Index. Note: Page numbers of article titles are in boldface type.

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1 Note: Page numbers of article titles are in boldface type. A Acetyl CoA oxidation of in postpartum period, 287 Acidifying feeds in transition dairy cow management, 374 Adipose tissues derivatives of, insulin-stimulated glucose uptake by, NEFAs and BHB in, Age as factor in transition dairy cow management, Alkaloid(s) endophyte in transition cow management, Amino acids in glucose supply, 301 in transition cow management, B BHB. See b-hydroxybutyrate (BHB) Body condition management of in decreasing metabolic disorders, Body condition score infectious diseases and, in metabolic disease prevention in dairy cows, accuracy of, 325 assessment and management of, health related to, introduction, periparturient metabolic diseases and, in transition cow management, Bone in energy metabolism in transition dairy cow management, C Calcium oral supplementation of Vet Clin Food Anim 29 (2013) vetfood.theclinics.com /13/$ see front matter ª 2013 Elsevier Inc. All rights reserved.

2 458 Calcium (continued) in peripartum dairy cows, introduction, 447 subcutaneous treatment, timing relative to calving, 454 types of, in transition dairy cow management, vitamin D and in transition dairy cow management, 374 Calcium binding zeolites and in transition dairy cow management, Calcium drenches in transition dairy cow management, 375 Calving metabolic change around nature of, Clinical milk fever oral calcium supplements for, subclinical hypocalcemia vs., D Dairy cows. See also Transition dairy cow(s) condition of assessment of, glucose metabolism in, See also Glucose metabolism, in dairy cows insulin resistance in, See also Insulin resistance, in dairy cows lactating ketosis treatments in, See also Ketosis treatments, in lactating dairy cows metabolic diseases in prevention of body condition score in, See also Body condition score, in metabolic disease prevention in dairy cows peripartum oral calcium supplements in, See also Calcium, oral supplementation of, in peripartum dairy cows transition. See Transition dairy cow(s) Dairy herds metabolic health in assessment of, composite indices of inflammation in, introduction, laboratory procedures in, minimizing extraneous sources of variation in blood analyte concentrations in, DCAD. See Dietary cation-anion difference (DCAD) Dextrose in lactating dairy cows, 437 Diabetes mellitus insulin secretion and,

3 459 Diet formulation and grouping strategy in decreasing metabolic disorders, Dietary cation-anion difference (DCAD) in transition dairy cow management, DMI. See Dry matter intake (DMI) Dry matter intake (DMI) depression of metabolic diseases related to, reduced in transition cow management, E Endophyte alkaloids in transition cow management, Energy metabolism of in transition dairy cow management bone in, in transition dairy cow management, F Fat(s) in transition cow management, Fatty acids in transition cows inflammation altered by, Fatty liver body condition score and, 329 Feed intake depressed metabolic diseases related to, metabolic control of, introduction, ketosis treatments in relation to, in postpartum period, oxidation of acetyl CoA, 287 oxidation of NEFA in liver, propionate and lipolytic state interaction, supply of TCA intermediates, 287 TCA activity and control of OXPHOS, regulation types, signal from hepatic oxidation of fuels, energy charge in liver, 283 fuels oxidized in liver, 283 propionate effects, 284 strategies in, diet formulation and grouping strategy, managing body condition, stress reduction, 292

4 460 Fresh cows metabolic disease of metabolic control of feed intake effects on, See also Feed intake, metabolic control of Fuel(s) hepatic oxidation of signal from, G Genetic(s) effects on insulin effects on glucose metabolism, 308 Glucocorticoid(s) in lactating dairy cows, Glucose metabolism in dairy cows, glucose supply, insulin effects on genetic influences on, 308 quantitative aspects of, 310 Glucose removal mechanisms of, Glucose uptake mechanisms of, Glycerol in glucose supply, 301 Glycogen in glucose supply, 301 H Health body condition score and, metabolic in dairy herds assessment of, See also Dairy herds, metabolic health in, assessment of HEC test. See Hyperinsulinemic euglycemic clamp (HEC) test Hepatic Oxidation Theory (HOT), HOT. See Hepatic Oxidation Theory (HOT) b-hydroxybutyrate (BHB) physiology of, during transition period, diagnostic test accuracy, incidence vs. prevalence testing, ketone bodies, likelihood ratios and predictive values, sensitivity and specificity, introduction, 388 Hyperinsulinemic euglycemic clamp (HEC) test in measuring insulin resistance,

5 461 Hypocalcemia subclinical oral calcium supplements for, vs. clinical milk fever, I Infectious diseases body condition score and, Inflammation in transition cows fatty acids altering, impact on metabolism, metabolic stress and, oxidative stress and, Inflammatory response in transition cows, Insulin effects on glucose metabolism genetic influences on, 308 in lactating dairy cows, Insulin resistance in dairy cows, effects in specific tissues, glucose removal, glucose uptake mechanisms, measurement of, considerations in, HEC test in, IVGTT in, IVITT in, 314 surrogate indexes in, defined, 303 as homeorhetic mechanism during pregnancy and lactation, 306 Insulin secretion diabetes mellitus and, Insulin-stimulated glucose uptake by skeletal muscle and adipose tissue, general aspects of, derivatives of adipose tissue, genetic influences on effects of insulin on glucose metabolism, 308 glucose output from liver, 309 insulin resistance as homeorhetic mechanism during pregnancy and lactation, 306 NEFAs release from adipose tissue, protein metabolism of skeletal muscle, liver, and other peripheral tissues, Intravenous glucose tolerance test (IVGTT) in measuring insulin resistance, Intravenous insulin tolerance test (IVITT) in measuring insulin resistance, 314

