DAPAGLIFLOZIN (Farxiga) EMPAGLIFLOZIN (Jardiance) Action: Lowers blood glucose by reducing renal glucose reabsorption and increasing urinary glucose excretion. Side effects: UTI, increased urination, genital fungal infection, hypoglycemia when used with insulin or insulin secretagogues, dehydration, thirst, hypotension, increased LDL cholesterol, weight loss, hyperkalemia (in canagliflozin); possible risk of bladder cancer (in dapagliflozin) : Dose of canagliflozin may be increased to 300 mg/day if egfr 60 and further glycemic control needed. Avoid use in patients with egfr <45. Contraindicated in patients with severe renal impairment, ESRD or on dialysis. Do not use if patients have severe renal impairment (for canagliflozin, egfr less than 30 ml/min during dialysis; for dapagliflozin, egfr < 60 ml/min) time/day taken before first meal of the day time/day taken in the morning, with or without food Once daily 10 or 25
5 BILE ACID SEQUESTRANTS COLESEVELAM (Welchol) Action: Bile acid sequestrant that reduces LDL cholesterol and improves glycemic control. Side effects: constipation, nausea, diarrhea, gas, heartburn, headache. May interact with glyburide, levothyroxine and contraceptives. 625 mg tablet 1.875g, 3.75g powder packet 6 tablets (or 3.75g powder packet) daily or 3 tablets (or 1.875g powder packet) twice daily with a meal and liquid
6 MED GROUP DESCRIPTOR DOPAMINE AGONIST BROMOCRIPTINE MESYLATE* (Cycloset) Action: Unknown; lowers glucose without increasing insulin. Reduces the risk of MI and stroke. 0.8mg 1 time/day with food within 2 hrs of waking Side effects: hypotension, orthostatic changes, fainting, drowsiness, may worsen psychotic disorders, hypoglycemia, nausea, fatigue, severe dizziness. FIXED COMBINATIONS GLYBURIDE and METFORMIN* (Glucovance) GLIPIZIDE and METFORMIN* (Metaglip) production and decreases hepatic glucose production. sulfonylureas and biguanides mg/ /500 5 / / /500 5 / times/day 1 2 times/day ROSIGLITAZONE and METFORMIN (Avandamet ) Action: Improves glucose transport, and decreases hepatic glucose production. thiazolidinediones and biguanides. 1 /500 2 /500 4 /500 2 / / times/day PIOGLITAZONE and METFORMIN (Actoplus Met) Action: Improves glucose transport, and decreases hepatic glucose production. thiazolidinediones and biguanides. 15 / / times/day / REPAGLINIDE and METFORMIN (Prandimet) production and decreases hepatic glucose production. meglitinides and biguanides 1 /500 2 / times/day 15 minutes premeal Skip meal, skip dose ; Max dose 10 /2500 CANAGLIFLOZIN and METFORMIN (Invokamet) Action: Lowers blood glucose by reducing renal glucose reabsorption and increasing urinary glucose excretion. Decreased hepatic glucose production Side effects: See above information for canagliflozin and Biguanides 50/500 50/ / / times/day with breakfast and supper 50 or 150/500 or 1000 See note under thiazolidinediones regarding limitations on use
7 ROSIGLITAZONE and GLIMEPIRIDE* (Avandaryl ) Action: Improves glucose transport, decreases hepatic glucose production and stimulates β-cell insulin production. thiazolidinediones and sulfonylureas. 4 /1 4 /2 4 /4 1 time/day with first meal PIOGLITAZONE and GLIMEPRIDE* (Duetact) ALOGLIPTIN and PIOGLITAZONE (Oseni) SITAGLIPTIN and METFORMIN (Janumet) SITAGLIPTIN and METFORMIN ER (Janumet XR) SAXAGLIPTIN and METFORMIN ER (Kombiglyze XR) Action: Improves insulin action in adipose tissue, liver, and skeletal muscle; May have beneficial effect on vascular cells and β cells, stimulates β-cell insulin production. pioglitazone and glimepiride. See above for alogliptin See above for pioglitazone Action: Slows the inactivation of incretin hormones, resulting in increased insulin synthesis and decreased glucagon levels in a glucose dependent manner. Decreases hepatic glucose production, and improves glucose transport. sitagliptin, saxagliptin, linagliptin, alogliptin and metformin. Reduce Kombiglyze to 2.5 mg/1000 if also taking strong CYP3A4/5 inhibitors, such as ketoconazole. 15, 30, 45 1 time/day before first meal 12.5/ / /45 50/500 50/1000 5/500 5 / /1000 Start at 15 /day; Increase every 4 to 8 weeks or more, as needed, to 30 /day, and then to 45 /day 1 time/day 2 times/day, taken with food 1 time/day with evening meal 1 time/day with evening meal LINAGLIPTIN and METFORMIN (Jentadueto) Consider alternative treatment to Jentadueto if CYP3A4 or P-gp inducers are taken. 2.5/ / / times/day, taken with food ALOGLIPTIN and METFORMIN (Kazano) 12.5/ / times/day, taken with food SITAGLIPTIN and SIMVASTATIN (Juvisync) Action: See above for sitagliptin. Simvastatin is an HMG-CoA reductase inhibitor (statin) that inhibits the enzyme that catalyzes the conversion HMG-CoA to mevalonate (an early and ratelimiting step in cholesterol biosynthesis), thereby decreasing total cholesterol, LDL cholesterol, Apo B and triglycerides. sitagliptin. Side effects for simvastatin may include URI, headache, abdominal pain, myopathy and rhabdomyolysis. See note under Thiazolidinediones regarding limitations on use 100/10 100/20 100/40 1 time/day in the evening. amount of simvastatin required to achieve lipid goals. Start at 100/40 per day.