6 462 IVGTT. See Intravenous glucose tolerance test (IVGTT) IVITT. See Intravenous insulin tolerance test (IVITT) K Ketosis body condition score and, 330 in lactating dairy cows early lactation physiology of, 434 Ketosis treatments in lactating dairy cows, background of, 435 classification of, combination therapies, dextrose, 437 glucocorticoids, insulin, introduction, 433 materials and methods, 435 propylene glycol, review of results of, systemic, vitamin B 12 /phosphorus combination product, in relation to metabolic control of feed intake, L Lactate in glucose supply, 301 Lipid(s) mobilization of impact on liver function in transition cow management, Lipid metabolism physiology of, homeostatic and homeorhetic mechanisms in, lipogenesis in, lipolysis in, NEFA metabolism in, 328 Lipogenesis in lipid metabolism, Lipolysis in lipid metabolism, Lipolytic state propionate and in postpartum period, Liver BHB in, energy charge in, 283

7 463 fatty body condition score and, 329 fuels oxidized in, 283 lipid mobilization effects on in transition cow management, NEFAs in, oxidation of in postpartum period, M Magnesium in transition dairy cow management, Mammary gland NEFAs and BHB in, 390 Metabolic changes calving-related nature of, Metabolic disease(s) in dairy cows prevention of body condition score in, See also Body condition score, in metabolic disease prevention in dairy cows depressed feed intake and, periparturient body condition score and, Metabolic health in dairy herds assessment of, See also Dairy herds, metabolic health in, assessment of Metabolic stress in transition cows, inflammation related to, Metabolism micromineral in transition dairy cow management, in transition cows inflammation effects on, Methyl donors in transition cow management, Micromineral metabolism in transition dairy cow management, Milk fever body condition score and, clinical oral calcium supplements for, vs. subclinical hypocalcemia, control of in transition dairy cow management, 368 Mycotoxin(s) in transition cow management,

8 464 N NEB. See Negative energy balance (NEB) NEFAs. See Nonesterified fatty acids (NEFAs) Negative energy balance (NEB) excessive negative downstream outcomes and cow-level association of, diseases and culling, reproduction and milk production, herd-level association of, evaluating individual animal tests at herd level, herd alarm levels, sample frequency, sample size for herd-based test, sources of error in herd testing, Nonesterified fatty acids (NEFAs) metabolism of, 328 oxidation in liver in postpartum period, physiology of, during transition period, diagnostic test accuracy, incidence vs. prevalence testing, ketone bodies, likelihood ratios and predictive values, sensitivity and specificity, introduction, 388 recommendations, Nutrient(s) fetal demand for, 341 O Oxidative phosphorylation (OXPHOS) control of TCA activity and in postpartum period, Oxidative stress in transition cows inflammation related to, OXPHOS. See Oxidative phosphorylation (OXPHOS) P Peripartum period lipolytic state of cows in, 280 oral calcium supplements in dairy cows during, See also Calcium, oral supplementation of, in peripartum dairy cows Periparturient metabolic diseases body condition score and,

9 465 Phosphorus in transition dairy cow management, 372 Postpartum period control of feed intake in, See also Feed intake, metabolic control of, in postpartum period Propionate effects on feed intake, 284 in glucose supply, 300 lipolytic state interaction and in postpartum period, Propylene glycol in lactating dairy cows, Protein(s) in transition dairy cow management, , R Rumen NEFAs and BHB in, 389 Rumen modifiers in transition cow management, S Skeletal muscle insulin-stimulated glucose uptake by, Somatotropin in transition cow management, 353 Stress metabolic in transition cows, inflammation related to, oxidative in transition cows inflammation related to, Stress reduction in decreasing metabolic disorders, 292 T TCA. See Tricarboxylic acid (TCA) Toxin(s) in transition cow management, Transition cow disorders factors affecting, intervention strategies, 276 introduction, Transition dairy cow(s) management of, acidifying feeds in, 374 acidosis and,

10 466 Transition (continued) after calving, 374 age as factor in, amino acids in, body condition score in, bone in energy metabolism in, calcium drenches in, 375 calcium in, with vitamin D, 374 changes to successful adaptation, reduced DMI, DCAD in, endophyte alkaloids in, energy intake in, 343 energy reserves in, 343 fats intake in, integrated interventions in cohort study of, 377 introduction, , lipid mobilization in liver effects of, magnesium in, methyl donors in, micromineral metabolism in, milk fever control in, 368 mycotoxins in, optimum duration of exposure in, 372 phosphorus in, 372 protein in, intake before calving, protein reserves in, recommendations, 356 rumen modifiers in, somatotropin in, 353 toxins in, troubleshooting/formulation in, vitamin D and calcium in, 374 zeolites and calcium binding in, physiologic adaptations of, inflammatory response, and metabolic stress link between, metabolic stress, and inflammatory response link between, Tricarboxylic acid (TCA) activity control of OXPHOS and in postpartum period, Tricarboxylic acid (TCA) intermediates supply of in postpartum period, 287

11 467 V Vitamin B 12 /phosphorus combination product in lactating dairy cows, Vitamin D calcium and in transition dairy cow management, 374 Z Zeolite(s) calcium binding and in transition dairy cow management,