8 Injectables GLP-1 Receptor Agonists* EXENATIDE (Byetta) LIRAGLUTIDE (Victoza) EXENATIDE EXTENDED-RELEASE (Bydureon) TANZEUM (Albiglutide) Amylin mimetic* PRAMLINTIDE (Symlin) Action: Increases the level of incretin hormones, resulting in enhanced insulin secretion and reduced glucagon secretion in a glucosedependent manner. Side Effects: Contraindicated in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2) Pancreatitis, hypoglycemia can occur when used in combination with insulin or secretagogues. Common side effects include nausea vomiting or diarrhea, reactions at the injection site, cough, back pain and cold or flu symptoms Action: Exact mechanism unknown. Decreases postprandial glucose suppresses glucagon secretion, slows gastric emptying similar to GLP-1 agonists. Side Effects: Nausea, anorexia, vomiting. 5,10 mcg/dose (multi-dose prefilled pen) 0.6, 1.2, 1.8 mg/dose (multi-dose prefilled pen) 2 mg by subcutaneous injection 30,50 mg/single-dose pen Type 2 60 mcg to 120 mcg (multidose prefilled pen) Type 1 15 mcg to 60 mcg (multidose prefilled pen) 2 times/day 0-60 min pre-meals (6+ hours apart) mcg/day 1 time/day mg/day (initiate at 0.6 mg/day) 1 time every 7 days (once per week) 1 time every 7 days (once per week) Immediately prior to meals containing 250 calories or 30 grams of carbohydrates 2 mg/week 30 to 50 mg/week mcg/day mcg/day
Oral Medication for the Management of Diabetes Mechanism of. Duration of Daily Dosing Action
Glyburide (Micronase, Diabeta, Glynase) Glipizide (Glucotrol) Glipizide XL (Glucotrol XL) Glimepiride (Amaryl) Prandin (Repaglinide) Starlix (Nateglinide) 1.25, 2.5, 5mg tabs, Dosing: 2.5-20 mg 12- (Glynase:
More informationDiabetes Medication Updates Erica Bukovich, PharmD, BC-ADM, CDE September 20, 2018
Diabetes Medication Updates Erica Bukovich, PharmD, BC-ADM, CDE September 20, 2018 Learning Objectives Identify medication classes available for treatment of individuals with diabetes. Demonstrate understanding
More informationDiabetes Medications: Oral Anti-Hyperglycemic Medications
Diabetes Medications: Oral Anti-Hyperglycemic Medications Medication Types 1. Biguanides 2. Sulfonylureas 3. Thiazolidinediones (TZDs) 4. Alpha-Glucosidase Inhibitors 5. D-Phenylalanine Meglitinides 6.
More informationDM Fundamentals Class 4 Meds for Type 2
DM Fundamentals Class 4 Meds for Type 2 Beverly Thomassian, RN, MPH, BC ADM, CDE President, Diabetes Education Services Copyright 1999 2015, Diabetes Education Services, All Rights Reserved. Diabetes Meds
More informationWhat s New in Diabetes Treatment. Disclosures
What s New in Diabetes Treatment Shiri Levy M.D. Henry Ford Hospital Senior Staff Physician Service Chief, West Bloomfield Hospital Endocrinology, Metabolism, Bone and Mineral Disorders Disclosures None
More informationObjectives. How Medicine Works to Control Blood Sugar Levels. What Happens When We Eat? What is diabetes? High Blood Glucose (Hyperglycemia)
How Medicine Works to Control Blood Sugar Levels Stacie Petersen, RN, CDE Objectives Define Diabetes List how medications work (ominous octet) Identify side effects of medications for diabetes What is
More informationRPCC Pharmacy Forum. The Type 2 Diabetes Issue. Type 2 Diabetes: The Basics
Nov/Dec 2015 Issue 11 RPCC Pharmacy Forum Special Interest Articles: Diabetes Medication Chart Insulin Chart Afreeza Did you know? Exanatide, marketed as Byetta, is the synthetic form of exendin-4, which
More informationDiabetes Treatment Guidelines
Diabetes Treatment Guidelines For more comprehensive information about current approaches to the diagnosis and treatment of diabetes, visit the American Diabetes Association Standards of Medical Care 2018
More informationOral and Injectable Non-insulin Antihyperglycemic Agents
Appendix 5: Diabetes Education and Medical Management in Adults with Diabetes Oral and Injectable Non-insulin s This directive will be implemented by RPhs, RNs or RDs who have been deemed authorized implementers.
More informationType II Diabetes Improving Blood Sugar Control. Geneva Clark Briggs, Pharm.D., BCPS
Type II Diabetes Improving Blood Sugar Control Geneva Clark Briggs, Pharm.D., BCPS Overview Importance of glucose control State of control Review available therapies Helping patients achieve control The
More informationDM Fundamentals Class 4 Meds for Type 2
DM Fundamentals Class 4 Meds for Type 2 Beverly Thomassian, RN, MPH, BC ADM, CDE President, Diabetes Education Services Copyright 1999 2015, Diabetes Education Services, All Rights Reserved. Diabetes Meds
More informationFARXIGA (dapagliflozin) Jardiance (empagliflozin) tablets. Synjardy (empagliflozin and metformin hydrochloride) tablets. GLUCOPHAGE* (metformin)
Type 2 Medications Drug Class How It Works Brand and Generic Names Manufacturers Usual Starting Dose The kidneys filter sugar and either absorb it back into your body for energy or remove it through your
More informationOral and Injectable Medication Options for Diabetes Treatment
Oral and Injectable Medication Options for Diabetes Treatment Presented by: Dr. Daphne E. Smith, Pharm.D., CDE Clinical Assistant Professor/Clinical Pharmacist-University of Illinois at Chicago College
More informationPharmacologic Agents for Treatment of Type 2 Diabetes
Pharmacologic Agents for Treatment of Type 2 Diabetes SCAN Drugs Medication Biguanides 1 1 er uncoated tabs 500 mg & 750 mg Sulfonylureas 1 1 500 850 mg QD - TID 500 2000 mg glimepiride 1 1 1 8 mg glipizide
More information4/9/2018 HOW TO REGULATE DIABETES MEDICATIONS. By Sarah Froemsdorf MSN, RNC, CDE, FNP DISCLOSURES NONE. Diagnosis
HOW TO REGULATE DIABETES MEDICATIONS By Sarah Froemsdorf MSN, RNC, CDE, FNP DISCLOSURES NONE Diagnosis 1 NORMAL BODY The normal pancreas releases one unit of insulin every hour all day. The normal pancreas
More informationDIABETES. overview of pharmacologic agents used in the management of. Overview 4/3/2014 OBJECTIVES. Injectable Agents
overview of pharmacologic agents used in the management of DIABETES Kyle Roberts, Pharm.D. PGY-1 Pharmacy Resident Saint Alphonsus RMC 1. List the different classes of diabetes medications, including the
More informationORAL AGENTS OLD & NEW FOR THE MANAGEMENT OF T2DM
ORAL AGENTS OLD & NEW FOR THE MANAGEMENT OF T2DM ECHO-Diabetes July 21, 2016 VERONICA BRADY, PHD, FNP-BC, BC-ADM, CDE OBJECTIVES Overview of Diabetes Oral hypoglycemic agents Define various classes of
More informationJonathan Stoehr, MD PhD Endocrinology, Diabetes, Metabolism and Nutrition Virginia Mason Medical Center Seattle, WA 2012 Virginia Mason Medical
Jonathan Stoehr, MD PhD Endocrinology, Diabetes, Metabolism and Nutrition Virginia Mason Medical Center Seattle, WA There is no conflict of interest that could be perceived as prejudicing the impartiality
More informationDiabetes Oral Agents Pharmacology. University of Hawai i Hilo Pre-Nursing Program NURS 203 General Pharmacology Danita Narciso Pharm D
Diabetes Oral Agents Pharmacology University of Hawai i Hilo Pre-Nursing Program NURS 203 General Pharmacology Danita Narciso Pharm D 1 Learning Objectives Understand the role of the utilization of free
More information1/15/2018. Disclosures. Current Diabetes Medications. Objectives NON-INSULIN AGENTS. Diabetes Med Classes. Mealtime
Disclosures Current Diabetes Medications None Claire Baker, M.D. Diabetes & Endocrine Associates January 24, 2018 Objectives Identify categories of diabetes medications Understand the pharmacology of diabetes
More informationType 2 Diabetes: Where Do We Start with Treatment? DIABETES EDUCATION. Diabetes Mellitus: Complications and Co-Morbid Conditions
Diabetes Mellitus: Complications and Co-Morbid Conditions ADA Guidelines for Glycemic Control: 2016 Retinopathy Between 2005-2008, 28.5% of patients with diabetes 40 years and older diagnosed with diabetic
More informationPhysician Drug Reference Chart for Diabetes Antidiabetic Medications
Drug Class Compound Brand Name Mechanism of Action Advantages Disadvantages Alpha-glucosidase inhibitors Medium Cost by Bayer Healthcare, Pfizer, Takeda Research Acarbose Miglitol Voglibose Precose Glyset
More informationI. General Considerations
1 2 3 I. General Considerations A. Type I ( Juvenile Onset or IDDM) IDDM results from autoimmune destruction of beta cells inability to secrete insulin --> ketone formation --> DKA 4 Diabetic Ketoacidosis
More informationPharmacology Updates. Quang T Nguyen, FACP, FACE, FTOS 11/18/17
Pharmacology Updates Quang T Nguyen, FACP, FACE, FTOS 11/18/17 14 Classes of Drugs Available for the Treatment of Type 2 DM in the USA ### Class A1c Reduction Hypoglycemia Weight Change Dosing (times/day)
More informationTable 1. Antihyperglycemic agents for use in type 2 diabetes
Table 1. Antihyperglycemic agents for use in type 2 diabetes DRUG IN ALPHA-GLUCOSIDASE INHIBITOR: inhibits pancreatic alpha-amyle and intestinal alpha-glucoside Acarbose (Glucobay) 0.6% Negligible Not
More informationAntihyperglycemic Agents in Diabetes. Jamie Messenger, PharmD, CPP Department of Family Medicine East Carolina University August 18, 2014
Antihyperglycemic Agents in Diabetes Jamie Messenger, PharmD, CPP Department of Family Medicine East Carolina University August 18, 2014 Objectives Review 2014 ADA Standards of Medical Care in DM as they
More informationWhat the Pill Looks Like. How it Works. Slows carbohydrate absorption. Reduces amount of sugar made by the liver. Increases release of insulin
Diabetes s Oral s - Pills These are some of the pills that are currently available in Canada to treat diabetes. Each medication has benefits and side effects you should be aware of. Your diabetes team
More informationObjectives. Recognize all available medical treatment options for diabetes. Individualize treatment and glycemic target based on patient factors
No disclosure Objectives Recognize all available medical treatment options for diabetes Individualize treatment and glycemic target based on patient factors Should be able to switch to more affordable
More informationVictoza (Liraglutide) Solution for Injection
Texas Prior Authorization Program Clinical Edit Criteria Drug/Drug Class Clinical Edit Information Included in this Document Drugs requiring prior authorization: the list of drugs requiring prior authorization
More informationSociety for Ambulatory Anesthesia Consensus Statement on Perioperative Blood Glucose Management in Diabetic Patients Undergoing Ambulatory Surgery
Society for Ambulatory Anesthesia Consensus Statement on Perioperative Blood Glucose Management in Diabetic Patients Undergoing Ambulatory Surgery Girish P. Joshi, MB BS, MD, FFARCSI Anesthesia & Analgesia
More informationImages have been removed from the PowerPoint slides in this handout due to copyright restrictions. Insulins. Rapid Short Intermediate Long Mix
Diabetes Medications Diabetes Medications Type 1 Insulin is needed Type 2 Oral Diabetes Medications Or Oral Diabetes Medications plus Insulin Or Insulin Alone Diabetes Medications Secretagogues Glipizide
More information6/1/2018. Lou Haenel, IV, DO, FACE, FACOI Endocrinology Roper St Francis Charleston, SC THE OMINOUS OCTET: HOW PATHOPHYSIOLOGY AND THERAPY MERGE
Lou Haenel, IV, DO, FACE, FACOI Endocrinology Roper St Francis Charleston, SC THE OMINOUS OCTET: HOW PATHOPHYSIOLOGY AND THERAPY MERGE 1 2 3 Sulfonylureas Glipizide Glyburide Glimeperide 4 Metformin Gold
More informationQuick Guide MEDICATIONS 7th Edition Evan Sisson, Pharm.D., MHA, CDE
Quick Guide to MEDICATIONS 7th Edition Evan Sisson, Pharm.D., MHA, CDE Adapted from The Art and Science of Diabetes Self-Management Education Desk Reference 2017, American Association of Diabetes Educators,
More informationVery Practical Tips for Managing Type 2 Diabetes
Very Practical Tips for Managing Type 2 Diabetes Jean-François Yale, MD, FRCPC McGill University Health Centre, Montreal, Canada Jean-francois.yale@mcgill.ca www.dryale.ca OBJECTIVES DISCLOSURES The participant
More informationClinical Cases in Diabetes Management. Joseph Cook D.O.
Clinical Cases in Diabetes Management Joseph Cook D.O. Objectives State the prevalence of Diabetes Mellitus in Ohio State the percentage of diabetic patients in the U.S. treated by Primary Care Physicians
More informationHow to Fight Diabetes and Win. Diabetes. Medications
How to Fight Diabetes and Win Diabetes Medications MEDICATIONS FOR DIABETES According to the American Diabetes Association, 85% of adults diagnosed with diabetes take insulin and/or oral medication to
More informationType 2 Diabetes Mellitus hypoglycaemic agents
Type 2 Diabetes Mellitus hypoglycaemic agents Name Metformin Drug Name (eg brand name) Metformin (Diaformin Diabex) Cost / PBS per 28d mth $10.24 (1.5g dly) 1000mg+500mg / $4.44+$5.80 Concerns? Lactic
More informationThe information in this guide comes from a government-funded review of research about pills for type 2 diabetes.
effectivehealthcare.ahrq.gov Pills for Type 2 Diabetes: A Guide for Adults Consumer Summary Guide published 5 Dec 2007 1. Introduction What does this guide cover? Type 2 diabetes means the body has a problem
More informationDiabetes Mellitus II CPG
1 Diabetes Mellitus II CPG Candidates for Screening Integrated Complex Care Patients: Check Yearly Prediabetes: Check Yearly No Diabetes Mellitus (DM) Risk Factors: Check at Age 45, Repeat Every 3 Years
More informationORAL AND INJECTABLE (NON-INSULIN) PHARMACOLOGICAL AGENTS FOR TYPE 2 DIABETES
ORAL AND INJECTABLE (NON-INSULIN) PHARMACOLOGICAL AGENTS FOR TYPE 2 DIABETES Joseph L. Evans, Ph.D., President, P & N Development Ventures, Saint Louis, MO USA Email: jevansphd@earthlink.net Börk Balkan,
More informationUnderstanding Your Diabetes: A Basic Guide
Understanding Your Diabetes: A Basic Guide Table of Contents First Steps to Managing Your Diabetes at Home When Your Blood Sugar is Too High (Hyperglycemia) Blood Sugar Targets and Blood Sugar Log How
More informationDIABETES (1 of 5) Generic. Generic $0 $5 $5-10 $0 $0 $0. Generic $0 $5 $5-10. Generic. Generic $0 $5 $5-10 $0 $0 $0. Generic $0 $5 $5-10 $0 $0 $0
Metformin DIABETES (1 of 5) Glucophage Glucophage XR ER $7 (500mg) $7 (500mg) $5 $5 500mg, 750mg only 500mg, 750mg only Sulfonylurea/Combinations Amaryl Glucotrol glimepiride glipizide $5 $5 Glucotrol
More informationMultiple Small Feedings of the Mind: Diabetes. Sonja K Fredrickson, MD, BC-ADM March 7, 2014
Multiple Small Feedings of the Mind: Diabetes Sonja K Fredrickson, MD, BC-ADM March 7, 2014 Question 1: Setting A1c Goals Describe the evidence based approach to determining the target HgbA1c in different
More informationWhat s New in Diabetes Medications. Jena Torpin, PharmD
What s New in Diabetes Medications Jena Torpin, PharmD 1 Objectives Discuss new medications in the management of diabetes Understand the mechanism of the medications discussed Understand the side effects
More informationGlycemic Management of Type 2 Diabetes. Gail Nunlee-Bland, M.D. Professor Medicine & Pediatrics Director, Diabetes Treatment Center Howard University
Glycemic Management of Type 2 Diabetes Gail Nunlee-Bland, M.D. Professor Medicine & Pediatrics Director, Diabetes Treatment Center Howard University 1 None Disclosures Learning Objectives Understand the
More informationSide Effects of: GLP-1 agonists DPP-4 inhibitors SGLT-2 inhibitors. Bryce Fukunaga PharmD April 25, 2018
Side Effects of: GLP-1 agonists DPP-4 inhibitors SGLT-2 inhibitors Bryce Fukunaga PharmD April 25, 2018 Objectives For each drug class: Identify the overall place in therapy Explain the mechanism of action
More informationClinical Pharmacotherapeutic Applications of the American Diabetes Association Standards of Care 2018
Clinical Pharmacotherapeutic Applications of the American Diabetes Association Standards of Care 2018 RACHEL NAIDA, PHARMD, CDE CLINICAL ASSOCIATE PROFESSOR UNIVERSITY OF NEW ENGLAND COLLEGE OF PHARMACY
More informationThe Death of Sulfonylureas? A Review of New Diabetes Medications
The Death of Sulfonylureas? A Review of New Diabetes Medications Kelly Hoenig, Pharm.D., BCPS Cedar Rapids Family Medicine Residency 2/4/17 Objectives Review GLP-1 Agonists, DPP-IV Inhibitors and SGLT-2
More informationDiabetes Update 2018: Challenging Transitions. Patricia A. Daly, MD, FACP, FACE Medical Director for Diabetes Valley Health System
Diabetes Update 2018: Challenging Transitions Patricia A. Daly, MD, FACP, FACE Medical Director for Diabetes Valley Health System 1 Patricia A. Daly, MD, FACP, FACE Medical Director for Diabetes Valley
More informationErtugliflozin (Steglatro ) 5 mg daily. May increase to 15 mg daily. Take in the morning +/- food. < 60: Do not initiate; discontinue therapy
Sodium-glucose Cotransporter-2 (SGLT2) s Inhibit SGLT in proximal renal tubules, reducing reabsorption of filtered glucose from tubular lumen Lowers renal threshold for glucose à increase urinary excretion
More informationNew Therapies for Diabetes
Type 2 diabetes is increasingly prevalent New Therapies for Diabetes Lynn Mack, M.D. Associate Professor Diabetes, Endocrinology, & Metabolism The Nebraska Medical Center lmack@unmc.edu No Conflicts of
More informationUpdate on Therapies for Type 2 Diabetes: Angela D. Mazza, DO July 31, 2015
Update on Therapies for Type 2 Diabetes: 2015 Angela D. Mazza, DO July 31, 2015 Objectives To present the newer available therapies for the management of T2D To discuss the advantages and disadvantages
More informationNewer Drugs in the Management of Type 2 Diabetes Mellitus
Newer Drugs in the Management of Type 2 Diabetes Mellitus Dr. C. Dinesh M. Naidu Professor of Pharmacology, Kamineni Institute of Medical Sciences, Narketpally. 1 Presentation Outline Introduction Pathogenesis
More informationDiabetes Update 2018: Challenging Transitions. Patricia A. Daly, MD, FACP, FACE Medical Director for Diabetes Valley Health System
Diabetes Update 2018: Challenging Transitions Patricia A. Daly, MD, FACP, FACE Medical Director for Diabetes Valley Health System 1 Patricia A. Daly, MD, FACP, FACE Medical Director for Diabetes Valley
More informationUpdate on Diabetes Mellitus
Update on Diabetes Mellitus Treatment: Targeting the Incretin System Overview Underlying defects with Type 2 diabetes Importance of managing postprandial glucose control Amylin Incretin Hormones New therapies
More informationPharmacology. Kacy Aderhold, MSN, APRN-CNS, CMSRN
Pharmacology Kacy Aderhold, MSN, APRN-CNS, CMSRN Biguanides Decreases hepatic glucose production and improves insulin sensitivity (increases number of insulin receptors) Common Adverse Reaction: diarrhea
More informationDrug Class Review Newer Diabetes Medications and Combinations
Drug Class Review Newer Diabetes Medications and Combinations Final Update 2 Report July 2016 The purpose reports is to make available information regarding the comparative clinical effectiveness and harms
More informationGlucose Control drug treatments
Glucose Control drug treatments It should be noted that glitazones are under suspicion of precipitating acute cardiac events and current recommendations contraindicate the use of glitazones in patients
More informationAntidiabetic Agents CHAPTER BIGUANIDES
ajt/shutterstock, Inc. CHAPTER 2 Antidiabetic Agents Charles Ruchalski, PharmD, BCPS BIGUANIDES For newly diagnosed patients with type 2 diabetes, the biguanide metformin is the drug of choice for initial
More informationHealthy You: A Guide to Diabetes Self-Care SURVIVAL SKILLS
Healthy You: A Guide to Diabetes Self-Care SURVIVAL SKILLS Table of Contents Introduction 3 Monitoring Your Diabetes 7 Medications 11 Problem Solving 24 Healthy Eating with Diabetes 26 Managing Sick Days
More informationManagement of Type 2 Diabetes Mellitus. Heather Corn, MD, MS Endocrinology, Diabetes, and Metabolism
Management of Type 2 Diabetes Mellitus Heather Corn, MD, MS Endocrinology, Diabetes, and Metabolism Disclosures Working for Intermountain Healthcare Some of the views represented are the opinion of ABIM-certified
More informationThe Community Pharmacist s Role in Diabetes Treatment
CONTINUING EDUCATION The Community Pharmacist s Role in Diabetes Treatment By Kimberly Ference, PharmD U pon completion of this activity, the pharmacist should be able to achieve these directives: 1. Describe
More informationDiabetes Management: A diagnostic perspective
Diabetes Management: A diagnostic perspective Images: http://www.engadget.com/2009/09/23/bayer-introduces-countour-usb-glucose-meter/ http://www.medtronicdiabetes.com/treatment-and-products/minimed-530g-diabetes-system-with-enlite
More informationYOU HAVE DIABETES. Angie O Connor Community Diabetes Nurse Specialist 25th September 2013
YOU HAVE DIABETES Angie O Connor Community Diabetes Nurse Specialist 25th September 2013 Predicated 2015 figures are already met 1 in 20 have diabetes:1in8 over 60years old Definite Diagnosis is key Early
More informationDeaths Hospitalizations Company. Takeda Pharmaceuticals. Takeda Pharmaceuticals. Takeda Pharmaceuticals. Janssen Pharmaceuticals
Takeaways: Diabetes Drug Investigation From: BSardi@aol.com Sent: Mon, Dec 22, 2014 at 10:51 am To: Cc: gemcap2@reagan.com martie.whittekin@verizon.net, katjames008@gmail.com clip_image002.jpg (64.5 KB)
More informationDept of Diabetes Main Desk
Dept of Diabetes Main Desk 01202 448060 Glucose management in Type 2 Diabetes in Adults The natural history of type 2 diabetes is for HbA1c to deteriorate with time. A stepwise approach to treatment is
More informationImproving Patient Outcomes with Individualized Therapy in the Management of Type 2 Diabetes
Improving Patient Outcomes with Individualized Therapy in the Management of Type 2 Diabetes Timothy S. Reid, M.D. Mercy Diabetes Center Janesville, WI Duality Statement Dr. Reid is a Speaker and Consultant
More informationPharmacology Update for the Adult Patient - Newer Oral Medications for Diabetes
Pharmacology Update for the Adult Patient - Newer Oral Medications for Diabetes Brooke Hudspeth, PharmD, CDE, MLDE Director of Diabetes Prevention, Kroger Pharmacy Adjunct Assistant Professor, University
More informationJoslin Diabetes Center Joslin Diabetes Forum 2013: The Impact of Comorbidities on Glucose Control Scenario 2: Reduced Renal Function
Scenario 2: Reduced Renal Function 62 y.o. white man with type 2 diabetes for 18 years Hypertension and hypercholesterolemia Known proliferative retinopathy Current medications: Metformin 1000 mg bid Glyburide
More information2/17/2016. Objectives. Define. Hey Sugar! DMII Management in Hospice Care
Hey Sugar! DMII Management in Hospice Care Michelle Huber, R.Ph., PharmD.,CGP Objectives Review treatment for hyperglycemia discussing how these medications work, hypoglycemia risk, special considerations.
More informationHow can we improve outcomes in Type 2 diabetes?
How can we improve outcomes in Type 2 diabetes? Earlier diagnosis Better patient education Stress central role of lifestyle management Identify and treat all risk factors Use rational pharmacological therapy
More informationDisclosure. Learning Objectives. Case. Diabetes Update: Incretin Agents in Diabetes-When to Use Them? I have no disclosures to declare
Disclosure Diabetes Update: Incretin Agents in Diabetes-When to Use Them? I have no disclosures to declare Spring Therapeutics Update 2011 CSHP BC Branch Anar Dossa BScPharm Pharm D CDE April 20, 2011
More informationCopyright 2003 How long does it take metformin to lower blood sugar. All rights reserved.
How long does it take to see results with invokana on lowering your sugar reading?. Diabetes In Control. A free weekly diabetes newsletter for Medical Professionals. News and information for Medical Professionals.
More informationModulating the Incretin System: A New Therapeutic Strategy for Type 2 Diabetes. Overview. Prevalence of Overweight in the U.S.
Modulating the Incretin System: A New Therapeutic Strategy for Type 2 Diabetes Geneva Clark Briggs, PharmD, BCPS Overview Underlying defects with Type 2 diabetes Importance of managing postprandial glucose
More informationTABLE 1A : Formulary Coverage of Insulin Therapies & Indications for Use in Various Populations
177 TABLE 1A : Formulary Coverage of Insulin Therapies & Indications for Use in Various Populations Formulary Coverage Indication for use with: INSULIN THERAPY NS NB NL PE ADULTS PEDIATRICS PREGNANCY BOLUS
More informationJeffery Davies, DO, MPH, FACOEP ACOEP Chicago, IL October Your DM patient is ready for discharge, now what?
Jeffery Davies, DO, MPH, FACOEP ACOEP Chicago, IL October 2018 Your DM patient is ready for discharge, now what? Financial Disclosures None Objectives 1. Understand follow up patterns/capability of patients
More informationDiabetes management in liver and kidney disease
Diabetes management in liver and kidney disease Epidemiology 1 Clinical case A 59 year old man with alcoholic cirrhosis; portal hypertension; mild encephalopathy Fasting plasma glucose - 103, March 2016;
More informationManaging Complex Diabetes Cases: Medication Update. Celia Levesque MSN, RN, CNS-BC, CDE, BC-ADM
Managing Complex Diabetes Cases: Medication Update Celia Levesque MSN, RN, CNS-BC, CDE, BC-ADM clevesqu@mdanderson.org Objectives Describe how each diabetes medication class is used to treat diabetes Differentiate
More informationA New Therapeutic Strategey for Type II Diabetes: Update 2008
Live, One Hour Webinar A New Therapeutic Strategey for Type II Diabetes: Update 2008 Geneva Clark Briggs, PharmD, BCPS Adjunct Professor at University of Appalachia College of Pharmacy in Grundy, Virginia.
More informationDipeptidyl-Peptidase 4 (DPP-4) Inhibitors Drug Class Prior Authorization Protocol
Dipeptidyl-Peptidase 4 (DPP-4) Inhibitors Drug Class Prior Authorization Protocol Line of Business: Medicaid P&T Approval Date: February 21, 2018 Effective Date: April 1, 2018 This policy has been developed
More informationDrug Therapy in Diabetes HEATHER TINGLE UK COLLEGE OF PHARMACY, PY4
Drug Therapy in Diabetes HEATHER TINGLE UK COLLEGE OF PHARMACY, PY4 OVERVIEW Characteristic Type 1 DM (10%) Type 2 DM (90%) Formerly known as Juvenile; Insulin-dependent Adult onset; Non-insulin dependent
More informationAdvanced Practice Education Associates. Endocrine
Advanced Practice Education Associates Endocrine Overview Diabetes Thyroid Disease 162 Copyright 2016 Advanced Practice Education Associates DIABETES MELLITUS What is the BMI cut point for screening adults
More informationDate of Review: September 2016 Date of Last Review: September 2015
Copyright 2012 Oregon State University. All Rights Reserved Drug Use Research & Management Program Oregon State University, 500 Summer Street NE, E35 Salem, Oregon 97301-1079 Phone 503-947-5220 Fax 503-947-1119
More informationDiabetes Update Bryan Heart Conference September 5, 2015 Shannon Wakeley, MD. Disclosures. Objectives 9/1/2015
Diabetes Update Bryan Heart Conference September 5, 2015 Shannon Wakeley, MD Disclosures I speak on behalf of the following companies: Astra Zeneca, Boehringer Ingelheim, Johnson & Johnson, Sanofi and
More informationDrug Class Monograph
Drug Class Monograph Class: Dipeptidyl-Peptidase 4 (DPP-4) Inhibitors Drugs: alogliptin, alogliptin/metformin, Januvia (sitagliptin), Janumet (sitagliptin/metformin), Janumet XR (sitagliptin/metformin),
More informationGlucagon-Like Peptide (GLP-1) Receptor Agonists Clinical Edit Criteria
Glucagon-Like Peptide (GLP-1) Receptor Agonists Clinical Edit Criteria Drug/Drug Class: Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Superior HealthPlan follows the guidance of the Texas Vendor Drug
More informationHot Topics: The Future of Diabetes Management Cutting Edge Medication and Technology-Based Care
Hot Topics: The Future of Diabetes Management Cutting Edge Medication and Technology-Based Care Mary Jean Christian, MA, MBA, RD, CDE Diabetes Program Coordinator UC Irvine Health Hot Topics: Diabetes
More informationDIABETES. Mary Bruskewitz APNP, MS, BC-ADM Clinical Nurse Specialist Diabetes. November 2013
DIABETES Mary Bruskewitz APNP, MS, BC-ADM Clinical Nurse Specialist Diabetes November 2013 mbruskewitz@outlook.com Objectives Part 1 Overview of Endocrine Physiology Pathophysiology of Diabetes Diabetes
More informationDrug Class Monograph
Class: Dipeptidyl-Peptidase 4 (DPP-4) Inhibitors Drug Class Monograph Drugs: alogliptin, Januvia (sitagliptin), Janumet (sitagliptin/metformin), Janumet XR (sitagliptin/metformin), Jentadueto (linagliptin/metformin),
More informationFee-for-Service Pharmacy Provider Notice #216 ** March 2016 PDL Changes ** Existing Drug Classes
Fee-for-Service Pharmacy Provider Notice #216 ** March 2016 PDL Changes ** December 19, 2016 Please be advised that the Department for Medicaid Services (DMS) is making changes to the Kentucky Medicaid
More informationTABLE 1A: Formulary Coverage of Insulin Therapies & Indications for Use in Various Populations
177 TABLE 1A: Formulary Coverage of Insulin Therapies & Indications for Use in Various Populations TABLE 1A : Formulary Coverage of Insulin Therapies & Indications for Use in Various Populations Formulary
More informationTreatment Options for Diabetes: An Update
Treatment Options for Diabetes: An Update A/Prof. Marg McGill Manager, Diabetes Centre Dr. Ted Wu Staff Specialist Endocrinologist Diabetes Centre Centre of Health Professional Education Education Provider
More informationUpdate on Diabetic Medications UMA SUNDARAM, M.D. DIABETES & ENDOCRINE ASSOCIATES APRIL 07, 2018
Update on Diabetic Medications UMA SUNDARAM, M.D. DIABETES & ENDOCRINE ASSOCIATES APRIL 07, 2018 Disclosure NONE Objectives To identify different categories of diabetes medications Understand the pharmacology
More informationWhat s New on the Horizon: Diabetes Medication Update
What s New on the Horizon: Diabetes Medication Update Outline of Talk Newly released and upcoming medications: the incretins, DPP-IV inhibitors, and what s coming Revised ADA/EASD and AACE guidelines:
More information2018 Diabetes Summit Managing Diabetes: An Art and a Science
2018 Diabetes Summit Managing Diabetes: An Art and a Science Natasha Petry, PharmD, BCACP NDSU College of Health Professions, School of Pharmacy, Department of Pharmacy Practice Patient-Centered Medical
More informationAdult Diabetes. Practice Guidelines Pharmaceutical Management Algorithms. 7 th Edition, 2014
Adult Diabetes Practice Guidelines Pharmaceutical Management Algorithms 7 th Edition, 2014 2 DEVELOPED BY IU Health Physicians Diabetes Educators Lauren Baker, MD, Medical Director DEDICATED TO Corbin
More informationRebecca Newberry APRN MS CDE
Current Diabetes Medications Nursing Implications and Applications Rebecca Newberry APRN MS CDE Methodist Center for Diabetes and Nutritional Health Disclosures Objectives Speakers Bureaus/Consulting Board
More informationNew Medications and Prescribing Methods for Diabetic Patients
New Medications and Prescribing Methods for Diabetic Patients Jeffrey Stroup, PharmD, BCPS, FCCP Professor of Medicine Oklahoma State University Center for Health Sciences Department of Internal Medicine
More informationWhat s New on the Horizon: Diabetes Medication Update. Michael Shannon, MD Providence Endocrinology, Olympia WA
What s New on the Horizon: Diabetes Medication Update Michael Shannon, MD Providence Endocrinology, Olympia WA 1 Outline of Talk Newly released and upcoming medications: the incretins, DPP-IV inhibitors,
More informationDIABETES UPDATE 2018
DIABETES UPDATE 2018 Jerome V. Tolbert, M.D., Ph.D. Assistant Professor of Medicine Icahn School of Medicine at Mt. Sinai Division of Endocrinology and Bone Diseases 317 East 17 th Street New York, New
More information